PUBLICATIONS
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Schmidt RE, Matchinsky FM, Godfrey DA, Williams AD, and McDougal DB Jr: Fast and
slow axoplasmic flow in sciatic nerve of diabetic rats. Diabetes 1975; 24:1081-1085
Schmidt RE, McDougal DB Jr: Axonal transport of selected particle-specified enzymes in
rat sciatic nerve in vivo and its response to injury. J Neurochem 1978; 30:527-535
Schmidt RE, Ross CD, McDougal DB Jr: Effect of sympathectomy on axoplasmic
transport of selected enzymes including MAO and other mitochondrial enzymes. J
Neurochem 1978; 30:537-541
Schmidt RE, Yu MJC, McDougal DB Jr: Turnaround of axoplasmic transport of selected
particle-specific enzymes at an injury in control and DFP-treated rats. J Neurochem
1980; 35:641-652
Schmidt RE, Johnson EM Jr, Nelson JS: Experimental diabetic autonomic neuropathy.
Am J Pathol 1981; 103:210-225
Schmidt RE, Geller DM, Johnson EM Jr: Characterization of increased plasma dopamineß-hydroxylase activity in rats with experimental diabetes. Diabetes 1981;30:416-423
Schmidt RE, Scharp DW: Axonal dystrophy in experimental diabetic autonomic
neuropathy. Diabetes 1982; 31:761-770
Gilbert WR, Garwood MM, Agrawal D, Schmidt RE, Agrawal HC: Immunoblot
identification of phosphorylated basic proteins of rat and rabbit CNS and PNS myelin:
Evidence for four phosphorylated basic proteins and P2 in rat PNS myelin:
Neurochemical Research 1982; 7:1495-1506
Schmidt RE, Plurad SB, Olack BJ, Scharp DW: The effect of pancreatic islet
transplantation and insulin therapy on experimental diabetic autonomic neuropathy.
Diabetes 1983; 32:532-540
Johnson EM Jr, Osborne PA, Rydel RE, Schmidt RE, Pearson, J: Characterization of the
effects of autoimmune nerve growth factor deprivation in the developing guinea pig.
Neuroscience 1983;8:631-642
Manning PT, Schmidt RE, Johnson EM Jr: Guanethidine-induced destruction of
peripheral sympathetic neurons occurs by an immune-mediated mechanism. J
Neuroscience 1983; 3:714-724
Agrawal HC, Schmidt RE, Agrawal D: In vivo incorporation of (H3) palmitic acid into
Po, the major intrinsic protein of rat sciatic nerve myelin: Evidence for covalent linkage
of fatty acid to Po. J Biol Chem 1983; 258:6556-6560
Schmidt RE, Plurad SB, Modert CW: Neuroaxonal dystrophy in the autonomic ganglia of
aged rats. J Neuropathol Exp Neurol 1983; 42:376-390
Schmidt RE, Modert CW, Yip HK, Johnson EM Jr: Retrograde axonal transport of
intravenously administered I125-Nerve growth factor in rats with streptozotocininduced diabetes. Diabetes 1983; 32:654-663
Schmidt RE, Plurad SB, Modert CW: Experimental diabetic autonomic neuropathy characterization in streptozotocin-diabetic Sprague-Dawley rats. Laboratory
Investigation 1983;49:538-552
Clark HB, Schmidt RE: Identification of dystrophic sympathetic axons in experimental
diabetic autonomic neuropathy. Brain Research 1984; 293:390-395
Robert E. Schmidt, M.D., Ph.D.
