Pearls For Cleft Lip and Palate Surgery Kevin S. Smith, DDS Comprehensive Evaluation and Team Care for Cleft and Craniofacial Patients Dental Hygiene Alumni Association September 25,2015 Kevin S Smith, DDS Professor and Residency Program Director Oral and Maxillofacial Surgery University of Oklahoma Kevin S Smith DDS Kevin-smith@ouhsc.edu 405-271-4955 www.oralfacialsurgeons.com Donate to: A Smile for a Child Foundation (501c3 foundation) 1000 N Lincoln STE 2000 OKC OK 73104 www.oklahomacleft.org Keep sight of the big picture Interdisciplinary care is most important Must provide a roadmap for the family Coordinate care between critical specialties Cleft Lip and Palate Embryology Embryology etiology Why ? Epidemiology Left > Right CL/P Isolated CP 2:1 M>F 2:1 F>M 2:1 1:660 live births (USA) Epidemiology Highest incidence in Asians and Native Americans (1:500) African Americans lowest incidence(1:2000) Increase in Incidence? Falling perinatal mortality Decreased operative mortality Importance of intermarriage Types of Clefts Sequela of clefts Feeding Ear Problems Speech Difficulties Dental Problems Malocclusion Nasal Deformity Interdisciplinary Team Care American Cleft Lip and Palate- Craniofacial Association(ACPA) Surgeon (OMFS, ENT or Plastics), Orthodontics, Speech and Language Pathology The Univ. of Ok J. W. Keys and M. K. Chapman Cleft Palate-Craniofacial Clinic Genetics, Audiology, Social work, Pediatric dentistry, Prosthodontics, Psych Counseling, Nursing, ENT Interdisciplinary Team Care American Cleft Lip and Palate- Craniofacial Association(ACPA) Surgeon (OMFS, ENT or Plastics), Orthodontics, Speech and Language Pathology The Univ. of OKlahoma J. W. Keys Cleft Palate-Craniofacial Clinic Genetics, Audiology, Social work, Pediatric dentistry, Prosthodontics, Psych Counciling, Nursing, ENT Funding PAtients Funding PAtients Keep skills with Missions Surgical Sequence General Therapeutic Goals PArameters of Care (AAOMS PArCare07) Optimization of the psychologic impact on patient and family Limited period of disability Improved social and psychologic development Limited adverse maxillofacial growth and development Minimal scar formation General Therapeutic Goals PArameters of Care (AAOMS PArCare07) Appropriate understanding by patient (family) of treatment options and acceptance of treatment plan Appropriate understanding and acceptance by patient (family)of favorable outcomes, known risks and complications Absence of infection It isn’t Really about Closing the “hole” PRenatal Diagnosis Prenatal Diagnosis High resolution 3D ultrasound Must thoroughly image the face Cases Comprehensive Care for Cleft Lip and Palate 4d ultrasound Prenatal Counseling Genetics Feeding Surgical repair Educational literature and internet connections Feeding Your Baby Weight Gain is KEY Haberman Pigeon Prenatal Counseling Parents are knowledgeable about clefting Feeding skills with SpecialNeeds® Feeder (Haberman) are reinforced at birth Different Severity of Clefts Unilateral Cleft Lip: Incomplete Wide early p Complete Different Severity of Clefts The Bony Cleft For Wide Clefts… Options to help narrow the cleft prior to surgery: Lip Taping Nasoalveolar Molding Lip Adhesion Surgery Lip Taping Start taping at first visit & change tape daily Nasoalveolar Molding (NAM) Impressions, “retainer” made Taping, elastics, nasal lift Weekly Adjustments for 8-12 wks Nasoalveolar Molding (NAM) Nasoalveolar Molding Appliance for the Treatment of Primary Cleft Lip and Palate Kevin S. Smith, DDS University of OklahomaCenter for Cleft and Facial Deformities Nasoalveolar Molding Presurgical orthopedics has been controversial growth orthodontic benefits Presurgical orthopedics, Latham Presurgical orthopedics, Latham Improves surgical results? nasal symmetry improvement esthetic effects on the lip Principles Technique Impression of maxilla 2-4 weeks Acrylic appliance Perma-soft Elastics on steri strips