HISTOLOGY WRITTEN EXAM III MULTIPLE CHOICE: CHOOSE THE SINGLE BEST ANSWER. EACH ANSWER IS WORTH I POINT EACH FOR THE WRITTEN EXAM 1. The major site of concentration of the filtrate is: A. Thick ascending limb B. Proximal tubule C. Collecting tubule D. Bowman's space E. Peritubular capillaries 2. A characteristic exclusive to the primary spermatocyte is: A. Lack of chromosomal crossing over during differentiation B. Occupation of both the basal and adluminal compartments C. It is the smallest of the male germ cells D. Formation of one secondary spermatocyte E. Total loss of cytoplasm 3. The labia minora contain each of the following EXCEPT: A. Lymphatics B. Keratinizing stratified squamous epithelium C. Fat D. Nerves E. Elastic fibers 4. Each of the following is true regarding Brunner's glands EXCEPT: A. They are not associated with "M" cells. B. They lie in the submucosal region. C. They are typically absent from the wall of the colon. D. They produce a serous secretion rich in digestive enzymes. E. They empty their secretions into the crypts of Lieberkuhn. 5. Glycogen is present in the vaginal mucosa in largest quantities during the: A. Post-menopause phase B. Late secretory phase C. Mid secretory phase D. Proliferative phase E. Menstrual phase 6. Collections of renal cortical tissue found between the medullary pyramids are called: A. Cortical rays of Henle B. Medullary rays C. Renal columns of Berlin D. Interlobular cortex E. Minor calyces -1- MATCHING: For each numbered item in COLUMN 1, choose the letter of the most closely related item in COLUMN 2. Each answer can be used once, more than once. or not at all COLUMN 1 7. Intermediate trophoblast 8. Ovulation 9. Syncytiotrophoblast 10. Granulosa cells 11. Corpus luteum of pregnancy COLUMN 2 A. Stigma B. Placental Lactogen C. Colloid droplets D. Wolffian duct E. Call-Exner body 12. The pampiniform plexus of veins helps control: A. Male libido B. Testicular temperature C. Testicular mass D. Vascularization of the spermatic cord E. Male secondary sexual characteristics 13. All of the following are lined by simple epithelia EXCEPT: A. Hymen B. Endometrium C. Fallopian tube D. Surface epithelium of ovary E. Endocervix 14. 55. The cells primarily responsible for formation of the blood-testis barrier are the: A. Primary spermatocytes B. Leydig cells C. Sertoli cells D. Capillary endothelial cells E. Myoepithelial cells 15. Which part of the placenta is of maternal origin? A. Hofbauer cells B. Decidua basalis C. Chorion laeve D. Chorion frondosum E. Amnion 16. The major site of reabsorption of the glomerular filtrate is: A. Distal convoluted tubule B. Loop of Henle C. Thick ascending limb D. Proximal tubule E. Collecting tubules -2- 17. The golgi, cap, acrosomal and maturation phases are part of: A. Perimeiosis B. Spermiation C. Mitosis D. Meiosis E. Spem,iogenesis MATCHING: For each numbered item in COLUMN 1, choose the letter of the most closely related item in COLUMN 2. Each answer can be used once, more than once or not all. COLUMN I 18. Collecting tubule 19. Proximal tubule 20. Thick ascending limb 21. Interstitial cells COLUMN 2 A. Angiotensin II B. "Diluting segment" C. Prostaglandin production D. Brush border E. Principle and intercalated cells 22. The normal weight of each adult kidney is approximately: A. 300 gm B. 80 gm C. 250 gm D. 200 gm E. 150 gm 23. Its muscularis has three layers: A. Myometrium B. Vulva C. Vagina D. Endometrium E. Fallopian tube 24. The segment of the nephron present in all zones of the kidney is: A. Thick descending limb B. Thick ascending limb C. Distal convoluted tubule D. Thin limbs E. Collecting tubule/duct 25. The ductus epididymis: A. Is traversed by the urethra. B. Begins at the rete testis C. Possesses motile cilia on the epithelial cells. D. Secretes a large volume of fluid into the tubular lumen. E. Is lined by pseudostratified columnar epithelium. -3- 26. The site of the juxtaglomerular cells is: A. Macula densa B. Extraglomerular mesangial cells C. Walls of afferent and efferent arterioles D. Intraglomerular mesangial cells E. Interstitium of the hilar region 27. Each of the following is a component of the spermatic cord EXCEPT: A. Pampiniform plexus B. Bulbourethral glands C. Cremaster muscle D. Vas deferens E. Testicular artery 28. The umbilical cord contains each of the following