Horse Health & Management BY DENISE STEFFANUS RIPLE CROWN hopeful I’ll Have Another wore a nasal strip for every start in his seven-race career, in which he posted five wins and a game second. With New York being the only state to ban the butterfly patch worn just above the nostrils, the big question leading up to the Belmont Stakes (G1) was how the dual classic winner would fare without his nasal strip. I’ll Have Another was scratched from the Belmont with a tendon injury the day before the race, so we’ll never know how racing without a nasal strip may have affected his performance. But Howard Erickson, D.V.M., Ph.D., at Kansas State University, who participated in the yeoman’s share of the nasal-strip research, thinks it may have made a difference. “It’s hard to say, but it might have,” Erickson commented. “That horse was trained more for longer distances … I’ll Have Another might have had an edge in the Belmont anyway, but I think the Flair nasal strip might have protected his lungs and prevented bleeding and improved gas exchange, but we’ll never know that. I think [the nasal strip] certainly could have improved his stamina.” T How nasal strips work When a horse breathes in, it creates a vacuum that both draws in the soft tissues right behind the horse’s nostrils and may suck blood out of the capillaries of the lungs, worsening bleeding. If the nasal passages are held open by a nasal strip, the theory is that a horse will have to exert less nega- tive pressure (vacuum) on its capillaries to breathe in. Ed Blach, D.V.M., one of the developers of the nasal strip, explained in an interview in 2000 the significance of keeping the nasal passages open. “From a physics standpoint in a very simplistic example, if the airway radius is one inch and it reduces itself by one-tenth of an inch because of the collapse, the multiplier effect it has on the other factors calculates to a 37% reduction,” Blach said. “Basically, you don’t have to affect a significant measurement difference to have a fairly significant effect on pressure.” Not a performance enhancer Controversy persists about whether the commonly used diuretic Salix is a performance enhancer. That same question now arises about nasal strips because of their ability to delay fatigue. Do they enhance performance? “It returns them to normal performance rather than performance enhancement,” Erickson said. “You have the nasal passages collapsing and very negative pressure, and that results in more transmural pressure and bleeding into the lungs. If you have blood within the lungs, you don’t have good gas exchange.” Erickson explained that wearing a nasal strip enables a horse to run as it would if it were not bleeding. “Horses are obligate nasal breathers, unlike human athletes who can breathe through the mouth as well,” he said. “So nasal strips are actually more beneficial for the horse than they are the human athlete.” The only racing jurisdiction that bans nasal strips is the New York Racing Association, which governs Thoroughbred racing only. Standardbred racehorses in New York are permitted to wear nasal strips. After nasal strips first were introduced at the 1999 Breeders’ Cup in Florida, NYRA already was casting a wary eye on the new piece of equipment. Then-NYRA President Terry Meyocks asked racing official Ted Hill, V.M.D., to look into them. One primary concern was that collapsing nasal passages may be nature’s way to prevent dirt and other particles from lodging deep within the horse’s lungs when it breathes in. Meyocks was concerned nasal strips might interfere with these natural defenses by holding a horse’s nasal passages wide open. “That was on the list of questions we had about the product,” Hill said. “I think that was discounted pretty quickly.” Hill said their key concern at the time was the manufacturer’s claims of effectiveness without ample supporting studies. Today, NYRA’s concern Horse Health & Management in this issue 30 July 21, 2012 Healthy Horse: Aiding the healing process Farm Management: Fewer horses on same acreage Product Spotlight: For farm and track (32) (34) (36) THOROUGHBRED TIMES Benoit & Associates What exactly is a Flair nasal strip? The Flair nasal strip is a 4x6-inch butterflyshaped patch that is attached over a horse’s nasal passages about one inch above the nostrils and held in place by a special adhesive. The patch material resembles a cross between cardboard and duct tape. The strip’s spring tension holds the horse’s nasal passages open to maximize air flow is how to regulate nasal strips. If they are a highly effective piece of equipment, as the manufacturer claims, regulations should require a horse that races wearing a nasal strip to wear a strip each time it races. On the other hand, if a nasal strip does not significantly affect performance and therefore does not need to be regulated, the manufacturer needs to concede it has no more impact than a tongue tie or a figure-eight noseband. “We can’t have it both ways—it either is significant or not significant,” Hill said. “What was really the case is that if we were going to treat nasal strips like blinkers or a bar shoe, which have to be announced to the public, what were we going to do if a horse came to the paddock and [the nasal strip] fell