Ibon Garitaonandia, PhD 1
IBON GARITAONANDIA, Ph.D.
Center for Regenerative Medicine
The Scripps Research Institute
10550 North Torrey Pines Road
La Jolla, CA 92037
Tel: 858-784-7753
Fax: 858-784-7211
ibong@scripps.edu
2148 Fenton Pkwy #208
San Diego, CA 92108
Tel: 619 684 1641
ibon022479@yahoo.com
EDUCATION
Center for Regenerative Medicine, Scripps Research Institute, La Jolla, CA
California Institute for Regenerative Medicine (CIRM) Postdoctoral Fellow, 2009 – present
O’Keeffe Foundation Postdoctoral Fellow, 2008 – 2009
Research Advisor: Dr. Jeanne F. Loring
University of Phoenix, San Diego, CA
Master of Business Administration candidate, January 2010 – expected June 2011
University of Florida, Gainesville, FL
Doctor of Philosophy in Biochemistry, December 2007
Graduate Research Advisor: Dr. Thomas J. Lyons
University of the Basque Country, San Sebastián, Spain
Bachelor of Science in Chemistry, July 2002
RESEARCH EXPERIENCE
Center for Regenerative Medicine, Scripps Research Institute, 2008- present
Studied the effects of culture methods on the genetic stability and phenotypic properties of
human embryonic stem cells (hESCs). Generated induced pluripotent stem (IPS) cells from
Amyotrophic Lateral Sclerosis (ALS) patients and differentiated the IPS cells into motor
neurons.
Department of Neurobiology, Scripps Research Institute, 2008.
Studied the involvement of mitochondrial proteins in the differentiation of mouse and rat neural
progenitor cells into neurons.
Department of Chemistry, University of Florida, 2002 - 2007.
Studied the mechanism of signal transduction of the human adiponectin receptors in the
Saccharomyces cerevisiae and discovered a new human adiponectin receptor, PAQR3. Designed
and patented a high throughput β-galactosidase assay that allows for the detection of inhibitors
and activators of adiponectin receptors.
Ibon Garitaonandia, PhD 2
TEACHING EXPERIENCE
Center for Regenerative Medicine, Scripps Research Institute, 2008 - present: Served as an
instructor in the NIH and CIRM sponsored Human Embryonic Stem Cell Comprehensive
Training Course and taught transfection of hESCs and teratoma assays.
Department of Chemistry, University of Florida, 2002 - 2007: Served as a teaching assistant in
general chemistry, organic chemistry, biochemistry, molecular biology, and bioorganic
chemistry.
PUBLICATIONS
Brian R. Kupchak, Ibon Garitaonandia, Jessica L. Smith, Thomas J. Lyons “Identification of
small molecule and proteinaceous antagonists of human PAQR receptors”. Biochemistry
2009;48(24):5504-5506.
Ibon Garitaonandia, Jessica L. Smith, Brian R. Kupchak, Thomas J. Lyons “Adiponectin
identified as an agonist for PAQR3/RKTG using a yeast-based assay system”. Journal of
Receptors and Signal Transduction 2009;29(1):67-73.
Nancy Y. Villa, Brian R. Kupchak, Ibon Garitaonandia, Jessica L. Smith, Emilio Alonso,
Charlene Alford, Ashley L. Cowart, Yusuf A. Hannun, Thomas J. Lyons “Sphingolipids function
as downstream effectors of a fungal PAQR receptor”. Molecular Pharmacology 2009;75(4):866875.
Jessica L. Smith, Brian R. Kupchak, Ibon Garitaonandia, Kim L. Hoang, Andrew S. Maina,
Lisa M. Regalla, Thomas J. Lyons “Heterologous expression of human mPRα, mPRβ and mPRγ
in yeast confirms their ability to function as membrane progesterone receptors”. Steroids
2008;73(11):1160-1173.
Brian R. Kupchak, Ibon Garitaonandia, Nancy Y. Villa, Matthew B. Mullen, Marilee G.
Weaver, Lisa M. Regalla, Elizabeth A. Kendall, Thomas J. Lyons “Probing the mechanism of
FET3 repression by Izh2p overexpression”. Biochimica et Biophysica Acta Molecular Cell
Research 2007; 1773(7):1124–1132.