EXCEPT: A. Mast cells B. Fibroblasts C. Lymphatics D. Smooth muscle cells E. Elastic fibers 29. The enterohepatic circulation is important in the recirculation of bile from the digestive tract to the liver for processing. From which portion of the gastric tract is bile absorbed for this recirculation? A. Rectum B. Ileum C. Jejunum D. Duodenum E. Colon MATCHING: For each numbered organ in COLUMN 1, choose the letter of the most closely related secretory product in COLUMN 2. Each answer can be used once, more than once, or not at all. COLUMN 1 COLUMN 2 30. Seminal vesicle A. Zinc 31. Bulbourethral gland B. Glucose 32. Prostate gland C. Testosterone D. Sialoprotein E. Fructose 33. The first meiotic division in the ovum is arrested at A. Anaphase B. Prophase C. Prometaphase D. Metaphase E. Telophase -4- 34. Which ONE of the following is NOT a component of the gastric mucosa? A. Intrinsic factor secreting cells B. Enteroendocrine cells C. Zymogen secretory cells D. Epithelial stem cells E. Goblet cells 35. The overall histologic structure of the appendix is similar to that of the colon EXCEPT that the appendix lacks: A. Absorptive cells B. Goblet cells C. Muscularis mucosa D. Taenia coli E. Muscularis extema 36. The cytotrophobiastic cells: A. Secrete progesterone B. Secrete estrogen C. Secrete placental lactogen D. Do not secrete hormones E. Secrete chorionic gonadotropin 37. Each of the following structures is entirely lined by transitional epithelium EXCEPT: A. Calyces B. Renal pelvis C. Female urethra D. Distal ureter E. Proximal ureter 38. Blood vessels develop in the chorionic villi at the stage of: A. Secondary villus B. Tertiary villus C. Trophoblastic stem villus D. Definitive villus E. Primary villus 39. The _________ of the spermatozoa contains the nucleus, acrosome and plasmalemma. A. Head B. Middle piece C. Neck D. Principal piece E. End piece -5- 40. Concurrent heat exchange involves: A. Direct flow of blood through the tubuli recti B. Venous blood being cooled by arterial blood C. Testicular descent into the scrotum D. Closure of the spermatic cord E. Arterial blood being cooled by venous blood 41. Aggregates of lymphatic nodules are routinely found in which of the following tissues? A. Duodenum B. Jejunum C. Esophagus D. Colon E. Ileum 42. The efferent arterioles of the juxtamedullary nephrons gives rise to: A. Peritubular capillaries B. Glomerular capillaries C. Ascending vasa recta D. Arcuate veins E. Descending vasa recta 43. The zona pellucida first appears in: A. Primary follicles B. Tertiary follicles C. Antral follicles D. Secondary follicles E. Primordial follicles 44. Which of the following is TRUE regarding arcuate arteries? A. Gives rise to the efferent arteriole. B. Directly branches off the hilar renal artery C. Defines the border between outer and inner stripe D. Extends into the renal papilla E. Defines the border between cortex and medulla 45. Which of the following is found exclusively in the renal medulla? A. Distal convoluted tubules B. Thin loops of Henle C. Afferent arterioles D. Collecting ducts E. Proximal convoluted tubules 46. Corpus albicans is the end result of: A. Atretic primordial follicle B. Atretic primary follicle C. Corpus luteum D. Atretic antral follicle E. Corpus fibrosum -6- 47. Hypothalamic GNRH causes release of pituitary LH. LH stimulates: A. Leydig cells B. Sertoli cells C. Type A spermatogonia D. Interstitial cells E. Spermatids 48. During the secretory (luteal) phase, the endocervical mucus: A. Contains numerous leukocytes B. Is alkaline C. Is watery D. Is profuse E. Contains numerous stromal balls 49. The chief cells in the gastric glands are responsible for production of? A. Hydrochloric acid B. Mucin C. Gastrin D. Pepsinogen E. Gastric intrinsic factor 50. Skene's glands are the female counterparts of the male: A. Littre's glands B. Prostate C. Bulbourethral glands D. Cowper's glands E. Seminal vesicles MATCHING: For each numbered item in COLUMN 1. choose the letter of the most closely related item in COLUMN 2. Each answer can be used once, more than once, or not at all. COLUMN 1 51. Cardiac glands 52. Auerbach's plexus 53. Esophageal glands 54. Central lacteal 55. Peyer's patches 56. Meissner s plexus COLUMN 2 A. Submucosa B. Lamina propria C. Muscularis extema D. Epithelium E. Muscularis mucosa 57. The