MSF - Operational Centre Brussels - MEdical Department OCB MEDICAL ACTIVITY REPORT 2012 MSF-OCB - Belgium - Brazil - Denmark - Hong Kong - Italy - Luxembourg Norway - South Africa - Sweden MSF - Operational Centre Brussels - MEdical Department OCB MEDICAL ACTIVITY REPORT 2012 MSF-OCB - Belgium - Brazil - Denmark - Hong Kong - Italy - Luxembourg Norway - South Africa - Sweden OCB Medical Activity Report 2012 MSF-OCB 94 Rue Dupré B-1090 Bruxelles Belgium Technical support & coordination Luxembourg Operational Research (LuxOR) MSF-Luxembourg 68 Rue de Gasperich Luxembourg Compilation and editing Sokhieng Au Rafael Van den Bergh Further information and reprints Dr. Rony Zachariah E-mail: rony.zachariah@brussels.msf.org Tel: + 352 332515 Fax: + 352 335133 MSF MEdical Department OCB CONTRIBUTORS Photographs © Halimatou Amadou, Jodi Bieber, Peter Casaer, P.K. Lee, Robin Meldrum, Andre Quillien, Sami Siva and Sven Torfinn Maps generated using StatPlanet v3.0 MEDICAL ACTIVITY REPORT 2012 Contributors 3 Introduction Bertrand Draguez Biomedical Equipment Vincent Maure Emergency Medicine Pola Valles Emergency Unit Rosa Crestani & Marie-Christine Ferir Epidemiology/Epicentre Fabienne Nackers Evaluation Unit Boris Stringer Health Informatics Armand Sprecher, Marcel Manzi & Rafael Van den Bergh Health promotion and socioanthropology Yasmine Al Kourdi HIV/Tuberculosis Dmytro Donchuk, Eric Goemaere & Helen Bygrave Infection Control Sarah Daho Intensive Care Pola Valles Laboratory Pascale Chaillet Malaria Jorgen Stassijns Medical Structures-Inpatient Department Nadja De Groote Mental Health Nathalie Severy Nutrition Pascale Delchevalerie Operational Research and Documentation Rafael Van den Bergh & Rony Zachariah Paediatric Care Isabel Zuniga Pharmacy Caroline Beetz, Marjolein De Bruycker & Ramon Spatini Bernardo Sexual and Reproductive Health Eva De Plecker Surgical Activities Miguel Trelles Vaccination Catherine Bachy Water, Hygiene and Sanitation Peter Maes Compilation and editing Rafael Van den Bergh & Sokhieng Au Editing Rony Zachariah & Tony Reid Coordination Rony Zachariah 4 MSF MEdical Department OCB 5 7 9 11 12 15 17 19 21 26 29 31 34 36 43 45 47 49 52 56 59 63 67 71 76 80 84 87 91 Contents 01.Introduction 02.Executive Summary 03.List of Abbreviations 04.A Year In Snapshots 05.medical data 06. Biomedical Equipment 07.Emergency Medicine 08.Emergency Unit 09.Epidemiology/Epicentre 10.Evaluation Unit 11. Health Informatics 12. Health promotion and socio-anthropology 13.HIV/Tuberculosis 14.Infection Control 15.Intensive Care 16.Laboratory 17.Malaria 18.Medical Structures-Inpatient Department 19.Mental Health 20.Nutrition 21.Operational Research and Documentation 22.Paediatric Care 23. Pharmacy 24. Sexual and Reproductive Health 25. Surgical Activities 26.Vaccination 27.Water, Hygiene and Sanitation 28.Annex – tables and figures pages MEDICAL ACTIVITY REPORT 2012 Contents 6 MSF MEdical Department OCB Introduction The Medical Department of MSF-Operational Centre Brussels is responsible for guiding and supporting its medical activities in the field. As such, the Medical Department is at the heart of MSF’s identity as a medical humanitarian organisation. I am pleased to present the fifth edition of the OCB Medical Activity Report. With this publication, we highlight the activities of the 22 technical domains of the Medical Department, with the objectives of 1) providing a platform for the accountability of the medical department and highlighting its important role in the OCB operations, 2) maintaining a memory document of the activities and lessons learned over time, 3) enhancing self reflection and critical review of the department and its activities, and 4) demonstrating the scope and depth of our medical activities to our partners and donors around the world. I wish to thank all members of the Medical Department for their hard work over the past year, and for their support in compiling this report. Any feedback on the content or presentation of the report is most welcome, and should be sent to rafael.van.den.bergh@brussels.msf.org and rony.zachariah@brussels.msf.org. Finally, my sincere gratitude goes out to all OCB staff around the world, both at headquarters and in the field, and to all partners for their continued support to MSF activities. 7 With compliments Dr Bertrand Draguez Director – Medical Department Médecins Sans Frontières – Operational Centre Brussels (OCB) Brussels Belgium MEDICAL ACTIVITY REPORT 2012 01. Introduction Tel: + 32 24 74 74 74 MSF MEdical Department OCB Executive Summary 1. Overview of OCB activities In 2012, Médecins Sans Frontières – Operational Centre Brussels (OCB) was active in 28 missions, with 73 projects reporting medical activities. Overall, 2,045,318 consultations in the outpatient department (OPD) were performed and 135,259 admissions to the inpatient department (IPD) were registered. Large-scale emergency interventions focused on refugee care (in Mali, Mauritania and South Sudan) and cholera outbreaks (Guinea, Haiti, Sierra Leone). Geographically, subSaharan Africa continued to be the main region of intervention, though important activities were also performed in North Africa, Asia and the Middle East (fig. 1). Care was provided for: 111,199 HIV patients on antiretroviral therapy (ART), of which 29,925 new cases 277,086 confirmed malaria cases 55,354 with severe acute malnutrition 47,908 deliveries 15,813 new surgical cases More than 370,000 individuals vaccinated for measles during outbreaks 9 219,146 emergency department (ED) consultations 02. Executive Summary Figure 1: Global OCB sections and missions, 2012 OCB Mission OCB Mission & Section MEDICAL ACTIVITY REPORT 2012 OCB Section 2. Year in Review The past year brought a clear reduction of the medical activities of OCB, with reduced numbers in virtually every domain (mental health, nutrition, OPD consultations, sexual and reproductive health (SRH), surgery, TB care, vaccination, etc.), except for malaria (stabilised versus 2011), hospital admissions (slightly increased since 2011) and HIV care (increased ART initiations since 2011). These decreases were usually the consequence of programme closures/handovers, including particularly large projects such as Lashkar- 10 Gah (Helmand), Afghanistan. novel data management tool MINOS was rolled out further, and by the end of the year accounted for 18% of all OPD data and 11% of all IPD data. Additionally, a series of new standardised databases for different medical activities (obstetric, neonatal, ED, and sexual violence care) were successfully piloted and/ or implemented. Analyses based on these novel tools are available in the relevant sections of this report. Concomitantly, the use of routine data to generate evidence for the guidance of operational decisions was expanded, for example with the analysis of 3. Challenges and prospects The reorientation of OCB operations to larger, more specialised projects has strong implications for the Medical Department. While this narrower but more focused medical portfolio within OCB may lead to an improved quality of care, resulting from the higher degree of specialisation and innovation allowed in such projects, it is not without consequences. Investment in a limited number of large projects may carry higher risks than managing a larger number of smaller projects, as closure of one such large project due to for example security issues would lead to a considerable loss of activities and missed vaccination opportunities to steer came an increased depth: projects which OCB vaccination programmes, and the de- were not closed tended to expand – this was velopment of a set of standard Health Pro- noted in particular for SRH, where all overall motion indicators which will be implemented A general trend for 2013 promises to be an numbers were reduced but individual pro- over the course of 2013. This is mirrored by increased focus on transversal or integrated jects often increased and/or refocused their the increased uptake of Operational Re- approaches. This should include better inte- SRH activities. Higher levels of specialisation search (OR) in different topics, such as Water gration of HIV and TB care into non-vertical were noted, e.g. in surgery (where more and Sanitation (WatSan), Laboratory (antibi- programmes, a holistic approach to hospital high-level orthopaedic interventions and spe- otic resistance) and Mental Health & Health management, better integration of vaccina- cialised fistula surgeries were performed), TB Promotion (where initiatives were launched in tion activities in nutrition and HIV pro- care (where higher numbers of multi-drug 2012 and will be formalised in 2013). How- grammes, a comprehensive approach on the resistant TB cases were noted despite an ever, much work remains to be done on the nutritional management of infants younger overall decrease in TB patients in care), “data culture” in OCB, where data manage- than six months, and an emphasis on ration- emergency medicine (where fewer ED con- ment is sometimes considered an imposition al drug use as a cross-cutting health chal- sultations were conducted, but the South from headquarters on the field, rather than an lenge. Such transversal approaches will re- Africa Triage Score system was rolled out intrinsic component of programme evalua- quire close interactions both within the successfully). However, some topics, such tion and improvement. Medical Department and between the Medi- reduction in overall numbers mirrored by higher degrees of specialisation. An increased degree of innovation and doing “more with less” was also noted. Examples are the “light approach” to HIV care implemented in a number of vertical HIV programmes, which succeeded in increasing ART initiation by 25% despite the negative funding climate for HIV, and the use of maternity waiting homes in obstetric care pro02. Executive Summary tion, considerable progress was made. The With a reduced volume of medical activities as nutrition and vaccination, did not see their MEDICAL ACTIVITY REPORT 2012 At the level of data monitoring and evalua- grammes to increase institutional delivery rates (already noted in 2011 and analysed in more detail in 2012). An increased focus on training was also not- expertise. Further discussions on this strategy need to be held. cal and Operations Departments. ed, including specific training on biomedical In addition, an enhanced emphasis on evi- equipment, emergency medicine, intensive dence-based approaches is foreseen during care, aspects of WatSan, and higher levels of 2013. Examples include: close monitoring of on-the-job training for e.g. infection control specific data in the ED and the intensive care and data management. A specific course for unit (both relatively new services within OCB), the training of hospital management teams continuation of thorough missed-vaccination has also been developed and will be rolled opportunities analyses, compilation of a full out in 2013. The first MSF-organised OR inventory of OCB hospital-based activities, training course was finalised in 2012, and and an increased uptake of OR in areas such showed high success rates and outputs, as Health Promotion, Mental Health, WatSan leading to official accreditation of the joint and emergency interventions. These devel- Union/MSF course by the World Health Or- opments will need to be backed up by com- ganisation (WHO). prehensive, standardised and efficient data management tools. MSF MEdical Department OCB OR: Operational Research ORS: Oral Rehydration Solution OT: Operating Theatre PCR: Polymerase Chain Reaction PCV: Pneumococcal Vaccine PEPFAR: President’s Emergency Plan For AIDS Relief PFA: Psychological First Aid PHC: Primary Health Care PHU: Primary Health care Unit PLW: Pregnant and Lactating Women PLWHA: People Living With HIV/AIDS PMTCT: Prevention of Mother-To-Child Transmission PNC: Postnatal Care POC: Point Of Care PPD: Preparation for Primary Departure PSP: Populations in Precarious Situations (course) PTB: Pulmonary Tuberculosis PUC: Pool d’Urgence Congo RDT: Rapid Diagnostic Test REPEPI: Responding to Epidemics (course) RIC: Remaining In Care RIF: Resistance to Rifampicin RUSF: Ready to Use Supplementary Food SAGE: Surgery/orthopaedics, Anaesthesia/ reanimation, Gynaecology/obstetrics, Emergency/ intensive care SAM: Severe Acute Malnutrition SAMU: Southern Africa Medical Unit SATS: South African Triage Score SEU: Stockholm Evaluation Unit SGBV: Sexual and Gender-Based Violence SFC: Supplementary Feeding Centre SOP: Standard Operating Procedure SRH: Sexual and Reproductive Health STI: Sexually Transmitted Infections SV: Sexual Violence TB: Tuberculosis TDF: Tenofovir TFP: Therapeutic Feeding Programme TPR: Termination of Pregnancy on Request UNICEF: United Nations Children’s Fund VHF: Viral Haemorrhagic Fever WaSH: Water, Sanitation, and Hygiene WatSan: Water and Sanitation WFP: World Food Program WHO: World Health Organisation WHS: Water, Hygiene and Sanitation 03. list of abbreviation ICU: Intensive Care Unit IDP: Internally Displaced Persons ILS: Immediate Life Support IM: Intramuscular IML: Immediate Life Support IPD: Inpatient Department IPT: Isoniazid Preventive Therapy ITC: International Technical Coordination ITFC: Inpatient Therapeutic Feeding Centre IV: Intravenous KAP: Knowledge, Attitude and Practice KPI: Key Performance Ïndicators KZN: KwaZulu Natal LCC: Logistics Coordinator Course LN: Long-lasting insecticide-treated Nets LRTI: Lower Respiratory Tract Infection LTFU: Loss To Follow-Up LUXOR: Luxembourg Operational Research MAM: Moderate Acute Malnutrition MCC: Medical Coordinator Course MCI: Mass Casualty Incident MDR: Multi-Drug Resistant MedCo: Medical Coordinator MFP: Medical Focal Person MFH: Modular Field Hospital MH: Mental Health MHS: Management of Health Services MINOS: Medical Information Network for Operational Support MIO: Mobile Implementation Officer MoH: Ministry of Health MRAC: Musée Royal d’Afrique Centrale MSF: Médecins Sans Frontières MUAC: Mid-Upper Arm Circumference MWH: Maternity Waiting Home NA: Not Applicable ND: No Data NDRA: National Drug Regulatory Authorities NGO: Non-Governmental Organisation NICD/NHLS: National Institute of Communicable Diseases/National Health Institute NTP: National Tuberculosis Programme OCA: Operational Centre Amsterdam OCBA: Operational Centre Barcelona OCB: Operational Centre Brussels OCG: Operational Centre Geneva OCP: Operational Centre Paris OD: Operating Department OPD: Outpatient Department MEDICAL ACTIVITY REPORT 2012 ACF: Action Contre la Faim AIDS: Acquired Immune Deficiency Syndrome ALSO: Advanced Life Support in Obstetrics ANC: Antenatal Care ART: Antiretroviral Therapy ATFC: Ambulatory Therapeutic Feeding Centre BCG: Bacille Calmette-Guérin (TB vaccination) BEmONC: Basic Emergency Obstetric and Neonatal Care BIRT: Business Intelligence Reporting Tool BLoC: Basic Logistics Courses BraMU: Brazilian Medical Unit CDC: Centres for Disease Control CEmONC: Comprehensive Emergency Obstetric and Neonatal Care CFR: Case Fatality Rate CMAM: Community Management of severe Acute Malnutrition d4T: Stavudine DBS: Dried Blood Spot DFID: Department for International Development (UK) DPC: Directorate of Disease Prevention and Control DPT: Diphtheria-Pertussis-Tetanus vaccine DR-TB: Drug Resistant Tuberculosis DRC: Democratic Republic of Congo DST: Drug Susceptibility Testing E-Unit: Emergency Unit EAC: Enhanced Adherence Counselling ED: Emergency Department EML: Essential Medicine Llist EPI: Expanded Programmes of Immunisation Eprep: Emergency Preparedness EPTB: Extrapulmonary Tuberculosis ERB: Ethics Review Board Explo: Exploratory Mission FDA: Food and Drug Administration FP: Family Planning GAM: Global Acute Malnutrition GAS: Gynaecology, Anaesthesia, Surgery GDP: Good Distribution Practices GRC: Gondama Referral Centre HAT: Human African Trypanosomiasis HIV: Human Immunodeficiency Virus HP: Health Promotion HQ: Headquarters HR: Human Resources HTC: HIV Testing and Counselling IC: Infection Control 11 List of Abbreviations MSF MEdical Department OCB a year in snapshots Biomedical equipment - To address the increasing demands in terms of biomedical equipment, a staff reorganisation was done, including reinforcement of the team with two Mobile Implementation Officers (MIO). - A biomedical support system was developed to assist missions with complex equipment, in particular hospital projects. - An extensive biomedical training course was organised for the first time for national staff working with biomedical equipment – this course will be repeated over the next years. 12 Evaluation Unit Emergency Medicine - Emergency medical care continued to play a major role in OCB: it was provided in 15 projects across eight countries. - Three evaluations were conducted in 2012; additionally, two from 2011 were finalised and two were planned for 2013. - A total of 219,146 emergency department (ED) consultations were performed during 2012; the ED of Timergara, Pakistan had the highest case load (76,310 consultations). - Collaboration between the four evaluation entities within MSF (Paris, Athens, Vienna, and Stockholm) was formalised, and joint activities on training, evaluations and dissemination were conducted. - The South African Triage Scale (SATS) system, introduced in 2011, was in place in eight ED of OCB by the end of 2012. - New trainings were introduced on Immediate Life Support (ILS) and Basic Assessment and Support of Seriously Ill Patients in Developing Healthcare Systems (BASIC DHS). Emergency Unit - In 2012, the E-Unit was active in 18 countries and was involved in 32 emergency interventions, exploratory missions (Explos) and/or emergency preparedness interventions (Eprep). 04. A Year in Snapshots - In order to ensure better dissemination of study results to the OCB Operations and Medical Departments, several meetings were organised in the offices of OCB during which Epicentre epidemiologists presented the results of their recent studies. These meetings appeared useful and well appreciated. - After the pilot phase of two years, the project has continued as the Stockholm Evaluation Unit (SEU). - A standardised tool for monitoring of ED activity was designed and implemented in six projects. - The largest interventions in terms of medical needs and HR/logistics/financial requirements were the refugee interventions in Maban (South Sudan), Mali and Mauritania, and the cholera intervention in Sierra Leone. - Increased human resources support at headquarters was required for the Syria and Maban, South Sudan interventions. At the field level, 15 field emergency coordinators were active and more than 350 departures for emergency missions were noted. Epidemiology/Epicentre MEDICAL ACTIVITY REPORT 2012 - The latest version of the HIV data collection tool, FUCHIA, was developed and released. - Epicentre conducted six field interventions in collaboration with OCB: Haiti, the Horn of Africa, Sierra Leone, South Sudan (twice) and Zimbabwe. - Clinical and operational research was conducted on vaccine preventable diseases (rotavirus, pneumococcal infections and measles), nutrition, HIV/Tuberculosis, malaria and novel laboratory developments. - The international pool of evaluators now consists of 200 potential candidates. However, not enough work is available for this pool and their full-time availability is thus not ensured. - All evaluations in 2012 were conducted by consultants with an MSF background. This model will be continued: investment in the evaluator pool will be reduced in favour of using external evaluators on a consultancy basis and pairing them with internal MSF evaluators. Health Informatics - The two OCB main routine data tools were the Epicentre outpatient department/inpatient department/gynaecology/obstetrics (OPD/IPD/ GynObs) data collection tools and the new data collection software MINOS – these formed the basis of most analyses presented in this report. - The Epicentre outpatient department/inpatient department/gynaecology/obstetrics data collection tools were used in 12 out of 14 missions where their use was indicated. - The new data collection software MINOS was expanded in projects in Pakistan and South Sudan (including the Maban refugee emergency), and introduced in DRC, Egypt and Somaliland. - Overall, 61% of all OPD patients and 81% of all IPD patients were reported on using the Epicentre tools. For MINOS, these proportions came to 18% and 11% respectively. - Human resources turnover remains a challenge to the collection of good quality data – this was noted in particular during the implementation of MINOS in the Maban refugee emergency (South Sudan). - A combined request for Typology and annual sectional data was sent out to the field – in general, the process went well, but some vertical projects and projects in transition between data tools experienced problems in supplying the data on time. Health Promotion and Socio-Anthropology - Health promotion activities were provided in 32 projects, including three emergency interventions and 29 regular projects. - Collaboration with other MSF sections was initiated through a contact group, which allowed the sections to share experiences, practices, and tools while developing a common approach. - An HIV/TB Patient and Community Support advisor has been recruited to support field capitalisation efforts and promote innovative patient support approaches. This person will be part of the Southern Africa Medical Unit (SAMU) and will be directly responsible for all health promotion activities in vertical HIV/TB projects. - Standard HP indicators have been developed and disseminated but not yet implemented in all projects. HIV/Tuberculosis - OCB has handled the negative funding climate for HIV/TB quite well, by adopting more focused strategies and by implementing more ambitious targets in several of its vertical programmes. - At the end of the year, OCB was supporting 18 vertical integrated HIV/TB projects in 10 countries. Very favourable results were obtained with the “light approach” programmes in Zimbabwe and Malawi. - In case finding activities for HIV, 27,183 patients were tested for HIV and 4.9% tested positive. - A total of 27,396 HIV patients were newly registered in OCB-supported clinics during the year, and 5,960 TB patients were taken in care. - A total of 29,925 adults and children were initiated on antiretroviral therapy (ART) – a sharp increase compared to 2011, as a result of the universal implementation of the higher CD4 count thresholds and introduction of Prevention of Mother-To-Child Transmission (PMTCT) B+ in several projects. - The majority of OCB projects were using Tenofovir-based ART regimens as first line treatment, except for Malawi, Mozambique and DRC. - Among adults on ART, retention in care ranged between 64% and 95%, with a target of 85%. This target may be adjusted to 90% following the rapid implementation of community-based chronic care strategies. - Prevention of malaria was not always sufficiently or correctly implemented during emergencies and in some routine activities. - As a consequence of the decreasing malaria burden, there is a need to improve the diagnostic tools (such as RDT) and protocols for differential diagnosis of malaria, to improve the management of fever in children. Infection Control Medical Structures-Inpatient Department - A major achievement at the level of infection control was the opening of the orthopaedic internal fixation programmes in Tabarre (Haiti) and Kunduz (Afghanistan). The highest standards of hygiene were achieved there, showing that such standards can be attained even in resource-poor settings. - OCB has been increasingly involved in secondary healthcare: in 2012, a75 million were dedicated to running IPD structures in 16 different countries, including in emergency contexts, numbering a total of 2,088 beds and catered for by approximately 5,794 staff. - Infection control is more and more integrated into all programmes, with an infection control officer and infection control committee present in most health structures. - A multidisciplinary infection control working group has been created at OCB to allow a holistic approach to infection control. Intensive Care - The focus of OCB is to achieve a good standard of care in basic level Intensive Care Units (ICU). - The two ICUs reporting data in 2012 (Kunduz, Afghanistan and Tabarre, Haiti) saw a total of 506 admissions over the course of the year. - In 2012 OCB provided inpatient care in 30 health facilities, including in four during emergency interventions. - Compiling an inventory of all hospitals in OCB was more challenging than anticipated, but has now been performed. Data is being actively shared with OCP and OCBA. - The Gondama Referral Centre (GRC) in Bo, Sierra Leone, and the hospital in Masisi, DRC were the largest remaining hospitals by the end of 2012 in terms of admissions, staff and bed numbers. - Due to project closures, only two hospitals with sizeable paediatric populations remain: the GRC in Sierra Leone and Guidan Roumdji in Niger. - The high level, technically advanced ICUs in OCB have suffered from the level of complexity they bring, in particular at the level of recruiting and retaining sufficiently trained staff. - A course for the training of Hospital Management Teams has been developed, and will be provided over the course of 2013. - Better documentation and analysis of ICU performance and outcomes are required to improve the ICU activities in OCB. Mental Health Laboratory - At the end of 2012, 35 laboratories provided lab support in 34 projects: the major areas receiving laboratory support were HIV/TB care, blood transfusion and hospital services. - More automated solutions for support of advanced laboratories, such as mobile network connectivity options, are urgently required. - A major laboratory-based operational research study on antibiotic resistance in Lashkar-Gah (Helmand), Afghanistan was ongoing, and results are expected by 2013. Malaria - 476,056 Rapid Diagnostic Tests (RDT) were performed, with high positivity rates (i.e. high malaria endemicity) in projects in South Sudan, Mauritania, Niger, Sierra Leone and DRC. - During 2012, OCB provided mental health (MH) activities in 24 regular projects across 15 countries and in an additional five emergency interventions. - The portfolio of MH interventions was reduced for ongoing projects, as a result of the closure of seven projects/MH components. New MH projects mainly developed as additional components of projects in countries with pre-existing activities. - New projects with a strong MH component were the Maban refugee intervention in South Sudan (with a focus on the therapeutic feeding programme, activities at the main clinic and health posts, and awareness activities in the community) and Egypt (comprehensive medical and MH care for migrants in Cairo). - Contacts were made with external partners to develop an Operational Research portfolio on MH. - 22 nutritional projects across 13 countries were managed by OCB; no new projects were opened (except for the emergency projects in Mali, Mauritania and Maban (South Sudan) and two major ones were handed over (in Sierra Leone and Niger). - 55,354 patients with severe acute malnutrition were admitted to Intensive or Ambulatory Therapeutic Feeding Centres and 298 patients with moderate acute malnutrition were admitted to Supplementary Feeding Centres, representing the lowest levels since 2008. - 3,831 patients benefited from selective feeding (in one single project), and 612 patients received specific targeted nutritional support – also representing a sharp decline since the previous years. - No General Food Distributions were done in 2012. - For the projects providing outcome data, two out of 15 achieved the target cure rate of >80%, while eight remained below 70%. Low cure rates were typically linked to high defaulter rates, even in refugee settings such as Maban (South Sudan) and Mauritania. In Mauritania, these defaulter rates were reduced significantly by interacting with the community. - The Kamrangirchar project in Bangladesh has developed into a focus project for Operational Research (OR) into nutrition and nutritional approaches in Asia in particular. The first publications based on the research conducted in Bangladesh were released in 2012. Operational Research and Documentation 13 -In vertical HIV programmes reporting on PMTCT, 92% of all women attending antenatal care (ANC) were tested for HIV, 87% received a full PMTCT intervention and transmission rates were limited to 3%. - Injectable artesunate was rolled out as new treatment for severe malaria – its implementation seems feasible in the field. Nutrition - 2012 saw the completion of the first MSF-led OR course in Luxembourg (initiated in 2011), and the launching of two new courses managed by MSF in Europe and in Africa. Excellent outcomes were achieved for these courses, with 88% of the participants meeting all their milestones, and a 12-month and 24-month publication success rate of 77% and 93% respectively. - 81 OCB-related peer-reviewed papers were published, the main topics being HIV (14%), health programme monitoring and management (12%), TB (11%), HIV/TB co-infection (11%), and Operational Research (11%). The MSF courses were a driving force behind the strong increase in publications in 2012. - 72 study protocols were developed over the course of 2012, 48 of which in the context of the OR courses. - The first OR Day was organised at OCB. It was considered a great success in terms of enhancing the credibility and perceived value of OR in MSF, and will henceforth become a yearly event. -Several studies have influenced policy and practice. One OR study, on the reduction of maternal mortality in Burundi and Sierra Leone, received massive press attention, featuring in an international documentary leading to discussion with the European Commission Development Cooperation Directorate. 04. A Year in Snapshots - A total of 495 patients were initiated on treatment for multidrug-resistant TB (MDR-TB) across ten different OCB projects. - The numbers of malaria cases stabilised versus 2011, at 277,086 confirmed malaria cases treated by OCB; 90% of these cases were treated in four missions only: DRC, Niger, South Sudan and Sierra Leone. MEDICAL ACTIVITY REPORT 2012 - TB treatment outcomes were variable: only two projects achieved the target treatment success rate of >85% for smear-positive pulmonary TB. Death rates exceeding the 10% threshold were observed in three projects, and treatment interruption rates >10% in another two. Only one project had a >85% treatment success rate among smear-negative pulmonary TB and extrapulmonary TB cases. - A document outlining the vision, goal, strategies and outputs of the Union-MSF OR group was written up and will be published over the course of 2013. Paediatric Care - 673,274 (37%) of all outpatient consultations and 35,435 (48%) of all hospital admissions in OCB were for children under five. - The leading causes of morbidity for paediatric outpatients were similar to the previous years: respiratory tract infections (39%), malaria (18%), non-bloody diarrhoea (16%), skin infections (5%) and eye diseases (4%); for paediatric inpatients, the major morbidities were severe malaria (33%), lower respiratory tract infections (17%), neonatal pathologies (10%) and nonbloody diarrhoea (9%). - The leading causes of paediatric inpatient mortality were severe malaria (27%), neonatal pathologies (26%), lower respiratory tract infections (12%), septicaemia (5%) and non-bloody diarrhoea (3%). - Neonatal pathologies as a proportion of under five IPD morbidities increased from 5% in 2011 to 10% in 2012, primarily due to better reporting: for the first time in 2012, neonatal diagnoses were systematically included in the Epicentre IPD tools. 14 - In emergency obstetrical programmes, there is a need to think about neonatal services from the outset, since 10- 20% of babies may need inpatient care. - Concerning tuberculosis (TB), a total of 333 cases (0.1% of all morbidity) were suspected in under five children, showing that little measurable improvement has been made in case detection and/or reporting of TB at the health centre level. Pharmacy MEDICAL ACTIVITY REPORT 2012 04. A Year in Snapshots - The emergencies in Syria and South Sudan and the increased activities in countries with import constraints such as Ukraine, Afghanistan, Pakistan and India continued to represent significant challenges to the medical supply chain. - Major changes occurred at supply level with the move of the MSF Supply site from Merchtem to Neder-Over-Heembeek, the start of the new Supply Unit under a unique Supply & Logistics Support Director, contributing to the restructuring of MSF Supply departments, and the creation of a Supply Chain director position. - Fifteen products were validated by MSF pharmacists. - Two batch recalls and seven quality alerts concerning OCB projects were issued during 2012 - An evaluation of the local pharmaceutical market was conducted in 12 countries: 14 manufacturers were approved in six countries, and 69 wholesalers were approved. - Total expenditure for medical procurement was 22.1 Ma, with an additional 1.6 Ma for therapeutic food. - Collection of data on local purchases and donations has improved slightly, but still needs to be strengthened and implemented by all missions. However, collection of stock management indicators with reporting on losses was far from successful and will remain a major challenge. Sexual and Reproductive Health - Sexual and Reproductive Health (SRH) saw a reduction in its activities across the board, mainly due to project closures/handovers and reorientations. In 2012, 40 projects provided SRH components – the projects which remained tended to expand their SRH activities. - Antenatal care was offered in 24 projects and 169,672 antenatal consultations were performed – adequate antenatal care coverage (four visits during pregnancy) remained low. - Deliveries were conducted in 27 projects, all of which offered emergency obstetric care and 16 provided Caesarean sections and blood transfusion. 47,908 deliveries were performed, 5,411 of which by Caesarean section. - Postnatal care was offered in 23 projects and 18,985 postnatal consultations were conducted. - Family planning was offered in 27 projects and 47,662 family planning consultations were conducted. - Termination of pregnancy on request was offered in 13 projects and was provided for 1,636 women. - Management of obstetric fistula included two fistula campaigns (in Masisi, DRC and Gogrial, South Sudan) and the long-term project in Gitega, Burundi, offering holistic care for fistula patients. Overall, 551 surgical fistula repair interventions were provided. - Care for survivors of sexual violence was offered in 22 projects, though only 16 projects reported cases of sexual violence: 2,909 cases were seen. - An SRH in emergencies toolkit has been developed to accommodate for the increasing implementation of SRH activities in emergencies. Surgical Activities - Surgery in OCB focused on providing 1) essential, life-saving surgery, with low-tech requirements; 2) high-standard orthopaedic care in selected projects; and 3) specialized surgical care to women with obstetric fistula in various locations. -Operating department data coverage and quality continued to be high. - 22 OCB projects offered surgical care; for 19 of these OCB was directly responsible for all aspects of surgical care. - 15,813 new surgical cases were seen. - The operating department admitted 20,443 surgical cases; 89% of which were emergency cases. Vaccination - 27 OCB projects provided data on vaccination activities; this represents an underestimation, as some projects with vaccination activities did not manage to provide vaccination data. - A total of 343,678 routine vaccinations were administered in OCB projects during 2012, representing a 12.4% decrease since 2011. This decrease is distributed equally between routine and post-exposure vaccinations. - Vaccination activities are mainly offered in outpatient departments and at antenatal consultations; vaccination in nutrition activities and in vertical HIV projects was not reported at all in 2012. - Tetanus continued to be the most administered antigen (31%) in routine activities, followed by polio (26%) and the diphtheria-pertussisteta­nus or pentavalent (diphtheria-pertus­­sistetanus- Hepatitis B-Haemophilus influenzae type B) vaccine (19%). - The vaccination follow-up in OCB programmes is poor: drop-out rates in the pentavalent vaccine from the first to third dose among children were 38%, while drop-out rates for tetanus vaccination among pregnant women between the first and the third dose was 78%. - More than 370,000 vaccinations for measles were conducted, mainly during major outbreaks in DRC and South Sudan. - Results of six evaluations indicated that missed vaccination opportunities varied between 15% and 48% in children and between 14% and 30% in women of childbearing age. Water, Hygiene and Sanitation - Scanning for Water, Hygiene and Sanitation (WHS) challenges was done systematically, and WHS was involved in almost all ongoing projects. - A focus was placed on providing expert WHS support to established missions, while the WHS needs in complex emergencies were managed by polyvalent technical staff with technical support from headquarters. - Specific WHS interventions focused on borehole rehabilitation in Niger, water source detection in South Sudan, WHS infrastructure installation in the refugee camps in Maban (South Sudan) and Mauritania, and outbreaks of viral haemorrhagic fever in DRC and Uganda. - Three WHS-associated studies were published during 2012, and at least nine WHS study protocols were developed. MSF MEdical Department OCB Medical DATA 1. Overview An analysis is provided of general outpatient and inpatient department (OPD/IPD) data in OCB, as these topics are not covered explicitly in the subsequent sections of this report. For the analysis here, only projects implementing the Epicentre data tools were included, as the other data collection systems in place (Typology, customised project databases, etc.) do not allow refinement of the programme activity data. In the future, data collected through MINOS (cf. Health Informatics section, §2.2.) will also be included in this section. 2. Data analysis and Maternity and Intensive Therapeutic 58,855 inpatient admissions were reported Feeding Centre (ITFC) admissions, repre- (compared to 66,717 in 2011). 2.1. Typology – overall activities senting a modest increase of 4% compared Based on the 2012 Typology data collection, covering all OCB projects, 2,045,318 outpatient consultations were conducted, includ- 2.2. Epicentre data tool analysis 2.2.1. OPD consultations The 2012 distribution of OPD consultations by country and as a proportion of the total OPD consultations is indicated in figure 1. ing consultations in the OPD (1,816,100), The use of the Epicentre data tools is dis- The highest proportion of OPD consultations antenatal and postnatal consultations, family cussed elsewhere in this report (cf. Health In- reported through the Epicentre tools were in planning consultations, Emergency Depart- formatics section,§2.1.). A global summary of Afghanistan (24%), followed by Niger (22%) ment (ED) visits, etc., representing a de- all data collected using the Epicentre tools is and DRC (17%). crease of 5% compared to 2011. In parallel, presented in table 1 (annex): a total of 135,259 hospital admissions were regis- 1,095,373 outpatient consultations were reg- 2.2.2. IPD admissions tered, including admissions to the IPD proper istered (compared to 1,309,649 in 2011) and The 2012 distribution of IPD admissions by 15 to 2011. country as a proportion of the total IPD admissions is indicated in figure 2. The highest Figure 1: Distribution of OCB OPD consultations by country in 2012 proportion of IPD admissions was observed in Afghanistan (36%) followed by Niger Sierra Leone 5% (22%), DRC (15%) and Sierra Leone (15%). North Sudan 3% Afghanistan 24% The proportion of adverse outcomes among all exits is shown by country for 2012 (fig. 3). For most countries, the proportion of discharges with medical agreement met the tar- Niger 22% get of > 85%, except in India and Afghanistan where it was respectively 82% and 80%. The proportion of discharges without medi- Mali 0% cal agreement was under the acceptable threshold of 10% in all the countries except Kenya 11% DRC 17% India (15.1%) and in Afghanistan (13.5%), though it was reduced by 50% in India and by 9% in Afghanistan since 2011. The mor- Haiti 6% Ethiopia 3% tality rate was higher than the acceptable threshold of 5% in three countries: Sierra Leone (8.0%), Afghanistan (6.4%) and Niger (5.2%). MEDICAL ACTIVITY REPORT 2012 India 5% DRC: Democratic Republic of Congo 05. medical data Bangladesh 4% Figure 2: Distribution of OCB IPD admissions by country, 2012 Somaliland 1% Sierra Leone 15% North Sudan 1% Afghanistan 36% Niger 21% Mali 0% India 3% Haiti 7% DRC 15% Ethiopia 1% DRC: Democratic Republic of Congo Figure 3: Proportion of adverse IPD outcomes (inpatient deaths, discharges without medical agreement and defaulters) among all inpatients exits, by country, 2012 % Defaulters % Deaths 05. medical data MEDICAL ACTIVITY REPORT 2012 So m al ila on Le Si er ra Su th or nd e n da er ig N Countries DRC: Democratic Republic of Congo N i al M a di In ti ai H ia op hi Et DR ta is an Af gh C Accepted threshold ≤ 5% n Proportion adverse outcomes 16 % Discharges 100 90 80 70 60 50 40 30 20 10 0 MSF MEdical Department OCB Biomedical Equipment 1. Overview With the substantial increases in the use of advanced medical equipment in OCB projects, the need for technical support has concomitantly increased. Fortunately, to address this need, OCB reinforced the Logistics back office in 2012 with two Biomedical Mobile Implementation Officers (MIOs). With the organisational changes over recent years in all MSF sections, field support for biomedical equipment has increased to currently include: Operational Centre referents: a biomedical referent in OCB and all other centres (part-time in OCBA) Supply centres: a biomedical engineer in MSF Supply and MSF Logistique MIOs: two in OCB, three in OCP, one in OCG, and one likely to be added to OCA in 2013 Biomedical expats: one in Afghanistan (OCB) The OCB Logistics department recruited two MIOs to reinforce the support for biomedical equipment. Coordinated by the Biomedical referent (of the Medical Department), their priorities are determined in collaboration between the Operations Department and the documentation, and guidelines for all equipment. - Ensure that preventive maintenance is undertaken as recommended. - Implement MSF standard tools (both softand hardware). - Record and file all performed maintenances. Logistics back office coordinator. These A correct implementation of this system re- MIOs are key in efforts to create and strength- quires two initial field visits with a six months en a biomedical equipment support system interval to allow time for ordered materials to for all missions with substantial complex arrive, and annual follow-up visits. medical equipment, with hospital projects as the first priority. This support “system” is in- 2.2. Field visits tended to: A number of field visits providing technical - Assure all users are familiar with the use support were performed by the referent in The two MIOs visited: -The Gondama Referral Centre (GRC) in Bo, Sierra Leone. - The health structures of the Kabezi, Kirundo and Gitega projects in Burundi. - The health structures of the Kabul, Kunduz and Lashkar-Gah (Helmand) projects in Afghanistan. - Burao hospital in Somaliland. - The health structures of the Gogrial, Pibor and Maban (Doro) projects in South Sudan. 3. Training and human resources Previously, a small biomedical module was provided in the Preparation for Primary De- and daily maintenance of their equipment, 2012 to the health structures of: and provide training as needed. - The AIDS project in Kinshasa, DRC – tech- Courses (BLoC). In 2012, a more extensive nical training for mission staff was also pro- biomedical training course was developed. vided. Extending over five days, the training was in- - Recruit and train technicians. - Ensure correct installation of equipment. - Manage the equipment inventory. -Maintain stocks with sufficient backup equipment, spare parts and consumables, while ensuring that orders are completed. - Kabezi and Gitega projects in Burundi. -Martissant, Tabarre and the projects of OCA/OCG/OCP in Haiti. 17 2.1. Technical support - Maintain a library with manuals, supporting parture (PPD) course and the Basic Logistics tended mainly for national staff, but was designed for all technicians and supervisors working with biomedical equipment in the field. As a collaboration between OCA/OCB/ OCG, the course was provided three times in both French and English during 2012. It has proved to be successful, and the model will 06. Biomedical Equipment 2. Programme activities be repeated in 2013. MEDICAL ACTIVITY REPORT 2012 - - - - 4. Looking back and ahead Lessons learned for 2012 Due to the complexity of biomedical equipment in MSF projects, full support could not be provided in all cases, due to the lack of speciallytrained engineers equipped with the necessary, often expensive, parts and tools. Such complex medical equipment includes multiparameter monitors, ultrasound machines, x-ray machines and other advanced laboratory equipment. In the case of x-ray machines and some advanced laboratory equipment, transport to Europe for repairs is unfeasible, and local solutions must thus be sought. Results of such local or regional interventions have been variable, and a systematic solution to this challenge has not yet been formulated. In particular, several new x-ray machines have been installed over the last few years, many of which encountered problems that proved difficult and time-consuming to resolve. Prospects for 2013 The referent will focus field visits on HIV/TB projects to assess the current situation and investigate technical support from local companies. The goal is to improve the provisioning of technical support in such missions. Together with MSF Supply, the possibility of negotiating more advantageous contracts when purchasing equipment that needs local support will be explored. For example purchase and service contracts with the “mother” company in Europe on equipment that will be supported by local companies will be examined. The implementation of Biomedical MIOs will hopefully significantly improve the existing biomedical equipment support after MEDICAL ACTIVITY REPORT 2012 06. Biomedical Equipment 18 the first year. Results will be assessed after one year and future strategies will be developed accordingly. MSF MEdical Department OCB Emergency Medicine 1. Overview The Emergency Department (ED) provides health care for outpatients requiring immediate assistance, whether for a life-threatening condition (emergency) or a non-life threatening condition (urgency). The services provided in the ED include initial triage, evaluation, diagnosis, stabilization, treatment and observation of patients demanding immediate care. In most cases the department is integrated into a hospital and has an essential relationship with other services in the health facility, such as surgery, imaging and hospitalization. The department should operate 24 hours a day, seven days a week. During 2012, ED activities continued to play an important role in OCB projects, as MSF continued to be increasingly involved in secondary and tertiary level care settings. New EDs were opened during 2012 in Haiti, Pakistan and Somalia. Freestanding units are confronted with many 2.1 Activities at project and mission level other services needed for the continuity of challenges, as they are not supported by the patient care. Their staff needs to be well- vided in 15 OCB projects across eight differ- defined referral system needs to be in place. 