MCDB 1030 Plagues and Peoples Spring 2005 Date Lecture Jan. 11 Overview of Infectious Diseases Intro to the players Historical Ideas about Infectious Diseases Biological Macromolecules Bauman Ch. 3 Bauman Ch. 7, p. 199-212 Jan. 25 DNA Replication and Transcription Class cancelled Jan. 27 Translation Bauman Ch. 7, p. 212-216 Feb. 1 Mutations and Natural Selection Feb. 3 Bacteria Bauman Ch. 7, p. 221-236 “The Lethal Gift of Livestock”, Ch. 11 from Jared Diamond’s “Guns, Germs, and Steel” (e-reserve) Bauman Ch. 3 – p. 67-76 Bauman Ch. 11 – emphasize p. 314-316, scan the rest Bauman Ch. 6 – p. 167-189 Feb. 8 Viruses Feb. 10 Hour exam Covers through lecture on viruses Feb. 15 Infection/Virulence Bauman Ch. 14 Jan. 13 Jan. 18 Jan. 20 Special Notes Reading Bauman Ch. 1 Bauman Ch. 2 Homework Set 1 due Homework Set 2 due 1 Bauman Ch. 13, p. 378-397 Feb. 17 Field trip to the CAVE Feb. 22 Non-Specific host Defenses Bauman Ch. 15 Feb. 24 The Immune System Antibodies The Immune System – Cellmediated Immunity Bauman Ch. 16 Mar. 3 Anthrax Mar. 8 Plague Mar. 10 Mar.15 (SC) Mar. 17 Antibiotics and Antibiotic Resistance Field trip to Special Collections Influenza “Attacking Anthrax”, Scientific American, March 2002 (ereserve) “A Sure Killer Yields to Medicine”, Science 294, p. 1813-1814 (Chinook) Bauman Ch. 20, p. 580-581 “How a Mysterious Disease Laid Low Europe’s Masses” (ereserve) Bauman Ch. 10 Mar. 21-25 Mar. 29 Mar. 31 Spring Break AIDS AIDS Mar. 1 Bauman Ch. 16 Homework Set 3 due “Are We Ready for Pandemic Influenza?”, Science, 302, 15191522, 2003 (Chinook) “Disarming Flu Viruses”, Scientific American, Jan. 1999 (ereserve) Bauman Ch. 25, p. 718 – 724 “Improving HIV Therapy”, Scientific American, July 2003 (ereserve) “HIV/AIDS Treatment for Millions”, Science, vol 292, p. 221223 “How HIV Defeats the Immune System”, Scientific American, July 2003 (e-reserve) 2 Apr. 5 Vaccines Homework Set 4 due “Edible Vaccines”, Scientific American, Sept. 2000 Apr. 7 Hour exam Hour exam Covers lectures through AIDS Apr. 12 Bioterrorism Apr. 14 Plant pathogens Apr. 19 Apr. 21 Malaria and other MosquitoBorne Diseases Prions Apr. 28 Emerging Threats Bauman Ch. 26, p. 772-775 “Creatures of Our Own Making”, Science, vol. 298, 80-86, access through Chinook “Detecting Mad Cow Disease”, Scientific American, July, 2004 (e-reserve) Homework Set 5 due Wednesday, Final Exam May 4, 10:30 AM– 1 pm 3