Name: ______________________________
Hour: ____
DNA Replication Review Worksheet
DNA Replication
1. What is the purpose of DNA replication?
2. What is the first step of DNA replication?
3. What enzyme is responsible for “unzipping” the DNA molecule?
4. What is the second step of DNA replication?
5. What is the role of DNA polymerase?
6. Explain how DNA replication is semi-conservative.
7. What is the end result of DNA replication?
8. Refer to the back of this worksheet for instructions for your DNA Replication drawing. Do not fill
out the grading rubric below.
Points
Possible
DNA Replication
 Detailed diagram of DNA Replication
At least 16 bases in length (1)
DNA Helicase correctly drawn and labeled (1)
Replication fork labeled (1)
DNA Polymerase correctly drawn and labeled (1)
7
Bases complementary on each strand (2) Original and New strands correctly labeled (1)

Correctly explained why DNA Replication is “semi-conservative” (1)
1
Points
Earned
Name: ______________________________
Hour: ____
In the space below, complete the following diagram:
DNA Replication Drawing: Refer to page 351 and notes
Detailed drawing showing the main steps of DNA replication for a DNA molecule at least 16 bases in
length. The following should be clearly illustrated in your diagram:
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The action of “DNA Helicase” in breaking the hydrogen bonds separating the two strands of DNA. You should also label the “replication fork”. Remember that the replication fork is the location where DNA Helicase is working.
The action of “DNA Polymerase” in guiding new DNA nucleotides into position.
The nitrogen bases on the drawing should be differentiated by color, and you should have a key
indicating which base is which color.
You do not need to differentiate between the sugar and phosphate groups on the backbone of
the DNA molecule. However, you need to color code the backbones so that it is clear which
strand is original and which strand is new.
Below your drawing, explain why the process of DNA Replication is referred to as semiconservative.