BIOLOGY 211 Spring 2010 Suggested Problems Name KEY 2. An autosome in the four o’clock plant has the normal sequence of ABCD*EFGH (* is the centromere). Consider a heterozygote between this normal chromosome and an inversion chromosome that is AE*DCBFGH. A three-strand double crossover event occurs where one crossing over event occurs between C and D and the other crossing over event occurs between G and H. First, provide the chromosome sequence of the four meiotic products. Second, indicate whether each meiotic product is most likely viable (V) or not viable (N). First, correctly align the 2 homologues. Second, choose 3 chromatids (in this example, red, yellow, and blue) for the 3 strand double crossover. Third, trace the chromosomal segments by starting at one end of a chromatid. Normal ABCD*EFGH Inversion AE*DCBFGH D D D D 1 2 3 1 1 3 2 4 CC C C BB B B A A A A A BC D*E A AE *DCBF G H ABCD*EF GH HGF BC D*EFG H 1 3 2 4 E E E E FG H FG FG H H FG H 3 2 4 4 Dupli cation/ Deletio n (N) No t Vi abl e Inversion Viabl e (V) Normal Viabl e (V) Dupli cation/ Deletio n (N) No t Vi abl e