MUSCULAR DYSTROPHY
Definition
A group of inherited progressive muscular disorders of unknown etiology.
Symptoms
Presents w/ proximal mm weakness causing waddling gait, toe walking, xs lordosis, frequent falls, difficulty
climbing up stairs or in standing up. Has fatty fibrous infiltration of calf mm.Aka pseudohypertrophy. Often
pt has low IQ (NPLEX)
DDx
Etiology/Epidiemology
There are several subtypes. Pseudohypertrophic or duchenne's M.D. Is most common form. Is sex-linked
recessive d/o -prevails in boys 3-7 yo. Affects pelvic girdle first then shoulder girdle. Progression is steady
and most pts confined to wheelchairs by age 10-12. Extreme flexion contracturs and scoliosis can develop.
Most pts do not live beyond age 20. (N PLEX)
Pathophysiology
Key PE
Key Lab
Diagnosis: sx, fam hx, genetic testing, elevated ck serum enzyme presents early in dz: w/in first months
thru 1st yr or longer-often prior to dev. of sx..(NPLEX)
Strategy
MUSCULAR DYSTROPHY
TX PROTOCOLS
Nutrient Considerations:
1. Vitamins:
a.) E (1,8)
b.) B 12 (8,1)
c.) Folic acid (8,1)
d.) B Complex (8,1)
e.) Multiple vitamin. (1)
f.) Inositol (1)
2. Minerals:
a.) Multi-minerals (8,1)
b.) Selenium (1)
3. Glandulars:
a.) Brain (8,1)
b.) Spinal cord (8,1)
c.) Muscle (1)
d.) Liver (1)
e.) Adrenals (1)
f.) Thyroid (1)
4. Enzymes:
a.) Lipase (8)
b.) Pancreatin (8)
5. Amino acids: a.) Glycine, 5-10gm/day (effective as Gelatin) (1)
b.) Glutamic acid, 10-20gm/day (1)
c.) Carnitine helps w/ Duchenne type (Leibowitz says its in Lit. Noel Peterson E)
6. Other:
a.) Brewer's Yeast (8)
b.) Lecithin (8)
Dietary Considerations
Botanicals:
Strophanthus (1)
Homeopathy:
1. Plumbum met - foot and wrist drop (8)
2. Mercurius (8)
3. Sarcolactic acid (8)
4. Mag Phos 3-6x (8)
5. Calc Fluor 3-6x (8)
6. Kali Phos 3-6x (8)
7. Lathyrus (8)
8. Argentum (8)
9. Picricum acid (8)
10. Phos (8)
11. Conium 12X & Cicuta virosa (8)
12. Causticum (8)
13. Cantharis (8)
14. Hypericum (8)
15. Gelsemium (8)
16. Kali mur (8)
17. Silicia (8)
Physical Medicine:
1. Gentle massage (8)
2. Hydrotherapy on spine (8)
3. Exercise (1)
4. Galvanic and sine wave through spinal cord (1)
5. Hot and cold compresses (8)
Oriental Medicine
Psychology
Other
Ref:
1. Student paper by Tom Ballard, class of 1982.