Page 2
17. Kreusser KL, Schmidt RE, Shackelford GDF, Volpe JJ: Value of ultrasound for
identification of acute hemorrhagic necrosis of thalamus and basal ganglia in an
asphyxiated term infant. Annals of Neurology 1984; 16:361-363
18. Schmidt RE, Modert CW: Orthograde, retrograde and turnaround axonal transport of
dopamine-ß-hydroxylase: response to axonal injury. J Neurochem 1984; 43:865-870
19. Rich KM, Yip HK, Osborne PA, Schmidt RE, Johnson EM Jr: Role of Nerve Growth
Factor in the adult dorsal root ganglia neuron and its response to injury. J Comp Neurol
1984; 230:110-118
20. Schmidt RE, Plurad SB: Ultrastructural appearance of intentionally frustrated axonal
regeneration in rat sciatic nerve. J Neuropathol Exp Neurol 1985; 44:130-146
21. Schmidt RE, Yip HK: Retrograde axonal transport in rat ileal mesenteric nerves. I.
Characterization using intravenously administered 125I-Nerve Growth Factor and effect
of chemical sympathectomy. Diabetes 1985: 34:1222-1229
22. Schmidt RE, Plurad SB, Saffitz JE, Grabau GG, Yip HK: Retrograde axonal transport of
125I-Nerve Growth Factor in rat ileal mesenteric nerves. II. Effect of streptozotocin
diabetes. Diabetes 1985; 34:1230-1240
23. Schmidt RE, Grabau GG, Yip HK: Retrograde axonal transport of 125I-Nerve Growth
Factor in ileal mesenteric nerves in vitro - Effect of streptozotocin diabetes. Brain
Research 1986; 378:325-336
24. Schmidt RE, Plurad SB: Ultrastructural and biochemical characterization of autonomic
neuropathy in rats with chronic streptozotocin diabetes. J Neuropathol Exp Neurol
1986; 45:525-544
25. Palmatier MA, Schmidt RE, Plurad SB, Johnson EM Jr: Sympathetic neuronal destruction
in Macaque monkeys by guanethidine and guanacline. Ann Neurol 1987; 21:46-52
26. Schmidt RE, Modert CW, Grabau GG: Orthograde and retrograde axonal transport of
dopamine-ß-hydroxylase in ileal mesenteric nerves of rats with chronic streptozotocin
diabetes. Brain Res 1987:401: 142-146
27. Schmidt RE, Plurad SB, Clark HB: Acrylamide induced sympathetic autonomic
neuropathy resulting in pineal denervation. Lab Invest 1987; 56:505-517
28. Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM Jr: Inhibitors
of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth
factor deprivation. J Cell Biol 1988; 106:829-844
29. Schmidt RE, Plurad DA, Roth KA: Effects of chronic experimental streptozotocininduced diabetes on the noradrenergic and peptidergic innervation of the rat alimentary
tract. Brain Res 1988; 458:353-360
30. Schmidt RE, McAtee SJ, Plurad DA, Parvin CA, Cogswell BE, Roth KA: Differential
susceptibility of prevertebral and paravertebral sympathetic ganglia to experimental injury.
Brain Res 1988; 460:214-226
31. Schmidt RE, Plurad SB, Sherman WR, Williamson JR, Tilton, RG: Effects of the aldose
reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and
sorbitol in sympathetic autonomic ganglia of streptozocin-diabetic rats. Diabetes 1989;
38:569-579
32. Schmidt RE, Plurad DA, Plurad SB, Cogswell BE, Diani AR, Roth KA: Ultrastructural
and immunohistochemical characterization of autonomic neuropathy in genetically
diabetic Chinese hamsters: Lab Investigation 1989; 61:77-92
33. Schmidt RE, Cogswell BE: Tyrosine hydroxylase activity in the sympathetic nervous
system of rats with streptozocin-induced diabetes: Diabetes 1989; 38:959-968
Robert E. Schmidt, M.D., Ph.D.
