Unit details [CBA]
Biochemistry 2 (Medicine)
Enrolment code: CBA200
Offered: Hbt: (fy) ie sem 1 & 2,
Special note: restricted to students enrolled in Medicine; taught by Discipline of Biochemistry
Unit description:
Provides medical students an understanding of: (a) structure and function of important
biological macromolecules, such as nucleic acids and proteins; (b) structure, function and
metabolism of amino acids, carbohydrates and lipids; (c) the integration and control of
metabolism, by hormonal and other means; (d) nutrition – roles of macro- and
micro-nutrients in health and disease, dietary guidelines, food composition; (e) basic
human genetics; (f) human molecular biology in health and disease; (g) metabolic and
genetic basis of disease states. Relevance to human health and disease is highlighted.
Staff: Dr DR Woodward (Coordinator), Dr SM Richards, Dr AK West, Dr AF Holloway
Unit weight: 20%
Teaching pattern: 59 hrs lectures; 13 hrs tutorials
Prereq: 1st year Medicine
Coreq: CHG210
Assess: 2-hr written paper at end of sem 1 (45%); 2-hr written paper at end of sem 2 (35%);
assessments during sem (20%)
Required: either
Meisenberg G & Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
Recommend: Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to
Molecular Biology of the Cell, Garland, NY, 1998, ISBN 0815329717
Garrow JS, James WPT & Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000, ISBN 0443056277
Marks DB, Marks AD & Smith CM, Basic Medical Biochemistry: A Clinical Approach,
Williams & Wilkins, Baltimore, 1996, ISBN 0683230107
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Mueller RF & Young ID, Emery’s Elements of Medical Genetics, 11th edn, Churchill
Livingstone, Edin, 2000, ISBN 044307125X
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –1
Unit details [CBA]
Nelson DL & Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000, ISBN
1572599316
Courses: [M3J] [M3B] [M4B]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry (Pharmacy)
Enrolment code: CBA220
Offered: Hbt: (fy) ie sem 1 & 2,
Unit description:
Gives pharmacy students an understanding of the following core areas of biochemistry
and molecular biology: (a) structure and function of important biological macromolecules,
such as nucleic acids and proteins; (b) structure, function and metabolism of amino acids,
carbohydrates and lipids; (c) the integration and control of metabolism, by hormonal and
other means; (d) nutrition – role of macro- and micro-nutrients in health and disease, food
composition, dietary guidelines; (e) basic human genetics; (f) human molecular biology in
health and disease; (g) metabolic and genetic basis of disease states. Relevance to human
health and disease is highlighted.
Staff: Dr AF Holloway, Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 2–3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prereq: KRA160, CHG101
Assess: 2-hr written paper at end of sem 1 (45%), 2-hr written paper at end of sem 2 (35%),
assessments during sem (20%)
Required: either
Meisenberg G & Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
Recommend: Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to
Molecular Biology of the Cell, Garland, NY, 1998, ISBN 0815329717
Garrow JS, James WPT & Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000, ISBN 0443056277
Marks DB, Marks AD & Smith CM, Basic Medical Biochemistry: A Clinical Approach,
Williams & Wilkins, Baltimore, 1996, ISBN 0683230107
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –2
Unit details [CBA]
Mueller RF & Young ID, Emery’s Elements of Medical Genetics, 11th edn, Churchill
Livingstone, Edin, 2000, ISBN 044307125X
Nelson DL & Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000, ISBN
1572599316
Courses: [M3F]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry (Agriculture)
Enrolment code: CBA235
Offered: Hbt: sem 1,
Special note: restricted to Agricultural Science students; taught by Discipline of Biochemistry
Unit description:
Gives agricultural science students an introduction to: (a) structure and function of
important biological macromolecules, such as nucleic acids and proteins; (b) structure,
function and metabolism of amino acids, carbohydrates and lipids; (c) the integration and
control of metabolism, by hormonal and other means; (d) molecular biology; (e) nutrition.
Staff: Dr SM Richards, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prereq: KRA120 and KPZ162 and KZA160; students who do not have these prereqs should
consult unit coordinator
M.excl: may not be included in BAgSc with CBA230
Assess: 3-hr written paper at end of sem 1
Required: Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf,
2001, ISBN 0198700458
Recommend: Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to
Molecular Biology of the Cell, Garland, NY, 1998, ISBN 0815329717
Campbell MK, Biochemistry, 3rd edn, Saunders, Philadelphia, 1999, ISBN 0030244269
Hanes BD & Hooper NM, Instant Notes Biochemistry, 2nd edn, Bios, Oxf, 2000, ISBN
1859961428
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Nelson DL & Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000, ISBN
1572599316
Courses: [S3A]
Faculty website: <www.healthsci.utas.edu.au>
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –3
Unit details [CBA]
Biochemistry: Metabolism & Nutrition
Enrolment code: CBA260
Offered: Hbt: sem 1
Special note: restricted to students enrolled in Science
Unit description:
Provides students with a broad introduction to metabolic and nutritional aspects of
biochemistry. Major topics include structure, function and metabolism of amino acids,
carbohydrates and lipids; the integration and control of metabolism, by hormonal and
other means; roles of selected nutrients in health and disease.
