METHODICAL INSTRUCTIONS FOR INDIVIDUAL WORK OF STUDENTS IN PREPARATION FOR PRACTICAL CLASSES Subject NEUROLOGY Topic. Neurosyphilis. Neurologic manifistations of polymyositisdermatomyositis Year Faculty IV Medical 1.Topicality: Diseases studied at these classes have different aetiology, pathogenesis and clinical picture. Some of the manifestations or complications are the neurological syndromes in these diseases. But these diseases are quite widespread and result in disablement and bad complications of the patients. Therefore to prescribe a specific treatment a doctor has to estimate the disease on the basic of diagnostic criteria in proper time. 2. Specific purposes: 1. To learn the classifications principles of infectious diseases of nervous system 2. To learn the clinic of neurosyphilis, neurologic impairments of polymyositis- dermatomyositis 3. To interpret the forms of neurosyphilis. 4. Make up the schemes of the treatment, prevention and prophylactic of the neurologic diseases of the nervous system. 3. Basic knowledge, skills and competences which are necessary for topic studying: № 1 Subject Anatomy 2 3 Physiology Anatomical pathology 4 Physiopathology 5 Microbiology 6 Pharmacology Information to learn Anatomy of the brain, the spinal cord and the brain membrane Medullispinal fluid, its circulation and its structure. Stages of the inflammatory and degenerate processes, morphological changes in the nervous system during inflammatory and degenerate processes Aetiology and pathogenesis of the inflammatory and degenerate diseases of the nervous system, systemic diseases of the connective tissue, kinds and stages of the inflammatory process, pathological syndromes of the liquor system abnormalities. The characteristic of the causative agents of the nervous system inflammatory diseases. The treatment principles of the inflammatory diseases, degenerate diseases of the nervous system. Medications from the group of antibiotics, antisensitizers, diuretics, anticholinesterase drugs. 4. Assignments for individual work during preparation for the classes The list of the basic terms, characteristics which students must learn during the preparation for the classes: - Peripheral paresis Central paresis bulbar syndrome alternating syndrome meningeal symptom polineuropathies numerous mononeuropathies myotonic syndrome syndromes of dissociation in liquor (cellular-protein and protein-cellular) The list of theoretical questions: 1. Neurosyphilis. Early neurosyphilis (mesodermal): generalized syphilitic meningitis, meningovascular syphilis, gummas of the brain and the spinal cord, delitescence asymptomatic meningitis (liquorsyphilis). 2. Late neurosyphilis (parenchymatous): tabes dorsalis, progressive paralysis. Diagnostics and treatment methods. 3. Neurologic impairments of polymyositis – dermatomyositis: aetiology, pathogenesis, clinical presentations (the syndrome of the skeleton muscles affection, myofascitis pain syndrome, myotonic syndrome, Raynaud's syndrome); neurologic impairments (affection of CNS, vegetative impairments, hypothalamic dysfunction, entrapment neuropathy), additional methods of examination, differential diagnostics, treatment, prophylaxis. The list of the necessary practical skills that are to be mastered at the classes: 1. Individual examination of the patients with neurological pathology, making up the case history. 2. Estimating the main neurological syndrome in a patient. 3. Substantiation of the niveau diagnosis at the examined patient. 4. Carrying out the differential diagnostics. 5. Confirmation of the estimated clinical diagnosis 6. Estimating of the aetiology of the disease, peculiarities of the pathogenesis, the course of the disease and its complications at the examined patient. 7. Confirmation of the treatment prescribed to the patient. 8. The prognosis estimating of the disease course at the given patient. 5. Student’s self-preparation curriculum: 1. To learn theoretical questions of the subject 2. To know the methods of the examination of the neurological state 3. To acquaint with the tests and situational task (collection of the tests and tasks). 6. Materials for self-control 1. To draw the table with a picture of the clinical forms, stages, symptoms and syndromes, methods of diagnostics and treatment of the neurosyphilis and neurological impairments of the polymyositis – dermatomyositis. 2. To find right answers to the tests and situational tasks on the topic. Information Sources Lecture 1. Shcrobot S.I., Hara I.I. Neurology in lecture (Selected lectures) . Ternopil, TSMU, «Ukrmedknyha», 2008. 319 p. 2. Reinhard Rohkamm. Color Atlas of Neurology © 2004 Thieme. 440 p. 3. Crash course Neurology by Anish Bahra and Katia Cikurel. Copyright 2006, Elsevier, Inc. 244 p. 4. Adams and Victors. Principles of neurology. © 2005 McGraw-Hill . Medical Publishing Division. 5. Mayo Clinic Internal Medicine Review 2006-2007. Chapter 18. Editor-in-Chief Thomas M. Habermann, MD