PHYSIOLOGY – METABOLISM
1.
A.
B.
C.
D.
E.
Basal metabolic rate of the average human is:
500 kcal/day
1000 kcal/day
1500 kcal/day
2000 kcal/day
2500 kcal/day
2.
A.
B.
C.
D.
E.
Metabolic rate can be affected by:
Thyroid hormone
Catecholamines
Body temperature
Food ingested
All of the above
3.
A.
B.
C.
D.
E.
Which of the following is FALSE?
Basal metabolic rate is lower in female than male
Depressed patient has lower basal metabolic rate
Children have smaller relative basal metabolic rate
Basal metabolic rate increases 14% for each celcius degree of fever
Basal caloric requirement of the average adult is 2000 kcal/day.
4.
A.
B.
C.
D.
E.
Which of the following regarding ATP is TRUE?
Hydrolysis of 1 mole of ATP releases 10-12 kcal.
Oxidative phosphorylation takes place in the cytoplasm
Rate of oxidative phosphorylation is only limited by the availability of oxygen.
All of the above
None of the above
5.
A.
B.
C.
D.
E.
Which of the following regarding carbohydrate metabolism is INCORRECT?
Glucokinase is only present in liver
Both hexokinase & glucokinase are stimulated by insulin
Glycolysis is the breakdown of glucose to pyruvate & lactate
Most abundant stores of glycogen is in muscle & liver
None of the above
6. Which of the following is TRUE?
A. Adrenaline stimulates phosphorylase, leading to increased blood glucose & lactate
B. Glucagon causes hyperglycemia without increased blood lactate
C. Glucose-6-phosphatase is only found in the liver & muscle
D. All of the above
E. None of the above
PHYSIOLOGY – METABOLISM - MCQ
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7.
A.
B.
C.
D.
E.
Which of the following regarding glucose is INCORRECT?
Renal threshold for glucose is reached when venous glucose level reaches 180mg/dL.
Normal fasting glucose is 3.9-6.1 mmol/dL
Glycosuria only occurs in uncontrolled diabetes mellitus
Maximal glucose absorption from the intestine occurs at 120g/hr.
All of the above
8.
A.
B.
C.
D.
E.
During exercise:
glycogenolysis in muscle & liver
 plasma insulin
 plasma glucagon
 plasma adrenaline
All of the above
9.
A.
B.
C.
D.
E.
Which of the following is TRUE?
Brain utilize 70% of glucose in the body at rest
Red cells uses 20-30% of glucose in the body at rest
5% of ingested glucose is converted to hepatic glycogen
Resting muscle uses fatty acid as substrate for metabolism
All of the above
10. Which of the following regarding protein turnover is FALSE?
A. Turnover rate of endogenous protein is 80-100mg/day.
B. Highest turnover rate of protein occurs in muscle
C. Most filtered amino acids in kidney are reabsorped.
D. All of the above
E. None of the above
11. Which of the following is glucogenic amino acid?
A. Leucine
B. Isoleucine
C. Phenylalanine
D. Alanine
E. Tyrosine
12. Increased uric acid level does NOT occur in:
A. AMI
B. Pneumonia
C. Leukaemia
D. Thiazide diuretics
E. Renal disease
PHYSIOLOGY – METABOLISM - MCQ
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13. Negative nitrogen balance occurs in:
A. Immobilization
B. Starvation
C. corticosteroid
D. insulin
E. All of the above
14. Excretion of the following substance does NOT reduce in starvation:
A. Urea
B. Uric acid
C. Creatinine
D. Etheral sulfate
E. All of the above
15. Prolonged starvation in non-diabetic man is NOT characterized by:
A. Ketosis
B. Hypoglycemia
C. Glycogen depletion
D. Protein catabolism
E. None of the above
16. Which of the following is FALSE?
A. Saturated fats does not possess any double bonds
B. Desaturated fats are dehydrogenated fat with double bonds
C.  deoxidation of fatty acid is the only source of acetyl coA
D. Long chain fatty acids must be bound to carnitine to enter mitochondria for 
oxidation.
E. Catabolism of 1 mole of 6-carbon fatty acid yields 44 moles ATP.
17. Ketone bodies are found in:
A. Liver
B. Kidney
C. Fat cells
D. Muscle
E. All of the above
18. Which of the following ketone bodies is NOT anions of acids
A. Acetoacetate
B.  hydroxybutyrate
C. Acetone
D. All of the above
E. None of the above
PHYSIOLOGY – METABOLISM - MCQ
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19. Which of the following is FALSE?
A. Acetone is excreted via respiratory & renal route
B. Ketone bodies are metabolized in liver normally
C. Ketone bodies accumulates as entry of acetic acid into the Kreb cycle is reduced
D. In intracellular glucose depletion, fatty liver results
E. Carbohydrate is antiketogenic
20. Ketosis occurs during:
A. Starvation
B. Diabetes mellitus
C. High fat, low carbohydrate diet
D. All of the above
E. None of the above
21. Brown fat:
A. is found in infants & adults
B. has a sympathetic innervation
C. contain increased amount of mitochondria
D. All of the above
E. None of the above
22. Lipoprotein lipase:
A. is found on the endothelial surface of capillary only
B. activity increases in feeding
C. activity reduces with stress
D. is not controlled by  adrenergic nerve
E. All of the above
23. Elevated cholesterol occurs with:
A. Hyperthyroidism
B. Hyperoestrogenemia
C. Diabetes mellitus
D. All of the above
E. None of the above
24. Which of the following pairing of mineral deficiency & their effects is CORRECT?
A. Iron deficiency – anaemia
B. Cobalt deficiency – megaloblastic anaemia
C. Zinc deficiency – depressed immune system & healing
D. Chromium deficiency – insulin resistence
E. All of the above
PHYSIOLOGY – METABOLISM - MCQ
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25. Acute vitamin A toxicity causes:
A. Headache
B. Diarrhoea
C. Dizziness
D. All of the above
E. None of the above
ANSWERS:
1. D
2. E
3. C
4. A
5. B
6. D
7. C
8. E
9. E
10. B
PHYSIOLOGY – METABOLISM - MCQ
11. D
12. A
13. E
14. C
15. B
16. C
17. A
18. C
19. B
20. D
21. D
22. E
23. C
24. E
25. D
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