Pharmacotherapy XII - Psychiatric
PHAR4262
FALL 2011 Syllabus
Course Title/Number: Pharmacotherapy XII – Psychiatric (PHAR 4262)
Team Leader: (Office hours by appointment)
Monica Mathys, Pharm.D., BCPP, CGP
Dallas VA Campus
Email: monica.mathys@ttuhsc.edu
Phone: (972) 800-6842
Team Members: (Office hours by appointment)
Quentin Smith, Ph.D.
Amarillo Campus
Email: quentin.smith@ttuhsc.edu
Phone: (806) 356-4750 x250
Rebecca Sleeper-Irons, Pharm.D., BCPS
Lubbock Campus
Email: rebecca.sleeper@ttuhsc.edu
Phone: (806) 743-4200 x223
Pam Ochoa, Pharm.D.
Abilene Campus
Email: pamella.ochoa@ttuhsc.edu
Phone: 325-676-7948 x 244
Textbook/Course Materials:
1. DiPiro, et al. (eds.), Pharmacotherapy, A Pathophysiologic Approach, 7th
ed., McGraw-Hill, New York, NY, 2008.
2. Hardman, et al. (eds.), Goodman & Gilman's The Pharmacological
Basis of Therapeutics, 11th ed., McGraw-Hill, New York, NY, 2006.
Suggested Textbook for Additional Information:
1. Stahl. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and
Practical Applications, 3rd ed., Cambridge University Press, New York, NY,
2008.
Prerequisites or Concurrent Enrollment:
P3 student in good standing at TTUHSC SOP.
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This course is designed with the assumption that the Doctoral Candidates have
no previous understanding of Psychiatric Disorders.
Catalog Description:
Pathophysiology and clinical presentation of common psychiatric diseases;
chemistry, pharmacology and toxicology of common therapeutic agents used to
treat psychiatric diseases; therapeutic management of patients.
Course Mission and Purpose:
Pharmacy 4262 will provide the doctoral candidates with the basic skills required
to formulate rational therapeutic regimens for the treatment of common
psychiatric disorders. The course will demonstrate, through a problem-based
approach, the necessary steps that must be considered when initiating,
modifying, and monitoring the drug therapy of a patient with psychiatric disorders.
Ultimately, the Candidate’s development of patient care plans will seek to
integrate the basic pathophysiology, pharmacology and therapeutics presented
during this course.
Course Objectives and Outcomes:
1. Explain neurologic and psychiatric anatomy and function.
TTUHSC SOP Top 7Ability Set:
 Application of basic science principles to the practice of pharmacy
2. Differentiate psychiatric disorders in terms of incidence, epidemiology,
etiology, pathophysiology, clinical presentation and therapy.
TTUHSC SOP Top 7 Ability Sets:
 Application of basic science principles to the practice of pharmacy
 Providing pharmaceutical care to individual patients
3. Identify pharmacotherapeutic goals and recommend drugs to treat psychiatric
disorders in terms of mechanism of action, pharmacokinetics, therapeutic
efficacy, adverse effects, drug interactions, dosing and administration, and
cost of treatment.
TTUHSC SOP Top 7 Ability Sets:
 Application of basic science principles to the practice of pharmacy
 Providing pharmaceutical care to individual patients
 Problem solving and scientific inquiry
4. Evaluate appropriate dose/regimens and counsel a patient with a psychiatric
disorder.
TTUHSC SOP Top 7 Ability Sets:
 Providing pharmaceutical care to individual patients
5. Understand the bias towards patients with psychiatric problems.
TTUHSC SOP Top 7 Ability Sets:
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
Personal judgment (ethical, moral, and practical)
Teaching Methods:
The course will consist of lectures and case-based studies. Most lectures will be
presented live. The few lectures not presented live will be recorded and
available for students to view on WebCT in a timely manner. Three patient cases
will be given throughout the course. Students are expected to review the cases
and complete the questions outside of scheduled lectures.
Attendance:
Students are expected to attend all lectures. In the event of an unavoidable
absence, students should make an effort to obtain notes from classmates, as
lecture handouts may not incorporate all the material that may appear on exams.
Patient Cases (15% of final grade):
Three patient cases will be given throughout the course to help reinforce lecture
materials. Students may work by themselves or in groups of 2 or 3 to complete
the cases. Once student groups are formed for Case 1, students must stay in
the same groups for cases 2-3. If a student chooses to work alone for case 1,
he/she must continue to work alone for case 2-3. On the due dates, one student
from each group is expected to e-mail the case answers to Dr. Mathys by 5pm.