2.3.1. Data collection During 2012, ED data was collected with different tools, varying by country. By the end of the year, six projects were using the stand- ent countries: Afghanistan, Democratic Re- In contrast, hospital-based EDs usually have ardized individual-based data register devel- public of Congo (DRC), Haiti, India, Pakistan, a complete backup system, which includes oped specially for the emergency depart- Sierra Leone, Somalia and South Sudan (not an operating theatre and hospitalization ments (cf. Health Informatics section, §2.3.). including emergency care given by the Emer- wards, where quality care can be continued. The use of this tool permits each project to gency Pool projects). In 2012, OCB had 13 projects with such a better understand, monitor and evaluate its setting. There are important differences be- activities, while facilitating an overall com- tween these EDs, as some receive general parison of ED activities between different emergencies where a wide range of patholo- projects and countries. Most of the remaining gies and patients are treated, while others projects collected ED data with the standard are specialized centres, such as the paediat- MSF aggregated data tool, the Epicentre ric emergency centre in Gondama Referral tools (cf. Health Informatics section, §2.1.). sultations were performed in regular projects during the reported period (table 1, Annex). The ED in Timurgara (Pakistan) had the highest patient caseload (76,310 consultations). Centre (GRC) in Bo, Sierra Leone, or the 2.2. ED Structures In most OCB projects with ED activities, the ED is integrated into a hospital (hospitalbased Emergency Departments). By the end trauma centres in Kunduz (Afghanistan) and Tabarre (Haiti). The Tabarre centre also treats other surgical emergencies. ED indicators on the use of services and quality of care, together with surveillance of specific epidemiological markers, were incorporated into the logical frameworks of spe07. emergency medicine A total of 219,146 emergency medicine con- cific projects. of 2012 only two EDs - Martissant in Haiti and Karachi in Pakistan - were operating as freestanding EDs. Table 2: OCB emergency departments using the SATS system – priority category proportions during 2012 Country Project ED High acuity proportion Percentage of red cases Percentage of orange cases Sierra Leone Somalia Kabul Afghanistan Kunduz Martissant Haiti Tabarre Karachi Pakistan Timergara GRC - Bo Burao 13.3 13.8 12.2 29.3 33.0 23.8 61.9 22.5 3.2 1.7 2.0 3.2 2.1 5.0 34.6 5.6 10.1 12.1 10.1 26.1 30.9 18.9 27.2 16.9 Percentage of yellow cases 39.9 47.3 42.0 61.9 63.1 36.7 25.6 41.4 Percentage of green cases 44.3 38.4 45.9 8.8 3.6 39.1 12.6 36.1 ED: emergency department; GRC: Gondama Referral Centre MEDICAL ACTIVITY REPORT 2012 In 2012, emergency medical care was pro- qualified to stabilize severe cases, and a well- 2.3. Specific activities 19 2. Programme activities 2.3.2. Triage In 2011 the South African Triage Scale (SATS) system was adopted by OCB and implemented for the first time in Timergara (Pakistan); by the end of 2012 this triage system was already in place in eight OCB EDs. The main objective of triage implementation is to The GRC in Sierra Leone has the highest as the medical coordinator course (MCC), proportion of severe patients; 86% of pa- management of health services (MHS), and tients seen in this ED are children under five the medical coordinators week. Specific years of age. training on mass casualty incidents (MCI) tri- 3. Human resources and training allow early identification of the sickest pa- The ongoing challenges around human re- tients, reduce patient mortality, and decrease source capacity for emergency medicine waiting times, thereby improving overall sat- continued to be tackled through close col- isfaction and quality of care. laboration with the pool managers and re- The SATS system permits the categorization of patients into different priority groups (table 2): the red category indicates the most severe cases and the green category indicates cruiters. Emergency medicine doctors are clearly identified as a separate pool and the profile for emergency medicine nurses is now fully established. patients that have no signs of emergency or Emergency care in MSF continued to be pro- priority and therefore are not urgent cases. moted through internal training courses such age was offered, and management and planning was provided successfully to several groups. In collaboration with the Italian Resuscitation Council, a training workshop on Immediate Life Support (ILS) adapted to field needs was run in Haiti shortly before the opening of Tabarre hospital. To respond to the need for specific training in the management of severe patients, the Basic Assessment and Support of Seriously Ill Patients in Developing Healthcare Systems (BASIC DHS, cf. Intensive Care section, §3.) training also took place in Haiti during 2012. 4. Looking back and ahead Lessons learned for 2012 - To better understand and improve our emergency medicine activities, better monitoring and evaluation of these activities needs to take place through the implementation of effective surveillance systems. 20 - Measures to ensure greater standardisation of care in our emergency departments need to continue in order to improve the quality of care delivered. Prospects for 2013 - The implementation of the data collection tool in the EDs will be further monitored and supported. - The care provided in new EDs will be further standardised, and current recommendations for the running of these projects will be assessed and revised where necessary. - The OCB Toyota Land cruiser ambulance will be launched and its adequacy under field conditions (urban and rural settings) will be evaluated. - Expatriate staff will continue to be followed up by the emergency medicine referent. - Relevant emergency care trainings will be included in the HQ training list and the international guidelines will be rendered MEDICAL ACTIVITY REPORT 2012 07. emergency medicine accessible and useful to field teams in differing contexts. - The MSF catalogue will be updated for emergency care drugs and equipment. MSF MEdical Department OCB Emergency Unit 1. Overview The emergency unit (E-Unit) oversees the direct management of emergency projects and supports emergency interventions managed by the operational cells. In 2012, the E-Unit was active in 18 countries and was involved in 32 emergency interventions, exploratory missions (Explos) and/or emergency preparedness interventions (Eprep). Of these, 18 were direct emergency interventions/ Explos and 14 involved support to cells in charge of emergency management, or human resources (HR) support for regular projects in conflict contexts. Four Eprep activities were conducted during the year. Major interventions in 2012 were assistance to refugees in South Sudan, the Sahel intervention (Mali and Mauritania) following the conflict in Mali, the malaria outbreak in DRC, the Syria intervention and the cholera outbreak in Sierra Leone. Several of these are discussed in more detail below. 2.1. Emergency activities in 2012 Managed by the E-Unit Reason for intervention Comments Brazil Illegal Haitian migrants In collaboration with the Brazil office Over the course of 2012, 32 interventions (di- Philippines Floods Exploratory/short intervention rect and support) were performed by the E- Syria-Lebanon-Turkey Conflict Unit (table 1). These included management Libya Conflict Handed over in February of disease outbreaks, care for internally dis- Mauritania Refugees + nutrition placed persons (IDP) due to conflicts and Mali Conflict + nutrition natural disasters, care for refugees/migrants, South Sudan Measles care for war wounded, and several nutritional South Sudan Refugees emergencies related to IDP and refugees. Sierra Leone Cholera I Sierra Leone Cholera II DRC Malaria Uganda VHF – Marburg Somalia Nutrition - measles - cholera- IDP Mogadishu and Guriel 2.2.1. Refugee intervention in South Sudan Support to cell Malawi Floods Expertise In November 2011, an intervention to assist Guinea Cholera Tech support refugees fleeing the Blue Nile State in Sudan Uganda VHF – Ebola I Tech support & HR to OCBA was initiated in Maban county, South Sudan: DRC VHF – Ebola II Tech support & PUC-HR to OCBA OCB worked in three refugee camps (Doro, Brazil Evaluation of emergencies Tech support Zimbabwe Typhoid fever Tech support Belgium Migrants Support Brazil Emergency study/assessment Tech support Batil, and Jamam) in the region. The E-Unit was involved in this intervention from May 2012 onward, to manage the new influx of refugees at Batil camp and to complete the set-up of activities at Doro camp. Comprehensive packages were provided in Batil and Doro camps. The activities in Jamam camp were handed over to OCA in June 2012 and in Batil camp on the first of December. Mobile clinics were set up from the beginning of 2012 to cover the new influx at the border sites, performing a total of 3,620 consultations in 2012. Eprep South Sudan War wounded Sierra Leone Cholera Mali War wounded and cholera Mauritania War wounded and cholera DRC: Democratic Republic of Congo; Eprep: emergency preparedness; HR: human resources; IDP: internally displaced persons; OCBA: Operational Centre Barcelona; PUC: Pool d’Urgences Congo; VHF: viral haemorrhagic fever 08. emergency unit 2.2. Major emergency response activities in 2012 21 Table 1: Emergency activities managed by the E-Unit (direct, support and Eprep), November 2011 to October 2012 MEDICAL ACTIVITY REPORT 2012 2. Programme activities Medical care, sexual and reproductive health refugees (between 40,000 and 50,000 dur- and antenatal care (ANC), a nutritional pro- ing 2012). gramme, a mass measles vaccination for children, a mental health component, and health promotion activities were carried out at all 22 08. emergency unit nou, with a total of 7,851 consultations during the year. - A nutritional survey in November to assess the status of the children and their vaccina- three sites. A total of 197,605 medical consul- The intervention concerned four of the five tations were performed at the three sites, the districts of this region. The team worked in majority at Doro camp. The top causes of Ministry of Health (MoH) structures, opening morbidity in the three camps were lower res- (or re-opening) four Inpatient Therapeutic piratory tract infections, malaria and diar- Feeding Centres (ITFC, locally termed URE- rhoea. 1,436 deliveries were performed, the NI) and 16 Ambulatory Therapeutic Feeding vast majority (83 %) at Doro, due to the lack of Centres (ATFC, locally termed URENAS). The time in building relationships with traditional intervention treated in total 1,653 children birth attendants at the other two camps be- under five years of age, with a default rate of fore those projects were handed over to nearly 25%. The high rate of the defaulters OCA. 12,061 ANC consultations were per- was mainly due to the semi-nomadic nature formed overall, and a total of 5,665 patients of the populations treated. The intervention were admitted to the malnutrition programme. included several activities: the logistical set- During the year, across several campaigns, up of the areas for treating the malnourished, 83,613 measles vaccinations were provided training and incentives for the MoH staff, and to children between six months and 15 years provisioning of medical and non-medical Approximately 16,500 children were vacci- of age. The Expanded Programme of Immu- items for the activities. The activities were nated for measles, and the intervention sup- nisation (EPI – including BCG, tetanus, and handed over to the MoH at the end of the ported the routine MoH immunisation pro- polio) was also offered in Doro camp, and in year, as a nutritional crisis did not materialise gramme with the standard vaccines. Health Batil at the end of the year. during the dry season. promotion (HP) was very difficult to imple- 2.2.2. Sahel intervention (Mali & Mauritania) MEDICAL ACTIVITY REPORT 2012 2.2.2.1. Assaba nutritional intervention (Mauritania) - Support to the health centre in Bassikou- Explos were conducted in Mauritania and Mali following the food crisis first noted in early 2012. A nutritional intervention was mounted in the Assaba region of Mauritania and in the Mopti region of Mali; these interventions were predominantly preparedness measures in view of the worsening food crisis, rather than a full response to an existing nutritional crisis. 2.2.2.2. Mbera refugee camp intervention (Mauritania) tion coverage (approximately 13% global acute malnutrition (GAM) and less than 70% of measles coverage). The three ATFC and the ITFC admitted a total of 3,877 patients - an additional 297 cases were enrolled at the ATFC of Fassala. Overall, 37% recovered fully, while a high default rate of 48% was observed, due mainly to the movements of the population and misunderstandings on the services offered. Several interventions were undertaken to improve the default rate, and by the end of the year it had been reduced to 20%. ment, mainly due to a lack of qualified personnel during most of the year. Only nutritional screening and active research of OCB initiated activities in Fassala village (the defaulters was possible. A focus will need to entry point for the refugees from Mali) on be placed on improving the HP component March 5th 2012, followed by activities in Mbera in 2013. camp itself. These activities included: - Primary health care in the camp and in the surrounding villages (five outpatient departments, ATFC’s and health posts for preventive activities: three in the camp and two in the villages of Fassala and Mbera). In Fas- MSF is continuing the above activities in 2013, and indeed, the arrival of new refugees (approximately 70,000) in the camp in January has increased the need for more aid and consequently for more HR. A full medical intervention in Mali was pre- sala, 17,243 consultations were performed cipitated by the geopolitical events in the during the year, while the three OPD’s of country, when radical Islamist groups took Mbera performed 60,207 consultations. In response to the food crisis, a nutritional pro- control of the north of the country after the Respiratory tract infections and diarrhoea gramme (supporting MoH structures) was im- separatist MNLA Tuareg movement ousted were the main pathologies for the outpa- plemented in Mopti; during six months in 2012 the national army from the region (declaration tient consultations; malaria was present for there were 1,451 new admissions. The recov- of the State of Azawad in April 2012). In the only half of the year (seasonal from June to ery rate was approximately 70%, with a de- internal turmoil that followed, the Malian November). faulter rate of more than 25%. This was mainly president was overthrown by another faction, -Secondary health care in the camp of and a transitional government was installed Mbera (one hospital with an inpatient de- in the south. These conflicts led OCB to in- partment (IPD), maternity, and ITFC). The tervene in the north in the Douentza district IPD received 1,286 admissions, with a (support to Gao hospital for a few weeks) 90.7% recovery rate. The maternity pro- due to the deterioration of the health system, vided 2,161 primary ANC consultations , degradation of the population’s nutrition and 1,426 follow-up consultations, and 465 health status and general problems of ac- deliveries. OCB assisted in another 225 cess to health care. deliveries in the Fassala health post and Simultaneously, refugees fleeing the conflict 146 in the Bassikounou health centre. 2.2.2.3. Mali nutritional intervention due to movement of the population, lack of a decentralised system, and lack of access in several areas because of flooding during the rainy season. The average weight gain remained on target (7g/kg/day), as did the average length stay in the programme (36 days). The main causes for morbidity at registration at the ATFC were malaria (36.7%), respiratory tract infections (18.2%), and diarrhoea (18.8%). Similarly, the main reasons for ad- started to arrive in Mauritania; OCB inter- - Planning for the opening of an emergency mission to the ITFC were malaria (35.2%), vened in the camp of Mbera in March to pro- surgical unit in Bassikounou (completed in diarrhoea (28.2%) and respiratory tract infec- vide health care and nutritional support for January 2013). tions (19%). Figure 1: Cholera cases in the Western Area of Sierra Leone, week 1-39, 2012 (MoH data) Cases CFR Number of cases 1400 4,0 1200 5 1459 4,4 4,5 1200 1140 1240 4 1117 955 1000 800 3,5 903 3 757 2,2 660 2,5 621 600 1,6 400 1,2 189 200 1 2 3 4 5 6 7 8 9 1,5 1,0 0,6 25 45 11 0 1,3 2 476 1,3 1 0,5 0,4 0,2 Case Fatality Rate (CFR) 1600 0,5 0,3 0 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 Epidemiological weeks 2.2.2.4. Mali North intervention (conflict) Figure 2: Case Fatality Rate at MSF Cholera Treatment Centres in Freetown-Sierra Leone, 2012 800 OCB activities were focused in the Douentza 700 OPD consultations were performed, where 28% of patients were children under five years of age, and the main pathology seen was malaria. The IPD, which had 12 beds, 2,6 500 400 1,6 258 300 2,5 422 1,6 1,5 200 100 3,0 602 428 2,0 2,0 1,5 271 0,6 78 1,0 0,4 0,2 0,4 99 0 0,5 0,0 wk28 wk29 wk30 wk31 wk32 wk33 wk34 wk35 wk36 wk37 wk38 Epidemiological weeks had a total of 111 admissions with a mortality rate of 3%. There were 240 primary antenatal 3,5 655 653 600 4,0 CFR Even in those areas, the cases were sporadic ted to the outbreak response. UNICEF and and spread apart, well within the capacities WHO were tangentially involved, but did not of the primary health care units (PHUs). Thus contribute concretely. In week 33, the presi- the intervention in Port Loko was limited to a dent declared a National Emergency, and the donation of Eprep stock, and a short training UK’s Department for International Develop- on cholera preparedness for the District ment (DFID) released two million GBP in week 2.2.3. Cholera intervention – Sierra Leone Health Management Team. 34. This led to a much larger involvement from Sierra Leone has had at least 10 document- MSF was on the alert for the second cholera consultations and 196 follow-ups, 38 postnatal consultations, 11 family planning consultations, and 96 deliveries with 94 live births. Nutrition activities, which started late in the year, saw 52 admissions. ed cholera outbreaks since the seventh world pandemic hit the African continent in the 1970s. Outbreaks often occur during the heavy rains (from May to October), which cause flooding and contamination of water sources. The disease is endemic in the border between Guinea and Sierra Leone, where the coastal swamp guarantees a good environment for the survival of the Vibrio cholera during non-epidemic periods. The first signs of a diarrheal disease outbreak in the country appeared in Freetown during the latter half of 2011. A cholera outbreak was officially declared for Port Loko and Kambia Districts on February 27th 2012. An OCB emergency team arrived in the country on week eight to perform an assessment and intervene if needed. The assessment of Port Loko revealed a gross overestimation of the number of cholera cases. The true cholera outbreak declared in 2012, and was active in the Cholera Task Force meetings at the Freetown level. The first suspected cases of cholera in Freetown were detected in week 25, and V. cholera was confirmed by the MoH Central Laboratory in week 28. Over the course of the intervention (week 28-39), MSF treated 47% of all the reported cases of cholera in the Western Area. At the peak of the outbreak, during weeks 31-35, 56.6% of all the patients were being treated at MSF structures (fig. 1). The case fatality rate (CFR) followed the usual trend in a cholera intervention. It was high at the beginning because the local staff were inexperienced and were probably overwhelmed by the number of cases. The CFR gradually dropped to acceptable levels, only to increase again slightly (two deaths) at the end of the intervention (fig. 2). 23 last three months of the year. In total, 4,760 Cases 811 different actors, and the creation of more task forces (Cholera Coordination Command Centre, Presidential Task Force on Cholera). There was a widespread call for funds from the government, the WHO and several NGOs, based on what has turned out to be an overestimation of the predicted number of cases. MSF remained the sole non-governmental actor in case management in Freetown until the arrival of Save the Children in week 36, who concentrated on Oral Rehydration Solution (ORS) points and supporting Connaught Hospital. With the release in funds, other water, sanitation, and hygiene (WaSH) actors 08. emergency unit three first level health structures) during the 3,3 758 joined ACF in community WaSH activities (bucket chlorination, HP, distribution of household water treatment kits). Outside of Freetown, many NGOs started becoming involved in case management, health promotion and WaSH activities, though the degrees of operationality varied. The presence of cases were probably concentrated in com- During the first month of the Freetown out- these other actors in almost all the districts munities along the coast and the border with break, the MoH, MSF and Action Contre la led OCB to concentrate its activities in Free- Kambia. Faim (ACF) were the only actors fully commit- town and Bo. MEDICAL ACTIVITY REPORT 2012 area (one second level health structure and 3,8 Case Fatality Rate (CFR) 900 hospital (mainly with medicines and HR), Number of cases In 2012, after one month supporting the Gao The nationwide response was initially coordinated by the Directorate of Disease Prevention and Control (DPC)-led Cholera Task Force, but coordination was passed in week 34 to the Cholera Coordination Command Centre, chaired jointly by the DPC and WHO. UNICEF provided the majority of the case management supplies outside of MSF structures, which they distributed through the MoH’s Central Medical Stores. 2.3. Emergency preparedness Eprep training was performed throughout the year in several countries, most notably in India. Additionally, an “assessment training” was done for the regional network in Asia (Hong Kong). The E-Unit continued to support the ongoing Eprep training in South Lebanon. In South Sudan, following possible scenarios of conflict, the E-Unit completed an Eprep for war wounded in Juba. In Sierra Leone after the cholera intervention, an Eprep team was left to cover the needs in the region. In Mali and Mauritania, Epreps were done to cover the possible scenarios of war wounded and cholera. 3. Human resources and training - The VHF full kit is ready to be sent on re- The E-Unit has three permanent emergency - An IT kit was finalised, and will be pro- coordinators and three permanent support staff (HR, logistics/supply and finance). Increased support was required in 2012 for the Syria and South Sudan interventions (emergency coordinator and HR/Finance support). The number of field emergency coordinators (medical and non-medical) remained at around 15 throughout the year . There were more than 350 departures under quest. duced. Two units are in stock. - A hospital electricity kit was finalised, produced, and is in stock. - An energy kit was finalised, production is ongoing, and it will be in stock by the end of 2013. - The development of the boat kit is ongoing and is to be finalised in 2013. E-Unit interventions (from the first of January - The mobile surgery/anaesthesia kit list is to the end of October). The main issue during completed, but must still be checked and 2012 was the lack of experienced staff for HR allocated to work on the production of the Sahel interventions (only non-European a prototype. It is to be finalised in 2013. passports were allowed for security reasons). - The mobile HP Kit was finalised, produc- Another issue was the high turnover in the tion is ongoing, and will soon be in stock in intervention in Maban (fatigue and sickness the emergency unit. during the first two months of the Batil intervention). 4. New developments and innovations New developments in 2012 included: - A telecom kit was finalised, but not yet produced. - The simplification of the protocols to accommodate the low level of the local staff in the Sahel has been completed for hygiene and women’s health. - External trainings were conducted of Medical Focal Persons (MFP) by a Mobile Implementation Officer (MIO) for paediatric issues during the Sahel intervention, and 24 the use of the E-learning was implemented for nutrition training. 5. Looking back and ahead Lessons learned for 2012 A number of specific lessons were drawn from field interventions: - The Eprep training and implementation support continued to show its added value in the field for emergency interventions. An added value is also clear in countries where a conflict scenario is highly possible (as in South Sudan). - The organisation and centralisation of documentation, planned the previous year, was not realised – the optimal way forward will be further considered in 2013. 08. emergency unit - In order to continue to improve security, training and improvement of the tools of the emergency field coordinators is required. - Operational research is possible during emergencies (as was done in Maban), but it must be taken into account that this requires time. Thus, operational research is good for innovation, but not for the emergency intervention in itself. - The intervention in Maban was started late by the E-Unit. More discussion is needed within the emergency cell and by the direction to understand how to better prepare for these kinds of needs. - Concerning communication, there was a good follow up by the communication officers during emergencies throughout the year MEDICAL ACTIVITY REPORT 2012 and there was valuable flexibility from both sides on media needs and a general capability to cover this. However, the capacity of the E-Unit capacity to provide data, testimonies and operation updates for communication needs to be improved. Prospects for 2013 - The training/support for Eprep will be continued, in particular in contexts where emergency scenarios may be anticipated. - The collaborations with external specialists (Orthopaedist International Association, Renal Disaster Relief Task Force, Handicap International, Disaster Epidemiology Centre) will be continued and contacts have been made with the International Spinal Cord Society. - The ongoing training for the installation of the modular field hospital (MFH) will be continued. Scenarios for use of the MFH and logistic adaptation of the supplies (priorities and simplification of delivery) still need to be finalised. - The mobile surgery/anaesthesia kit will be finalised. - The development of protocols for burn care within the Medical Department will be followed up and the possibility for a kit for burn care in emergency interventions will be examined. - The collaboration with the Pool d’Urgence Congo (PUC) will be continued. - Continue the close interaction with the Rio Office (Brazil) in terms of HR (2 positions open for Emergency coordination in Rio) and support of the general overview on emergency assessment. - The level of 10-15 mobile team members will be maintained throughout 2013. - The preparation of the E-coordinators on security and risk analysis management will be continued. - HR will identify an African expat for a coordination position and mentor/prepare them. - Better mapping possibilities will be evaluated and put in place in emergencies . - Proper media briefing and media training to all the E-Unit staff need to be provided. - New satellite devices and technologies (e.g. geolocalisation) are being explored. - The contents of the emergency stock need to be reassessed with the revision of scenarios and protocols. - An assessment of new modes of emergency transport needs to be performed. - New telecom devices such as the telecom kit will be deployed, and research will be conducted in this area. 25 - An assessment with the technical department of new kinds of shelters (e.g., Delta Wood) will be performed. - The “Emergency Boat” will be finalised. MEDICAL ACTIVITY REPORT 2012 08. emergency unit - The development of Extranet MSF Supply for the Emergency Pool will be continued. MSF MEdical Department OCB Epidemiology Epicentre 1. Overview Epicentre epidemiological studies aim at providing MSF with practical evidence to improve its interventions and medical care in general. Results may also be used to support advocacy in the scientific community or with local and national authorities. The Epicentre scientific team is composed of epidemiologists and statisticians. Two epidemiologists are integrated into the OCB medical department (in the Operational Research and Disease Control Units), in order to enhance communication, facilitate new ideas to emerge and allow research projects to be implemented. 2. Activities 2.1. Research in emergency settings Epicentre epidemiologists participated in several OCB field interventions in 2012 (table 26 1). The compilation of the medical data that tion. The Department of Clinical Research pact of a pneumococcal vaccine (PCV) mass focuses specifically on HIV/AIDS, tuberculo- vaccination (target population: birth to 14 sis, malaria and neglected diseases. During years) with administration of reduced dosag- 2012, OCB collaborated in a number of es among infants. This strategy is expected these research activities. to achieve a rapid reduction in transmission 2.2.1. Vaccine preventable diseases 09. Epidemiology/Epicentre gencies and settings where routine vaccina- started in 2011 for all of the MSF projects lo- In early 2010, a surveillance system was put tion is failing. In 2012, a trial site was identi- cated in the Horn of Africa continued until in place in Niger in the Maradi region and in fied in southwestern Uganda. The study week 10 in 2012. These data were updated Niamey, in order to assess the burden of ro- planning has been progressing well, with the and shared with all Operational Centres on a tavirus and to provide a profile of diarrhoeal objective of implementing this trial by the end weekly basis. In March 2012, Epicentre col- disease in children less than five years of age. of 2013. lected and analysed spatial data to guide the During the two first years of surveillance (up until March 2012), 10,600 children were in- In 2011, Epicentre continued its ongoing col- OCB response to an outbreak of typhoid fever ongoing in Harare, Zimbabwe. In July, cluded in the study and 30% were found to Epicentre investigated and mapped a chol- be positive for rotavirus. The G2P[4] geno- era outbreak in Freetown, Sierra Leone. Also, type was predominant during the first year Epicentre supported OCB interventions in and there was a complete switch to G12P[8] Batil refugee camp, South Sudan, by con- during the second year. Publications are in ducting a nutrition and retrospective mortality preparation. The surveillance is now ongoing survey, and reinforcing the surveillance sys- in a subgroup of sentinel sites, with a more tem in place during the hepatitis E outbreak. important focus on the links between rotavirus and malnutrition. These data provide an 2.2. Summary of other research conducted in 2012 important baseline prior to introduction of a The key research areas for the Department of The deployment of new and under-utilized Epidemiology and Population Health (within vaccines in crisis settings is recognized as a Epicentre) are vaccine-preventable diseases, top priority for MSF. In this vein, MSF plans to diarrhoeal diseases, mental health, and nutri- conduct a trial aimed at investigating the im- laboration with OCB in responding to measles outbreaks against the backdrop of a changing epidemiological profile for measles. A publication on the lessons and challenges for measles control from the unexpected 2010 large outbreak in Malawi was accepted for publication in 2012 (Minetti et al, Emerg Infect Dis, 2013). 2.2.2. Nutrition Several scientific studies investigating the rotavirus vaccine. preventive distribution of Ready-to-Use Supplementary food (RUSF) to children in Niger, as well as on the intra-household use and acceptability of RUSF, were completed and published this year (Grellety et al, PLoS One, 2012; Cohuet et al, Appetite 2012). Epicentre conducted a secondary analysis of Table 1: Epicentre/OCB field interventions in 2012 MEDICAL ACTIVITY REPORT 2012 and disease burden, critical for acute emer- Country/project Intervention Topic Horn of Africa Surveillance system and weekly data compilation of all sections Complex emergency Zimbabwe Outbreak investigation: mapping Typhoid Haiti Harmonization of the intersection surveillance system Cholera Sierra Leone Outbreak investigation: mapping Cholera South Sudan Survey Nutrition and mortality South Sudan Outbreak investigation and case-cohort study Hepatitis E 204 MSF nutritional surveys, including 39 surveys from OCB. The aim was to describe the relationship between different indices of prevalence of global and severe acute malnutrition (including mid-upper-arm circumference and weight-for-height). The final report was sent to the Nutrition Working Group for review in October 2012 and further work is planned for 2013. sis and the final report are expected in 2013. 2.4. Niger research base During 2012, OCB continued to support the Epicentre research base in Niger. The studies patients treated in MSF HIV programmes. The study examining the field efficacy of in progress included an ambitious project The database came from various MSF Afri- ACTs (artesunate-amodiaquine, dihydroarte- conducted in partnership with the World can and Asian HIV/AIDS projects, including misinin-piperaquine and artemether-lume- Food Program (WFP), aimed at comparing those from OCB. An article is in preparation. fantrine combination therapies) for the treat- different food distribution strategies to pre- ment of uncomplicated malaria in children vent malnutrition. Other studies focused on i) aged 6 to 59 months entered in a pilot phase the burden of rotavirus (cf. §2.2.1.), ii) the in Maradi (Niger) in 2012. Inclusions will start transcultural validation of a screening tool for in 2013 and will last for one year. mental health distress in children from 3 to 6 Mbongolwane (Eshowe, Uthungulu District, The protocol of a trial aiming to compare the year-old, iii) support to epidemiologic and Kwazulu Natal, South Africa). In 2012, the efficacy of artesunate amodiaquine and ar- laboratory surveillance (including meningitis study protocol was submitted to local and tesunate lumefantrine fixed combinations in and influenza), iv) a preliminary study on the international ethics committees. The study malnourished children was delayed in 2012 molecular resistance and potential use of will start in 2013, as soon as official authori- but progress is expected in 2013. ACT (sulfadoxine-pyrimethamine) for sea- Epicentre plans to conduct a populationbased study to assess the HIV prevalence and incidence, and the programme coverage in support of the scaling-up OCB project in sations are obtained, and will last approxi- sonal malaria chemoprevention in children, mately three months. When repeated over 2.2.5. Miscellaneous time, such a study allows the monitoring of The laboratory working group, with the sup- the dynamics of an HIV epidemic under real port of Epicentre, is developing a study pro- conditions. tocol for a laboratory-based phase 2 evalua- Supported by Epicentre, an MSF intersec- tion of a handheld creatinin analyzer (Nova tional study to evaluate the performance of new and currently used rapid diagnostic tests for HIV in five African countries started StatSensor® XpressTM Creatinine), which seems suitable for MSF settings. This evaluation is planned in collaboration with the Uni- as well as v) the field efficacy of ACTs (artesunate-amodiaquine, dihydroartemisinin-piperaquine and artemether-lumefantrine combination therapies) for the treatment of uncomplicated malaria in children aged 6 to 59 months. 2.5. Miscellaneous Members of Epicentre were involved in pre- in 2011. One OCB (Conakry, Guinea) site versity Medical Center, Utrecht, Netherlands. was included in this multicentric study. The The results of the evaluation of a rapid test for inclusions were finished in 2012 in three the diagnosis of cholera in the absence of a sites, including the Guinea site where all pos- gold standard have been published (Page et itive and negative specimens showed con- al, PLoS One, 2012) as well as results on the cordant results. The study is ongoing in two early prediction of treatment efficacy in sec- other sites. Final results are expected for ond-stage Gambiense human African trypa- 2013. nosomiasis (Priotto et al, PLoS Negl Trop Dis, Finally, the yearly “FUCHIA bulletins” were re- 2012). in Precarious Situations (PSP) courses and 2.3. FUCHIA updates courses which were attended by staff from all leased, providing a standardised descriptive analysis of HIV-infected patient outcomes for all OCB HIV projects, both by project and The last FUCHIA version (1.7.1) was finally globally. released in November 2012. This version incorporates the developments decided on in 2.2.4. Malaria 2011. It includes the Prevention of Mother- The study on the time required for three ma- To-Child Transmission (PMTCT) report in line laria rapid diagnostic tests (RDTs) to become negative after successful treatment in children under five years of age was completed in the site of Kazo, Mbarara district, Uganda (high malaria transmission, 212 patients recruited as per protocol). Results were presented in May 2012. In the site of Kakiika with the World Health Organisation (WHO) recommendations, and an updated user guide in English and French. The FUCHIA helpdesk continued to provide regular technical support to all projects where a FUCHIA monitoring system was implemented during 2011. senting and participating in internal (including working groups) and international meetings on the different themes discussed in §2.2 27 analyses on the tuberculosis outcomes of will be completed in early 2013. Data analy- and 2.1. 3. Training During 2012, Epicentre ran two Populations two Responding to Epidemics (REPEPI) MSF sections including OCB. The PSP course that took place in Frascati, Rome, was run by OCB. In 2012, Epicentre started reviewing the content of the PSP, taking into account the recommendations of the global PSP evaluation of 2011. OCB staff also attended a “Training of Trainers “ organized by Epicentre in Paris. OCB ran a “Responding to emergencies” course for OCB regional staff in Manila, the Philippines. Finally, Epicentre provided support to the “WatSan in emergencies” training organised by OCB in 09. Epidemiology/Epicentre In 2012, Epicentre conducted multi-centric (low malaria transmission), the recruitment Brussels and during the Nutrition and Vaccination training (“Nut-Vacci”). MEDICAL ACTIVITY REPORT 2012 2.2.3. HIV 4. Looking back and ahead Lessons learned for 2012 One of the main challenges in 2012 was to ensure better dissemination of study results to the OCB Operations and Medical departments. Towards that objective, several meetings were organised in the offices of OCB during which Epicentre epidemiologists presented the results of their recent studies on rotavirus, nutrition, measles, typhoid fever as well as on a new framework for use of vaccination during emergencies. These meetings appeared useful and well appreciated. In 2012, Epicentre also extended its collaboration with OCB to the field of HIV/AIDS research. Prospects for 2013 In 2013, Epicentre aims to continue to organise meetings within OCB in order to ensure the dissemination of recent study results to the Medical and Operations departments. Epicentre also plans to organize two PSP courses with a reviewed content based on the recommendations of the 2011 evaluation. And, as usual, Epicentre will concentrate efforts to improve its interaction, MEDICAL ACTIVITY REPORT 2012 09. Epidemiology/Epicentre 28 communication and collaboration with OCB partners both in the field and at headquarters. MSF MEdical Department OCB Evaluation Unit 1. Overview The Stockholm Evaluation Unit (SEU) was established as a pilot project in 2010 with the objective to institutionalise evaluations within OCB and standardise the evaluation process. Following the pilot phase, the project has continued in 2012 as the SEU, under the direct responsibility of MSF Sweden. The unit aims to provide a credible capacity to manage evaluations on behalf of OCB and other sections and to contribute to developing a methodology that can help to measure the medical humanitarian impact of MSF. More than twenty evaluations and reviews were completed by the SEU and they are available throughout the movement alongside those managed by other sections. Together, they provide a useful source of information which can help inform future decisions and choices. During 2012, the SEU managed three evaluations or reviews as well as supporting two others (one for the international office), finalising two from 2011 and planning two for 2013. The three direct evaluations performed in 2012 were : 1) a planned evaluation on behalf of a donor; 2) a review of a training initiative; and 3) a routine evaluation of a largescale emergency intervention (table 1, Annex). formalised their collaboration with a view to since there are only a few evaluations be- share findings, amplify learning, and avoid ing carried out. As a consequence, many duplications and inefficiencies. The group members of the pool are not available worked together on a number of initiatives when needed. including training, the inter-sectional evaluation day and evaluations on request of the international platforms. 4. Human resources and training -The international pool of evaluators has been further reinforced during the year 3. Innovations and collaborations with a course held in April for 20 new pool In 2012 the four evaluation entities within different profiles. However, at any one MSF (Paris, Athens, Vienna, and Stockholm) time, only a few members are at work, members. The international pool consists of more than 200 potential candidates with - All evaluations carried out in 2012 were carried out by consultants with an MSF background. Despite slightly higher financial costs, the use of consultants has proved itself to be more efficient and effective in the long run. 29 2. Programme activities - Despite planning additional capacity within the unit in 2012, the plan did not develop due to the last-minute withdrawal of the candidate chosen for the position of Evaluation Officer. 5. Looking back and ahead - Following the high workload of 2011 and the subsequent (reported) lack of quality, expectations were reduced for 2012: only four to six reviews or evaluations were planned. However, this lower target was still not met, in part due to the number of requests which was slightly lower than expected, and in part because of challenges associated with workload bottlenecks due to the annual planning cycle. - The (perceived lack of) usefulness of the evaluations remained one of the major challenges for the unit. The process invariably 10. Evaluation unit Lessons learned for 2012 failed to produce the expected “new” information, leaving stakeholders feeling that the process had not delivered results. Despite this, In the majority of cases, recommendations were either implemented or reflected changes already made. In the small number of cases where they were not, recommendations provided a useful orientation for discussion and debate. MEDICAL ACTIVITY REPORT 2012 the process itself still proved to be useful, offering a formal moment of reflection and providing a tool for incremental learning. Prospects for 2013 - With between eight to ten evaluations and reviews proposed for the coming year, the output of 2013 will likely pick up again after the relatively limited outputs of 2012. Also, the issue of the planning cycle will be overcome, with an additional focus on planning activities for the coming 18 months and beyond. - The SEU will continue to invest in and support the intersectional training course for evaluators, with a view to developing a basic level of skills and knowledge for all those involved in commissioning and using evaluations as part of operational management. - Investment in the evaluator pool will be reduced in favour of using “external” evaluators on a consultancy basis and pairing them with “internal” MSF evaluators. The use of external consultants should help improve the objectivity of the evaluation process and reduce the potential bias in recommendations and results. - Increased collaboration will be explored with other units of OCB, in order to capitalise on experience and expertise as well as amplify the learning process and maintain efficiency. International collaboration will be further developed and strengthened, and renewing the collaborations with other operational centres will be a priority. - Streamlining systems for sharing and dissemination will be a continued priority, with an additional focus on the follow-up and use of results and recommendations. Broader, long-term learning initiatives will also be developed. - ”Making evaluations work for us” will be the focus for 2013, particularly with regards to methodology and approach. There is a need MEDICAL ACTIVITY REPORT 2012 10. Evaluation unit 30 to look beyond the evaluation of output towards a more robust measurement of the impact on the medical humanitarian intervention. MSF MEdical Department OCB Health Informatics 1. Overview Improving the data management process at field level remained a core activity. Unfortunately, even though the policy of briefings at OCB headquarters (HQ) changed during 2012, some epidemiologists went to the field without passing by HQ. However, some countries (Burundi, DRC) have been visited by the OCB Data Officer to support and train the field staff with the goal of improving the overall data quality. Within OCB, two main tools exist for the standardised monitoring and reporting of general medical programme data. The most frequently used is the Epicentre tool for data involving outpatient and inpatient departments and gynaecology/obstetrics services (OPD/IPD/Gynobs tools). More recently, the Medical Information Network for Operational Support (MINOS) was introduced – this is a system designed in-house for the collection, storage, transmission, analysis, and reporting of medical service data. This system currently handles the data generated by the most common MSF services: OPD, IPD, sexual and reproductive health services, and therapeutic feeding centres. The Epicentre tools were used in 12 missions, which represents 86% of the missions which were supposed to implement the tools (14). MINOS was expanded from two missions to five, and eight projects reported their 2012 data through MINOS during the annual data collection. For all other missions/projects, the annual data was collected through the International Typology data request, which was again synchronised with all other medical data requests to the field. 