Chapter 24: Fluid & Electrolytes, Page 1 of 15 ALTERATION IN FLUID AND ELECTROLYTE STATUS Many questions based on dehydration. MAINTENANCE REQUIREMENT/FLUID REQUIREMENT Maintenance fluid is the amount of fluid the body need to replace normal daily losses - in kids these losses occur from the respiratory tract, UO, skin, GI tract. A well child usually drinks more than maintenance requirements; if they take in significantly less than maintenance they will become dehydrated. The requirement for maintenance varies depending on the weight of the child. Infants need more fluid per kg than the older child. DAILY FLUID REQUIREMENT (24 HOUR PERIOD) 100ml/kg for 1st 10kg of weight + 50ml/kg for the next 10kg + 20ml for every kg over 20kg SAMPLE FLUID CALCULATION 10kg child 10 kg x 100 ml/kg = 1000 ml/ per day 15kg child 10 kg x 100 ml/kg + 5kg x 50 ml/kg =1250 ml /per day 25kg child 10 kg x 100 ml/kg + 10 kg x 50 ml/kg + 5 kg x 10 ml/kg =1600 ml/ per day PEDIATRIC ELECTROLYTE VALUES Potassium (K+) 3.5 – 5.0 Sodium (Na+) 135 – 145 BUN 5 – 25 Creatinine 0.5 – 1.5 Calcium (Ca) 8.4 – 11.0 Chloride (CL-) 98 – 107 ELECTROLYTES Electrolytes account for approximately 95% of the solute molecules in body water. Sodium Na+ is the predominant extracellular cation. Potassium K+ is the predominant intracellular cation. DEVELOPMENTAL AND BIOLOGICAL VARIANCES Infants younger than 6 weeks do not produce tears. In an infant a sunken anterior fontanel may indicate dehydration. Infants are dependant on others to meet their fluid needs. Infants have limited ability to dilute and concentrate urine. The smaller the child, the greater the proportion of body water to weight and proportion of extracellular fluid to intracellular fluid. Infants have a larger proportional surface are of the GI tract than adults. Chapter 24: Fluid & Electrolytes, Page 2 of 15 Infants have a greater body surface area and higher metabolic rate than adults. INCREASED FLUID NEEDS DECREASED FLUID NEEDS Fever Congestive Heart Failure Vomiting and Diarrhea Mechanical Ventilation – due to moisturized O2 and lack High-output renal failure of activity Diabetes insipidus Renal failure Burns Head trauma/meningitis Shock Tachypnea GENERAL APPEARANCE How does the child look? o Skin: Temperature Skin and mucous membranes Turgor, tenting, dough-like feel Sunken eyeballs; no tears Pale, ashen, cyanotic nail beds or mucous membranes. Delayed capillary refill > 3 seconds Know the difference between mild, moderate, and severe dehydration. LOSS OF SKIN ELASTICITY Due to dehydration. In moderate dehydration the skin may have a doughy texture and appearance. In severe dehydration the more typical “tenting” of skin is observed. CARDIOVASCULAR ALTERATIONS IN FLUID SHIFTS Pulse rate change: o Note rate and quality: tachycardia may be subtle—pulse is often the first VS to change o Rapid, weak, or thready o Bounding or arrhythmias due to K+ deficit Blood Pressure o Note increase or decrease o Will be last to change – child is in big trouble at this point Respiratory Alterations in fluid shifts Change in rate or quality Hypovolemia o Tachypnea o Apnea o Deep shallow respirations Fluid overload o Moist breath sounds o Cough HGB AND HCT ALTERATIONS IN FLUID SHIFTS Measures hemoglobin, the main component of erythrocytes, which is the vehicle for transporting oxygen. Chapter 24: Fluid & Electrolytes, Page 3 of 15 Hgb and hct will be increased in extracellular fluid volume loss. Hgb and hct will be decreased in extracellular fluid volume excess. HYPERKALEMIA Potassium level above 5.5 mEq / L Significant dysrhythmias and cardiac arrest may result when potassium levels rise above 6.0 mEq/L Clinical manifestations: Nausea Irregular heart rate (only on monitor) Pulse slow / irregular Causes of: Acute or chronic renal failure/glomerulonephritis ↓ circulatory volume/volume depletion Rapid infusion of K+ Blood transfusion (older blood products) ↑ cell breakdown Rhabdomyolisis-tissue and muscle breakdown, tumor lysis, starvation Medications: NSAIDs, ace inhibitors, β blockers Metabolic acidosis Hypoglycemia HYPOKALEMIA Potassium level below 3.5 mEq / L – child should be on a cardiac monitor. Before administering supplemental K+ make sure child is producing urine. A child on potassium wasting diuretics (furosemide) is at risk for hypokalemia. Clinical manifestations Neuromuscular: o diminished bowel sounds o truncal weakness o limb weakness, o lethargy o abdominal distention. CAUSES OF HYPOKALEMIA Metabolic Acidosis Vomiting / diarrhea Malnutrition / starvation Stress due to trauma from injury or surgery. Gastric suction / intestinal fistula Potassium wasting diuretics Ingestion of large amounts of ASA Chapter 24: Fluid & Electrolytes, Page 4 of 15 Dehydration Meds: Diuretics, aminoglycocides, β agonists, insulin, caffeine TREATMENT OF HYPOKALEMIA If patient is dehydrated: rehydrate with K+ containing fluid or ORT (pedialyte) o Mild-moderate hypokalemia (2.5-3.5) oral usually works o Severe (<2.5) - IV diluted, SLOWLY no faster than 1mg/kg over 4h. Can require repeated infusion to bring level up to acceptable range o Check Mg level, hypokalemia may not be correctable until Mg level is corrected. If you raise one you have to raise the other as well. o Treat underlying cause o Increase dietary K+ Extreme caution is needed with the administration of K+. There is no margin of error. K+ overdose = death Na+ Normal values: 135 to 145 mEq / L Sodium is the most abundant cation and chief base of the blood; helps conduct nerve impulses The primary function is to chemically maintain osmotic pressure and acid-base balance and to transmit nerve impulses. HYPONATREMIA Serum levels below 130 mEq / L Causes: net sodium loss or water excess Sodium loss resulting from gastrointestinal output, diuretics, excessive diaphoresis, and intake of large amounts of water with decreased sodium intake. Clinical manifestations: Excess fluid will shift into the cerebral compartment, which produces increased intracranial pressure: seizures, coma, respiratory arrest and brain damage. Hyponatremia is the most common cause of seizures. HYPERNATREMIA Serum level above146 mEq / L Causes: insufficient fluid intake or excessive fluid losses. Excessive salt intake or insufficient sodium excretion Altered thirst Increased insensible loss, increase in GI output, watery diarrhea, profuse vomiting) Excessive solute intake (incorrectly diluted formula) Kidney disease Diabetes insipidus Clinical manifestations: Increased irritability with stimulation or high-pitched cry. Chapter 24: Fluid & Electrolytes, Page 5 of 15 Lethargy Seizures Coma MEDICAL MANAGEMENT OF THE CHILD WITH HYPERNATREMIA Children with hypernatremia are almost always dehydrated. o Determine cause o Correct cause o Fluid resuscitation: Replace fluids with hypotonic fluid- SLOWLY over 48 hours Too rapid an attempt at correction will result in H2O shift in brain causing cerebral edema CLINICAL FEATURES OF DEHYDRATION Mild 5% Moderate 10% Severe >15% HR WNL Slightly ↑ Tachycardic, weak Systolic BP WNL WNL to orthostatic (>10mm/Hg change) Hypotensive UO ↓ Moderate ↓, ↑SG Markedly ↓, Anuria Mucus Membranes Slightly dry Very dry Parched Ant. fontanel WNL WNL to sunken Sunken Tears + ↓, eyes sunken Absent, eyes sunken Skin turgor WNL Decreased turgor Tenting Overall condition Well, alert Restless, irritable Lethargic, floppy Thirst WNL Drinks eagerly Unable to drink Skin perfusion