2 nd Conference Agenda Annual Personalized Nanomedicine Symposium Miami, FL January 29th, 2015 Registration 7:30 AM – 8:00 AM MARC Pavilion 11200 SW 8 Street, University Park, Florida International University, Miami Welcome - Breakfast 8:00 AM – 8:05 AM Welcome Speech Karla S. Munoz, MS, MBA Master of Ceremony - SPNM Secretary 8:05 AM – 8:15 AM Kenneth Furton, Ph.D. Provost and Executive Vice President, Florida International University Chief Operating Officer 8:15 AM – 8:25 AM John Rock, M.D., M.S.P.H. Founding Dean, Florida International University Herbert Wertheim College of Medicine Senior Vice President for Health Affairs 8:25 AM – 8:30 AM Madhavan Nair, PhD SPNM Founding President Keynote Speaker 8:30 AM – 8: 50 AM Piotr Grodzinski, Ph.D. Director of Nanotechnology for Cancer Programs at NCI National Cancer Institute (NCI) National Institutes of Health (NIH) Title: Cancer Nanotechnology: Current Status and Future Opportunities Introduced by Carolyn Runowicz, M.D. Executive Associate Dean for Academic Affairs Professor of Obstetrics and Gynecology Herbert Wertheim College of Medicine, Florida International University Former President of American Cancer Society Session 1 Design and Development of Nanoparticles for Personalized Nanomedicine Chair: Rao Rapaka, Ph.D. Branch Chief of Chemistry and Physiological Systems Research Branch (CPSRB) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) Chair: Richard Cote, M.D. Professor and Chairman, Department of Pathology Director of BioNIUM University of Miami 8:50 AM – 9:20 AM Plenary Speech: Nanotech in Personalized Medicine Larry Nagahara, Ph.D. Director, Physical Sciences- Oncology Division of Cancer Biology National Cancer Institute (NCI) National Institutes of Health (NIH) Introduced by: Amir Mirmiranm, Ph.D., PE, ASCE, ACI Vasant H. Surti Professor and Dean, College of Engineering and Computing Florida International University 9:20 AM – 9:40 AM Engineering of Soft Nanomaterials for Drug Delivery in Cancer S1: Tatiana Bronich, Ph.D. Professor and Center for Drug Delivery and Nanomedicine, Codirector University of Nebraska Medical Center 9:40 AM – 10:00 AM Conjugated Polymer Nanoparticles for Biomedical Imaging and Therapeutic Delivery S2: Joong Ho-Moon, Ph.D. Associate Professor, Department of Chemistry and Biochemistry Florida International University 10:00 AM – 10:20 AM Nanobiology Approach to Protect Neurons from Oxidative Stress S3: Anuja Ghorpade, Ph.D. Chairman and Professor, Cell Biology and Immunology University of North Texas 10:20 AM – 10:30 AM BREAK Session 2 Theranostics for Personalized Nanomedicine Chair: Larry Nagahara, Ph.D. Director, Physical Sciences- Oncology Division of Cancer Biology National Cancer Institute (NCI) Chair: Sylvia Daunert, Ph.D. Professor and Lucille P. Markey Chair, Department of Biochemistry and Molecular Biology University of Miami 10:30 AM – 10:50 AM Advanced Manufacturing for Personalized Nanomedicine Plenary Speech: Kaiming Ye, Ph.D. Professor and Chair, Department of Bioengineering Stem Cell and Tissue Engineering Laboratory Binghamton University Introduced by: Chenzhong Li, Ph.D. Associate Professor, Biomedical Engineering Florida International University 10:50 AM – 11:10 AM Nanobiotechnology and Nanomotor: Single Pore High Throughput DNA Sensing, Single Molecule Detection, Single Fluorescence Imaging, and RNA Nanotechnology S1: Peixuan Guo, Ph.D. Professor and William Farish Endowed Chair in Nanobiotechnology Director, Nanobiotechnology Center University of Kentucky 11:10 AM – 11:30 AM Quantitative Cardiac Imaging for Cocaine-Induced Subclinical Atherosclerosis in Patients and Future Perspective S2: Shenghan Lai, M.D., M.P.H. Professor of Pathology Joint of Psychiatry and Behavioral Sciences Professor of Radiology and Radiological Science John Hopkins University 11:30 AM – 11:50 AM NeuroImaging for Theranostics in Personalized Medicine S3: Matthew Sutherland, Ph.D. Assistant Professor, Department of Psychology Florida International University 11:50 AM – 12:10 PM Targeted Theranostic Nanoparticles for Cancer: Imaging, Chemotherapy, and Thermotherapy S4: Anthony McGoron, Ph.D. Professor, Biomedical Engineering Undergraduate Program Director Florida International University 12:10 PM– 1:15 PM LUNCH BREAK 1:15 PM – 2:30PM Poster Session NIDA Workshop- “Early Career Program for Basic Chemists