ACADEMIC CAREER
01/2011-present Associate Professor
Department of Biomedical Engineering, Florida International University, Miami, USA
08/2006-01/2011 Assistant Professor
Department of Biomedical Engineering, Florida International University, Miami, USA
01/2004-08/2006 Research Officer
Nanomedicine/Bioelectronics Group, Biotechnology Research Institute (Montreal),
Canada National Research Council
01/2002- 12/2003 Research Associate
Department of Chemistry & ADNAvance Technologies Inc. University of
Saskatchewan.
04/2000-10/2001 Postdoctoral Research Fellow (with Prof. Grant Mauk)
Department of Biochemistry and Molecular Biology, School of Medicine , University of
British Columbia
09/1990-03/1993 Professional Engineer
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Beijing Materials Research Institute, China
EDUCATION
2000-2001 Postdoc in Molecular Biology and Biochemistry, School of Medicine
University of British Columbia
1997-2000 Ph. D. in Applied Chemistry
Kumamoto University, Japan.
1993-1997 M. Sc. in Electrochemistry
Kumamoto University, Japan.
1986-1990 B. Eng.
in Material Engineering,
Hebei Polytechnic University, China.
RESEACH INTERESTS
Key words: Nanomedicine, biosensor, point of care testing, Alzheimer disease, biofuel cell, nanaomedicine, nanoparticles, devices, implantable sensors, cancer biomarkers,
DNA mutants, single cell measurement, nanotoxicity, enzymatic biosensors, environmental sensor, SPR sensor, biofunctionalization, molecular electronics,
BioMEMs, etc.
 Development of nanomaterial based biosensing system for biological component analysis-examples including DNA biosensor, environmental toxin detector, cancer biomarkers, Alzheimer disease biomarkers, enzymatic biosensor and drug sensor.
 Point-of-Care-Testings for Clinical Applications
 Development of electric cell impedance immuno-sensor system for the rapid and simultaneous identification of pathogens.
 Micro/nano sensor for implanting and single cell measurements
 DNA and hemoprotein redox properties
 Electrophysiology and Bioelectrochemistry
 Enzymatic biofuel cell
 Toxicity assay of nanomaterials
 Biomolecules based electronics
 Nanoparticles based biomarkers
 Bio-NEMS/MEMS
EDITORIAL SERVICE
2011-present Associate Editor : Biosensors Journal, Ashdin Publishing.
2010-present Associate Editor : Applied Biochemistry and Biotechnology, Springer.
2009 Guest Editor : Special Issue on Biomedical Engineering, American Journal
Of Biomedical Science. New World Publishing International, Inc (NWPII)
Editorial Board:
2011-present International Journal of Nanomedicine
2010-present Chemical Sensors
2010-present Journal of Nanoscience Letters
2009-present American Journal of Biomedical Science
2008-2010 Nanomedicine: Nanotechnology, Biology and Medicine
PROFESSIONAL HONORS, PRIZES, FELLOWSHIPS
2011
2011
2010
2009
International Resource Person Award by the National Dairy Research
Institute of Indian
Kauffman Professor Award ($ 15,000)
FASEB MARC Travel Award ($ 1,850)
Kauffman Professor Award ($ 15,000)
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2008
2001-2002
1995-2000
1994-1995
FIU Faculty Research Award ($ 15,000)
CIHR/UMDI Postdoctoral Fellowship ($ 38,000)
Japanese Government (Monbusho) Fellowship ($ 110,000)
Rotary Suzuki Scholarship ($ 8,000)
LIST OF PUBLICATIONS:
H index by 2011: 16
Book & Book Chapters
1. E. Hondroulis, C.-Z. Li , “ Electrical Impedance Biosensors in Nanotoxicity Studies” in the book “Nanotoxicity: Methods and Protocols” in the series Methods in Molecular
Biology , 2010, Eds Joshua J. Reineke, John Walker, Springer Science and Business
Media, New York, USA.
2. S. Alwarappan, C.-Z. Li , "Nanomaterials Incorporated Bioelectronics", in Wiley
Encyclopedia of Industrial Biotechnology, Bioprocess, bioseperation and cell technology,
Ed. Michael C. Flickinger, 2010, (ISBN: 978-0-471-79930-6), John Wiley & Sons
3. C.-Z. Li (editor), A. McGoron, W. Lin, IFMBE Proceedings (ISBN: 978-3-642-01696-7),
Vol. 24 (2009), Springer, Heidelberg, Germany.
