VETERINARY HISTOLOGY, VETM*3120 Fall/Winter, 2013-2014 0.75 Credits Calendar Description A lecture and laboratory course emphasizing the microscopic organization of the organs of domestic animals in various physiological states. Correlations between morphology and function of the various cells and tissues comprising the organ system will be studied. Course Coordinator Dr. Brad Hanna, OVC Main Building room 1646D; ext. 54534; e-mail: bhanna@uoguelph.ca Instructors Dr. L. Robertson, OVC Main Building Room 2608; E-mail: Dr. H. Snyman, e-mail: hsnyman@uoguelph.ca Dr. S Yamashiro, OVC Main Building Room 1685, ext. 54924; e-mail: syamashi@uoguelph.ca Mrs. Helen Coates, OVC Main Building Room 3660; ext. 54958; E-mail: hhcoates@uoguelph.ca GTA: Hanna Peacock, E-mail: hpeacock@uoguelph.ca Laboratory Technical Assistant Mrs. Helen Coates Administrative Information For questions regarding academic consideration, continuation of study, academic misconduct, safety, confidentiality, and experiential learning involving use of animals, please refer to the appropriate sections of the OVC Phase 1 website. Course Objectives At the end of the course, students will be able to: - Define, spell and correctly use the vocabulary of Histology Describe and explain the structure and function of cells and tissues and the organization of - organs Identify and differentiate between the fundamental operating principles of different types of microscopes Manipulate a light microscope to view the major histological structures of organs and tissues in common domestic species Identify and interpret the structural details (reconstruction of 3D image) and morphological variations in histological sections of tissues of common domestic species Explain the relationship between tissue/organ structure and function, and relate these concepts to Veterinary Physiology and Veterinary Anatomy Explain the altered morphologic expression of pathological tissues in the progression of disease Evaluation Three laboratory exams comprise 40% of the course grade. The first two are worth 10% each, and the last is worth 20% (see Phase 1 schedule for dates). The final examination is worth 60% of the course grade (40% theory and 20% laboratory). A grade of at least 50% must be obtained on this exam to pass the course. A student who scores less than 50% on this examination, and whose overall grade for the course is less than 50%, will be deemed to have failed the course. A student who scores less than 50% on this examination, but whose overall course grade is 50% or higher, will be assigned a grade of incomplete (INC) and will be required to undertake a conditional examination set by the course coordinator. The conditional exam will require further study of the subject during the summer semester. A student who achieves a grade of 50% or higher on this conditional examination will be deemed to have passed the course and will receive their original course grade. A student who achieves a grade of less than 50% on this conditional exam will be deemed to have failed the course and will be assigned a course grade of 49%. Resources Textbooks, Laboratory Guide and Teaching Aids: (i) (ii) (iii) (iv) (v) Dellmann’s Textbook of Veterinary Histology, edited by Jo Ann Eurell and Brian L. Frappier, 6th Ed (2006) Blackwell Publishing or 5th Ed (1998). Williams and Wilkins Publishing. Textbook of Veterinary Histology by D.A. Samuelson (2007), Saunders, an imprint of Elsevier Inc. Applied Veterinary Histology by W.J. Banks, 1st Ed (1981), 2nd Ed (1986) or 3rd Ed (1992). Williams and Wilkins Publishing Company. Veterinary Histology: A Laboratory Guide for VETM*3120 on line (D2L: Desire to Learn). Color Atlas of Veterinary Histology by Bacha, W.J. and Bacha L. M. Third Edition (2012). Wiley-Blackwell, John Wiley and son Ltd. (vi) DVDs of pre-laboratory lectures (by S. Yamashiro), available on D2L. (vii) Lecture notes, available on D2L. (viii) Website for teaching histology sponsored by CANARIE (www.vethistology.com). (ix) Compuhistology for DVD’s by Godwin Isitor is available in the Learning Commons. (x) Digitized images of the microscopic slides are available on line. Virtual Microscopy by Aperio: http://images.objectivepathology.com, Go to “UoGuelph” – OVC, then VETM-3120. (xi) Colour slides (Kodachromes) are available in the histology teaching lab (3655). Any of (i), (ii) or (iii) and Veterinary Histology – Laboratory Guide, will be sufficient, but any textbooks and atlases of histology may be helpful. Schedule Lecture # 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 Topics Introduction, Histological techniques, Interpretation of Images Epithelium (surface = membranous) Exocrine Glands (glandular epithelium) Nervous Tissue Nervous Tissue Muscle Tissue Muscle Tissue Connective Tissue Connective Tissue Connective Tissue and Cartilage Bone: Osseous tissue Bone and Bone Development Overview of Cell Biology and General Histology General Concept of Endocrine Glands and Hypothalamus Hypothalamus and Hypophysis (Pituitary Gland) Thyroid Gland and Parathyroid Gland Adrenal Gland, Paraganglia and Pineal Gland Kidney Kidney and Urinary Passage Blood: Erythrocyte and Platelet Granulocyte and Agranulocyte Haematopoiesis; Concept, Erythropoiesis Granulo-poiesis Nasal Cavity: Olfactory and Respiratory Mucous Membranes Larynx, Trachea, Bronchi and Bronchioles Lung Parenchyma Oral Cavity, Salivary Gland and Tongue Teeth and Development of Tooth Esophagus and Simple Stomach Simple Stomach Simple Stomach and Compound Stomach Small and Large Intestine Liver Liver and Pancreas Integument: Introduction, Hair and Hair Follicles Hair Follicles and Specialized Glands Mammary Gland, Equine and Bovine Hooves Immune System: Introduction, Thymus and The bursa of Fabricius Lymph Node and Spleen, Spleen, Tonsils ,Peyer’s Patches, Hemal Node and Hemolymph Node Laboratory Schedule Laboratory # Topics 1 Microscopy and Histologic Techniques Demonstration 2 Epithelium 3 Nervous Tissue and Muscle Tissue 4 Heart and Blood Vessels, Cardio-Vascular Module 5 Connective Tissue, Cartilage and Bone 6 Bone and Bone Development 7 Hypothalamus and Hypophysis (Pituitary Gland) 8 9 Thyroid, Parathyroid, Adrenal Gland and Islet of Langerhans Kidney and Urinary Passage 10 Blood: RBC, Platelet and Leukocytes 11 Bone Marrow Cytology 12 Nasal Cavity and Upper Respiratory Tract 13 Intrapulmonary Airways and Lung (parenchyma and stroma) 14 Tongue, Salivary Gland, Teeth and Esophagus 15 Simple and Compound Stomach, Small and Large Intestine 16 Liver and Pancreas 17 Skin and Appendages 18 Mammary Gland and Equine Hoof 19 Thymus and the bursa of Fabricius 20 Lymph Node, Spleen, Tonsils, Hemolymphnode and Hemal Node