Page 3
34. Schmidt RE, Plurad SB, Olack BJ, Scharp DW: The effect of pancreatic islet
transplantation and insulin therapy on neuroaxonal dystrophy in sympathetic autonomic
ganglia of streptozocin-diabetic rats: Brain Research 1989; 497:393-398
35. Schmidt RE, Summerfield AL, Hickey WF: Ultrastructural and immunohistologic
characterization of guanethidine-induced destruction of peripheral sympathetic neurons:
J Neuropathol Exp Neurol 1990; 49:150-167
36. Schmidt RE, Chae HY, Parvin CA, Roth KA: Neuroaxonal dystrophy in aging human
sympathetic ganglia. Am J Pathol 1990; 136:1327-1338
37. Ruit KG, Osborne PA, Schmidt RE, Johnson EM Jr, Snider WD: Nerve growth factor
regulates sympathetic ganglion cell morphology and survival in the adult mouse. J
Neurosci 1990; 10:2412-2419
38. Schmidt RE, Coleman BD, Nelson JS: Differential effect of chronic vitamin E deficiency
on the development of neuroaxonal dystrophy in gracile/cuneate nuclei and prevertebral
sympathetic ganglia. Neurosci Lett 1991; 123:102-106
39. Schmidt RE, Plurad SB, Coleman BD, Williamson JR, Tilton RG: Effects of sorbinil,
dietary myo-inositol supplementation, and insulin on resolution of neuroaxonal
dystrophy in mesenteric nerves of streptozocin-diabetic rats. Diabetes 1991; 40:574582
40. Schmidt RE, Spencer SA, Coleman BD, Roth KA: Immunohistochemical localization of
GAP-43 in rat and human sympathetic nervous system - Effects of aging and diabetes.
Brain Research 1991;552:190-197
41. Schmidt RE, Dorsey DA, Roth KA: Immunohistochemical characterization of NPY and
substance P containing nerve terminals in aged and diabetic human sympathetic
ganglia. Brain Research 1992; 583:320-326
42. Schroer JA, Plurad SB, Schmidt RE: Fine structure of presynaptic axonal terminals in
sympathetic autonomic ganglia of aging and diabetic human subjects. Synapse 1992;
12:1-13
43. Hickey WF, Ueno K, Hiserodt JC, Schmidt RE: Exogenously induced NK cell mediated
neuronal killing: a novel pathogenetic mechanism. J Exp Med 1992;176:811-817
44. Schmidt RE, Plurad SB, Parvin CA, Roth KA: The effect of diabetes and aging on human
sympathetic autonomic ganglia. Am J Pathol 1993;143:143-153.
45. Schmidt RE, Dorsey DA, McDaniel ML, Corbett JA: Characterization of NADPH
diaphorase activity in rat sympathetic autonomic ganglia -- Effect of diabetes and aging.
Brain Research 1993;617:343-348
46. Vass K, Hickey WF, Schmidt RE, Lassmann, H: Bone marrow derived elements in the
peripheral nervous system: An immunohistochemical and ultrastructural investigation
in chimeric rats. Lab Investigation 1993;69:275-282
47. Dorsey DA, Schmidt RE: Correlation of GAP-43 immunoreactivity with subpopulations
of chromaffin cells in rat adrenal medulla. Neurosci. Lett., 1993;162:29-33
48. Zhang LI, Schmidt RE, Yan Q, Snider WD: NGF and NT-3 have differing effects on the
growth of dorsal root axons in developing mammalian spinal cord. J. Neurosci
1994;14:5187-5201
49. Ohara S, Roth KA, Beaudet LN, Schmidt RE: Transganglionic NPY response to sciatic
nerve injury in young and aged rats. J. Neuropathol Exp Neurol 1994;53:646-662
50. Schmidt RE, Beaudet LN, Plurad SB, Snider WD, Ruit KG: Pathologic alterations in preand post-synaptic elements in aged mouse sympathetic ganglia. J. Neurocytol,
1995;24:189-206.
Robert E. Schmidt, M.D., Ph.D.
Page 4
51. Schroer JA, Beaudet LN, Schmidt RE: Autoimmune nerve growth factor deprivation in
rats does not result in sympathetic neuroaxonal dystrophy. Synapse 1995;20:249-256.
52. Stewart GR, Olney JW, Schmidt RE, Wozniak DF: Mineralization of the globus pallidus
following excitotoxic lesions of the basal forebrain. Brain Research 1995; 695:81-87.
