The DEGGE GROUP, LTD Drug Safety Research and Information Appendices Risk of Significant Infection in Rheumatoid Arthritis Patients Switching Anti-Tumor Necrosis Factor- Drugs 1616 North Fort Myer Drive, Suite 1430 Office (703) 276-0067 Arlington, Virginia 22209-3100 Fax (703) 276-0069 Table of Appendices APPENDIX A. Serious Infectious Diseases .................................................................... 2 APPENDIX B. Infectious Conditions ............................................................................... 6 APPENDIX C. J-Codes for Intravenous Antimicrobial Treatment.................................... 8 APPENDIX D. List of Intravenous Antibiotics.................................................................. 8 APPENDIX E. Procedural Codes for Joint Surgery in RA Patients ............................... 25 APPENDIX F. List of DMARDS .................................................................................... 40 APPENDIX G. J-Codes for DMARDS Used for Rheumatoid Arthritis Treatment .......... 40 APPENDIX H. List of Oral Corticosteroids .................................................................... 41 APPENDIX I. List of Antidiabetic Drugs ........................................................................ 42 APPENDIX J. List of Medications to Treat Asthma/COPD ............................................ 43 The Degge Group, Ltd. aTNF Switching Study A-1 03/08/2016 APPENDIX A. Serious Infectious Diseases Defined by Hospitalization or Requiring Intravenous Antibiotics ICD-9-CM Code Category / Code Description 001-009 Intestinal infectious diseases 001 Cholera 002 Typhoid and paratyphoid fevers 003 Other salmonella infections 004 Shigellosis 005 Other food poisoning (bacterial) 006 Amebiasis 007 Other protozoal intestinal disease 008 Intestinal infections other organisms 009 Ill-defined intestinal infections 010-018 Tuberculosis* 010 Primary tuberculous infection* 011 Pulmonary tuberculosis* 012 Other respiratory tuberculosis* 013 Tuberculosis of meninges and CNS* 014 TB intestine/peritoneum/mesenteric* 015 Tuberculosis of bones and joints* 016 TB of genitourinary system* 017 Tuberculosis of other organs* 018 Miliary tuberculosis* 020-027 Zoonotic bacterial diseases 020 Plague 021 Tularemia 022 Anthrax 023 Brucellosis 024 Glanders 025 Melioidosis 026 Rat-bite fever 027 Other zoonotic bacterial diseases 030-041 Other bacterial diseases 030 Leprosy* 031 Diseases due to other mycobacteria* 032 Diphtheria* 033 Whooping cough* 034 Strep sore throat and scarlet fever 035 Erysipelas 036 Meningococcal infection* 037 Tetanus* 038 Septicemia 039 Actinomycotic infections 040 Other bacterial diseases 041 Bacterial infection in other conditions The Degge Group, Ltd. aTNF Switching Study 2 03/08/2016 ICD-9-CM Code Category / Code Description 042 Human Immunodeficiency Virus 042 Human immunodeficiency virus disease (HIV) 045-049 Poliomyelitis/other non-arthropod viral diseases of CNS* 045 Acute poliomyelitis* 046 Slow virus infection of CNS* 047 Meningitis due to enterovirus* 048 Other enterovirus diseases of central nervous system* 049 Other viral diseases of CNS* 050-057 Viral diseases accompanied by exanthem 050 Smallpox 051 Cowpox and paravaccinia 052 Chickenpox 053 Herpes zoster 054 Herpes simplex 055 Measles 056 Rubella 057 Other viral exanthemata 060-066 Arthropod-borne viral diseases 060 Yellow fever 061 Denge 062 Mosquito-borne viral encephalitis 063 Tick-borne viral encephalitis 064 Viral encephalitis transmitted by unspecified arthropods 065 Arthropod-borne hemorrhagic fever 066 Other arthropod-borne viral diseases 070-079 Other diseases due to viruses & chlamydiae 070 Viral hepatitis* 071 Rabies 072 Mumps 073 Ornithosis 074 Diseases due to coxsackie virus 075 Infectious mononucleosis 076 Trachoma 077 Other conjunctiva disease virus/chlamidae 078 Other disease virus/chlamidiae 079 Viral/chlamydial infection 080-088 Rickettsioses & other arthropod-borne diseases 080 Louse-borne (epidemic) typhus 081 Other typhus 082 Tick-borne rickettsioses 083 Other rickettsioses 084 Malaria 085 Leishmaniasis 086 Trypanosomiasis 087 Relapsing fever 088 Other arthropod-borne diseases 090-099 Syphilis & other venereal diseases* The Degge Group, Ltd. aTNF Switching Study 3 03/08/2016 ICD-9-CM Code Category / Code Description 090 Congenital syphilis* 091 Early syphilis symptomatic* 092 Early syphilis latent* 093 Cardiovascular syphilis* 094 Neurosyphilis* 095 Other late syphilis with symptoms* 096 Late syphilis, latent* 097 Other and unspecified syphilis* 098 Gonococcal infections* 099 Other venereal diseases* 100-104 Other spirochetal diseases 100 Leptospirosis 101 Vincent's angina 102 Yaws 103 Pinta 104 Other spirochetal infection 110-118 Mycoses* 110 Dermatophytosis* 111 Other/unspecified dermatophytosis* 112 Candidiasis* 114 Coccidioidomycosis* 115 Histoplasmosis* 116 Blastomycotic infection* 117 Other mycoses* 118 Opportunistic mycoses* 120-129 Helminthiases 120 Schistosomiasis (bilharziasis) 121 Other trematode infections 122 Echinococcosis 123 Other cestode infection 124 Trichinosis 125 Filarial infection/dracontiasis 126 Ancylostomiasis and necatoriasis 127 Other intestinal helminthiases 128 Other/unspecified helminthiases 129 Intestinal parasitism, unspecified 130-136 Other infectious & parasitic diseases 130 Toxoplasmosis 131 Trichomoniasis 132 Pediculosis/phthirus infestation 133 Acariasis 134 Other infestation 135 Sarcoidosis 136 Other/unspecified infectious/parasitic disorder 137-139 Late effects of infectious & parasitic diseases 137 Late effects of tuberculosis The Degge Group, Ltd. aTNF Switching Study 4 03/08/2016 ICD-9-CM Code 138 139 Category / Code Description Late effects of acute poliomyelitis Late effect infect/parasitic disease * Selected conditions chosen to represent serious infections regardless of hospitalization or IV antibiotic administration. International Classification of Diseases, Ninth Revision, Clinical Modification. 9 th ed. Washington, DC: US Department of Health and Human Services, Centers for Disease Control and Prevention, Centers for Medicare and Medicaid Services; 2007. The Degge Group, Ltd. aTNF Switching Study 5 03/08/2016 APPENDIX B. Infectious Conditions Requiring Hospitalization or Intravenous Antibiotics ICD-9 Code 254.1 255.8 323.x 324.x 357.0 380.1 382.0 382.9 383.x 384.0 384.1 421.x 422.x 424.9 447.2 457.2 460 461.x 462 463 464.x 465.x 466.x 472 473.x 474.0 475 476.x 480 481 482 483 484 485 486 487.1 487.8 490 491.2 510.x 511.1 513.x 519.1 519.2 522.5 522.7 523.3 528.3 528.5 529.0 540-542 Code Description Abscess of thymus Oth disorders of adrenal gland - cortisol-binding globulin abnormality (for abscess) Encephalitis, myelitis, and encephalomyelitis Intracranial and intraspinal abscess Acute infective polyneuritis Infective otitis externa Acute suppurative otitis media Unspecified otitis media Mastoiditis and related conditions Acute myringitis without mention of otitis media Chronic myringitis without mention of otitis media Acute and subacute endocarditis Acute myocarditis Endocarditis, valve unspecified Rupture of artery (for artery ascess) Lymphangitis Acute nasopharyngitis [common cold] Acute sinusitis Acute pharyngitis Acute tonsilitis Acute laryngitis and tracheitis Acute upper respiratory infections of multiple or unspecified sites Acute bronchitis and bronchiolitis Chronic pharyngitis and nasopharyngitis Chronic sinusitis Chronic tonsilitis Peritonsillar abscess Chronic laryngitis and laryngotracheitis Viral pneumonia Pneumococcal pneumonia Other bacterial pneumonia Pneumonia due to other specified organism Pneumonia in infectious diseases classified elsewhere Bronchopneumonia, organism unspecified Pneumonia, organism unspecified Influenza with other respiratory manifestations Influenza with other manifestations Bronchitis, not specified as acute or chronic Obstructive chronic bronchitis Empyema Pleurisy with effusion, with mention of a bacterial cause other than tuberculosis Abscess of lung and mediastinum Other diseases of trachea and bronchus, NEC (for bronchial abscess) Mediastinitis Periapical abscess without sinus Periapical abscess with sinus Acute periodontitis Cellulitis and abscess of oral soft tissues Diseases of the lips (for labial abscess) Glossitis Appendicitis The Degge Group, Ltd. aTNF Switching Study 6 03/08/2016 ICD-9 Code 550.0 551.x 566 567.x 569.5 572 572.0 572.1 574.0 574.1 574.3 574.4 575.0 575.1 576.1 590.x 595.x 597.0 597.8 599.0 603.1 604.x 607.1 607.2 614.x 615.0 615.9 616.x 680.x 681.x 682.x 684 685.0 686.x 711.0 711.9 728.0 729.4 730.x 785.4 788.7 790.7 790.8 996.6 998.5 999.3 Code Description Inguinal hernia, with gangrene Other hernia of abdominal cavity, with gangrene Abscess of anal and rectal regions Peritonitis Abscess of intestine Liver abscess and sequelae of chronic liver disease Abscess of liver Portal pyaemia Calculus of gallbladder with acute cholecystitis Calculus of gallbladder with other cholecystitis Calculus of bile duct with acute cholecystitis Calculus of bile duct with other cholecystitis Acute cholecystitis Other cholecystitis Cholangitis Infections of kidney Cystitis Urethral abscess Other urethritis Urinary tract infection, site not specified Infected hydrocele Orchitis and epididymitis Balanoposthitis Other inflammatory disorders of penis Inflammatory disease of ovary, fallopian tube, pelvic cellular tissue and peritoneum Acute inflammatory diseases of uterus, except cervix Unspecified inflammatory diseases of uterus, except cervix Inflammatory disease of cervix, vagina, and vulva Carbuncle and furuncle Cellulitis and abscess of finger and toe Other cellulitis and abscess Impetigo Pilonidal cyst, without abcess Other local infections of skin and subcutaneous tissue Pyogenic arthritis Infectious arthritis Infective myositis Fasciitis, unspecified Osteomyelitis, periostitis, and other infections involving bone Gangrene Urethral discharge Bacteremia, unspecified Viremia, unspecified Infection and inflammatory reaction due to internal prosthetic device, implant, graft Postoperative infection Complications of medical care, other infections World Health Organization: Manual of the international statistical classification of diseases, injuries and causes of death. Ninth revision, Volume 1. Geneva, WHO 1977. The Degge Group, Ltd. aTNF Switching Study 7 03/08/2016 APPENDIX C. Medication Names Used to Define Intravenous Antibiotics* Generic Name Amikacin Ampicillin Ampicillin Sodium/Sulbactam Sodium Azithromycin Aztreonam Capreomycin Cefazolin Cefepime Cefotaxime Cefotetan Cefoxitin Ceftazidime Ceftizoxime