CURRICULUM VITAE
Jason G. McCoy
6616 Biochemistry Addition
Department of Biochemistry
University of Wisconsin-Madison
Madison, WI 53706
jmccoy@biochem.wisc.edu
CITIZENSHIP
US citizen
EDUCATION
8/93 – 12/97 B.S. Biology and Chemistry, Truman State University, Kirksville, MO
Fall, 2000
Predoctoral student, Department of Biochemistry, University of
Wisconsin-Madison, Madison WI
EMPLOYMENT
1/98 – 5/00 Monsanto (Research Biologist)
-Helped optimize a pilot plant scale protein purification process
-Employed as technology specialist for startup of Augusta-Dairy Manufacturing
facility
RESEARCH STATEMENT AND EXPERIENCE
My interests involve the use of electron microscopy and X-ray diffraction technology
as tools for acquiring molecular and atomic level detail for chemical and biological systems.
As an undergraduate I was involved in research projects which include studying the role of the
intergeniculate leaflet in the circadian rhythms of golden hamsters, kinetics of amino acid
transport in the intestine of the black bass, and using scanning electron microscopy to observe
pollen grain morphology. As a graduate student I have worked in the laboratory of a structural
biologist using X-ray crystallography to determine enzyme structure.
My current project involves the formation of three-dimensional, periodic solids using
the solvent channels of protein crystals as a template. These thick, structured materials would
potentially have properties ideal for X-ray optical applications. Characterization of the initial
and templated crystals as well as the final, isolated solids will be performed using X-ray
diffraction.
Standard X-ray crystallography employs the use of localized scattering elements which
can be used to deduce phase information. By filling the crystal interstices with scattering
elements, this localization is upset and currently available software packages would be unable
to pull out the proper phases. As a consequence, it will be necessary to write new software to
counter this problem.
RELEVANT COURSES TAKEN
Biochem 601 Protein and Enzyme Structure and Function
Biochem 612 Prokaryotic Molecular Biology
Biochem 660 Biochemical Techniques
Biochem 602 Biochemical Mechanisms of Regulation in the Cell
Chem 613 Chemical Crystallography
Chem 608 Symmetry, Bonding, and Molecular Shapes
Chem 665 Biophysical Chemistry
Biochem 905 Seminar, Biomolecular Structure
CS 302 Introduction to Programming
Biol 300 Genetics (Truman State Univ.)
Chem 421 Biochemistry (Truman State Univ.)
CS 174 Introduction to Computer Science (Truman State Univ.)
Math 263 Analytical Geometry/Calculus II (Truman State Univ.)
Math 264 Analytical Geometry/Calculus III (Truman State Univ.)
Stat 190 Basic Statistics (Truman State Univ.)