4. Andy. X. Sun, CZ. Li “Carbon Nanotubes and Nanowires Based Biosensors” in "Smart
Biosensor Technology", Editor George K. Knopf, CRC Press. Chapter 12, 291-333,
(2006).
5. C.-Z. Li , Y-T. Long, T. C. Sutherland, J.S. Lee and H.B. Kraatz, “DNA Electronic
Biosensors Based on DNA SelfAssembled Monolayer on Gold Electrodes”, in “The
Frontiers of Biochip Technologies”, Editor Dr. Jing Cheng, Kluwer Academic Publishers,
Chapter 5, 270-287, (2005)
Recent Publications
6. D. Carvajal, R. Guduru, L. Lagos, Y. Katsenovich, C.-Z. Li , Assessment of the
Resistance to Uranium (VI) Exposure by Arthrobacter sp. Isolated from Hanford Site
Soil, Geomicrobiology Journal (IF 2.104), accepted, 2011.
7. S. Prabhulkar, H. Tian, X, Wang, C-Z. Li , Engineered Proteins: Redox properties and their applications, Antioxidants and Redox Signaling ( IF 8.51), accepted, 2011.
8. S. Prabhulkar, R. Piatyszek, J. R. Cirrito, Z-z. Wu, C.-Z. Li, Microbiosensor for
Alzheimer’s Disease Diagnostics: Detection of Amyloid Beta Biomarkers, Journal of
Neurochemistry (IF 4.480), accepted, 2011.
9. Z.-Z. Wu, M. Zhu, W. S. Kisaalita, L. Wang, Y.P. Zhao, Y. Lin, Q. Huang, Y. Liao, C.-Z.
Li , Fabrication of Arrayed Topographic Substrates and Their Effects on the
Electrobiophysical Properties of Neuronal Cells, Chinese Journal of Sensors and
Actuators, 2011, 24, 468-474.
10. L.-G. Zhang, Z.-Z. Wu, Z.-q. Song, Q.-p. Huang, Y.-j. Liao, C.-Z. Li, Fabrication of threedimensional microwell patterns and their integration with C17.2 neural stem cells,
Chinese Journal of Biomedical Engineering , in press.
11. C. Urbanek, S. Goodison, M. Chang, S. Porvasnik, N. Sakamoto, C.-Z. Li , C. Ketcham,
S. Boehlein, C. J Rosser, Detection of antibodies directed at M. hyorhinis p37 in the serum of men with newly diagnosed prostate cancer, BMC Cancer (IF 2.74), 2011, 11,
233.
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12. E. Hondroulis, C.-Z. Li , Impedance based Nanotoxicity Assessment of Graphene
Nanomaterials at the Cellular and Tissue Level, Analytical Letters (IF 1.344), 2011, in press.
13. C.-Z. Li, K. Vandernberg, S. Prabhulkar, X. Zhu, L. Schneper, K. Methee, C.J. Rosser,
E. Almeide, Paper Based Point-of-Care Testing Disc for Multiplex Whole Cell Bacteria
Analysis, Biosensors and Bioelectroncs (IF 5.483), 2011, 26, 4342-4348.
14. Z. Zhang, A. J. McGoron, E. T. Crumpler, C.-Z. Li , Co-culture based blood-brain barrier in vitro model, a tissue engineering approach using immortalized cell lines for drug transport study, Applied Biochemistry and Biotechnology (IF 1.879), 2011, 163, 278-295.
15. C. Liu and C.-Z. Li , Surface Engineering of Graphene-Enzyme Nano Composites for
Miniaturized Biofuel Cell, IEEE Transactions on Nanotechnology (IF 2.15), 2011, 10 (1).
59-62.
16. S. Prabhulkar, C.-Z. Li , Assessment of Oxidative DNA Damage and Repair at Single
Cellular Level via Real-time Monitoring of 8-OHdG Biomarker, Biosensors and
Bioelectronics (IF 5.483), 2010, 26 (4), 1743-1749.