53. Tornusciolo DRZ, Schmidt RE, Roth KA: Simultaneous detection of TDT-mediated
dUPT-biotin nick end labeling (TUNEL)-positive cells and multiple
immunohistochemical markers in single tissue sections. Biotechniques, 1995; 19:800805.
54. Ohara S, Tantuwaya V, DiStefano PS, Schmidt RE: Exogenous NT-3 mitigates the
transganglionic neuropeptide response to sciatic nerve injury. Brain Research, 1995;
699:143-148..
55. Ohara S, Beaudet LN, Schmidt RE: Transganglionic response of GAP-43 in the gracile
nucleus to sciatic nerve injury in young and aged rats. Brain Research, 1995; 705:325331.
56. Schmidt RE, Dorsey DA, Beaudet LN, Reiser KM, Williamson JR and Tilton RG: Effect
of aminoguanidine on the frequency of neuroaxonal dystrophy in the superior
mesenteric sympathetic autonomic ganglia of rats with streptozocin-induced diabetes.
Diabetes 1996; 45:284-290.
57. Tantuwaya VS, Bailey SB, Schmidt RE, Villadiego A, Tong JXX, Rich KM: Peripheral
nerve regeneration through silicone chambers in streptozocin-induced diabetic rats,
Brain Research, 1997; 759:58-66.
58. Schmidt RE, Dorsey DA, Parvin CA, Beaudet LN, Plurad SB, Roth KA: Dystrophic
axonal swellings develop as a function of age and diabetes in human dorsal root
ganglia, J. Neuropathol. Exp. Neurol, 1997; 56:1028-1043.
59. Schmidt RE, Beaudet LN, Plurad SB, Dorsey DA: Axonal cytoskeletal pathology in aged
and diabetic human sympathetic autonomic ganglia, Brain Research, 1997; 769:375383.
60. Gökden M, Roth KA, Carroll SL, Wick MR, Schmidt RE: Clear cell neoplasms and
pseudoneoplastic lesions of the central nervous system, Seminars in Diagnostic Path.,
1997; 14:253-269.
61. Langer JC, Birnbaum EE, Schmidt RE: Histology and function of the internal anal
sphincter after injection of botulinum toxin, J. Surgical Res., 1997; 73:113-116.
62. Schmidt RE, Dorsey DA, Selznick LA, DiStefano PS, Carroll SL, Beaudet LN, Roth KA:
Neurotrophin sensitivity of prevertebral and paravertebral rat sympathetic ganglia, J.
Neuropathol. Exp. Neurol., 1998; 57:158-167.
63. Schmidt RE, Dorsey DA, Beaudet LN, Plurad SB, Parvin CA, Bruch LA: Vacuolar
neuritic dystrophy in aged mouse superior cervical sympathetic ganglia is strainspecific, Brain Res., 1998; 806:141-151.
64. Cross AH, Manning PT, Keeling RM, Schmidt RE, Misko TP: Peroxynitrite formation
within the central nervous system in active multiple sclerosis, J. Neuroimmunol., 1998;
88:45-56.
65. Lee BCP, Schmidt RE, Hatfield GA, Bourgeois B, Park TS: MRI of focal cortical
dysplasia, Neuroradiology, 1998; 40:675-683.
66. Santorolli FM, Tanji K, Shanske S, Krishna S, Schmidt RE, Greenwood RS, Dimauro S,
DeVivo DC: The mitochondrial DNA A8344G mutation in Leigh syndrome revealed
by analysis in paraffin-embedded sections: Revisiting the past. Ann. Neurol., 1998;
44:962-964.
Robert E. Schmidt, M.D., Ph.D.
Page 5
67. Schmidt RE, Dorsey DA, Beaudet LN, Plurad SB, Williamson JR, Ido Y: Effect of
sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy. J.
Neuropathol. Exp. Neurol., 1998; 57(12):1175-1189.
68. Schmidt RE, Dorsey DA, Beaudet LN, Plurad SB, Parvin CA, Miller MA: Insulin-like
growth factor I reverses experimental diabetic autonomic neuropathy. Am. J. Pathol.,
1999; 155:1651-1660.
