Issues in Biotechnology Study Guide for Quiz on Forensics Forensics: Trace Evidence DNA-based Forensics: The Real Story The National Forensic Debate: Public Safety vs. The Right of Privacy BCH 190 1. Who recognizes, identifies, individualizes and evaluates physical evidence using the methods of natural sciences in matters of legal significance? (A) Detectives (B) Criminologists (C) Criminalists (D) Criminals (E) Local police 2. The CT CODIS Database collects two types of samples; (1) Convicted Offender Samples that include all Felony Convictions (since 03/01/04) and, (2) Forensic Unknowns that include any DNA profile from an evidentiary sample that does not match the victim or an elimination known. There are currently 10,793 offenders in CT Database and over 1500 offender samples are added per month. Currently there are how many felons on the CT database? (A) 1 out of 50 males in CT (B) 1 out of 1000 males in CT (C) 1 out of 10,000 males in CT (D) None of these answers is correct 3. CODIS stands for: (A) Combined DNA Index System (B) Combinatorial Operations for DNA Identification Systems (C) Criminalists for DNA Indexing Systems (D) None of these answers are correct 4. PCR is used in plant genetics, animal cloning, drug discovery, cancer research and forensics. (A) False (B) True (C) only when a plant geneticist thinks his collaborator stole his work (D) only when forensic analysis involves plant material from a crime scene 5. DNA analysis is now a common and widely accepted forensic tool used to analyze evidentiary DNA. A. True B. False C. Only in less than half the states D. Only used on convicted felons 6. In the national debate about the use of forensic DNA analysis and the building of DNA databases (such as an all felon database vs. an all arrestee database of a general public database) there are two competing views. One view holds that DNA testing and the building of databases is a matter of public safety: DNA solves crimes; only criminals should fear DNA testing or databases. The opposing view holds that (A) There are privacy concerns, maintaining that DNA information is different where there is significant potential for abuse. (B) Misused DNA evidence has obviously exonerated guilty people citing the OJ Simpson trial. No one is looking for the criminal of that crime. (C) That the PCR approach to DNA testing is not accurate or reliable (D) DNA databases will be far too costly to maintain or use. 7. Considering the National debate on DNA forensic databases which of the following is not an issue? (A) Constitutionality of taking DNA samples from arrestees and suspects. (B) Practical/financial considerations of Expanding DNA Databanks. (C) What happens to the sample after profiling? (D) Post-conviction DNA testing. >150 Exonerated-August 2004 (E) Accuracy of the DNA testing protocols 8. (STR) technology is used to evaluate specific regions (loci) within nuclear DNA. Variability in STR regions can be used to distinguish one DNA profile from another. The Federal Bureau of Investigation (FBI) uses a standard set of 13 specific STR regions for CODIS. CODIS is a software program that operates local, state, and national databases of DNA profiles from convicted offenders, unsolved crime scene evidence, and missing persons. The odds that two individuals will have the same 13-loci DNA profile is extremely unlikely. STR stands for: (A) Standard Temperature Reactions (B) Statewide Tracking Reliabilities (C) Short Tandem Repeats (D) Starwars Tracking Reactions 9. There was a homicide in 1994. A plastic bag was found in the shallow grave of the victim with a bloody jacket and some trace hairs were recovered. What techniques would be best used to match the hairs to the suspect’s cat, snowball? (A) PCR providing a perfect match with cat STRs (B) all of these techniques together provide the best case (C) PCR of the blood from the jacket to tie the DNA of the suspect to the jacket (D) scanning electron microscopy of the trace evidence showed that they were those of a cat 10. Research on how the principles of biology and evolution are involved with criminal behavior is in its infancy. The principal mechanism of evolution, which includes two processes that operate together: chance variability and selection, is called: (A) Natural Selection (B) Ingenuity (C) Conjugation (D) Predation (E) Intelligent design 11. DNA databases are controversial because (A) Because of the conflict between public safety and civil liberties (B) They have not proven useful to solving crimes (C) They use crime genes to evaluate unsuspected criminals from the pubic (D) They have been too expensive or computationally too difficult to manage on a large scale 12. There was a double murder in Seattle in 1996 and preliminary investigation came up with two suspects. A couple had been torture and shot dead along with their pet dog. There was blood on one of the suspect’s clothing. The blood on the clothing could be best matched with that of the dog by doing what? (A) looking for matching dogs hairs at the crime scene (B) finding no dog blood on the second suspect (C) using PCR on both samples with known molecular makers for dogs (D) obtaining the records from the local veterinarian 13. What are the odds of two people’s DNA matching one another given the nationally used 13 CODIS core of STR loci used by state and federal forensics experts? (A) Over 1 in a billion (B) 1 in 3 million (C) 1 in 700,000 (D) 1 in 7,000 E) less than 1 in 90 14. Which of these items could be a source for possible DNA forensic testing: (A) All of these items can be used for DNA testing (B) cigarette butts (C) general clothing: including gloves, bandanas, ski masks, baseball caps (D) condoms (inside vs. outside) (E) a bloody knife 15. How does forensic testing help in a criminal investigation? (A) by linking a suspect to a victim (B) by linking a victim to crime scene (C) by linking a suspect to crime scene (D) by any or all of the answers 16. Evolution: (A) has been demonstrated at the molecular level in many organisms (B) of a new species has not occurred in the last 100 years (C) has been disproven by the believers of Intelligent Design (D) despite that if all of the factual science in support of it were printed and stacked that the documents would possibly fill a building the size of a Walmart, there is no hard evidence that it even occurs (E) has demonstrated to be thermodynamically impossible 17. Darwin conceived that new species developed as populations with different forms and functions diverged and that evolution occurs: (A) through natural selection in a population that includes variation (B) through and inheritance of acquired traits that an organism willed into being for its own purpose (C) only in the animal kingdom (D) only until the year 1A.D. at which point all organisms became genetically 18. The numbers of repeat offenses is one reason people support felon DNA databases. Collecting samples from offenders convicted of all felonies could help insure their DNA profiles are in the Database before the commit their first violent act. There is a 67% recidivism rate among convicted sex offenders and the average number of sexual assaults per offender is 8-13. As it turns out felons are often opportunistic and commit more than one type of crime. 52% of the offenders linked to sexual assaults and homicides by DNA Database matches had a prior conviction of what type of crime? (A) Burglary (B) Assault & Battery (C) Kidnapping (D) Sex offenses against children (E) White collar crimes 19. Why would analyzing the DNA of burglars reduce the violent crime rate, theoretically? (A) DNA testing would prove that criminals are genetically predisposed to crime (B) 50% of non-violent criminals go on to commit violent crimes, analysis would make proving guilt and making arrests easier (C) It wouldn’t (D) No answer listed is correct 20. Why should we expand forensic DNA databases? (A) More hits. Approximately half all violent criminals have non-violent prior convictions. If only collect violent offenders, likelihood of hit (rape/homicide case) is reduced by ~ 85%. (B) Exclude more people who could not be the source of the DNA profile (C)) Protect public safety (D) all of these reasons 21. The world’s highest rape rate of all countries that publish such data is: (A) Japan (B) Canada (C) The United States (D) England (E) Italy 22. An American woman is _____ times more likely to be raped than to die in a car crash (A) two (B) five (C) ten (D) the same 23. X % of rape victims are females under the age of 18 (A) 12% (B) 28% (C) 37% (D) 61% 24. One out of every _____ women currently in college has been raped. (A) 5 (B) 7 (C) 17 (D) 170 25. Approximately 28% of rape victims are raped by their husbands, and X % by an acquaintance, (A) 5 (B) 25 (C) 35 (D) 55 26. X % of sexual assaults are perpetrated by assailants well known to the victim (A) 21 (B) 31 (C) 51 (D) 71 27. X % of sexual assaults are perpetrated by assailants well known to the victim (A) 21 (B) 31 (C) 51 (D) 71 Take back the Night