Poster Presentations "Gradient Sensing and Directed Cell Migration" 2005 Poster Presenter / Organization Poster Title Poster Sessions - Monday and Tuesday Group A Natalie Andrew The University of Birmingham Coupling Directional Sensing to Pseudopod Formation Eberhard Bodenschatz Cornell University/Max Planck Society Studying Chemotaxis with Micorfluidic Devices Gary Bokoch TSRI Rac regulates tail retraction during neutrophil chemotaxis Till Bretschneider Max-Planck-Institut Fuer Biochemie Subsecond Reorganization of the Actin Network in Dictyostelium Ruey-Hwa Chen National Taiwan University The tumor suppressor DAPK inhibits motility by perturbating integrin-mediated migrational polarity Chang Chung Vanderbilt University Medical Center Role of WASP-interacting protein (WIP) in the regulation of F-actin polymerization at the leading edge of chemotaxing cells Frank Comer National Institutes of Health Multiple Roles for CRAC in Chemoattractant Signaling Louise Cramer University College London Microtubules spatially regulate ADF/cofilin to guide migrating cells Xuemei Dong University of Connecticut Health Center Roles of the guanine-nucleotide exchange factor Prex1 in chemoattractant-induced neutrophil Dirk Dormann University of Dundee Cell movement in a multicellular tissue: Analysis of the actin cytoskeleton in Dictyostelium slugs Chad Green University of California, Davis Distinct activation pathways regulate neutrophil polarization and CD18 distribution in shear flow Paul Heid University of Iowa Computer-Assisted Reconstruction and Analysis of Filopod Formation and the Role of Myosin II Heavy Chain Phosphorylation in Dictyostelium chemotaxis Bryan Heit University of Calgary Differential activation and utilization of Mac-1 and LFA1 during neutrophil chemotaxis to IL-8 and fMLP. Miho Iijima Johns Hopkins University How cells sense and move to the chemoattractant gradients Ehsan Jabbarzadeh Drexel University Simulation of cell chemotaxis in 2D random porous domains Chris Janetopoulos Johns Hopkins University Phosphoinositide-Linked Polarity Circuits During Cell Migration Tian Jin NIAID/NIH Quantitative imaging of single live cells reveals spatiotemporal dynamics of multi-step signaling events of chemoattractant gradient sensing in Dictyostelium Leung Kim Florida International University Concerted regulation of ROS Signaling and Eukaryotic Chemotaxis Mikkel Klausen Technical University of Denmark Involvement of bacterial migration in development of P. aeruginosa PAO1 biofilms Paul Kriebel National Cancer Institute Vesicles and vesicle trafficking are important for the proper cellular distribution and efficient activation of adenylyl cyclase in chemotaxing cells. Prabhat Kunwar New York University Medical Center Tre1, a Novel G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells Anja Lambrechts Universiteit Gent A central role of profilin I in regulating neurite outgrowth of PC12 cells. Paul Langridge MRC LMB Mutants in the Arp2/3 complex of Dictyostelium discoideum Lawrence Leclaire University of California, San Francisco Daniel Lerner Cornell University Nck-interacting kinase modulates actin cytoskeleton assembly and dynamics in migrating cells Lsc/p115 RhoGEF is required for normal polarization and adhesion of chemoattractant-stimulated neutrophils Nick Leslie University of Dundee PTEN and TPTE inhibit cell migration through their protein phosphatase activity Lixin Liu University of Calgary Essential Role for Leukocyte PI3K? in Leukocyte Emigration In Vivo Hongbo Luo Children's Hospital and Harvard Medical School Ins(1,3,4,5)P4 as a negative regulator of neutrophil chemotaxis. Santos Manes Centro Nacional de Biotecnologia Signaling pathways regulating lymphocyte migration Carmen Melendez-Vasquez Skirball Institute, NYU School of Medicine Actomyosin Motors and the Mechanism of Myelin Formation Poster Sessions -Wednesday and Thursday Group B Michelle Mendoza University of California smek, a novel suppressor of mek1, regulates cell polarity and chemotaxis in Dictyostelium Nicole Neel Vanderbilt University Medical Center Modulation of CXCR2 Chemokine Receptor Trafficking by RhoB Paul Nuzzi University of Wisconsin The calcium-dependent protease calpain 2 mediates neutrophil polarization and chemotaxis Hitesh Patel University of California, San Francisco A developmentally regulated Na-H Exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis Olivier Pertz The Scripps Research Institute Spatio-temporal analysis of RhoA activity in living migratory cells Fiona Pixley Albert Einstein College of Medicine The Role of CSF-1R Signaling in Macrophage Adhesion and Motility Ann Richmond Vanderbilt University Importance of the LLKIL motif and Rho B in CXCR2 receptor trafficking and chemotaxis Wajeeh Saadi University of California, Irvine Chemotaxis of Metastatic Breast Cancer Cells in Parallel-Gradient Microfluidic Chambers Jiqing Sai Vanderbilt University CXCR2 internalization is important for generation of intracellular signal required for chemotaxis Atsuo Sasaki University of California, San Diego Directional sensing and cell polarity through Ras signaling. Bruce Schaar Stanford University Intrinsic Cellular Mechanisms of Directed Neuronal Migration Ian Schneider North Carolina State University Platelet-derived Growth Factor-mediated Spatial Sensing in Fibroblasts is Governed by Three Regimes of Gradient Sensitivity Hanshuang Shao University of Pittsburgh Spatial Localization of M-Calpain to the Plasma Membrane by PIP2 binding is Required for EGF Receptor-Mediated Calpain Activation Daria Siekhaus NYU School of Medicine Genetic analysis of the migration of Drosophila hemocytes Scott Simon University of California, Davis Distinct activation pathways regulate neutrophil polarization and CD18 distribution in shear flow Brian Stramer University of Bristol Live imaging of inflammation in Drosophila embryos reveals key roles for small GTPases during wound chemotaxis in vivo Justin Sturge Breakthrough Breast Cancer Research Centre Endo180: an endocytic receptor that guides cell motility Matthew Thomas Novartis PI3Kgamma and cell movement into the lung. Hui-Hsin Tsai Case Western Reserve University Netrin-1 mediated dispersal of spinal cord oligodendrocyte precursors is critical for the generation of its correct number. Paula van Hennik Sanquin Research/CLB Role of p38 and p42/44 MAPKs in migration of hematopoietic progenitor cells Douwe Veltman University of Groningen Global inhibition and local stimulation of pseudopodia by Dictyostelium soluble guanylyl cyclase Qian Wang University of Illinois Surface Composition Gradients of Immobilized Cell Signaling Molecules. Epidermal Growth Factor on Gold Zhenglong Wang University of Connecticut Health Center Using RNAi to screen for GEFs that are involved in regulation of T cell chemotaxis Heidi Welch Babraham Institute P-Rex1-deficient mice have impaired neutrophil function. Deborah Wessels University of Iowa The Chemotactic Defect in Shwachman-Diamond Polymorphonuclear Neutrophils Liu Yang Johns Hopkins University Feedback Induced Biphasic Response Muhammad Zaman MIT and Whitehead Institute Tumor Cell Migration in 3D: Computational and Experimental Studies Min Zhao University of Aberdeen Cells' sense of electrical potential gradients Doncho Zhelev Duke University Cytoskeleton dynamics of neutrophils stimulated with fMLP and it’s coupling to the transient generation of downstream signals