Pig Dissection #1 Fetal Development And the Umbilical Cord Producers of Shelled Eggs • Bird Egg? • Reptile Egg? • Monotreme Egg? Shelled egg structures • • • • • Germinal spot = “egg” Yolk = fat; energy White (albumen) = protein; structure Shell Air space Shelled Egg Membranes • Chorion – thin membrane that presses close to the shell; creates air space; allows gas exchange • Yolk sac – engulfs yolk; food source • Allantois – storage sac for waste; allows gas exchange • Amniotic sac – contains amniotic fluid; cushion, moisten, shock absorber Human embryos • Develop all shelled egg membranes • Some take on new roles – ie. Help develop the placenta Human embryo amnion and yolk sac Other embryonic evolutionary “left-overs”? • Fetal tail • Fetal gill arches Placenta development • Fertilization occurs where? • Fallopian tube • Mitosis begins; 5 – 10 days later embryo arrives in uterus • Chorion begins to embedd in endometrium lining of uterus Human Female Reproductive Anatomy Embedding Embryo Placental Formation • Chorion begins to grow villi into uterine lining • Allantoic and yolk sac blood vessels begin to form umbilical cord • Chorion begins to release HCG – human chorionic gonadotropin hormone that maintains the developing placenta in the uterus • Effect on the uterine lining? • Missed period • HCG detected in pregnancy urine test • Later, placenta makes its own hormones to maintain itself (progesterone) Fetal Development Late Term Fetus Amniocentesis • • Needle used to sample amniotic fluid for diagnostic purposes Done at 14 – 16 weeks Chorionic Villi Sampling • CVS • Sample of placenta taken for diagnostic purposes • Done at about 10 weeks Umbilical Cord • • • • • • Forms partially from old allantoic and yolk stalks – using their blood vessels Connects fetal blood to the placenta Placenta contains maternal blood Cord – contains 2 umbilical arteries and 1 umbilical vein Arteries – **carry blood away from a reference point** Reference point: fetus **Usually carry oxygenated blood** Exception: these 2 umbilical arteries carry deoxygenated blood from baby to mom Veins - **carry blood toward a reference point** Reference point: still fetus **Usually carry deoxygenated blood** Exception: the umbilical vein carries oxgenated blood from mom to baby Fetal Circulation Oxygenated blood Deoxygenated blood Placenta • Umbilical arteries branch into small capillaries at the placenta • Diffusion occurs across capillary walls from baby to mom • What diffuses? • CO2, waste (urea) • Mom’s lungs and kidneys excrete Placental Detail Placental Detail Placental Blood Exchange? • • • • Does fetal blood mix with maternal blood? NO!! Why not? Separated by capillary wall Only diffusion occurs Placental Detail • What diffuses from mom’s blood to baby? • Food, minerals, vitamins, O2, antibodies, water, drugs, cigarette chemicals • Carried back to fetus by umbilical vein • Blood enters the fetal liver prior to the fetal heart and general circulation • Ideas why? • Detoxify and store glucose Cross Section View of the Umbilical Cord – “Live” Fetus Cross Section View of the Umbilical Cord – “Dead” latex injected fetus Human Female Reproductive Anatomy Animal bihorned uterus • Uterus split into 2 parts (horns) • Allows for multiple embryos