69. Schmidt RE, Dorsey DA, Roth KA, Parvin CA, Hounsom L, Tomlinson DR: Effect of
streptozotocin-induced diabetes on NGF, p75NTR and Trk A content of prevertebral
and paravertebral rat sympathetic ganglia. Brain Res., 2000; 867:149-156.
70. Cai DX, Mafra M, Schmidt RE, Scheithauer BW, Part TS, Perry A: Medulloblastomas
with extensive posttherapy neuronal maturation. J. Neurosurg. 2000; 93:330-334.
71. Schmidt RE, Dorsey DA, Beaudet LN, Plurad SB, Parvin CA, Ohara S: Effect of IGF-I
and neurotrophin-3 on gracile neuroaxonal dystrophy in diabetic and aging rats, Brain
Res. 2000; 876:88-94.
72. Schmidt RE, Dorsey DA, Beaudet LN, Parvin CA, Escandon E: Effect of NGF and
neurotophin-3 treatment on experimental diabetic autonomic neuropathy. J.
Neuropathol. Exp. Neurol. 2001; 60:263-273.
73. Chiesa R, Pestronk A, Schmidt RE, Tourtelotte W, Ghetti B, Piccardo P, Harris DA:
Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of
transgenic mice expressing a prion protein insertional mutation. Neurobiol. Dis. 2001;
8:279-288.
74. Powers JM, Rosenblatt DS, Schmidt RE, Cross AH, Black JT, Moser AB, Moser HM,
Morgan DJ: Neurological and neuropathologic heterogeneity in two brothers with
cobalamin C deficiency (cblC). Ann. Neurol. 2001; 49:396-400.
75. Shao J-S, Engle M, Xie Q, Schmidt RE, Narisawa S, Millan JL, Alpers DH: Effect of
tissue non-specific alkaline phosphatase in maintenance of structure of murine colon
and stomach. Micr. Res. Tech. 2000; 51:121-128.
76. Josephson SA, Schmidt RE, Millsap P, McManus DQ, Morris JC: Autosomal dominant
Kuf’s disease: A cause of early-onset dementia. J. Neurol. Sci. 2001; 188:51-60.
77. Zaidi AU, McDonough JS, Klocke BJ, Latham CB, Korsmeyer SJ, Flavell RA, Schmidt
RE, Roth KA. Chloroquine-induced neuronal cell death is p53 and Bcl-2 familydependent but caspase-independent, J. Neuropathol. Exp. Neurol. 2001; 60:937-945.
78. Schmidt RE, Dorsey DA, Beaudet LN, Plurad SB, Parvin CA, Yarasheski KE, Smith SR,
Lang H-L, Williamson JR, Ido Y. Inhibition of sorbitol dehydrogenase exacerbates
autonomic neuropathy in rats with streptozotocin-induced diabetes, J. Neuropathol.
Exp. Neurol. 2001; 60:1153-1169.
79. Schmidt RE. Neuronal preservation in the sympathetic ganglia of rats with chronic
streptozotocin-induced diabetes, Brain Research 2001; 921:256-259.
80. Lin S-P, Schmidt RE, McKinstry RC, Ackerman JJH, Neil J: Investigations of
mechanisms underlying the MR fogging effect. J. Mag. Res. Imag. 2002; 15:130-136.
81. Huijbregts RPH, Roth KA, Schmidt RE, Carroll SL. Hypertrophic neuropathies and
malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial
growth factor –3 in myelinating Schwann cells. J. Neurosci 2003; 23:7269-7280.
82. Chang LK, Schmidt RE, Johnson, EM Jr. Caspase inhibition uncovers bioenergetic and
ultrastructural changes in NGF-deprived sympathetic neurons and their roles in caspaseindependent death. J. Cell Biol. 2003;162:245-256.
Robert E. Schmidt, M.D., Ph.D.