WNL <2sec Slow 2-4sec, skin cool to touch Very delayed >4sec, skin cool, mottled, cyanotic ORAL REHYDRATION THERAPY (ORT) is a specific procedure intended to rehydrate the moderately dehydrated infant or toddler. Its advantages over parenteral therapy include fewer complications, lower cost, lower hospitalization rate, and minimizing the risk of hypernatremia or hyponatremia. Only for child with moderate dehydration – not severe dehydration. Pedialyte is the most commonly used ORT in the U.S. ORT Indications for use of ORT Children between 3 mos. and 5 years of age with acute diarrheal illness with or w/o vomiting Children with mild to moderate dehydration Patient is able to tolerate oral intake Normal bedside glucose Chapter 24: Fluid & Electrolytes, Page 6 of 15 Parental ability and willingness to comply with procedure. Shock Contraindications: Altered mental status Severe dehydration Parental limitations/ Unreliable home situation Excessive vomiting / Uncontrolled diarrhea Abdominal distention or absent bowel sounds Abnormal bedside glucose (Adjusted) Age 3 months or less Complicated medical history (premature, cardiac anomalies, AIDS, etc.) RE-HYDRATION THERAPY for mild to moderate dehydration Increase po fluids if diarrhea increases. Give po fluids slowly if vomiting. Stop ORT when hydration status is normal Start on BRAT diet o Bananas o Rice o Applesauce (whole apples NOT apple juice) o Toast TREATMENT OF MILD TO MODERATE DEHYDRATION ORT (oral re-hydration therapy) o 1-2 oz per pound divided into frequent feedings of: infant: 3-4 oz qh child: 1-2 oz qh o Non-carbonated soda, jell-o, fruit juices, ice pops. o Commercially prepared solutions are the best: Pedialyte PARENT TEACHING Call PNP/MD o If diarrhea or vomiting increases o No improvement seen in child’s hydration status. o Child appears worse. o Child will not take fluids. o NO URINE OUTPUT o If child is very irritable or any other change in neurologic function MODERATE TO SEVERE DEHYDRATION: IV Therapy is needed FLUID REPLACEMENT Isotonic fluids initially: o Normal Saline 0.9% Chapter 24: Fluid & Electrolytes, Page 7 of 15 o Followed by: Dextrose 5% in 0.45% NS Potassium is added only after child has voided. NURSING INTERVENTIONS Assess child’s hydration status Accurate intake and output (weigh diapers/sheets) 1g of wet diaper = 1mL Daily weights o most accurate way to monitor fluid levels Hourly monitoring of IV rate and site of infusion. o Increase fluids if increase in vomiting or diarrhea. o Decrease fluids when taking po fluids or signs of edema. A severely dehydrated child will need more than maintenance to replace lost fluids. 1½-2 times maintenance. Adding potassium to IV solution. Never add in cases of oliguria/anuria or if urine output is < 0.5 mg/kg/hour Never give IV push If adding K+ to IVF double check dosage/amount drawn up with another RN EVEN if this is NOT your institutions policy. There is no margin of error K+ overdose = DEATH FLUID OVERLOAD Occurs when child receives more IV fluids that needed for maintenance. In pre-existing conditions such as meningitis, head trauma, kidney shutdown, nephrotic syndrome, congestive heart failure, or pulmonary congestion. S/S FLUID OVERLOAD Tachypnea Dyspnea Cough Moist breath sounds Weight gain from edema Jugular vein distention IV THERAPY IN PEDIATRICS Use small bags of fluid (250mL/500mL) and buretrol to control fluid volume. Check IV solution against physician orders. Always use infusion pump so that the rate can be programmed and monitored. There are only (2) exceptions to not using an infusion pump in Peds: o Adolescent who is almost “adult” size (>120lbs) o Massive trauma with severe hypovolemia (in ER / PICU only) Mechanical