off and it couldn’t be put back on?” Hill said. “Should we disregard it, should we scratch the horse? That was never resolved. So we decided we just weren’t going to allow them.” Hill said the ban on nasal strips has not been an issue with trainers, and until I’ll Have Another’s intention to run in the Belmont without a nasal strip, it had not come up for discussion. “I don’t remember a single trainer ever coming to me or any of the other stewards saying they wanted to use [a nasal strip] or wanting to revisit it. So it became a nonissue,” he said. Hill said any horseman who wants to open the discussion about lifting the ban on nasal strips needs to petition the New York State Racing and Wagering Board and NYRA to reopen the discussion. “We’d be happy to do that,” he added. Speaking personally as a veterinarian and not as a steward, Hill said if he were a trainer or owner, he did not know if he would use nasal strips, but he has no objection to them. “I’m not totally convinced by the research,” he said. Pricey strip Prior to the 1999 Breeders’ Cup, nasal strip manufacturer CNS Inc. distributed 4,000 samples of nasal strips to trainers throughout North America. About 30 horses went post- ward in that year’s Breeders’ Cup wearing the strips, including all horses trained by D. Wayne Lukas. After the marketing blitz, nasal strips went on sale at tack shops for $60 for a six-pack. These one-timeuse strips continue to fetch from $10.50 a piece in Kentucky to $13.50 a piece in Florida. While they cost about the same as four elastic racing bandages, several trainers who were asked about the price felt it was too high for the product, while others felt $10 was a small price to pay for reducing bleeding and potentially increasing a horse’s stamina. Nasal strip studies Researchers at Kansas State University designed four studies to test the manufacturer’s claims that nasal strips decrease the work of breathing and reduce exercise-induced pulmonary hemorrhage (EIPH, or “bleeding”). Additional studies were conducted at the University of Illinois at Urbana-Champaign, the University of California-Davis, Michigan State University, and Kentucky Equine Research. With the exception of the early study at the University of Illinois (researchers there concluded nasal strips had no effect), all studies supported the manufacturer’s claims. The studies conducted by Kansas State looked at a variety of aspects: • Researchers compiled statistics for 400 racing Thoroughbreds at Calder Race Course in Florida. Horses wearing a nasal strip had a win percentage 3.4% higher than horses that did not wear a strip. Horses wearing a nasal strip also had a 15% decrease in the interval between races (23 days) compared with the race-to-race interval before wearing a nasal strip (29 days). The study was published in 2007. • A small treadmill study of only six Thoroughbreds exercising at near-maximal effort until fatigue observed how horses fared while wearing a nasal strip alone, while medicated with the bleeder medication furosemide (Salix) alone, and while medicated with furosemide and wearing a nasal strip. The researchers found that wearing a nasal strip was as effective as administering furosemide when it came to delaying the onset of fatigue. • Researchers conducted a similar high-speed treadmill study on five Thoroughbreds. Cells washed out of the horse’s airway (bronchoalveolar lavage) showed that horses wearing a nasal strip bleed less into their lungs. However, the study also concluded, “... there was no further reduction in EIPH when wearing [a nasal strip] and medicated with furosemide.” • Seven horses exercised on a high-speed treadmill with and without a nasal strip showed horses wearing a nasal strip had a significant reduction in red blood cells recovered from their lungs. Studies at other institutions: • U.C.-Davis: At Golden Gate Fields, 23 racing Thoroughbreds administered Salix four hours before they raced were divided into horses wearing a nasal strip and those without a strip. The mean red-blood cell count in bronchoalveolar lavage fluid in horses with severe bleeding was significantly reduced when they wore a nasal strip. • Michigan State: Six horses with and without nasal strips were exercised on a highspeed treadmill. Horses wearing a nasal strip had a reduced vacuum exerted on their airway when breathing in, leading researchers to conclude that nasal strips probably reduce the work of breathing. • Kentucky Equine Research in Lexington used eight Thoroughbreds on a high-speed treadmill for its study comparing nasal-strip use and Salix. Nasal strips reduced the work of breathing, and the researchers concluded that the energy spared by nasal strips could benefit muscles of locomotion.—Denise Steffanus FLAIR®:;907:9,+<*,3<5.)3,,+05. WITHOUT DRUGS Are you doing all you can to protect your horse’s lungs from bleeding? WITHOUT WITH FLAIR Nasal Strips FLAIR Nasal Strips Nasal passages collapse without extra support, UHVWULFWLQJDLUÀRZ Spring-like action gently holds nasal passages open to LPSURYHEUHDWKLQJ FLAIR Strips are proven to*: 9LK\JLS\UNISLLKPUN,07/ 4HRLIYLH[OPUNLHZPLY 9LK\JLMH[PN\L :OVY[LUYLJV]LY`[PTL *Abstracts available on our website. <:(-3(09 ^^^-SHPY:[YPWZJVT THOROUGHBRED TIMES July 21, 2012 31