Anatomy & Physiology Basic Skeletal Structures
Skeletal System 3.6: Bone Formation – Endochondral Ossification
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Endochondral ossification occurs in long bones and most of the rest
of the bones in the body. The long bones, short bones, and the
irregular bones are responsible for producing e________ o_______.
1 intra oss 3
The long bones, short bones, and the irregular bones are responsible
for the five steps in e________ ossification.
2 long bone 6
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
3 endo ossify 1
Step 1 of the e_______ o________ is the development of the hyaline
cartilage model.
4 endo ossify 4
The hyaline c_______ m______ will grow in length by continuous
cell division of chondrocytes, which is accompanied by further
secretion of extracellular matrix.
5 endo ossify 8
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
6 endo ossify 12
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
7 endo ossify 1
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
8 endo ossify 12
1
9 endo ossify 6
During step 2, the h_______ c________ model grows in length and
thickness due to the additional ossification of the peripheral cartilage
surface.
The d_______ (shaft) of long bones, short bones and certain parts of
irregular bones begins to develop.
10 long bone 8
Step 2 is one of the fetal development stages, when the h______
c______ begins to change into the initial bone cells.
11 int ossifi 11
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the epiphyseal plate).
12 Endo ossify 13
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
13 endo ossify 1
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
14 endo ossify 12
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the e_______ p_____).
15 Endo ossify 13
16 endo ossify 14
Step 3 is the development of the primary ossification center. The
p______ o_________ c_______ is the first area of a bone to start
ossifying.
17 endo ossify 15
The first site where bone begins to form in the diaphysis of a long
bone or in the body of an irregular bone is the p_______ ossification
center.
The primary c____ of o_______, the diaphysis of the long bone, is
the first to form spongy bone tissue along the cartilage.
2
18 endo ossify 16
19 endo ossify 17
The first place in fetal long bones where the bone cells accumulate
along the fibers of hyaline cartilage is the primary o_________
center.
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
20 endo ossify 1
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
21 endo ossify 12
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the e_______ p_____).
22 Endo ossify 13
23 endo ossify 14
Step 3 is the development of the primary ossification center. The
p______ o_________ c_______ is the first area of a bone to start
ossifying.
24 endo ossify 18
The fourth step in bone formation is the development of the
secondary ossification center. The s_______ o______ c_____
develops in the epiphysis end of the bone.
The replacement of cartilage by bone at the e_______ of the long
bones is the site of the s_______ ossification center.
25 endo ossify 19
About the time of birth, a s________ o________ c_____ appears in
each end (epiphysis) of l_____ b_____.
26 endo ossify 20
In step 4, the s_______ o______ c_____ develops in the epiphysis
end of the bone.
27 bone 7
3
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
28 endo ossify 1
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
29 endo ossify 12
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the e_______ p_____).
30 Endo ossify 13
31 endo ossify 14
Step 3 is the development of the primary ossification center. The
p______ o_________ c_______ is the first area of a bone to start
ossifying.
In step 4, the s_______ o______ c_____ develops in the epiphysis
end of the bone.
32 bone 7
The fifth stage of bone growth is the formation of articular cartilage
and epiphyseal plate. Formation of articular cartilage and epiphyseal
plate are the final stage of e_______ o_______.
33 endo ossify 21
At the fifth stage hyaline cartilage is left on the ends of the bones,
called a______ c_______ and the e_______ plates are also formed.
34 endo ossify 22
Formation of a_______ c_______ and e_______ p______ are the
final stage of e_______ o_______.
35 endo ossify 23
In step 5, the bone completely calcifies except at the a_______
c_______ and the e_______ p______.
36 endo ossify 25
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
37 endo ossify 1
4
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
38 endo ossify 12
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the e_______ p_____).
39 Endo ossify 13
40 endo ossify 14
Step 3 is the development of the primary ossification center. The
p______ o_________ c_______ is the first area of a bone to start
ossifying.
In step 4, the s_______ o______ c_____ develops in the epiphysis
end of the bone.
41 bone 7
In step 5, the bone completely calcifies except at the a_______
c_______ and the e_______ p______.
42 endo ossify 25
The l____ bones, s_____ bones, and the i______ bones are
responsible for the five steps in endochondral o________.
43 Review
44
45
46
Step 1 of the cartilage model involves the conversion of some of the
h______ c_______ into the chondrocytes and chondroblasts of the
primary ossification center.
The d_______ and both e_______ of a long bone are separated by a
growing zone of cartilage (the e_______ p_____).
Step 3 is the development of the primary ossification center. The
p______ o_________ c_______ is the first area of a bone to start
ossifying.
In step 4, the s_______ o______ c_____ develops in the epiphysis
5
47
end of the bone.
48
In step 5, the bone completely calcifies except at the a_______
c_______ and the e_______ p______.
6