Coloplast next to skin Adjustments weekly Four to eight weeks Enhance with lip-tape adhesion Goals of Alveolar Molding Controlled movement of alveolar segments Gingival tissue approximation Alignment of nasal base Nasal Stint alveolar cleft < 6mm .030 wire active at apex of nasal cartilage soft liner to prevent soft tissue damage Nasal manipulation elevates deformed cartilage Four weeks of molding Unilateral Advantages Guide alveolar segments into contact Decrease surgical tension Reposition nasal base Manipulate cartilage and nasal tip Reduction in secondary bone grafting? Decrease costs and revisions? Bilateral Goals Lengthen columella Align alveolar segments and premaxilla Complications Soft tissue breakdown Premature tooth exposure Parental non-compliance Conclusions Reshapes the nose Reduces the size of cleft Makes repair easier and less traumatic Does not make bilateral repair easier or less complicated Can this technique reduce secondary surgery? Lip Adhesion Two stage repair of WIDE Cleft Lips Initial Visit 5 wks after stage one Primary Repair of Cleft Lip Rule of “over 10’s” Wilhelmsen and Musgrave (1966) Over 10 pounds Over 10 g hemoglobin Over 10 weeks old WBC less than 10,000 Final Repair Historical Review Millard First Rotation-Advancement for Cleft Lip Repair, Korea, 1955. Goals of Cleft Lip Repair Approximation of cleft edges Maintenance of natural landmarks Cupids bow Philtral dimple Goals of Cleft Lip Repair Muscle approximation Alar base balance and symmetry Scar in natural lines Instruments and suture 15-C blade Smaller than a 15 Instruments and suture Lorenz “Power Cut” TC curved Iris scissors 3-0 monocryl (nasal cinch) 4-0 vicryl on P-3 needle (deep and muscle) 4-0 vicryl “rapide” on P-3 5-0 plain gut on P-3 Bilateral Lip repair in 2 stages Bilateral Cleft Lip Repair Too Wide Cleft Palate Repair Is not an infection!!! Repair Considerations Feeding Speech and swallowing Maxillary growth and dental occlusion Advantages- Early closure Better palatal and pharyngeal muscle closure Facilitate Feeding Better phonation skills Improve auditory tube function Assist oral hygiene Improve psychological aspects (parents and baby) Disadvantages - Early closure Difficult surgical closure SCAR FORMATION Historical Review Obturation was the preferred method of treatment until the 19th century Von Graefe (1816) described surgical closure of cleft Von Langenbeck (1859) emphasized subperiosteal undermining and bipedical flaps Historical Review Veau (1931) described single pedicle flaps based on the greater palatine artery Wardill and Kilner (1937) modified the Veau technique to increase palatal length Furlow (1980) developed double reversing Z-plasty palatoplasty to facilitate muscular reconstruction Palatal Repair One stage Closure of hard and soft palate simultaneously Early speech intervention May cause major disturbances in maxillary growth Palatal Repair Two stage Staphylorrhaphy 18 months Palatorrhaphy 4 years Two Stage Advantages Less effect on maxillary transverse growth Disadvantages More articulation errors Two Flap Technique Wardill-Kilner-Veau Two Flap Technique Instruments and suture 69-B Beaver Instruments Sinus Lift Curettes Opposing Z-plasty 30°: 25% 45°: 50% 60°: 75% OpPosing Z-Plasty Furlow Modified Bipedicle Flap Von Langenbeck Submucous Cleft Velopharyngeal Insufficiency VPI Definitions Velopharyngeal Inadequacy Generic term used to denote abnormal VP function Velopharyngeal insufficiency- Structural defects of the velum or pharyngeal walls at the level of the nasopharynx; not enough tissue or a mechanical interference that prevents closure Velopharyngeal incompetence- Includes neurogenic etiologies, impaired motor control. Velopharyngeal mislearning- other causes Surgical management of mechanical and soft tissue problems can have great Surgical management for neurologic etiologies can be difficult. (Velopharyngeal Incompetence) Resonance changes