Ceftriaxone Cefuroxime Cilastatin Cilastatin Sodium/Imipenem Ciprofloxacin Clavulanate Potassium Clindamycin Dalfopristin Dalfopristin-Quinupristin Daptomycin Dextrose Ertapenem Sodium Erythromycin Erythromycin Gluceptate Generic Name Erythromycin Lactobionate Gentamicin Imipenem Imipenem-Cilastatin Kanamycin Levofloxacin Linezolid Meropenem Metronidazole Moxifloxacin Nafcillin Norfloxacin Ofloxacin Oxacillin Piperacillin Piperacillin-Tazobactam Polymyxin B Sulfate/Trimethoprim Sulfate Quinupristin Streptomycin Sulbactam Sulfamethoxazole Sulfamethoxazole/Trimethoprim Tazobactam Sodium Ticarcillin Tobramycin Trimethoprim Vancomycin *NDC codes are not displayed due to the excessively large number of codes The Degge Group, Ltd. aTNF Switching Study 8 03/08/2016 APPENDIX D. Intravenous Antimicrobial Treatment J-Codes J Code Code description J0120 J0200 J0278 J0285 J0286 J0287 J0288 J0290 J0295 J0456 J0500 J0530 J0540 J0550 J0560 J0570 J0580 J0690 J0692 J0694 J0695 J0696 J0697 J0698 J0710 J0713 J0715 J0720 J0740 J0743 J0744 J0744 J0770 J0878 J1335 J1362 J1364 J1570 J1580 J1590 J1840 J1850 J1890 J1956 J2010 J2020 J2185 Injection tetracycline up to 250 mg Inj alatrofloxacin mesylate 100 mg Injection, amikacin sulfate, 100 mg (2006) Injection amphotericin B 50 mg Injection amphotericin B 50 mg (2000) Infection amphotericin B lipid complex 10 mg (2006) Inj ampho B cholesteryl sulfate complex 10 mg (2006) Injection ampicillin sodium 500 mg Inj ampclln sodim/sulbactam-1.5 g Injection azithromycin 500 mg (2006) Injection dicyclomine hcl up 20 mg Inj pen G benzathine & pcn G procaine up to 600k u (2006) Inj pen G benzathine & pcn G procaine up to 1.2m u (2006) Inj pen G benzathine & pcn G procaineup to 2.4m u (2006) Inj pen G benzathine up to 600k u (2006) Injection pen G benzathine up to 2.4m u (2006) Inj penicillin G benzathine up to 2.4m u (2006) Injection cefazolin sodium 500 mg Inj cefepime hydrochloride 500 mg Injection cefoxitin sodium 1 g Cefonocid sodium injection (1998) Injection ceftriaxone sodium-250 mg Inj sterl cefuroxime sodium-750 mg Cefotaxime sodium per g Injection cephapirin sodium up 1 g Injection ceftazidime per 500 mg Injection ceftizoxime sodium-500 mg Inj chloramphenicol sodium succinate up to 1 g (2006) Injection cidofovir 375 mg Inj cilastatin sodim imipenem-250mg Inj ciprofloxacin for iv infusion 200 mg (2006) Inj ciprofloxacin iv infus 200 mg Injection colistimethate sodium up to 150 mg (2006) Injection daptomycin 1 mg (2006) Injection ertapenem sodium 500 mg (2006) Erythromycin glucep / 250 mg (1998) Injection erythromycin lactobionate 500 mg (2006) Injection ganciclovir sodium 500 mg Injection garamycin gent to 80 mg Injection gatifloxacin 10 mg (2006) Injection kanamycin sulfate up to 55 mg (2006) Inj kanamycin sulfate up 75 mg Injection cephalothin sodium to 1 g Injection levofloxacin 250 mg Injection lincomycin HCl to 300 mg Injection linezolid 200mg Injection meropenem 100 mg (2006) The Degge Group, Ltd. aTNF Switching Study 9 03/08/2016 J Code J2280 J2460 J2460 J2510 J2540 J2543 J2700 J2770 J3000 J3260 J3320 J3370 J3490 J3490 J3490 J3490 J3490 J3490 J3490 J3490 S0016 S0017 S0024 S0032 S0034 S0039 S0040 S0072 S0073 S0074 S0077 S0081 S5017 S9494 S9500 S9501 S9502 S9504 S9539 Code description Injection moxifloxacin 100 mg (2006) Inj oxytetracycline HCl up to 50 mg (2000) Injection oxytetracycline HCl up to 50 mg (2006) Inj penicillin G procaine aqueous up to 600 k u (2006) Injection pcn G K+ to 600000 units Inj pip/tz 1 gram/0.125 grams Inj oxacillin sodium to 250 mg Injection quinupristin/dalfopristin 500 mg (150/350) (2006) Injection streptomycin up to 1 g (2006) Inj tobramycin sulfate to 80 mg Inj spectinomycin dihydrochloride up to 2 g (2006) Injection vancomycin hcl 500 mg UCD-amikacin sulfate 50 mg (2006) UCD-aztreonam 500 mg (2006) UCD-cefotetan (2006) UCD-clavulanate potass ticarcillin disodium 0.1-3 g (2006) UCD-clindamycin phosphate 150 mg (2006) UCD-minocycline hcl 100 mg (2006) UCD-nafcillin sodium 1 g (2006) UCD-rifampin 600 mg (2006) Injection amikacin sulfate 500 mg (2000) Inj amikacin sulfate 500 mg (2000) Injection ciprofloxacin, 200mg Inj nafcillin sodium 2 g (2000) Inj ofloxacin 400 mg (2000) Inj sulfamethoxazole and trimethoprim 10 ml (2000) Inj ticarcilln & clavulanate K+31 gm Injection amikacin sulfate 100 mg Injection aztreonam 500 mg Injection cefotetan disodium 500 mg Inj clindamycin phosphate 300 mg Inj piperacillin sodium 500 mg (2000) Antibiotic administration supplies (without pump), per day Hit antibiotic/antifungal; diem Hit antibiotic/antifungal; Q24 hrs Hit antibiotic/antifungal; Q12 hrs Hit ABx antiviral/antifungal; Q8 hrs Hit ABx antiviral/antifungal; Q4 hrs Administration of antibiotics, intravenously UCD -Unclassified drug. The Degge Group, Ltd. aTNF Switching Study 10 03/08/2016 APPENDIX E. List of ICD-9-CM Codes for Opportunistic Infections Dx Code 0030 004 0040 0041 0042 0043 0048 0049 006 0060 0061 0062 0063 0064 0065 0066 0068 0069 0072 0074 0080 00843 00849 0085 0088 010 0100 01000 01001 01002 01003 01004 01005 01006 01010 01011 01012 01013 01014 01015 01016 01080 01081 01082 01083 01084 01085 01086 01090 Description Salmonella Gastroenteritis Shigellosis Shigella Dysenteriae Shigella Flexneri Shigella Boydii Shigella Sonnei Other Shigella Infections Shigellosis Unspec Amebiasis Acute Amebic Dysentery Wo Abscess Chron Intestin Amebiasis Wo Abscess Amebic Nondysenteric Colitis Amebic Liver Abscess Amebic Lung Abscess Amebic Brain Abscess Amebic Skin Ulceration Amebic Infection Other Sites Amebiasis Unspec Coccidiosis Cryptosporidiosis Intestinal Infection Due To E Coli Intestinal Infec Campylobacter Intestinal Infec Other Bacteria Uns Bacterial Enteritis Other arthropod-borne diseases Primary Tuberculous Infection Primary Tuberculous Complex Primary Tuberculosis Complex Uns Exam Primary Tuberculosis Complex No Exam Primary Tuberculosis Complex Exam Unkn Primary Tuberculosis Complex Micro Dx Primary Tuberculosis Complex Cult Dx Primary Tuberculosis Complex Histo Dx Primary Tuberculosis Complex Other Test Tuberculosis Pleurisy Primary ProgTuberculosis Uns Exam Tuberculosis Pleurisy Primary ProgTuberculosis No Exam Tuberculosis Pleurisy Primary ProgTuberculosis Exam Unk Tuberculosis Pleurisy Primary ProgTuberculosis Micro Dx Tuberculosis Pleurisy Primary ProgTuberculosis Cult Dx Tuberculosis Pleurisy Primary ProgTuberculosis Histo Dx Tuberculosis Pleurisy Primary ProgTuberculosis Oth Test Oth Primary Progressive Tuberculosis Uns Exam Oth Primary Progressive Tuberculosis No Exam Oth Primary Progressive Tuberculosis Exam Unk Oth Primary Progressive Tuberculosis Micro Dx Oth Primary Progressive Tuberculosis Cult Dx Oth Primary Progressive Tuberculosis Histo Dx Oth Primary Progressive Tuberculosis Oth Test Uns Primary Tuberculosis Infection Uns Exam The Degge Group, Ltd. aTNF Switching Study 11 03/08/2016 01091 01092 01093 01094 01095 01096 0110 01100 01101 01102 01103 01104 01105 01106 01110 01111 01112 01113 01114 01115 01116 01120 01121 01122 01123 01124 01125 01126 01130 01131 01132 01133 01134 01135 01136 01140 01141 01142 01143 01144 01145 01146 01150 01151 01152 01153 01154 01155 01156 01160 01161 01162 01163 01164 Uns Primary Tuberculosis Infection No Exam Uns Primary Tuberculosis Infection Exam Unkn Uns Primary Tuberculosis Infection Micro Dx Uns Primary Tuberculosis Infection Cult Dx Uns Primary Tuberculosis Infection Histo Dx Uns Primary Tuberculosis Infection Oth Test Tuberculosis Of Lung Infiltrative Tuberculosis Of Lung Infiltrative Uns Exam Tuberculosis Of Lung Infiltrative No Exam Tuberculosis Of Lung Infiltrative Exam Unkn Tuberculosis Of Lung Infiltrative Micro Dx Tuberculosis Of Lung Infiltrative Cult Dx Tuberculosis Of Lung Infiltrative Histo Dx Tuberculosis Of Lung Infiltrative Oth Test Tuberculosis Of Lung Nodular Uns Exam Tuberculosis Of Lung Nodular No Exam Tuberculosis Of Lung Nodular Exam Unkn Tuberculosis Of Lung Nodular Micro Dx Tuberculosis Of Lung Nodular Cult Dx Tuberculosis Of Lung Nodular Histo Dx Tuberculosis Of Lung Nodular Other Test Tuberculosis Of Lung W Cavitation Uns Exam Tuberculosis Of Lung W Cavitation No Exam Tuberculosis Of Lung W Cavitation Exam Unkn Tuberculosis Of Lung W Cavitation Micro Dx Tuberculosis Of Lung W Cavitation Cult Dx Tuberculosis Of Lung W Cavitation Histo Dx Tuberculosis Of Lung W Cavitation Oth Test Tuberculosis Of Bronchus Uns Exam Tuberculosis Of Bronchus No Exam Tuberculosis Of Bronchus Exam Unkn Tuberculosis Of Bronchus Micro Dx Tuberculosis Of Bronchus Cult Dx Tuberculosis Of Bronchus Histo Dx Tuberculosis Of Bronchus Other Test Tuberculosis Fibrosis Lung Uns Exam Tuberculosis Fibrosis Lung No Exam Tuberculosis Fibrosis Lung Exam Unkn Tuberculosis Fibrosis Lung Micro Dx Tuberculosis Fibrosis Lung Cult Dx Tuberculosis Fibrosis Lung Histo Dx Tuberculosis Fibrosis Lung Other Test Tuberculosis Bronchiectasis Uns Exam Tuberculosis Bronchiectasis No Exam Tuberculosis Bronchiectasis Exam Unkn Tuberculosis Bronchiectasis Micro Dx Tuberculosis Bronchiectasis Cult Dx Tuberculosis Bronchiectasis Histo Dx Tuberculosis Bronchiectasis Other Test Tuberculosis Pneumonia Uns Exam Tuberculosis Pneumonia No Exam Tuberculosis Pneumonia Exam Unkn Tuberculosis Pneumonia Micro Dx Tuberculosis Pneumonia Cult Dx The Degge Group, Ltd. aTNF Switching Study 12 03/08/2016 01165 01166 01170 01171 01172 01173 01174 01175 01176 01180 01181 01182 01183 01184 01185 01186 01190 01191 01192 01193 01194 01195 01196 0120 01200 01201 01202 01203 01204 01205 01206 01210 01211 01212 01213 01214 01215 01216 01220 01221 01222 01223 01224 01225 01226 01230 01231 01232 01233 01234 01235 01236 01280 01281 Tuberculosis Pneumonia Histo Dx Tuberculosis Pneumonia Other Test Tuberculosis Pneumothorax Uns Exam Tuberculosis Pneumothorax No Exam Tuberculosis Pneumothorax Exam Unkn Tuberculosis Pneumothorax Micro Dx Tuberculosis Pneumothorax Cult Dx Tuberculosis Pneumothorax Histo Dx Tuberculosis Pneumothorax Other Test Other Pulmonary Tuberculosis Uns Exam Other Pulmonary Tuberculosis No Exam Other Pulmonary Tuberculosis Exam Unkn Other Pulmonary Tuberculosis Micro Dx Other Pulmonary Tuberculosis Cult Dx Other Pulmonary Tuberculosis Histo Dx Other Pulmonary Tuberculosis Other Test Uns Pulmonary Tuberculosis Uns Exam Uns Pulmonary Tuberculosis No Exam Uns Pulmonary Tuberculosis Exam Unkn Uns Pulmonary Tuberculosis Micro Dx Uns Pulmonary Tuberculosis Cult Dx Uns Pulmonary Tuberculosis Histo Dx Uns Pulmonary Tuberculosis Other Test Tuberculous Pleurisy Tuberculosis Pleurisy Uns Exam Tuberculosis Pleurisy No Exam Tuberculosis Pleurisy Exam Unkn Tuberculosis