Chapter 36: pp. 665 - 678 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 10th Edition Sylvia S. Mader Body Fluid Regulation & Excretory Systems BIOLOGY © Georgette Douwma/Photo Researchers, Inc. PowerPoint® Lecture Slides are prepared by Dr. Isaac Barjis, Biology Instructor Copyright © The McGraw Hill Companies Inc. Permission required for reproduction or display 1 2 • 2.D.2: Homeostatic mechanisms reflect both common ancestry and divergence due to adaptation in different environments. (36.1) • 2.D.3: Biological systems are affected by disruptions to their dynamic homeostasis. (36.2) • 4.B.2: Cooperative interactions within organisms promote efficiency in the use of energy and matter. (36.2) 3 Nitrogenous Waste Products • Ammonia (N2 waste) is the byproduct of catabolizing amino acids. Toxic to most animals. • Aquatic animals excrete ammonia directly. • Terrestrial animals must convert ammonia to urea or uric acid. • Urea needs lots of water per unit of nitrogen. • Mammals and amphibians • Uric acid requires much less water per unit of nitrogen excreted. • Reptiles, birds, and arthropods • Can live in arid environment. 4 Nitrogenous Wastes Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. proteins amino acids NH2 most fishes and other aquatic animals adult amphibians, sharks, and mammals Insects, birds, and reptiles ammonia urea uric acid O H N O H H2N C HN NH2 C H C N C O C H water needed to excrete energy needed to produce C N N H H O 5 Body Fluid Regulation • An excretory system regulate body fluid concentrations and is dependent on conc. of minerals (sodium, potassium…) • Obtain water by ingesting (food, drink) or metabolism. • Osmoregulation- maintaining proper water levels and ion conc. 6 Aquatic Animals • Bony Fishes • Marine bony fishes • Body fluids hypotonic to sea water, so they lose water through gills. • Must constantly drink to compensate. • Freshwater bony fishes have opposite problem • Body fluids hypertonic to fresh water, so they gain water through gills. • Eliminate excess water through copious urine. 7 Body Fluid Regulation in Bony Fishes Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. passive loss of water through gills drinks seawater salts actively excreted by gills scanty amount of isotonic urine contains some salts a. Marine bony fish passive gain of water through gills does not drink salts actively taken up by gills b. Freshwater bony fish large amounts of hypotonic urine contain few salts 8 Osmoregulation in a Shark Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Blood is isotonic to seawater. No need to osmoregulate. © Digital Vision Ltd 9 Terrestrial Animals • Terrestrial animals lose water through excretion and respiration. • Must drink water to make up for loss. • The environment the animal lives in dictates the method of osmoregulation. • i.e. Desert animals have a different system due to inadequate water supply to replenish water loss through urine. 10 Adaptations of a Kangaroo Rat to a Dry Environment Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Exhaled air is cooled and dried in long convoluted air passages. Animal fur prevents evaporative loss of water at skin. Urine is the most hypertonic known among animals. Fecal pellets are dry. Oxidation of food results in metabolic water. © Bob Calhoun/Bruce Coleman, Inc. 11 Adaptations of Marine Birds to a High Salt Environment Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. salt solution exits here salt solution runs down beak here © Eric Hosking/Photo Researchers, Inc. Human Urinary System • Functions to filter the blood & rid the body of waste, also homeostasis. • Composed of bladder, ureters, urethra, & kidneys, but works closely w/ circ. system. Anatomy of Urinary System 1. 2. 3. The ureters carry urine (excess water, waste, and excess ions) to the bladder. The bladder is a muscular bag that stores urine to expel. The urethra is a tube that takes waste out of the body. Anatomy of Urinary System 4. Kidneys- composed of the renal cortex, renal pelvis, and renal medulla. Supplied by the renal artery & blood exits via the renal vein. a. Nephrons- unit of the kidney; tiny filters 15 Macroscopic & Microscopic Anatomy of the Kidney Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. nephrons renal pelvis renal cortex renal medulla collecting duct ureter renal artery and vein a. Gross anatomy renal pyramid in renal medulla renal pelvis b. Two nephrons b. Blood flows into glomerulus (bed of capillaries); particles in the blood (glucose, salt, vitamins, waste, AAs) flow into Bowman’s capsule, which becomes loop of Henle. RLO: The Anatomy of the Kidneys c. Water, ions, & glucose are reabsorbed into the capillaries surrounding the loop, waste remains in tubules and is urine. 18 Processes in Urine Formation Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. glomerular capsule H2O Glomerular Filtration Water, salts, nutrient molecules, and waste molecules move from the glomerulus to the inside of the glomerular capsule. These small molecules are called the glomerular filtrate. urea glucose amino acids uric acid salts proximal convoluted tubule Tubular Reabsorption Nutrient and salt molecules are actively reabsorbed from the convoluted tubules into the peritubular capillary network, and water flows passively. glomerulus efferent arteriole Tubular Secretion Certain molecules (e.g., H+ and penicillin) are actively secreted from the peritubular capillary network into the convoluted tubules. afferent arteriole distal convoluted tubule renal artery renal vein venule collecting duct peritubular capillary network loop of the nephron H2O urea uric acid salts NH4+ creatinine 19 Reabsorption of Salt and Water Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. C1- Na+ Increasing solute concentration in renal medulla H2O Renal cortex Outer medulla ascending limb Na+ H2O H2O C1- descending limb Urea H2O H2O Inner medulla loop of the nephron collecting duct 20 Urine Formation and Homeostasis • Important to excrete water, but maintain homeostasis at the same time. • Water and salt are reabsorped in the loop of the nephron. • Antidiuretic hormone (ADH) • Released by the posterior lobe of the pituitary • ↑ ADH, ↑ water reabsorption. • Renal Physiology 21 The Renin-Angiotensin-Aldosterone System Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. liver kidneys adrenal cortex secrete renin blood vessel stimulates secretes secretes speeds angiotensin I angiotensin II angiotensinogen aldosterone Facts 1. 2. 3. Important to remove urea & ammoniatoxic- jaundice. Kidneys regulate pH, by regulating osmotic pressure Excess glucose is toxic- diabetes.