2. OCB routine data tools 2.1. Epicentre tools Of the 73 OCB projects reporting medical The use of the Epitools remained relatively data, eight were using MINOS as main data stable, with 12 out of 14 missions (86%) reporting tool by the end of 2012 and 21 which were supposed to implement the were using the Epicentre tools (fig. 1). The Epitools actually using them, vs. the 88% in projects using neither of the two were mainly 2011. Their use was well accepted in the vertical projects (HIV/Tuberculosis (TB), sexu- field. ventions – refugee care in Maban (South Sudan) and Mali – also used MINOS and the Epicentre tools. Among the 1,816,100 general OPD consultations (i.e. disregarding ante- and postnatal care and family planning consultations), 61% were reported through Over the course of 2012, the recurrent chal- Other 21% MINOS 19% Epitools 60% lenge of the Epicentre tools of their inability to aggregate data across different tools was finally addressed: a sum-up tool was generatEpitools ed which can aggregate OPD/IPD/GynObs Figure 1: Main data tools per OCB project, end 2012 (n=73) the Epicentre tools and 18% through MINOS MINOS Figure 3: OCB data reporting tool for IPD admissions, 2012 (n=73,210) Other 8% Epitools 29% (fig. 2). Following approximately the same Other MINOS 11% trend, among the 73,210 general IPD admissions (i.e. disregarding admissions to inpatient therapeutic feeding centres (ITFC) and maternity admissions), 81% were reported through the Epicentre tools and 11% through MINOS (fig. 3). Other 60% MINOS 11% Epitools MINOS Other 11. health informatics ventions; two of the major emergency inter- Figure 2: OCB data reporting tool for OPD consultations, 2012 (n=1,816,100) Epitools 81% Epitools MINOS Other MEDICAL ACTIVITY REPORT 2012 al violence, etc.) and minor emergency inter- 31 Emergencies, vertical projects and smaller-sized projects tended to collect and report data through customised databases. Additionally, a number of dedicated databases on specific activities (sexual violence, neonatology, etc.) were implemented in a number of projects. data across up to 20 different datasets, which guage for the user interface. This will also al- face; develop a fuller change management will save a large amount of manual work of low for the expansion of MINOS into other strategy; and increase resources devoted aggregation. Additionally, the quality of the francophone countries in 2013. to the project. These recommendations Epicentre tools was further improved by al- One of the limitations of MINOS often cited in lowing them to collect the data for years of 53 weeks, which was previously impossible. NOS data (cf. §2.2.), provided the basis for tools have provided graphical and tabular Dedicated databases for the monitoring of most of the data analyses presented in this display of several indicators simultaneously, vertical HIV/TB projects and specific activi- Medical Activity Report, most notably the which has been of great value to the field. To ties such as mental health, nutrition, surgery, sections on Malaria, Medical Structures, add this capacity to MINOS, the business in- etc. are discussed in the relevant sections. Of Paediatric Care, Sexual and Reproductive telligence reporting tool (BIRT) was integrat- note, several new databases collecting data Health and Vaccination. ed into the software. This will allow simulta- at the individual level and designed at HQ neous display of a previously defined were introduced/piloted over the course of selection of indicators. Report formats have 2012: been designed for therapeutic feeding pro- - A database on sexual and gender-based grammes, antenatal care, and ambulatory violence, implemented in Masisi and Nian- As stated above, MINOS handles the aggre- primary care. This capacity is now a part of gara (DRC), Nasr City (Egypt), and Kibera gated data of most standard MSF services. version 2.0 of the software - though a fuller (Kenya). For these services, MINOS produces and range of report formats will be needed for this displays the standard project monitoring and capacity to be fully exploited. epidemiologic surveillance indicators. These - A neonatal database, implemented in Ahmad Shah Baba, Lashkar-Gah and Khost indicators show the use of MSF medical ser- 2.2.4. Evaluation (Afghanistan); Masisi (DRC); Dakoro and vices by the beneficiaries, the quality of those During 2012, an invited external evaluation of services, and the trends of the occurrence of MINOS was carried out by the Centres for Referral Centre (GRC) in Bo (Sierra Leone). diseases of operational interest. The scope Disease Control (CDC) Public Health Infor- of MINOS is the production of these indica- matics Fellowship Program. After several tel- tors. econferences and reviewing available docu- Project data requires exportation from field da- mentation tabases, transmission to the capital and HQ, conducted a site visit over the course of one and importation into the HQ databases. Auto- week to interview staff at OCB HQ. The eval- mation of this manual process has been post- uators’ conclusions were that: poned to allow concentration of developer re- - MINOS has great potential as a key sys- sources on higher priority tasks. Nevertheless, tem in the emerging information system the process is simple enough that field data enterprise within OCB. It also has the po- are made quickly available to HQ and mission tential to be a major force in the field of coordination staff. public health and disaster informatics. 2.2.2. Implementation At the beginning of 2012, MINOS was only implemented in one project in Pakistan and in two projects in South Sudan. A Mobile Implementation Officer (MIO) was engaged to facilitate MINOS implementation in the field. Over the course of the year, MINOS was expanded in South Sudan and Pakistan to on MINOS two evaluators Guidan Roumdji (Niger); and the Gondama - An Emergency Room database (cf. Emergency Medicine section, §2.3.1.), piloted in Kunduz (Afghanistan), Martissant and Tabarre (Haiti), Karachi (Pakistan), the GRC (Sierra Leone), and Burao (Somaliland). 2.4. Typology All routine programme data not reported through the Epicentre tools, MINOS or a dedicated database were collected directly in the annual Typology data compilation. The Typology represents an initiative by the MSF International Office that collects a set of inter- - It however needs more investment in its sectionally agreed indicators, aggregated per development and field implementation to year. In OCB, a number of important pro- drive its use, and clearly demonstrate its gramme indicators are integrated into the an- operational and organisational value. nual Typology data collection, in order to - The use of good quality information (that streamline the process and not overburden MINOS can provide) by OCB and the MSF the field with multiple data requests. For movement supports its culture of open- most missions this process went smoothly – ness and accountability. however, some vertical projects (notably the cover the remaining projects. MINOS was - Balancing the varying demands of stake- also initiated in Somaliland, Egypt, and DRC. holders and delivering value across the OCB represents the next phase in the life- MEDICAL ACTIVITY REPORT 2012 2.3. Other data tools how this indicator might be displayed. Past 2.2.1. MINOS background 32 at a time - allowing the user great flexibility in for 2013. The Epicentre tools, supplemented with MI- 2.2. MINOS 11. health informatics 2012 was its design to deliver one indicator have been incorporated into the planning 2.2.3. New developments cycle of MINOS, and institutional support A necessary expansion for MINOS imple- is necessary for its success. mentation in DRC was adding the ability to - Recommendations were to: add software select either French or English as the lan- testing capacity; improve the user inter- HIV projects) and missions which underwent a transition of data system over the course of the year experienced some difficulties in supplying complete data. As a consequence, minor differences may occur between different versions of the annual data. 3. Looking back and ahead Lessons learned for 2012 - The implementation of the Epicentre tools has been well accepted in the field, but the quality of data needs still to be improved. Field staff need to be encouraged to improve quality of data collection and, in particular, to use these data to monitor their respective projects. Data management should not be perceived as an exercise in sending data to HQ. - The overhaul of the Epicentre tools in 2012 answered to the needs expressed in the field, allowing aggregation of data from multiple tools of a single project and collection of data for the years with 53 weeks. - The installation of MINOS in the emergency intervention in Maban (South Sudan) was not without complications. The high rate of turnover in this project rapidly replaced the experienced users who were trained at implementation, and newcomers did not have experience with this novel tool, nor was there a sufficient handover. The ensuing burden of learning a new tool added to the already high workload on the team in the field. It may thus be better to postpone deployment to emergency contexts until the expanded use in more routine missions has created a “MINOS culture”. - Turnover as a cause of loss of competence is not limited to emergency projects. The implementation procedures used in 2012 focused on the training of data managers and a limited set of supervisors. In a couple of contexts, the departure of these individuals caused a significant decline in the ability of the mission to make use of MINOS. Future implementation will need to target a broader user base as well as assuring a local mechanism of training that ensures continuity of competence. - The transition between data management tools is easiest at the change of calendar years. The end of 2012 was no exception, with both DRC and Afghanistan requesting MINOS implementation at that time. This problem can be avoided in the future by better planning and facilitating mid-year transitions - e.g. by allowing for the migration of data collected earlier in the year. - A number of bugs in MINOS were reported over 2012. This is an understandable consequence of having to deploy software before it had been fully tested. The discovery of bugs and the need for testing has been taking into account in the planning for 2013. - The quality of data depends on the good links between the medical department, the medical polyvalents, the medical coordinators and the staff in the field. When everybody in the network understands the importance of data for project monitoring, data collection will 33 become easier and the quality of the collected data is likely to improve. This will continue to be our challenge in the future. Prospects for 2013 - In 2013, emphasis will continue to be placed on the use of the Epicentre tools in settings where MINOS is not available. Briefings of new medical polyvalents, expatriates going to the field, and during trainings and field visits will be conducted as usual. - Discussions will be held on the possibility for regional data collection trainings of epidemiologists and database technicians in the field, to understand what the data quality problems are and how to solve them. - MINOS has been selected as one of the ten projects in OCB to be organised and supported by standardised project management methodology. This will involve the creation of a steering committee and more precise planning. - In 2013 a data integration officer will be added to the MINOS team. This person will be charged with: - Software testing and bug description. - Creation of standardized BIRT reports in collaboration with subject matter experts in the medical department and operations managers. - Integration of past data collected with legacy software into MINOS. - Set up and fine-tuning of an anomaly detection system to provide data validation on entry and proactive detection of epidemics. - Field implementation of MINOS will be continued: Afghanistan is the first mission scheduled for 2013. From there, additional missions will be added, starting with those whose medical services are best matched to the current capabilities of MINOS. 11. health informatics - Project management, overseeing the timely advance on MINOS deliverables. - As experience with the Maban project in South Sudan illustrated, having a well informed and trained user base is critical for good system course began in 2012, but will need to expand. Additionally, other components of change management will need to be added: user guides, self-training videos, and a more robust communication programme. - The most important feature to be added to MINOS is the handling of individual data. Some service types require indicators that cannot be calculated on the basis of aggregated data, e.g. those with longitudinal patient follow-up such as HIV/TB. Work on developing this capacity is scheduled for 2013, and it is hoped that it will be ready by the end of the year. - At the level of specific databases, the development and use of data collection and monitoring tools in emergencies and conflict settings will be explored, with the goal of improving both the routine data monitoring and operational research in this domain. MEDICAL ACTIVITY REPORT 2012 acceptance and performance. The integration of MINOS into training programmes such as the Management of Health Systems (MHS) MSF MEdical Department OCB Health Promotion and Socio-Anthropology 1. Overview Health Promotion (HP) activities continued to be well integrated into both existing and new projects as well as emergency interventions. 2012 was a busy year that saw several changes in the work load distribution. Both the position of support to the referent and the Mobile Implementation Officer (MIO) for HIV/tuberculosis (TB) Patient and Community Support have been discontinued. On the other hand, a new position of HIV/TB Patient and Community Support advisor was created within the Southern Africa Medical Unit (SAMU). This position integrates HP and mental health into one global support position (including the educational, social and counselling aspects). The advisor is part of the SAMU unit based in Brussels. In this report, all HP issues related to vertical HIV/TB projects will be presented in the HIV/TB section. Collaboration with other MSF sections (OCBA, OCG) was initiated through a contact group, which allowed the sections to share experiences, practices, and tools while developing a common approach. A “hygiene promotion forum”, composed of different agencies dealing with HP, has also been used to promote collaboration and further contacts. 12. Health Promotion and socio-Anthropology 34 2. Programme Activities 2.1. Health Promotion activities at a project level - example In 2012, HP activities were conducted in 32 4. Research and developments 4.1. Qualitative surveys projects across 17 missions - not including To better understand the socio-cultural con- vertical HIV/TB projects, which are reported texts in which OCB operates, and better sup- The typical workload for the HP/anthropolo- elsewhere (cf. HIV/TB section, §2.9.). These port OCB medical activities, qualitative socio- gy component of an OCB mission is demon- projects included emergency interventions anthropological strated in table 1. In this project, performing (three projects; table 2, Annex) and regular conducted as part of HP activities. Addition- more than 75,000 outpatient consultations projects (29 projects; table 3, Annex). ally, two comprehensive evaluations of the HP 28,446 individuals were reached by HP/anthropological activities. Most of these were activities focusing on Maternal and Child Health and classical HP among the patients of Timergara project. Other, more specific activities were also conducted (such as support to the blood bank), but to a much lesser extent (table 1). 3. Training and Human Resources Number of participants N (%) Maternal Child Health 16,296 (57%) Hygiene Promotion 10,642 (37%) Seasonal Diseases 1,446 (5%) Blood Bank 62 (0.2%) Total 28,446 were routinely are available upon request. - DRC - Masisi: satisfaction survey on the The number of trainings including an HP or medical care provided to the HIV patients socio-anthropology topic has remained con- in Masisi Hospital. stant from last year: - DRC - Kinshasa coordination: satisfaction -Water and Sanitation (WatSan) week in emergencies: module “Health promotion in WatSan and emergency” Table 1: Health promotion activities in Timergara, Pakistan, 2012 surveys component have been conducted. All reports and admitting more than 2,500 inpatients, Health education session MEDICAL ACTIVITY REPORT 2012 2.2 Health Promotion general overview -Reproductive “Health Health promotion regarding their medical care. -Egypt - Abu Elian: Knowledge, Attitude module and Practice (KAP) survey on health-seek- reproductive ing behaviour of women and children un- training: and survey for MSF staff and their beneficiaries health” der five. - Management of Health Services course: -Bangladesh - Kamrangirchar: survey on module on “Medical anthropology and barriers to accessing SRH services for health promotion in OCB” adolescent and young women (15 to 24). - Health Promotion level I training in Brussels: ten day training, open to all sections. - Health Promotion level II training in Brussels: one week training, open to all sections. 4.2. New/revised policies and protocols During 2012, the HP unit was involved in the development of several guidelines and protocols: -Revisions and updates of all HP documents and tools available by medical topic. The Health Promotion Tool Kit is now available on USB key. - Ongoing work on HP messages per topic (sexual and reproductive health, nutrition, etc.). 5. Looking back and ahead Lessons learned for 2012 An HIV/TB Patient and Community Support advisor has been recruited for two years. He will respond to the need for capitalization of field experiences and promotion of innovative patient support approaches, development of training and mentoring on patient support, general and direct field support, and promotion of operational research on patient support. The advisor is part of the SAMU and fully in charge of all vertical HIV/TB projects. All existing health promotion materials and documents have been re-organized and gathered in an “HP tool kit” created to replace the previous two DVDs. This toolkit is now available on USB key, by FTP site, and on a Health Promotion platform on Tukul (workspace accessible upon request). HP participation to the Fifth Emergency Environmental Health Forum held in London provided a good opportunity to create networks and become integrated within the hygiene promotion forum. Participatory activities of this kind are key to developing more interactions with other actors active in the field of HP. Some contacts and exchange with other MSF sections, including OCG and OCBA, led to the creation of a Health Promotion and Anthropology “contact group”. A first meeting was held and further collaboration is anticipated. part of the centralized MSF medical database (MINOS), thus aiding in the standardisation of HP data collection. 35 Standard HP indicators have been developed and disseminated but not yet implemented in all projects. Ideally these indicators should be Prospects for 2013 Efforts to integrate HP activities into different areas of intervention should be maintained, with a special focus on qualitative research and links with other programme components. Qualitative data will continue to be collected routinely on a large scale, and a formal collaboration the Populations in Precarious Situations (PSP) training, and the intersectional workshop on HP and Anthropology. MEDICAL ACTIVITY REPORT 2012 Efforts to maintain links with other section should also be continued through the Contact Group, the integration of HP in 12. Health Promotion and socio-Anthropology with the Operational Research and Analysis and Advocacy Unit will take place in 2013 with two missions: South Sudan and Egypt. MSF MEdical Department OCB HIV/AIDS and Tuberculosis 1. Overview The 2012 scientific environment around HIV and tuberculosis (TB) has been dynamic, with high-level political declarations in line with “the end of AIDS in sight”. Strategies focused on reducing HIV incidence using large-scale “treatment as prevention” combined with other prevention methods have been highlighted as key future interventions. National policies in high burden countries have tried to adapt to more ambitious World Health Organisation (WHO) targets, in large part by increasing the CD4 count initiation threshold to 350 cells/µl and moving out of option A towards B or B + (universal antiretroviral therapy (ART) for all pregnant women regardless of CD4 count) for the prevention of mother-to-child transmission (PMTCT). This progress has continued despite absence of new international funding, with the cancellation of the Global Fund Round 11 and PEPFAR (President’s Emergency Plan For AIDS Relief) reducing its funding levels this year. 36 OCB has managed to navigate this financial ”storm”, which included changes to its internal HIV/TB allocated budget portfolio, adopting more focused strategies and implementing more ambitious targets in several of its vertical programmes (e.g. B + in Malawi and CD4 350 in all other sites). OCB operations have expanded geographically by adopting a “light approach” in several new districts, using supportive rather than substitutive approaches. These strategies have resulted in an ART initiation increase of 25%, including a 20% increase in paediatric initiations. This was accompanied by an increased pace of stavudine phase-out (d4T), switching to a tenofovir (TDF)-containing first line regimen. However, the large investment in vertical programme came at a cost: little progress was made in implementation of the HIV minimal package in non-vertical projects, despite a strong OCB commitment to do so. Regarding TB, integration of HIV/TB activities progressed in several countries, and widespread implementation of the new molecular test for TB, Xpert MTB/Rif, came with detection of drug-resistant TB (DR-TB) everywhere and raised DR-TB treatment questions across a number of OCB projects. 2. Programme activities 13. HIV/AIDS and Tuberculosis 2.1.1. HIV At the end of 2012, OCB was supporting 17 vertical integrated HIV/TB projects in the following 10 countries: India (Mumbai), Guinea (Conakry), DRC (Kinshasa), Mozambique No. of countries 2.1. Introduction MEDICAL ACTIVITY REPORT 2012 roll-out of rapid molecular testing for TB and Figure 1: Number of countries with HIV projects supported by OCB 2004-2012 20 18 16 14 12 10 8 6 4 2 0 15 17 19 drug resistance (Xpert MTB/RIF) across a number of projects. A new vertical TB project 18 14 was launched in the Jebel Awilia area in Khar12 10 10 10 Nsanje, Chikwawa), South Africa (Khayelit- toum with the highest burden of TB, the project will be supporting TB-related activities in five health facilities of the area, focusing on 2004 2005 2006 2007 2008 2009 2010 2011 2012 Year (Mavalane, Tete), Kenya (Kibera), Zimbabwe (Buhera, Gutu, Chikomba), Malawi (Thyolo, toum, Sudan. Located in the area of Khar- TB case detection, treatment of drug sensitive TB, and patient and community support. DR-TB projects in Donetsk, Ukraine and Dire 2.1.2. TB Dawa, Ethiopia launched curative activities, Lesotho In 2012, OCB continued TB-related activities initiating their first cohorts in June and De- (Roma), and Ukraine (Donetsk). The focus in ten vertical TB or HIV/TB projects in India, cember 2012 respectively. continued to be on countries with the highest Guinea, Mozambique, The speed and scale of integration of TB care HIV burden in Southern Africa (fig. 1). The South Africa and Malawi. In addition, in 11 in non-vertical projects in settings with a high very favourable quantitative and qualitative non-vertical projects in settings with a high burden of disease was, however, variable. results of the “light approach” programmes in burden of TB, OCB teams were involved in Considerable progress was observed in a Zimbabwe (Gutu and Chikomba) and Malawi delivering different components of TB care. In number of projects (Chhattisgarh and Mon in (Nsanje and Chikwawa) continued to demon- vertical projects with a high burden of drug- India, Kamrangirchar in Bangladesh, and strate the added value of MSF’s support to resistant tuberculosis (DR-TB), the focus has Imey in Ethiopia), while other projects were kick-start HIV activities and decentralise the been on improved DR-TB case finding and rather slow in integrating the minimum pack- provision of ART in new districts. diagnosis, which was advanced by further age of TB care into their activities. sha, KwaZulu-Natal, Musina), Ukraine, Ehiopia, 2.2.2 TB case finding The proportion of children among newly reg- In 2012, 17 projects reported their TB case- 2.2.1 HIV testing finding data (table 1). A total of 5,960 TB pa- istered TB cases declined in 2012 to 10% (14% in 2011). This is likely due to lack of reporting from several nutritional projects in Over the last year, HIV testing and counsel- tients were registered in OCB-supported pro- ling (HTC) has been increasingly supported grammes during the year, about 9% of whom by partners (e.g. Ministries of Health and were retreatment cases. The decrease com- other international NGOs) resulting in an pared to 2011 data is due to several factors: overall sharp decline of the facility-based discontinuation of reporting drug sensitive TB Only 29 children, in contact with active TB testing strategy (fig. 2). As a result, only five of (DS-TB) cases from Khayelitsha project cases, were reported to have been offered the ten OCB vertical projects are supporting (which reported 1,509 cases in 2011, and isoniazid preventive therapy (IPT) in 2012 (67 HTC (Guinea, Kibera, KwaZulu-Natal (KZN), narrowed its focus on DR-TB cases since) in 2011), which is less than 0.5% of the total Musina and Lesotho). The projects in Kibera and Tete (reported 396 cases in 2011), and number of new TB patients registered during and Guinea continue to support facility- missing data from DRC, Niger and Sierra Le- the year, suggesting that tracing and follow- based testing, while Musina, KZN, and Leso- one projects (seven projects reported 1,379 ing up of child contacts needs to be more tho have moved towards a community- cases in 2011). Despite the overall drop in TB systematically addressed and/or reported in based testing strategy. The project in KZN, cases, six projects reported increases in the all projects with TB activities. South Africa, implemented a novel approach number of TB patients registered, including a in community-based testing in 2012, using significant increase in Chhattisgarh (India) mobile and door-to-door testing strategies. project from 71 to 199 cases, Bangladesh In 2012, 75,624 patients were tested, with (from 5 to 27), and KZN (from 502 to 950). 12% found to be positive. Additional new Two projects started registering TB cases in In 2012, 27,396 patients were newly regis- testing strategies, such as oral self-testing, 2012 – Mon (India) with 180 registered cases, tered in HIV care and treatment in OCB-sup- will be introduced in some projects in 2013. and Nsanje (Malawi) with 622 cases. The ported clinics (fig. 3). This decrease since At the programme level, considerable em- largest TB cohorts were reported in South 2011 may be linked to data recording prob- phasis has been placed on ensuring that all Africa, Zimbabwe, and Malawi. lems, as it does not match the observed in- TB patients are tested for HIV and that all Increased access to molecular testing (Xpert pregnant women presenting for antenatal MTB/RIF) in 2012 prompted a change in re- care are tested as part of overall PMTCT ac- porting, and instead of reporting smear posi- tivities. In 2012 64% of all TB patients and tive and smear negative pulmonary TB (PTB) 92% of all pregnant women were tested for cases, projects in 2012 reported “confirmed HIV in MSF supported programmes. pulmonary TB cases” which included smear and Xpert positive. Among new TB cases, TB (EPTB) cases, although slightly increased 75650 in 2012, continues to be lower than expected 75624 in most projects. This further prompts the need for thorough clinical examination of patients with TB symptoms together with ac- 2007 2008 2009 2010 2011 2.3. Patient enrolment 2012 2.3.1. Pre-ART enrolments crease in ART initiation (cf. §2.3.2.). Data reveal that pre-ART retention remains weak but a number of projects have begun to implement some additional strategies, such as isoniazid preventive therapy, which may support pre–ART retention (South Africa, Lesotho, Kenya and Malawi). 2012 curate interpretation of their X-ray images. Figure 3: Number of newly registered HIV patients in OCB programmes by year of entry, 2005-2012 45000 40000 35000 30000 25000 20000 15000 10000 5000 0 39352 28919 37011 29871 30931 34640 25905 27396 2005 2006 2007 2008 2009 2010 2011 2012 Table 1: Tuberculosis case detection in OCB projects, 2008-2012 2008 (23 projects reporting) 2009* (14 projects reporting) 2010 (21 projects reporting) 2011 (22 projects reporting) 2012* (17 projects reporting) Total number of TB cases registered 10,848 4,198 8,741 8,255** 5,960 i. New cases 8,859 3,713 7,641 6,869 5,423 Smear-positive pulmonary 43% 35% 35% 34% 41%*** Smear-negative pulmonary 36% 40% 43% 45% 35% Extra-pulmonary 21% 25% 22% 22% 24% ii. Retreatment cases (% of total) 2,006 (18%) 495 (12%) 1,100 (13%) 884 (11%) 560 (9%) Data were not available from all OCB projects with a TB component in 2009 and 2012; ** One project was able to provide a total (n=502) but not a breakdown by new and retreatment cases; *** Confirmed PTB (sputum smear or Xpert MTB/RIF positive cases) * 13. HIV/AIDS and Tuberculosis However, the proportion of extra-pulmonary 96981 74185 previous years. MEDICAL ACTIVITY REPORT 2012 cases was 41%. 163178 161192 paediatric TB cases had been diagnosed in the average proportion of confirmed PTB Figure 2: HIV testing supported in OCB projects, 2004-2012 180000 160000 140000 120000 100000 80000 60000 40000 20000 0 Niger and Sierra Leone, where most new 37 2.2. Testing for HIV and TB 2.3.2. ART enrolments A total of 29,925 adults and children were initiated on ART in 2012 compared to 22,570 in 2011 (fig. 4). This is to a large extent due to the implementation of B+, the universal implementation of the higher initiation threshold Africa. Malawi significantly increased the the WHO 2010 guidelines recommending number of adults initiated on ART in 2012 initiation of all HIV positive infants under the due to the implementation of PMTCT B+, age of two years on ART regardless of CD4 while the expansion in new adjacent districts counts. In 2012, the South African projects, showed rapid results, mostly in Nsanje and in line with their national guidelines, moved to Gutu (fig. 5). initiate all children under the age of five. It is of 350 cells/µl, and the successful decen- The majority of projects in 2012 were able to tralisation to more clinics in the new projects initiate all new patients on the less toxic TDF- of KZN, Gutu, Chikomba, and Nsanje. based first line regimen, except for Malawi (only pregnant women and individuals with negative side effects were eligible for TDF in Figure 4: ART initiations (adults and children) in OCB projects, 2005-2012 tries are likely to move towards a TDF-based first line regimen in 2013. For those projects 29925 30000 20000 15404 mendation in 2013 based on evidence that earlier ART treatment in these children will help to prevent long term respiratory, cardiologic and neurological problems. 2012), Mozambique, and DRC. These coun- 35000 25000 likely that this will become a general recom- 22570 21492 20018 20443 17318 17159 Figure 6: Paediatric ART initiations in OCB projects, 2005-2012 using the electronic data management sys- 3500 tem FUCHIA, the percentage of patients re- 2500 maining on a d4T-based regimen represent- 2000 10000 ed 12.4% of the cohort, a reduction of 20% 1500 5000 from 2011. 15000 2949 3021 3000 2386 2558 2621 2422 1962 1930 1000 500 0 0 2005 2006 2007 2008 2009 2010 2011 2012 2005 2006 2007 2008 2009 2010 2011 2012 2.3.2.2 Paediatric ART Initiations In 2012, a total of 2,422 children were initi- 2.3.2.1 Adult ART initiations ated on ART in OCB-supported pro- The greatest proportion of adult ART enrol- grammes, an increase since 2011 (fig. 6 & 7). ments in OCB programmes still remains in All OCB supported projects have access to Malawi, Mozambique, Zimbabwe, and South early infant diagnosis and have implemented The increase in paediatric ART initiations does not reflect the adult threshold initiation, as more aggressive PMTCT strategies are supposed to reduce the number of infected children. It is rather a result of the successful decentralisation of paediatric ART initiation in Figure 5: Adult ART initiations by OCB projects, 2011 vs. 2012 38 Mavalane, KZN, Conakry, and Kinshasa as well as the project expansion in Nsanje, in 10000 which a substantial number of children were 2011 2012 9000 8000 enrolled. All OCB projects have by now switched children away from the more toxic 7000 d4T-based first line regimen and all projects 6000 apart from Malawi are able to provide a more 5000 robust lopinavir/ritonavir-based first line regi- 4000 men for PMTCT-exposed positive children. 3000 South Africa as an exception provides a lopi- 2000 navir/ritonavir-based first line regimen for all 1000 children under three. sk ne t Do M um ba i in a us m ba M C Ki hi ko ha sa m Ki ns a be ra u ut Ro on G ak ry sh a Kh M C KZ N bi ur am N ay el it nd a e sa nj ne lo al a yo av Th M 2.4. HIV and TB outcomes 2012 2.4.1 ART outcomes Figure 7: Paediatric ART initiations in OCB projects, 2011 vs. 2012 2.4.1.1 Adult ART outcomes 800 700 The current target for combined death and 2011 2012 600 loss to follow-up (LTFU) is set at less than 15% at 12 months. This equates to a “remaining in 500 care” (RIC) indicator of >85% at 12 months. 400 For projects reporting cohort outcomes, retention in care at 12 months ranged from 64% 300 in the Mumbai project to 95% in the Gutu pro- 200 ject in Zimbabwe (fig. 8). 100 In most of these projects, the rapid imple- 0 ba i um M ne ts k a in us M Do Kh ay e lit sh a a m Ro ba m ko C hi be ra Ki sa Ki ns ha y N ak r on C u KZ ut G nd a bi ne av M ur am M al a nj sa N yo lo e mentation of community-based chronic care Th MEDICAL ACTIVITY REPORT 2012 13. HIV/AIDS and Tuberculosis 0 strategies based on the community groups/ clubs model (cf. §2.9.) are likely to improve Figure 8: Adult Retention In Care at 12 months, for patients initiated in 2011 in OCB projects 100 90%. Musina project is an exception; be- 90 76 73 71 70 60 50 40 30 20 10 due to the timely (within 2 days) defaulter ra e Ki be M av C on ak al an ry N Ro m KZ a sa Ki ns ha el its h G ut u cal community partners at the clinics. The a 0 tracing system that is performed by their lo- ay rates in the Zimbabwean projects are likely 77 70 a bile patients. The amazingly high retention 79 80 Kh specific counselling package for these mo- 86 bi nd given an official transfer letter as part of the 87 lo documented as being LTFU will have been 89 M ur am bwean migrant farm workers, many of those 95 yo cause it is a cross border project for Zimba- % Retention in Care at 12 months increase in the 12 months RIC objective to Th long term retention even more, permitting an high death rate in the Mumbai project is likely because its cohort is a particularly vulnerable second line cohort and often co-infected with TB or MDR-TB, while Kinshasa’s high mortality is due to the enrolment of mostly 40 35 Death LTFU 0 30 26 has been decentralized to the primary care 5 TB treatment outcomes for patients with drug-sensitive (DS) TB were available for 4,010 patients registered during 2011 from eight projects. In five additional projects, TB patients, once diagnosed, were referred to the respective National TB Programmes (NTP) for management without any further 22 4 22 12 9 9 8 sa ur Ki M am ns bi um ha ba i a nd ha its el 39 M Kh M C ay Ki on Ro ak m a ry N be us KZ ra in e a 0 fully, will continue to improve retention rates. 2.4.2. TB outcomes 13 2 23 13 M HIV care nearer to their homes which, hope- 10 34 15 vertical programmes, MSF paediatric ART tings. This means children are able to access 27 20 10 level and is initiated by nurses in most set- 5 2 an that of adults (fig. 10 & 11). In most of the 7 al Paediatric RIC at 12 months is higher than 3 25 av % Dead and LFU very advanced AIDS cases (fig. 9). 2.4.1.2 Paediatric ART outcomes Figure 9: Adult death and LTFU at 12 months for patients initiated in 2011 in OCB projects Figure 10: Paediatric Retention In Care at 12 months for patients initiated in 2011 in OCB projects 120 100 97 100 91 87 85 85 83 77 81 80 65 60 47 40 20 MSF support or involvement. Among prona 13. HIV/AIDS and Tuberculosis M us i a er Ki b e an av al as M C Ki n sh on a kr a y N KZ m ur a M Kh a ye l bi its Ro Th success rate of >85% was achieved in Imey nd a ha m lo yo ut G itive TB cases in 2012, the target treatment a 0 u (89%) and Thyolo (87%). Only one other project, Roma (80%), was close to achieving this target treatment success rate (fig. 12). Death rates exceeding the 10% target were observed in Murambinda (12%), Roma (15%), and Nsanje (11%). Treatment interruption Figure 11: Paediatric death and LTFU at 12 months for patients initiated in 2011 in OCB projects 60 0 Death 50 LTFU 40 rates exceeding 10% were observed in 6 30 53 tended to be higher for patients with smear- 8 ha ns Ki ur M sa a am bi ak on C el ay Kh nd ry ha its ne 6 3 2 2 lo 10 yo 11 Th 11 5 a 13 la av a a KZ N M Murambinda and Kibera. Mortality rates 15 0 er were observed in Chhattisgarh, Conakry, 0 6 15 a Treatment interruption rates exceeding 10% 10 in Kibera with 79% (fig. 14). 8 0 29 us Imey had a success rate ≥ 85%, followed by 20 M new smear-negative and EPTB cases, only Ro m 13). Among projects that had more than 20 Ki b Nsanje (16%) and Chhattisgarh (44%) (fig. MEDICAL ACTIVITY REPORT 2012 jects that had more than 20 new smear-pos- negative and EPTB, due most likely to delays in diagnosis and initiation of TB treatment. Mortality rates exceeded 20% in Murambinda, Roma, Thyolo and Nsanje. The introduction of Xpert MTB/RIF in Thyolo in 2012 should reduce the diagnostic delay in many smear-negative cases and thereby help to decrease the unacceptably high mortality rate. Among retreatment TB cases, treatment success rates were highest in Imey (100%), Roma (89%) and Kibera (82%). 2.5. Drug-resistant TB Figure 15: MDR-TB treatment initiations per OCB project, 2012 In 2012, a total of 502 patients were initiated on treatment for multidrug-resistant TB (MDR-TB) across 11 different OCB projects: Failure Mumbai (32), Maputo (34, referred to NTP), Murambinda 3% Murambinda (19), Dire Dawa (7), Mon (4), Thyolo (3), Chattisgarh (2) and Nsanje (2) (fig. 15). These figures differ slightly from the overall reported ones in the OCB typology, Nsanje 0% continuous scale up of molecular drug sus- 50 ceptibility testing (DST); in 2012 Xpert MTB/ 40 RIF was introduced in five additional sites. In 30 the majority of cases, OCB provided signifi- 20 cant support in MDR-TB case management. 10 As a result of this significant scale-up of in- 0 volvement in MDR-TB, OCB will be obliged e nj sa yo Th Ki be m Ro N C am bi Im nd ey ry ak on ga tis at M 2.6. HIV/TB statistics Figure 13: Treatment outcomes in OCB projects in 2012: sputum smear-negative PTB Death to invest more in DR-TB management, preferably in collaboration with NTPs. ur hh lo registered DR-TB cases may be due to the 60 ra Ukraine. A further increase in numbers of 70 a 80 a a start of one new vertical DR-TB project in rh MDR-TB treatment initiations is mainly due to 90 C 40 The significant increase in the number of Succes rate In 2012, 14 projects out of 17 reported ac- Completed 100 cess to HTC for patients with suspected and 90 confirmed TB. Despite the reported access 80 to HTC, only 64% of all registered TB pa- 70 tients were tested for HIV in seven OCB pro- 60 jects. Among those tested, 77% were HIV 50 positive. Across all projects that reported HIV 40 positive patients, five OCB projects reported 30 use of cotrimoxazole for co-infected patients 20 with an overall rate of coverage of 77%. 10 Two OCB projects, Thyolo and Nsanje, both je N sa n lo Th yo ra a m be Ki bi m M C proportions of co-infected patients on ART were 94% and 79% respectively. Isoniazid Figure 14: Treatment outcomes in OCB projects in 2012: EPTB Death Interrupted in Malawi, submitted data on ART enrolment of registered TB/HIV co-infected patients; ur a Ro nd a ey Im ak r on C hh at ti sg a rh y 0 preventive therapy (IPT) to prevent active TB Completed 100 in HIV-infected individuals was offered to 545 90 patients in two projects reporting this activity 80 (Roma and Mumbai) – slightly more than in 70 2011 when 535 people living with HIV/AIDS 60 (PLWHA) were offered IPT in three projects 50 (Kibera, Mumbai, and Roma). 40 2.7. PMTCT 30 20 PMTCT is fully reported in the sexual and re- 10 productive health section of this report. e N sa nj lo yo Th ra a m Ki be am bi ur M Ro a nd ey Im ry ak on C hh at tis ga rh 0 C 13. HIV/AIDS and Tuberculosis Donetsk 38% Khayelitsha 35% 100 Interrupted MEDICAL ACTIVITY REPORT 2012 Chhattisgarh 0% Thyolo1% Mumbai 7% Mon 1% due to slight differences in definition. Death Mavalane 7% Donetsk (189), Khayelitsha (174), KZN (40), Figure 12: Treatment outcomes in OCB projects in 2012: sputum smear-positive PTB Interrupted KwaZulu Natal 8% PMTCT is supported in six countries (Kenya, Lesotho, Malawi, Mozambique, South Africa, and Zimbabwe) and integrated in one mater- in adolescents, feasible ways of making HIV countries that will require substantial labora- nal and child health programme in Burundi. services “adolescent friendly”, and the need tory support and supervision. In vertical HIV programmes that are reporting to develop a comprehensive counselling on PMTCT, 92% of women presenting for package covering issues of adherence, dis- antenatal care (ANC) were tested for HIV. Of closure and sexuality education. 2.11. TB infection control activities Finally, 2012 has seen the adaptation of com- Implementation of TB infection control at field munity models of care, such as the commu- level aims to ensure the implementation of nity ART groups from Mozambique and the simple and sustainable measures. Support adherence clubs from Khayelitsha, for roll-out from the infection control specialist within the 2.8. Integration of HIV, TB and DR-TB into non-vertical HIV programmes in new settings. Both programmes have Southern Africa Medical Unit (SAMU) has shown high rates of retention (97%). The been given to several HIV/TB projects Thyolo project in Malawi implemented com- (Khayelitsha, KZN, Mavalane, Dire Dawa, munity ART groups formed in collaboration Thyolo, Nsanje, Chikwawa, Donetsk and Although integration of HIV, TB, and MDR-TB with the network of people living with HIV, Mumbai) as well as to OCG projects (Shis- in non-vertical programmes remains weak in while KZN has piloted adherence clubs. Fur- elweni, Bishkek and Osh). A new TB infection OCB, some progress has been made in ther context-adapted roll-out of these com- control guidance document entitled “Assess- 2012. In the two hospital-based programmes munity-based ART delivery strategies is ing natural ventilation in resource-limited set- in Masisi and Niangara (DRC), 53 and 108 planned for 2013. tings” has been developed for project use. weeks) showed a transmission rate of 3%. patients respectively were initiated on ART in 2012. The primary health care projects in India (Chhattisgarh and Nagaland) where the HIV prevalence is very low (<0.5%) have provided HIV testing and counselling and linkages to HIV care. In addition, both projects have supported training and development of the capacity to diagnose and treat DR-TB and to ensure that the correct drug treatment is initiated. 