pumps can fail, IV’s can “blow” , o IV bag, site, pump and rate must be checked hourly. DEHYDRATION Chapter 24: Fluid & Electrolytes, Page 8 of 15 The excessive loss of water from body tissues. It is a very common occurrence in the pediatric population whenever total fluid intake is less than total fluid output. Dehydration is classified by degree and type: DEGREE mild, moderate, or severe TYPE isotonic, hypertonic, or hypotonic The main causes of dehydration in the pediatric population are: Vomiting Diarrhea Increased BMR Decreased intake Diabetic ketoacidosis Severe burns Prolonged high fever Hyperventilation DEHYDRATION Physical assessment findings and lab values make the diagnosis of dehydration. Na+ can ↓ or stay WNL K+ can ↓ or stay WNL Cl- level ↓ ASSESSMENT OF THE CHILD WITH DEHYDRATION Clinical manifestations will depend on the degree of dehydration Thirst Fatigue Weight loss Dry MM ↓ or absent tear production Poor skin turgor ↑ capillary refill time Depressed fontanel (infant only) ↓ UO Tachycardia/ Tachypnea Lab Studies: UA with ↑ SG (>1.030) CBC: ↑ HCT, HgB, ↑ BUN Alterations in Na+, K+, ClTYPES OF DEHYDRATION Isotonic: Major fluid loss involves extracellular components and circulating blood volume Na+ WNL or ↓ Chapter 24: Fluid & Electrolytes, Page 9 of 15 K+ WNL or ↓ Hypertonic: Excessive loss of H2O (as compared to electrolytes) fluid shifts from intracellular to extracellular compartment. Child is at risk for neurological complications. Na+ ↓, K+ level varies, and Cl- ↑. Highest mortality is associated with this type Hypotonic: H2O shifts from extracellular to the intracellular compartments in an attempt to establish equilibrium, this shift further increase loss of extra cellular fluid and can lead to shock/ Na ↓, CL- ↓ and K+ varies. ISOTONIC DEHYDRATION Most common type in Pediatric Patients. The major fluid loss involves extracellular components and circulating vascular volume, this puts the child at risk for hypovolemic shock Causes: Hemorrhage GI losses: vomiting, NG drainage, diarrhea Fever; diaphoresis Burns Diuretics Third spacing of fluid Serum Na+ level usually stays normal (130-150) HYPOTONIC DEHYDRATION (water intoxication) More fluid is gained - causes an excess of fluid as compared to electrolytes electrolyte loss exceeds water loss. Water shifts from the extracellular to the intracellular compartments, which further increase the loss of extracellular fluid and commonly results in hypovolemic shock. Causes: Plain water enemas, plain water NG or bladder irrigation Overuse of hypotonic IVF or infused too rapidly Increased water intake (water gets replaced but not electrolytes - frequently happens with athletes) In young kids/infants occurs frequently when parents add too much water to commercial infant formula Serum Na+ decreases (less than 130) ISOTONIC IV FLUID Has approximately the same concentration (osmolatity) as that of extracellular fluid Chapter 24: Fluid & Electrolytes, Page 10 of 15 Are given to expand ECF volume Types of isotonic fluid Normal saline (0.9 NaCL) Lactated Ringers (LR) Dextrose 5% in water (D5W) HYPERTONIC IV FLUID Concentration (osmolatity) is higher than that of serum plasma Are given to increase the ECF volume and decrease cellular swelling Causes cells to shrink and contributes to ECF volume overload. Types of hypertonic fluid 5% dextrose in 0.9 % NaCl (D5NS) 10% dextrose in water (D10W) 0.3 NaCl 5% dextrose in water with 0.3 NaCL (D5W 0.3 NaCl) MILD-MODERATE DEHYDRATION Oral rehydration with Pedialyte (or its equivalent) in small quantities (1-2 oz/hr) Pedialyte promotes reabsorption of Na, H2O and reduces vomiting and diarrhea. o If child has diarrhea without dehydration, give Pedialyte + normal diet for age o If child is vomiting give very small amounts of Pedialyte (1-2 teaspoons) q5-10min as tolerated for 1 hour, increase as child's vomiting subsides. DO NOT give fruit juice, soda, sports drinks, chicken or beef broth. They are all very high in Na+ and glucose and will make the diarrhea and vomiting worse. MODERATE- SEVERE DEHYDRATION Restoration and maintenance of adequate hydration and electrolyte balance is the priority goal of the RN Initial fluid replacement consists of fluid boluses of an isotonic fluid at a rate of 20-30mL/kg (contraindicated in hypertonic dehydration due to the risk of water intoxication) Subsequent therapy is used to replace fluid & electrolyte losses. The fluid of choice is usually a saline solution with 5% dextrose (D5 ½ NS, D5 1/3 NS with or without K+). The selection of fluid is based on the probable cause of dehydration. NURSING PROCESS FOR THE CHILD WITH DEHYDRATION: Nursing Diagnoses: Fluid volume deficit Fluid volume excess Fluid volume imbalance Tissue perfusion, altered Urinary elimination, altered Chapter 24: Fluid & Electrolytes, Page 11 of 15 Altered tissue perfusion NURSING INTERVENTIONS FOR FLUID VOLUME DEFICIT Administer O2 as needed Monitor VS for hypotension/tachycardia/RR Continual assessment of LOC, muscle weakness Identify and correct underlying cause Identify medications that could be contributing to fluid loss, obtain orders to discontinue, decrease or change medication Weigh daily (same time/same scale) Careful evaluation and monitoring of I & O IV fluids as ordered Encourage po intake Monitor hydration status (MM/UO/skin turgor) Provide/encourage meticulous oral hygiene Monitor electrolytes (serum & urine) Monitor color & SG of urine NURSING INTERVENTIONS FOR FLUID VOLUME EXCESS Monitor breath sounds, SaO2 and RR Administer O2 as needed Monitor neurological status, ability to ambulate, weakness Identify and correct underlying cause Identify medications, IVF that may be contributing to fluid gains: obtain orders to discontinue or decrease dose/rate. Weigh daily (same time/same scale) Careful evaluation & monitoring of I&O Monitor for edema Administer diuretics as prescribed Restrict fluid and Na+ intake IV fluids as ordered, monitor IV site If child has diarrhea, meticulous care of perineum Maintenance of Foley catheter Parent teaching: Anti-diarrheal agents (lopermide) are not for use in children, their use can be fatal Reassurance and support Teach parents that acute diarrhea may produce temporary lactose intolerance. Avoid lactose for about 1 week after resolution. NURSING INTERVENTIONS FOR THE CHILD WITH DEHYDRATION: RESTORATION and maintenance of adequate hydration and electrolyte balance are the priority goals of the RN Initial replacement consists of fluid boluses of an isotonic fluid at a rate of 20-30ml/kg. Chapter 24: Fluid & Electrolytes, Page 12 of 15 Subsequent therapy is used to replace fluid and electrolyte losses. Usually D5 NS Correction of the condition that caused the dehydration Oral rehydration (Pedialyte) in small quantities o (1-2oz/hr), pedialye promotes reabsorption of Na + H20 (also reduces the amount and frequency of vomiting and diarrhea) Chapter 24: Fluid & Electrolytes, Page 13 of 15 DIARRHEA/ACUTE GASTROENTERITIS Diarrhea is the passage of frequent, watery, loose stools and is actually a symptom and not a disease. An increase in intestinal motility and rapid bowel emptying results in impaired absorption, this decrease in absorption causes inflammation of the bowel and a decrease in surface area for absorption. Diarrhea can be acute, chronic, inflammatory, viral or bacterial in nature. Electrolytes effected: Na+, K+, CL It can affect any part of the GI