clitoris has: A. Two conjoined corpora cavemosa B. Two conjoined corpora spongiosa C. Apocrine glands D. Two conjoined corpora cavemosa and one corpus spongiosum E. Sebaceous glands -7- 58. During an autopsy, biopsies are taken from several parts of the GI tract. In which structure will an epithelium be seen in which every surface cell is capable of secreting mucus? A. Duodenum B. Stomach C. Ileum D. Transverse colon E. Esophagus 59. The breast: A. Lacks sebaceous glands in the nipple B. Has ducts lined by a ciliated columnar epithelium C. Is composed mostly of adipose and fibrous connective tissue D. Contains the ligaments of Montgomery E. Has a different structure in males as compared to females prior to puberty -8- HISTOLOGY PRACTICAL EXAM III MULTIPLE CHOICE: CHOOSE THE SINGLE BEST ANSWER. EACH ANSWER IS WORTH 2 POINTS EACH FOR THE PRACTICAL EXAM 1. Identify this part of the male reproductive tract: A. Rete testis B. Epididymis C. Vas deferens D. Ductuli efferentes E. Prostate 2. This structure: A. Is derived from the mother B. Is rich in lymphatics and blood vessels C. Usually contains cytotrophoblastic cells D. Is the innermost lining of the embryonic cavity E. Fuses with the decidua basalis 3. The antigen presenting cells in this epithelium are known as? A. Macrophages B. T- Lymphocytes C. M cells D. Langerhans cells E. Epithelial reticular cells 4. This structure is a/an: A. Wolffian duct remnant B. Nabothian cyst C. lymphatic vessel D. Artifact E. Implantation site 5. The arrow is in the lumen of which structure? A. Gastric gland B. Crypt of Lieberkuhn C. Brunner's gland D. Esophageal gland E. Plica circularis 6. Identify this tissue: A. Esophagus B. Stomach C. Jejunum D. Large intestine E. Appendix -9- 7. This tissue: A. Is under the direct influence of estrogen B. Is equivalent to the prostate in the male C. Undergoes squamous metaplasia D. Contains prominent spiral arterioles E. Is seen following ovulation 8. This tissue: A. Produces the cytotrophoblast cells B. Accumulates lipofuscin during the aging process C. Is the preferred site of implantation D. Has cells that are responsive to estrogen E. Secretes fructose 9. Identify this tissue: A. Fallopian tube B. Appendix C. Vas deferens D. Ureter E. Cervix 10. Which of the following is true of this cell? A. It produces testosterone B. It has a phagocytic function C. It is the largest of the male germ cells D. It contains stereocilia E. It responds to prolactin 11. What is the major function of this region of the gastrointestinal tract? A. Digestion of proteins B. Absorption of chylomicrons C. Production of alkaline secretion D. Absorption of water E. Combating antigenic penetration of this epithelium 12. This structure: A. Carries oxygenated blood B. Lacks a subintimal elastic layer C. Has a vasa vasorum D. Has two muscular layers in its wall E. Opens into the intervillous spaces 13. This tissue: A. Serves as a reservoir for sperm storage B. Contains no glands C. Is responsive to progesterone D. Has ducts emptying into the urethra E. Produces androgen-binding protein - 10 - 14. The spermatozoa in this area of the testis next enter the: A. Epididymis B. Ductus deferens C. Tubuli recti D. Ductuli efferentes E. Seminal vesicle 15. Identify the cells indicated by the arrow: A. Mesangial cells B. Visceral epithelial cells C. Macula densa cells D. Parietal epithelial cells E. Juxtaglomerular cells 16. Identify this cell: A. Primary spermatocyte B. Leydig cell C. Spermatid D. Sertoli cell E. Spermatogonium 17. This structure is a: A. Primordial follicle B. Primary follicle C. Secondary follicle D. Corpus fibrosum E. Corpus atreticum 18. This electron micrograph shows each of the following EXCEPT : A. Podocyte foot processes B. Glomerular basement membrane C. Parietal epithelial cell cytoplasm D. Capillary lumen E. Endothelial cell fenestrations - 11 - HISTOLOGY PRACTICAL EXAM III ANSWER KEYS 1. B 2. D 3. C 4. B 5. B 6. A 7. A 8. D 9. D 10. B 11. D 12. A 13. D 14. D 15. D 16. C 17. A 18. C HISTOLOGY WRITTEN EXAM III - VERSION 1 - ANSWER KEYS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 C B C D D C B A B E C B A C B D E E D B 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 C E A E E C B C B E D A B E D D C B A 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 - 12 - E E E D E B C A A D B B C A B B A A B C