2.10. Laboratory support in HIV/TB Xpert MTB/RIF (also known as “GeneXpert”) has been introduced at five additional sites during 2012 (Gutu, Roma, Thyolo, Nsanje and Dire Dawa, Ethiopia), making a total of 12 OCB sites that now have access to this new TB molecular diagnostic tool. Increases in microbiological detection of Mycobacteri- 3. Monitoring and Evaluation and Operational Research Four projects continue to use the electronic HIV data management tool FUCHIA. Mozambique has moved to using the electronic register exclusively while Zimbabwe is employing a tiered approach using FUCHIA, eregister, and a paper-based system for their smaller clinics. Many national programmes are beginning to introduce their own elec- HIV testing and treatment options offered by um tuberculosis and rifampicin resistance MSF or through linking to other actors should were evident in all projects upon introduction be considered in all projects, but in particular of this new assay. Pima Point-of-Care CD4 in those with a prevalence greater than 1%. analyzers were introduced in Guinea and In addition, MSF should ensure access to TB Mozambique, resulting in a total of 30 instru- Operational research (OR) is discussed fully diagnostics that can identify drug-resistant ments being implemented and more than in the operational research section of the re- strains of TB (e.g. Xpert MTB/RIF). 8,000 tests being performed. Challenges port. OR topics in HIV/TB were targeted to- faced during the introduction of these new wards the HIV/TB advocacy agenda and tools included high error rates, ensuring ad- highlighted points around TB/HIV integration, equate supervision, and quality control when the need for viral load monitoring, and the Patient and community support interventions placed in decentralized sites. use of clinical retinal screening in the diagno- in 2012 have focused on the roll-out of HIV The implementation of the HIV viral load lab- 2.9. Patient and community support viral load testing, development of specific strategies for adolescents, and adaptation of the community ART group model to different country contexts. oratory in Thyolo, Malawi, enabled a gradual roll-out of viral load testing in the district, with more than 3,000 tests performed by the end of 2012. In Zimbabwe, referral of Dried Blood With the roll-out of routine viral load testing in Spot samples prepared by nurses at the de- Kenya, Zimbabwe, and Malawi and its ongo- centralized sites and sent to a private labora- ing implementation in South Africa, an en- tory in South Africa facilitated roll out of rou- hanced adherence counselling (EAC) pack- tine viral load testing, with more than 2,000 age has been developed for those patients samples a month now being processed. All with high viral loads. Early analysis of re-sup- laboratories in the region have been enrolled pression rates following this counselling inter- in a quality control assurance program, either vention show that between 60-80% of pa- locally or in South Africa with the National In- tients are able to re-suppress their viral loads. stitute of Communicable Diseases/National A workshop on adolescents and young adults held in July 2012 highlighted the need Health Institute (NHLS) proficiency testing programme. to incorporate adapted testing strategies to 2013 will be a challenging year, with the im- identify the high burden of undiagnosed HIV plementation of viral load platforms in several tronic monitoring and evaluation systems 41 rates post-delivery (PCRs taken before 10 which may need to be integrated into MSF programmes. sis of disseminated TB. 4. HIV/TB trainings Four basic and four advanced clinical HIV/TB trainings and one DR-TB workshop were supported by the SAMU training unit. A twoweek HIV/TB programmatic course attended by 24 intersectional participants was also held for the first time in Cape Town in March 13. HIV/AIDS and Tuberculosis PMTCT intervention and the transmission 2012. In addition to these trainings, SAMU hosted a regional workshop on the management of adolescents with HIV, to share experiences both internally within MSF and with external experts. 2012 saw the launch of the development of tools to support a mentorship approach for HIV/TB support within our projects; this approach will be further developed in 2013. MEDICAL ACTIVITY REPORT 2012 those testing positive, 87% received a full 5. Looking back and ahead Lessons learned for 2012 - Despite a difficult international funding environment and OCB budget constraints along with a move towards a less toxic but more expensive first line regimen, more patients were initiated on ART compared to 2011. This reflects better treatment efficiency resulting from a mix of early initiation, decentralization, task shifting and integration with ANC and TB services. - HIV-related mortality for patients in care is in continuous decline, mostly in children where some reliable monitoring and evaluation systems (Khayelitsha, KZN, Gutu) report for the first time zero deaths at 12 months on treatment. - Altogether, vertical transmission continues to decline with increased coverage and better efficiency in our PMTCT programmes. - OCB adolescent-focused programmes have shown slow progress in 2012, despite being one of the major focuses of the Operations Department. Failure to contain a still-alarming incidence rate in the young female age groups should convince MSF to become more innovative and consider the implementation of biomedical prevention interventions as soon as scientifically validated. - As previously described, the main failure of 2012 has been the minimal commitment to integrate HIV activities within OCB’s non-vertical projects. - In 2012, OCB managed to maintain the overall level of involvement in TB control, keeping the number of patients registered for TB care in OCB projects stable. Moreover, involvement of OCB in care for DR-TB is on the rise, with numbers of patients initiated in 2012 double of those in 2011. However, the neglected area remains the tracing and follow-up of child contacts of TB cases. Integration of TB in non-vertical projects in settings with a significant TB burden remained a challenge in 2012, as little progress was achieved compared to 2011. Prospects for 2013 Challenges ahead for 2013 within the vertical projects will focus on the extremes of the HIV cascade: 42 - Extending community based testing and linkage to care activities in order to improve coverage. The relative disengagement from testing in 2012 needs to be reconsidered in that light. - Increasing the ART initiation threshold (CD4 500) in projects already having high coverage at a CD4 count threshold of 350. - Improving long-term retention in care with further community-based chronic care initiatives moving towards the concept of patient self-management, and phasing in viral load using different resource-saving strategies (point of care, Dried Blood Spots, viral load pooling). Regarding TB: - A high mortality related to smear-negative and EPTB is observed in settings with a high burden of HIV, highlighting the need to improve early TB case detection and diagnosis in HIV positive individuals. A number of OCB projects will start implementing the new “Determine TB LAM” test for early detection of HIV-associated TB in severely immunosuppressed patients. MEDICAL ACTIVITY REPORT 2012 13. HIV/AIDS and Tuberculosis - High rates of treatment interruption in DR-TB, and the low level of DR-TB/HIV integration, need to be more aggressively addressed with more attention to patient support and advocacy activities. - Integration of basic components of TB care into non-vertical OCB projects will remain a focus in 2013, and the implementation of the basic package of TB care will be reinforced. - The 2012 FDA prequalification of Bedaquiline as well as the anticipated prequalification of Delamanid may mean a new era of less toxic and more feasible DR-TB treatment. MSF MEdical Department OCB Infection Control 1. Overview Over the course of 2012, the scope of Infection Control (IC) activities continued to expand from health structures providing surgical care to other structures involved with general medical care. With OCB’s growing involvement in hospitals, in providing a higher level of surgical care (for example internal fixation for orthopaedic-trauma), and in intensive care units, along with increasingly difficult work contexts (in relation to conflict, low education levels of local staff, challenging supply processes, or climate conditions), the challenges around IC have become more complex. A case by case review followed by a tailored approach is required. More and more projects are applying basic recommendations on hygiene, such as: providing uniforms for all staff, using hydro-alcoholic solution for hand hygiene improvement, better cleaning and disinfection procedures and materials, and/or high quality sterilization and laundry services. IC is now also better represented in OCB with an Infection Control Committee as well as an infection control officer in most health structures. There is also a higher level of interest in the development of new techniques and procedures, especially regarding sterilization. lated issues were provided to numerous OCB projects (in Haiti, Pakistan, Afghanistan, India, Burundi, Ethiopia, DRC, South Sudan, Malawi, Lesotho, Somaliland and Sierra Leone). Chhattisgarh. This included assessment of the level of IC and compliance to standard precautions in the health facilities and auxiliary services (sterilization and laundry), as well as the implementation of IC measures by training and coaching of staff, defining Field visits were conducted by two IC Mobile the roles of medical, logistical and WatSan Implementation Officers (MIO). These includ- staff in IC and the establishment of an In- ed missions for: fection Control Committee. - The set up and implementation of operating theatres (OTs) and/or delivery rooms 3. Training & human resources and auxiliary services (sterilization, laundry, In 2012, a MIO with a specific OT profile was cleaning services) in Tabarre (Haiti), Khost (Afghanistan), Kibera (Kenya) and Karachi (Pakistan). The IC MIO provided support for the organization of IC activities (including training and coaching of staff, definition of the roles of medical, logistical and Water & Sanitation (WatSan) staff and the estab- -The Basic Logistics Course (BLoC) in Brussels (three times), - The Gynaecology, Anaesthesia and Surgery (GAS) week in Hong Kong, the Sexual and Reproductive Health course (once), - The WatSan operational support course (once), - The Biomed training (twice). 4. Developments and innovation -Participation in defining the IC requirements for: recruited to reinforce the set up of surgical - Internal fixation. activities. A second MIO remains involved - Sputum induction. with general IC assessment and implementation. The MIOs play a pivotal role in providing on-the-job and field-based training and technical support. 14. infection control Direct technical support and advice on IC-re- (Somaliland), and in India, Nagaland and - Finalisation of the “sterilisation and laundry” guideline. - Creation of training materials to help the implementation of standard precautions, sterilisation, and isolation set up. lishment of an Infection Control Commit- In terms of training, IC sessions were provid- tee) and advice on infrastructure. ed at the following courses: - Update of the briefing CD. -The assessment and implementation of -The Management of Health Services - Finalisation of the recommendations for bi- hygienic measures in Martissant (Haiti), (MHS) courses in Brussels (twice) and in omedical device management by medical Kaboul and Kunduz (Afghanistan), Burao Nairobi (once), staff (oxygen concentrator, suction pump). MEDICAL ACTIVITY REPORT 2012 2. Programme activities 43 The major achievements of the previous year were the openings of the internal fixation programmes in Tabarre, Haiti and Kunduz, Afghanistan. MSF invested in a European standard of hygiene with high filtration ventilation, industrial laundry services, cleaning trolleys, and an intensive care unit equipped with ventilators. These two missions, along with the experience of the Lubutu, DRC programme, demonstrate that the highest level of hygiene is challenging but possible even in low-resource settings. These successes, along with an intensive investment in field IC implementation missions and in briefing/training from headquarters, benefited IC globally by improving awareness on IC issues and solutions. -Update of the different infection control protocols: - OT dress code. - Treatment of reusable medical devices. - Personal protective equipment. - Participation in the planning and design of - Introduction of new protective material: health facilities, especially the laundry and - OT protective glasses mortuary chapter. - Surgical astronaut cap for internal fixation - Finalisation of the monitoring tools to as- - Beard mask sess adherence to standard precautions in each department. 5. Looking back and ahead Lessons learned for 2012 - The introduction of internal fixation as a surgical procedure within our trauma and orthopaedic projects required clarification from an IC perspective in conjunction with clarification of other issues around infrastructure, HR requirements, surgical protocols, and microbiological testing capacities. A guidance document on internal fixation requirements was developed. - The recruitment of an IC officer in many projects has contributed to a spectacular improvement in the quality of care through better hygiene management, particularly in the internal fixation and Lassa fever projects. - Despite greater awareness of the importance of IC in order to achieve an acceptable standard of care in OCB projects, stimulating an appropriate level of investment in various areas remains a challenge, in particular for: - The set up of support services of high quality, especially laundry and kitchen facilities. - The implementation of additional precautions to curb the transmission of highly contagious diseases, with an adequate isolation set up (including anteroom, private latrines and showers). - The planning and design of infrastructure with higher quality materials and including all essential units. - There is a need to provide guidance on laundry set up, including the selection of a washing machine/dryer and the infrastructure adaptation. A small multidisciplinary working group has been created with the electricity and WatSan referent. 44 - An OCB IC support group including all OCB referents linked to IC (epidemiology, WatSan, construction, health promotion, sterilization) has been created. It provides a platform for sharing information to achieve a multidisciplinary approach at the level of headquarters and in the field. - The standard autoclave used across our projects does not offer enough capacity to meet the sterilization needs of trauma- and orthopaedic-related surgery. Alternative autoclaves have been identified but need field-testing. They may ensure a better sterilization quality and traceability but are more complex to install and maintain. - There is an urgent need to develop and implement a standard protocol on wound and burn care in OCB. An OCB Wound Care working group has been created, but with the immense workload, an additional contractual position needs to be recruited. - The management of biomedical devices has improved with the clarification of maintenance protocols, the first biomed international trainings, and the recruitment of two biomedical MIOs (cf. Biomedical Equipment section, §2.1.). These interactions have been reinforced with improved support to the field. 14. infection control Prospects for 2013 - Close interactions with the Operations Department and Ministries of Health will be maintained and/or strengthened to promote early and committed investment and correct set-up in basic hygienic measures (standard precautions), maintaining an IC committee, or recruiting an IC officer. Special attention should be given to sterilization, laundry, hospital kitchens, cleaning services and maintenance of biomedical devices. - The IC checklists will be implemented as an indicator and monitoring tool within all OCB projects. MEDICAL ACTIVITY REPORT 2012 - An operational research portfolio will be developed in the area of IC, using the IC checklist. - A suitable opportunity to test and implement an alternative autoclave needs to be identified. - Nursing care needs to be improved by developing nursing care protocols in collaboration with the new Hospital Manager and pursuing the update of the Nursing Care guidelines. - An OCB Wound Care guideline will be created, with the introduction of new dressings materials. - Specifications and adapted requirements will be defined for laundry set up within the laundry working group, and field and cell awareness will be raised on the need to consult these guidelines when planning and designing a laundry. MSF MEdical Department OCB Intensive Care 1. Overview An Intensive Care Unit (ICU) is concerned with providing an increased level of medical care and observation to patients in a critical or unstable condition. It often requires additional technology and medical material than a standard hospital ward or care facility and is the most human resourcedependent form of care, requiring a high nurse/patient ratio in order to ensure sufficient surveillance of patients and reactivity to critical events. Depending on existing needs, some ICUs may cater to a specific medical specialty or type of patient (e.g. neonatal, paediatric, cardiac or trauma care units). Taking into account the different contexts and needs where MSF works, four levels of care have been defined for ICUs within MSF. This depends on the requirements for human resources, logistics and auxiliary services. A level 0 ICU is the most basic and level 3 is the most technical level of ICU. Our current strategy aims to achieve good standards of care in basic ICU units. In some projects, a very high level of technically advanced care is provided (e.g. mechanical ventilation). However, experiences during 2012 have highlighted the challenges these projects confront due to this high level of technology. MSF is still building its capacity towards these units and further assessment of the quality delivered and the impact on morbidity and mortality is required. 2.1. Activities at project and mission level During 2012, intensive care medical activities were provided in three OCB projects in Sierra Leone, Afghanistan, and Haiti. Specific data on intensive care was received from two pro- Table 1: ICU activities in Kunduz and Tabarre Intensive Care Units, 2012 Kunduz (Afghanistan) Tabarre (Haiti) Total admissions 314 192 Proportion children under five 3.9% 2.9% Mortality rate 7.2% 7.5% Referral rate 10.3% 3.9% Bed occupancy rate 76.1% (4 beds) 33.1% (7 beds) Average length of stay 3.7 days 4.3 days 45 2. Programme activities Tabarre. This ICU has a capacity of seven In collaboration with the paediatric team, beds. While invasive mechanical ventilation standards are being developed to ensure the has yet not been implemented, non-invasive provision of quality care and treatment for se- 2.2.1 Afghanistan ventilation is available. The priority in this set- verely ill children (making up a significant pro- ting has been to ensure the basic knowledge portion of the project’s beneficiaries), such as OCB provides intensive care in Kunduz pro- of national staff before upgrading the unit. the implementation of early warning score ject, a trauma centre in the north of Afghani- The achievements in terms of quality and systems and the development of manage- stan, which had four beds in 2012. The Kun- standards of care have been very high, ment tools for conditions such as shock and duz ICU is the most complex unit run by thanks to the hard work of all national and severe malaria. OCB because it provides invasive ventilation, international staff. 2.2 Country specific activities a major challenge for all staff and support personnel involved. Since the project’s start, the international staff’s main aim has been to train national staff and ensure the provision of quality care. The achievements so far are impressive, but the unit still needs regular supervision of daily activities. 2.2.2 Haiti 2.2.3 Sierra Leone 3. Human resources and training International doctors and nurses special- The Gondama Referral Centre (GRC) in Bo ized in intensive care medicine have been district provides paediatric and obstetric recruited as a response to the needs in the health care. The capacity of the ICU is 30 field. The main challenge around human re- beds. This centre delivers a more basic de- source capacity for intensive care relates to gree of care than the prior two centres, cor- the skills of national staff. Doctors and responding to an ICU level 1. The patholo- nurses in charge of ICU patients should Since February 2012, OCB has been running gies seen here differ from the other units, as have specific knowledge, attitude, and a hospital for acute trauma and surgical pa- infectious diseases are the main cause of skills related to the physiology of the criti- thologies in a container-based structure in critical illness. cally-ill patient, the specific clinical man- MEDICAL ACTIVITY REPORT 2012 (table 1). 15. intensive care jects, which had a total of 506 admissions agement strategies, and the life-saving critical patients by helping them to recognize procedures required. these severe cases early, thus reducing the The development of the Basic Assessment and Support of Seriously Ill Patients in Developing Healthcare Systems (BASIC DHS, cf. Emergency Medicine section, §3.) training was a response to this need as it tackles the issue of non-specialized doctors in charge of time between recognition of the critical illness and the required interventions such as oxygen therapy and basic airway management, volume therapy and transfusion, surgery, antibiotic therapy, and/or management of lifethreatening disorders. 4. Looking back and ahead Lessons learned for 2012 - To better understand and improve intensive care activities, improved monitoring and evaluation of these activities needs to take place through the implementation of effective surveillance systems. - A need for more specific documentation was identified: guidelines and standardization for the management of intensive care patients, and protocols for the treatment of specific critical illnesses are required. - A balance needs to be found between the expectations for intensive care activities and the required preconditions and field realities. Prospects for 2013 - Implementation of the data collection tool in ICUs will be monitored. - The strategy for intensive care standards will be presented, and collaborations with other medical units will be developed 46 in order to disseminate tools to reach these standards. - Expatriate staff will continue to be followed up by the intensive care referent. MEDICAL ACTIVITY REPORT 2012 15. intensive care - The BASIC DHS training will be continued for national staff working in ICUs. MSF MEdical Department OCB LABORATORY 1. Overview 2012 saw the introduction of new laboratory activities, along with the expansion of existing tools and activities. For example, the use of an automated tuberculosis (TB) diagnostic test, the Xpert MTB/RIF, was expanded to additional projects, Dried Blood Spot (DBS) viral load testing in Malawi and Zimbabwe was gradually rolled out, and the UNITAID Memorandum of Understanding (for funding of HIV diagnostics) was signed at the end of the year. 2. Programme activities The quality of OCB laboratories was recog- - Preliminary results of the viral load pooling nized this year, when the viral load laboratory study in Malawi showed satisfactory re- 2.1. Laboratory activities at a country and project level in Thyolo, Malawi obtained a certificate of sults with significant cost savings; final re- excellence in quality control from the Centres sults will be published in 2013. One oral for Disease Control (CDC), and the Buhera, presentation on the roll-out of the Xpert Zimbabwe laboratory obtained two stars in MTB/RIF diagnostic tool in MSF and three the World Health Organisation (WHO) ac- posters on CD4 and viral load were pre- creditation process. sented at the African Society of Laboratory bwe, South Africa, Malawi, Lesotho, and Afghanistan. Four laboratories were closed (in DRC, Ethiopia, Malawi, and Mozambique) (table 1, Annex). 2.2 Use of a reference laboratory Medicine in Cape Town. 4. Operational Research and developments - Excellent results were obtained in a study in Buhera, Zimbabwe, evaluating the usefulness of CD4 stabilization tubes for CD4 OCB continued to work with the Institute of testing; consequently, these tubes have Tropical Medicine in Antwerp, Belgium, which replaced the standard EDTA tubes. This served as an HIV reference laboratory. Addi- substitution allows longer CD4 storage tionally, OCB continued collaborations with time at room temperature, a key feature for the National Institute of Communicable Dis- decentralized laboratory sites. eases/National Health Institute (NICD/NHLS) and Global Laboratories in South Africa. - In Malawi, final results of a study on finger prick DBS viral load validation with the Nu- 3. Quality control cliSENS platform proved promising and OCB laboratories continued to be enrolled in district is planned in 2013. In contrast, a the Proficiency Testing Programme of the roll-out of the diagnostic technique in the Zimbabwean study on finger DBS valida- - The number of sites implementing Xpert MTB/RIF in OCB increased from seven laboratories in 2011 to 12 in 2012, representing an increase of 71%. Similarly, an expansion in the number of PIMA POC 47 activities were introduced in Ethiopia, Zimba- CD4 was seen in 2012 with a total of 30 instruments deployed in five countries (Guinea, DRC, Mozambique, South Africa and Lesotho). - An operational research study was initiated in Afghanistan on antibiotic resistance in the population attending the Lashkar-Gah hospital in Helmand. This study represents a major initiative to understand the scope of the problem of antibiotic resistance in MSF contexts, and results are expected in 2013. NICD/NHLS. With the implementation of the tion with the Roche Taqman platform yield- PIMA Point-Of-Care (POC) CD4 machine, ed very disappointing results, mainly a there was an increase in the number of sites, poor specificity which led to a higher rate mainly clinics, using this device. OCB contin- of false positives. A way to overcome this During 2012, two expatriate and three na- ued to participate in proficiency testing to problem is to raise the cut-off used to de- tional staff attended the laboratory training ensure that laboratories monitored their qual- termine virological failure, or finding ways organized by MSF Austria. ity regularly and staff remained motivated. to remove proviral DNA when using whole 5. Training 16. Laboratory 33 missions in 20 countries. New laboratory blood. MEDICAL ACTIVITY REPORT 2012 Laboratory activities were supported in over 6. Looking back and ahead Lessons learned for 2012 - The introduction of new diagnostic tools in OCB represents new challenges in terms of quality control and monitoring. Although the rate of inconclusive results with Xpert MTB/RIF decreased considerably in 2012, it still remains relatively high. A similar trend of invalid results is observed with the PIMA POC CD4; monitoring a high number of sites implementing new technologies is time-consuming (cf. Biomedical Equipment section, §2.1.) and more automated solutions such as mobile network connectivity options are urgently required. - A wide range of emerging operational research topics represent both promising areas for innovation in OCB laboratory activities and an added work load in terms of laboratory support. Prospects for 2013 2013 will be the year: - Of viral load implementation in OCB projects. Five countries (Malawi, Zimbabwe, Mozambique, Lesotho and South Africa) will be introducing and scaling up lab-based viral load testing as well as POC viral load as part of a UNITAID-funded initiative. - Of the use of molecular biology to identify Plasmodium falciparum resistance in Cambodia, in collaboration with the Pasteur Institute in Phnom Penh (cf. Malaria section, §2.3.). MEDICAL ACTIVITY REPORT 2012 16. Laboratory 48 - Of microbiology implementation in one of the OCB Trauma Centres in Afghanistan. MSF MEdical Department OCB Malaria 1. Overview After some years of decrease, the total number of confirmed malaria cases treated by OCB in 2012 remained stable. However, malaria continued to be a leading cause of morbidity and mortality in OCB projects, and some missions, such as South Sudan and Niger, observed a substantial increase in cases from 2011. We continued the roll-out of the new treatment for severe malaria, injectable artesunate. Monitoring of results thus far has shown that this treatment is effective and safe, and that its implementation is feasible. A new malaria project was opened in Kirundo, Burundi, with an initial focus on the correct management of severe malaria. The malaria project on artemisin resistance/tolerance in Cambodia has been approved and preparations are ongoing for a start in 2013. OCB, together with other MSF sections, intervened for a malaria emergency in DRC. This intervention highlighted again the challenges for timely detection and adequate response, including prevention. 2. Programme activities Figure 1: Total and confirmed malaria cases in OCB projects, 2004-2012 700000 2.1. Malarial cases pared to 2011. Approximately 6% (17,752 cases) were se- 49 was 277,086 (fig. 1), a slight increase com- 500000 400000 300000 200000 vere cases of malaria. DRC, Sierra Leone, 100000 and Niger represented the missions with the 0 highest burden of severe malaria. More than 2004 2005 2006 2007 9 out of 10 malaria cases were treated in just four missions (fig. 2), and one of those, DRC, represents 40% of the cases. 250000 tection with the implementation of malaria care and intervention. For South Sudan, OCB launched a new refugee project (cf. 3% 2010 2011 2012 2011 2010 2012 200000 150000 100000 50000 Figure 2: Confirmed malaria cases 9% Confirmed malaria cases in DRC, this was mainly due to increased de- 2009 Figure 3: Malaria trends in OCB-missions, 2010-2012 A considerable increase was seen in missions such as DRC and South Sudan (fig. 3): 2008 Year 0 4% 40% DRC Niger Sierra Leone South Sudan 17. MALARIA firmed malaria cases treated in OCB projects 600000 Number of malaria cases During the year, the total number of con- Total cases Confirmed cases Niger 18% 26% South Sudan Emergency Unit section, §2.2.1.), which ex- Sierra Leone plains in part the increase; however, an im- Mauritania pressive increase in malaria cases (141%) is Other missions also observed for existing projects. In the Guidan Roumdji project (Niger), the number of cases increased by 72% compared to 2011. 2.2. Diagnostics In 2012, 476,056 Rapid Diagnostic Tests (RDT) were performed during OPD consultations. A high proportion of positive RDT – indicating a high malaria endemicity – was seen in projects such as Pibor, South Sudan (60%); Mauritania (78%); Guidan Roumdji, MEDICAL ACTIVITY REPORT 2012 DRC Niger (59%); Bo, Sierra Leone (59%); and all Figure 4: Evolution of the proportion of confirmed malaria cases, 2007-2012 projects in DRC. increasing over the years, up to 98% in 2012, indicating that the MSF-policy of systematic parasitological confirmation of all malaria cases is well implemented (fig. 4). 2.3. Case management – artemisinin-combination therapy Resistance/tolerance to artemisinin has now 100,0 Proportion confirmed malaria cases The proportion of confirmed malaria has been 98,0 96,0 94,0 92,0 90,0 88,0 86,0 84,0 2004 2005 2006 2007 2008 2009 2010 2011 2012 been documented in four countries in the Mekong-region, including Cambodia. A new Rectal Artesunate remains one of the most project focusing on artemisinin resistance/ effective and safe pre-referral treatments for tolerance in Preah Vihear province, Cambo- use at peripheral healthcare levels and more dia was approved. The objective is to con- OCB missions began using this drug in 2012. tribute to the elimination of resistant/tolerant Plasmodium falciparum malaria. Preparations are ongoing to implement a targeted screening and treatment strategy, using PCR as a diagnostic tool and Dihydro-artemisinin/ Piperaquine as treatment. The network of Village Malaria Workers will be reinforced, and a collaboration with the private sector will be considered. The project will be launched in 50 2013. 2.4. Case management – severe malaria After publication of the AQUAMAT-study (showing the superiority of Artesunate IV/IM over Quinine IV in the management of severe malaria in African children), the MSF policy is to recommend Artesunate IV/IM as the treatment of choice for severe malaria. Implementation started at the end of 2011, and throughout 2012 OCB projects gradually replaced artemether with injectable artesunate. By the end of 2012, all projects with a high malaria burden were using artesunate, except South Sudan and the emergency interventions in Mali and Mauritania. Around 1,400 patients in 19 MSF-projects 17. MALARIA (all sections) have been monitored specifically and the results so far are very promising: the average treatment duration is short (75% of the patients can switch to oral treatment after 24 hours), clinical outcomes are good (93% cure rate) and very few problems MEDICAL ACTIVITY REPORT 2012 have been reported concerning the preparation of the drug. These results demonstrate the feasibility of implementing artesunate. Furthermore, a package of documents for its practical use, the quantification of needs and a FAQ-sheet have been developed. 3. Re-positioning of OCB malaria activities With the opening of a vertical malaria project in Cambodia focused on the elimination of At the end of 2012, OCB finally launched a resistant/tolerant Pf-malaria, OCB is en- malaria project in Kirundo province, Burundi, gaged for the first time in malaria-elimination that will focus during a first phase on the cor- activities in general and resistant/tolerant rect management of severe malaria at all lev- malaria in particular. Additionally, in Burundi, els, from the community to the hospital. which has been defined as a project by 2.5. Community management of malaria After the closure of the project in Sierra Leo- choice with a focus on malaria, OCB has the opportunity to implement innovative malaria control activities. ne, OCB no longer has community projects 4. Operational Research for malaria. However, the new malaria project A study to evaluate patient adherence to in Cambodia will have a considerable com- fixed-dose combination Artesunate/Amodi- munity component, using a network of Vil- aquine was performed in Sierra Leone, with lage Malaria Workers and Mobile Migrant results still pending. Workers for the detection of cases and for mass screening. With MSF being one of the first implementers of injectable artesunate in Africa, it was 2.6. Outbreaks agreed among all MSF sections to document Confronted with an emergency malaria situa- oped to monitor the profile of patients receiv- tion in different regions in DRC, OCB organized a number of short-term interventions in the Maniema, Equateur and Oriental provinces. The focus of the intervention was on case management: more than 70,000 cases of simple malaria and 2,100 cases of severe malaria were treated in mobile clinics, health centres and hospitals, and a considerable number of transfusions were done. Together with other MSF sections, an intersectional advocacy report is being prepared. 2.7. Prevention Vector control (through distribution of longlasting insecticide-treated nets (LN) and Indoor Residual Spraying (IRS)) is an essential and effective component of any malaria control programme. However, the MSF Malaria policy is not always implemented correctly in our existing projects or during emergencies. this experience. A specific tool was develing the treatment, the duration of treatment, the route of administration, treatment outcomes and problems related to treatment preparation or administration. So far, about 1,400 patients have been monitored. In Burundi, a baseline survey was done, evaluating mortality, malaria health seeking behaviour and coverage of preventive tools such as LN. 5. Looking back and ahead Lessons learned for 2012 - Adherence to ACT (Fixed Dose Combination) and monitoring of this adherence needs to be strengthened. - The emergency intervention in DRC has highlighted some issues: malaria surveillance, timely detection and adequate response to malaria outbreaks remain a challenge in most of the outbreak-prone areas where we were working in 2012. - Prevention of malaria (through provision of LN) was not always sufficiently or correctly implemented, during emergencies as well as in some routine activities. - In line with the decreasing malaria burden, the proportion of non-malaria fevers has increased. There is, therefore, a need to improve the diagnostic tools (such as RDT) and protocols for differential diagnosis of malaria and to improve the management of fever in children. Prospects for 2013 - A pan pLDH-test will hopefully be validated in 2013. - In the malaria project in Cambodia, PCR and a test for detecting G6PD-deficiency will be evaluated. - We will evaluate the performance of RDT, microscopy and PCR for the diagnosis of malaria in neonates. - Further roll out of artesunate IV/IM will continue in 2013. Specific monitoring of the use of artesunate in pregnant women, malnourished children and at peripheral levels is planned. - The use of rectal artesunate as a pre-referral treatment should be reinforced. - An evaluation of the community component of the malaria project in Sierra Leone is planned. Community management of malaria – using Village Malaria Workers and Mobile Migrant Workers - will be a key-component of the project in Cambodia. - An adapted strategy for the prevention of malaria in pregnancy needs to be developed, taking into account factors such as - The intersectional guideline for malaria outbreaks will be finalized. Surveillance, timely detection and adequate response in case 51 epidemiological context and/or efficacy of sulfadoxine-pyrimethamine. of outbreaks need to be reinforced. Vector control, through the distribution of LN, should be a key component of each intervention. Based on the experience in DRC, the best strategy for these high-endemic malaria contexts needs to be evaluated. - Resistance to artemisinin, emerging in the Greater Mekong Region, has not been documented yet in Africa. In regard to this, the efficacy of current first line ACT should be monitored. - A new preventive strategy, the Seasonal Malaria Chemoprophylaxis, is planned in Niger, and might be considered for South Sudan. - The prevention of malaria through distribution of LN (to pregnant women at antenatal care (ANC) or during emergencies) needs to be MEDICAL ACTIVITY REPORT 2012 17. MALARIA strengthened. MSF MEdical Department OCB Medical Structures – Inpatient Department 1. Overview Secondary health care and/or hospital capacity allows for the provision of medical care for complicated cases that are referred from peripheral structures. This has an important impact on acute mortality. Since 2005, OCB has been more and more involved in secondary healthcare, a shift in strategy that places the organization in new terrain. In 2012, €75 million were dedicated to running Inpatient Department (IPD) structures in 16 different countries, including in emergency contexts, numbering a total of 2,088 beds and catered for by approximately 5,794 staff. In these structures, a variety of activities coexist, requiring a specific management approach. Hospital management is “the ability to organize human resources, technology, supplies and finances to ensure provision of quality patient care within a structure” (World Health Organisation (WHO)). For OCB, there is a need to standardise the multi-disciplinary support approach to running these health facilities. Different criteria are used to classify secondary health care structures, depending on their specific characteristics. In OCB four types of secondary health care structures are recognized: - General Hospital - seven: Lashkar-Gah and Ahmad Shah Baba (Afghanistan); Lubutu, Masisi and Niangara (DRC); Nagaland (India); and Burao (Somaliland) 52 - Service or Disease Specific Activities - twelve: Khost and Kunduz (Afghanistan); Gitega, Kabezi and Kirundu (Burundi); AIDS Kinshasa (DRC); Tabarre (Haiti); Dakoro and Guidan Roumdji (Niger); Timergara (Pakistan); Gondama Referral Centre in Bo (Sierra Leone); and Khayelitsha (South Africa) - Hospital Based Activities - seven: Imey (Ethiopia); Martissant (Haiti); Dargai (Pakistan); Galgaduud (Somalia); Gogrial and Pibor (South Sudan); and Shaeria (Sudan) - Emergencies - four: Mali; Mauritania; South Sudan (Maban region) ;and Syria 18. medical structures – inpatient department About half of these health facilities are managed exclusively by OCB. Nearly half (47%) of the 30 facilities are located in “default” settings (location chosen by the exigency of an acute crisis). 2. Programme activities 2.1. Activities at project and mission level In 2012 OCB provided inpatient care in 30 health facilities, including during emergency interventions (fig. 1). - One in-depth feasibility study was performed for the opening of a paediatric hospital in Juba, South Sudan. Following this analysis, OCB decided not to start this project. MEDICAL ACTIVITY REPORT 2012 - Three structures were opened: Khost (Afghanistan), Kirundu (Burundi) and Tabarre (Haiti). - Five structures were closed/handed over during 2012: Lashkar-Gah (Helmand, Afghanistan), Lubutu (DRC), Dakoro (Niger), Dargai (Pakistan) and Galgaduud, Somalia. - After the 2012 Annual Review of Operations, the decision was taken to close/ Figure 1: OCB medical structures offering IPD services, 2012 hand-over five more structures in Emergency 13% 2013/2014: Kabezi (Burundi), Niangara (DRC), Imey (Ethiopia), Nagaland (India) and Khayelitsha, South Africa. - The emergency pool intervened in four Continued 43% To be closed 17% countries where IPD structures and/or surgery was implemented to answer health needs: Mali, Mauritania, South Sudan and Syria (cf. Emergency Unit section). - Thus, excluding the emergency projects, 16 health facilities with IPD bed capacity (3 of which new projects) will remain at the end of 2013. Closed 17% New 10% 2.3.1 Paediatrics The GRC (Bo) and Masisi are in the top five for number of beds and staff and total number of – Dakoro and Kirundu were excluded from this analysis due to missing data (fig. 2). Staff size at each site ranged from 300 to 600 (fig. 3, no data for Galgaduud, Somalia). The Lashkar-Gah hospital in Helmand, Afghanistan saw the largest number of consulta- At the end of 2012, the GRC in Sierra Leone admissions among all OCB IPD structures. and the hospital in Guidan Roumdji were the The two trauma centres managed by MSF two remaining structures with high volumes (Tabarre, Haiti and Kunduz, Afghanistan) do of paediatric (under 5 years of age) patients not have more than 120 beds or the highest – 7,601 and 10,166 respectively. Two pro- number of yearly admissions, but they do jects admitting an important number of chil- have a high number of staff because of their dren were closed this year, Lashkar-Gah and high level of specialisation. Dakoro. There was a substantial improve- tions, at 18,231 (including deliveries) in 2012 Ahmad Shah Baba (district hospital in Kabul, ment in the data collection for neonatal care (fig. 4, no data for Lubutu, DRC). Lashkar- Afghanistan) has a high number of admissions this year; data was collected in nine OCB Gah, which was one of the largest hospitals for deliveries (9,245 or an average of 770 per structures (cf. Paediatric Care section, §2.2.). in terms of numbers of beds, staff and ad- month), which in 2012 represented 84% of In addition, this year saw an important invest- missions, was handed over to OCA in 2012. the total admissions to this hospital. Guidan ment in terms of providing care to this subset Roumdji in Niger, a project focusing on paedi- of the paediatric population (fig. 5). Figure 2: Top five OCB medical structures offering IPD services – number of beds, 2012 Lubutu; 144 GRC (Bo); 220 atric care and malnutrition, follows Lashkar- Knowing the proportion of under-five patients Gah as the IPD structure that has absorbed which is malnourished remains a challenge. the highest number of overall admissions in The existing data collection system does not 2012 and half of all paediatric admissions in permit an analysis of the proportion of chil- OCB. It averaged slightly less than 1300 ad- dren coming in with acute illness who are missions per month, of which 66% were in the also undernourished. This data is vital be- paediatric ward, which has about 60 beds. cause the case management (in terms of drug and fluids) is different from that for a 2.3. Paediatrics, deliveries and surgery normally nourished child, and nutritional treatment is crucial for their convalescence. According to the data collected for the 2012 Burco; 149 Helmand; 170 2.3.2 Under-five mortality (including neonates) typology exercise (cf. Health Informatics section, §2.4.) there were: Masisi; 150 N Figure 3: Top five OCB medical structures offering IPD services – size of staff, 2012 Masisi; 310 Helmand; 592 The highest percentage of mortality in under- % fives occurred in the projects of Kabezi (Bu- Total IPD admissions 135,280 Admissions (without deliveries and ITFC) 73,210 54.1% Paediatric < 5 admissions 35,435 26.0% Neonate admissions 2,779 2.1% Maternity admissions 52,595 38.9% Paediatric < 5 mortality 2,174 6.2% Neonatal mortality 419 15.1% rundi) and Lashkar-Gah (Afghanistan). Neonates represent all under-five mortality in Kabezi and Khost, as no other paediatric cases were admitted to these IPDs (fig. 6). Cf. Paediatrics section for an in-depth analysis of these trends. 2.3.3. Deliveries Although the Khost project opened quite re- IPD: inpatient department; ITFC: inpatient therapeutic feeding centre Tabarre; 312 cently, it already saw a high number of deliv- GRC (Bo); 381 Figure 5: Paediatric admissions to OCB medical structures offering IPD services, 2012 Kunduz; 356 Figure 4: Top five OCB medical structures offering IPD services – number of admissions, 2012 20000 18000 Paediatric (<5), excl. neonates 16000 Masisi; 9976 Neonates ITFC admissions IPD >5 14000 Helmand; 18231 53 On average, hospitals had a size of 167 beds 18. medical structures – inpatient department 2.2. Hospital Size (excluding emergencies) 12000 10000 Ahmad Shah Baba; 10898 6000 4000 2000 i ez l ria og G Ka b t sa n ar tis M ab an M co Bu r Ba b a ra ga Sh ah ad M as isi Da ko ro an d H el m RC G N ia n Ah m Guidan Roumdji; 15050 G GRC (Bo); 12024 ui da n Ro u m dj i (B o) 0 MEDICAL ACTIVITY REPORT 2012 8000 3. Developments and innovation Figure 6: Mortality for children under-five admitted to OCB IDPs, by project, 2012 16.0% To reinforce hospital management in the field, Threshold Mortality rate OCB has chosen to invest in human resourc- 14.0% es at headquarters, thereby permitting a 12.0% transversal and multidisciplinary approach. 