Names of all students who helped with the assignment should be included on the
report. If a particular student did not help with the assignment, DO NOT
INCLUDE HIS/HER NAME.
Group members are not to share answers with students outside of their own
group. Any students found cheating or plagiarizing an assignment will receive a
zero for the case.
Overview of Examination Schedule:
Exam #1: Friday, October 28, 2011 from 8:30am-9:50am
AMSPAC 1120, ABSOP 2300, HSC 1C124, DLSPSW 450
Exam #2: Friday, November 18, 2011 from 8:30am-9:50am
AMSPAC 1120, ABSOP 2300, HSC 1C124, DLSPSW 450
Final exam: Tuesday, December 13, 2011 from 1pm-2:20pm
Room locations TBA
Exams (85% of final grade):
Three exams will be given during the course. The doctoral candidate should note
that examination material is based on retention of knowledge from all course
material presented up until the time of each exam. The minimum passing score
for each examination is 70%.
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Exam 1: Will cover material from Pathophysiology of Psychotic Disorders (10/13)
through Bipolar Pharmacotherapy (10/25). This exam will be worth 80 points.
Exam 2: Will cover material from Pathophysiology of Depression (10/31) through
GAD Pharmacotherapy (11/15). This exam will be worth 100 points.
Final Exam: Will cover material from PTSD/Panic Pharmacotherapy (11/21)
through ADHD Pharmacotherapy (12/8). This exam will be worth 90 points.
% of Total Grade
85% (270 points)
15% (45 points)
Exam 1
Item
Dates
Friday, October 28
Exam 2
Friday, November 18
Final Exam
Case 1 Schizophrenia
Tuesday, December 13
Due October 25
Case 2 Mood Disorder
Due November 14
Case 3
Substance/Anxiety
Due December 8
100% (315 points)
Exam Policy:
1. Prompt attendance at specified exam times is required. Students will not be
admitted after the first student to complete the exam has left a testing room.
2. Except under exceptional circumstances, students should not leave the
exam room any time during the exam. Students should attend to personal
needs before being seated.
3. If required by the course team or faculty proctor, students must comply with
assigned seating instructions throughout the exam period.
4. Students must store all personal items as follows:
 Students are strongly encouraged to lock all personal items in their
locker or in the trunks of their cars.
 Student back packs, book bags, computer bags, and the like must be
placed along the sides, front, or back of the room. No such items will be
allowed at the students’ desks.
 Purses may be placed at the side of the room near the student’s desk;
but purses will not be allowed at the student’s desk or near their feet.
 No drinks or snacks of any type may be at the desk.
 Students must remove hats, caps, and all headwear. Headwear of a
religious nature is permitted.
 All coats and, jackets (including lab jackets) should be placed on the
sides of the room or returned to the student’s lockers. No loose clothing
is allowed at the desk.
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5. Nothing with an on off switch is permissible at the student’s desk or on their
person.
6. No PDAs, computers (unless expressly approved for a specific exam),
IPODs, cell phones, etc. are allowed at the students desk or on their person.
Cell phones for medical needs can be left at student services.
7. Students are not allowed to bring paper. If scratch paper is needed, the
exam proctor will furnish it. Tissue packs will be furnished by student
services.
8. Student Questions: Proctors will not answer any questions, related to
content. If exam errors are found, the team leader will determine how to
correct the error (or omit the question) after all exams are completed. In the
rare event that an exam is missing a page or a computer is malfunctioning,
the proctor may answer the question and resolve the problem.
9. Students should not disrupt the exam environment in any manner including
but not limited to talking, and making unnecessary noises. In general silence
should be observed during the exam period.
10. Faculty will announce the exact the time limits to be followed on their
respective campus. Students shall hand their completed paper exam back to
the proctor.
11. Students must return all exam materials such as a paper exam, scantron
sheet, and all scratch paper.
12. The faculty proctor will initiate an academic misconduct investigation, for all
involved students who violate Exam Procedures.
Grading:
Grading will be conducted by the Psychiatric Pharmacotherapy team members.
Students will have the opportunity to appeal to the team leader regarding your
examination grade within 2 working days from the date results are announced.
The team encourages students to review their missed exam questions. Any
student who wishes to review through their exam after grades are posted will
need to schedule a phone or face to face appointment with the team leader.
Second Chance Policy:
The School’s Second Chance Policy applies to this course. A doctor of
pharmacy student, if eligible, may take a single comprehensive examination to
demonstrate competency in that course providing the following:
 The student has passed 50% or more of the major assessments in that
course
 The student has earned a final grade of 66-69% in the course, and
 The student has not exceeded the number of second chance attempts as
outlined below.
