Are the diagnosis, diagnosis, and classification really necessary in psychiatry? psychiatry? Classification, nosology in psychiatry What is „normal” normal” or „pathological” pathological” human behaviour Can the „pathological” pathological”, the diagnosis be just a label or stigma? (social (social deviancy model) model) - / see antipsychiatry/ antipsychiatry/ Sandor Fekete Dept.of Psychiatry, Psychiatry, University of Pecs http:// psychiatry.pote.hu http://psychiatry.pote.hu The Fundamental Purpose of Diagnosis and Classification The purpose of diagnosis and classification is to isolate a group of discrete disease entities, entities, each of which is characterized by a distinct pathophysiology and/ and/or etiology. etiology. Ideally, Ideally, all diseases in medicine would be defined in terms of etiology. etiology. For most illnesses, illnesses, however, however, we do not know or understand exactly the specific etiology For most diseases, diseases, however, however, our understanding is at the level of pathophysiology rather than etiology. etiology. Most of the disorders or diseases diagnosed in psychiatry are syndromes: syndromes: collections of symptoms that tend to occur together. Purposes of Diagnosis in Psychiatry Diagnosis helps to simplify our thinking and reduce the complexity of clinical Psychiatric diagnoses facilitate communicacommunication between clinicians. clinicians. Diagnoses help to predict the outcome of the disorder Diagnoses are often used to decide on an appropriate treatment. treatment. Diagnosis are used to assist in the search for pathophysiology and etiology symptoms, symptoms, outcome, outcome, family clustering are different in these disorders/ disorders/syndroms also the biological background, background, specific responses in treatment Diagnosis, Diagnosis, classification in psychiatry Psychiatry tries consistently and comprehensively formalize the diagnostic processes for the disorders within its domain. domain. This precision and structure are particularly important in psychiatry because it lacks recognized etiologies for many disorders and lack specific laboratory diagnostic tests as well. well. diagnosis relies largely on the patient’ patient’s presenting symptoms and history. history. Without such structure, structure, the diagnostic process could become confused and fuzzy. fuzzy. Other Purposes of Diagnosis Diagnoses are used to monitor treatment and to make decisions about reimbursement Diagnoses are used by attorneys in malpractice suits and in other litigation. litigation. Diagnoses are used by health care epidemiologists to determine the incidence and prevalence of various diseases throughout the world. world. Diagnoses are used to make decisions about insurance coverage. coverage. fMRI – Anterior Cingula Cingular Cortex (ACC) DSM IV APA (1994) classifies mental disorders DSM IV APA (1994) classifies mental disorders The American Psychiatric Association has formulated a manual that summarizes all the diagnoses used in psychiatry, psychiatry, specfies the symptoms that must be present to make a given diagnosis and organizes these diagtnosis together into a classification system - Diagn. Diagn. And Statist Manual for mental Disorders (DSM) DSMDSM-IV is largely descriptive and atheoretical DSMDSM-IV makes use of a novel multiaxical system for recording diagnoses - (characterizing patients in multiple ways - evaluating all aspects of patient’ patient’s health and social background The five axes on which information should be recorded are as follows: follows: Paralelly - the ICD system international, international, WHO supported, supported, rather used in Europe - ICD10 Diagnostic criteria for Dysthymic Disorder - not multiaxial system - more formal diagnostic categories - list certain categories prefered by one or another national school. school. - More for statistical reasons Depressed mood - for at least 2 years - the mild, mild, chronic depression, depression, low mood, mood, anhedonia Presence of two (or more) of the following: following: (1) poor appetite or overeating (2) insomnia or hypersomnia (3) low energy or fatigue (4) low selfself-esteem (5) poor concentration or making decisions (6) feeling of hopelessness Symptomless periods less than two months No major depressive, depressive, no manic episode, episode, not other psychotic conditions Distress or impairment in social, social, occupational functioning Axis I is for the major clinical syndromes. syndromes. Axis II is for specific developmental disorders (for children and adolescents and, and, in some