Page 6
83. Schmidt RE, Dorsey DA, Beaudet LN, Peterson RG. Analysis of the Zucker Diabetic
Fatty (ZDF) type 2 diabetic rat model suggests a neurotrophic role for insulin/IGF in
diabetic autonomic neuropathy, Am J Pathol 2003; 163:21-28.
84. Schmidt RE, Dorsey DA, Beaudet LN, Frederick KE, Parvin CA, Plurad SB and Levisetti
MG. Non-Obese Diabetic (NOD) mice rapidly develop dramatic sympathetic neuritic
dystrophy -- A new experimental model of diabetic autonomic neuropathy, Am. J.
Pathol. 2003, 163: 2077-2091.
85. Fuller CE, Schmidt RE, Roth KA, Burger PC, Scheithauer BW, Banerjee R, Trinkaus K,
Lytle R, Perry A. Clinical utility of fluorescence in situ hybridization (FISH) in
morphologically ambiguous gliomas with hybrid oligodendroglial/astrocytic features, J.
Neuropathol. Exp. Neurol., 2003, 62: 1118-1128.
86. Schmidt RE, Dorsey DA, Beaudet LN, Parvin CA, Zhang W, Sima AAF. Experimental rat
models of types I and II diabetes differ in sympathetic neuroaxonal dystrophy, J
Neuropathol. Exp. Neurol., 2004, 63: 450-460.
87. Carroll SL, Byer SJ, Dorsey DA, Watson MA, Schmidt RE. Ganglion-specific patterns of
diabetes-modulated gene expression are established in prevertebral and paravertebral
sympathetic ganglia prior to the development of neuroaxonal dystrophy. J.
Neuropathol. Exp. Neurol., 2004, 63:1144-1154.
88. Sun S-W, Neill JJ, Liang H-F, He YY, Schmidt RE, Hsu CY Neil JJ, Song S-K. Formalin
fixation alters water diffusion coefficient magnitude but not anisotrophy in infarcted
brain, Magnetic Resonance in Medicine, 2005, 53:1447–1451.
89. Schmidt RE, Dorsey DA, Beaudet LN, Parvin CA, Yarasheski KE, Smith SR, Williamson
JR, Peterson RG, Oates PJ. A potent sorbitol dehydrogenase inhibitor exacerbates
autonomic neuropathy in rats with streptozotocin-induced diabetes. Exp. Neurol.,
2005, 192:407-419.
90. Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois MR,
Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM,
Schmidt RE, Saffitz JE, Semenkovich CF, Abel ED, Kelly DP. The transcriptional coactivator PGC-1 as a critical transducer of postnatal growth and energy metabolic
maturation programs, PLoS, 2005; 3:e101.
91. Le N, Nagarajian R, Wang J, Araki T, Schmidt R, Milbrandt J. Analysis of congenitally
hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell
differentiation. Nature Neuroscience., 2005; 8:932-40.
92. Lenschow DJ, Giannakopoulos NV, Gunn LJ, Johnston C, O’Guin AK, Schmidt RE,
Levine B, Virgin, HW IV. Identification of interferon-stimulated gene 15 as an
antiviral molecule during Sindbis virus infection in vivo. J Virol 79:13974-13983,
2005.
93. Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Szabolcs F, Welling C, Murray J,
Schmidt RE, Herrerra PL, Permutt MA. Mice conditionally lacking the Wolfram gene
(Wfs1) in pancreatic islet -cells exhibit diabetes as a result of enhanced endoplasmic
reticulum (ER) stress and apoptosis. Diabetologia 48:2313-2321, 2005.
94. Schmidt RE, Dorsey DA, Parvin CA, Beaudet LN. Sympathetic neuroaxonal dystrophy in
the aged rat pineal gland. Neurobiol Aging, 2006; 27:1514-1523.
95. Perry A, Schmidt RE. Cancer Therapy-Associated CNS Neuropathology: An Update and
Review of the Literature. Acta Neuropathol, 2006; 111:197-212.
Robert E. Schmidt, M.D., Ph.D.