in Drug Abuse & Addiction Research” Dr. Kristopher Bough (NIDA) Dr. Jag Khalsa (NIDA) Session 3 Nanomedicine for Cancer and Degenerative Disease Chair: Piotr Grodzinski, Ph.D. Director of Nanotechnology for Cancer Programs at NCI National Cancer Institute (NCI) National Institutes of Health (NIH) Chair: Howard Fox, M.D., Ph.D. Professor, Pharmacology and Experimental Neuroscience Senior Associate Dean, UNMC Research and Development University of Nebraska Medical Center 2:35 PM – 2:55 PM Team Science @ BioNIUM Plenary Speaker: Richard Cote, M.D. Professor and Chairman, Department of Pathology University of Miami Introduced by: Zubin J. Panthaki, M.D. Professor of Clinical Surgery Division of Plastic Surgery Professor of Clinical Orthopedics, and Associate Program Director for Plastic Surgery Residency Program Director, Hand Surgery Fellowship University of Miami 2:55 PM – 3:15 PM Obstacles to the Cure of HIV-1 S1: Mario Stevenson, Ph.D. Professor of Medicine Chief of the Division of Infectious Diseases University of Miami 3:15 PM – 3:35 PM Direct reprogramming of Neural Stem Cells and Specific Neural Precursors: Potential Application and Challenges in Nanomedicine S2: Jialin Zheng, M.D. Professor Associate Vice Chancellor for Academic Affairs Associate Dean for Graduate Studies Director, Asia Pacific Rim Development Program University of Nebraska Medical Center 3:35 PM – 3:55 PM Targeting Iron Homeostasis in Ovarian Cancer S3: Sundaram Ramakrishnan, Ph.D. Professor, Department of Pharmacology University of Minnesota 4:00 PM – 4:30 PM BREAK Session 4 Applications of Nanomedicine in HIV-1 and in Emerging Infectious Diseases Chair: Larry Nagahara, Ph.D. Director, Physical Sciences- Oncology Trans-NIH Nano Task Force Division of Cancer Biology National Cancer Institute (NCI) National Institutes of Health (NIH) Chair: Ram Datar, Ph.D. Associate Professor of Pathology, Biochemistry and Molecular Biology Co-Director of BioNIUM University of Miami Keynote Speaker 4:35 PM – 4:55 PM Rao Rapaka, Ph.D. Branch Chief of Chemistry and Physiological Systems Research Branch (CPSRB) National Institute of Health (NIH) National Institute on Drug Abuse (NIDA) Title: Future for Nanotechnology: NIDA’S Perspective Introduced by: Andres G. Gil, Ph.D. Vice President for Research Professor of Social Work Florida International University 4:55 PM – 5:15 PM Nanocure for Neuro-AIDS and Drug Addiction S1: Madhavan Nair, Ph.D. Distinguished Professor and Founding Chair, Department of Immunology Director, Institute of Neuroimmune Pharmacology Associate Dean, Biomedical Research Florida International University 5:15 PM – 5:35 PM Rapid Nanodetection of Ebola Infection at Point of Care S2: Aileen Marty, M.D., FACP Professor, Department of Medicine Director, FIU Health Travel Medicine Program and Vaccine Clinic 5:35 PM – 5:55 PM The Role of Autophagy in NeuroAIDS and Therapeutic Implications S3: Nazira El-Hage, Ph.D. Associate Professor, Department of Immunology Florida International University 5:55 PM – 6:15 PM Near Infrared Immunoflourescent Guided Identification of Ghrelin Producing Cell in Gastric Fundus S4: Raul Rosenthal, M.D. Professor and Chief of Staff, Department of General Surgery Cleveland Clinic Florida 6:30 PM – 8:00 PM DINNER 7:30 PM – 8:00 PM BUSINESS DINNER (Executive Committee Members only) 8:15 PM Bus Leaves to Sofitel Miami January 30th, 2015 8:00 AM – 8:25 AM 8:25 AM – 8:30 AM BREAKFAST Richard J. Noel Jr., PhD Master of Ceremony - SNIP Meetings Committee Chairperson Session 5 New Frontiers in HIV and Substance Abuse Research – Part I Chair: Sulie Chang, Ph.D. Professor, Department of Biological Sciences Director, Institute of NeuroImmunne Pharmacology Seton Hall University Chair: Alexandros Makriyannis, Ph.D. Professor, Chemistry and Chemical Biology and Pharmaceutical Sciences George D. Behrakis Endowed Chair in Pharmaceutical Biotechnology Director of the Center for Drug Discovery Northeastern University 8:30 AM – 8:50 AM Drug Abuse and HIV Research at NIDA/Consequences and Clinical Management Plenary Speaker: Jag Khalsa, Ph.D. Chief, Medical Consequences Branch Division of Pharmacotherapies and Medical Consequences National Institute of Health (NIH) National Institute on Drug Abuse (NIDA) Introduced by: Raul Gonzalez, Ph.D. Associate Professor, Department of Psychology Director, Substance Use and