10.0% The positions opened include: - A hospital management coordinator 8.0% based in the Operations Department (January 2012) 6.0% - A hospital logistician based in the logistics 4.0% back office (November 2012) 2.0% - Transition from part-time to full-time technical hospital management referent in 0.0% Khost Tabarre AIDS Kinshasa Dargai Kunduz Shaeria Nagaland Imey Pibor Kabezi Gogrial Martissant Maban Burco Ahmad Shah Baba Dakoro Niangara Masisi Helmand GRC (Bo) Guidan Roumdji the medical department (recruitment ongoing) To monitor priorities and guide the way forward, the Operations middle managers, together with the hospital management coordinator formed a steering group that is accountable to the Board of Directors. eries (more than 1,000 per month). In Ahmad Shah Baba (Afghanistan), Masisi (DRC), and Burao (Somaliland), the number of monthly deliveries is also quite high (more than 300/ month). The projects of Kabezi and GRC exclusively treat obstetric cases with complica- 54 tions and do not manage normal deliveries. 2.3.4. Surgery Kunduz and Tabarre are the two trauma centres run by OCB; they are important in terms of surgical activities, level of care (internal fixation), and hygiene standards. Gitega focuses exclusively on fistula care. All other projects have an operating department where MSF focuses on necessary, life saving surgery, including c-sections. These activities are discussed in more detail in the Surgical 18. medical structures – inpatient department Activities section. 4.Training and human resources Because the past year was spent in large part on the set-up of this new hospital management approach, there was little investment in human resources for trainings. The first Hospital Management Team Training is planned for November 2013; it will focus on the hospital management team in MSF contexts. 5. Looking back and ahead Lessons learned for 2012 - In 2012, one of the objectives was to get a global overview and inventory of the situation within OCB (staff ratios, cost, workload, etc.). This was more challenging than anticipated, because the existing reporting system and data collection has been developed in terms of a project approach. It proved challenging to find and centralize information and data specific to hospitals (number of beds, staff, budget, medical data, etc.). - A pilot hospital platform was set-up for the upgrade of the GRC in Sierra Leone and is still ongoing. The objective is to provide MEDICAL ACTIVITY REPORT 2012 a transversal technical approach (a representative per department) to support operations. The GRC committee was held on a bi-weekly basis throughout the year. It has been (and still is) challenging to find appropriate solutions for a running 220-bed facility, taking into account the urgency (challenges related to Lassa fever endemicity). - Contacts and regular platforms (every three months) were created with OCP and OCBA; sharing of information, tools and data is ongoing. - In order to consolidate knowledge, ensure quality health care, and maintain capacity, the number of hospitals in OCB is not increasing (following the motion of the board). Within the remaining hospitals, focus will be placed on building internal capacity, expertise and standards through capitalisation, training, and rotating a pool of experienced human resources. Prospects for 2013 - 2013 started with a hospital steering committee (Operations middle managers), which should re-enforce OCB accountability, monitoring, guidance and support for hospital activities, as well as ensure stronger hospital management in the field and at the level of headquarters with recommendations, tools and trainings. - In collaboration with the training unit, a comprehensive competency-based curriculum for training a Hospital Management Team in MSF contexts is being developed. This training should start at the end of 2013. Parallel with this, a toolkit and guidelines are being MEDICAL ACTIVITY REPORT 2012 18. medical structures – inpatient department 55 developed with the goal of clarifying concepts and approaches for improving managerial competencies. MSF MEdical Department OCB Mental Health 1. Overview Compared to the previous year, in 2012 Mental Health (MH) activities were much less integrated into the medical activities during emergency interventions. While MH is usually particularly implicated in violence/ conflicts, displacement of populations, and natural disasters, activities this year were more limited, as security issues did not permit the missions of expatriates to implement MH activities onsite (e.g. in Mauritania, Mali or Syria). MH interventions in emergencies were integrated mainly into the medical activities in three camps in South Sudan; these activities focused predominantly on nutrition. 56 As seven projects/MH components were closed, the portfolio of MH interventions was reduced for ongoing projects. New MH projects developed in large part as additional components to projects in countries with pre-existing activities. For example, in Pakistan, MH expanded into a second project, integrated in the outpatient department (OPD) in an urban slum of Karachi; in Afghanistan, MH was integrated into the OPD in Lashkar-Gah, Helmand (and handed over to OCA) and an assessment conducted in Kunduz has led to planned MH activities for the victims of trauma in 2013; and in Egypt, a sexual violence component was added to the vertical MH programme in Egypt, focusing on migrants. Some activities which were planned for 2012 were ultimately cancelled due to changed circumstances. These included MH for victims of violence in Bahrain and a rehabilitation centre for victims of torture in Libya. Because MSF cannot maintain a constant presence in an increasing number of contexts, in some cases professionals were identified and trained outside of their country of origin (e.g. Bahrain and Syria) to serve MH needs. This type of intervention is efficacious on condition that it is accompanied by follow-up through remote control clinical supervision and technical support. 19. mental health The integration of psychiatric care in MH activities continued in 2012, both directly by MSF (Egypt, India, South Sudan, and Kenya) and through a referral system (Afghanistan, Pakistan Ukraine, and Libya). Databases and patient files were accordingly implemented in several projects. To increase technical support, a part time consultant psychiatrist was recruited mid-year. New fields of intervention were discussed at the operational level over the course of 2012: hepatitis C treatment (MH would be involved due to the possible psychiatric effects of the drugs) and rehabilitation for victims of torture (where analysis of the feasibility of a possible project has started). In early 2012, the position of “HIV/TB community and patient support advisor” was created to reinforce the support to HIV-TB projects (South Africa, Guinea, Malawi, DRC, Zimbabwe, Kenya, Mozambique, Ethiopia, and North Sudan), with regular collaboration with the MH and Health Promotion advisors. The position is linked to the Southern Africa Medical Unit (SAMU), but based in Brussels to allow exchange with the other technical advisors. It is anticipated that this position will permit a holistic approach to care that includes emotional, educational and social aspects and will facilitate the development of strategies at the community level. 2. Programme activities During 2012, OCB provided non-emergency MH activities in 25 projects across 15 coun- MEDICAL ACTIVITY REPORT 2012 tries. At the beginning of 2012, 18 projects in 13 missions included an integrated MH component, in addition to the HIV/TB programmes (table 1, Annex). Additionally, MH activities were included in five emergency interventions (table 2, Annex). Despite a general reduction of MH activities by the end of the year, the diversification of contexts has permitted the continuation of a wide variety of activities, including individual 2.1 South Sudan (Doro Camp) consultations, awareness activities, psycho- Since the end of 2011, 46,000 refugees have education, Psychological First Aid (PFA), fled to the refugee camp of Doro, Maban training of medical staff and other identified County, to escape ongoing violence in the professionals as teachers, and community Blue Nile state of North Sudan (cf. Emergen- mobilisation as support in the implementa- cy Unit section, §2.2.1.). A vast majority have tion of group activities to restore collective endured traumatic experiences during their coping mechanisms. Below, two specific displacement (lost family members, bomb- noteworthy contexts with an MH focus are ing, destruction of villages, and general ex- discussed. perience of violence) on their way to the camp. At Doro, many were still living under stressful conditions, facing food shortages, team of seven community workers from dif- rial, meeting of experts/centres for reha- lack of basic non-food items, and in some ferent communities raised awareness about bilitation of torture, participation in the con- cases, lacking water or sanitation. MH activi- MH and SV among migrant groups. During cept note, organization of training for the ties began in mid-August. A team of five psy- 2012, the number of patients increased reg- field team). chosocial workers and seven home visitors ularly, with a total of 348 patients this year. was recruited, trained and continually super- Half were followed by both a psychologist vised by a clinical psychologist expatriate. and a psychiatrist. The majority came from 4. Training and human resources MH activities were focused along three axes Eritrea, Sudan (North and South), Ethiopia During 2012 a number of different MSF train- of intervention: and Somalia. The most common diagnoses ings included an MH component: the physical health but also the mental status of caregivers can be affected, making it difficult for them to find resources to stimulate their child. This lack of psycho-stimulation can have adverse consequences for the child’s development and MH, especially when combined with malnutrition. In Doro, the team started daily group sessions on mother and child psycho-stimulation, group order and chronic anxiety disorders. Most migrants had experienced violence in their port to survivors of SV. -The Management of Health Services Egypt: 62% of MH patients reported direct (MHS) training: MH policy and integration physical violence (among them 34% report- and role of the medical staff. ed spontaneously, at the initial session, tor- - The Populations in Precarious Situations ture/ill treatment). The medical component (PSP) course – co-facilitation of the emer- will therefore be reinforced next year. gency module, and evening sessions on 3. Technical guidance Over the course of 2012, a number of activi- counselling sessions. ties were undertaken in relation to the devel- teams were trained for identification of MH midwifes: a module on psychological sup- country of origin, during their journey, or in discussions with mothers, and individual - In the main clinic and health posts: medical - The SRH training course for nurses and opment/revision of MH tools and guidelines, including: disorders and an MH team provided indi- - Finalisation of the “manual of training in vidual counselling sessions, group ses- MH for primary health care professionals” sions for PFA and psycho-education, and and the start of its translation into French group discussions. Psychiatric care was (intersectional). MH. The following external trainings were also provided: - Institute of Tropical Medicine – Master of Public Health: mental health within humanitarian interventions. - Training for surgeons with the University of Verona: stress management. - University clinic Saint Luc: mental health interventions within MSF (HUMA course). added in the main clinic at the end of 2012. -Start of the guideline for specific ap- - In the community: MH awareness and PFA proaches and techniques to working with OCB continued to collaborate with OCA in children and teenagers (intersectional). the organisation and running of a two week were promoted, severe cases were identified, and home visits were performed when necessary. Special attention was devoted to awareness and care of Sexual and Gender-Based Violence (SGBV). 2.2 Cairo This project aimed to provide comprehensive medical and MH care to documented and undocumented migrants in Cairo. Cairo is estimated to have between one and four mil- - Development of protocols and tools related to psychiatric care. -Development of practical and standardized tools for screening MH disorders and for evaluating the outcome of psychiatric support. - Review of the chapter on postpartum MH disorders in the Sexual and Reproductive Health (SRH) guideline. MH training course in the Netherlands for field psychologists and counsellors (national and international staff). Seven OCB candidates participated and there was an increasing involvement from other sections for the training modules. The possibility of running the same decentralised course in French is being considered between the sections. In terms of human resources, 25 psychologists/psychiatrists were deployed to the field, lion undocumented migrants, who suffer - Participation in the review of a SV pocket among whom seven were on their first mis- from barriers to care, stigmatisation, and guideline (chapter about psychological sion. This represents a decrease of expatri- harsh living conditions. The MH clinic opened support and psychotropics). ate positions, due mainly to nationalisation of in February 2012, with a specific sexual violence (SV) component added in April. A team of national clinical psychologists, psychiatrists and nurses was recruited to provide comprehensive MH care at the clinic. A private psychiatric hospital was identified in case of the need for hospitalization. A social worker was also added to link the patient with existing social services, provide support to the administrative procedures, and rein- - “MH key messages” for the Health Promotion manual. 57 malnutrition. During a food crisis, not only chronic psychosis, post-traumatic stress dis- some positions and closure of certain projects. 19. mental health care practices and MH have an impact on -Standardization of MH job profiles and competencies for MH professionals. - Compilation of MH documents translated into Arabic. - Participation in developing the patient support guideline for MDR-TB (will be finalized in 2013). force the mutual referrals with the other ac- - Development of MSF expertise about care tors working with migrants. In addition, a for victims of torture (compilation of mate- MEDICAL ACTIVITY REPORT 2012 - In the therapeutic feeding programme: child were depression (moderate and severe), 5. Looking back and ahead Lessons learned for 2012 Psychiatric care is still too often excluded from humanitarian care, even though such a gap in treatment not only has an impact on the dimension of health, but can also have a negative affect on social integration and access to health care. OCB has already made considerable efforts to integrate psychiatric care into overall medical care through MH interventions; such efforts should continue, particularly in emergencies but also through the training of general practitioners, if needed, in regular projects. Prospects for 2013 - The MH databases must be reviewed and data analysis improved in order to adapt better the MH strategies, but also to better document MH activities. Operational research could also be developed in the field of MH, for example on outcome measurements for beneficiaries of MH interventions. Towards this end, in collaboration with the Operational Research Unit, MH made connections with external contacts to provide technical support on this topic. - More human resources need to be allocated towards the implementation and supervision of MH activities. Many of the current positions of expatriate psychologists are not devoted full-time to psychology (e.g., the shared position of Field Coordinator and psychologist); others are mobile positions between projects or temporary short-term positions, neither of which permit sufficient support for the MH MEDICAL ACTIVITY REPORT 2012 19. mental health 58 professionals in the field. Ongoing training and supervision are mandatory to ensure quality MH care. MSF MEdical Department OCB Nutrition 1. Overview In the context of nutrition, 2012 was characterised by a political crisis in the Sahel region of Africa, accompanied by a food/nutritional crisis. In this context, OCB intervened in Mali, Mauritania and Niger. In addition, OCB also responded to the humanitarian crisis in South Sudan by providing medical care in the refugee camps in the region (cf. Emergency Unit section, §2.2.1.). An innovative approach, based on Mid-Upper Arm Circumference (MUAC)-for-height as admission criterion for therapeutic feeding centres, was introduced for management of acute malnutrition in children over five years of age in the refugee camps. For the regular programmes, the total numbers of beneficiaries was the lowest since 2008: the number of patients treated for Severe Acute Malnutrition (SAM) was lower than in 2010 and 2011, and in particular the number of patients with Moderate Acute Malnutrition (MAM) decreased dramatically. Additionally, this year there were no selective feeding distributions and decreased nutritional support to ill patients. As forecast previously (cf. Medical Activity Report 2010), the new project in the Kamrangirchar slum setting in Dhaka, Bangladesh has developed into a focus project for operational research into nutrition in general and nutritional approaches in Asia in particular. The first research publications from Bangladesh were released in 2012. 2.1. Activities at project and mission level During 2012, OCB conducted 22 nutritional projects across 13 countries (table 1). Most Table 1: OCB nutritional projects in 2012 Type of programme Countries and projects Nutrition main activity/emergencies DRC (Refugee Goma); Mauritania (Mbera Malian refugees, Assaba); Mali (Mopti, Douenza); South Sudan (Maban) Nutrition integrated into medical activities Afghanistan (Lashkar-Gah, Kabul); Bangladesh (Kamrangirchar); DRC (Masisi, Niangara, Lubutu); Ethiopia (Imey); India (Chhattisgarh); Niger (Dakoro, Guidan Roumdji); Sierra Leone (Bo); Somalia (Guriel); North Sudan (Darfur); South Sudan (Pibor, Gogrial) Nutrition integrated into HIV programmes DRC (Kinshasa); Guinea (Conakry, Gueckedou); Kenya (Nairobi); India (Mumbai) of the regular nutritional programmes were integrated programmes. Except for the emergency programmes in Mauritania, Mali and South Sudan, no new programmes were opened and two major ones were success- 59 2. Programme activities DRC: Democratic Republic of Congo fully handed over to the Ministry of Health months of age are now treated in the MSF lance through the nutrition international 2.2.1.1. Mauritania working group as well as a platform to share data and discuss strategies. All sections Since January 2012, the southern region of combined treated 142,251 SAM children in Hodh El Chargui received an influx of Malian seven countries compared to 124,990 (five refugees due to the conflict in northern Mali countries) in 2011. Comparing within coun- (cf. Emergency Unit section, §2.2.2.). In tries, Niger increased its number of benefi- March, nutritional activities started in the ciaries by 21% (and by 3% compared to camps (screening, ambulatory therapeutic 2.2. Nutritional Emergencies 2010, considered a “bad year”), Chad in- feeding centres (ATFC) and an inpatient ther- creased by 82% (but decreased by 23% apeutic feeding centre (ITFC)). Nutritional 2.2.1. Sahel compared to 2010), and Mali increased by surveys in June and November revealed high 7%. Burkina and Nigeria were much less af- levels of global acute malnutrition (GAM) (re- fected than 2011, with decreases of 62% for spectively 20% and 17%) and SAM (5.9% & both countries. However, with the exception 4.6%) with no improvement between the two of Niger, comparisons are not straightforward surveys despite food distribution and the as the number of projects differs within coun- presence of a nutrition programme. hospital) and to the national NGO BEFEN in Dakoro, Niger. Lashkar-Gah hospital (Helmand) with its therapeutic feeding programme in Afghanistan was handed over to OCA. From December 2011, alerts on a possible food crisis in the Sahel were raised. The international community and concerned governments set up action plans to mitigate the shock (general food distribution, targeted food distribution, subsidised cereal banks, etc.). MSF set up an intersectional surveil- tries. In the Assaba region, which was affected by food insecurity, support to MoH health struc- 20. nutrition intensive care cases and infants under six MEDICAL ACTIVITY REPORT 2012 (MoH) in Bo, Sierra Leone (only malnourished tures in five districts started for the management of SAM, with the secondary objective of surveillance of the situation in preparation for rapid response in case of a crisis, which for- Table 2: Number of OCB nutritional programmes in 2012 Type of programme No. of centres No. of patients admitted ITFC 20 total 18 integrated in hospital care 1 unknown 1 day-care 9,100 ATFC 67 total 66 integrated in hospital/HC 1 unknown 46,254 SFC + Selective Feeding (PLW) 4 298 + 3,831 Specific targeted nutritional support (sick patients) 4 612 tunately did not materialise. The proximity with the communities was a challenge in this context, impairing the efficacy of surveillance. 2.2.1.2. Mali OCB intervened in the conflict area (Mopti – Douentza) with support to primary health care (PHC), including the treatment of SAM ATFC: ambulatory therapeutic feeding centre; ITFC: intensive therapeutic feeding centre; NA: not available; PLW: pregnant and lactating women; SFC: supplementary feeding centre (cf. Emergency Unit section, §2.2.2.). 2.3. Nutrition Programmes 60 2.2.1.3. Niger The typical setup of OCB nutritional activities (1,790) compared to 4% in 2011; the decrease is due to the handover of the Dakoro Niger registered more patients in nutrition pro- consists of one ITFC for severe/complicated grammes than in 2009 and 2011. Admissions cases, several satellite ATFCs for uncompli- to the ATFCs were lower than in 2010 in the cated cases, and sometimes several Supple- first semester and similar in the second. How- mentary Feeding Centres (SFC) for moderate ever, the increase in ITFC admissions was cases. In addition, selective feeding (adapted dramatic, with a four to six fold increase from to the target population) is provided to vul- August to October, probably due to the over- nerable groups such as children under two lap of the malaria season with the malnutrition years of age or pregnant and lactating wom- Cure rates in TFP ranged from 8.4% in peak and the cessation of NGO support to en (PLW), and specific targeted nutritional Chhattisgarh (India) to 85.5% in Sudan (table Maradi hospital, draining people to Guidan support is provided for patients in vertical 4). Globally, most of the integrated projects Roumdji hospital. projects, such as HIV/tuberculosis (TB) pro- performed slightly less well than last year; grammes. An overview of all OCB nutrition only Sierra Leone stayed stable (with 83.7% activities is presented in table 2. compared to 83.3% the prior year). An 80% 2.2.2. South Sudan Nutritional interventions were done in the refugee camps in the Maban region. In the camps, particularly in Batil, the health status of the population was poor and the prevalence of malnutrition was high (GAM: 39.8%, SAM: 13.4%), even when measured by MUAC and oedema only (27.7% and 10% respectively). Children over five years of age, adolescents and adults (especially the elderly) were also affected and were included in the programme from September. Once included, this segment of the population represented 33.4% of the admissions. The prob- 20. nutrition represented 3.4% of the total beneficiaries Overall, OCB treated 60,095 patients in 2012, compared to 96,193 patients in 2011 (table 3). This represents the lowest number of patients treated since 2008. Except in one HIV project (Kenya), MAM was not treated and organized selective distributions did not occur. In the contexts where these programmes were pertinent (e.g. Niger, refugees in South-Sudan and Mauritania), these needs were covered by the World Food Program (WFP) and other NGOs. project in Niger in September. There are still large variations between projects: the top three projects are Bangladesh with 35.7% of infants, Sierra Leone with 26% (due to restriction of target population of the programme), and Afghanistan with 10%. cure rate was set as the target. Only two out of 15 (13.3%) programmes achieved this target (compared to 28.6% in 2011), while eight out of 15 (53.3%) even remained below 70%. Low cure rates were typically a consequence of high defaulter rates; similar to 2011, these rates of more than 15% were observed in nine out of 15 (60%) programmes, of which eight were above 20%. These defaulting rates are linked with mobile populations (India, Bangladesh and Mali), security problems (Pibor) or geographical access during the 2.3.1. Therapeutic Feeding Programmes rainy season (Gogrial). Unexpectedly, high defaulting was also observed in refugee set- lem could have been tackled earlier, raising In Therapeutic Feeding Programmes (TFP) tings (Maban in South Sudan and Maurita- the question of whether the elderly are a “ne- with both ATFC and ITFC components, the nia). In Mauritania, it was clearly linked with glected population” in this context. The role proportion of patients needing hospitalization acceptability of the programme by the Touar- of MSF for this vulnerable population in the ranged from 1.4% (Mauritania) to 46.1% (So- eg population and population movements in context of population displacement and rup- malia) in 2012 (table 4, Annex). The overall and out of the camp. After some investment ture of social networks and social structure admission of infants younger than six months of the team with the community health work- MEDICAL ACTIVITY REPORT 2012 needs to be discussed. A new protocol based on a simplified MidUpper Arm Circumference (MUAC)-for-height Table 3: Annual numbers of treated patients SAM MAM Selective feeding and sick patients Total 2008 51,349 54,774 734 106,857 years of age, but documentation/lessons 2009 42,947 21,677 7,442 72,066 learned could not yet be done. Questions 2010 55,324 4,127 65,500 124,951 were raised about the possibly overly restric- 2011 59,874 2,553 33,766 96,193 tive MUAC cut-off used for adults. This 2012 55,354 298 4,443 60,095 was introduced for the children over five should be investigated further. MAM: moderate acute malnutrition; SAM: severe acute malnutrition ers, the rate decreased from 40-60% to 25% - Nutritional and retrospective mortality sur- dren under five years of age. In 2012, the in December. In Mali the defaulter rate was veys were conducted in Mauritania (Mber- nutritional support for PLW switched to an high during the first three months of the pro- ra camp), Sierra Leone, and South Sudan adolescent clinic, with special focus on gramme, and then decreased gradually to (Pibor; Doro and Batil refugee camps in pregnant and lactating adolescents. The between 20 and 25% in October and No- Maban). Additionally, rapid nutrition and overall objective of this project is to expand vember and 5% in December. In Maban, the food security assessments were per- OCB knowledge and experience on urban yearly result is skewed by four months of formed in Afghanistan (Mukhtar camp), settings and on malnutrition in Asia, and to high defaulter rates; the rest of the year, this Mali (Koulikoro, Mara, Mopti), Mauritania advocate for the CMAM approach in Bang- rate varied between 4% and 12%. (Assaba), as well as active community ladesh. In 2012, the following research screening (MUAC + oedemas) in Niger, studies were completed and published: - “Weight evolution, morbidity and case and the Gondama Referral Centre (GRC) in - Field visits were performed to South Su- fatality among children assessed as be- Sierra Leone (14.2%). In the latter, this is to dan (twice) for support to the refugee ing severely malnourished by weight-for- be expected as the project focuses only in- emergency response. height (<-3 Z-score) criteria but not us- six months. HIV projects were not included in this comparative analysis. 2.3.2. Supplementary Feeding Programmes 3. Training ing mid-upper arm circumference (MUAC) in a slum setting in Dhaka, - Two sessions of the Nutrition E-learning Bangladesh” (with a poster presentation module, which is a tutorial shared with ref- at the MSF UK Scientific Day and an oral erents of OCA and OCBA, have been or- presentation at the OCB Operational ganised. The translation of the module to Research Day). This year, except in the HIV programme in French was finalised but due to technical Kenya, there were no Supplementary Feeding problems during importation on the Doke- Programmes (SFP). In some contexts, the os platform, two sessions were cancelled. SFP was covered by other NGO’s (e.g. refu- -Nutritional input was provided to other per on children accepted, one on PLW trainings, including the Populations in Pre- under peer review (with a poster presen- carious Situations course (PSP), the Man- tation at the MSF UK Scientific Day and agement of Health Services course (MHS), an oral presentation at the OCB Opera- the Logistics Coordinator Course (LCC). tional Research Day). gee emergencies) or by the MoH and the WFP (e.g. Niger). The one SFP in Kenya and Specific Targeted Nutritional Support activities are documented in tables 5 and 6 (Annex). 2.4. Operational Activities - “Acceptability of Plumpy-nut for community based therapeutic feeding in a slum setting in Dhaka, Bangladesh”: one pa- - A collaborative project with “Global Health - “Does the 65 cm height cut-off as age -Niger: In Guidan Roumdji the evolution of Media” was initiated for development of proxy exclude children eligible for nutri- the security situation jeopardised the su- training videos on nursing, hygiene and tional assessment in Bangladesh?” pervision of the programme. In 2012, the medical procedures in collaboration with malaria peak arrived one month earlier and the paediatric and hygiene referents. coincided with the malnutrition peak. The paediatric ward and ITFC were overloaded with patients (the admissions doubled 4. Operational Research and Developments - “Severe malnutrition in children presenting to health facilities in an urban slum in Bangladesh”. - The documentation on “Feasibility and compared to 2011: 4,240 versus 2,157). 4.1. Publications outcomes of a community based ap- During 17 weeks (from mid-August to mid- Several papers on the Bangladesh pro- nutrition among children <5 years in an November) more patients were admitted than during all of 2011 (2,528). This situation impacted the quality of care and the mortality during that period, which increased to 8.5 in September and 9.9% in October. In Dakoro, the handover of the gramme and one on the impact of water and sanitation on nutrition programme results in Niger were published over the course of 2012 (cf. Operational Research and Documentation section, §5.). project to the national NGO BEFEN, sup- 4.2. Ongoing Studies ported by the international NGO ALIMA, - The “Treatfood project”, aimed at evaluat- was completed in September. ing therapeutic approaches to MAM, was proach to managing severe acute malurban slum setting in Dhaka, Bangladesh” is still ongoing. - In South Sudan, sitting height was measured in two nutritional surveys to calculate the Sitting-Standing-height ratio to evaluate influence of body shape on the weightfor-height index, but preliminary analyses were not conclusive. - Sierra Leone: MSF support to the ITFC, abandoned in its current form because of which was already transferred to the dis- the lack of an available setting to conduct trict hospital, stopped in the beginning of the study – planning of a revised project is The revision of a number of nutritional tools the year. The Intensive Care Unit providing ongoing. and guidelines continued in 2012: care for malnourished children with severe complications, and the infant ward for infants younger than 6 months remained in the GRC. -Bangladesh: operational research in this setting continued (cf. §4.2.). - As mentioned, the project in an urban slum 4.3. Tools and Guidelines - The release of the “Nutrition Pocket setting in Dhaka, Bangladesh had a sizea- Guide” has been delayed due to shifts in ble operational research component (cf. human resource. §2.4.). This project focuses on Community 61 tensive care cases and infants younger than 20. nutrition grammes, except in Niangara, DRC (7.1%) during the hunger gap season. - The revisions to the Nutrition guidelines Management of Severe Acute Malnutrition are still ongoing in collaboration with the (CMAM) and primary health care for chil- Nutrition intersectional working group. MEDICAL ACTIVITY REPORT 2012 Mortality rates remained below 5% in all pro- 5. Looking back and ahead Lessons learned for 2012 - In 2012 the Nutrition unit was again confronted by human resource gaps. As a consequence, some projects were delayed, as priority was given to the emergencies. - Results of the Bangladesh operational research on admission criteria confirm that in Asia, it might be safe to use MUAC and oedema only as admission criteria to nutritional programmes. This study should be repeated in African contexts. - A new focus was placed on malnutrition in children over five years of age during the emergency in South Sudan. This crisis highlighted the need for paying more attention to other vulnerable groups, especially the elderly, in emergencies. During the previous years the focus was mainly on children below three years of age. Prospects for 2013 - The admission criteria (especially MUAC) to TFP in African contexts and the influence of body shape on weight-for-height index will continue to be explored. - Access to proper vaccines will be improved, as detailed in the Expanded Programmes of Immunisation (EPI) in nutrition programmes. - The management of infants less than six months old (including neonates) will be improved, and in collaboration with the Paediatrics and Sexual and Reproductive Health (SRH) referents, support to breastfeeding in nutrition programmes (at the ITFC and ATFC level) will be further developed. The breastfeeding protocol will be revised and breastfeeding support strategies will be discussed. - A pilot project on CMAM will be launched and documented in Niger. - The OCB experience on management of adolescents and adults should be expanded and work should be done on admission criteria if an opportunity arises in emergencies. A standard protocol for nutrition support in PLW will be developed. MEDICAL ACTIVITY REPORT 2012 20. nutrition 62 - At the level of trainings, the first sessions of the E-learning in French will be completed and the content of the nutrition trainings will be revised to be in line with the international nutrition guideline when the latter will be published. Training videos will be developed on nursing, hygiene and medical procedures. MSF MEdical Department OCB Operational Research & Documentation 1. Overview A number of achievements were made over the course of 2012. These included: diversification of the Operational Research (OR) agenda and scientific publications following the re-allocation of responsibility of HIV/tuberculosis (TB) to the Southern Africa Medical Unit (SAMU) and non-HIV/TB research to the Luxembourg OR unit (LuxOR). The numbers of publications reached a new all-time high at 81 articles in peer-reviewed journals, to a large extent due to the success of the ongoing OR courses. Several original articles and viewpoints made an influence on policy and practice, including influencing the direction of the 2013 World Health Report, which is focused on research for universal health. 2012 also saw the completion of the first MSF-led OR course in Luxembourg (initiated in 2011), and the launching of two new courses managed by MSF, in Europe and in Africa. Excellent outcomes were achieved for all these courses, with 88% of the participants meeting all their milestones, and a 12-month and 24-month publication success rate of 77% and 93% respectively. These courses have now been accredited by the World Health Organisation (WHO) and will lead to a strategic WHO umbrella initiative to promote and catalyse the model globally. 63 An important milestone over the course of 2012 was the organisation of the first OR day by OCB in conjunction with the General Assembly. Oral and poster presentations were held in four broad domains: the day was well-attended and was considered a great success. This event will continue in a yearly fashion, to be attended by MSF members, external scientists and partners as a forum for dissemination of MSF work. further, with SAMU being the primary focus for all research on HIV/TB-related subjects (cf. HIV/Tuberculosis section) and LuxOR providing support to research on all other ac- Launch of the MSF OR courses Creation of the LuxOR unit 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 tivities of OCB, including capacity building in various areas linked to the operational pros- provided by the OR courses, which were ex- covered 15 broad topics, representative of pects. This diversification into non-HIV/TB- panded significantly over the course of 2012 most medical activities conducted by OCB related subjects was facilitated through site (cf. §4.): of the approximately 72 study proto- (cf. §5. & fig. 2) – domains which remained visits, including new visits to Egypt and DRC cols developed over the course of 2012, 48 underrepresented included mental health, to identify new areas of research (mental (66%) were designed in the context of the health promotion and infection control, and health, sexual and reproductive health, vac- OR courses. This highlights the vital impor- expansion of OR to these topics is foreseen in cination, neglected diseases, sexual vio- tance of these courses in bringing research 2013. As was done in previous years, book- lence), follow-up visits to Burundi and Sierra to areas where it is lacking and for diversify- lets (hard copy and CD) of all peer-reviewed Leone to consolidate existing research initia- ing knowledge. OCB publications were compiled and distrib- tives, and opening of a consultancy-based microbiologist position in Lashkar-Gah (Hel- uted to missions, partner sections, donors 2.2. Scientific publications and collaborating institutes. on antibiotic resistance (cf. Laboratory sec- A marked increase was observed in peer-re- tion, §4.). A site visit to Niger to develop the viewed OCB-related publications, from 52 in 2.3. Research dissemination research portfolio on nutrition was planned 2011 to 81 in 2012 (fig. 1), also due to the Dissemination of research findings beyond for 2012, but was cancelled due to security success of the OR courses which were initi- the scientific manuscript stage, and the constraints. Another important contribution ated in MSF in 2011 and expanded over the translation of such findings into policy and to the broadening of the OR agenda was course of 2012 (cf. §4.). These publications practice is one of the main goals of OR. Over mand), Afghanistan, for the first OCB study 21. Operational Research and Documentation The OR portfolio was successfully diversified 90 80 70 60 50 40 30 20 10 0 MEDICAL ACTIVITY REPORT 2012 2.1. Diversification of the OR agenda Figure 1: OCB-related publications by year up until 2012 No. of publications 2. Programme activities ular. Within MSF, the first OR newsletter was Figure 2: OCB-related publication themes in 2012 (n=81) Hospitals 1% Surgery & Anaesthesia 1% circulated within OCB during 2012, and sevConflicts & Humanitarian Emergencies 4% eral articles on OR appeared in the Contact magazine. OR 11% The Public Health Action journal is an open Sexual & reproductive health 6% access journal that provides a home for opHealth policy 6% Drug Safety 4% erational research with a mission to provide health solutions for the poor in low- and middle-income countries. The journal is now Non-communicable diseases 9% Health systems & programme monitoring 12% Other infectious diseases 5% used by operational researchers world-wide and MSF collaborates closely with partners to support the journal. 2.4. Research impact Nutrition 4% For the first time, a methodology on how to Malaria 1% HIV 14% TB 11% systematically evaluate the impact of OR was published in The Lancet and entitled “Is operational research delivering the goods. Assess- HIV/TB 11% ing the journey to success in low income countries”. A specific template for such evaluations was developed for OCB, and a pilot the course of 2012, dissemination was LuxOR-organised medical conference in analysis of this approach was presented at the achieved through a number of channels in- Luxembourg. OR day in June. This pilot analysis indicated cluding: the operational research day conducted in Brussels; participation in conferences; the MSF field research website; specific press communications; a new oper- 64 ational research newsletter; and support for a journal dedicated to operational research – Public Health Action. These are described in 21. Operational Research and Documentation brief below. MSF Field Research website (www.fieldresearch.msf.org), which archives MSF-authored publications from over 100 journals and 35 publishing houses and makes them available free-of-charge. More than 30,000 MSF publications were downloaded from this website over the course of 2012, reflecting the One of the major dissemination activities in high demand for MSF scientific output and il- 2012 was the organisation of the first OCB lustrating the merit of open access publica- Operational Research day, in conjunction tion. The website was also directly linked from with the General Assembly. A total of 16 the MSF Luxembourg website, improving its presentations were made and 25 posters visibility. A recent collaboration with MSF New were displayed. The four main oral presenta- York has improved the timeliness of uploading tion slots and titles included Maternal and articles and the medical directors have ap- Child Health, Hospitals and Surgery, HIV and proved a streamlined policy of seeking pub- TB, and Neglected Field Research. It was lisher permission. considered a great success in terms of en- that OR performs relatively well in influencing MSF and national/international policy & practice (81% and 63% respectively), but improvement of programme performance is insufficiently documented (only observed in 30% of the cases) to fully assess the impact of OR. Although there are several examples, a few notable examples of research impact in 2012 included the study on reduction in maternal mortality in Burundi and Sierra Leone, which showed how the MSF model of providing obstetric care could rapidly reduce maternal mortality at district level to achieve the Millennium Development Goal 5. This study will be featured in the World Health Report 2013. An advocacy article on the need to change detrimental and judgemental language in tuberculosis published in the International hancing the credibility and perceived value of One OR study, on the reduction of maternal Journal of Tuberculosis and Lung Disease led OR in MSF, especially OCB, and served as mortality in Burundi and Sierra Leone, re- to a global survey by the WHO-Stop TB part- an excellent forum to promote and dissemi- ceived massive press attention: it became nership and has resulted in the development of nate operational research. It will henceforth the focus of an international documentary a specific handbook “guide” on TB language become a yearly event and will be attended and was associated with several press re- that will be released in 2013. Finally an editorial by MSF members, external scientists and leases and advocacy pieces. In addition, the on the need for research to impact policy on partners. European Commission Development Coop- the ground, published in Tropical Medicine & eration Directorate had a meeting with MSF International Health, influenced the direction of to discuss the subject. the World Health Report 2013. ternational conferences, such as the MSF UK At the level of OR visibility, a document outlin- Scientific Day in London, the International ing the vision, goal, strategies and outputs of 3. Medical Activity Report AIDS Society (IAS) meeting in Washington, the Union-MSF OR group was written up and The fourth edition of the annual OCB Medical the meeting of the International Union Against will be published over the course of 2013. Activity Report for 2011, covering 20 techni- Tuberculosis and Lung Disease in Kuala This document will be used for marketing cal domains, was completed and published. Lumpur, the Quetelet Chair on Adult mortality and fundraising for OR in general and for the Publication of the report was strategically and morbidity in Louvain-La-Neuve, and a support of the MSF-Union courses in partic- synchronised with the medical coordinator Additionally, a number of poster and oral MEDICAL ACTIVITY REPORT 2012 Another ongoing dissemination tool was the presentations were given at national and in- days, the OR day and the OCB general as- ment, 2) Data management and analysis, launched and should help long term retention sembly, in order to allow for timely integration and 3) Paper writing and data presentation. in MSF. By December 2012, four MSF fel- and inputs into the 2013 Operations pros- During 2012, LuxOR team members were lows had led 79 research projects and pro- pects and plans. Data collection from the involved in the first African MSF course (Ken- duced 28 publications, showing the value of field for this document was again synchro- ya), two European MSF courses (Paris and OR fellows in advancing and sustaining re- nised with the Typology data collection to Luxembourg), the Pacific Union course (Fiji), search in MSF. avoid double work in data compilation. and the Asian Union course (Nepal). 