PRESENTATIONS
Speaker at the Abcam conference: Stochastic Events in Stem Cell Differentiation and
Reprogramming, Las Vegas, NV, October 2010.
Ibon Garitaonandia, Gerald K. Wambua, Jordan R. Seldeen, Ha Tran, Ileana L. Slavin,
Candace Lynch, Gulsah Altun, Jeanne F. Loring, Louise C. Laurent, “Culture methods can
influence the genetic stability and phenotypic properties of human embryonic stem cells”, The
Scripps Research Institute 2010 Fall Research Symposium, La Jolla, CA, September 2010.
Ibon Garitaonandia, PhD 3
Guest speaker at the Roche Applied Science xCELLigence Symposium, San Diego, CA, October
2010.
Guest speaker at The 4th Suranaree University of Technology Stem Cell Workshop Proceedings,
Nakhon Ratchasima, Thailand, July 2010.
Ibon Garitaonandia, Gerald K. Wambua, Jordan R. Seldeen, Ha Tran, Ileana L. Slavin,
Candace Lynch, Gulsah Altun, Jeanne F. Loring, Louise C. Laurent, “Culture methods can
influence the genetic stability and phenotypic properties of human embryonic stem cells”,
International Society for Stem Cell Research 8th Annual Meeting, San Francisco, CA, July 2010.
Haipeng Xue, Ibon Garitaonandia, Peng Jiang, Ha Tran, Chad MacArthur, Mahendra S. Rao,
Wenbin Deng, Louise C. Laurent, Jeanne F. Loring, Ying Liu, “Gene targeting in human
pluripotent stem cells”, International Society for Stem Cell Research 8th Annual Meeting, San
Francisco, CA, July 2010.
Johanna Goldman, Franz-Josef Mueller, Peter Loeser, Ibon Garitaonandia, Jeanne F. Loring,
“The teratoma assay- A worthy gold standard for the assessment of pluripotency?”, International
Society for Stem Cell Research 8th Annual Meeting, San Francisco, CA, July 2010.
Ha Tran, Ileana Slavin, Gulsah Altun, Candace Lynch, Ibon Garitaonandia, Jeanne F. Loring,
Louise C. Laurent “Accumulation of genetic aberrations in the generation and long-term passage
of human induced pluripotent stem cells”, International Society for Stem Cell Research 8th
Annual Meeting, San Francisco, CA, July 2010.
Ibon Garitaonandia, Jordan R. Seldeen, Gerald K. Wambua, Igor Ulitsky, Sarah Murray,
Jeanne F. Loring, Louise C. Laurent “The effects of culture methods on the genetic and
phenotypic stability of human embryonic stem cells” California Institute for Regenerative
Medicine 2010 Grantee Meeting, San Francisco, CA, March, 2010.
Louise C. Laurent, Ha Tran, Ileana Slavin, Candace Lynch, Ibon Garitaonandia, Jeanne F.
Loring “Accumulation of genetic aberrations in the generation and long-term passage of human
induced pluripotent stem cells” California Institute for Regenerative Medicine 2010 Grantee
Meeting, San Francisco, CA, March 2010.
Ibon Garitaonandia, Igor Ulitsky, Sarah Murray, Jeanne F. Loring, Louise C. Laurent “The
effects of culture methods on the genetic and phenotypic stability of human embryonic stem
cells”, Sanford Consortium for Regenerative Medicine Stem Cell Meeting on the Mesa 4th
Annual Meeting, La Jolla, CA, November 2009.
Ibon Garitaonandia, Igor Ulitsky, Jeanne F. Loring, Louise C. Laurent “The effects of culture
methods on the genetic and phenotypic stability of human embryonic stem cells”, Society for
Biomolecular Sciences Symposium, Screening Stem Cells: From Reprogramming to
Regenerative Medicine, Boston, MA, September 2009.
Ibon Garitaonandia, PhD 4
Ibon Garitaonandia, Igor Ulitsky, Jeanne F. Loring, Louise C. Laurent “The effects of culture
methods on the genetic and phenotypic stability of human embryonic stem cells”, International
Society for Stem Cell Research 7th Annual Meeting, Barcelona, Spain, July 2009.