Pleurisy Micro Dx Tuberculosis Pleurisy Cult Dx Tuberculosis Pleurisy Histo Dx Tuberculosis Pleurisy Other Test Tuberculosis Of Intrathoracic Nodes Uns Exam Tuberculosis Of Intrathoracic Nodes No Exam Tuberculosis Of Intrathoracic Nodes Exam Unkn Tuberculosis Of Intrathoracic Nodes Micro Dx Tuberculosis Of Intrathoracic Nodes Cult Dx Tuberculosis Of Intrathoracic Nodes Histo Dx Tuberculosis Of Intrathoracic Nodes Oth Test Isolated Trach/Bronch Tuberculosis Uns Exam Isolated Trach/Bronch Tuberculosis No Exam Isolated Trach/Bronch Tuberculosis Exam Unkn Isolated Trach/Bronch Tuberculosis Micro Dx Isolated Trach/Bronch Tuberculosis Cult Dx Isolated Trach/Bronch Tuberculosis Histo Dx Isolated Trach/Bronch Tuberculosis Oth Test Tuberculosis Laryngitis Uns Exam Tuberculosis Laryngitis No Exam Tuberculosis Laryngitis Exam Unkn Tuberculosis Laryngitis Micro Dx Tuberculosis Laryngitis Cult Dx Tuberculosis Laryngitis Histo Dx Tuberculosis Laryngitis Other Test Other Respiratory Tuberculosis Uns Exam Other Respiratory Tuberculosis No Exam The Degge Group, Ltd. aTNF Switching Study 13 03/08/2016 01282 01283 01284 01285 01286 0130 01300 01301 01302 01303 01304 01305 01306 01310 01311 01312 01313 01314 01315 01316 01320 01321 01322 01323 01324 01325 01326 01330 01331 01332 01333 01334 01335 01336 01340 01341 01342 01343 01344 01345 01346 01350 01351 01352 01353 01354 01355 01356 01360 01361 01362 01363 01364 01365 Other Respiratory Tuberculosis Exam Unkn Other Respiratory Tuberculosis Micro Dx Other Respiratory Tuberculosis Cult Dx Other Respiratory Tuberculosis Histo Dx Other Respiratory Tuberculosis Other Test Tuberculous Meningitis Tuberculosis Meningitis Uns Exam Tuberculosis Meningitis No Exam Tuberculosis Meningitis Exam Unkn Tuberculosis Meningitis Micro Dx Tuberculosis Meningitis Cult Dx Tuberculosis Meningitis Histo Dx Tuberculosis Meningitis Other Test Tuberculoma Of Meninges Uns Exam Tuberculoma Of Meninges No Exam Tuberculoma Of Meninges Exam Unkn Tuberculoma Of Meninges Micro Dx Tuberculoma Of Meninges Cult Dx Tuberculoma Of Meninges Histo Dx Tuberculoma Of Meninges Oth Test Tuberculoma Of Brain Uns Exam Tuberculoma Of Brain No Exam Tuberculoma Of Brain Exam Unkn Tuberculoma Of Brain Micro Dx Tuberculoma Of Brain Cult Dx Tuberculoma Of Brain Histo Dx Tuberculoma Of Brain Oth Test Tuberculosis Abscess Of Brain Uns Exam Tuberculosis Abscess Of Brain No Exam Tuberculosis Abscess Of Brain Exam Unkn Tuberculosis Abscess Of Brain Micro Dx Tuberculosis Abscess Of Brain Cult Dx Tuberculosis Abscess Of Brain Histo Dx Tuberculosis Abscess Of Brain Other Test Tuberculoma Of Spinal Cord Uns Exam Tuberculoma Of Spinal Cord No Exam Tuberculoma Of Spinal Cord Exam Unk Tuberculoma Of Spinal Cord Micro Dx Tuberculoma Of Spinal Cord Cult Dx Tuberculoma Of Spinal Cord Histo Dx Tuberculoma Of Spinal Cord Oth Test Tuberculosis Abscess Of Spinal Cord Uns Exam Tuberculosis Abscess Of Spinal Cord No Exam Tuberculosis Abscess Of Spinal Cord Exam Unkn Tuberculosis Abscess Of Spinal Cord Micro Dx Tuberculosis Abscess Of Spinal Cord Cult Dx Tuberculosis Abscess Of Spinal Cord Histo Dx Tuberculosis Abscess Of Spinal Cord Oth Test Tuberculosis Encephalitis/Myelitis Uns Exam Tuberculosis Encephalitis/Myelitis No Exam Tuberculosis Encephalitis/Myelitis Exam Unkn Tuberculosis Encephalitis/Myelitis Micro Dx Tuberculosis Encephalitis/Myelitis Cult Dx Tuberculosis Encephalitis/Myelitis Histo Dx The Degge Group, Ltd. aTNF Switching Study 14 03/08/2016 01366 01380 01381 01382 01383 01384 01385 01386 01390 01391 01392 01393 01394 01395 01396 0140 01400 01401 01402 01403 01404 01405 01406 01480 01481 01482 01483 01484 01485 01486 0150 01500 01501 01502 01503 01504 01505 01506 01510 01511 01512 01513 01514 01515 01516 01520 01521 01522 01523 01524 01525 01526 01550 01551 Tuberculosis Encephalitis/Myelitis Oth Test Other Tuberculosis Cent Nerv Sys Uns Exam Other Tuberculosis Cent Nerv Sys No Exam Other Tuberculosis Cent Nerv Sys Exam Unkn Other Tuberculosis Cent Nerv Sys Micro Dx Other Tuberculosis Cent Nerv Sys Cult Dx Other Tuberculosis Cent Nerv Sys Histo Dx Other Tuberculosis Cent Nerv Sys Oth Test Uns Tuberculosis Cent Nerv Sys Uns Exam Uns Tuberculosis Cent Nerv Sys No Exam Uns Tuberculosis Cent Nerv Sys Exam Unkn Uns Tuberculosis Cent Nerv Sys Micro Dx Uns Tuberculosis Cent Nerv Sys Cult Dx Uns Tuberculosis Cent Nerv Sys Histo Dx Uns Tuberculosis Cent Nerv Sys Other Test Tuberculous Peritonitis Tuberculosis Peritonitis Uns Exam Tuberculosis Peritonitis No Exam Tuberculosis Peritonitis Exam Unkn Tuberculosis Peritonitis Micro Dx Tuberculosis Peritonitis Cult Dx Tuberculosis Peritonitis Histo Dx Tuberculosis Peritonitis Other Test Oth Tuberculosis Perit/Mesen Gland Uns Exam Oth Tuberculosis Perit/Mesen Glands No Exam Oth Tuberculosis Perit/Mesen Gland Exam Unkn Oth Tuberculosis Perit/Mesen Gland Micro Dx Oth Tuberculosis Perit/Mesen Gland Cult Dx Oth Tuberculosis Perit/Mesen Gland Histo Dx Oth Tuberculosis Perit/Mesen Gland Oth Test Tuberculosis Of Vertebral Column Tuberculosis Of Vertebral Column Uns Exam Tuberculosis Of Vertebral Column No Exam Tuberculosis Of Vertebral Column Exam Unkn Tuberculosis Of Vertebral Column Micro Dx Tuberculosis Of Vertebral Column Cult Dx Tuberculosis Of Vertebral Column Histo Dx Tuberculosis Of Vertebral Column Oth Test Tuberculosis Of Hip Uns Exam Tuberculosis Of Hip No Exam Tuberculosis Of Hip Exam Unkn Tuberculosis Of Hip Micro Dx Tuberculosis Of Hip Cult Dx Tuberculosis Of Hip Histo Dx Tuberculosis Of Hip Other Test Tuberculosis Of Knee Uns Exam Tuberculosis Of Knee No Exam Tuberculosis Of Knee Exam Unkn Tuberculosis Of Knee Micro Dx Tuberculosis Of Knee Cult Dx Tuberculosis Of Knee Histo Dx Tuberculosis Of Knee Other Test Tuberculosis Of Limb Bones Uns Exam Tuberculosis Of Limb Bones No Exam The Degge Group, Ltd. aTNF Switching Study 15 03/08/2016 01552 01553 01554 01555 01556 01560 01561 01562 01563 01564 01565 01566 01570 01571 01572 01573 01574 01575 01576 01580 01581 01582 01583 01584 01585 01586 01590 01591 01592 01593 01594 01595 01596 0160 01600 01601 01602 01603 01604 01605 01606 01610 01611 01612 01613 01614 01615 01616 01620 01621 01622 01623 01624 01625 Tuberculosis Of Limb Bones Exam Unkn Tuberculosis Of Limb Bones Micro Dx Tuberculosis Of Limb Bones Cult Dx Tuberculosis Of Limb Bones Histo Dx Tuberculosis Of Limb Bones Other Test Tuberculosis Of Mastoid Uns Exam Tuberculosis Of Mastoid No Exam Tuberculosis Of Mastoid Exam Unkn Tuberculosis Of Mastoid Micro Dx Tuberculosis Of Mastoid Cult Dx Tuberculosis Of Mastoid Histo Dx Tuberculosis Of Mastoid Other Test Tuberculosis Of Other Bone Uns Exam Tuberculosis Of Other Bone No Exam Tuberculosis Of Other Bone Exam Unkn Tuberculosis Of Other Bone Micro Dx Tuberculosis Of Other Bone Cult Dx Tuberculosis Of Other Bone Histo Dx Tuberculosis Of Other Bone Oth Test Tuberculosis Of Other Joint Uns Exam Tuberculosis Of Other Joint No Exam Tuberculosis Of Other Joint Exam Unkn Tuberculosis Of Other Joint Micro Dx Tuberculosis Of Other Joint Cult Dx Tuberculosis Of Other Joint Histo Dx Tuberculosis Of Other Joint Oth Test Tuberculosis Of Uns Bones/Joints Uns Exam Tuberculosis Of Uns Bones/Joints No Exam Tuberculosis Of Uns Bones/Joints Exam Unkn Tuberculosis Of Uns Bones/Joints Micro Dx Tuberculosis Of Uns Bones/Joints Cult Dx Tuberculosis Of Uns Bones/Joints Histo Dx Tuberculosis Of Uns Bones/Joints Other Test Tuberculosis Of Kidney Tuberculosis Of Kidney Uns Exam Tuberculosis Of Kidney No Exam Tuberculosis Of Kidney Exam Unkn Tuberculosis Of Kidney Micro Dx Tuberculosis Of Kidney Cult Dx Tuberculosis Of Kidney Histo Dx Tuberculosis Of Kidney Other Test Tuberculosis Of Bladder Uns Exam Tuberculosis Of Bladder No Exam Tuberculosis Of Bladder Exam Unkn Tuberculosis Of Bladder Micro Dx Tuberculosis Of Bladder Cult Dx Tuberculosis Of Bladder Histo Dx Tuberculosis Of Bladder Other Test Tuberculosis Of Ureter Uns Exam Tuberculosis Of Ureter No Exam Tuberculosis Of Ureter Exam Unkn Tuberculosis Of Ureter Micro Dx Tuberculosis Of Ureter Cult Dx Tuberculosis Of Ureter Histo Dx The Degge Group, Ltd. aTNF Switching Study 16 03/08/2016 01626 01630 01631 01632 01633 01634 01635 01636 01640 01641 01642 01643 01644 01645 01646 01650 01651 01652 01653 01654 01655 01656 01660 01661 01662 01663 01664 01665 01666 01670 01671 01672 01673 01674 01675 01676 01690 01691 01692 01693 01694 01695 01696 0170 01700 01701 01702 01703 01704 01705 01706 01710 01711 01712 Tuberculosis Of Ureter Other Test Tuberculosis Of Oth Urinary Organs Uns Exam Tuberculosis Of Oth Urinary Organs No Exam Tuberculosis Of Oth Urinary Organs Exam Unkn Tuberculosis Of Oth Urinary Organs Micro Dx Tuberculosis Of Oth Urinary Organs Cult Dx Tuberculosis Of Oth Urinary Organs Histo Dx Tuberculosis Of Oth Urinary Organs Oth Test Tuberculosis Of Epididymis Uns Exam Tuberculosis Of Epididymis No Exam Tuberculosis Of Epididymis Exam Unkn Tuberculosis Of Epididymis Micro Dx Tuberculosis Of Epididymis Cult Dx Tuberculosis Of Epididymis Histo Dx Tuberculosis Of Epididymis Other Test Tuberculosis Of Oth Male Gen Organs Uns Exam Tuberculosis Of Oth Male Gen Organs No Exam Tuberculosis Of Oth Male Gen Organs Exam Unkn Tuberculosis Of Oth Male Gen Organs Micro Dx Tuberculosis Of Oth Male Gen Organs Cult Dx Tuberculosis Of Oth Male Gen Organs Histo Dx Tuberculosis Of Oth Male Gen Organs Oth Test Tuberculosis Oophoritis/Salpingitis Uns Exam Tuberculosis Oophoritis/Salpingitis No Exam Tuberculosis Oophoritis/Salpingitis Exam Unkn Tuberculosis Oophoritis/Salpingitis Micro Dx Tuberculosis Oophoritis/Salpingitis Cult Dx Tuberculosis Oophoritis/Salpingitis Histo Dx Tuberculosis Oophoritis/Salpingitis Oth Test Tuberculosis Of Oth Fem Gen Organs Uns Exam Tuberculosis Of Oth Fem Gen Organs No Exam Tuberculosis Of Oth Fem Gen Organs Exam Unkn Tuberculosis Of Oth Fem Gen Organs Micro Dx Tuberculosis Of Oth Fem Gen Organs Cult Dx Tuberculosis Of Oth Fem Gen Organs Histo Dx Tuberculosis Of Oth Fem Gen Organs Oth Test Uns Genitourinary Tuberculosis Of Uns Exam Uns Genitourinary Tuberculosis Of No Exam Uns Genitourinary Tuberculosis Of Exam Unkn Uns Genitourinary Tuberculosis Of Micro Dx Uns Genitourinary Tuberculosis Of Cult Dx Uns Genitourinary Tuberculosis Of Histo Dx Uns Genitourinary Tuberculosis Of Oth Test Tuberculosis Skin And Subcutaneous Tissue Tuberculosis Of Skin/Subq Cellular Uns Exam Tuberculosis Of Skin Subq Cellular No Exam Tuberculosis Of Skin Subq Cellular Exam Unkn Tuberculosis Of Skin Subq Cellular Micro Dx Tuberculosis Of Skin Subq Cellular Cult Dx Tuberculosis Of Skin Subq Cellular Histo Dx Tuberculosis Of Skin Subq Cellular Oth