Table 1. Listed below are common and trade names of select fungicides currently registered in the United States representing the major fungicide groups and chemistry within these groups (chemical group), plus the mobility, activity, and risk of resistance developing to these fungicides. Group Name (Abbreviation)1 Methyl benzimidazole carbamate (MBC) dicarboximide Chemical Group Common Name benzimidazole thiophanate-methyl dicarboximide imidazole 3 demethylation inhibitor (DMI) DMI iprodione vinclozolin triflumizole piperazine triforine 3 DMI triazole myclobutanil 3 DMI triazole tebuconazole 4 phenylamide (PA) phenylamide mefenoxam, 7 carboxamide oxathiin carboxin Apron XL, Ridomil Gold,Subdue Maxx Vitavax 9 anilinopyrimidine (AP) anilinopyrimidine cyprodinil Vangard 11 strobilurin azoxystrobin 11 quinone outside inhibitor (QoI) QoI strobilurin trifloxystrobin 11 QoI strobilurin pyraclostrobin Abound, Quadris, Heritage Flint, Gem, Compass Cabrio, Headline 12 phenylpyrrole (PP) phenylpyrrole fludioxonil 14 chlorophenyls quintozene 14 aromatic hydrocarbon (AH) AH Maxim, Medallion, Scholar PCNB, Blocker chloronitroben-zene dicloran Botran contact 14 AH triadiazole etridiazole Truban, Koban contact Group Code1 1 2 3 Example Trade Name Topsin M, Cleary’s 3336 Mobility Mode of Action of Fungicide xylem mobile Inhibits tubulin formation in mitosis, broad-spectrum Chipco 26GT, Rovral, Ronilan Procure, Terraguard Funginex, Saprol contact NADH cytochrome c reductase in lipid per-oxidation (Proposed), broad-spectrum Sterol biosynthesis inhibition, broadspectrum Sterol biosynthesis inhibition, narrowspectrum Sterol biosynthesis inhibition, broadspectrum Sterol biosynthesis inhibition, broadspectrum Inhibits RNA synthesis, active on oomycetes Eagle, Nova, Rally Folicur xylem mobile xylem mobile xylem mobile xylem mobile xylem mobile locally systemic locally systemic xylem mobile locally systemic locally systemic contact contact Risk of Resistance2 high medium to high medium medium medium medium high Inhibits respiration (MET2, succinate dehydrogenase), active on basidiomycetes Methionine biosynthesis and hydrolytic enzymes, active on Botrytis, Monilinia, Venturia Inhibits respiration (MET-III, cytochrome bc1), broad-spectrum Inhibits respiration, broad-spectrum medium Inhibits respiration, broad-spectrum high Disrupts membrane integrity, broadspectrum low to medium Thought to act on lipids, active on basidiomycetes and some ascomycetes Acts on Botrytis,Monilinia, Rhizopus and Sclerotinia Curative and preventative control of soil borne diseases, especially oomycetes. low to medium medium high high low to medium low to medium 15 cinnamic acid cinnamic acid dimethomorph Acrobat 17 hydroxyanilide hydroxyanilide fenhexamid Elevate, Decree 18 Antibiotic streptomyces streptomycin 19 polyoxin polyoxin polyoxin D Agri-Mycin, AgriStep Endorse 21 (P) 21 (P) host plant defense inducers (SAR) SAR benzothiadiazole harpin Ea protein acibenzolar-Smethyl harpin Messenger M (33) M (33) M multi-site activity phosphonate fosetyl-aluminum Aliette multi-site activity phosphonate phosphorous acid Phostrol, ProPhyt multi-site activity inorganics copper Kocide, Champ M multi-site activity inorganics sulfur M multi-site activity dithiocarbamate mancozeb, maneb Microthiol Disperss, MicroSulf Mancozeb, Maneb contact M multi-site activity dithiocarbamate Thiram contact M multi-site activity chloroalkythios dimethyldithiocarbamate captan Captan contact M multi-site activity chloronitrile chlorothalonil contact M (29) U (27) U (28) multi-site activity phenylpyridin-amine fluazinam Bravo, Daconil2787 Omega unknown. cymoxanil Curzate M-8 unknown