Name _______________________________ Date __________________ Ch 11 Mendel and Gene Idea Overview – just read this section Concept 11.1 Mendel used the scientific approach to identify two laws of inheritance 1. Explain the difference between a character and a trait. 2. What is hybridization? 3. Explain the following: P generation - F1 generation - F2 generation – 4. Explain the law of segregation. 5. Review the following terms: Punnett square, homozygous, heterozygous, phenotype and genotype. 6. Explain what happens in a test cross. Why is it done? 7. Explain the law of independent assortment. 8. Review the terms monohybrid cross and dihybrid cross and complete the following. Monohybrid cross PP x pp where P = purple, p = white Genotypes ___________________________________________ Phenotypes __________________________________________ Pp x Pp Genotypes _____________________________________________ Phenotypes _____________________________________________ Dihybrid cross YYRR x yyrr where Y = yellow, y = green, R = round, r = wrinkled Genotypes ________________________________________________________________ Phenotypes ________________________________________________________________ YyRr x YyRr Genotypes _________________________________________________________________ Phenotypes _________________________________________________________________ Concpet 11.2 The laws of probability govern Mendelian inheritance 9. Explain the multiplication rule and give an example 10. Explain the addition rule and give an example. 11. Complete #2 of the Concept check 11.2 on p. 214. 12. Complete the “What if” question from the Concept check 11.2 on p. 214. Concept 11.3 Inheritance patterns are often more complex than predicted by simple Mendelian genetics 13. Explain the following terms and give examples of each. a. complete dominance b. incomplete dominance c. codominance 14. To look at the relationship between dominance and phenotype, explain Tay-Sachs disease. 15. Not all dominant alleles for a particular character are found predominantly in a population. Give an example from the book where a recessive allele is the predominant trait. 16. What is meant by multiple alleles? 17. Explain pleiotropy. 18. Explain epistasis and give an example. 19. Explain polygenic inheritance and give an example. 20. Give an example of how the environment can affect an inherited trait. Concept 11.4 Many human traits follow Mendelian patterns of inheritance. 21. What is a pedigree? 22. Draw the symbols that represent people and conditions in a pedigree a. male b. female c. affected male d. affected female e. carrier 23. Explain the following diseases – What effect they have on the body and what causes them. Disease Cystic fibrosis Effect on body Sickle –cell anemia Achondroplasia Huntington’s Disease 24. What are multifactorial disorders? Give an example. 25. What do genetic counselors do? Cause