4. Training/Capacity building The outputs have been compelling, with six The MSF-Union completed courses and 69 participants. Six- modular training course in OR has been ex- ty one (88%) completed their milestones, 68 tended to four continents (Africa, Europe, submitted their papers to a peer reviewed Asia & the Pacific region) and has been fine- journal, of which 39 (57%) have been pub- tuned during 2012. This course, which has lished. In terms of cohort analysis, 12 month been deemed a “best practice” example by publication success is 27/35 (77%) and at 24 WHO, the IAS and the Global Fund, offers months, 13/14 (93%). These results have three practical training modules, covering 1) been published in the Public Health Action A full list of the 81 publications of 2012 is pro- Research questions and protocol develop- Journal. A fellowship programme has been vided in the Annex. unique output-oriented A specific MSF-Union alumni website has been developed and will be launched in 2013. This will bring together all the course students of the MSF-Union group in various continents and will serve to improve networks, alliances and advocacy, as well as assess impact on policy and practice. 5. List of publications 6. Looking back & ahead Lessons learned for 2012 - The modular OR course is highly successful, with large numbers of applications for each individual course and high rates of success for participants finishing the course. However, organisation of and facilitation at these courses represents a sizeable activities needs to be safeguarded. - High turnover of Medcos and staff from the Operations Department affect the sustainability of research studies. There were also misun- 65 portion of LuxOR staff members’ time, and a healthy balance between the course research work and field visits and other related OR derstandings due to lack of background knowledge on the purpose of specific OR initiatives. This was exacerbated by late requests for support and abrupt closures of projects where requests were made for documentation support. This will need closer collaboration between operations, the operational and medical departments. - The expansion of operational research to areas where there is no research culture and where no data monitoring systems exist is a major challenge and requires additional resources and dedicated time in 2013 and beyond. This may also require additional dedicated - The costs related to supporting open access publications are a problem. Most open access journals charge from between 1000 to 1500 US$ per article. In some cases, waivers have been obtained, allowing reduced or no costs for MSF, but the problems still persists. “Pooled funding” to support open access submissions is needed as well as advocacy for donors to create mechanisms that support open access publications. - There have been some difficulties with ethics approval for SAMU projects by the MSF ethics review board (ERB). Protocols not developed with LuxOR staff input have been channeled through LuxOR without their input. This has led to some misunderstandings, and a new procedure is proposed for 2013. Prospects for 2013 - A further streamlining of the ethics review procedure, which is sometimes perceived as arduous, is foreseen. Specifically, 21. Operational Research and Documentation human resources. course of 2013. MSF will set up for the first time an Institutional Ethics Review Board in India, which will be considered a national ethics committee and will facilitate all MSF related research in India. - Completion of two prospective non-HIV studies, on antibiotic resistance in Afghanistan and a risk factor analysis for typhoid fever in Kikwit, DRC, is scheduled for 2013. Other new themes to be added to the OR portfolio are emergency interventions and mental health. - An expansion of the LuxOR unit to other operational centres, most notably OCG, is foreseen: this should allow further diversification of the OR agenda and will build a stronger research network and optimise existing resources within MSF. In the same vein, enhanced collaborations with the Brazil Medical Unit (BraMU) is also on the agenda. MEDICAL ACTIVITY REPORT 2012 an exemption procedure for publication of data generated through surveys is being negotiated and is expected to be finalised over the - Further consolidation and expansion of the OR courses is foreseen. Two MSF-run courses will be organised in 2013: one in Ethiopia and one in Luxembourg. Support will also be provided to the Union courses in Paris and Nepal, and an alumni network for all participants of past and present courses will be launched. Additionally, following accreditation of the courses by WHO, a course according to the MSF-Union blueprint will be run in Estonia in 2013. A strategic consortium for promoting and supporting OR is being led by WHO under the umbrella of SORT-IT (Strategic Operational Research Training Initiative). MEDICAL ACTIVITY REPORT 2012 21. Operational Research and Documentation 66 - Following the success of the first OR day in 2012, it will be conducted again in 2013 conjunction with the General Assembly. MSF MEdical Department OCB Paediatric Care 1. Overview Although paediatric care concerns children from birth through adolescence, children under five years of age (referred to as under five’s in this report) are most at risk of disease and death and remain the primary target for intervention. OCB data confirm that malaria, lower respiratory tract infections (LRTI), diarrhoea and neonatal pathologies are the main causes of disease and death in children under five. Neonates constitute a particularly vulnerable population, accounting for 43 % of global under five mortality (WHO, 2012). Over the past decade, while the number of under five deaths worldwide has decreased, the proportion of under five deaths occurring during the first month of life (the neonatal period) has continued to increase. 2. Programme activities Figure 1: Disease profile in children < 5 in OCB OPD, 2012 2.1. Under five care 2.1.1. Under five outpatient care In 2012, 673,274 under five outpatient consultations were conducted in OCB projects, representing 37% of all outpatient department (OPD) consultations, a proportion 67 2012 was characterized by improved reporting on neonatal activities and a modest increase in focus on neonatal care in OCB. In 2012, neonatal conditions accounted for 10% of under five inpatient morbidity and 26% of under five inpatient mortality, a marked increase compared to prior years (when routine reporting was not yet implemented). Adapted equipment is gradually being introduced in the MSF International Technical Coordination (ITC) catalogue. A chapter on neonatal units was included in the OCB guideline “Planning and design of health facilities”; neonatal clinical guidelines are under revision. Several OCB projects have begun to focus more on the physical environment and human resource needs of these children, for instance in the Gondama Referral Centre (GRC - Sierra Leone), Burao (Somaliland), Guidan Roumdji (Niger), and Timergara (Pakistan). Malnutrition 1% Others 10% Urinary tract infections 1% Non bloody diarrhea 16% Trauma, wounds, burns 2% Eye diseases 4% Bloody diarrhea 1% Intestinal parasitosis 2% Skin infections 5% which has increased slightly from 35% since 2011. Roughly one third of all under five outpatient consultations occurred in Niger: 9% contributions in terms of volume of under five outpatient consultations were the emergency interventions in the Maban region of South Sudan (15% - cf. Emergency Unit section, §2.2.1.), outreach activities in Bo, Sierra Leo- Fever of unknown origin 1% URTI 20% ne (8%), the health centres and mobile clinics Detailed data were available for the projects portant contributor to morbidity outside of in Masisi, DRC (8%) and the OPD of Ahmad using the Epicentre tools and/or MINOS (cf. Africa. When only emergency department Shah Baba hospital in Kabul, Afghanistan Health Informatics section, §2.). In these pro- (ED) data were considered (6% of OPD data), (9%). Health centre support was discontin- jects, the disease profile for under five chil- accidental trauma, wounds and burns con- ued during 2012 in Bo, Sierra Leone, with the dren was similar to that of previous years: tributed 21% to overall morbidity. exception of the largest health centre in Gon- respiratory tract infections represented 39% dama, close to the hospital. A new project, of the reported morbidity (half of which were Concerning tuberculosis (TB), a total of 334 Abu Elian (Egypt), focusing exclusively on LRTI), followed by malaria (18%), non-bloody cases (0.1% of all morbidity) were suspected under five outpatient care opened in August diarrhoea (16%), skin infections (5%) and eye in under five children, showing that little 2012. diseases (4%) (fig. 1). Malaria was not an im- measurable improvement has been made in 22. Paediatric Care and 25% in Guidan Roumdji. Other important LRTI 19% Malaria 18% MEDICAL ACTIVITY REPORT 2012 in Dakoro, which was handed over in 2012, case detection and/or reporting of TB at the Figure 2: Main pathologies in children < 5 in OCB IPD, 2012 health centre level. Fever of unknown origin Non bloody diarrhoea 9% represented 1% of outpatient morbidity, and some of these cases may in fact represent Others 19% undiagnosed TB. Implementation of a symptom-based TB screening questionnaire needs to be systematised at health centre level. Non-communicable chronic diseases, including asthma, represented only 0.2 % of Lower respiratory tract infections 17% Malnutrition 1% Anaemia (clinical) 2% overall outpatient consultations, and 1% if ED only data were included. Kibera (Kenya) will pilot a project with a paediatric compo- Fever of unknown origin 1% Neonatal diseases 10% nent on outpatient management of chronic diseases (including sickle cell disease and epilepsy). 2.1.2. Under five inpatient care Measles 2% Surgical cases 1% Trauma, wounds, burns, accident 3% Septicemia 2% Severe Malaria 33% In 2012, 35,435 children under five were admitted to the inpatient services in 21 OCB projects, representing 48% of all admissions to Figure 3: Main causes of mortality in children < 5 in OCB IPD, 2012 the inpatient department (IPD), a proportion Non bloody diarrhoea 3% which has remained stable since 2011. Two projects, the GRC in Bo, Sierra Leone and Guidan Roumdji in Niger, represented half of Lower respiratory tract infections 12% Others 23% all under five admissions. Two other large paediatric projects (in terms of volume of inpatient activities) were handed over during the course 68 of 2012: Lashkar-Gah (Helmand), Afghanistan (handed over to OCA) and Dakoro, Niger Malnutrition 1% (handover to the NGO ALIMA). The decision Tuberculosis 1% was made not to open a new paediatric hospital in Juba, South Sudan. Severe Malaria 27% Data for the paediatric inpatient wards were aggregated for the projects using the Epicentre tools or MINOS. Severe malaria (33%), Neonatal diseases 26% LRTI (17 %), neonatal pathologies (10%), and Anaemia (clinical) 1% non-bloody diarrhoea (9%) were the leading Meningitis 1% under five exit diagnoses from OCB hospitals Septicaemia (suspicion) 5% (fig. 2). Data for severely malnourished children admitted to inpatient therapeutic feed- laria (27%), neonatal pathologies (26%), LRTI remains a considerable killer, and it is thus (12%), septicaemia (5%), and non-bloody essential to continue focusing on compre- diarrhoea (3%) (fig. 3). Suspected TB, menin- hensive care for children with severe malaria, The inpatient mortality rate for under five chil- gitis, clinical anaemia and malnutrition each including injectable artesunate, antibiotic dren discharged from paediatric wards was accounted for 1% of hospital mortality. CFR’s treatment in case of co-infection, appropriate 6.5% (target < 10%), the defaulter rate 3.3 for the main contributors to hospital mortality fluid management, feeding and nursing care %, and the transfer rate 3.1 %. Only three are reported in figure 4. for comatose children, and management of ing centres (ITFC) are reported elsewhere (cf. 22. Paediatric Care Nutrition section, §2.3.). projects had inpatient mortality rates exceeding 10% - Lashkar-Gah and Khost in Afghanistan and Kabezi in Burundi - although the MEDICAL ACTIVITY REPORT 2012 latter two projects include only neonates as under five population. In Lashkar-Gah, the proportional morbidity (41%) and case fatality rate (CFR - 34%) were especially high for neonates, confirming the need to target this population for intervention. Overall, severe malaria had a CFR of 6%, compared to published inpatient CFR’s usually exceeding 10 %. Although injectable artesunate was successfully implemented in the projects with the highest burden of severe malaria (Guidan Roumdji in Niger and the GRC in Sierra Leone), this relatively low CFR, which has remained unchanged since 2011, is likely attributable at least in part to complications (hypoglycaemia, seizures). Neonatal pathologies, the second leading cause of inpatient mortality in OCB projects after severe malaria, are discussed in more detail below (cf. §2.2.). Of note, the burden of malaria in the neonatal population remains poorly quantified in OCB projects. This should be improved in 2013. The five most important causes of hospital an over-diagnosis of severe malaria cases in LRTI were the third major cause of under five mortality in these projects were severe ma- our projects. Nevertheless, severe malaria inpatient mortality. Although the CFR for first time in 2012, neonatal diagnoses were Figure 4: Case fatality rates in children < 5 in OCB IPD, 2012 Meningitis systematically included in the IPD Epicentre 22.0 tools. 19.6 Septicaemia (suspicion) Tuberculosis 16.5 Overall, 75% of inpatient neonates in OCB 16.2 Neonatal diseases Malnutrition projects were discharged, 16% died in hos- 8.4 pital, 4% were referred, and 5% defaulted. 5.4 Severe Malaria Although no international benchmarks exist 4.4 "Lower respiratory tract infections to evaluate these results, the following tenta- 3.7 Anaemia (clinical) tive targets have been set by the Paediatric 2.0 Non bloody diarrhea 0 5 10 15 20 25 Working Group for inpatient neonatal mortality, based on a literature review and empirical LRTI was 4% overall, it ranged from 2% to Finally, meningitis, which also contributed 1% project data: 11 % (in the GRC, Sierra Leone). In projects to under five inpatient mortality, remains as- with a high CFR for pneumonia, some of the sociated with a high CFR of 22 %. Early sus- ≤ 10%: gold standard deaths attributed to LRTI could be due to picion and treatment are essential to de- underdiagnosed TB, although this can only crease the burden of mortality and morbidity be speculated. Generally, implementation of in these children. number of suspected TB cases on paediatric wards remains very low (0.3% of morbidity), while fever of unknown origin represents 1% of inpatient morbidities. Moreover, the diagnosis of TB is often made late, which is reflected by its high inpatient CFR of 17%. An additional challenge in paediatric inpatient settings (e.g. Lashkar-Gah, Guidan Roumdji, the GRC) is that children suspected of TB are referred to National TB Programmes, where treatment initiation or continuation cannot be guaranteed. Septicaemia and non-bloody diarrhoea were proximately one third of all deaths from malaria, pneumonia and diarrhoea. Malnutrition contributed to 1% of under five inpatient deaths in 2012, compared to 10 % in 2011. However, since data collection tools allow only a single diagnosis, it remains difficult to reliably interpret these results, and the true While one quarter of under five inpatient mortality in 2012 was due to neonatal pathologies, neonates were the leading cause of under five inpatient deaths in Martissant (Haiti), Burao (Somaliland), Masisi (DRC), Dakoro (Niger), and Lashkar-Gah (Helmand, Afghanistan), accounting for 48-64% of under five inpatient deaths in those projects. burden of deaths attributable to malnutrition Severe neonatal infections (34%), conditions in paediatric OCB projects (outside of ITFC) linked to preterm birth/low birth weight (29%), remains uncertain. The management of mal- and birth asphyxia (21%) were the main caus- nourished children is quite specific and, es of death in inpatient neonates (table 1). Al- therefore, screening of all children on paedi- though neonatal tetanus had the highest case atric wards for malnutrition is essential (cf. fatality rate (46%), it contributed only 4% to Medical Structures section, §2.3.1.). overall neonatal inpatient mortality. Three quarters of cases of neonatal tetanus were the fourth and fifth leading causes of under 2.2. Neonatal care five inpatient mortality, with CFRs of 20% and Data was analysed for the projects using the 2% respectively. Early recognition and man- Epitools, MINOS, or the individual neonatal agement of critical illness (including shock database (cf. Health Informatics section, Stratification of mortality data by birth weight and severe dehydration) remain essential. §2.3.). In terms of volume, 16% of all inpa- was possible by aggregating data from pro- Following the 2011 Fluid Expansion As Sup- tient neonatal activities took place in vertical jects that implemented an individualised neo- portive Therapy (FEAST) trial and a 2012 in- obstetric programmes (Khost, Kabezi), 12% natal database (Burundi, Niger, Sierra Leone, tersectional meeting with outside experts, in pure paediatric and nutrition programmes Afghanistan - fig. 5). Although extremely low fluid recommendations for children with without MSF obstetrical activities (Guidan birth weight (< 1,000 g) and very low birth shock and severe infection were revised. Roumdji) and 72% in integrated programmes weight (1,000-1,499 g) babies had very high These revised algorithms for malnourished (including obstetrical and other activities). inpatient mortality rates, 81% and 51% re- and non-malnourished children should be Overall, 61% of inpatient neonates were ad- spectively, they represented only 1% and 6% fully implemented in 2013. mitted from MSF health structures, 21% from of neonatal inpatient admissions (data not home, and 18 % from other health struc- shown). Clinical anaemia contributed 1% to overall mortality in OCB projects, with a CFR of 4%. Haemoglobinopathies, in particular sickle cell disease, although not a part of routine data collection, are increasingly being reported as problems in specific projects, such as Guidan 69 be strengthened in OCB projects. The total Globally, malnutrition is associated with ap- > 20%: to be improved tures. Based on data from projects with maternal programmes, 12% (for GRC, Masisi, and Khost) to 22 % (Burundi) of neonates born in MSF health structures required inpatient admission because of complications. reported in a single project, Lashkar-Gah (Afghanistan), where 46% of neonatal admissions were home deliveries. 22. Paediatric Care dren (such as clinical algorithms) needs to 16-20%: acceptable For babies < 1,000 g, technological limitations (e.g. lack of ventilator support) are an important factor explaining the high mortality. Considering current resource- and technological limitations in OCB projects, successful out- Roumdji and the GRC. Improved inpatient Neonatal pathologies as a proportion of un- comes are rare in this category of neonates. protocols for these children will be developed der five IPD morbidities increased from 5% in Individual projects (e.g. the GRC) have started in 2013. Specific data collection could also 2011 to 10% in 2012 (with peaks of 29% in to implement a supportive, non-invasive ap- help better define the burden of disease in in- Masisi and 22 % in Ahmad Shah Baba). This proach for these babies, including special at- dividual OCB projects. is primarily due to better reporting. For the tention to counselling of mothers. For the very MEDICAL ACTIVITY REPORT 2012 tools to improve the diagnosis of TB in chil- 11-15%: good low birth weight babies (< 1,500 g), care re- Table 1: Neonatal causes of mortality and case fatality rates in OCB IPD, 2012 mains intensive in terms of human resources, Proportional mortality Case fatality rate Severe neonatal infections 34% 12% Conditions linked to preterm birth/low birth weight 29% 25% Birth asphyxia 21% 18% approach whereby gestational age (although Neonatal tetanus 4% 46% not always simple to assess) is also taken into Congenital malformations 4% 22% Other neonatal diseases 8% 11% and the capacity to implement inpatient care for these babies may not be present in all contexts. This does not exclude a case-by-case consideration. Among low birth weight babies (1,500 g-2,499 g) and those with a birth weight ≥ 2,500 g, data show that relatively good out- Figure 5: Neonatal inpatient mortality stratified by birth weight in OCB IPD, 2012 0,9 0,8 0,7 0,6 0,5 0,4 0,3 0,2 0,1 0 comes can be achieved with the available 81% means. This supports the implementation of a minimum package of neonatal care in all pro- 50% jects for neonates ≥ 1,500 g. The minimum 17% 21% 11% package of neonatal care, as well as different levels of care according to different contexts, were discussed in 2012 and will be refined in < 1000 g 1000- 1499 g 1500- 2499 g > 2500 g Neonates with an unknown birth weight represented 3.6 % of all inpatient neonates. BW: birth weight Unknown weight 2013 in collaboration with the Sexual and Reproductive Health referents. 3. Looking back and ahead Lessons learned for 2012 70 - Neonatal lives can be saved with limited technology. However, physical space and dedicated trained human resources in sufficient numbers are essential. - The Kabezi project in Burundi (to be closed in 2013) set a very good model for linking maternal and neonatal care. In emergency obstetrical programmes, there is a need to think about neonatal services from the outset, since 10- 20% of babies may need inpatient care. - The package of neonatal care cannot always be linked to the package of maternal care since neonates born at home or in other health structures are also seen in our paediatric programmes. Prospects for 2013 The priorities in 2013 will be: - A sustained focus on improving neonatal care, since neonates are contributing significantly to morbidity and mortality in OCB projects. 22. Paediatric Care - Further defining different levels of neonatal care according to the context, a minimum package of neonatal care and the limitations of neonatal care. - Improving data collection in OPD and emergency settings, so that appropriate and targeted interventions can be implemented (suggested). Other activities will include: - Improving the quality of OCB paediatric care through a transversal approach, focusing on the main causes of morbidity MEDICAL ACTIVITY REPORT 2012 and mortality in children. - Increased attention to nursing care, hospital hygiene, and hospital management in hospital settings, and scaling up the level of emergency and intensive care in the GRC, Sierra Leone. - Support to other disciplines, such as for the implementation of TB diagnostic tools and for routine and catch-up vaccination in under five programmes. - Opening of a comprehensive health care project in DRC (with primary and secondary health care components), which is expected to have a significant volume of under five activities. MSF MEdical Department OCB Pharmacy 1. Overview The emergencies in Syria and South Sudan and the increased activities in countries with import constraints such as Ukraine, Afghanistan, Pakistan and India continued representing significant challenges to the medical supply chain. The complexity of the global pharmaceutical market and the evolving regulations in developing countries remained the main challenges and have forced MSF to specialize its supply chain to the specificity of each context and also to interact more closely with the National Drug Regulatory Authorities (NDRA). Support to the medical and logistic teams on quality monitoring, rational medical procurement, and data quality continued and improved in 2012. At a logistical level, annual medical forecasts and order chronograms were pooled for all missions, allowing anticipation of global needs and facilitating the medical procurement flow. Standardisation of the essential medicines lists and matching overall needs with procurement forecasts at the central level by MSF Supply (one of the three European procurement centres) can now be done with the help of an online webtool called “the Portal”. Appropriate selection, procurement and distribution are necessary precursors to the rational use of medicines. 71 Major changes occurred at supply level with the move of the MSF Supply site from Merchtem to NederOver-Heembeek, the start of the new Supply Unit under a unique Supply & Logistics Support Director, contributing to the restructuring of MSF Supply departments, and the creation of a Supply Chain director position. 2. The MSF Quality Assurance Scheme Table 2: Number of new inclusions of medical articles in the MSF list of essential medicines (2009-2012) New inclusions 2.1. Updates of the MSF medical list Type of articles Each year, the typology of procured medicines, which overlaps and is published in tandem with the standardised protocols of the 2009 2010 2011 2012 Drugs 11 9 12 48 Medical Supplies & Equipment 13 22 23 1 Total 103 48 45 49 2.2. Identification and validation of drug sources Fifteen products have been validated by MSF pharmacists in 2012 (table 3). Also in 2012, two exceptional validations were given by the Medical Directors - one for Streptomycin sulfate (1 g, powder, vial) and one for Paramomycin. Reporting on local procurement has Clinical Guideline, is updated according to World Health Organisation (WHO) Essential Medicines List (EML) (table 1 & 2). Some key new inclusions in 2012 were: - Midazolam, 1 mg/ml, 5 ml amp - Antiretrovirals: Darunavir 300 mg tab, etravirine 100 mg tab, raltegravir 400 mg tab, dispersible tablets for paediatric use Table 3: Number of drug dossiers approved (2008 - 2012) Drug dossiers approved Validation route 2008 2009 2010 2011 2012 MSF full product assessment 28 15 25 20 15 WHO pre-qualification 61 28 35 35 48 Medical Director Waiver* 1 1 0 6 2 * Exceptional approval based on risk/ benefit analysis. WHO: World Health Organisation (ABC/3TC and AZT/3TC) 23. Pharmacy new protocols, specific field needs, and the - TB drugs: linezolid 600 mg coated tab (re- Table 1: Number of new codes created for medical articles in the MSF list of essential medicines (2006-2012) Type of articles New codes created 2006 2007 2008 2009 2010 2011 2012 Number of active medical codes in 2012 Number of codes de-activated in 2012 Drugs 98 115 137 106 41 75 52 610 24 Medical Supplies & Equipment 146 185 404 224 236 141 215 1,686 64 Total 244 300 541 330 277 305 267 2,296 88 MEDICAL ACTIVITY REPORT 2012 served for drug-resistant TB) Figure 1: Medical procurement typologies in OCB missions 2.8% 6.4% 0.1% 3.5% 1.5% 0.6% 2.5% 4.8% 10.1% 1.6% 1.6% 3.5% 0.2% 0.1 % 0.8% 5.8% 16.3% 4.7% 4.8% 2.4% 0.3% 1.1% International 2.1% 20.3% International with constraints 1.6% 1.1% Mixed supply with MoH Local improved, though it still remains underreported in some countries. The risk/benefit evalu- 72 ation of local procurement and final approval too often rely on scarce evidence and information. 2.3. Alerts on quality and the awakening voice of local markets In 2012 two batch recalls and seven quality alerts of medical items were issued by the Table 5: Evaluation of local pharmaceutical market (2010 - 2012) Year Number of manufacturers approved Number of wholesalers approved Number of countries evaluated 2010 5 28 14 2011 6 11 9 2012 14 69 12 ing surveillance systems. This could be im- countries (Mexico, Lebanon, Pakistan, Tur- proved with a wider presence of pharmacists key, Iran and Iraq), 14 manufacturers were in MSF missions. approved, and 69 wholesalers were approved in the 12 visited countries (including MSF-European procurement centres concerning OCB projects (table 4). the aforementioned countries, and: Russia, Table 4: Number of quality related communications (2010 - 2012) Evidence of problems was reported for products marketed in highly regulated countries and also for products purchased locally. The 23. Pharmacy need for local medicine procurement in coun- Number of communications 2010 2011 2012 portation constraints, rather than an overall Quality alert 3 4 7 improvement of the pharmaceutical market. tries where MSF cannot import or faces im- mission pharmacists in OCB missions, the Batch recall 3 3 2 reporting of quality problems has slightly in- Total 6 7 9 creased for internationally and locally pro- 3. Medical procurement MEDICAL ACTIVITY REPORT 2012 two complaints from the field resulted in an MSF recall. Considering the weaker regulations applied to pharmaceutical production and distribution in In 2012, 19 out of 29 missions dealt with challenging medical procurement systems: for seven missions the medical procurement cured medical items. Regarding the quality complaints concerning all five MSF sections, South Africa) (table 5). These visits reflect the Quality related communications silence from the field on this topic is still worrisome, but with an increasing presence of Ethiopia, Myanmar, Zimbabwe, Lesotho and 3.1. Enforcement of legislation increases procurement workloads relied on the local market, five received part of their medicines from the public distribution flow and seven others faced difficult importation rules, leading to sporadic local purchases (fig. 1). In countries where local purchase was unavoidable, the unreliability of the local resource-poor settings, quality monitoring/ The year 2012 was very demanding in terms pharmaceutical market complicated the sup- pharmacovigilance procedures must be en- of assessment of local markets. An evalua- ply and led to a heavy workload, in particular forced at all levels of the medicine’s life cycle, tion of the local pharmaceutical market was as the enforcement of the quality of medi- particularly in countries that lack post-market- conducted in 12 countries. In six of these cines on the local markets is typically out- paced by the regulations enforced by the NDRA on medical humanitarian organisations such as MSF. Overall, for an increasing proportion of medicines, MSF cannot guar- Table 6: OCB Total Medical Expenditures in 2011 and 2012 Medical items OCB Total Medical Expenditure (M€) 2011 2012 Medicines 14.0 12.4 Vaccines 0.9 0.6 Small medical supplies 6.3 4.0 centres. The quality of medicines cannot be Medical equipment 2.3 2.7 assessed at the product level in the field, and Medical kits 1.9 2.4 therefore securing the supply chain through Total 25.4 22.1 antee the quality of the medical items purchased in the local markets to the same level as the ones from the European procurement international procurement will remain the pri- - Improved centralisation of information on local purchases less than in 2011 (table 6). An additional 1,6 M€ was spent on therapeutic food, mainly in South Sudan and DRC. 3.3. Need for collaboration with the NDRA The development of pharmaceutical regulations in developing countries, while in princi- A mere five out of 26 missions were respon- ple a positive change, is increasingly gener- sible for 59% of the total expenditure of med- ating importation constraints, with NDRAs icines (fig. 2): DRC as the second largest enforcing regulations which previously did OCB operation, Guinea and Zimbabwe for not apply to MSF. However, the NDRAs in programme ARV’s and gap filling of the pub- developing countries are not yet able to en- - Developing methods for easier local pro- lic distribution system, Ukraine for the DR-TB force international standards of quality and curement with higher quality assurance, programme and South Sudan for the emer- the same stringency to the local market, such as better practices of visual inspec- gency intervention together with the running which remains relatively unlegislated, leading tion at reception and quality monitoring projects. to increased risks on local purchases (cf. - Enhanced intersectional collaboration on local procurement through mutual procurement activities and increased numbers of intersectional pharmacy positions §3.1). Moreover, national laboratories often along the medicine shelf-life - Integrated pharmacovigilance practices as a standard activity in each project Figure 2: Top 5 countries in terms of medicines procurement expenditures in 2012 activities, and much MSF time and resources were devoted to counter-analyses while 20% - Increased capacity both to negotiate with NDRAs and to track the local regulatory lack capacities and budget for quality control Zimbabwe 42% DRC environment through country pharmacists batches of medication were quarantined, resulting in shortages at field level. Guinea The negotiation space at country level is usu- Ukraine ally limited. While collaborations with some In 2012, 18 missions purchased medicines South Sudan NDRAs over the past few years proved to be locally: one mission is in a highly regulated Others effective in facilitating the inflow of quality (cf. §3.3). 16% country (Italy), seven missions have a database implemented (Lebanon, Bangladesh, 6% 6% 10% medicines, thus assuring uninterrupted treatments for OCB patients, procurement of Ethiopia, India, Kenya, Pakistan and Ukraine), medicines was excessively time-consuming three missions have sent the validation form in 2012 for countries such as Zimbabwe, Af- (Afghanistan, DRC and Zimbabwe) and seven missions have purchased locally without any recommendation regarding quality (Bahrain, Egypt, Haiti, Mozambique, South Africa, Lesotho and Turkey). The validation forms to approve local purchases have been sent to The top 5 items of the medical procurement list were responsible for almost 16% of the total expenditure of MSF Supply turnover in the families Drugs, Equipment and Medical Supplies ( 20 M€ ) (table 7). ghanistan, Pakistan, Ukraine, India, North Sudan, and Ethiopia. Pharmacists from HQ had set areas of collaboration with the NDRA during field assessments, but there is a need to monitor the evolution of importation requirements and, if necessary, to maintain col- the missions and were used, and a checklist laborations. Intersectional pharmacist posi- for reception control should be implemented tions have played an important role in in 2013 together with the Standard Opera- supporting the operations to identify possible tion Procedure (SOP) – Local Purchase. Also in 2013, a pharmacovigilance scheme should be implemented in MSF projects. 3.2. MSF expenditure The total expenditure for OCB medical procurement (medicines, vaccines, small medical supplies, medical equipment and medical kits) in 2012 was 22.1 M€, of which 18.2 M€ were procured through MSF Supply. This 73 through: amount represents approximately 3.3 M€ Table 7: Top 5 items covering almost 16 % of the MSF Supply turnover of the families Drugs, Equipment and Medical Supplies Item Tenofovir 300 mg/ Lamivudine 300 mg/ Efavirenz 600 mg, tab Expenditure € Percentage 1,275,049 6% Lamiv (3TC) 150mg / Zidov (AZT) 300mg / Nevir (NVP) 200mg tab 711,608 4% Test, Malaria HRP-2, rapid (SD BIOLINE), 1 test 561,025 3% Vaccine Meningitis multidose, 1 dose, fl. 361,075 2% Amoxicilline, 250 mg, tab 280,645 1% 23. Pharmacy its medical accountability for local purchases MEDICAL ACTIVITY REPORT 2012 ority. Additionally, MSF has started to enforce solutions for difficult countries, such as India, The global responsibility over the entire sup- given to the pharmacist to work in the end- North Sudan, Kenya, and Ethiopia. The im- ply chain will fall under the new Supply Unit, user units and a better dynamic in stock portation constraint remains in Pakistan and implying a handover of responsibility and the analysis due to the fact that two different de- the Intersectional Pharmacist position is ex- up-scaling of the quality levels where it is the partments had to commit mutually on data pected to be created in 2013. most vulnerable (capital and project). This in- reporting and decision making. A complete cludes defining and designing a supply strat- assessment on the impact of the integration egy per project. In order to reach these goals, on administrative and technical management new positions were opened: three Supply activities in DRC is planned in 2013. Additionally, it is imperative that the possibility of importation of medical items is assessed during exploratory missions and that all new project plans include medicine supply in their Memorandum of Understanding (MoU). 4. Rational Use of pharmaceuticals the good functioning of the project, and is defined by the nature of the product (without any notion of quantity). It is specific for every project and based on the type of activities Supply Medical (pharmacist). This latter posi- 6. Human resources of Good Distribution Practices (GDP), under 6.1. Pharmacy management positions the command of the Pharmacy and GDP Di- The general recognition that all missions rector of the Supply Unit. Standard supply should include a country pharmacist position key performance indicators (KPI) will be de- and/or a project pharmacy position (mostly fined and systematically collected on a for hospital project) is well established and monthly basis, and followed at field level. was fulfilled at 83%. Emergency interventions in 2012 showed that pharmacists were sys- and operational objectives. Starting in 2012, Courses on the standard medical stock man- all OCB missions/projects were asked to agement software were ongoing in 2012. The work on their Standard List, in coherence number of missions using the tools reached OCB missions counted a total of 65 staff in- with the preparation of the Annual Review of 89% compared to 75% in 2011 and 68% in volved in full time pharmacy positions, 55 of Operations. 2010. Isystock was utilized by 54% of the mis- which were occupied by qualified pharma- sions; Logistix by 29% and both tools by 4%. cists. Table 9 shows the distribution of quali- The increasing coverage could be tentatively fications by position. The Standard List consolidates the discussion between projects, coordination, and the cell on needs, and supports the consistent use of authorized clinical protocols, providing 74 tation Officers (MIO) Supply and one MIO tion will be mostly focused on implementation A Standard List is a list of items essential for explained by the systematic utilization of the tools at the occurrence of an emergency. tematically sent when emergencies occurred. 36 active expatriate OCB pharmacists, including 12 new recruits, were permanently in a comprehensive inventory of pharmaceuti- The user manual to collect stock indicators the field in 2012 (compared to 27 in 2011 cals required for the best practice manage- on Isystock was introduced in July 2012. The and 23 in 2010). 30% of those carried out ment of most acute and chronic diseases procedure for Logistix is still pending. Regret- more than one mission. The pharmacist’s encountered in the project. tably, only seven out of the 15 concerned pool included approximately 40 pharmacists. All OCB mission/projects’ Standard Lists, as missions presented their KPI, of which three Permanent recruitment is ongoing to ensure only partially. Although the following figures coverage with turnover. well as their annual forecasts (the quantification of the needs) are included in a tailored 23. Pharmacy Chain Officers SCO, three Mobile Implemen- are far from being representative of OCB mis- 6.2. Trainings on pharmacy management tool, called ‘the Portal’. sions, they give some indication on stock 5. Pharmacy management No new missions were integrated under the 2012 saw a new OCB end-to-end supply supply in term of stock management in 2012. chain with as main objectives ensuring ser- A quick evaluation was done in the four exist- vice and quality at all segments of the supply ing integrated countries (Bangladesh, Bu- chain for the benefits of OCB operations, op- rundi, DRC, and Sierra Leone), showing that timizing costs linked to the supply chain, the major difficulties were in getting skilled complying with ever growing (inter-)national staff, clarifying roles and responsibilities be- regulations and constraints, ensuring that tween all parties, and setting a proper com- A three-day workshop was organised in Jo- supply does not encounter a bottleneck, and munication flow. Fortunately, some added hannesburg, South Africa, from 26 to 28 adding value to operations at project level. value of integration was reported: more time February. The objective was to provide gen- value and expired drugs (table 8). The usual yearly drugs management courses continued to be provided in 2012 (intersection advanced pharma week hosted by OCG in English and with simultaneous translation in French, intersection supply and order management course at project level in French, Supply manager courses). MEDICAL ACTIVITY REPORT 2012 Table 8: Partial indicators reported in 2012 Indicators in euro Burundi DRC Mali Niger Pakistan South Sudan Zimbabwe All projects whole year All projects whole year All projects whole year All projects whole year All projects whole year Maban July-Dec Murambinda whole year Average Stock Value 118,106 2,366,976 335,053 431,746 927,657 645,173 912,241 5,736,952 Incoming Value* 236,212 3,392,837 434,053 1 228,186 860,141 945,296 2,177,764 9,274,489 Expiries Value / % 9,495 (4.0%) 166,961 (4.9%) 984 (0.2%) 8,536 (0.7%) 80,550 (9.4%) 11,048 (1.2%) 16,294 (0.7%) 293,868 (3.2%) * Incoming Value: denominator to calculate the proportion of expired drugs. DRC: Democratic Republic of Congo TOTAL cused on HIV-AIDS programmes and mixed Table 9: OCB full time pharmacy management positions in the field in 2013 Expatriate Staff supplies. The idea was to develop solutions/ National Staff Qualified Pharmacists Nurses Qualified Pharmacists Doctors/Nurses Mission level 10 0 11 2 Project level 8 0 14 7 Other positions (coaching/support), supply, stock manager) 6 0 6 1 Total 24 0 31 10 alternatives/methods adapted to specific situations. 13 participants with different backgrounds (pharmacist, medical and non medical), MSF staff, and Ministry of Health (MoH) staff attended, coming from South Africa, Lesotho, Malawi and Zimbabwe projects. The experience was successful and should be encouraged in the future. eral knowledge and to revise the procedures Good Pharmaceutical Practices in South Af- on drugs management in MSF along with the rica and context-related system, mainly fo- 7. Looking back and ahead Lessons learned for 2012 The growing complexities of the pharmaceutical markets and the changing legislative framework in many developing countries continued and have created an increasing workload not only for HQ pharmacists but also for field pharmacists. The reinforcement of MSF’s Quality Assurance Scheme for countries bound to local purchase has been implemented and improved with the creation or updating of the databases. The intersectional pharmacist positions have managed to coordinate the different MSF sections and to maintain coherence in the procurement policies and relations with the NDRA. Other challenges remained with the implementation of the intersectional procurement procedures (implemented in few countries) and improvement of the collaboration with the NDRA. The Transport Policy has been finalized and implemented at MSF Procurement Centre level. Collection of data on local purchases and donations has improved slightly, but still needs to be strengthened and implemented by all missions. There is an important and rewarding professional role for pharmacists beyond pharmaceutical product supply and management. The 75 However, collection of stock management indicators with reporting on losses was far from successful and will remain a major challenge. pharmaceutical product should be seen not as an end in itself- but rather as a means to an end. When medicines are used for the greatest possible benefit of each individual patient and the society as a whole, improvements in health as well as cost savings will result. Prospects for 2013 The lobbying for paediatric formulations better adapted to the needs of children in MSF settings should continue to be addressed in 2013. Medicines with only one source approved should continue to be addressed as well. The Pharmacovigilance and Bioequivalence policies are expected to be finalized and implemented in 2013. The Waste Management of Pharmaceuticals list is also expected to be finalized and implemented in 2013. The Transport Policy is expected to be fully implemented at field level over the course of 2013-2014. In order to standardize and increase the adherence by the missions, the Local Purchase SOP and Donation SOP are expected to be implemented in 2013. the most effective available, the safest possible, and convenient for the patient. By preventing or detecting and resolving drug-related problems that can lead to drug-related morbidity and mortality, and by promoting and contributing to the rational use of drugs, pharmaceutical services can make a unique contribution to the outcome of drug therapy and the quality of care. Pharmaceutical care cannot exist in isolation from other health care services. It must be provided in collaboration with patients, physicians, nurses and other health care 23. Pharmacy More attention should be drawn to the part of a pharmacist’s task that is to ensure that a patient’s drug therapy is appropriately indicated, raise the pharmacist’s level of responsibility, and will require philosophical, organizational and functional changes. Among its objectives, the new end-to-end approach of the supply chain will target the increase of the level of warehouse management in the field, in order to achieve a better stock level management, to guarantee a higher level of quality regarding premises and devices, and to raise awareness of safety issues. Another concern will be to define a strategy regarding the minimum standards to implement at the local and international level in order to ensure a high level of quality throughout distribution (in a broad sense), and to inform and train the different actors (down to project level) to the defined GDP standards. Lastly, added to the existing KPIs, new objective KPIs should be defined in order to ensure continuous improvement. The follow-up of those KPIs will allow the projects to assess their improvement and should ensure the positive evolution of the supply and the Supply Unit. MEDICAL ACTIVITY REPORT 2012 providers. Changing the focus of pharmacy practice from products and systems to ensuring the best drug therapy and patient safety will MSF MEdical Department OCB Sexual and Reproductive Health 1. Overview The total number of projects with one or more Sexual and Reproductive Health (SRH) components decreased from 46 projects in 2011 to 40 projects in 2012. An SRH component was implemented in three new projects and five emergency interventions. In parallel, a total of seven projects were closed, and a number of missions with a historically strong SRH component refocused their activities. This large number of project closures as well as reorientations of existing projects resulted in a decrease of the total number of projects and activities. However, missions already implementing SRH activities continued to increase their activities, and improvements of indicators such as coverage of postnatal care (PNC) and prevention of mother-to-child transmission (PMTCT) of HIV were noted. 