Test Tuberculosis Erythema Nod W Hypsens Uns Exam Tuberculosis Erythema Nod W Hypsens No Exam Tuberculosis Erythema Nod W Hypsens Exam Unkn The Degge Group, Ltd. aTNF Switching Study 17 03/08/2016 01713 01714 01715 01716 01720 01721 01722 01723 01724 01725 01726 01730 01731 01732 01733 01734 01735 01736 01740 01741 01742 01743 01744 01745 01746 01750 01751 01752 01753 01754 01755 01756 01760 01761 01762 01763 01764 01765 01766 01770 01771 01772 01773 01774 01775 01776 01780 01781 01782 01783 01784 01785 01786 01790 Tuberculosis Erythema Nod W Hypsens Micro Dx Tuberculosis Erythema Nod W Hypsens Cult Dx Tuberculosis Erythema Nod W Hypsens Histo Dx Tuberculosis Erythema Nod W Hypsens Oth Test Tuberculosis Peripheral Lymph Nodes Uns Exam Tuberculosis Peripheral Lymph Nodes No Exam Tuberculosis Peripheral Lymph Nodes Exam Unkn Tuberculosis Peripheral Lymph Nodes Micro Dx Tuberculosis Peripheral Lymph Nodes Cult Dx Tuberculosis Peripheral Lymph Nodes Histo Dx Tuberculosis Peripheral Lymph Nodes Oth Test Tuberculosis Of Eye Unspec Tuberculosis Of Eye No Exam Tuberculosis Of Eye Exam Unkn Tuberculosis Of Eye Micro Dx Tuberculosis Of Eye Cult Dx Tuberculosis Of Eye Histo Dx Tuberculosis Of Eye Ot Test Tuberculosis Of Ear Unspec Tuberculosis Of Ear No Exam Tuberculosis Of Ear Exam Unkn Tuberculosis Of Ear Micro Dx Tuberculosis Of Ear Cult Dx Tuberculosis Of Ear Histo Dx Tuberculosis Of Ear Ot Test Tuberculosis Of Thyroid Gland Uns Exam Tuberculosis Of Thyroid Gland No Exam Tuberculosis Of Thyroid Gland Exam Unkn Tuberculosis Of Thyroid Gland Micro Dx Tuberculosis Of Thyroid Gland Cult Dx Tuberculosis Of Thyroid Gland Histo Dx Tuberculosis Of Thyroid Gland Other Test Tuberculosis Of Adrenal Glands Uns Exam Tuberculosis Of Adrenal Glands No Exam Tuberculosis Of Adrenal Glands Exam Unkn Tuberculosis Of Adrenal Glands Micro Dx Tuberculosis Of Adrenal Glands Cult Dx Tuberculosis Of Adrenal Glands Histo Dx Tuberculosis Of Adrenal Glands Other Test Tuberculosis Of Spleen Uns Exam Tuberculosis Of Spleen No Exam Tuberculosis Of Spleen Exam Unkn Tuberculosis Of Spleen Micro Dx Tuberculosis Of Spleen Cult Dx Tuberculosis Of Spleen Histo Dx Tuberculosis Of Spleen Other Test Tuberculosis Of Esophagus Uns Exam Tuberculosis Of Esophagus No Exam Tuberculosis Of Esophagus Exam Unkn Tuberculosis Of Esophagus Micro Dx Tuberculosis Of Esophagus Cult Dx Tuberculosis Of Esophagus Histo Dx Tuberculosis Of Esophagus Other Test Tuberculosis Of Other Organs Uns Exam The Degge Group, Ltd. aTNF Switching Study 18 03/08/2016 01791 01792 01793 01794 01795 01796 0180 01800 01801 01802 01803 01804 01805 01806 01880 01881 01882 01883 01884 01885 01886 01890 01891 01892 01893 01894 01895 01896 0310 0312 039 0390 0391 0392 0393 0394 0398 0399 0461 0463 053 0530 0531 05310 05311 05312 05313 05314 05319 0532 05320 05321 05322 05329 Tuberculosis Of Other Organs No Exam Tuberculosis Of Other Organs Exam Unkn Tuberculosis Of Other Organs Micro Dx Tuberculosis Of Other Organs Cult Dx Tuberculosis Of Other Organs Histo Dx Tuberculosis Of Other Organs Oth Test Acute Miliary Tuberculosis Acute Miliary Tuberculosis Uns Exam Acute Miliary Tuberculosis No Exam Acute Miliary Tuberculosis Exam Unkn Acute Miliary Tuberculosis Micro Dx Acute Miliary Tuberculosis Cult Dx Acute Miliary Tuberculosis Histo Dx Acute Miliary Tuberculosis Other Test Other Miliary Tuberculosis Uns Exam Other Miliary Tuberculosis No Exam Other Miliary Tuberculosis Exam Unkn Other Miliary Tuberculosis Micro Dx Other Miliary Tuberculosis Cult Dx Other Miliary Tuberculosis Histo Dx Other Miliary Tuberculosis Oth Test Uns Miliary Tuberculosis Uns Exam Uns Miliary Tuberculosis No Exam Uns Miliary Tuberculosis Exam Unkn Uns Miliary Tuberculosis Micro Dx Uns Miliary Tuberculosis Cult Dx Uns Miliary Tuberculosis Histo Dx Uns Miliary Tuberculosis Other Test Pulmonary Diseases Other Mycobact Disseminated Mycobacterium Actinomycotic Infections Cutaneous Actinomycotic Infection Pulmonary Actinomycotic Infection Abdominal Actinomycotic Infection Cervicofacial Actinomycotic Infect Madura Foot Actinomycotic Infect Actinomycotic Infection Other Sites Actinomycotic Infection Uns Site Jakob Creutzfeldt Disease Prog Multifocal Leukoencephalopathy Herpes Zoster Herpes Zoster W Meningitis Herpes Zoster W Nerv System Compli Herpes Zoster W Uns Nervous Compl Geniculate Herpes Zoster Postherpetic Trigeminal Neuralgia Postherpetic Polyneuropathy Herpes Zoster Myelitis Herpes Zoster W Oth Nervous Compli Herpes Zoster W Ophthalmic Complic Herpes Zoster Dermatitis Eyelid Herpes Zoster Keratoconjunctivitis Herpes Zoster Iridocyclitis Herpes Zoster W Oth Ophthalmic Comp The Degge Group, Ltd. aTNF Switching Study 19 03/08/2016 0537 05371 05379 0538 0539 054 0540 0541 05410 05411 05412 05413 05419 0542 0543 0544 05440 05441 05442 05443 05444 05449 0545 0546 0547 05471 05472 05473 05474 05479 0548 0549 059 0588 0590 0591 0592 0598 0599 07041 07044 07051 07054 07070 07071 0780 0781 07810 07811 07819 0785 0794 090 0900 Herpes Zoster W Other Complications Otitis External Herpes Zoster Herpes Zoster W Other Complications Herpes Zoster W Uns Complication Herpes Zoster Wo Complication Herpes Simplex Eczema Herpeticum Genital Herpes Genital Herpes Unspec Herpetic Vulvovaginitis Herpetic Ulceration Vulva Herpetic Infection Penis Other Genital Herpes Herpetic Gingivostomatitis Herpetic Meningoencephalitis Herpes Simplex W Ophthalmic Complic Herpes Simp W Uns Ophthalmic Compl Herpes Simplex Dermatitis Eyelid Herpes Simplex Dendritic Keratitis Herpes Simplex Disciform Keratitis Herpes Simplex Iridocyclitis Herpes Simp W Oth Ophthalmic Compli Herpetic Septicemia Herpetic Whitlow Herpes Simplex W Other Complication Visceral Herpes Simplex Herpes Simplex Meningitis Herpes Simplex Otitis Externa Herpes Simplex Myelitis Herpes Simplex W Other Compli Herpes Simplex W Uns Compli Herpes Simplex Wo Compli Other poxvirus infections Other human herpesvirus infection Other orthopoxvirus infections Other parapoxvirus infections Yatapoxvirus infections Other poxvirus infections Poxvirus infections, unspecified Acute Hepatitis C W Hepatic Coma Chr Hepatitis C W Coma Acute Hepatitis C Wo Hep Coma Chr Hepatitis C Wo Coma Uns Viral Hepatitis C Wo Coma Uns Viral Hepatitis C W Coma Molluscum Contagiosum Viral Warts Viral Warts Unspecified Condyloma Acuminatum Other Specified Viral Warts Cytomegaloviral Disease Human Papilloma Virus Infection Congenital Syphilis Early Congenital Syphilis Sympt The Degge Group, Ltd. aTNF Switching Study 20 03/08/2016 0901 0902 0903 0904 09040 09041 09042 09049 0905 0906 0907 0909 091 0910 0911 0912 0913 0914 0915 09151 09152 0916 09161 09162 09169 0917 0918 09181 09182 09189 0919 092 0920 0929 093 0930 0931 0932 09320 09321 09322 09323 09324 0938 09381 09382 09389 0939 094 0940 0941 0942 0943 0948 Early Congenital Syphilis Latent Uns Early Congenital Syphilis Syphilitic Interstitial Keratitis Juvenile Neurosyphilis Uns Juvenile Neurosyphilis Congenital Syphilitic Encephalitis Congenital Syphilitic Meningitis Oth Juvenile Neurosyphilis Oth Late Congenital Syphilis Sympt Late Congenital Syphilis Latent Uns Late Congenital Syphilis Congenital Syphilis Unspec Early Syphilis Symptomatic Genital Syphilis Primary Anal Syphilis Other Primary Syphilis Secondary Syphilis Skin/Mucous Memb Adenopathy Secondary Syphilis Uveitis Due To Secondary Syphilis Syphilitic Chorioretinitis Syphilitic Iridocyclitis Secondary Syphilis Of Viscera/Bone Secondary Syphilitic Periostitis Secondary Syphilitic Hepatitis Secondary Syphilis Oth Viscera Secondary Syphilis Relapse Other Forms Of Secondary Syphilis Acute Syphilitic Meningitis Syphilitic Alopecia Oth Forms Secondary Syphilis Uns Secondary Syphilis Early Syphilis Latent Early Syphilis Latent W Relapse Uns Early Syphilis Latent Cardiovascular Syphilis Aneurysm Aorta Syphilitic Syphilitic Aortitis Syphilitic Endocarditis Uns Syphilitic Endocarditis Valve Syphilitic Mitral Valve Syphilitic Aortic Valve Syphilitic Tricuspid Valve Syphilitic Pulmonary Valve Other Cardiovascular Syphilis Syphilitic Pericarditis Syphilitic Myocarditis Other Cardiovascular Syphilis Uns Cardiovascular Syphilis Neurosyphilis Tabes Dorsalis General Paresis Syphilitic Meningitis Asymptomatic Neurosyphilis Other Specified Neurosyphilis The Degge Group, Ltd. aTNF Switching Study 21 03/08/2016 09481 09482 09483 09484 09485 09486 09487 09489 0949 095 0950 0951 0952 0953 0954 0955 0956 0957 0958 0959 096 097 0970 0971 0979 1101 112 1120 1121 1122 1123 1124 1125 1128 11281 11282 11283 11284 11285 11289 1129 114 1140 1141 1142 1143 1144 1145 1149 115 1150 11500 11501 11502 Syphilitic Encephalitis Syphilitic Parkinsonism Syphilitic Dissem Retinochoroiditis Syphilitic Optic Atrophy Syphilitic Retrobulbar Neuritis Syphilitic Acoustic Neuritis Syphilitic Rupt Cerebral Aneurysm Other Specified Neurosyphilis Neurosyphilis Unspecified Other Late Syphilis With Symptoms Syphilitic Episcleritis Syphilis Lung Syphilitic Peritonitis Syphilis Liver Syphilis Kidney Syphilis Bone Syphilis Muscle Syphilis Synovium/Tendon/Bursa Other Forms Late Sympt Syphilis Uns Late Symptomatic Syphilis Late Syphilis Latent Other And Unspecified Syphilis Late Syphilis Unspecified Latent Syphilis Unspecified Syphilis Unspecified Dermatophytosis Nail Candidiasis Candidiasis Mouth Candidiasis Vulva/Vagina Candidiasis Ot Urogenital Sites Candidiasis Skin/Nails Candidiasis Lung Disseminated Candidiasis Candidiasis Other Sites Candidal Endocarditis Candidal Otitis Externa Candidal Meningitis Candidal Esophagitis Candidal Enteritis Candidiasis Other Sites Candidiasis Uns Site Coccidioidomycosis Primary Coccidioidomycosis Prim Extrapulm Coccidioidomycosis Coccidioidal Meningitis Ot Prog Coccidioidomycosis Chr Pulm Coccidioidomycosis Uns Pulm Coccidioidomycosis Coccidioidomycosis Unspec Histoplasmosis Infection Histoplasma Capsulatum Histoplasma Capsulat Infec Wo Manif Histoplasma Capsulat Meningitis Histoplasma Capsulat Retinitis The Degge Group, Ltd. aTNF Switching Study 22 03/08/2016 11503 11504 11505 11509 1151 11510 11511 11512 11513 11514 11515 11519 1159 11590 11591 11592 11593 11594 11595 11599 116 1160 1161 1162 1173 1174 1175 118 1288 130 1300 1301 1302 1303 1304 1305 1307 1308 1309 1362 1363 1368 176 1760 1761 1762 1763 1764 1765 1768 1769 3210 37005 481 Histoplasma Capsulat Pericarditis Histoplasma Capsulat Endocarditis Histoplasma Capsulat Pneonia Histoplasma Capsulat W Oth Manif Infection By Histoplasma Duboisii Histoplasma Dub Infection Wo Manif Histoplasma Dub Meningitis Histoplasma Dub Retinitis Histoplasma Dub Pericarditis Histoplasma Dub Endocarditis Histoplasma Dub