Jang-Won Lee, Samuel H. Wood, Ibon Garitaonandia, Louise C. Laurent, Roman Jimenez,
Jeanne F. Loring, Jeannie M. Fontana “Generation of disease specific human blastocysts
following interspecies somatic cell nuclear transfer (iSCNT) with ALS fibroblasts and pig
oocytes”, International Society for Stem Cell Research 7th Annual Meeting, Barcelona, Spain,
July 2009.
Ibon Garitaonandia, Igor Ulitsky, Sarah Murray, Jeanne F. Loring, Louise C. Laurent “SNP
genotyping analysis as a tool to asses genetic stability of human embryonic stem cells”, San
Diego Cell Biology Meeting, Salk Institute for Biological Studies, La Jolla, CA, April 2009.
Louise C. Laurent, Igor Ulitsky, Suzanne Peterson, Ibon Garitaonandia, Ron Shamir, Jeanne F.
Loring “Integrated analysis of recurrent regions of copy number variation and gene coexpression
in human embryonic stem cells” 2009 Cold Spring Harbor Laboratory Meetings, Systems
Biology: Networks, Cold Spring Harbor, NY, March 2009.
Ibon Garitaonandia, Igor Ulitsky, Sarah Murray, Jeanne F. Loring, Louise C. Laurent “SNP
genotyping analysis as a tool to asses genetic stability of human embryonic stem cells”, Sanford
Consortium for Regenerative Medicine Stem Cell Meeting on the Mesa 3rd Annual Meeting, La
Jolla, CA, November 2008.
Jessica L. Smith, Ibon Garitaonandia, Brian R. Kupchak, Thomas J. Lyons “Expression and
characterization of human membrane progestin receptors in Saccharomyces cerevisiae”,
American Society for Biochemistry and Molecular Biology, San Diego, CA, April 2008.
Brian R. Kupchak, Nancy Y. Villa, Ibon Garitaonandia, Lidia Kulemina, Jessica L. Smith,
Elizabeth A. Kendall, Lisa M. Regalla, Marilee G. Weaver, Mathew B. Mullen, Jerry R. Jin,
Anuj Kumar, Thomas J. Lyons “Yeast receptors for plant proteins and metal metabolism: a new
model for host-pathogen interactions”, Cell Biology of Metals, Gordon Research Conference,
Salve Regina University, Newport, RI, July 2007.
Ibon Garitaonandia, Jessica L. Smith, Brian R. Kupchak, Thomas J. Lyons “PAQR receptors,
identification of PAQR3 as a new adiponectin receptor”, American Chemical Society Florida
Annual Meeting and Exposition 2007, Orlando, FL, May 2007.
Jessica L. Smith, Ibon Garitaonandia, Brian R. Kupchak and Thomas J. Lyons, “Functional
characterization of human membrane progestin receptors using Saccharomyces cerevisiae”,
American Chemical Society Florida Annual Meeting and Exposition 2007, Orlando, FL, May
2007.
Brian R. Kupchak, Ibon Garitaonandia and Thomas J. Lyons, “Binding of adiponectin and
Tumor Necrosis Factor-alpha to AdipoR1 on the surface of yeast spheroplasts”, American
Chemical Society Florida Annual Meeting and Exposition 2007, Orlando, FL, May 2007.
Ibon Garitaonandia, PhD 5
PATENTS
Thomas J. Lyons, Brian R. Kupchak, Jessica L. Smith, Ibon Garitaonandia “High Throughput
Assays for Inhibitors and Activators of PAQR Receptors”. PCT/US2008/077304
WO/2009/042561.
AWARDS AND FUNDING
Winner of the poster award at the Abcam conference: Stochastic Events in Stem Cell
Differentiation and Reprogramming, Las Vegas, NV, October 2010.
CIRM Postdoctoral Fellow 2009-present
O’Keeffe Foundation Postdoctoral Fellow 2008-2009
University of Florida Chemistry Teaching Award 2006-2007.
MENTORING
Co-mentored three CIRM interns at the Scripps Research Institute.
Mentored three undergraduate students at the University of Florida.
PROFESSIONAL ASSOCIATIONS
Member of the International Society for Stem Cell Research.
Member of the American Chemical Society.