tract. Diarrhea accompanies many childhood diseases including respiratory infections and GI disorders. The younger the child the more severe and the faster the diarrhea will cause electrolyte imbalances. In young children untreated diarrhea can lead to hypovolemic shock and death. Diarrhea is the leading cause of death in children in the world. DIARRHEA/ACUTE GASTROENTERITIS Etiology/Pathophysiology: It can have many different causes; the specific etiology is not always identified. Bacterial infection (e.coli/salmonella/shigella) Viral infection (rotovirus/adenovirisu) Parasitic infection Fungal over growth Food sensitivity Food intolerance Lactose intolerance Introduction of new foods Stress, anxiety, fatigue Overeating Medications Surgical intervention (SBS) NURSING PROCESS IN THE CARE OF THE CHILD WITH DIARRHEA Assessment Amount, color, consistency and time of stools Strict I & O Daily weights Child's activity level Abdominal cramping, fever Skin integrity Lab: electrolytes with special attention to Na+, K+, CL Diagnostic test: ova & parasites, rotovirus, bacteria, salmonella, shigella, giardia Nursing Interventions Based on the cause of the diarrhea Rehydration first then Usually a BRAT diet is prescribed by provider. Chapter 24: Fluid & Electrolytes, Page 14 of 15 PREVENT dehydration, maintain electrolyte balance DIARRHEA Diarrhea without dehydration = Pedialyte + regular diet NO fruit juices, sport drinks, chicken or beef broth (Na & gluc) Advance to BRAT Diet as tolerated (bananas, rice. apples ,tea or toast) BRAT diet bananas (fresh or baby food) rice (white, plain no salt or butter) apples (not apple juice or sauce) Tea or toast (no butter or jelly) Advance to BRAT diet when acute diarrhea has subsided and rehydration is achieved. VOMITING The forceful ejection of gastric contents through the mouth, it is a well defined complex and coordinated process that is under the control of the CNS. Etiology/Pathophysiology: VERY common in children and is usually self-limiting. Can be associated with infectious process, ICP, toxin ingestion, food intolerance or allergy, obstruction in the GI tract, metabolic disorders or psychogenic problem. Requires NO treatment unless there are complications (dehydration/electrolyte imbalance/malnutrition/aspiration). NURSING ASSESSMENT: VOMITING The child’s age, pattern of vomiting and duration of symptoms help determine the cause/etiology Green bilious vomiting - think bowel obstruction Curdled stomach contents, mucous or fatty foods that are vomited several hours after eating suggest poor gastric emptying time. Vomitus that looks like coffee grounds is associated with bleeding NURSING PROCESS IN THE CARE OF THE CHILD WHO IS VOMITING Assessment: Note /document color, consistency, time Daily weights Strict I & O Activity level Abdominal cramping Fever Lab and dx tests (x-ray’s, sono, endoscopy, electrolytes, bun) Nursing Diagnosis: Fluid volume deficit Fluid volume imbalance Chapter 24: Fluid & Electrolytes, Page 15 of 15 Alteration in nutrition: less than body requirements Aspiration: risk for Electrolyte imbalance Nursing Intervention: Based on the cause of the vomiting very small amts of Pedialyte (1-2 teaspoons) q1-5 min as tolerated x 1hr, advance as child tolerates NO fruit juices, sport drinks, chicken or beef broth (Na & gluc) Prevention of electrolyte imbalance, dehydration and aspiration are the priority of all nursing interventions SYMPTOMS ASSOCIATED WITH VOMITING Fever and diarrhea Infection Constipation Obstruction Localized abdominal pain o Appendicitis o Pancreatitis o Peptic ulcer Headache/change in LOC o CNS disorder o Vomiting without nausea = Brain tumor Forceful or projectile o Pyloric stenosis