A student may invoke the Second Chance Policy in a maximum of two courses
per semester, and no more than four times total in his/her career at the School.
No student may invoke the second chance exam for the same course twice.
The second chance assessment shall occur in a timely fashion with the timing
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at the discretion of the course team. If the student passes the second chance
exam, she/he will receive 70% as final grade.
Candidate Disability:
Any student who, because of a disability, may require special arrangements in
order to meet course requirements should contact the Team Leader within 1
week of the beginning of this course to make the necessary accommodations.
Ethical Standards:
The ethics standards for the School of Pharmacy and the APhA Code of Ethics
are in effect for all components of this course. This course will adhere to the
TTUHSC Student Handbook: Code of Professional and Academic Misconduct.
Candidates found to be in violation of ethical standards will receive zero (0)
points for the course in question and will be reported to the Dean’s Office and the
Credentialling and Student Affairs Committees of the School of Pharmacy.
Further information may be obtained from the SOP Student Handbook or the
TTUHSC Student Handbook.
Missed Examination Policy:
Make-ups for missed examinations with a valid excused absence will be provided
only at the discretion of the course team leader after consultation with the
teaching team members. Candidates that miss an examination should contact
the team leader or another team member either in advance or as soon as
possible after the missed examination. Students arriving late to an exam after the
first student has left the testing room are considered to have missed the exam. It
is strongly recommended that a physician's note and/or other supporting
documents be provided in such an absence. Each case will be reviewed on an
individual basis. The decision of the course coordinator will be final.
Candidate Inquiries:
Questions or comments regarding the course should be directed to the Team
Leader or other members of the Psychiatric Pharmacotherapy Team via email.
Two working days may be required for email responses to candidate questions.
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Course Schedule: Lectures Mon, Tue, Thur, Fri at 2:30pm-3:20pm
AMSOP 335, ABSOP 2100, HSC 1C111 TLK, DLSPSW 450, DLSPVA 200
Lecture Outline
Psychiatry Pharmacotherapy PHAR 4262
Day
Thur
Date
October 13
Fri
Mon
Tue
Thur
Fri
Mon
October 14
October 17
October 18
October 20
October 21
October 24
Tue
Thur
Fri
Mon
Tue
Thur
Fri
Mon
Tue
Thur
October 25
October 27
October 28
October 31
November 1
November 3
November 4
November 7
November 8
November 10
Fri
Mon
Tue
Thur
Fri
Mon
November 11
November 14
November 15
November 17
November 18
November 21
Tue
Mon
Tue
Thur
Fri
November 22
November 28
November 29
December 1
December 2
Mon
Tue
Thur
Fri
Tue
December 5
December 6
December 8
December 9
December 13
Lecture Topic
Psychotic Disorders
Pathophysiology
Antipsychotics Pharmacology
Antipsychotics Pharmacology
Schizophrenia Pharmacotherapy
Bipolar Pathophysiology
Mood Stabilizers Pharmacology
Schizophrenia Pharmacotherapy
and Introduction to MH
assessment
Bipolar Pharmacotherapy
Review Case 1/ Review for exam
EXAM 1 8:30am-9:50am
Depression Pathophysiology
Antidepressant Pharmacology
Antidepressant Pharmacology
Depression Pharmacotherapy
Depression Pharmacotherapy
Sleep Cycle and Physiology
Hypnotics Benzodiazepine
Pharmacology
Insomnia Pharmacotherapy
Anxiety Pathophysiology
GAD Pharmacotherapy
Review Case 2/Review for exam
Exam 2 8:30am-9:50am
PTSD/Panic/OCD
Pharmacotherapy
Substance Abuse
MJ/Opiate Dependence
Alcohol Dependence
Nicotine Dependence
Alcohol/Opiate/Nicotine
Pharmacotherapy
Cocaine/Stimulant Dependence
ADHD Pathophysiology
ADHD Pharmacotherapy
Review Case 3/Review for exam
Final Exam 1pm-2:20pm
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Lecturer
Smith
Smith
Smith
Mathys
Smith
Smith
Mathys
Mathys
Mathys
Smith
Smith
Smith
Mathys
Mathys
Smith
Smith
Mathys
Smith
Mathys
Mathys
Comments
Begin Case 1
Case 1 Due
Begin Case 2
Case 2 Due
Mathys
Smith
Smith
Smith
Smith
Smith
Smith
Smith
Mathys
Mathys
Begin Case 3
Case 3 Due