Student___________________________ Your Initials: ____ _____ _____ Block 2 3 4 A/B DNA Model Project I would suggest using wire or pipe cleaners as a framework, and using beads, Styrofoam balls, colored marbles, or some other item that you can support on the framework to represent sugars, phosphate groups, and the four nitrogen bases. That means you need six different colors or shapes, and a way to hold them together and support them. Nitrogen bases must be attached to the sugars, not the phosphates, and base pairing rules must be followed. Finally, the model must show the helical shape of DNA. NO PROJECT KITS (THOSE THAT YOU CAN BUY) WILL BE ACCEPTED. THIS PROJECT MUST BE YOUR OWN WORK. DATE ASSIGNMENT GIVEN: ______________ DUE DATE: ________________________ Note: you have been given a minimum of 2 weeks to complete this project. Projects turned in after the due date will incur a 20% penalty for being late. Adenine (A) – Green Thymine (T) – Black Guanine (G) – Yellow Cytosine (C) – Red Sugars and Phosphates – your choice as long as they are not the same as the Nitrogen Base colors. Possible Points 10 20 Project Instructions The model can either hang as a mobile or be mounted on a display stand or sturdy other sturdy material. The model is not fragile: it is sturdy enough to be handled and touched without breaking The DNA molecule depicts all four types of nucleotides (A, T, C and G) using the appropriate colors. The nucleotides are arranged correctly in complementary pairs (A-T, CG) The bases are correctly arranged according to the simplified codons that correspond to the builder’s initials. The sugar/phosphate “backbone” of the two helices is on the outside and bases of each nucleotide are internal to the backbone. The sugars and phosphates shown are attached at the appropriate location (nitrogen bases attached to the sugars). Model has a key representing all parts of the model. Student’s name is on the model. 10 Bonus – Creativity, design, uniqueness. 110 Total 25 25 10 10 Points Earned If you have any questions about structure or using materials that you have, please ask. I do not expect this to be an expensive project, so use what you have. Be creative with this model! Do not use anything that will spoil or create a mess. Do not make it too big. Remember, you have to get it to school in one piece. Your model should be between eight (8) and eighteen (18) inches, depending on what it is made of. It should have a minimum of nine base pairs represented. If you have an idea that doesn’t fit this description, please check with me first to make sure it will work and you will get maximum points. Have fun!! TURN IN THIS RUBRIC WITH YOUR PROJECT DNA Project Creating your base pairs Step 1: Write each letter of your initials in the blanks provided. Step 2: Look at the Simplified Codon column of Table 1 to find the DNA code for each letter of your initials. Step 3: Replace each letter of your initials with its threeletter codon. Use Table 1 to help you convert your name into its DNA sequence. Step 4: This is the original DNA strand. The other side of the strand should correspond to this strand using the base pairing rules. Fill in Table 2 with both strands. Your initials: ______ ______ _______ Table 2 Base Sequence LEFT side Base Colors: A=Green T=Black C=Red G=Yellow Base Sequence RIGHT side Table 1 Alphabet A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Simplified Codon GCT GCA TGC GAT GAG TTT GGG CAT ATA ATC AAG CTC ATG GAC GAT CCC GCG CGT TCA ACT ACG GTC TGG GTA TAC TAT