Pneumonia Histoplasma Dub Infect W Oth Manif Histoplasmosis Unspecified Uns Histoplasmosis Wo Manifestation Uns Histoplasmosis Meningitis Uns Histoplasmosis Retinitis Uns Histoplasmosis Pericarditis Uns Histoplasmosis Endocarditis Uns Histoplasmosis Pneumonia Uns Histoplasmosis W Oth Manif Blastomycotic Infection Blastomycosis Paracoccidioidomycosis Lobomycosis Aspergillosis Mycotic Mycetomas Cryptococcosis Opportunistic Mycoses Other specified helminthiasis Toxoplasmosis Meningoencephalitis Toxoplasmosis Conjunctivitis Toxoplasmosis Chorioretinitis Toxoplasmosis Myocarditis Toxoplasmosis Pneumonitis Toxoplasmosis Hepatitis Toxoplasmosis Toxoplasmosis Other Sites Multisystemic Dissem Toxoplasmosis Toxoplasmosis Unspecified Free Living Amebae Infections Pneumocystosis Other Infectious/Parasitic Diseases Kaposi's Sarcoma Kaposi's Sarcoma Skin Kaposi's Sarcoma Soft Tissue Kaposi's Sarcoma Palate Kaposi's Sarcoma Gastrointestinal Kaposi's Sarcoma Lung Kaposi's Sarcoma Lymph Nodes Kaposi's Sarcoma Other Sites Kaposi's Sarcoma Site Unspec Cryptococcal Meningitis Mycotic Corneal Ulcer Pneumococcal Pneumonia The Degge Group, Ltd. aTNF Switching Study 23 03/08/2016 482 4820 4821 4822 4823 48230 48231 48232 48239 4824 48240 48241 48249 4828 48281 48282 48283 48284 48289 4829 4830 4846 4847 5186 5286 Other Bacterial Pneumonia Pneumonia Klebsiella Pneumoniae Pneumonia Pseudomonas Pneumonia Hemophilus Influenzae Pneumonia Due To Streptococcus Pneumonia Uns Streptococcus Pneumonia Streptococcus Group A Pneumonia Streptococcus Group B Pneumonia Oth Streptococcus Pneumonia Due To Staphylococcus Pneumonia Uns Staphylococcus Pneumonia Staphlococcus Aureus Oth Staphylococcus Pneumonia Pneumonia Due To Other Bacteria Pneumonia Anaerobes Pneumonia Escherichia Coli Pneumonia Oth Gram Negative Bact Legionnaires' Disease Pneumonia Other Bacteria Uns Bacterial Pneumonia Pneumonia Mycoplasma Pneumoniae Pneumonia Aspergillosis Pneumonia Oth Systemic Mycoses Allergic Bronchopulmonary Aspergill Leukoplakia Oral Mucosa The Degge Group, Ltd. aTNF Switching Study 24 03/08/2016 APPENDIX F. Procedural Codes Used to Define Joint Surgery CPT- 4 Category description Procedures for hand/wrist 25040 Arthrotomy, radiocarpal or midcarpal joint, with exploration, drainage, or removal of foreign body 25085 Capsulotomy, wrist (eg, contracture) 25100 Arthrotomy, wrist joint; with biopsy 25101 Arthrotomy, wrist joint; with joint exploration, with or without biopsy, with or without removal of loose or foreign body 25105 Arthrotomy, wrist joint; with synovectomy 25118 Synovectomy, extensor tendon sheath, wrist, single compartment; 25119 Synovectomy, extensor tendon sheath, wrist, single compartment; with resection of distal ulna Capsulorrhaphy or reconstruction, wrist, open (eg, capsulodesis, ligament repair, tendon transfer or graft) (includes synovectomy, capsulotomy and open 25320 reduction) for carpal instability 25332 Arthroplasty, wrist, with or without interposition, with or without external or internal fixation 25394 Osteoplasty, carpal bone, shortening 25443 Arthroplasty with prosthetic replacement; scaphoid carpal (navicular) 25445 Arthroplasty with prosthetic replacement; trapezium 25446 Arthroplasty with prosthetic replacement; distal radius and partial or entire carpus (total wrist) 25447 Arthroplasty, interposition, intercarpal or carpometacarpal joints 25449 Revision of arthroplasty, including removal of implant, wrist joint 25670 Open treatment of radiocarpal or intercarpal dislocation, one or more bones 25800 Arthrodesis, wrist; complete, without bone graft (includes radiocarpal and/or intercarpal and/or carpometacarpal joints) 25805 Arthrodesis, wrist; with sliding graft 25810 Arthrodesis, wrist; with iliac or other autograft (includes obtaining graft) 25820 Arthrodesis, wrist; limited, without bone graft (eg, intercarpal or radiocarpal) 25825 Arthrodesis, wrist; with autograft (includes obtaining graft) 26070 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; carpometacarpal joint 26075 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; metacarpophalangeal joint, each 26080 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; interphalangeal joint, each 26100 Arthrotomy with biopsy; carpometacarpal joint, each 26105 Arthrotomy with biopsy; metacarpophalangeal joint, each 26110 Arthrotomy with biopsy; interphalangeal joint, each 26130 Synovectomy, carpometacarpal joint The Degge Group, Ltd. aTNF Switching Study 25 03/08/2016 CPT- 4 Category description 26135 26140 26145 26160 26170 26180 26340 26471 26474 26476 26477 26478 26479 26480 26483 26525 26530 26531 26540 26541 26542 26545 26548 26565 26567 26568 26841 26842 26843 26844 26850 26852 26860 Synovectomy, metacarpophalangeal joint including intrinsic release and extensor hood reconstruction, each digit Synovectomy, proximal interphalangeal joint, including extensor reconstruction, each interphalangeal joint Synovectomy, tendon sheath, radical (tenosynovectomy), flexor tendon, palm and/or finger, each tendon Excision of lesion of tendon sheath or joint capsule (eg, cyst, mucous cyst, or ganglion), hand or finger Excision of tendon, palm, flexor or extensor, single, each tendon Excision of tendon, finger, flexor or extensor, each tendon Manipulation, finger joint, under anesthesia, each joint Tenodesis; of proximal interphalangeal joint, each joint Tenodesis; of distal joint, each joint Lengthening of tendon, extensor, hand or finger, each tendon Shortening of tendon, extensor, hand or finger, each tendon Lengthening of tendon, flexor, hand or finger, each tendon Shortening of tendon, flexor, hand or finger, each tendon Transfer or transplant of tendon, carpometacarpal area or dorsum of hand; without free graft, each tendon Transfer or transplant of tendon, carpometacarpal area or dorsum of hand; with free tendon graft (includes obtaining graft), each tendon Capsulectomy or capsulotomy; interphalangeal joint, each joint Arthroplasty, metacarpophalangeal joint; each joint Arthroplasty, metacarpophalangeal joint; with prosthetic implant, each joint Repair of collateral ligament, metacarpophalangeal or interphalangeal joint Reconstruction, collateral ligament, metacarpophalangeal joint, single; with tendon or fascial graft (includes obtaining graft) Reconstruction, collateral ligament, metacarpophalangeal joint, single; with local tissue (eg, adductor advancement) Reconstruction, collateral ligament, interphalangeal joint, single, including graft, each joint Repair and reconstruction, finger, volar plate, interphalangeal joint Osteotomy; metacarpal, each Osteotomy; phalanx of finger, each Osteoplasty, lengthening, metacarpal or phalanx Arthrodesis, carpometacarpal joint, thumb, with or without internal fixation; Arthrodesis, carpometacarpal joint, thumb, with or without internal fixation; with autograft (includes obtaining graft) Arthrodesis, carpometacarpal joint, digit, other than thumb, each; Arthrodesis, carpometacarpal joint, digit, other than thumb, each; with autograft (includes obtaining graft) Arthrodesis, metacarpophalangeal joint, with or without internal fixation; Arthrodesis, metacarpophalangeal joint, with or without internal fixation; with autograft (includes obtaining graft) Arthrodesis, interphalangeal joint, with or without internal fixation; The Degge Group, Ltd. aTNF Switching Study 26 03/08/2016 CPT- 4 Category description Arthrodesis, interphalangeal joint, with or without internal fixation; each additional interphalangeal joint (list separately in addition to code for primary procedure) 26862 Arthrodesis, interphalangeal joint, with or without internal fixation; with autograft (includes obtaining graft) Arthrodesis, interphalangeal joint, with or without internal fixation; with autograft (includes obtaining graft), each additional joint (list separately in addition 26863 to code for primary procedure) 28070 Synovectomy; intertarsal or tarsometatarsal joint, each 28072 Synovectomy; metatarsophalangeal joint, each 28272 Capsulotomy; interphalangeal joint, each joint (separate procedure) 28310 Osteotomy, shortening, angular or rotational correction; proximal phalanx, first toe (separate procedure) 28312 Osteotomy, shortening, angular or rotational correction; other phalanges, any toe 29840 Arthroscopy, wrist, diagnostic, with or without synovial biopsy (separate procedure) 29844 Arthroscopy, wrist, surgical; synovectomy, partial 29845 Arthroscopy, wrist, surgical; synovectomy, complete 29846 Arthroscopy, wrist, surgical; excision and/or repair of triangular fibrocartilage and/or joint debridement 29848 Endoscopy, wrist, surgical, with release of transverse carpal ligament 29900 Arthroscopy, metacarpophalangeal joint, diagnostic, includes synovial biopsy 29901 Arthroscopy, metacarpophalangeal joint, surgical; with debridement 29902 Arthroscopy, metacarpophalangeal joint, surgical; with reduction of displaced ulnar collateral ligament (eg, stenar lesion) Procedures for elbow/shoulder/arm area 23040 Arthrotomy, glenohumeral joint, including exploration, drainage, or removal of foreign body 23044 Arthrotomy, acromioclavicular, sternoclavicular joint, including exploration, drainage, or removal of foreign body 23101 Arthrotomy, acromioclavicular joint or sternoclavicular joint, including biopsy and/or excision of torn cartilage 23105 Arthrotomy; glenohumeral joint, with synovectomy, with or without biopsy 23106 Arthrotomy; sternoclavicular joint, with synovectomy, with or without biopsy 23405 Tenotomy, shoulder area; single tendon 23406 Tenotomy, shoulder area; multiple tendons through same incision 23420 Reconstruction of complete shoulder (rotator) cuff avulsion, chronic (includes acromioplasty) 23465 Capsulorrhaphy, glenohumeral joint, posterior, with or without bone block 23466 Capsulorrhaphy, glenohumeral joint, any type multi-directional instability 23470 Arthroplasty, glenohumeral joint; hemiarthroplasty 23472 Arthroplasty, glenohumeral joint; total shoulder (glenoid and proximal humeral replacement (eg, total shoulder)) 23480 Osteotomy, clavicle, with or without internal fixation; 23485 Osteotomy, clavicle, with or without internal fixation; with bone graft for nonunion or malunion (includes obtaining graft and/or necessary fixation) 23700 Manipulation under anesthesia, shoulder joint, including application of fixation apparatus (dislocation excluded) 26861 The Degge Group, Ltd. aTNF Switching Study 27 03/08/2016 CPT- 4 Category description 23800 23802 24000 24100 24101 24155 24160 24301 24305 24310 24320 24330 24331 24341 24343 24344 24345 24346 24360 24361 24362 24363 