University of Toronto at Mississauga PSY295F Fall 2004 Introduction to Neuropsychology T3-6 Room 2072 Instructor: Vedran Lovic, M.A. Tel. 905-828-5297 vedran@psych.utoronto.ca Office: 1015 Office Hours: T2-3 or by apptmt. Assistants: Pearl Behl pearl.behl@sw.ca Office: PUMP room Office Hours: by apptmt. Christine Burton christine@psych.utoronto.ca Office: CCIT 4027 Office Hours: by apptmt. Erica Thule erica@psych.utoronto.ca Office: CCIT 4027 Office Hours: by apptmt. About me: I am a naturalized Canadian, born in Bosnia-Herzegovina. I finished my bachelor of science and master of arts degrees at the University of Toronto and currently I am a Ph.D. student working in Dr. Alison Fleming’s behavioural neuroscience laboratory. My research is concerned with the role of early life environment in the development of behavioral flexibility and impulsiveness and how alterations of these behaviors are mediated by the dopamine and serotonin systems. Synopsis: In this course we will examine the relationship between brain, behaviour and cognitive abilities. Initial lectures will be a general introduction to neuroanatomy, cortical organization and methods used by neuropsychologists. This will be followed by lectures focusing on specific brain functions, such as memory and language functions. Throughout the course we will learn about this relationship between brain and behaviour from brain injury cases (e.g., head injuries, strokes, tumors etc.) as well as from research done on intact individuals. Objectives: At the end of the course you will have an understanding of how the brain is organized and how it accomplishes some of the behaviors and cognitive functions. As mentioned above, the course will cover some popular topics such as amnesia and “frontal” syndromes and therefore the course might be of interest to a wide spectrum of students. However, students interested in pursuing neuropsychology or neurology studies will find the course particularly useful. By completing this course you will fulfill the second year “Physiological Psychology” requirement. This course can be used as one of the prerequisites for third and fourth year physiological psychology courses (e.g., Hormones and Behavior, Neural Plasticity, Cognitive Neurology, Motivational Systems, Biological Bases of Abnormal Behavior, Psychobiology Laboratory etc.). Course Format: Classes will consist of lectures and videos demonstrating impairments in cognitive abilities outlined in lectures. Lectures will be based on textbook and extra material, hence students are strongly encouraged to attend lectures. Lectures will be done using powerpoint slide presentation, which will be available on the course web site after each lecture. Textbooks: Kolb, B. & Whishaw, I.Q. (2003). Fundamentals of Human Neuropsychology, 5th edition. New York: W.H. Freeman & Co. (Approximate price: $ 110.00) Sacks, O. (1998). The Man Who Mistook His Wife for a Hat and Other Clinical Tales. New York: Touchstone. (Approximate price: $ 21.00) University of Toronto at Mississauga PSY295F Fall 2004 Introduction to Neuropsychology T3-6 Room 2072 Readings: Students are encouraged to read the assigned readings before each lecture as this will facilitate and extend their knowledge acquired in class. Kolb & Whishaw textbook has been around for more than two decades and it is considered to be the best textbook in the field. Readings from Kolb & Whishaw are detailed and will require you to remember and integrate information. You should pay close, but not exclusive, attention to the material that overlaps with lecture material. Readings from Sacks are there to illustrate clinical conditions relevant to topics covered in lectures and Kolb & Whishaw. Try to extract the most important information from Sacks readings. Web Page: www.erin.utoronto.ca/~w3psy295/psy295.htm Grading: Term Tests (2 x 20%) Term Paper Final Exam Tests: Term tests will be based on the material from the textbook, lectures and videos. The tests will consist of multiple-choice questions (~50%; based on Kolb & Whishaw), matching questions (based on Kolb and Whishaw and lectures) shorter and longer questions as well as a diagram requiring you to label brain parts (based on lectures, videos and textbooks). The shorter and longer questions will require students to recite information but also integrate knowledge analytically. Please see question examples on the web. 40% 25% 35% Prerequisites: PSY 100. It is your responsibility to ensure that you have met all prerequisites listed in the UTM Calendar for this course. If you lack any prerequisites for this course, the Department may cancel your registration at anytime. Further information about academic regulations, course withdrawal dates and credits can be found in the University of Toronto at Mississauga Calendar. You are encouraged to read this material. If you run into trouble and need information about studying, preparing for exams, note taking or time management, free workshops and advice are available from the Academic Skills Centre. Make-ups: For this particular course, there will be NO make-up tests. If you miss one of the term tests without a legitimate excuse, you will receive a mark of zero for that term test. If you do have a legitimate excuse (e.g., doctor’s note; please see Calendar), your final exam will be worth 65%. Departmental Policy on Missed Tests and Extensions: All requests for makeup tests must be completed on a special form obtained from the Psychology Office and submitted to the Undergraduate