2. Programme activities 2.1. Antenatal care The overall number of projects offering Antenatal Care (ANC) and total ANC consultations decreased in 2012 (table 1). This overall decrease in consultations was due to the clo- 76 sure of certain projects, the handover of others and underreporting. For example, while the Thyolo project in Malawi reported the largest number of ANC in 2011, this mission no longer offered the full ANC package to the women in 2012, as the project focus shifted to Prevention of Mother-to-Child Transmission of HIV (PMTCT) and away from regular SRH activities. A similar trend was observed for the Mavalane project in Mozambique. Data on women who received ANC and were MEDICAL ACTIVITY REPORT 2012 24. sexual and reproductive health tested for HIV can be found in the PMTCT section (cf. §2.9.). Despite the increase of ANC consultations in most of the projects offering ANC, providing adequate coverage (4 focused visits during pregnancy) remained challenging. Women tended to come late in pregnancy and many attended only one or two ANC consultations (reflected by the high ratio of first consultation to total consultations in table 1). projects (e.g. Abu Elian in Egypt and the Ma- mONC facility. Three hospital projects (in ban emergency in South Sudan, cf. Emer- Sierra Leone, Burundi and Pakistan) did not gency Unit section, §2.2.1.). However, some cover normal deliveries; rather, they man- gaps remain in the implementation of the aged complicated deliveries referred from the complete core package of ANC activities (as district health centres. In projects not offering documented in the “SRH core package of delivery, a referral system was in place for pa- activities in MSF projects” by the SRH inter- tients either to another MSF project, an NGO, national working group). For example, routine or a Ministry of Health (MoH) facility, with haemoglobin testing for first ANC visits is still MSF covering the costs. not implemented in all projects, and some Total deliveries decreased since 2011 (table activities such as partner tracing for syphilis and Sexual Transmitted Infections (STI) remain challenging. Systematic “test and treat” for malaria is not implemented in all countries; this remains especially challenging in non-endemic countries, particularly considering that some missions reported a concerning percentage of women testing positive for malaria (e.g. 37% in Sierra Leone and 39% in Niangara, DRC). 2). Here too, closure/reorientation of several missions contributed to this decrease, particularly the Thyolo mission in Malawi (which has reported an average of 20,000 deliveries a year since 2009). However, projects covering deliveries have tended to expand, reflecting the successful promotion of institutional deliveries. One of the strategies to promote institutional delivery has been the maternity waiting home (MWH), which brings women closer to the health facility and reduces the 2.2. Obstetrics geographical barrier at the end of their preg- A total of 27 projects performed deliveries in 2012. All these projects offered emergency obstetric care and 16 provided Caesarean sections and blood transfusions, rendering them Comprehensive Emergency Obstetric nancy. In 2012, this strategy was highly successful in Masisi. The Operational Research Unit plans to document the success of the Masisi MWH in 2013, in order to learn from this experience and promote the MWH strat- and Neonatal Care (CEmONC) projects. egy to the different missions and operations. Some projects provided only Basic Emer- The rates of stillbirths and low birth weights Similarly to 2011, the core package of ANC gency Obstetric and Neonatal Care (BE- varied significantly between the different pro- activities was foreseen at the start of new mONC) but had a referral system to a CE- jects. While context and epidemiological pro- Table 1: OCB ANC activities, 2007-2012 Number of projects offering ANC Number of consultations (total): Number of consultations (first visit): ANC: antenatal care 2007 2008 2009 2010 2011 2012 31 41 33 29 27 24 175,585 243,131 318,242 247,068 258,132 169,672 71,212 105,981 99,457 117,489 113,149 79,889 Table 2: OCB obstetrics activities, 2007-2012 Number of projects doing deliveries Number of deliveries 2007 2008 2009 2010 2011 2012 32 31 29 26 24 27 30,948 37,584 53,995 58,107 72,348 47,908 Number of projects with BEmONC 8 14 20 22 24 36 Number of projects with CEmONC 18 14 14 17 16 16 2,096 2,508 2,918 4,007 6,438 5,411* Number of Caesarean sections * Numbers differ from those reported in the Surgical Activities section (§2.5.): Caesarean sections from e.g. Cange, Haiti were not included here, as only the surgical intervention and not the full mother and child medical care is an OCB responsibility there. BEmONC: Basic Emergency Obstetric and Neonatal Care; CEmONC: Comprehensive Emergency Obstetric and Neonatal Care. Table 3: OCB postnatal activities, 2007-2012 Number of projects offering PNC Number of consultations done 2007 2008 2009 2010 2011 2012 17 26 20 24 21 23 8,675 17,631 29,625 21,489 21,680 18,985 2008 2009 2010 2011 2012 PNC: postnatal care 33 36 25 27 27 85,701 159,724 64,363 53,635 47,662 file of the country play a role, other SRH ser- in 2012. This may be in part due to the Mus- stayed stable this year (2,909 versus 2,995 in vices offered by MSF, the MoH or other lim culture, where women tend to stay at 2011), with closures and handover of several partners, and their quality, affect maternal and home 40 days after delivery; however, the projects being compensated by increases in neonatal morbidity and mortality. For exam- Dakoro project in Niger saw a high uptake of other programmes (such as Zimbabwe). ple, access to quality ANC (not provided in all PNC (3,206 PNC on 2,079 deliveries). These projects) is vital to the prevention of stillbirths numbers indicate, in the case of Niger, that and low birth-weight babies. either women tended to come back for the 2.6. Sexually transmitted infections second postnatal care visit after delivery, or As in previous years, collection of data on that women who have delivered at home consultations for sexually transmitted infec- come in for postnatal consultations. tions (STI) was challenging, due to limitations 2.3. Postnatal care Twenty-four projects offered PNC in 2012, an increase from the previous year. Despite this of the data collection tools and the fact that increase, there was a decrease in the overall 2.4. Family planning total PNC consultations (table 3), due in part Family planning (FP) consultations, offered in care (ANC, PNC, FP, vertical HIV projects, to underreporting of data, mainly in projects 27 projects, decreased slightly from 2011 etc.). 25,503 STI consultations were report- that closed and did not report on partial data (table 4), again due in part to closure of cer- ed this year; however, this is likely an under- (Nimba, Liberia; Tripoli, Libya; Malakand, Pa- tain projects during the year. Even in settings estimation. kistan; and Galgaduud, Somalia). such as Afghanistan where FP could be con- Fifteen projects that have been offering PNC since 2010 have seen gradual increases in activities. In some cases, the growth of project activities has been impressive. For example the Kamrangirchar project in Bangladesh showed an almost seven-fold increase in activities compared to 2011, and the Lashkar-Gah project in Helmand, Afghanistan has seen a four-fold increase of PNC activities since 2010. If PNC coverage is calculated using MSF-assisted deliveries as denominator, PNC uptake has increased from 19% in 2011 (840 PNC on 4,385 deliveries) STI treatment is provided at multiple levels of sidered a sensitive issue, FP coverage con- 2.7. Fistula repair tinued to expand this year. However, a num- Two fistula campaigns were implemented ber of emergency obstetric care projects during 2012: one in Masisi, DRC and one in offered no FP. This gap in services needs to Gogrial, South Sudan. The Gogrial mission be addressed, as every emergency obstetric successfully completed its first fistula cam- care project should in principle offer free FP paign, performing operations on 36 fistula to its beneficiaries. Overall, FP activities patients. During both campaigns an expat should be strengthened, particularly in pro- fistula surgeon and midwife were sent to jects with high Caesarean section rates, as support the field teams. women have a higher risk of dying during pregnancy after previous Caesarean section. 2.5. Sexual violence Additionally, the long-term holistic project in Burundi performed 486 surgical interventions, representing a significant increase in activities from the previous year. Along with to 27% in 2012 (1,431 PNC on 5,329 deliver- Care for victims of sexual violence (SV) was offering holistic care for obstetric fistula, this ies for projects reporting data across both offered in 22 projects, although only 16 pro- projects serves as a training centre for expa- years). In Afghanistan, the PNC uptake in- jects reported SV cases in the annual data triate surgeons on fistula repair (four sur- creased only slightly, from 6% in 2011 to 8% collection. The reported number of cases geons were trained over the course of 2012) 24. sexual and reproductive health Number of consultations done MEDICAL ACTIVITY REPORT 2012 Number of projects with family planning 77 Table 4: OCB family planning activities, 2008-2012 Table 5: OCB fistula repairs, 2007-2012 2007 2008 2009 2010 2011 2012 2 1 5 4 4 3 83 146 156 178 429 551 Number of projects offering surgical repair for fistula Fistula repairs done and as a centre for operational research on cline from last year. In India, abortion laws are - OCB hosted the Advanced Life Support in early non-surgical treatment of fistula with not restrictive; however, in certain regions Obstetrics (ALSO) training in Denmark urinary catheters. In total OCB provided 551 where sex before marriage is not permitted twice. surgical fistula repair interventions, a 28% in- due to religious/customary laws, national crease of activities from 2011 (table 5). Some doctors will only perform TPR for married interventions were performed as repeat/fol- women. low-up interventions, and the total number of MSF offers post-abortion care in a remarka- Cape Town, South Africa (cf. HIV/Tubercu- ble number of projects by ensuring that staff, losis section, §2.9.). women operated for fistula was 408 (cf. Surgical Activities section, §2.6.). 78 adolescents workshop that was hosted in - OCB provided one facilitator to the OCP age incomplete abortions or complications of fistula patients were referred to partner or- induced abortion. A total of 23 projects pro- ganisations. The implementation of system- vided post-abortion care to 5,031 patients. atic catheterisation after obstructed labour Nonetheless, the number of projects offering - SRH modules were included in the Prepa- remained challenging for various reasons. In post-abortion care should be higher, since all ration for Primary Departure (PPD) course some of the EmONC projects, the bed ca- BEmONC and CEmONC projects should be (twice), the Management of Health Servic- pacity was limited due to large volume of ac- able to offer this package of care. These sta- es (MHS) course (three times), the Basic tivities. This was exacerbated by the fact that tistics reflect the urgent need for access to Logistics Courses (BLoC, twice), the Pop- patients need to be admitted for a long peri- post-abortion care by all women of repro- ulation in Precarious Situation (PSP) od of time, in particular those who live at a ductive age. course (once), and the Health Promotion International Women’s Health training for coordinators. course (once). a limited bed capacity. 2.9. Prevention of motherto-child transmission of HIV The MSF SRH International Working group An overall total of 57,829 pregnant women tropical medicine were hosted at the Institute were tested for HIV in nine projects across of Tropical Medicine in Antwerp. which is a challenge for maternities that have had contracted a fistula expert to visit the different fistula projects in order to analyse and capitalise the MSF obstetric fistula care in the different OC’s. A report will be presented by seven missions. The uptake of HIV testing in pregnant women was high, ranging from 62% (in the Roma, Lesotho project) to 99% - The SRH theoretical and practical modules for midwives and nurses who are studying - The module on “the role of the midwife in developing countries” was hosted by OCB at the Union Professionnelle des Sages the working group in 2013. (in the Kabezi, Burundi project). In Burundi, 2.8. Safe abortion providing only emergency obstetrical care, - A presentation on “Urgent delivery, Mater- implying that women were tested for HIV dur- nal death: the avoidable crisis,” was host- ing labour. The perinatal HIV transmission ed by OCB during the “Sexual and Repro- rate and post-breastfeeding transmission ductive Health and Rights in Emergency, rate were 3% and 5% respectively. There from policy commitments to implementa- was an average PMTCT coverage of 83% tion” event, at the Belgian Humanitarian among all HIV positive women attending Aid Unit in Brussels. Unsafe abortions are responsible for a significant proportion of maternal morbidity and 24. sexual and reproductive health Reproductive Health for adolescents in the In Afghanistan, Ethiopia and Sierra Leone, substantial distance from the maternity, mortality (estimated at 13% of the global maternal mortality) for women in countries where access to safe abortion is limited. By providing comprehensive abortion care, the risk of maternal morbidity and mortality related to unsafe and incomplete abortions is reduced. The package of comprehensive abortion care includes termination of pregnancy on request (TPR), post-abortion care and family planning. PMTCT testing was implemented in a project ANC. For the Burundi mission, total PMTCT coverage was achieved: of the seven women testing positive during labour, all received treatment. Specific information on PMTCT in vertical HIV projects is provided in the HIV/ Tuberculosis section. in the MSF structure or through referral to a 3. Training and human resources partner organisation. Across these projects, - In 2012, two international SRH trainings 1,636 TPR were performed in 2012. As in were hosted, one in English by OCB and 2011, most of the TPR were performed in one in French by OCG. For the interna- Khayelitsha project, South Africa, where tional SRH training hosted by OCG, OCB abortion is legal. The Nagaland project in In- provided three facilitators to support the dia has the second highest number of TPR three days of the training. TPR was provided in 13 projects, either withMEDICAL ACTIVITY REPORT 2012 drugs and equipment are available to man- - OCB facilitated the module on Sexual and done, although there was a considerable de- Femmes Belges (UPSFB). - A presentation of the CURGO project, Burundi, was given at the event organised around Mother’s Day, related to “Are we achieving Millennium Development Goals 4 and 5?” organised by the International Centre for Reproductive Health (ICRH) in Ghent, Belgium. 4. New developments and innovations -Finalisation of the International Cervical Cancer policy paper, by the SRH International Working Group. - Finalisation of the “Urinary tract infection in pregnancy” protocol. - Translation of the SRH logical framework mented in emergency settings, but very - In 2011, it was noted that the high work- and indicator list into French and updating few SRH tools have been adapted to load of midwives compromises the quality of the PMTCT indicators. emergencies. Thus an SRH in emergen- of SRH care and leaves little time for the cies toolkit has been developed. implementation of the vast number of rec- -Finalisation of the “ALSO Memento” adapted to MSF field settings. This me- - An SRH individual electronic patient regis- mento was created in order to start the ter database has been designed, and was decentralisation of the ALSO training in the sent for piloting to Khost (Afghanistan), field in 2012. Timergara (Pakistan) and the Gondama - The video for the use of Ultrasound in MSF Gynaecology and Obstetric programmes was finalised. Additionally, two powerpoints (on basic ultrasound and ultrasound after 20 weeks) for training have been made. These tools are aimed at producing a complete ultrasound training toolkit. - As highlighted in the 2011 SRH activity report, SRH activities are increasingly imple- Referral Centre, Bo (Sierra Leone). ommendations provided during site visits. To address this issue, support midwives, and provide coordination in the field, the Mobile Implementation Officer (MIO) Midwife position was created in 2011. This MIO position supported and trained first - The emergency obstetric care projects in mission midwives in the projects of Burao Burundi and Sierra Leone were the subject (Somaliland), Batil (Maban emergency, of an operational research study and sub- South Sudan, cf. Emergency Unit section, sequent large-scale press release, leading §2.2.1.), Timergara and Karachi (Pakistan) to much attention for the role of MSF in and Kabul (Afghanistan). reduction of maternal mortality (cf. Operational Research & Documentation section, §2.3.). 5. Looking back and ahead Lessons learned for 2012 - The MIO Midwife position was highly successful and performed a large number of site visits, which were well received. - The strategy for collaboration with traditional birth attendants is not harmonised across missions, but is left to the discretion - Guidelines on implementation of MWHs are urgently needed. 79 of the different coordination teams. - Some emergency obstetric care projects still do not provide FP, even though free and qualitative FP should in principle be offered in all emergency obstetric projects. Prospects for 2013 - A guidance paper on collaboration with Traditional Birth Attendants (TBAs) will be developed. - The strengths and weaknesses of the MWH approach will be documented and an implementation paper on MWH paper - All missions offering TPR will be encouraged to conduct a context analysis and develop a modus operandi, hopefully with the full support of operations. - The SV database used in the Kenya, Egypt and DRC missions will be analysed in collaboration with the OR team. - The “SRH in emergency” toolkit will be finalised and disseminated to the field and operations. - The ALSO will be decentralised in the Pakistan and Afghanistan mission. - The ALSO training will be held twice (May and October 2013) in Denmark. - The International SRH course will be organised in September 2013. 24. sexual and reproductive health will be developed. MEDICAL ACTIVITY REPORT 2012 - Field visits will be conducted to the Kenya, Egypt, Afghanistan, Burundi and Somaliland missions. MSF MEdical Department OCB Surgical Activities 1. Overview While much progress has been made in the face of the burden of communicable and preventable diseases worldwide, the global burden of surgical diseases remains “neglected”, and continues to increase. The inequalities in surgical care are great: globally, more than 75% of health resources (human and material) for surgery are used by less than 25% of the population. In the environments where MSF works, these inequalities are larger still. During 2012, OCB provided essential, life-saving surgery, with low-tech requirements, based in district hospitals or primary health centres with surgical capacity. In parallel, following new operational strategies, OCB also provided high-standard orthopaedic care (e.g. osteosynthesis) in some projects. In addition, specialized surgical care was provided to women with obstetric fistula in various locations. Surgical activities were also supported as a functional part of non-emergency projects, and in some cases included a training component to build/strengthen the capacity of local staff. 80 2012 saw no major interventions following accidental trauma (such as was seen in Haiti in 2010) or violent trauma (e.g. the Ivory Coast in 2011). However, surgical activity was supported in conflict areas such as Syria, Mali, and Mauritania. OCB also provided indirect support in some cases by supplying material to perform surgical procedures. 2. Programme activities aspect of a surgical programme) and the were two projects doing orthopaedic sur- trends in direct surgical activities (i.e. support gery, which saw large volumes of patients 2.1. Surgical activities at project and mission level provided to surgical activities, but manage- with violent trauma. Five new surgical projects opened in 2012, 2.2. Surgical activities by indication sharp increase both in absolute numbers In all 22 OCB projects with surgical activities jects performing orthopaedic surgery. and seven projects were closed or handed over. Some projects continued to provide non-surgical care after the surgical component was ended. At the end of 2012, there were 15 OCB projects actively performing surgical activities. Surgical activities varied across projects, depending on context and need. For example, certain projects, such as Tabarre, Haiti and Timergara, Pakistan, were MEDICAL ACTIVITY REPORT 2012 25. surgical activities exclusively dedicated to emergency surgical care. In contrast, the Khost project (Afghanistan) is an MSF health structure exclusively ment the responsibility of another actor). during 2012 (seven closed over the course of the year and 15 active at the end of 2012), 15,813 primary interventions (new cases) were seen in 2012, representing a decrease of 18% from 2011 (19,296). This decrease in activities is linked in part to the handover and closure of several large projects (e.g. Lashkar-Gah in Helmand, Afghanistan, Lubutu in DRC, Dakoro in Niger and Dargai in dedicated to maternal/neonatal health, as is Pakistan). the Kabezi (Burundi) project (table 1, Annex). In terms of direct surgical activities (cf. §2.1., In contrast, the Gitega project (Burundi) is a 19 projects), 14,583 primary interventions highly specific OCB structure exclusively were performed in 2012, a decrease of 9% dedicated to obstetric fistula repair; this pro- from the previous year. When comparing the ject provides a good example of a strategy relative percentage of different indications for towards a neglected disease (obstetric fistu- surgery in 2012 with those in 2011, some la) where activities are performed all through significant changes can be observed (fig. 1): the year. - Violent trauma as a cause for intervention - Accidental trauma, in contrast, shows a (60%) and proportionally (9%). This increase can be directly linked to the pro- Obstetrical pathology remained the major cause for intervention in 2012, representing almost half of the new cases. This follows the trend of last year; however, there is a decrease in absolute numbers from 2011. In part for this reason, OCB surgical patients overall were predominantly women, and/or under the age of 30. - For other pathologies, there is a proportional decrease of cases of approximately 10%. Figure 1: Indications for surgery, expressed as percentage in relative weights, 2009-2012 100% Others 90% Obstetrical 80% Accident 70% Violence 60% 50% Similarly to the previous years (cf. Medical remained below 10% this year (8.8%). Activity Report 2011), in the analyses below However, an increase in absolute numbers 30% a distinction will be made for the overall of new cases from the prior year was ob- 20% trends in surgical activities (taking into ac- served. While 2012 was not marked by count all projects where OCB supports any emergency projects in conflict areas, there 40% 10% 0% 2012 2011 2010 2009 2.3. Performed anaesthesias During 2012, OCB provided anaesthesia for 100% 20,443 interventions (in all the 24 projects), 90% an 11% decrease from 2011 (22,964). The 80% total number of anaesthesias equals the total 70% number of entrances to the operating department (OD); it is higher than the number of proach uses functional operating theatres Figure 3: Surgical interventions, percentage in relative weights, 2009-2012 60% 50% 40% primary interventions because some proce- 30% dures were re-interventions. 20% and existing project staff, thereby allowing Minor/wound surgery Other gyn/obs & urology Orthopaedics/ specialized Visceral surgery Caesarean section 19,145 entrances to the OD were reported in 2012, similar to the previous year (19,644). The stable level of performed anaesthesias (entrances to the OD) in combination with the decrease in new cases (around 9%) can be explained by the increase of new cases with accidental trauma (around 10%) that often require re-interventions (fig. 2). pered in the project. Thus, both permanent and intermittent projects have proven effective in treating this neglected condition (cf. Sexual and Reproductive Health section, §2.7.). 2.7. Emergent surgery 10% For direct surgical activities (in 19 projects), normal surgical activities to continue unham- 0% 2012 2011 2010 2009 Emergent surgeries are urgent or delayed cases (with a wait of no more than a few days vious year (fig. 3). This is due to the fact that without significant morbidity). These are in the absolute quantity of interventions in 2012 contrast to planned elective surgery, which decreased, while there are still two hospitals can be delayed for a significant period of time devoted to orthopaedic care. Visceral sur- without an increase in morbidity. MSF per- gery was reduced to around 37% in absolute forms certain planned procedures that are numbers, and 7% as a proportion of total considered essential and address conditions surgeries. (amenable to a proven surgical treatment) that may not endanger the patient’s health immediately but cause the patient suffering, handicap, or disability. Comb/Others Caesarean section is a vital category of surgi- Local/Reg cal intervention, having a direct impact on In 2012, 16,996 emergent cases were re- Intubated maternal mortality. Due to their specificity, ported in direct surgical activities, represent- General most Caesarean sections are performed as a ing 89% of surgeries, slightly higher than in Spinal matter of urgency, and they are considered a 2011 (84%). This slight increase of emergent 40% first intervention every time with a new pa- cases can be linked to the performance of 30% tient. For 2012, the OCB projects with direct the specific surgical hospitals with orthopae- 10% activities performed 5,296 Caesarean sec- dic activities. Emergency Caesarean sec- 0% tions, a drop from the previous year, when tions (usually categorized as urgent) make up 6,255 surgeries were performed. The relative another large portion of this type of surgery, weight of this type of intervention was 36% as do trauma cases, which often present a as opposed to 39% in 2011 (fig. 3). substantial number of minor/wound cases 90% 80% 70% 60% 50% 20% 2012 2011 2010 2009 2.4. Surgical procedures by type 22,212 surgical procedures were reported in all 22 OCB projects in 2012. Direct surgical activities (in 19 projects) represented 20,865 interventions. These numbers are higher than the number of performed anaesthesias because in some cases more than one surgical procedure took place during an anaesthesia procedure/intervention. In the analysis below, however, only the 19,145 primary interventions of direct surgical activities will be included: not all projects systematically reported on multiple procedures per anaesthesia, and therefore only the primary intervention is taken into account to avoid any bias. In 2012, there was a decrease in Caesarean sections, not only proportionally (around 4%), but also in absolute numbers (around 15%). However, the quantity of performed Caesarean sections is still above the numbers of 2009 and 2010. In contrast, the proportion of orthopaedic/specialized surgery increased substantially in 2012, doubling from the pre- that can be delayed. 2.6. Obstetric fistula Obstetric fistula is a complication of delivery 2.8. Order of the intervention that occurs in resource-poor settings lacking A surgical intervention is either a first/primary, comprehensive emergency obstetrical care, a planned re-intervention, or an unplanned and particularly timely Caesarean section. re-intervention. This indicator is linked to the This condition affects the poorest levels of difference between the number of registered the society, where women are stigmatised new cases (first/primary intervention) and the and often excluded from the community due entrances to the OD. It also indirectly reveals to the smell and leakage arising from untreat- the type of patients managed (e.g. wounds ed obstetric fistula. During 2012, 408 pa- and burns often have multiple re-interven- tients with obstetrical fistula underwent surgi- tions). Unplanned re-interventions can be a cal repair, an increase from previous years. quality indicator because they represent Women who have been treated for obstetric post-operative complications of surgical pro- fistula are followed for six months post-sur- cedures that can be linked to professional gery to track their recovery. performance, availability of medical materi- The continuous, holistic project of Burundi (Gitega), focusing exclusively on obstetric fistula repair, was quite effective, treating 352 25. surgical activities 100% 81 2.5. Caesarean section als, availability of a post-operative recovery room, or quality of nursing follow-up of the patient in the hospitalisation ward. women in 2012. However, the vertical, sea- Of the direct surgical activities in 2012, 76% sonal integrated approach of DR Congo (Ma- were primary interventions, 23% planned re- sisi) project also continued with success, and interventions, and 1% unplanned re-interven- similar activities in Gogrial (South Sudan) tions. Compared with the previous years, commenced this year. The seasonal ap- there is a slight but significant increase of MEDICAL ACTIVITY REPORT 2012 Figure 2: Types of anaesthesia, percentage in relative weights, 2009-2012 planned re-interventions from the levels in 2011 (17.5%) to the levels previously observed in 2010 (23.4%). This can be explained by the performance of orthopaedic centres with their high volume of trauma-related patients, similar to the influx of traumarelated patients in post-earthquake Haiti in 2010, as these morbidities require several re-interventions during treatment. equal or higher than 3, it is considered as a risk factor for anaesthesia and for the development of post-operative surgical site infections. In general, more than 95% of the patients arrived at the OCB operating room with Course, surgical activities in OCB (twice). Emergency/Intensive Care) unit. Specialist - Future Surgical Approach, MSF Norway, doctors such as surgeons and anaesthesiol- on surgery within MSF – status quo and ogists are scarce and ones that can operate reflections for the future. in resource-limited settings are rarer still. The GAS (Gynaecology, Anaesthesia, Surgery) skills and knowledge and the expected skills - MSF UK Scientific Day: presentation of “A holistic approach to managing a neglected disease: the MSF experience on Obstetric Fistulae from Burundi.” and knowledge regarding the strategies and - Surgical Round Table, Singapore with MSF needs of the OCB Operations Department. Hong Kong, on MSF monitoring of surgical This year, GAS specialists training was pro- activities. vided for: - OCB Operational Research day, presenta- - Expatriate surgeons in obstetrical surgery, tion on: “Surgical activities in the 2011 Ivo- trauma and orthopaedic surgery, and ob- rian conflict: who are the patients and what stetric fistula. are their needs?” a ASA score of 1–2, meaning that less of 5% - National medical doctors performing sur- - MSF Hong Kong, V GAS week on drugs, of patients had a severe systemic disease or gery in orthopaedic, obstetric, and general materials and equipment; policies, guide- a severe incapacitating disease threatening surgery. lines, and protocols; surgical data collec- his/her life. 82 (twice in English and once in French). -Management of Health Services (MHS) specialists, taking into consideration their peri-operative morbidity and mortality. If it is agement and the importance of oxygen Reanimation, Gynaecology/ Obstetrics, and The American Society of Anaesthesiologists fitness. The ASA score is a good predictor of - Biomedical course on anaesthesia man- SAGE (Surgery/Orthopaedics, Anaesthesia/ training schemes target different types of into six subgroups by preoperative physical - National nurses in anaesthesia manage- Peri-operative mortality, defined as any death ment. In Haiti, participating nurse-anaes- occurring between the induction of the an- thetists received an MoH diploma after aesthesia and the patient discharge from the training. recovery room (the immediate recovery period), occurred in 0.2% of direct OCB surgical activities (33 deaths), a slight decrease in percentage over 2011 (0.3%). Not included are other post-operative periods, since time spent at the hospital varied between projects and surgical pathologies. Also, in the postoperative period, non-surgical causes of death were possible, making data interpretation difficult. The peri-operative mortality rate is strongly associated with the patient’s ASA score, emergency procedures, and the type of indication for surgery, as well as the available type of supportive care and resuscita- 25. surgical activities Training is an important core activity of the 2.9. Peri-operative mortality (ASA) score subjectively categorises patients MEDICAL ACTIVITY REPORT 2012 3. Human resources and training tion. Therefore, cross-sectional comparisons between projects can be misleading. However, this indicator is still useful for comparison within a project over time. - Community Health Officers in Sierra Leo- tion; war surgery, damage control surgery, and field anaesthesia. -Management of Health Services Course (French). MSF Burundi, on surgical activities in MSF-OCB ne, Bo, on obstetric emergent surgical - Trauma Seminar International Orthopaedic care, in joint venture with CAPA care (Nor- Association – Hong Kong, presentation of wegian NGO). This is a response to the “Doctors without Borders: Surgery under acute lack of surgical providers in the any Condition? Minimum requirements for country. Surgical Activity in Disasters”; “Quality Assurance for Disaster Relief. Surgery: MSF 4. Operational Research and presentations The SAGE unit published three peer-reviewed articles in scientific journals this year (cf. Operational Research & Documentation section, §5.: manuscripts and 73, 75 and 77). Presentations were conducted at the following events: - Surgical Master Course at MSF Italy and Verona University on principles of war surgery and ballistics, and field anaesthesia and pain management. Surgical Data Collection”; “Preparing humanitarian workers for disaster relief surgery: MSF Surgical Training Week.” - International School of Brussels, presentation of MSF and Surgery - International Society of Fistula Surgeons Congress. Dhaka, Bangladesh, presentation of “Obstetric Fistula in Burundi: a holistic approach to managing a neglected disease.” 5. Looking back and ahead Lessons learned for 2012 - Overall misunderstanding by several GAS specialists on the difference in level of surgical care between the developed world and MSF settings occurred. Some are too specialized and lack general surgery skills, while some also had an incomplete vision of the project. - A balance needs to be found between expectations of performing surgical activities and the required pre-conditions and field realities. - A high turnover of specialists and a high proportion of one-shot specialists risks compromising quality care. - Some GAS specialists lack managerial and teaching skills in supporting operational needs. - Supervision and evaluations of GAS specialists were absent in some projects. - The MSF documents regarding surgical activities are not widely known at mission/field level. - There were large fluctuations in the need for specialists, without maintenance of a critical volume in the field to keep efficiency in the human resource pools. - A clear impact was observed on the performance of GAS specialists by missing briefings in headquarters due the need for an “urgent” departure to the field. A day spent in briefings avoids long complications in activities in the field. Moreover, lack of briefings in headquarters of mission and field coordination posts had in some cases a detrimental result for surgical provisioning. - A gap in the expert opinion of the referents led to the purchase of non-standard or unneeded material in some projects. In most of such cases, the specialist requesting the material did not receive it, and the specialist that followed did not use it. Prospects for 2013 - GAS specialists will be trained in managerial and teaching skills, or more specialists with the correct background will be recruited. 83 - Support to the field will be continued. - The strength and support for trauma/orthopaedic surgical programmes will be increased. - The support for sexual and reproductive health activities by surgeons will be increased. - The present MSF surgical/anaesthesia related documents: policies, guidelines and protocols will be revised (intersectionally). - The guidelines on wound dressings and on circumcision will be finalised. - Guidelines for paediatric surgery and burn programmes in MSF settings will be developed. - Mass disaster response from the GAS specialist side will be strengthened. - The monitoring of surgical activities will be improved through quality indicators. - Build-up tools for “standard” surgical activities will be improved by defining different types of contexts. - The close collaboration with other organisations, in complementary (e.g. Handicap Int., SICOT for orthopaedic specialists) centres. MEDICAL ACTIVITY REPORT 2012 - Operational research will be conducted on the predictive values for haemorrhagic shock and head trauma in the specific OCB trauma 25. surgical activities and synergistic (e.g. FNUAP for obstetrical fistula, ICRC for war surgery) relationships, will be continued. MSF MEdical Department OCB Vaccination 1. Overview Throughout 2012, headquarters (HQ) support for vaccination activities in OCB missions was rather weak due to human resources constraints. On the other hand, efficient field support was provided by the Mobile Implementation Officer (MIO) in three missions. Evaluations of missed vaccination opportunities were done in six countries, providing a better understanding of the unmet vaccination needs. The total number of doses administered through routine vaccination activities in all projects decreased by 12% and post-exposure vaccination activities decreased by 13% compared to 2011. The number of cases of vaccine-preventable diseases detected routinely in several of our missions is alarming. Activities in Expanded Programmes of Immunisation (EPI) urgently need to be strengthened in these countries. 84 2. Programme activities Table 1: Distribution of programmes with routine vaccinations, 2012 (n=343,678) Among the 73 medical projects managed by Type of programme OCB in 2012, 27 (37%) reported vaccination OPD / ANC activities. IPD 2.1. Routine vaccination activities A total of 343,678 routine vaccinations Number of doses Proportion 288,836 84.0% 21,536 6.3% Nutrition 0 - HIV 0 - 33,306 9.7% Post-exposure ANC: antenatal care; IPD: inpatient department; OPD: outpatient department (310,372 as EPI and 33,306 as post-exposure) were administered in OCB projects over the course of the year 2012. This represents a reduction of 48,748 doses (12.4%) compared to 2011. This decrease is distributed equally between EPI and post-exposure vac- MEDICAL ACTIVITY REPORT 2012 26. vaccination cinations. 7,743 doses in 2011), which may reflect the victims of sexual violence, drop-out rates closure of the SGBV programme in Liberia. were 83% from the first to third dose of hepa- Vaccination of newborns in MSF programmes is either very weak or goes unreported. Available data show that only 22% of titis B and 88% for the two-dose tetanus vaccinations. Despite the revision of the vaccination policy in HIV programmes and lobbying to integrate The vast majority of routine vaccinations children born in OCB structures get vacci- (84%) were given through outpatient depart- nated with Polio 0 or BCG vaccines. The ad- ment (OPD) and antenatal care (ANC) con- ministration of anti-rhesus immunoglobulin sultations, while 6.3% were reported by inpa- post-delivery is not yet reported, although grammes in 2012. tient departments (IPD) (table 1). Of note, 1,280 doses of this product were supplied to The trend towards a decreasing proportion of data on routine vaccination performed in nu- the field in 2012. tetanus vaccination observed in 2011 was trition programmes is often incorporated into OPD data reporting, which gives a false impression of inactivity on the nutritional programme side. The quality of vaccination follow-up provided within OCB programmes is poor. Drop-out rates in the pentavalent vaccine (for diphtheria, pertussis, tetanus [or DPT], Haemophilus Overall, post-exposure vaccination repre- influenzae type B, and hepatitis B) from the sented 9.7% of OCB routine vaccinations. first to third dose among children were 38%, Almost 90% of post-exposure vaccines and while drop-out rates for tetanus vaccination derivatives were administered to wounded among pregnant women between the first patients, while the other 10% targeted vic- and the third dose was 78%. Unfortunately, tims of sexual and gender-based violence drop-out rates were even higher in post-ex- (SGBV). The number of vaccinations per- posure vaccination. They reached 59% in the formed by the SGBV projects in OCB de- series of four doses required for rabies vac- creased by almost half over the last year cination and 91% between the two doses of (3,456 doses administered in 2012 vs. tetanus vaccination of wounded patients. In this activity into the follow-up of the patients, no vaccinations were reported by HIV pro- continued in 2012. It now represents 31% of all routine vaccinations (compared to 40% in 2010) but remains the major antigen given routinely. The two other major vaccines (the first polio and the second DPT or pentavalent vaccination) continued to increase and represented respectively 26% and 19% of all routine vaccination performed by OCB in 2012. Over the last two years, measles vaccination given routinely decreased from 18% to 9% and pneumococcal vaccination (PCV) increased from 2% to 3% (fig. 1). Figure 1: Distribution of the antigens administered in routine vaccination in OCB programmes, 2012 (among 27 projects reporting vaccination activities; n=343,678) 3% 2% 9% Two preventive mass vaccination campaigns An outbreak of yellow fever also occurred in against measles were performed by the South Sudan, but all efforts made by the field emergency missions in Mali and Mauritania. teams to request permission to intervene A total of 1,102 children aged 6 to 59 months (case management and vaccination) were were vaccinated through the nutrition inter- unsuccessful. Tetanus vention in Mali (in Douentza and Mopti) and Polio the vaccination campaigns targeting the ref- DPT/Pentavalent ugee camp of Fassala in Mauritania reached 3. Developments and innovations BCG 16,472 children aged 6 month to 15 years Due to major human resource constraints all Measles old (cf. Emergency Unit section, §2.2.2.). year long, objectives and ambitions set for Preventive cholera mass vaccination in South 2012 had to be reduced. The comprehensive Sudan was prepared in 2012, but ultimately report on health promotion in vaccination only took place in January 2013. In 2012, and the technical tool for self-training on mul- 2.2. Evaluation of missed vaccination opportunities OCB responded to cholera outbreaks in ti-antigen coverage surveys could not be fi- DRC, Haiti, Guinea and Sierra Leone by nalized. None of the field missions introduced treating more than 15,200 cases. There was new vaccines, but several projects were nev- The results of six missed opportunity evalua- no reactive vaccination campaign launched ertheless developed: tions done during 2012 at the exit from health to respond to these outbreaks. - The use of solar refrigerators for routine PCV Others 19% 26% structures supported by MSF are presented in table 2. Other evaluations were done in Niger, Somaliland and Afghanistan but results are still pending. vaccination activities was continued in Ni- 2.4. Vaccine-preventable diseases angara (DRC). A system using cold packs rather than ice packs for passive cold This year saw a sizeable number of reported chains was set up in all covered health Results indicate that missed vaccination op- cases of diseases that are preventable by EPI structures. portunities varied between 15% and 48% in (table 3). The detection of such large num- children and between 14% and 30% in wom- bers in several countries such as Afghani- en of childbearing age. There seems to be an stan, DRC, and Niger is of major concern, improvement compared to last year’s results, and indicates an urgent need to reinforce although the low proportion of people who routine vaccination in all OCB projects run in would have agreed to be vaccinated if the these countries. -The frequently asked questions sheet (FAQ) on vaccine-preventable diseases was finalized. It is pending international 85 validation before distribution. vaccination had been proposed needs to be investigated further. Table 3: Distribution of cases of preventable diseases detected in OCB projects, 2012 2.3. Mass vaccination campaigns Suspected disease Cases Major countries affected Measles 2,305 Somalia (801), Afghanistan (679), DRC (305), South Sudan (163) Meningitis 678 Afghanistan (416), South Sudan (89), DRC (49), Haiti (24), Somalia (26), Pakistan (15) Tetanus 132 Afghanistan (108), Kenya (12), South Sudan (4), DRC, Somalia, Ethiopia, Haiti Neonatal Tetanus 61 Afghanistan (36), Pakistan (8), Niger (7), DRC (6), Sierra Leone, North Sudan nation campaigns (225,430 in DRC and Acute Flaccid Paralysis 185 DRC (158), Afghanistan (10), Ethiopia (9), Niger, India, South Sudan, Sierra Leone 132,249 in South Sudan). Two smaller epi- Diphtheria 53 Kenya (30), Afghanistan (17), DRC (6) Pertussis 783 Niger (608), South Sudan (81), Afghanistan (53), Ethiopia (23), DRC, Sierra Leone Risk of rabies 828 Afghanistan (441), DRC (167), India (105), Kenya (51), Ethiopia (50) In 2012, OCB responded to major measles outbreaks in DRC and South Sudan. A total of 7,168 cases were treated during these two outbreaks and more than 357,679 persons were vaccinated through mass vacci- demics were detected and responded to in Burundi and Ethiopia, where respectively 20,000 and 662 individuals were vaccinated. DRC: Democratic Republic of Congo Table 2: Evaluations of missed vaccination opportunities, 2012 Place Structure Date Target Sierra Leone (Bo) General Hospital Jan 2012 0-59 months 134 n Missed opportunity* 48% 97% South Sudan (Gogrial) PHCC Sep 2012 0-12 months 203 15% 74% DRC (Niangara) OPD Nov 2012 0-59 months 118 19% 45% DRC (Niangara) IPD Nov 2012 0-59 months 77 21% 50% DRC (Niangara) OPD Nov 2012 W 15-45 y 159 14% 57% DRC (Niangara) Maternity Nov 2012 W 15-45 y 33 30% 60% * Missed Opportunity = proportion of target population exiting a health structure that has missed an opportunity of being vaccinated during their visit. ** Agreed = proportion of individuals with missed vaccination opportunities that would have agreed to be vaccinated if vaccination had been proposed. IPD: inpatient department; OPD: outpatient department; PHCC: primary health care centre Agreed** 26. vaccination 11% MEDICAL ACTIVITY REPORT 2012 30% - The OCB protocol and toolkit for studying missed vaccination opportunities was finalized and used for all evaluations performed in 2012. 