24365 24366 24800 24802 25107 25290 Arthrodesis, glenohumeral joint; Arthrodesis, glenohumeral joint; with autogenous graft (includes obtaining graft) Arthrotomy, elbow, including exploration, drainage, or removal of foreign body Arthrotomy, elbow; with synovial biopsy only Arthrotomy, elbow; with joint exploration, with or without biopsy, with or without removal of loose or foreign body Resection of elbow joint (arthrectomy) Implant removal; elbow joint Muscle or tendon transfer, any type, upper arm or elbow, single (excluding 24320-24331) Tendon lengthening, upper arm or elbow, each tendon Tenotomy, open, elbow to shoulder, each tendon Tenoplasty, with muscle transfer, with or without free graft, elbow to shoulder, single (seddon-brookes type procedure) Flexor-plasty, elbow (eg, steindler type advancement); Flexor-plasty, elbow (eg, steindler type advancement); with extensor advancement Repair, tendon or muscle, upper arm or elbow, each tendon or muscle, primary or secondary (excludes rotator cuff) Repair lateral collateral ligament, elbow, with local tissue Reconstruction lateral collateral ligament, elbow, with tendon graft (includes harvesting of graft) Repair medial collateral ligament, elbow, with local tissue Reconstruction medial collateral ligament, elbow, with tendon graft (includes harvesting of graft) Arthroplasty, elbow; with membrane (eg, fascial) Arthroplasty, elbow; with distal humeral prosthetic replacement Arthroplasty, elbow; with implant and fascia lata ligament reconstruction Arthroplasty, elbow; with distal humerus and proximal ulnar prosthetic replacement (eg, total elbow) Arthroplasty, radial head; Arthroplasty, radial head; with implant Arthrodesis, elbow joint; local Arthrodesis, elbow joint; with autogenous graft (includes obtaining graft) Arthrotomy, distal radioulnar joint including repair of triangular cartilage, complex Tenotomy, open, flexor or extensor tendon, forearm and/or wrist, single, each tendon Reconstruction for stabilization of unstable distal ulna or distal radioulnar joint, secondary by soft tissue stabilization (eg, tendon transfer, tendon graft or weave, or tenodesis) with or without open reduction of distal radioulnar joint Osteotomy, radius; distal third Osteoplasty, radius or ulna; shortening Osteoplasty, radius or ulna; lengthening with autograft 25337 25350 25390 25391 The Degge Group, Ltd. aTNF Switching Study 28 03/08/2016 CPT- 4 Category description 25392 Osteoplasty, radius and ulna; shortening (excluding 64876) 25393 Osteoplasty, radius and ulna; lengthening with autograft 25441 Arthroplasty with prosthetic replacement; distal radius 25442 Arthroplasty with prosthetic replacement; distal ulna 25443 Arthroplasty with prosthetic replacement; scaphoid carpal (navicular) 25444 Arthroplasty with prosthetic replacement; lunate 25830 Arthrodesis, distal radioulnar joint with segmental resection of ulna, with or without bone graft (eg, sauve-kapandji procedure) 26060 Tenotomy, percutaneous, single, each digit 26450 Tenotomy, flexor, palm, open, each tendon 26455 Tenotomy, flexor, finger, open, each tendon 26460 Tenotomy, extensor, hand or finger, open, each tendon 27003 Tenotomy, adductor, subcutaneous, open, with obturator neurectomy 27054 Arthrotomy with synovectomy, hip joint 29805 Arthroscopy, shoulder, diagnostic, with or without synovial biopsy (separate procedure) 29806 Arthroscopy, shoulder, surgical; capsulorrhaphy 29807 Arthroscopy, shoulder, surgical; repair of slap lesion 29819 Arthroscopy, shoulder, surgical; with removal of loose body or foreign body 29820 Arthroscopy, shoulder, surgical; synovectomy, partial 29821 Arthroscopy, shoulder, surgical; synovectomy, complete 29822 Arthroscopy, shoulder, surgical; debridement, limited 29823 Arthroscopy, shoulder, surgical; debridement, extensive 29824 Arthroscopy, shoulder, surgical; distal claviculectomy including distal articular surface (mumford procedure) 29825 Arthroscopy, shoulder, surgical; with lysis and resection of adhesions, with or without manipulation 29826 Arthroscopy, shoulder, surgical; decompression of subacromial space with partial acromioplasty, with or without coracoacromial release 29827 Arthroscopy, shoulder, surgical; with rotator cuff repair 29830 Arthroscopy, elbow, diagnostic, with or without synovial biopsy (separate procedure) 29834 Arthroscopy, elbow, surgical; with removal of loose body or foreign body 29835 Arthroscopy, elbow, surgical; synovectomy, partial 29836 Arthroscopy, elbow, surgical; synovectomy, complete 29837 Arthroscopy, elbow, surgical; debridement, limited 29838 Arthroscopy, elbow, surgical; debridement, extensive Procedures for hip area 24301 Muscle or tendon transfer, any type, upper arm or elbow, single (excluding 24320-24331) The Degge Group, Ltd. aTNF Switching Study 29 03/08/2016 CPT- 4 Category description 24400 24420 27000 27001 27005 27006 27033 Osteotomy, humerus, with or without internal fixation Osteoplasty, humerus (eg, shortening or lengthening) (excluding 64876) Tenotomy, adductor of hip, percutaneous (separate procedure) Tenotomy, adductor of hip, open Tenotomy, hip flexor(s), open (separate procedure) Tenotomy, abductors and/or extensor(s) of hip, open (separate procedure) Arthrotomy, hip, including exploration or removal of loose or foreign body Capsulectomy or capsulotomy, hip, with or without excision of heterotopic bone, with release of hip flexor muscles (ie, gluteus medius, gluteus minimus, tensor fascia latae, rectus femoris, sartorius, iliopsoas) Arthrotomy, with biopsy; sacroiliac joint Arthrotomy, with biopsy; hip joint Hemiarthroplasty, hip, partial (eg, femoral stem prosthesis, bipolar arthroplasty) Arthroplasty, acetabular and proximal femoral prosthetic replacement (total hip arthroplasty), with or without autograft or allograft Conversion of previous hip surgery to total hip arthroplasty, with or without autograft or allograft Revision of total hip arthroplasty; both components, with or without autograft or allograft Revision of total hip arthroplasty; acetabular component only, with or without autograft or allograft Revision of total hip arthroplasty; femoral component only, with or without allograft Osteotomy and transfer of greater trochanter of femur (separate procedure) Osteotomy, iliac, acetabular or innominate bone; Osteotomy, iliac, acetabular or innominate bone; with open reduction of hip Osteotomy, iliac, acetabular or innominate bone; with femoral osteotomy Osteotomy, iliac, acetabular or innominate bone; with femoral osteotomy and with open reduction of hip Osteotomy, femoral neck (separate procedure) Manipulation, hip joint, requiring general anesthesia Arthrodesis, hip joint (including obtaining graft); Arthrodesis, hip joint (including obtaining graft); with subtrochanteric osteotomy Osteotomy, femur, shaft or supracondylar; without fixation Osteotomy, femur, shaft or supracondylar; with fixation Osteoplasty, femur; shortening (excluding 64876) Osteoplasty, femur; lengthening Osteoplasty, femur; combined, lengthening and shortening with femoral segment transfer Arthroscopy, hip, diagnostic with or without synovial biopsy (separate procedure) Arthroscopy, hip, surgical; with removal of loose body or foreign body 27036 27050 27052 27125 27130 27132 27134 27137 27138 27140 27146 27147 27151 27156 27161 27275 27284 27286 27448 27450 27465 27466 27468 29860 29861 The Degge Group, Ltd. aTNF Switching Study 30 03/08/2016 CPT- 4 Category description 29862 Arthroscopy, hip, surgical; with debridement/shaving of articular cartilage (chondroplasty), abrasion arthroplasty, and/or resection of labrum 29863 Arthroscopy, hip, surgical; with synovectomy Procedures for knee area 27330 Arthrotomy, knee; with synovial biopsy only 27331 Arthrotomy, knee; including joint exploration, biopsy, or removal of loose or foreign bodies 27332 Arthrotomy, with excision of semilunar cartilage (meniscectomy) knee; medial or lateral 27333 Arthrotomy, with excision of semilunar cartilage (meniscectomy) knee; medial and lateral 27334 Arthrotomy, with synovectomy, knee; anterior or posterior 27335 Arthrotomy, with synovectomy, knee; anterior and posterior including popliteal area 27390 Tenotomy, open, hamstring, knee to hip; single tendon 27391 Tenotomy, open, hamstring, knee to hip; multiple tendons, one leg 27392 Tenotomy, open, hamstring, knee to hip; multiple tendons, bilateral 27403 Arthrotomy with meniscus repair, knee 27427 Ligamentous reconstruction (augmentation), knee; extra-articular 27428 Ligamentous reconstruction (augmentation), knee; intra-articular (open) 27429 Ligamentous reconstruction (augmentation), knee; intra-articular (open) and extra-articular 27435 Capsulotomy, posterior capsular release, knee 27437 Arthroplasty, patella; without prosthesis 27438 Arthroplasty, patella; with prosthesis 27440 Arthroplasty, knee, tibial plateau; 27441 Arthroplasty, knee, tibial plateau; with debridement and partial synovectomy 27442 Arthroplasty, femoral condyles or tibial plateau(s), knee; 27443 Arthroplasty, femoral condyles or tibial plateau(s), knee; with debridement and partial synovectomy 27445 Arthroplasty, knee, hinge prosthesis (eg, walldius type) 27446 Arthroplasty, knee, condyle and plateau; medial or lateral compartment 27447 Arthroplasty, knee, condyle and plateau; medial and lateral compartments with or without patella resurfacing (total knee arthroplasty) 27486 Revision of total knee arthroplasty, with or without allograft; one component 27487 Revision of total knee arthroplasty, with or without allograft; femoral and entire tibial component 27570 Manipulation of knee joint under general anesthesia (includes application of traction or other fixation devices) 27580 Arthrodesis, knee, any technique 27712 Osteotomy; multiple, with realignment on intramedullary rod (eg, sofield type procedure) 27715 Osteoplasty, tibia and fibula, lengthening or shortening 27871 Arthrodesis, tibiofibular joint, proximal or distal The Degge Group, Ltd. aTNF Switching Study 31 03/08/2016 CPT- 4 Category description 29866 29867 29868 29870 29873 29874 29875 29876 29877 29879 29880 29881 29882 29883 29884 Arthroscopy, knee, surgical; osteochondral autograft(s) (eg, mosaicplasty) (includes harvesting of the autograft) Arthroscopy, knee, surgical; osteochondral allograft (eg, mosaicplasty) Arthroscopy, knee, surgical; meniscal transplantation (includes arthrotomy for meniscal insertion), medial or lateral Arthroscopy, knee, diagnostic, with or without synovial biopsy (separate procedure) Arthroscopy, knee, surgical; with lateral release Arthroscopy, knee, surgical; for