DataSafe Solutions FAQ ™ Why should I have a central storage space for my next-generation sequencing (NGS) data? What storage capacity is available with DataSafe Solutions? When a sequencer’s primary storage becomes full, sequence data needs to be transferred or deleted in order to continue sequencer use. Having a central storage device that is tolerant to disk failures is a best practice for storing data, and provides a level of data protection that desktop PCs, external hard drives, and USB flash drives do not provide. Additionally, a central storage space improves organization of data, and allows laboratories to tightly control access to sensitive data. Storage capacity can be configured to your particular needs and throughput of your lab. Typical capacity requirements range from 20 TB to 500 TB raw and are scalable. Why should I have a backup of my NGS data? Hardware malfunctions, damage, and theft, while not common, may result in permanent data loss and potentially high cost for a NGS lab. It is beneficial to have sequencing data replicated onto a separate physical device, on a schedule you control. What instruments are compatible with DataSafe Solutions? ™ ™ How do DataSafe Solutions devices present the data volumes? ™ Storage on DataSafe Solutions devices are typically presented as a single logical volume (single namespace) within system limits. Capacity can be expanded at a later time, within the single volume, within system limits. There are options for multiple storage volumes if required. ™ What file systems are DataSafe Solutions compatible with? ™ The file systems are NFS, CIFS, and SMB compatible, allowing connectivity with Windows and Linux systems. ® ® DataSafe Solutions are fully compatible with Linux and Windows -based systems, including most NGS, qPCR, mass spectrometry, and imaging instruments. At this time, our system integration step is only being carrying out with Ion Torrent sequencers, and any other instruments must be integrated by the customer. Your Thermo Fisher Scientific IT consultant can provide best-practice guidance for doing so. Who manufactures the DataSafe Solutions hardware? Are DataSafe Solutions storage or backup, or both? Redundant array of independent disks (RAID) is a technology that utilizes multiple disks in a single system to provide redundancy in cases when an individual disk fails. The RAID configuration on most DataSafe Solutions is customizable and the specific configuration can be set up based on your needs. For example, RAID 6 enables the system to tolerate up to two failed disks without incurring data loss. ™ ® ® ™ ™ DataSafe Solutions are configurable systems that are available in two major configurations. The single-device configuration provides networked storage. The dual-device configuration provides networked storage and backup. If your site already has a network-attached storage (NAS) device, in some cases, the single-device configuration may be able to be used as a backup to that existing system. ™ What type of hardware is provided by DataSafe Solutions? ™ DataSafe Solutions hardware is based on scale-out NAS that are designed and configured by the IT consultant based on the needs of your lab. Hard drives are RAID configured, and high availability (HA) options are available. ™ What operating system does DataSafe Solutions run on? ™ DataSafe Solutions are run on proprietary operating systems, which are optimized for storing and serving files. ™ ™ We have partnered with several major global storage IT manufacturers to provide efficient hardware for NGS lab environments. What is RAID, and why is it important? What RAID scheme is my DataSafe Solution? ™ ™ What safety precautions can be taken to protect access to my data? The DataSafe Solutions system will reside on your organization’s local area network (LAN). Firewalls and security precautions must be implemented by your organization. ™ Are DataSafe Solutions meant for long-term (>10 year) storage? ™ No, at this time, DataSafe Solutions does not provide a long-term archive or tape backup solution, but the system is compatible with systems that can provide archiving. ™ Is this solution HIPAA compatible? What are the transfer speeds to DataSafe Solutions devices? ™ Yes, your DataSafe Solution's hardware is networked on your intranet for authorized users only with user-specific or IP-specific permissions. ™ Can the capacity of DataSafe Solutions be expanded at a later time? ™ DataSafe Solutions are scalable and upgrades can be performed by the DataSafe Solutions team or your internal team. ™ ™ Can I search and retrieve a specific run report? Transfer speeds to the devices are dependent on the speed of your intranet. If a dual-device configuration is chosen, the transfer speeds between devices can be 1 GbE or 10 GbE, based on your needs. Do you provide a data recovery service, in cases of data loss? No, we can’t retrieve data from damaged hard drives and are not responsible for data loss. Yes, if your DataSafe Solution is integrated with Ion Torrent Sequencers. Do I need to host DataSafe Solutions in my local data center or server room? Can I search the DataSafe Solutions repository to look for samples with a specific mutation? No, the system does not provide tools for data mining. A server room is recommended, but not required. Alternatively, DataSafe Solutions can be deployed in mini-racks to fit in small spaces. The space allocated for the hardware component should have adequate HVAC and power source. Is this an indexing system, and can I query existing files? Can DataSafe Solutions be used to expand an existing NAS solution? ™ ™ ™ No, this is neither a laboratory information management system (LIMS) nor a data management system. What support is provided with DataSafe Solutions? ™ DataSafe Solutions come standard with 5-year, on-site support for hardware and software. In addition, we include 1 year of direct access to specialized IT consultants for integration support, network connectivity support, and data management support. The IT consultants are available remotely to walk you through the necessary steps to recover data if needed. IT consultant access can be extended beyond the first year through a service contract. ™ I’m in a regulated lab (CLIA, GxP, ISO, etc.); do you offer validation services? In the future we plan to offer an optional computer system validation. Where are DataSafe Solutions physically located? I’m not allowed to upload clinical data to cloudbased systems. ™ DataSafe Solutions are physical on-site storage at your institution. ™ Do you offer an off-site backup option? We offer some off-site solutions, including CloudSuite Digital Storage. Please inquire for more details. ™ ™ ™ DataSafe Solutions are standalone NAS, available in singledevice configuration (networked storage) or dual-device configurations (networked storage and backup). In some cases, DataSafe Solutions may be integrated as a backup to an existing NAS system. ™ ™ Do I have the option to connect to the cloud for additional backup? Presently, there isn’t connectivity built into CloudSuite Data Storage from Thermo Fisher Scientific, but a user’s IT department can tie the DataSafe Storage to cloud-based storage using their method of choice. ™ How much power do I need to run the system? Power requirements are dependent on the solution configured for you. How long will system integration take? The integration itself takes 2–4 days from the arrival of our IT consultant to your site. The integration can begin after your laboratory receives the hardware, the integration date has been scheduled, and your site has been prepared for installation. Who do I call for postintegration support? Your Thermo Fisher Scientific IT consultant is available to help with any questions or walk you through any data recovery needs, and is available both by email and phone. lifetechnologies.com/datasafe © 2015 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. Linux is a trademark of Torvalds, Linus. CO29824 0215