cyano-acetamide oxime carbamate propamocarb Banol, Previcur F biofungicide fungal Primastop biofungicide fungal Gliocladium catenulatum strain J1446 Aspergillus flavus AF-36 locally systemic locally systemic xylem mobile N/A AF-36 N/A biofungicide fungal Contans N/A biofungicide bacterial Serenade contact Coniothyrium minitans strain CON/M/91-08 Bacillus subtilis Actigard locally systemic locally systemic xylem mobile xylem mobile amphimobile signal xylem mobile amphimobile amphimobile contact contact Thought to act on cell wall synthesis in certain oomycetes Sterol biosynthesis inhibitor, Botrytis, Monilina, Sclerotinia Single-site, bactericide low to medium low to medium high Single-site, inhibits chitin synthetase, acts on some fungi. Activates plant’s systemic acquired resistance (SAR), broad-spectrum Elicits a hypersensitive response in plants, broad-spectrum medium Inhibits oxidative phosphororylation in oomycetes Inhibits oxidative phosphororylation in oomycetes Disrupts function of enzymes and energy transport systems, integrity of membranes Inhibits electron movement, thus interferes with cellular respiration low Reacts with protein SH groups, broadspectrum Reacts with protein SH groups, broadspectrum seed treatment Combines with thiols (SH groups) broadspectrum Acts on fungal respiration via thiol, broad-spectrum Uncouples oxidative phosphorylation, broad-spectrum Short residual, acts on oomycetes low low low low low low low low low low low to medium Active on oomycetes low to medium Competitive exclusion. Competitive colonizer of soil media unknown Competitive exclusion. Competitive colonizer of cotton flowers. Displaces other A. flavus in the soil surface. Pathogenic. Colonizes and kills sclerotia of Sclerotinia spp. unknown Induced resistance. Active on powdery unknown unknown strain QST 713 1 biofungicide biofungicide aldehyde oil cinnamaldehyde mineral oil biofungicide oil plant essential oil biofungicide mineral products biofungicide mineral products Biofungicide clay potassium bicarbonate monopotassium phosphate kaolin Vertigo JMS Stylet-oil, SunSpray UltraFine Sporan Armicarb 100, Kaligreen Nutrol Surround and induced resistance contact contact contact contact contact and SAR contact mildew, downy mildew, Phytophthora, Alternaria and Botrytis Biofungicide, algacide Destroys cell walls, interferes with fungus attaching to plant unknown unknown Destroys cell walls, interferes with fungus attaching to plant Upsets potassium ion balance in powdery mildew fungal cells, cell wall collapses SAR, plasmolysis of conidia, destruction of conidiophores, antisporulant Forms physical barrier to organisms, suppresses powdery mildew unknown unknown unknown unknown Group codes, names, and abbreviations used by FRAC and by the EPA Office of Pesticide Programs as part of the pesticide classification system developed for pesticide resistance management labeling (www.epa.gov/opppmsd1/PR_Notices/pr2001-5.pdf). Fungicide groups are excluded that do not have a product registered in the USA. FRAC code is listed in parentheses under the EPA Group code when the codes differ. Neither system includes biofungicides. 2 Risk of resistance is considered high when mode of resistance is known (or suspected) to be qualitative or some pathogens have already developed resistance within a few years under commercial use, medium when mode of resistance is quantitative, and low when the fungicide has multi-site activity. Entries in this column were assigned by FRAC (www.frac.info/publications.html). Labels for fungicides registered in the USA are accessible at www.epa.gov/pesticides/pestlabels/ and www.cdms.net/manuf/manuf.asp.