removal of loose body or foreign body (eg, osteochondritis dissecans fragmentation, chondral fragmentation) Arthroscopy, knee, surgical; synovectomy, limited (eg, plica or shelf resection) (separate procedure) Arthroscopy, knee, surgical; synovectomy, major, two or more compartments (eg, medial or lateral) Arthroscopy, knee, surgical; debridement/shaving of articular cartilage (chondroplasty) Arthroscopy, knee, surgical; abrasion arthroplasty (includes chondroplasty where necessary) or multiple drilling or microfracture Arthroscopy, knee, surgical; with meniscectomy (medial and lateral, including any meniscal shaving) Arthroscopy, knee, surgical; with meniscectomy (medial or lateral, including any meniscal shaving) Arthroscopy, knee, surgical; with meniscus repair (medial or lateral) Arthroscopy, knee, surgical; with meniscus repair (medial and lateral) Arthroscopy, knee, surgical; with lysis of adhesions, with or without manipulation (separate procedure) Arthroscopy, knee, surgical; drilling for osteochondritis dissecans with bone grafting, with or without internal fixation (including debridement of base of 29885 lesion) 29886 Arthroscopy, knee, surgical; drilling for intact osteochondritis dissecans lesion 29887 Arthroscopy, knee, surgical; drilling for intact osteochondritis dissecans lesion with internal fixation Procedures for ankle/foot joints 26535 Arthroplasty, interphalangeal joint; each joint 26536 Arthroplasty, interphalangeal joint; with prosthetic implant, each joint 27605 Tenotomy, percutaneous, achilles tendon (separate procedure); local anesthesia 27606 Tenotomy, percutaneous, achilles tendon (separate procedure); general anesthesia 27610 Arthrotomy, ankle, including exploration, drainage, or removal of foreign body 27612 Arthrotomy, posterior capsular release, ankle, with or without achilles tendon lengthening 27620 Arthrotomy, ankle, with joint exploration, with or without biopsy, with or without removal of loose or foreign body 27625 Arthrotomy, with synovectomy, ankle; 27626 Arthrotomy, with synovectomy, ankle; including tenosynovectomy 27700 Arthroplasty, ankle; 27702 Arthroplasty, ankle; with implant (total ankle) 27703 Arthroplasty, ankle; revision, total ankle 27870 Arthrodesis, ankle, open The Degge Group, Ltd. aTNF Switching Study 32 03/08/2016 CPT- 4 Category description 28010 28011 28020 28022 28024 28050 28052 28054 28070 28086 28088 28090 28092 28230 28232 28234 28260 28261 28262 28264 28270 28302 28304 28305 28306 28307 28308 28309 28313 28705 28715 28725 28730 Tenotomy, percutaneous, toe; single tendon Tenotomy, percutaneous, toe; multiple tendons Arthrotomy, including exploration, drainage, or removal of loose or foreign body; intertarsal or tarsometatarsal jt Arthrotomy, including exploration, drainage, or removal of loose or foreign body; metatarsophalangeal joint Arthrotomy, including exploration, drainage, or removal of loose or foreign body; interphalangeal joint Arthrotomy with biopsy; intertarsal or tarsometatarsal joint Arthrotomy with biopsy; metatarsophalangeal joint Arthrotomy with biopsy; interphalangeal joint Synovectomy; intertarsal or tarsometatarsal joint, each Synovectomy, tendon sheath, foot; flexor Synovectomy, tendon sheath, foot; extensor Excision of lesion, tendon, tendon sheath, or capsule (including synovectomy) (eg, cyst or ganglion); foot Excision of lesion, tendon, tendon sheath, or capsule (including synovectomy) (eg, cyst or ganglion); toe(s), each Tenotomy, open, tendon flexor; foot, single or multiple tendon(s) (separate procedure) Tenotomy, open, tendon flexor; toe, single tendon (separate procedure) Tenotomy, open, extensor, foot or toe, each tendon Capsulotomy, midfoot; medial release only (separate procedure) Capsulotomy, midfoot; with tendon lengthening Capsulotomy, midfoot; extensive, including posterior talotibial capsulotomy and tendon(s) lengthening (eg, resistant clubfoot deformity) Capsulotomy, midtarsal (eg, heyman type procedure) Capsulotomy; metatarsophalangeal joint, with or without tenorrhaphy, each joint (separate procedure) Osteotomy; talus Osteotomy, tarsal bones, other than calcaneus or talus; Osteotomy, tarsal bones, other than calcaneus or talus; with autograft (includes obtaining graft) (eg, fowler type) Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; first metatarsal Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; first metatarsal with autograft (other than first toe) Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; other than first metatarsal, each Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; multiple (eg, swanson type cavus foot procedure) Reconstruction, angular deformity of toe, soft tissue procedures only (eg, overlapping second toe, fifth toe, curly toes) Arthrodesis; pantalar Arthrodesis; triple Arthrodesis; subtalar Arthrodesis, midtarsal or tarsometatarsal, multiple or transverse; The Degge Group, Ltd. aTNF Switching Study 33 03/08/2016 CPT- 4 Category description 28735 Arthrodesis, midtarsal or tarsometatarsal, multiple or transverse; with osteotomy (eg, flatfoot correction) 28737 Arthrodesis, with tendon lengthening and advancement, midtarsal, tarsal navicular-cuneiform (eg, miller type procedure) 28740 Arthrodesis, midtarsal or tarsometatarsal, single joint 28755 Arthrodesis, great toe; interphalangeal joint 28760 Arthrodesis, with extensor hallucis longus transfer to first metatarsal neck, great toe, interphalangeal joint (eg, jones type procedure) 29891 Arthroscopy, ankle, surgical, excision of osteochondral defect of talus and/or tibia, including drilling of the defect 29894 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; with removal of loose body or foreign body 29895 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; synovectomy, partial 29897 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; debridement, limited 29898 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; debridement, extensive 29899 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; with ankle arthrodesis Procedures for lumbar/spine/jaw/other 21010 21240 21242 21243 22210 22212 22214 22216 22220 22222 22224 22226 22532 22533 22534 22548 22554 22556 22558 Arthrotomy, temporomandibular joint Arthroplasty, temporomandibular joint, with or without autograft (includes obtaining graft) Arthroplasty, temporomandibular joint, with allograft Arthroplasty, temporomandibular joint, with prosthetic joint replacement Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; cervical Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; thoracic Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; lumbar Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; each additional vertebral segment (list separately in addition to primary procedure) Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; cervical Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; thoracic Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; lumbar Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; each additional vertebral segment (list separately in addition to code for primary procedure) Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); lumbar Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic or lumbar, each additional vertebral segment (list separately in addition to code for primary procedure) Arthrodesis, anterior transoral or extraoral technique, clivus-c1-c2 (atlas-axis), with or without excision of odontoid process Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); cervical below c2 Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); lumbar The Degge Group, Ltd. aTNF Switching Study 34 03/08/2016 CPT- 4 22585 22590 22595 22600 22610 22612 22614 22630 22632 22800 22802 22804 22857 22862 22865 23450 23455 26500 27280 27282 29800 29804 0090T 0092T 0093T 0095T 0096T 0098T 0163T Category description Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); each additional interspace (list separately in addition to code for primary procedure) Arthrodesis, posterior technique, craniocervical (occiput-c2) Arthrodesis, posterior technique, atlas-axis (c1-c2) Arthrodesis, posterior or posterolateral technique, single level; cervical below c2 segment Arthrodesis, posterior or posterolateral technique, single level; thoracic (with or without lateral transverse technique) Arthrodesis, posterior or posterolateral technique, single level; lumbar (with or without lateral transverse technique) Arthrodesis, posterior or posterolateral technique, single level; each additional vertebral segment (list separately in addition to code for primary procedure) Arthrodesis, posterior interbody technique, including laminectomy and/or discectomy to prepare interspace (other than for decompression), single interspace; lumbar Arthrodesis, posterior interbody technique, including laminectomy and/or discectomy to prepare interspace (other than for decompression), single interspace; each additional interspace (list separately in addition to code for primary procedure) Arthrodesis, posterior, for spinal deformity, with or without cast; up to 6 vertebral segments Arthrodesis, posterior, for spinal deformity, with or without cast; 7 to 12 vertebral segments Arthrodesis, posterior, for spinal deformity, with or without cast; 13 or more vertebral segments Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression), lumbar, single interspace Revision including replacement of total disc arthroplasty (artificial disc) anterior approach, lumbar, single interspace Removal of total disc arthroplasty (artificial disc), anterior approach, lumbar, single interspace Capsulorrhaphy, anterior; putti-platt procedure or magnuson type operation Capsulorrhaphy, anterior; with labral repair (eg, bankart procedure) Reconstruction of tendon pulley, each tendon; with local tissues (separate procedure) Arthrodesis, sacroiliac joint (including obtaining graft) Arthrodesis, symphysis pubis (including obtaining graft) Arthroscopy, temporomandibular joint, diagnostic, with or without synovial biopsy (separate procedure) Arthroscopy, temporomandibular joint, surgical Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression) cervical; single interspace Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression) cervical; each additional interspace (list separately in addition to code for primary procedure) Removal of total disc arthroplasty, anterior approach cervical; single interspace Removal of total disc arthroplasty, anterior approach cervical; each additional interspace (list separately in addition to code for primary procedure) Revision of total disc arthroplasty, anterior