The sound waves of speech enter both the oral cavity and the nasal cavity This resonance change is typically called hypernasality Factors include structural differences, tissue mass, lingual/labial/tongue movement, nasal resistance and timing. Etiology Cleft palate Etiology Submucous Cleft Etiology Short palate Removal of adenoids Etiology Neuromuscular Deficits VCFS Diagnosis Speech and Language Pathologist Will usually be the first line finding the problem Pediatricians or parents will say that there is a problem with intelligibility VPI may be found very early but objective clinical assessment usually doesn’t take place until cooperation of the child. Diagnosis Speech and Language Pathologist Signs and Symptoms Nasal Grimace Nasal Emissions Increased Nasal Airflow Hypernasality Speech and Language Pathologist Need adequate speech sample List of sentences with a particular phonetic makeup of each utterance Mama made lemon jam. Give Gary the chocolate cake. Cleft team patient will usually be monitored School age screening in schools is important as a catch-all Burned Bridges and Missed Opportunities Infants with glottal stops and pharyngeal fricatives Can be recognized and intercepted Therapy contrary to speech development Sign Can the child communicate with more than just his parents? Are the parents learning sign? Limited application might be OK??? Alternative to Sign Language Work on articulation Work on correction of Glottal Stops and Fricatives regardless of Resonance Activate the velopharyngeal valve Questions about what to do should be directed to colleagues who work in this area Multi-view Videofluoroscopy Must have consistent VPI Evaluation by SLP Articulation correction (attempted) by SLP Work to over come glottal stops Age- must be cooperative (Average age- 4.5 years) Multi-view Videofluoroscopy Barium coating of pharynx Views Lateral SMV (Base view)NormaVPIToo young!!! Velopharyngeal Insufficiency Diagnosis SLP or Surgeon Nasopharyngoscopy Nasal spray- 2% Pontocaine in atomizer Insertion into larger size nostril Evaluate palatal movement Evaluate lateral wall movement Evaluate tonsils and adenoids Removal of adenoids Medical Intervention Prosthetics Palatal lengthening Pharyngeal flaps Posterior wall implants Sphincter Pharyngoplasty Obturation, Bulbs and Lifts Posterior Wall Implants Small Defects Silastic Autogenous Opposing Z-plasty 30°: 25% 45°: 50% 60°: 75% OpPosing Z-Plasty Furlow Two Flap Technique Wardill-Kilner-Veau Two Flap Technique Pharyngeal Flap Superiorly based Pharyngeal Flap Pharyngeal Flap Inferiorly Based Pharyngeal Flap Pull Through Sphincter Pharyngoplasty Bardach Consider for VCFS with obturator Hospital Course PICU Tongue Stitch Steroids Cautious pain control Velopharyngeal Insufficiency Must include intensive speech therapy in the post surgical phase Child will still have resonance problems after surgical intervention Complications Bleeding OSAS Acute airway obstruction Nasal obstruction Continued VPI (~10%) 22q11.2 deletion syndrome Cardiac Abnormality (Tetralogy of Fallot) Abnormal facies Thymic aplasia Hypocalcemia Cleft palate Apraxia Alveolar Cleft Repair Sequela of Alveolar Clefts Unsupported alar bases producing nasal asymmetry Oronasal fistula Maxillary transverse hypoplasia Lack of bone support for teeth adjacent to cleft Sequela of Alveolar Clefts Crowding of teeth Speech misarticulations Frequent supernumerary teeth Missing lateral incisors Sequela of Alveolar Clefts Bilateral clefts Mobile premaxilla More transverse hypoplasia Protrusion of the premaxilla Indications for Grafting Functional Unite dento-osseous segment Prevent arch collapse after expansion Augmentation of alveolar ridge Osseous support of teeth Closure of oronasal fistula Improvement of speech Indications for Grafting Aesthetic Alar base support Restore contour of anterior maxilla Improving lip support Base for improving dental aesthetics Timing