cases, cases, for adults), adults), and personality disorders (for adults, adults, and occasionally for children and adolescents). adolescents). Axis III is for physical disorders or conditions that the clinican considers potentially relevant to understanding or management of the patient. patient. Axis IV, IV, may be used to record the degree of severity of psychosocial stressors that the clinician considers significant in precipititating or exacerbating, exacerbating, the patient’ patient’s disorder. disorder. Axis V may be used to record the clinican’ clinican’s judgment regarding the highest level of adaptive functioning demonstrated by the patient during the past year. year. Axis I: Clinical Disorders and Other Conditions That May Be a Focus of Clinical Attention - Disorders usually first diagnosed in infancy, infancy, childhood, childhood, or adolescence - Delirium, Delirium, dementia, dementia, and amnestic and other cognitive disorders - Mental disorders due to a general medical condition - SubstanceSubstance-related disorders - Schizophrenia and other psychotic disorders - Mood disorders - Anxiety disorders Axis I: Clinical Disorders and Other Conditions That May Be a Focus of Clinical Attention - Somatoform disorders - Factitious disorders - Dissociative disorders - Sexual and gender identity disorders - Eating disorders - Sleep disorders - ImpulseImpulse-control disorders not elsewhere classified - Adjustment disorders - Other conditions that may be a focus of clinical attention Personality: a repertoire of coping devices or defenses that allows us to maintain an equilibrium between our internal drives and the world around us Personality traits: results of development that has been influenced by culture and society by the childchild-rearing practices of the family by genetically determined temperamental factors Personality disorders : the personality traits are inflexible and madaptive, madaptive, causing significant impairment in social or occupational functioning and/orsubjective and/orsubjective distress Axis IV: Psychosocial and Environmental Problems Problems with primary support group Problems related to the social environment Educational problems Occupational problems Housing problems Economic problems Problems with access to health care services Problems related to interaction with the legal system/ system/crime Other psychosocial and environmental problems Axis II: Personality Disorders and Mental Retardation Paranoid personality disorder Schizoid personality disorder Schizotypal personality disorder Antisocial personality disorder Borderline personality disorder Histrionic personality disorder Narcissistic personality disorder A B Avoidant personality disorder Dependent personality disorder C ObsessiveObsessive-compulsive personality disorder Mental retardation Pathological personality structures NEUROTIC: integrated identity highhigh-level defensive operations (repression) maintained reality testing BORDERLINE: identity diffusion primitive defensive operations maintained reality testing PSYCHOTIC: diffusion or lack of integration of identity primitive defensive operations (depersonalization) (denial) impaired reality testing Advantages and Disadvantages of the DSM 28III/IV 28III/IV Approach I. DSM IV substantially improved the reliability of diagnosis. diagnosis. Reliability, Reliability, a biometric concept, concept, refers to the ability of two observers to agree on what they see. see. The DSM IV approach has clarified the diagnostic process and facilitated history taking. taking. DSM IV also clarified and facilitated the process of differenctial diagnosis. diagnosis. Advantages and Disadvantages of the DSM IV Approach II. Comparison of BNOBNO-10 and DSMDSM-IV criteria BNOBNO-10 DSMDSM-IV DSM IV may sacrifice validity for reliability. reliability. Whereas reliability refers to the capacity of individuals to agree on what they see, see, validity refers to the capacirty to make useful predictions. predictions. origin European North American Main purpose Statistics Research, Research, clinical In particular, particular, the validity of a medical diagnostic system refers to its ability to predict prognosis and outcome, outcome, response to treatment, treatment, and ultimately etiology. etiology. axis NonNon-multiaxial Multiaxial Empirical basis moderate Strong categories Not very exact Quite clear, clear, some categories are arbitrary The increased precision sometimes gives clinicans and researchers a false sense of certainty about what they are doing. doing. BPRS - Bief Psychiatrc Rating Scale