approach cervical; single interspace Revision of total disc arthroplasty, anterior approach cervical; each additional interspace (list separately in addition to code for primary procedure) Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression), lumbar, each The Degge Group, Ltd. aTNF Switching Study 35 03/08/2016 CPT- 4 Category description additional interspace 0164T 0165T Removal of total disc arthroplasty, anterior approach, lumbar, each additional interspace Revision of total disc arthroplasty, anterior approach, lumbar, each additional interspace ICD-9 Category description Incision and excision of joint structures Arthrotomy for removal of prosthesis (Includes removal of posterior spinal motion preservation (dynamic stabilization, facet replacement, interspinous 80.0* process) device(s)) 80.1* Other arthrotomy 80.2* Arthroscopy 80.3* Biopsy of joint structure 80.4* Division of joint capsule, ligament, or cartilage 80.5* Excision, destruction and other repair of intervertebral disc 80.6* Excision of semilunar cartilage of knee 80.7* Synovectomy 80.8* Other local excision or destruction of lesion of joint 80.9* Other excision of joint Repair and plastic operations on joint structures 81.1 Arthrodesis and arthroereisis of foot and ankle (Includes: arthrodesis of foot and ankle with: bone graft, external fixation device) 81.11 Ankle fusion, Tibiotalar fusion 81.12 Triple arthrodesis,Talus to calcaneus and calcaneus to cuboid and navicular 81.13 Subtalar fusion 81.14 Midtarsal fusion 81.15 Tarsometatarsal fusion 81.16 Metatarsophalangeal fusion 81.17 Other fusion of foot 81.18 Subtalar joint arthroereisis 81.2 Arthrodesis of other joint (Includes: arthrodesis with: bone graft external fixation device excision of bone ends and compression) 81.20 Arthrodesis of unspecified joint 81.21 Arthrodesis of hip 81.22 Arthrodesis of knee 81.23 Arthrodesis of shoulder 81.24 Arthrodesis of elbow 81.25 Carporadial fusion The Degge Group, Ltd. aTNF Switching Study 36 03/08/2016 ICD-9 Category description 81.26 81.27 81.28 81.29 81.3 81.30 Metacarpocarpal fusion Metacarpophalangeal fusion Interphalangeal fusion Arthrodesis of other specified joints Refusion of spine (Includes: arthrodesis of spine with: bone graft internal fixation correction of pseudarthrosis of spine) Refusion of spine, not otherwise specified Refusion of atlas-axis spine, Craniocervical fusion by anterior, transoral, or posterior technique, C1-C2 fusion by anterior, transoral, or posterior technique, Occiput C2 fusion by anterior, transoral, or posterior technique Refusion of other cervical spine, anterior technique (Arthrodesis of C2 level or below) Refusion of other cervical spine, posterior technique (Arthrodesis of C2 level or below) Refusion of dorsal and dorsolumbar spine, anterior technique (Arthrodesis of thoracic or thoracolumbar region) Refusion of dorsal and dorsolumbar spine, posterior technique (Arthrodesis of thoracic or thoracolumbar region) Refusion of lumbar and lumbosacral spine, anterior technique (Anterior lumbar interbody fusion (ALIF); Arthrodesis of lumbar or lumbosacral region) Refusion of lumbar and lumbosacral spine, lateral transverse process technique Refusion of lumbar and lumbosacral spine, posterior technique, Arthrodesis of lumbar or lumbosacral region 81.31 81.32 81.33 81.34 81.35 81.36 81.37 81.38 81.39 81.4 81.40 81.42 81.43 81.44 81.45 81.46 81.47 81.49 81.5 81.51 81.52 81.53 81.54 81.55 Refusion of spine, not elsewhere classified Other repair of joint of lower extremity (Includes: arthroplasty of lower extremity with: external traction or fixation, graft of bone (chips) or cartilage internal fixation device) Repair of hip, not elsewhere classified Five-in-one repair of knee, Medial meniscectomy, medial collateral ligament repair, vastus medialis advancement, semitendinosus advancement, and pes anserinus transfer Triad knee repair, Medial meniscectomy with repair of the anterior cruciate ligament and the medial collateral ligament (O'Donoghue procedure) Patellar stabilization (Roux-Goldthwait operation for recurrent dislocation of patella) Other repair of the cruciate ligaments Other repair of the collateral ligaments Other repair of knee Other repair of ankle Joint replacement of lower extremity (Includes: arthroplasty of lower extremity with: external traction or fixation graft of bone (chips) or cartilage internal fixation device or prosthesis) Total hip replacement, Replacement of both femoral head and acetabulum by prosthesis, Total reconstruction of hip Partial hip replacement, Bipolar endoprosthesis Revision of hip replacement, not otherwise specified, Revision of hip replacement, not specified as to components(s) replaced, (acetabular, femoral, both) Total knee replacement (Bicompartmental, Tricompartmental, Unicompartmental (hemijoint)) Revision of knee replacement,not otherwise specified The Degge Group, Ltd. aTNF Switching Study 37 03/08/2016 ICD-9 Category description 81.56 81.57 81.59 81.6 81.62 81.63 81.64 81.65 Total ankle replacement Replacement of joint of foot and toe Revision of joint replacement of lower extremity, not elsewhere classified Other procedures on spine Fusion or refusion of 2-3 vertebrae Fusion or refusion of 4- 8 vertebrae Fusion or refusion of 9 or more vertebrae Percutaneous vertebroplasty, Injection of bone void filler (cement) (polymethylmethacrylate) (PMMA) into the diseased or fractured, vertebral body Percutaneous vertebral augmentation, Insertion of inflatable balloon, bone tamp, or other device displacing (removing) (compacting) bone to create a space (cavity) (void) prior to the injection of bone void filler (cement) (polymethylmethacrylate) (PMMA) or other substance, Arcuplasty, Kyphoplasty, SKyphoplasty, Spineoplasty Arthroplasty and repair of hand, fingers and wrist (Includes: arthroplasty of hand and finger with: external traction or fixation, graft of bone (chips) or cartilage, internal fixation device or prosthesis) Arthroplasty of metacarpophalangeal and interphalangeal joint with implant Arthroplasty of metacarpophalangeal and interphalangeal joint without implant Total wrist replacement Arthroplasty of carpocarpal or carpometacarpal joint with implant Arthroplasty of carpocarpal or carpometacarpal joint without implant Other repair of hand, fingers and wrist Arthroplasty and repair of shoulder and elbow (Includes: arthroplasty of upper limb NEC with: external traction or fixation graft of bone (chips) or cartilage internal fixation device or prosthesis Total shoulder replacement Partial shoulder replacement Repair of recurrent dislocation of shoulder Other repair of shoulder, Revision of arthroplasty of shoulder Total elbow replacement Other repair of elbow Other operations on joint structures Arthrocentesis, Joint aspiration Injection of therapeutic substance into joint or ligament Suture of capsule or ligament of upper extremity Suture of capsule or ligament of ankle and foot Suture of capsule or ligament of ankle and foot Suture of capsule or ligament of other lower extremity 81.66 81.7 81.71 81.72 81.73 81.74 81.75 81.79 81.8 81.80 81.81 81.82 81.83 81.84 81.85 81.9 81.91 81.92 81.93 81.94 81.94 81.95 The Degge Group, Ltd. aTNF Switching Study 38 03/08/2016 ICD-9 Category description 81.96 81.97 81.98 81.99 Other repair of joint Revision of joint replacement of upper extremity (Partial, Removal of cement spacer, Total) Other diagnostic procedures on joint structures Other * The following fourth-digit subclassification is for use with ICD-9-CM procedure code range 80.0-80.9: 0 unspecified site 1 shoulder 2 elbow 3 wrist 4 hand and finger 5 hip 6 knee 7 ankle 8 foot and toe 9 other specified sites The Degge Group, Ltd. aTNF Switching Study 39 03/08/2016 APPENDIX G. Medications Used to Define DMARD Treatment* Generic Brand Names Auranofin Ridaura Aurothioglucose Solganal Azathioprine Azathioprine Usp Tablets Azathioprine Sodium Imuran Cyclosporine Sangcya Solution Oral; Gengraf Capsules Gold Chloride Gold Chloride Trihydrate Gold Sodium Thiomalate Myochrysine Hydroxychloroquine Hydroxychloroquine Sulfate; Plaquenil Leflunomide Arava Tablets Methotrexate† Rheumatrex Dose Pack†; Folex† Minocycline Minocycline Hydrochloride; Minocin Penicillamine Cuprimine Capsules Sulfasalazine Sulfasalazine *NDC codes are not displayed due to the excessive number † Methotrexate products were treated as a separate covariate APPENDIX H. J-Codes Used to Define DMARD Treatment J Code Code description J2910 Aurothioglucose J7501 Azathioprine parenteral 100 mg J7500 Azathioprine oral 50 mg J7516 Cyclosporine parenteral 250 mg J7502 Cyclosporine oral 100 mg J7515 Cyclosporine oral 25 mg J1600 Inj gold sodium thiomalate to 50 mg J8610 Methotrexate oral 2.5 mg† J9250 Methotrexate sodium 5 mg† J9260 Methotrexate sodium 50 mg† † Methotrexate products were treated as a separate covariate The Degge Group, Ltd. aTNF Switching Study 40 03/08/2016 APPENDIX I. Medications Used to Define Oral Corticosteroids* Generic Dexamethasone Methylprednisolone Prednisolone Prednisone *NDC codes are not displayed due to the excessive number The Degge Group, Ltd. aTNF Switching Study 41 03/08/2016 APPENDIX J. Antidiabetic Drugs Used to Define History of Diabetes* Generic Acarbose Acetohexamide Chlorpropamide Exenatide Glimepiride Glipizide Glucagon Glyburide Insulin Insulin Aspart Insulin Beef/Pork Insulin Bovine Insulin Detemir Insulin Glargine Recombinant Insulin Glulisine Recombinant Insulin Human Insulin I-131 Insulin Inhalation, Rapid Acting Insulin Lispro Recombinant Metformin Metformin-Rosiglitazone Miglitol Nateglinide Pioglitazone Pramlintide Acetate Repaglinide Rosiglitazone Maleate Sitagliptin Phosphate Tolazamide Tolbutamide Troglitazone *NDC codes are not displayed due to the excessive number The Degge Group, Ltd. aTNF Switching Study 42 03/08/2016 APPENDIX K. Medications Used to Define Asthma/COPD Treatment* Generic Albuterol Albuterol Sulfate/Ipratropium Bromide Aminophylline Arformoterol Tartrate Beclomethasone Beclomethasone Dipropionate Budesonide Cromolyn Dextrose Dyphylline Flunisolide Fluticasone Propionate/Salmeterol Xinafoate Formoterol Formoterol Fumarate Ipratropium Bromide Isoproterenol Hydrochloride Levalbuterol Levalbuterol Tartrate Metaproterenol Mometasone Mometasone Furoate Montelukast Omalizumab Pirbuterol Salmeterol Salmeterol Xinafoate Terbutaline Theophylline Theophylline Calcium Salicylate Theophylline Sodium Glycinate Triamcinolone Triamcinolone Acetonide Zafirlukast Zileuton *NDC codes are not displayed due to the excessive number The Degge Group, Ltd. aTNF Switching Study 43 03/08/2016