Page 7
96. Pandey N, Schmidt RE, Galvin JE. The alpha-synuclein mutation E46K promotes
aggregation in cultured cells. Exp Neurol 2006, 197:515-520.
97. Dubberke ER, Tu B, Rivet DJ, Storch GA, Apisarnthanarak A, Schmidt RE, Weiss S,
Polish LB. Acute Meningoencephalitis Caused by Adenovirus Serotype 26. J
Neurovirol, 2006, 12:235-240.
98. Yang X-F, Kennedy BR, Lomber SG, Schmidt RE, Rothman SM. Cooling produces
minimal neuropathology in neocortex and hippocampus. Neurobiol Disease 2006,
23:637-643.
99. Baloh RH, Schmidt RE, Pestronk A, Milbrandt J. Altered axonal mitochondrial transport
in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. J
Neurosci. 2007, 27:422-430.
100. Budde, M.D., Kim, J.H., Liang, H.F., Schmidt, R.E., Russell, J.H.,
Cross, A.H., Song, S.K. Toward Accurate Diagnosis of White Matter
Pathology Using Diffusion Tensor Imaging. Magnetic Resonance in Medicine 2007,
57:688-695.
101. Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A,
Levine B, Schmidt RE, Garcia-Sastre A, Leib DA, Pekosz A, Knobeloch K-P, Horak I,
Virgin HW, IV. ISG15 functions as a critical antiviral molecule against both influenza
and herpes viruses. Proc Natl Acad Sci USA 2007, 104:1371-1376.
102. Kim JH, Loy DN, Liang H-F, Trinkaus K, Schmidt RE, Song S-K. Noninvasive
diffusion tensor imaging of evolving white matter pathology in a mouse model of acute
spinal cord injury. Magnetic Resonance Medicine 2007, 58:253-260.
103. Loy DN, Kim JH, Xie M, Schmidt RE, Trinkaus K, Song S-K. Diffusion tensor imaging
predicts hyperacute spinal cord injury severity. J Neurotrauma 2007, 24:979-990.
104. Schmidt RE, Green KG, Dorsey DA, Parvin CA, Lee J-M, Xiao Q, Brines M.
Erythropoietin and its carbamylated derivative prevent the development of experimental
diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice.
Experimental Neurology, http://dx.doi.org/10.1016/j.expneurol.2007.09.018.
105. Ryu EJ, Wang JYT, Le N, Gustin JA, Schmidt RE, Milbrandt J. Misexpression of
Pou3f1 results in peripheral nerve hypomyelination and axonal loss. J Neurosci, in
press.
106. Sun SW, Liang H-F, Schmidt RE, Cross AH, Song S-K. Selective vulnerability of
cerebral white matter in a murine model of multiple sclerosis detected using diffusion
tension imaging. Neurobiol Disease 2007, 28:30-38.
107. Malik I, Turk J, Mancuso DJ, Montier L, Wohltmann M, Wozniak D, Schmidt RE, Gross
RW, Kotzbauer PT. Disrupted membrane homeostasis and accumulation of
ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy due to
PLA2G6 Mutations. Am J Pathol, in press.
INVITED REVIEWS, CHAPTERS, OTHER PUBLICATIONS:
1. Schmidt RE: Pathology of the Sympathetic Nervous System. In: The Pathology of the
Aging Human Nervous System. Duckett, S. (Ed.), Lea and Febiger, Philadelphia, 1991,
p. 431-442
Robert E. Schmidt, M.D., Ph.D.
Page 8
2. Schmidt RE: Neuroaxonal dystrophy in the sympathetic autonomic ganglia of aged rodents
and man. In: Advances in the Innervation of the Gastrointestinal Tract. Holle GE,
Wood JD (Eds.), Elsevier, Amsterdam, 1992, p. 645-655
3. Schmidt RE: The role of nerve growth factor in the pathogenesis and therapy of diabetic
neuropathy. Diabetic Medicine 1993;10(Suppl 2):105-135
4. Schmidt RE: The innervation of the alimentary tract of diabetic animals - An experimental
model of diabetic autonomic neuropathy. In: Diabetes Mellitus and its Complications.