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZAI 51
and KPA150, as well as a first-year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff: Dr AF Holloway, Dr SM Richards, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 2–3x1hr lectures, 3hrs lab weekly; 1-hr tutorial fortnightly
Prereq: ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G). See note above.
M.excl: this unit may NOT be included in BSc with CBA250 or CBA211
Assess: 3-hr written end-of-sem paper (80%), practicals (10%), tests during sem (10%)
Required: either
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
or
Meisenberg G & Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommend: All of the above, plus
Campbell MYC, Biochemistry, 3rd edn, Saunders, Philadelphia, 1999, ISBN: 0030244269
Garrow JS, James WPT & Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000 ISBN: 0443056277
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN: 0716720094
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –4
Unit details [CBA]
Wahlqvist ML, Food and Nutrition: Australia Asia and the Pacific, Allen & Unwin, St
Leonards, 1997, ISBN: 1864482206
Nelson DL & Cox IM, Lehninger Principles of Biochemistry, 3nd edn, Worth, NY, 2000, ISBN:
1572599316
Courses: [S3G] [S3Gc1] [S3Gc2]
Faculty website: <www.healthsci.utas.edu.au>
Molecular Biology in Health & Disease
Enrolment code: CBA265
Offered: Hbt: sem 2
Special note: restricted to students enrolled in Science
Unit description:
Provides students with a broad introduction to molecular biology. The focus is primarily
on humans and other mammals, but most of the matters discussed apply to a much
broader range of species. Major topics include protein structure and function; DNA
structure, replication and transcription; protein synthesis; molecular biology of cancer;
genetics of human disease; DNA technology and its applications.
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZA151
and KPA150, as well as a first1year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff: Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 2x1-hr lectures, 3 hrs lab weekly; 1-hr tutorial fortnightly
Prereq: ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G).
M.excl: This unit may not be included in BSc with CBA250 or CBA211
Assess: 3-hr written end-of-sem paper (90%), practicals (10%)
Required: either
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
or
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –5
Unit details [CBA]
Meisenberg G & Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommend: All of the above, plus
Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to Molecular Biology
of the Cell, Garland, NY, 1998, ISBN 0815329717
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Mueller RF & Young ID, Emery’s Elements of Medical Genetics, 11end, Churchill Livingstone,
Edin, 2000, ISBN 044307125X
Nelson DL & Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000, ISBN
1572599316
Courses: [S3G] [S3Gc1] [S3Gc2]
Faculty website: <www.healthsci.utas.edu.au>
Molecular Biochemistry: Techniques and Theory
Enrolment code: CBA327
Offered: Hbt: (fy) ie sem 1 & 2,
Unit description:
Provides students with (/i) an understanding and application of contemporary techniques
in protein biochemistry and molecular biology and (ii) an understanding of contemporary
developments in the areas of biochemistry relating to hormones, signal transduction and
molecular biology, particularly advanced related to geneomics, transgenesis, cloning and
the Human Genome Project Lectures cover: techniques in protein biochemistry and
molecular biology including isolation of organelles and membrane proteins; predictive
and actual structure of membrane proteins; measurement of membrane transport
processes; relationship of structure and function of membrane proteins; isolation and
purification of proteins and enzymes; determination of kinetic constants of enzymes;
isolation of nucleic acids (DNA and RNA) from cells; in vitro manipulation of nucleic
acids, including PCR, site-directed mutagenesis, sequencing; cDNA libraries; detection of
sequences of defined composition and reintroduction of genes into bacterial and
eukaryotic cells; transformation, transfection, transgenic animals, microarrays,
bioninformatics, control of gene expression; mammalian cloning by nuclear transfer;
hormonal control systems; adrenergic control systems; insulin and insulin-like growth
factors; receptors; phosphoinositol turnover and control of intracellular calcium; protein
kinases; phosphoprotein phosphatases; covalent modification. Practicals emphasise
‘hands-on’ experience with contemporary biochemical techniques. The unit features a
10-week research project in the second semester.
Staff: Prof MG Clark, Dr AK West
Unit weight: 50%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
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University of Tasmania unit details for 2003 academic year
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Unit details [CBA]
Prereq: CBA260 and CBA265
Assess: 2-hr written exam in June, 3-hr written exam in Nov, with 30% of final mark from
practical assignments and projects
Required: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, ISBN 0896035018
Recommend: Alberts B, Johnson A, Lewis J, RaffM, Roberts K & Walter P, Molectular Biology
of the Cell, 4th edn, Garland NY, 2002, ISBN 0815340729
other appropriate material will be indicated during the year.