17. E. Hondroulis, C. Liu, C.-Z. Li , Whole Cell Based Electrical Impedance Sensing
Approach for Rapid Nanotoxicity Assay, Nanotechnology (IF 3.23), 2010, 31, 315103 (9 pgs). Highlighted b y the news at “nanotechweb.org”; http://nanotechweb.org/cws/article/lab/43407; http://www.nanotechnology.org.in/; http://lib.bioinfo.pl/meid:249247/pmid; http://worldwidescience.org/.
18. S. Alwarappan, C. Liu, A. Kumar, C.-Z. Li , Enzyme Doped Graphene Nanosheets for
Enhanced Glucose Biosensing, Journal of Physical Chemistry C (IF 4.522), 2010, 114
(30), 12920-12924.
19. R. Banerjee, Y. Katsenovich, L. Lagos, M. Senn, M. Naja, V. Balsamo, K.H. Pannell, C.-
Z. Li , Functional Magnetic Nanoshells Integrated Nanosensor for Trace Analysis of
Environmental Uranium Contamination, Electrochimica Acta (IF 3.642), 2010, 55(27),
7897-7902.
20. R. Banerjee, Y. Katsenovich, L. Lagos, M. McIintosh, X. Zhang, C.-Z. Li , Magnetic
Nanoparticles in Biology and Nanomedicine, Current Medicinal Chemistry (IF 4.90),
2010, 17 (27), 3120-3141.
21. Z. Zhang, A. Conway, A. Salamone, E. T. Crumpler, X. Zhang and C.-Z. Li , Amphiphilic
Copolymers for Liquid Bandage Application Studies, Frontiers in Bioscience (IF 3.74),
2010, E2, 1123-1133.
22. N. Zhao, Y. He, X. Mao, Y. Sun, X. Zhang, C.-Z. Li , Y. Lin, G. Liu, Electrochemical
Assay of Active Prostate-Specific Antigen (PSA) using Ferrocene-Functionalized
Peptide Probes, Electrochemical Communications (IF 4.846), 2010, 12 ,471 –474.
23. W. Chen, Y. Li, G. Yu, Z. Zhou,
A Simple Approach to Realize Semiconductor-Half
C.-Z. Li , Z. Chen,
Metal
Metal Transition in Boron Nitride Nanoribbons, Journal of American Chemical Society
(IF 9.019), 2010, 132, 1699-1705. Highlighted by the news at www.nanowerk.com. http://www.nanowerk.com/spotlight/spotid=15647.php.
24. C. Liu, S. Alwarappan and C.-Z. Li, Design and Characterization of Novel
Membraneless Enzymatic Biofuel Cell Based on Graphene Nanosheets, Biosensors and Bioelectronics (IF 5.483), 2010, 7, 1829-1833.
25. B. Chen, Y. Xiao, C. Liu, C.-Z. Li , F. Leng, DNA Linking Number Change Induced by
Sequence-Specific DNA-Binding Proteins, Nucleic Acids Research (IF 7.836), 2010,
38(11), 3643-3654.
26. S. Alwarappan, C.-Z. Li, Simultaneous Detection of Dopamine, Ascorbic Acid and Uric
Acid at Electrochemically Activated Carbon Nanotube Biosensors, Nanomedicine,
Nanotechnology, Biology and Medicine (IF 5.440), 2010, 6, 52-57.
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PATENTS
1. S. Prabhulkar, C.Z. Li, “Electrochemical Micro-Immunosensor for Direct Detection of
Amyloid Beta”, Provisional Patent, Filed in June, 2010. Serial No: 61/332124.
2. J.S. Lee, H.-B. Kraatz, C.-Z. Li, Y.-
T. Long, “Nucleic Acid Mismatch Detection.”
WO
2004079001 .
3. C.-Z. Li, Y.-T. Long, H.B. Kraatz, J.S. Lee, “Electrochemical detection of DNA binding.”
WO 2005001122 .
4. C.-Z. Li, and J.H. Luong “Impedance sensing of DNA binding drugs using gold substrates modified with gold nanoparticles” WO2006021091.
5. B. Allain, C.Z. Li, Keith B. Male, J.HT.Luong R. Mandeville and C. Xiao “Nethod and apparatus for the detection of microorganisms ” WO2005088287.
International Appl. No.
PCT /CA2005/000411.
6. Long, Y.-T., Li, C.-Z, Kraatz H. B. and Lee, J. S.. Electrochemical detection of SNP in
DNA by using AC impedance spectroscopy. (2006) US. 2006275786.
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