HIV Neuropsychology Lab 8:50 AM – 9: 10 AM HIV and Morphine Mediated Neuronal Dysfunctions: Blaming the Messenger S1: Shilpa Buch, Ph.D. Professor and Vice-Chair of Research, Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical Center 9:10 AM – 9:30 AM Gene Editing Strategy for Eradicating HIV-1 from Latently Infected Human Cells S2: Kamel Khalili, Ph.D. Laura H. Carnell Professor and Chair, Department of Neuroscience Director, Center for Neurovirology Director, Comprehensive NeuroAIDS Center Temple University School of Medicine 9:30 AM – 9:50 AM HIV Interaction with Cocaine and Tat: Epigenetic and Neuroinflammation S3: Johnny He, Ph.D Professor, Department of Cell Biology and Immunology Associate Dean, GSBS University of North Texas Health Science Center 9:50 AM – 10:10 AM Transcriptome Profiling and Pathway Analysis of Genes Differentially Expressed in the Brain of HIV-1 Transgenic Rats Treated with Nicotine S4: Ming Li, Ph.D. Professor, Psychiatry and Neurobehavioral Sciences University of Virginia 10:10 AM – 10:30 AM BREAK Session 6 New Frontiers in HIV and Substance Abuse Research – Part II Chair: Lena Al-Harthi, Ph.D. Professor and Associate Chair, Department of Immunology and Microbiology Rush University Chair: Mahendra Kumar, Ph.D. Professor, Psychiatry and Behavioral Sciences and Psychology Director, Molecular Neuroendocrinology and Neurotransmitters Laboratory Chief, Laboratory of Psychoneuroendocrinology University of Miami 10:35 AM – 10:55 AM Can a Better Understanding of Endogenous Nano-systems inform the development of Nanomedicine? Plenary Speaker: Norman J. Haughey, Ph.D. Professor, Department of Neurology Division of Neuroimmunology and Neurological Infections Director, JHU NIMH Surrogate Markers Core John Hopkins University School of Medicin Introduced by: Mohan Sopori, Ph.D. Clinical Professor and Senior Scientist, College of Pharmacy Program Manager, Respiratory Immunology and Asthma Program, Love Lace Respiratory Research Institute, University of New Mexico 10:55 AM – 11:15 AM Novel Viral Determinants of HIV-1 Associated Neurocognitive Disorders S1: Vinayaka Prasad, Ph.D. Professor, Department of Microbiology and Immunology Director, Einstein’s AIDS International Training and Research Program Albert Einstein College of Medicine 11:15 AM – 11:35 AM Pericyte Dysfunctions in BBB impairment Caused by HIV infection S2: Yuri Persidsky, M.D., Ph.D. Chairperson and Professor, Department of Pathology and Laboratory Medicine Temple University 11:35 AM – 11:55 AM Role of Novel Endolysosome Mechanisms in Pathogenesis of AD and HAND S3: Jonathan Geiger, Ph.D. Chester Fritz Distinguished Professor Interim Chair, Department of Anatomy and Cell Biology Chair, Department of Pharmacology, Physiology and Therapeutics University of North Dakota 11:55 AM – 12:15 PM Perspective for Nanotoxicology in Future Medicine S4: Michal Toborek, M.D., Ph.D. Professor and Vice Chair for Research, Department of Biochemistry and Molecular Biology University of Miami 12:15 PM – 1:10 PM LUNCH Session 7 Early Investigators in Personalized Nanomedicine Research Chair: Kristopher Bough, Ph.D. Tobacco Regulatory Science Program (TRSP) Coordinator/HAS; Division of Neuroscience and Behavioral Research, National Institute on Drug Abuse (NIDA) National Institutes of Health (NIH) Chair: Sanjay Maggirwar, M.B.A., Ph.D Professor and Vice Chair, Department of Microbiology and Immunology (SMD) University of Rochester Medical Center 1:15 PM – 1:25 PM Anti-HIV Dual Loaded Sustained Release Core-Shell Nanoparticles for Therapy S1: Jessica Reynolds, PhD University of Buffalo 1:25 PM – 1:35 PM Nanoengineered Sustained Release Formulation for the CNS Viral Reservoir Eradication S2: Rahul Dev Jayant, PhD Florida International University 1:35 PM – 1:45 PM Brain-Derived Growth Factor (BDNF) signaling: Possible implications for BDNF bound magnetic nano carriers for the treatment of stroke S3: Pallab Bhattacharya, PhD University of Miami 1:45 PM – 1:55 PM Influence of Hyperthermia on Nanoparticle Transport Dynamics in 2D-Monolayer cultures and 3-D Tumor spheroids S4: Abhignyan Nagesetti, MS Florida International University 2:00 PM – 2:45 PM Panel Discussion: 2:45 PM – 3:30 PM Award Ceremony 3:30 PM – 3:40 PM Closing Remarks Jag Khalsa, Ph.D. Tatiana Bronich, PhD Sabita Roy, Ph.D Ram Datar, Ph.D. Michal Toborek, M.D., Ph.D.