Courses: [S3G]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry for Biotechnology
Enrolment code: CBA330
Offered: Hbt: sem 1
Unit description:
Provides students with an understanding and application of contemporary techniques in
protein biochemistry and molecular biology central to biotechnology, eg, genomics,
transgenesis, cloning and the Human Genome project. Lectures cover: techniques in
protein biochemistry and molecular biology including isolation of organelles and
membrane proteins; predictive and actual structure of membrane proteins; measurement
of membrane transport processes; relationship of structure and function of membrane
proteins; isolation and purification of proteins and enzymes; determination of kinetic
constants of enzymes; isolation of nucleic acids (DNA and RNA) from cells; in vitro
manipulation of nucleic acids, including PCR, site-directed mutagenesis, sequencing;
cDNA libraries; detection of sequences of defined composition and reintroduction of genes
into bacterial and eukaryotic cells; transformation, transfection; microarrays,
bioinformatics. Practicals emphasise ‘hands-on’ experience with contemporary
biochemical techniques.
Staff: Prof MG Clark, Dr AF Holloway, Dr AK West
Unit weight: 25%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prereq: CBA260 and CBA265
M.excl: CBA327
Assess: 2-hr written exam in June (70%), practicals (30%)
Required: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, 1998, ISBN 0896035018
________________________________________
University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –7
Unit details [CBA]
Recommend: Alberts B, Johnson A, Lewis J, Raff M, Roberts K & Walter P, Molecular Biology
of the Cell, 4th edn, Garland NY, 2002, ISBN 0815340729
Other appropriate material will be indicated during the year.
Courses: [S3V]
Faculty website: <www.healthsci.utas.edu.au>
Advanced Biochemistry for Biotechnology
Enrolment code: CBA335
Offered: Hbt: sem 2
Unit description:
Provides students with in-depth coverage of selected topics relevant to biotechnology,
with a major emphasis on research laboratory experience. This unit is an excellent
preparation for students wishing to undertake a biomedically-oriented Honours degree.
Lectures cover: transgenic animals; control of gene expression; mammalian cloning by
nuclear transfer, human gene therapy, stem cell technology; hormonal control systems;
adrenergic control systems; insulin and insulin-like growth factors; receptors;
phosphoinositol turnover and control of intracellular calcium; protein kinases;
phosphoprotein phosphatases; covalent modification. The practical component comprises
a major research project which may be selected from any of the research themes in the
Discipline of Biochemistry.
Staff: MG Clark, Dr AF Holloway, Dr AK West
Unit weight: 25%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prereq: CBA260 and CBA265 and CBA330
M.excl: CBA327
Required: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, 1998, ISBN 0896035018
Recommend: Alberts B, Johnson A, Lewis J, Raff M, Roberts K & Walter P, Molecular Biology
of the Cell, 4th edn, Garland NY, 2002, ISBN 0815340729
Other appropriate material will be indicated during the year.
Courses: [S3V]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry 4 (BSc Honours)
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University of Tasmania unit details for 2003 academic year
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Unit details [CBA]
Enrolment code: CBA410
Offered: Hbt: (fy) ie sem 1 & 2,
Special note: for Science students only
Unit description:
Aims: (a) to provide students with the opportunity to plan, execute, interpret and analyse
purposeful experiments, appropriate to their research project, and to communicate their
results; and to investigate and present on two areas, unrelated to their own research topic,
but representing important contemporary biochemical research in order to demonstrate
their skills in providing a condensed account of these areas of research and in
communicating their essential features in written and oral form; and (b) to provide a
year’s training in research, in order to give successful students a competitive edge in
seeking employment in biochemical research laboratories. The unit tests abilities which
were largely ignored in the earlier years. Students who excel in this Honours year are well
organised, plan carefully, are intensely motivated, are innovative thinkers, and express
their ideas and findings clearly.
Staff: Prof MG Clark, Dr AK West, Dr DR Woodward, Dr AF Holloway, Dr SM Richards
(Coordinator)
Unit weight: 100%
Prereq: BSc including CBA327 or equiv
Assess: the year’s performance is assessed from the research topic (thesis, 60%; project
seminar, 10%), and 2 assignments (10% for the essay and 10% for the reading topic
seminar presentation), supervisor’s assessment (10%). There are no written exams or
lectures, but students are expected to attend Discipline of Biochemistry seminars and those
of their own research group
Courses: [S4E]
Faculty website: <www.healthsci.utas.edu.au>
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University of Tasmania unit details for 2003 academic year
March 6, 2016, 18:23 PM, page –9