of Grafting Primary bone grafting < 2 years Rib or tibia used as graft Restricts facial growth potential Resorption of graft, need for second graft Timing of Grafting Early secondary grafting 2-6 years Iliac crest may be used Restricts facial growth potential Resorption of graft, need for second graft Timing of Grafting Secondary grafting 7-12 years Dental age versus chronological age Grafting in mixed dentition has highest success Permanent cuspid should be high in alveolus 1/2 to 3/4 root formation 90% of palatal transverse growth is complete at age 7 Timing of Grafting Late secondary After cuspid eruption Minimal influence over maxillary growth Potential loss of teeth Considered only when patient presents late Orthodontics Depending on orthodontic technique expansion takes place 3-6 months prior to grafting Easier to graft expanded maxilla than and cleft alveolus that is collapsed Cuspid Eruption 27% spontaneous eruption 17% require surgical exposure 56% require surgical exposure and orthodontic traction El Deeb (1982) rHBMP-2 Volumetric Cleft Changes in Treatment with Recombinant Human BMP-2/Absorbable Collagen Sponge/ Beta-Tricalcium Phosphate versus Grafts Robert Lawrence Trujillo, D.M.D. Frans Currier, DDS, MSD, M.Ed Kevin S Smith, DDS Research finished September 18, 2013 Materials and Methods: Surgical Protocol Three surgical protocols were used BMP/ACS/b-TCP Iliac Crest Mandibular Symphyseal Materials and Methods: Initial Cleft defect volume analysis Materials and Methods: Residual Cleft defect volume analysis Results: Percent Bone fill by treatm ent group Discussion The findings indicated Modified BMP protocol is acceptable Comparable to autogenous controls Age, initial defect volume, months to follow up CBCT Do not significantly influence % bone fill Weak correlation BMP Advantages Cost savings No hospital stay Spares autogenous bone options for tx DECREASE MORBIDITY! More research needed consider the effect (of what you do) on the end result Orthognathic Surgery Indications for Orthognathic Surgery Maxillary (midface) hypoplasia Class III malocclusion (Underbite) Apertognathia (Open Bite) Mandible can have variable growth Asymmetry Facial Growth needs to be complete Goals Normalize occlusion for functional and aesthetic improvement Able to move teeth into stable position in alveolus Improves prosthetic reconstruction potential Correction of skeletal base prior to soft tissue revision Surgical Procedure Splint to stabilize expansion Rigid fixation Overcorrection? Bone grafts (osteotomy and pyriform rim) Repair of nasal floor Problems with Orthognathic Surgery Scar tissue Speech Hearing Early Maxillary Distraction Done prior to completion of facial growth May eliminate need for future orthognathic surgery Always discuss the potential for future orthognathic surgery due to growth Psychosocial reasons Early Maxillary Distraction Cleft Distraction Orthognathic (Jaw) Surgery Before Orthognathic Surgery Distraction Osteogenesis Combination Treatment Large discrepancy done with distraction Final occlusion with traditional orthognathic surgery Must relate multiple surgeries to patient during initial treatment plan Combination Treatment Before, During & After Distraction Secondary procedures Secondary Rhinocheiloplasty Skeletal foundation must be intact Normalize facial proportions Implant restoration of Cleft Patients Endosseous Implants 1991 (Verdi, et al): First to report endosseous implant to restore the edentulous alveolar cleft region Implant successfully placed 18 months following closure of the oronasal fistula and reconstruction of the alveolar cleft with autogenous cancellous bone. Endosseous Implants Provides satisfactory functional and esthetic outcome Avoid the disadvantage associated with either prosthodontic or orthodontic options. Implant prerequisite: Adequate volume and quality of bone within alveolar cleft Implant Success Rates Conclusions