Assistant within one week (Room 2037B). If you submit medical documentation make sure it contains the statement "This student was unable to write the test (or submit term work by the last day of classes, if applicable) on (date) for medical reasons". You are advised to see your physician within one day of the missed test. Many physicians will not provide documentation retroactively. www.utm.utoronto.ca/~w3psy/index_files/MissedTest.htm University of Toronto at Mississauga PSY295F Fall 2004 Introduction to Neuropsychology T3-6 Room 2072 Schedule of Lectures and Readings Date Topic Kolb & Whishaw Sacks Sep 14 The Development of Neuropsychology 1 Sep 21 Neuroanatomy and Cortical Organization 3 & 10 3&6 Sep 28 Methods in Neuropsychology 7 & 26 17 Oct 5 Test 1 Oct 12 Vision and Agnosias 13 1 Oct 19 Attention and Neglect 14 4, 5 & 8 Oct 26 Language and Aphasias 19 9 Nov 2 Memory and Amnesias 18 2 & 19 Nov 9 Test 2 Nov 16 Executive Functions and Emotion 16 & 20 11 & 13 Nov 23 Hemispheric Specialization (Paper Due) 11 & 12 Nov 30 Psychiatric Disorders 27 10 & 14 Dec 7 Developmental Disorders and Review 24 24 University of Toronto at Mississauga PSY295F Fall 2004 Introduction to Neuropsychology T3-6 Room 2072 Term Paper The purpose of the term paper is to develop your writing skills by organizing, synthesizing and evaluating a body of research, while gaining an in-depth knowledge about a particular topic in the field of neuropsychology. The paper should include a review of the literature, critical evaluation of the evidence presented, as well as a set of conclusions. The paper will be graded based on its content as well as style (organization, grammar, spelling and following APA guidelines). Select a topic from the list of topics that is of interest to you. Your paper should be written in the APA format and should include the following sections: abstract (summary of your paper, approximately 150 words), the text (with an introduction, body and a conclusion, 1000-1250 words; Times New Roman, 12pt font – 4-5 pages), and the references (you should have at least 5 primary references – research studies, not review papers). The paper is due on Nov. 23, 2004, at the beginning of class – any papers received after 3:15 will be considered late. For each day the paper is late (including weekends) 4 marks will be deducted. The paper should be generally organized in the following manner: Title page Abstract (summary of your paper) Introduction with an overview and description of a syndrome/cognitive domain (3/4 page) Literature review (including a minimum of 5 primary references)(3-4pages) Summary of main points, conclusions and future research (3/4 page) References in APA format After selecting a topic you should do some preliminary research on the topic. Use Psych Lit, PsychInfo, or Pub Med (http://www4.ncbi.nlm.nih.gov/PubMed/) to find primary references (data-based journal articles that describe the collection and analyses of data). In addition to these primary references, you may include additional primary references, book chapters or review articles summarizing primary research. Do not use textbooks or popular magazines (e.g., Psychology Today, Times etc.). Below is a list of some of the journals that you are likely to encounter in your search: Brain Brain and Cognition Brain Injury Epilepsy & Behavior Hippocampus Journal of Clinical and Experimental Neuropsychology Journal of Neurosurgery Neurology Neuropsychologia Neuropsychology Plagiarism: Make sure you understand the University’s guidelines on plagiarism. See the 1998 revision of “How Not to Plagiarize” at www.utoronto.ca/writing/plagsep.html. Writing: For information on writing a paper in APA style consult: Publication Manual of the American Psychological Association (5th ed.). (2001). Washington, DC: American Psychological Association. (BF76.7 A46 2001) Also see: http://www.utoronto.ca/writing/ University of Toronto at Mississauga PSY295F Fall 2004 Introduction to Neuropsychology T3-6 Room 2072 Topics Multiple memory systems in the brain Hippocampus and memory Contralateral neglect Prosopagnosia and object agnosia – brain mechanisms for face and object perception Blindsight Implicit memory in amnesia Cortical and subcortical mechanisms of attention Broca’s aphasia Wernicke’s aphasia Cognitive differences between males and females and mechanisms of these differences Reading disorders resulting from brain damage Communication deficits resulting from right brain injury Brain mechanisms of cognitive and behavioural flexibility Executive function deficits following frontal lobe damage Korsakoff’s Syndrome Balint’s Syndrome Emotional changes following brain injury Theory of mind in the brain Brain mechanisms of humor Brain mechanisms of self-awareness Consciousness and the cortex Cognitive deficits in Parkinson’s Disease Memory deficits in Alzheimer’s Disease Long-term effects of mild brain injury Antisocial behavior following brain injury Memory deficits associated with epilepsy Utilization behavior following brain injury Brain mechanisms of working memory Frontotemporal lobar dementia Memory deficits in schizophrenia Attentional deficits in schizophrenia Neuropsychology of normal aging Synesthesia Asterognosis Right frontal lobe and self-awarenes NOTE: PLEASE SUBMIT PAPER COPIES OF YOUR TERM PAPER. DO NOT E-MAIL YOUR TERM PAPER TO US. Make sure you keep a copy of your term paper on file. Also, keep all the journal articles that you use for your paper as you might be asked to hand those in.