Agenda International Workshop on Flavanols in Cardiovascular Health (Consensus conference) 24 Jan 2013 Brussels, Belgium Thursday, 24 Jan 2013 Time Topic Speaker 8.30 Welcome and reception 9.00 Welcome address – Introduction to FLAVIOLA and challenges of cacao flavanols (CF) research. Meeting goals. 9.20 Metabonomics, flavanol analytics and their absorption, Chair: Alan Crozier distribution, metabolism, and excretion (ADME) (WP1) (University of Glasgow) 9.20 Introduction and perspectives Alan Crozier (University of Glasgow) 9.40 CF analytics and food content data bases Catherine Kwik-Uribe (Mars) 10.00 CF metabolism and ADME Marc Merx (University of Düsseldorf) Hagen Schroeter (Mars) 10.20 Refreshments 10.40 Epidemiology, susceptibility and safety (WP2) Chair: Carl Keen (University of California, Davis) 10.40 Introduction and perspectives Carl Keen (University of California, Davis) 11.00 Dietary intake of flavanols and procyanidins in the EU Gunter Kuhnle (University of Reading) Influence of sex, age, dietary background, food matrix, 11.20 and nutrient-nutrient interactions on CF absorption and metabolism Jeremy Spencer (University of Reading) 11.40 Lunch 12.40 CF and cardiovascular health - Outcomes from dietary intervention studies (WP3) Chair: Aedin Cassidy (University of East Anglia) 12.40 Introduction and perspectives Aedin Cassidy (University of East Anglia) 13.00 Outcomes of dietary intervention studies of FLAVIOLA Malte Kelm (University of Düsseldorf) 13.30 Nitrate/Nitrite interactions Eddie Weitzberg (Karolinska Institutet Stockholm) 13.40 Potential mechanisms of action (WP4) Chair: Patricia Oteiza (UC Davis) 13.40 Introduction and perspectives Patricia Oteiza (UC Davis) 2 14.00 Novel consequences of the antioxidant action of flavanols Aalt Bast (Maastricht University) 14.20 Epigenetic variation in diet intervention studies: considerations for a tailored personalized nutrition Wim Vanden Berghe (University of Gent) Flavanol metabolites exert anti-inflammatory effect on 14.40 endothelial cells through modulation of expression of genes and cell signaling pathways Dragan Milenkovic (INRA, Clermont-Ferrand) 15.00 Coffee Round table discussion: Dietary recommendations for 15:20 flavanols and procyanidins intake: How far away are we? Introduction: Joanne Lupton Chair + Moderator: Helmut Sies Panel members: Aedin Cassidy, Alan Crozier, Peter Hollman, Carl Keen, Thomas Lüscher, Joanne Lupton, Patricia Oteiza, Garry Williamson 16.20 Summary and Closing Remarks Joanne Lupton 16:30 End of the conference, aperitif 3