An Update. Sharma AK, Galadari I, Abdulrazzaq Y, Behara M, Mehra NK,
Manchanda SK (Eds.) MacMillan India, LTD., 1993, p. 303-314
5. Schmidt RE: Demyelinating Diseases In: Principles and Practice of Neuropathology.
Nelson JS , Parisi JE, Schochet SS (Eds.), Mosby, St. Louis, 1993; p361-397
6. Schmidt RE: Diseases of the peripheral nervous system. In: Principles and Practice of
Neuropathology. Nelson JS , Parisi JE, Schochet SS (Eds.), Mosby, St. Louis, 1993, p.
561-595
7. Schmidt RE: Neuroaxonal dystrophy in aging rodent and human sympathetic autonomic
ganglia -- Synaptic pathology as a common theme in neuropathology. Adv Pathol Lab
Med, Vol 6, Weinstein RS (Ed.), Mosby, St. Louis, 1993, p. 505-522
8. Schmidt RE: The neuropathology of human sympathetic autonomic ganglia. Microscop
Res. Tech, 1996; 35:107-121.
9. Schmidt RE: Neuroaxonal dystrophy in aged and diabetic sympathetic ganglia.
Neuropathology, 1996; 16:83-84.
10. Schmidt RE: Synaptic dysplasia in sympathetic autonomic ganglia. J Neurocytol, 1997;
25:777-791.
11. Bruch LA, Schmidt RE. Pathology of the Autonomic Nervous System, In: Handbook of
Clinical Neurology, Eds. PJ Vinken and GW Bruyn, Autonomic Nervous System Part II
(Ed. O Appenzeller) Vol. 75, Elsevier Publishers, Amsterdam, 2000; pp 1-52.
12. Schmidt RE. The neuropathology of the aging autonomic nervous system. In: The
Pathology of the Aging Human Nervous System, Ed. S. Duckett. Oxford University
Press, New York, 2001, p. 431-448.
13. Schmidt RE: Age-related sympathetic ganglionic neuropathology. Human pathology and
animal models. Autonomic Neuroscience: Basic and Clinical 2002; 96: 63-72.
14. Schmidt RE. Neuropathology and pathogenesis of diabetic autonomic neuropathy. In:
Neurobiology of Diabetic Neuropathy, Ed. Tomlinson, DR, 2002, p. 267-292.
15. Fernyhough P, Schmidt RE. Neurofilament phosphorylation—mechanisms and
consequences. In: Neurobiology of Diabetic Neuropathy, Ed. Tomlinson, DR, 2002, p.
115-144.
16. Schmidt RE. Diseases of CNS myelin. In: Principles and Practice of Neuropathology.
J.S. Nelson, Ed. Oxford University Press, New York, 2003, pp. 246-266.
17. Schmidt RE. Non-neoplastic diseases of the peripheral nervous system. In: Principles and
Practice of Neuropathology. Oxford University Press, New York, 2003, pp. 497-524.
18. Schmidt RE. Histopathology of Diabetic Autonomic Neuropathy. In: Diabetic
Neuropathy. Eds. FA Gries, PA Low, DR Tomlinson, D Ziegler. George Thieme
Verlag, Stuttgart, 2003, pp. 87-91.
19. Schmidt RE. Age-Related Sympathetic Autonomic Neuropathology-Human Studies and
Experimental Animal Studies. In: Autonomic Nervous System in Old Age: Bridging
Basic and Clinical Perspectives, Eds: Kuchel GA, Hof P., 2004, pp 1-23.
Robert E. Schmidt, M.D., Ph.D.
Page 9
20. Schmidt RE. Infantile Neuroaxonal Dystrophy (INAD). In: The NORD Guide to Rare
Disorders, Lippincott, Williams & Wilkins. Philadelphia, PA, 2003, pp 634-635.
21. Schmidt RE. Neuropathy: Diabetic and Other Metabolically-induced Neuropathies. In:
The Encyclopedia of Neuroscience, in press.
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