Module Title INTRODUCTORY BIOCHEMISTRY Module Number STF 4003 JACS Subject Code(s) and % of each subject C720 ASC Category(ies) 3 Level (0‐M) Credits ECTS Credit % Taught in Welsh Module Type 4 20 10 0% Standard Taught Module Teaching Period Pre‐requisites Term 1,2,3 None Module Leader School(s) Campus Dr. Tryfon Adamidis Perrotis College Perrotis College Assessment Methods Assessment Type Duration/Length of Weighting of Assessment Approximate Date of Assessment Type Submission Course work and Equivalent to 3000 50% February Practical report Examination 2 hours 50% May Students need to achieve a minimum of 25% in each element, in addition to a module average of 40% or above in order to successfully pass the module. Any elements marks below 25% would automatically require the students to retrieve that particular failed element (regardless of overall module mark). Aim(s) • • • • • To provide students with a basic introduction to the chemistry involved in food and biological system. To study the structure of important biological molecules To train students laboratory skills To explore the relationship between structure and role of selected compounds in biological systems To establish basic biochemical principles and to demonstrate the dynamic nature of cells and their constituents • Learning Outcomes At the end of this module, the student will be able to: 1. Describe the basic concepts of chemical sciences as applied to biological macromolecules. 2. Describe the structure and function of a range of biological molecules including carbohydrates, amino acids/proteins, and lipids. 3. Describe the structure of cells and their organelles. 4. Explore the connections between chemical structure and biological importance. 5. Gain an understanding of the role of macro‐ and micro‐nutrients in foodstuffs. 6. Outline a range of catabolic pathways responsible for the metabolism of nutrients and the generation of energy. 7. Outline a range of anabolic pathways responsible for the synthesis of biological macromolecules and the storage of energy. Learning and Teaching Delivery Methods Lectures 44 hours Practical 14 hours Tutorials 8 hours Optional workshops 5 hours Supporting material available on Blackboard Indicative content Term One Basic atomic structure, relationship between inorganic and organic chemistry Physical and Inorganic chemistry: • • • • Water and electrolytes, pH, acids – bases and salts, preparation and relevance of buffers, morality, solutions and colloids Chemical bonds, atom and atomic structure Introduction to Spectroscopy Introduction to metabolism: 1 Organic chemistry and macronutrients: • • • • Chemistry of proteins , peptides and amino acids and Enzymes Chemistry of lipids, fatty acids, phospholipids and triacylglycerols Chemistry of carbohydrates, poly sacchardies, di and mono Chemistry of organic acid and vitamins The module will continue in the second term indicating the following elements which complete the Introductory Biochemistry module. Term Two: • Cellular structure and function. • Structure and function of animal and plant carbohydrates. • Structure and function of enzymes to include classification, active sites, kinetics, allosterism, coenzymes. • Structure and function of fatty acids, steroids, phospholipids and triacylglycerols. • Energy production by biological oxidation systems including glycolysis, TCA cycle, oxidative phosphorylation, high energy compounds. • Inter‐relationships between Fat, Amino Acid and Carbohydrate metabolism. • Specific and general control mechanisms. • Dietary requirements with regard to essential and non‐essential amino acids, fatty acids etc. Recommended Reading • Nelson, D. L; Cox, M. M; Lehninger, A. L (2013), Lehninger – Principles of Biochemistry, (6TH EDITION), Freeman and company • Campbell, M. K & Farrell, S.O (2011), Biochemistry, (7thEdition) Brooks/Cole, CA, USA. • Berg, J.M, Tymoczko, J.L, Stryer, Lubert (2011), Biochemistry, (7th Edition), Freeman, NY, USA • Hames, B. D & Hooper, N. M (2011), Biochemistry, (4th Edition), Garland Science, , NY, USA • Lehman, J. W (2010), Multiscale operational organic chemistry: a problem‐solving approach to the laboratory course, 2nd Prentice Hall, • Aleyamma N, (2008) Organic chemistry: how organic chemistry works, (2nd Edition), Abergele, Norwich UK • Baird, C (2006) Chemistry in Your Life. (2nd Edition) Freeman • Sutton, R. et al. (2009) Chemistry for Life Sciences.( 2nd Edition) Taylor & Francis • Hames B.D & Hooper N (2005), Instant Notes in Biochemistry , (3rd Edition), BIOS Taylor & Francis, NY,USA • Alais, C. & Linden, G. (1991). Food Biochemistry. Ellis Horwood. Virginia, USA Access to Specialist Requirements Moodle Software Coursework practical report 50% term one Examination 50% term two