4. Training - OCB gave support to one training on Responding to Epidemics (REPEPI, in French) and to the vaccination module of the Management of Health Services (MHS) course. - Three decentralized trainings on EPI were organized in Niger (Guidan Roumdji), India (Mon and Chhattisgarh), and DRC (Niangara). 5. Looking back and ahead Lessons learned for 2012 - In 2012, the MSF International Vaccination Working group completed a four-year analysis of vaccination activities at the international level, concluding that not enough resources had been provided to reach the goal of increasing routine vaccination activities in MSF. Last year, OCB projects implementing vaccination lacked efficient support from HQ, which could explain the reduction in the number of routine vaccinations performed in OCB missions. - Fortunately, 2012 was a very quiet epidemic year. The extension of the preventive vaccination campaigns with the Meningitis A conjugate vaccine (MenAfriVac) in countries along the meningitis belt probably played a major role in the reduction of the occurrence of meningitis outbreaks over the last years. OCB should support this initiative in countries where it has activities. - Implementation of EPI in the field requires good collaboration and strong interest from the team. It cannot start before all the necessary material is available in the field. The presence of an expatriate is needed to set up the system, train the staff and supervise the start of the activities. Another visit needs to be planned after six months to evaluate the system, provide direct support, and correct mistakes. 86 - Specific reports suggested that vaccination coverage improved in SGBV projects, was still weak in nutrition programmes, and remained completely absent in HIV projects. The concerned International Working Groups (IWG) should work on mutually satisfying data collection tools. - Documentation of missed vaccination opportunities increased in 2012 and provided a more comprehensive picture of the problem. Prospects for 2013 - The routine vaccination activities will be increased in nutrition and HIV programmes, following the new protocols that have been agreed on internationally (antigens and schedule). - Routine vaccination activities will be emphasised in programmes developed in South Sudan, Sierra Leone, Niger and DRC. Specific focus will be put on DRC, where OCB will coordinate international efforts to introduce new vaccines and boost vaccination in all programmes. - Emergency preparedness will be reinforced in countries at risk and investigations and response to outbreaks will be strengthened. - The MSF response to meningitis and measles outbreaks is to be refined according to current understanding of epidemiology and context. - The use of new vaccines (PCV, cholera) in reactive or preventive mass vaccination campaigns needs to be explored. MEDICAL ACTIVITY REPORT 2012 26. vaccination - The missed vaccination opportunities will continue to be documented in order to better tackle the unmet needs. Qualitative studies are envisaged to better understand reticence to vaccination wherever identified. - Reporting of vaccination activities and follow-up of vaccination indicators in all projects needs to be strengthened. MSF MEdical Department OCB Water, Hygiene and Sanitation 1. Overview The 2012 activities of the Water, Hygiene and Sanitation (WHS) unit were dominated by interventions in the refugee camps in South Sudan and Mauritania. Emergency responses to viral haemorrhagic fevers (VHF) in DRC and Uganda, hepatitis E in South Sudan and cholera responses in Sierra Leone and Guinea, and to some extent in Haiti were also important in scale. Additionally, installation of WHS infrastructures in state-of-the-art MSF hospitals was high on the operational agenda in 2012. The intersectional WHS working group continued to serve as an expedient platform for development and dissemination of tools and guidelines and for harmonising intersectional WHS activities. Operational collaborations, such as interactions on the WHS approach during the refugee crisis in South Sudan or VHF outbreaks in Uganda and DRC, were successfully managed by the working group, and a large number of tools for further standardisation of WHS activities were developed. All outputs of this intersectional collaboration were shared through Tukul. Similarly to 2012, OCB did not manage any vertical WHS projects due to its transversal or integrated nature, while almost all OCB projects included a WHS component. Systematic scanning for WHS needs was performed for all OCB projects – trained Water and Sanitation (WatSan) personnel from the pool were then sent to the field if the WHS needs proved too complex or large for the - A new issue that needed attention was scaling of sterilisation equipment and destruction of the heating element by high water calcium levels in the MSF-supported hospital in Libya. - Chemical water quality is a challenge faced in an increasing number of contexts due to agricultural and industrial pollution – in 2012 an emergency investigation was initiated in Zimbabwe. - Provision of water by boreholes was complicated in Bo hospital in Sierra Leone, as state-of-the-art hospitals are important consumers of water as well as producers of waste water that needs to be treated before discharge into the environment. This was also the case in the new Kibera clinic in Kenya and during the installation of WatSan infrastructures in Imey hospital in Ethiopia. - In Somaliland a WatSan visit was initiated in 2012 to improve the degraded WatSan situation in a prison where in particular the field staff. In 2012, a focus was placed on -Regarding water quality, state-of-the-art providing expert WHS support to established borehole rehabilitation techniques were in- missions, while the WHS needs in the large troduced in Niger to avoid repeated drilling OCB emergency interventions were mainly of new boreholes, and drilling machines al- - The typhoid fever situation in Harare was addressed by polyvalent staff with technical lowing ground water exploration up to 100 studied in collaboration with Epicentre and support from headquarters. About 45 WHS metres deep were implemented for refu- revealed post factum the importance of experts supported projects in 10 missions gees in inhospitable areas in South Sudan. two contaminated wells in the transmis- (Afghanistan, Guinea, Haiti, Niger, DRC, Si- Satellite imaging was used to detect water sion. Bucket chlorination was implement- erra Leone, Mauritania, South Sudan, Zim- sources in South Sudan when all surface ed as an emergency intervention. An im- babwe and Malawi). water was consumed by refugees and de- proved technical solution was studied and tection of groundwater became an impor- will be implemented in 2013 in prepared- tant challenge during the dry season. ness for potential future outbreaks. sanitation component will need an innovative approach. 27. Water, hygiene and Sanitation 2.1. Activities at project and mission level 2.2. Specific WHS interventions and field visits MEDICAL ACTIVITY REPORT 2012 2. Programme activities 87 In addition to the strong support of the WHS unit to both regular and emergency OCB projects, a large number of operational research and innovative initiatives were launched over the course of the year. These included support to the Operations Department to identify a context for a project on prevention of infant diarrhoea, which was approved by the MSF Innovation Fund; refining the intervention strategy for hepatitis E in South Sudan, for cholera in Haiti and Guinea and for typhoid fever in DRC and Zimbabwe; testing of the chemical water quality in health structures; contribution to an intersectional effort in Haiti to compare several methodologies of waste water treatment in medical infrastructures; development of new borehole rehabilitation techniques in a nutritional project in Niger; and trialling novel water identification and drilling techniques in South Sudan. -Installation of water and sanitation infra- - Preparation and organisation of a common of the new Dengue kit and listing the structures in Mauritanian refugee camps expert to compare and validate waste wa- missed opportunities where use of this kit was an important challenge given the par- ter treatment equipment in Haiti. would have been helpful. ticular security situation on the ground and the delays faced by other humanitarian actors to become operational. - New approaches were being developed to combat cholera in Guinea and Malawi. - VHF outbreaks in Uganda and DRC required WHS expertise to set up the treatment centres, limit the transmission of the disease in the population and train and collaborate closely with the national Minis-In the Kabezi project of Burundi, mud streams provoked by heavy rain and erosion flooded the hospital. In collaboration with the Musée Royal d’Afrique Centrale Research Unit (LuxOR) enabled the WHS The WHS unit, in close collaboration with the tions in peer reviewed journals in 2012 (cf. intersectional working group, was involved in the generation of a broad array of documents and guidelines (disseminated during 2012), including: ous Situations”, published in 2012 as MSF Public International MSF guideline. - An update of the international WHS library list. -Technical and editorial support to two repetition of this event was studied with World Health Organisation (WHO) publica- the help of satellite imagery. tions: 1) Malaria control in complex emer- The intersectional working group on Water, Hygiene and Sanitation has been active since 2007 to improve the intersectional coherence for WHS issues. Over the course of 88 4.1. Documents, guidelines (MRAC) of Tervuren, Belgium, the risk of 3. International coherence 2012, activities of the WHS working group included: gencies – an interagency field handbook 2) Menstrual Hygiene Manual. The close collaboration with the Operational working group to generate several publicaOperational Research & Documentation section, §5., publications 55, 61 and 81). Additionally, a considerable number of operational research initiatives were launched over the course of 2012: - A cross-sectional, random-sample survey to assess water chlorination as an intervention against cholera and to identify risk factors for cholera transmission in Cité Soleil, Haiti, during the cholera epidemic (manuscript submitted to the Ethics Committee in Haiti). - A study comparing the Rotating Biological Contactor as packaged sewage and sul- - A number of MSF manuals, such as 1) a lage plant (managed by OCB), the upflow draft version of the waste water manual, 2) sand filter clarifier (managed by OCA), a the construction and operation manual for single septic tank (managed by OCP) and the intermediate metal burner, 3) an up- multiple septic tanks in line (managed by date of the medical waste-related manuals OCG) in health structures in Haiti (study (demontfort, safety box reducer, emergen- planned in spring 2013). - Three meetings of the working group, with cy facilities, waste zone operator manual). -A study into the feasibility, acceptability minutes and presentations disseminated - A contribution to the evaluation of the Ma- and impact of postnatal health facility dis- ban South Sudan intervention (to be pub- tribution of water filters on diarrhoeal mor- lished in 2013). bidity and mortality in infants (study ac- through Tukul. - Exchange of experience and improved coherence on technical approaches in the context of VHF, disseminated through an intersectional “lessons learned” document. - A conference call was organised to discuss the common action plan of 2013. 27. Water, hygiene and Sanitation 4.3. Operational research - The “Public Health Engineering in Precari- try of Health (MoH) staff. - Organisation of a technical day in Amsterdam on cholera guidelines. - A contribution to the evaluation of the container hospital of Tabarre in Haiti. - A contribution to the GPS-GIS strategic positioning document in collaboration with OCG 4.2. Tools (including The WHS unit, in close collaboration with the shared human resources under the form of intersectional working group, was involved in WHS pools) in emergencies, especially in the generation of a series of tools: VHF outbreaks in Uganda and DRC. - Scaling of sterilisation equipment: follow- - Intersectional collaboration - Development of common operational approaches, such as an update of the recommendations on long-lasting insecticidetreated nets (LN) to streamline purchasing MEDICAL ACTIVITY REPORT 2012 4. Developments and innovations for central or field emergency stocks, and field visits by experts for incinerators used in Haiti. -Systematic updates of the WHS group space on Tukul, including technical documents, digital maps, presentations and meeting minutes. up on impact of water softeners on scaling process + other alternatives. - Chlorination: verification of a pool tester measuring residual chlorine. - Water testing: testing the compact dry EC test as an alternative to bacteriological water testing with Delagua kit. - Cholera bed: a new cholera bed was developed in collaboration with a new supplier. - Dengue: capitalisation on the practical use cepted by the MSF Innovation Fund and awaiting identification of an appropriate operational context). - A cross-sectional study to verify chemical water quality in MSF-supported medical infrastructures, in collaboration with SGS (study protocol under development by the end of 2012). - Assessing the effect of refugee camp location on the capacity to meet humanitarian standards in the 2011/12 South Sudan refugee crisis. - Pre-emptive protocol to be submitted to the ethical committee, aiming to improve the evidence base for WHS interventions in cholera control. - A study on how the detection of early epidemic risk factors, combined with a timely malaria vector control intervention, can prevent the evolution and impact of malaria epidemics, using Wajir district, Kenya, as a case study. gation to determine water and sanitationrelated risk factors in high transmission global humanitarian aid event organised in Brussels - Participation in the Roll Back Malaria meeting in Geneva. -Presentation on “The development of -Participation in the “Humanitarian medi- onsite wastewater treatment in Cholera cine and extractive industries” workshop Treatment Centers”, “Desludging with organized by the MSF reflection unit in Ge- - Performing a typhoid fever outbreak inves- tractor and vacuum trailer in Haiti”, “Biode- neva. tigation to determine water and sanitation- gradable bags as emergency sanitation in related risk factors and high transmission urban settings: the MSF field experience” zones during the 2012 outbreak in Harare, during the interagency sanitation work- Zimbabwe shop in Delft. zones during the 2011 outbreak in Kikwit, DRC. (cf. Epidemiology/Epicentre section, §2.1.). -Participation as observer in the WASH cluster meeting at the Water, Engineering and Development Centre of Loughborough University, UK. - Presentation of “The Haitian population fac- - External training (e.g. Institute of Tropical 4.4. Communication ing cholera for the first time: awareness ef- Medicine, Bioforce, University of Johan- forts and applied anthropology”, “Using MSF experience in WHS activities was ac- nesbourg, Liverpool School of Tropical modern mapping techniques to identify pri- tively shared at multiple platforms through Medicine). ority areas for WASH intervention during a scientific presentations and discussions, in- typhoid outbreak in Harare, Zimbabwe”, cluding: “The development of onsite wastewater - Presentation on “WHS activities for cholera treatment in Cholera Treatment Centers” prevention in communities living adjacent and “Does village water supply affect chil- to Lake Kivu or Rusizi river, Cyangugu dren’s length of stay in a therapeutic feeding Province, Rwanda” on the 6th World Water program in Niger? Lessons from a Mé- Forum in Marseille. decins Sans Frontières program” on the - Presentation on “Does village water supply affect children’s length of stay in a therapeutic feeding program in Niger? Lessons Emergency Environmental Health Forum in the London School for Hygiene and Tropical Medicine. 5. Training & human resources The WHS unit was involved in over 50 fulltime days of dedicated trainings – including the WHS module of the Populations in Precarious Situations (PSP) training, the WHS in Emergencies training (English and French), the Response to Epidemics (REPEPI) course and the Water, Engineering and Development Centre course – as well as providing WHS components for trainings such as the from a Médecins Sans Frontières program” -Presentation of “Mudstream predictive Preparation for Primary Departure (PPD) on the OCB Operational Research Day in model in Kabezi, Burundi” in collaboration course, Management of Health Structures Brussels (cf. Operational Research & Doc- with the MRAC Tervuren. (MHS) course, Basic Logistics Course umentation section, §2.3.). - Presentation of “WASH in a Medical Hu- -Presentation on “Reflective analysis on manitarion Organisation” to the IUPWARE practice of humanitarian health – Ebola a group of the Universities of Brussels and case study” in the “Ecole des hautes Leuven. études en Santé Publique” in Paris - Presentation of innovative WHS tools developed by MSF on Aidex international, the - WHS input during a one week MSF module in medical masters training on Tropical (BLoC), and others. Additionally, in an inter- 89 - Designing a typhoid fever outbreak investi- sectional collaboration, new modules were developed on GPS mapping with Google Earth, practical aspects of VHF isolation practices, pipe installations and Emergency Preparedness (Eprep). Surgery in Verona University, Italy. Lessons learned for 2012 The intersectional working group continues to demonstrate its worth and has managed to harmonise the WHS activities of the different sections. The dedicated working group space on Tukul is a well-suited communication channel for the working group, but information flow could benefit from further attention. An increasing number of operational research studies focusing on WHS has been launched. This serves to improve the international visibility of OCB WHS activities and will increasingly allow OCB to shape the WHS agenda of other actors in the field. 27. Water, hygiene and Sanitation 6. Looking back and ahead Prospects for 2013 The high level of technical support to the field on all WHS issues will be maintained, and the systematic scanning of WHS needs in projects, feeding into the Annual Review of Operations process, will continue. Particular attention will be devoted to the improved information flow between headquarters and the field, improved knowledge and skills both at headquarters and field level through intersectional WHS trainings, and further roll-out of innovative tools. Additionally, the unit will attempt to influence the WHS agenda MEDICAL ACTIVITY REPORT 2012 A close collaboration with the Operational Research Unit has been forged in the process, to the mutual benefit of both units. and strategies of other actors in the field through increased sharing of the MSF experience through different communication channels (including conferences, peer-reviewed literature, etc.). Perspectives concerning the intersectional working group work include interacting on cross-cutting issues with other working groups (such as nutrition, HIV, tuberculosis, malaria, VHF, etc.), further positioning of the working group in a number of strategies, a comparison of the WHS training trajectories to harmonise the process. Furthermore, a common WHS policy paper, endorsed by the medical and logistical directors platforms, will be developed and its implementation monitored. The “Public Health Engineering in Precarious Situations” has been published in 2012 as MSF Public International MSF guideline and will be translated into French in 2013. In terms of training perspective, a collaboration with the “Office Internationale d’Eau” will be sought, in order to be able MEDICAL ACTIVITY REPORT 2012 27. Water, hygiene and Sanitation 90 to offer trainings for WatSan experts who already did the WHS in Emergencies course and are in need of expert skills. MSF - Operational Centre Brussels - MEdical Department OCB MEDICAL ACTIVITY Annex of tables and data MSF-OCB - Belgium - Brazil - Denmark - Hong Kong - Italy - Luxembourg Norway - South Africa - Sweden MSF MEdical Department OCB annex of tables and data 2012 Contents 92 Contents pages section 05: medical Data Table 1: OCB global summary of outpatient and inpatient data using Epicentre OPD/IPD/Gynobs Tools in 2012 93 section 07: Emergency Medicine Table 1: OCB emergency department activities in 2012 (as reported by 13 projects) 94 section 10: Evaluation unit Table 1: Findings and recommendations from evaluations carried out during the course of 2012 95 section 12: Health Promotion and Socio-Anthropology Table 2: OCB emergency interventions with HP activities, 2012 Table 3: OCB projects with HP/anthropological activities, 2012 98 99 section 16: Laboratory Table 1: OCB laboratory activities, 2012 101 section 19: Mental Health Table 1: MH activities integrated into OCB medical projects, 2012 Table 2: OCB MH activities in emergency/short term interventions, 2012 102 103 section 20: Nutrition Table 4: OCB therapeutic feeding programmes in 2012 by project Table 5: OCB supplementary feeding programmes in 2012 by project Table 6: OCB targeted food or nutritional support in 2012 by project 104 105 105 section 21: Operational Research & Documentation 105 section 25: Surgical Activities Table 1: Overview of OCB surgical activities per project, 2012 108 8,498 NA 13.8 1,383 13,986 3.7 4,727 17,380 NA NA NA NA NA NA 50.4 1,590 NA NA NA NA NA NA NA NA NA NA Burundi DRC 2,103 25.1 5,007 14,809 3.8 1.0 95.2 8,994 4,284 9,044 68,095 176,936 186,163 353 0.0 290 4,758 3.8 6.7 89.4 624 233 631 7,087 27,256 27,922 Ethiopia NA NA 1,937 NA 1.5 1.9 96.6 4,001 1,060 4,117 7,756 51,387 64,548 Haiti annex of tables and data 2012 section 05: medical Data 4,160 8.8 673 4,328 2.7 15.1 82.2 1,833 207 1,890 8,684 50,782 53,080 India ANC: antenatal care; DRC: Democratic Republic of Congo; IPD: inpatient department; NA: not available; N°: number N° of Family Planning consultations Caesarean sections N° of deliveries N° of ANC consultations 6.4 13.5 Defaulters % Deaths % 80.2 20,096 8,392 Discharged % N° of IPD exits <5 yrs 41,781 77,742 20,857 N° of <5 yrs N° of IPD admissions NA 42,537 261,590 New cases 46,674 Bangladesh 263,534 N° of Consult Afghanistan Table 1: OCB global summary of outpatient and inpatient data using Epicentre OPD/IPD/Gynobs Tools in 2012 Kenya 93 18,007 NA NA 12,090 NA NA NA NA NA NA 32,655 87,314 116,016 Mali 40 1.0 96 436 3.0 1.0 96.0 99 58 111 1,524 4,772 4,862 Niger 3,928 0.0 1,640 26,534 5.2 0.4 94.4 12,575 12,407 12,574 196,945 197,274 240,385 3 18.1 94 5,062 2.3 0.2 97.6 573 205 647 9,254 34,203 35,635 North Sudan 8 44.7 1,461 NA 8.0 2.7 89.3 7,267 7,601 8,754 47,901 56,554 56,554 Sierra Leone NA 9.3 658 NA 4.1 0.0 95.9 197 171 230 NA NA NA Somaliland Total 37,100 12.4 28,815 90,124 5.9 6.1 77.0 56,258 34,618 58,855 499,424 990,605 1,095,373 MSF MEdical Department OCB section 05: Medical Data section 07: Emergency Medicine Jan-Dec 34,286 0.2 22.7 Jan-Dec 9,881 0.6 99.9 0.1 7.8 21.4 20.5 6.3 823 Jan-Sep 36,854 ND 22.9 ND 0 26 ND 32.6 4,095 Lashkar-Gah Afghanistan Kunduz Jan-Mar 1,379 0 13.8 ND ND ND ND ND 460 Lubutu DRC Jan-Dec 4,921 ND 22.3 ND ND ND ND 40.3 410 Masisi Jan-Dec 4,591 ND 6 ND ND ND ND 47 383 Niangara Haiti Jul-Dec 21,752 0.1 66.9 0 4.5 ND 42.1 14.7 3,625 Martissant 94 Feb-Dec 2,873 0.1 92.8 0.6 2.4 61 29.6 5.1 279 Tabarre DRC: Democratic Republic of Congo; ED: emergency department; GRC: Gondama Referral Centre; ND: no data available Months of data Total number of cases Mortality rate Percentage of Trauma cases ND ND Admission rate Defaulter rate ND Female percentage 2 3 0.5 Percentage of patients < 5 years Referral rate 2,857 Kabul Mean cases per month Project ED Table 1: OCB emergency department activities in 2012 (as reported by 13 projects) annex of tables and data 2012 Oct-Dec 1,220 0.3 16.6 2.8 5.4 0 46.8 26.5 505 Jan-Dec 76,310 1.2 18.8 ND 2 ND ND ND 6,272 Timurgara Pakistan Karachi Jun-Dec 4,963 0.7 1.8 0.2 1.1 92.5 45.8 86.1 709 GRC - Bo Sierra Leone Jan-Dec 7,212 1.4 28.8 2 1 23.3 41.2 18.2 627 Burao Somalia Jan-Dec 3,655 0.6 9.9 ND 2.1 34.1 ND 36 305 Jan-Dec 1,760 0.3 12.8 ND 0.1 13.7 ND 47.2 147 Pibor South Sudan Gogrial India Jan-Dec 7,489 ND ND ND ND ND ND ND 624 Nagaland MSF MEdical Department OCB section 07: Emergency Medicine MSF MEdical Department OCB section 10: Evaluation unit Table 1: Findings and recommendations from evaluations carried out during the course of 2012 Project Main Findings Main recommendations Mozambique, Maputo: Evaluation of stakeholder perceptions. Report presented to the Cell and available on Tukul. - The MSF presence is seen as very relevant: pioneering HIV treatment and representing a reliable partner. Handover - MSF implementation strategies are appropriate and ‘day to day’ presence is seen positively. - Gap filling and substitution are perceived as unsustainable; some stakeholders believe MSF has unintentionally contributed to insufficient programme ownership among the MoH health centre staff. - Developing and implementing innovative models of care is seen as very appropriate and a particular strength of MSF. - Infrastructure support (donations of laboratory equipment, drugs, reagents and supplies) is much appreciated but some stakeholders feel there are shortcomings in system strengthening. - Partners feel that MSF is integrated well in the national health care system but with some limitations. - Overall communication and coordination is perceived as very good but there is room for further improvement. - Most stakeholders feel that MSF advocates appropriately. - Some stakeholders state that financial implications of MSF proposed changes should be given more consideration. - Most stakeholders feel that the handover of first line support is premature although the health leadership finds the handover timely and is fully supporting it. - The difficulties absorbing the human resources are perceived as the biggest challenges. - A good handover communication strategy was highlighted by several stakeholders as being of importance. - The handover steering committee is perceived as an excellent participatory approach. - Capitalise on the opportunities of the handover steering committee and foster ownership through participatory planning and monitoring. - Identify realistic solutions to cover the upcoming human resources gap e.g. provincial common fund, other funds, continued MSF sub-agreement or identifying a local NGO for the psychosocial care component. - Use the strength and capacity of MSF for innovation to design and implement an accelerated targeted capacity-building strategy that focuses on health centre management and all the relevant critical departments, including, pharmacy, laboratory, reception, data collection, monitoring and evaluation, clinical, PMTCT and psychosocial support. - Together with partners, assess the need for institutional support to the City Health Directorate i.e. provincial supervision capacity for HIV care and treatment, and consider on-going support after handover. - Continue to further develop the urban community ARV groups as a user-friendly patient empowering strategy that can help keep retention in care at an acceptable level in the Mozambican context of overburdened and understaffed health facilities. - Develop a handover communication strategy for the different target groups, spelling out clearly which areas MSF is going to hand over and which areas MSF will continue to support. 95 - The impact of MSF work is substantial; MSF stands for quality HIV care, good service organisation and good treatment outcomes. Future role of MSF - For the development of the future MSF programme support, capitalise on the positive handover steering committee experience and use participatory planning methods, involving all relevant stakeholders, and design the new programme and coordination mechanisms in a way that will foster true partnership and partners’ ownership right from the beginning. annex of tables and data 2012 section 10: evaluation unit - Stakeholders feel that MSF has still an important role to play in HIV programmes in Mozambique. Project Main Findings Main recommendations Sanou MSF: Evaluation of the training programme. Report presented across departments and available on Tukul. Appropriateness For headquarters - The target group for Sanou MSF is defined as all MSF staff, whether national or international. - Develop a broader range of Sanou materials from which coordinators can select the most appropriate. - The objectives defined for the training do correspond to the identified needs. - Update the Sanou training materials regularly. Pertinence and appropriateness - The methodology of Sanou MSF is appropriate although it could be more culturally appropriate and contextually relevant. - Material is not translated and widely accessible to MSF staff e.g. speakers of local languages, etc. - Adaptations and translations risk distorting the international nature of MSF. - Develop a standard ‘participant evaluation form’ and reporting format. - Centralize all reporting and feedback for analysis and follow-up. Effectiveness - Continue to use the existing coordinators while also developing new ones. - Senior staff said Sanou has made a noticeable difference to staff motivation and improved HR management. - International staff participation is very important to the success of Sanou. - Proper participant evaluation has not always been undertaken and followed. - Reports from facilitators have not been consistent and little analysis has been done. - Proper coordination of Sanou is time consuming but is a critical factor for its success. Efficiency 96 - Develop an accreditation system for Sanou facilitators. - Develop a central (OCB) implementation plan for Sanou. - The benefits of Sanou are not restricted to new staff, national staff or junior staff. - Sanou was developed as a cost effective solution which capitalises on mission capacities. - The role of the Coordination Teams in organising has not always been clear. - Not always clear which department is responsible for leading Sanou. - Some larger missions have recruited someone just to coordinate Sanou. - Ensure that Sanou is fully integrated into other HR and training initiatives including the on-going development of the PPD. - Explore further options for maximizing the use of Sanou intersectionally. For the field - Ensure that Sanou trainings delivered in local languages (and those that are simplified and shortened) have adequate international staff input to reflect the international nature of MSF and to ensure that discussions on different cultures can be effective. - Ensure that proper attendance records are kept locally in missions and are available centrally (HQ) to monitor the progress of Sanou roll-out. - Ensure every Sanou MSF participant completes the standard evaluation form. - Ensure a short report in a standard format is prepared by the Sanou coordinator and kept in the mission giving feedback points on how the training went. - Develop a mission-based Sanou roll-out plan that includes intended coverage, timescale, resources required and responsibility for overseeing and monitoring. These plans for implementing Sanou should be reflected in the Annual Review of Objectives process. - Some missions have developed shorter Sanou trainings. - Make adequate resources available in missions for coordinating Sanou either through an HR Development Officer or a mission Sanou coordinator. - Translating and simplifying the materials has made Sanou more accessible in some missions. Sanou and beyond Impact - Sanou has been very positive with over 90% of respondents reporting a positive impact on their motivation. section 10: evaluation unit - Promote international staff participation in Sanou. - - Sanou MSF has been effective in fulfilling its overall objective. annex of tables and data 2012 - Provide a Sanou lead in HQ to support and coordinate centrally. - Sanou reportedly has positive impacts on many other operational areas. Continuity and connectedness - Sanou MSF is connected to current OCB and intersection HR initiatives - For all projects and initiatives, document the identified needs and defined objectives as well as a plan for how these needs will be met. This helps implementation and follow-up on results. Project Main Findings Main recommendations Pakistan: Review of operational choices and decisions 2005-2010. Report presented to the cell and available on Tukul. History Improving strategic clarity - The OCB Pakistan mission has experienced three distinct phases: - Define the broader ‘strategic’ objectives of the mission, including using operations in Khyber Pakhtunkhwa to help facilitate access to other areas with high levels of need by building local networks and trust, and incorporate these into the key documents for the mission and projects. - Phase 2: Response to numerous displacements; challenges relate to external factors inherent in a conflict environment; - Phase 3: Expanding (scope of) operations; increasing public profile and medical activities. Acceptance - General suspicion or mistrust towards NGOs based on belief (cultural, religious, economic and political). Generalized and not directed specifically at MSF. - Improving acceptance is achieved primarily through provision of ‘quality’ and free services. - Acceptance of MSF is localized and conditional (on the provision of services). - Security has been a major challenge for the Pakistan mission and improving acceptance of MSF is one key to improving its security. - Factors that limit MSF reaching those most in need include poor security, the need for international staff and the decision not to accept armed guards. - Factors affecting beneficiaries’ services include: transport (availability and cost), lack of awareness and cultural restriction. - People (groups) excluded from services likely include the rural poor and women (who face additional cultural barriers). - The communications strategy was the primary tool for overcoming the challenges relating to negative perceptions of NGOs. - The visibility strategy (dynamic process rather than a written document) has also had a significant positive impact. - The networking strategy (documented) ensured a broad network and constant contact with stakeholders but fails to engage third level groups or the general population. - The MSF intersectional agreement (documented) was identified by few although many talked about elements of it. - Cultural sensitivity (including dress and other forms of behavior) was recognized by all and had a positive impact. - Ensure that briefings to all staff, and particularly expats, give equal weight to both the strategic rationale and the medical rationale for programme intervention in order to manage expectations and limit frustrations. - Ensure project documents are clear about the strategic objective and clearly define what activities will be carried out in order to achieve it. In particular they need to be clear how the MSF presence will help gain access to other areas of high levels of need and how the extent to which this has been successful will be measured. - Ensure clearer and more consistent justification of operational choices and decision making in key documents and briefings so it is clear why MSF has decided to work in its current locations, given that there are high levels of health needs everywhere in the region. Locate the current choices within the broader context and strategic objectives of the mission. Improving communications - MSF has not effectively communicated its identity to the general population. In order to improve acceptance, it is important that MSF establishes contacts at community level. Therefore, extend the communications and networking strategies to include the general population or groups who might be representative of them (for example teachers, taxi drivers etc.). - Provide additional external support for teams in order to directly engage with the population. - Ensure that this engagement with the population does not support or overly focus on dominant local groups or individuals but also includes those who are often excluded. 97 - Phase 1: Set up of early operations; specific challenges and constraints relate to location and type of activities; - Ensure that teams continue to gather information about the needs and perceptions of the population, so that any changes or new needs can be responded to and services remain appropriate. - There is limited awareness of MSF amongst patients. Re-orientate the communications strategy to place the patients at the centre and make them the primary ambassadors for MSF’s services. - Final report pending - Final report pending DRC: Evaluation of the PUC project - Postponed until 2013 - Postponed until 2013 Haiti: Capitalisation on lessons learned from Martissant - Postponed until 2013 - Postponed until 2013 ARV: antiretrovirals; DRC: Democratic Republic of Congo; HQ: headquarters; HR: human resources; MoH: Ministry of Health; NGO: non-governmental organisation; PMTCT: Prevention of Mother-To-Child Transmission of HIV; PPD: preparation for primary departure course; PUC: Pool d’Urgences Congo annex of tables and data 2012 South Sudan: Evaluation of the Maban Refugee Emergency section 10: evaluation unit - The human resources strategy (refers to various initiatives to improve HR development) has been successful in retaining highly motivated staff. MSF MEdical Department OCB section 12: Health Promotion and Socio-Anthropology Table 2: OCB emergency interventions with HP activities, 2012 Country Emergency in 2012 Type of HP activities Mauritania Conflict - Promotion of MSF services - Health education on primary health care (in camps and for the local population) South Sudan Doro - Health Surveillance (mortality, nutrition, etc.) - Promotion of MSF services - Health education (in the health facilities and in the camp) on all relevant medical topics (maternal health, nutrition, etc.) - Prevention of faeco-oral diseases (Hepatitis E, etc ). Sierra Leone Cholera - - - - annex of tables and data 2012 section 12: Health Promotion and socio-Anthropology 98 HP: health promotion; KAP: Knowledge, Attitude and Practice Promotion of MSF services Health education on cholera Prevention activities on transmission of cholera KAP survey on hygiene practices Project Key activities in 2012 Lashkar-Gah (Helmand) - Participation in the study on antibiotic resistance (cf. Laboratory section, §4.) - Revision of all HP activities and messages - Specific focus on hygiene Kabul - Starting up HP activities - Health education on all relevant topics (maternal health, nutrition, etc.) Kunduz - Starting up HP activities - Specific focus on blood donation and personal hygiene Bangladesh Kamrangirchar - HP activities in the PHC clinics: ANC/PNC, waiting area, etc. - HP activities in the community: active screening for malnutrition, social case assessments, promotion of the services for women’s health - Survey on barriers to accessing SRH services for adolescent and young women Burundi Kabezi - Health education on SRH: family planning, kangaroo methods, ANC/PNC, STI - PMTCT: opt out strategy for all women Gitega - Promoting services in the community - Screening strategy in the different provinces - Inside the health centre of Urumuri: health education on fistula, hygiene, nutrition, malaria, etc.; physiotherapy activities; recreation activities Niangara - Awareness campaign and mobilisation for routine EPI activities - Evaluation of the sexual violence component strategy - Ongoing health education activities in the hospital Masisi - Satisfaction survey on the medical care provided to the HIV patients in Masisi Hospital - Rationalization of the network of “mamans conseillères” for victims of sexual violence - Ongoing health education activities in the hospital and in the community HAT - In Kikongo: mobilisation for screening population and HP activities on vector control strategies - In Kasai oriental: exploratory mission to collect info on socio-cultural context, perception of HAT, health seeking behaviour; awareness campaign and mapping of the area Kinshasa PUC - Cholera intervention in Mbandaka - Ebola intervention in collaboration with OCBA Kinshasa Coordination - Satisfaction survey for MSF staff and their beneficiaries regarding their medical care Nasr City Cairo - Ongoing collection of info on migrant profiles and their migration path - Coaching of the HP supervisor - Ongoing HP activities Abu Elian - Defining the HP strategy - Hiring an HP team and training for treatment of children under five - KAP survey on health seeking behaviour for women and children under five Imey - - - - Haiti Choscal, Sarthe, Martissant - HP activities in the different projects: Choscal, Sarthe and Martissant India Chhattisgarh - HP activities supporting all the medical activities in the different health facilities and in the catchment areas: PHC, malaria, nutrition, tuberculosis, maternal health, etc. - Supporting the context analysis of the area affected by conflict Nagaland - HP activities in OPD, IPD & communities on all medical issues tackled in the hospital: SRH, hygiene, malaria, blood donations, etc. - Specific focus on tuberculosis patients Italy Migrant’s health - Promotion of services in collaboration with the MoH and a local NGO - HP activities on tuberculosis in closed centres for migrants - HP activities on Chagas for Latin American migrants in theBergamo area Niger Dakoro - Ongoing HP activities - Preparing disengagement phase and reduction of activities Guidan Roumdji - HP activities in the community: nutrition and tuberculosis defaulters tracing; community meetings; individual interviews of patients lost to follow up - HP activities in ATFC: health talks, appetite tests, individual interviews, reference briefings, referral briefings - HP activities in ITFC: specific support on routine vaccination, health talks, television spots, recreation activities, cooking demonstrations, counselling Dargai - Supporting the disengagement phase and the closing process of the project Timergara - In the hospital, HP activities moved from purely supporting health care waste management to all relevant medical topics: hygiene, maternal health, diabetes, etc. - Specific support on measles - Design of a new strategy to start HP activities in the community through the Lady Health Workers Karachi - Hiring and training of an HP team - Opening of the project in October 2012. HP activities launched in the clinic since the beginning: PHC, maternal health care, information on MSF - HP activities in the community: promotion of the services targeting specific communities Bo (outreach) - Ongoing HP activities in five outreach areas Egypt Ethiopia Pakistan Sierra Leone Promoting MSF services in East and West Imey communities HP activities for the patients and caretakers in East and West Imey health centres HP activities in the community through mobile clinics (four outreach locations) Closing of the project: designing the HP exit strategy section 12: Health Promotion and socio-Anthropology DRC annex of tables and data 2012 Afghanistan 99 Table 3: OCB projects with HP/anthropological activities, 2012 Somaliland Burao - HP activities on hygiene and maternal health in the hospital - Mobilization for fistula campaign - Meetings with key people from the community (to be organized in the hospital) South Soudan Gogrial - In the PHC centre: refreshment of HP topics, prioritization of HP messages and adaptation/creation of related tools for each department; exit interviews on drug use; daily games activity in ITFC - Supporting the measles vaccination campaign - Mobilization for fistula campaign - In the community: defaulter tracing for tuberculosis and nutrition, meetings with key people, referral system, surveillance system Pibor - Changing the setup of the HP team: HP team fully integrated in other departments - HP activities supporting all relevant medical topics: SRH, malaria, EPI, hygiene, nutrition, tuberculosis, blood transfusion - Specific activity on SRH: 18 month campaign: from pregnancy to PNC - HP activities in the community: defaulter tracing, meetings with key people, etc. South Africa Johannesburg - Cleaning campaign in several urban slum buildings - Zimbabwe Harare (sexual violence) - Develop adapted tools for promotion of services - Awareness raising on sexual violence: partnership with other actors and with the MoH; networking; training of volunteers from partner organization; participation to key events (specific celebration days); and health talks in the clinic annex of tables and data 2012 section 12: Health Promotion and socio-Anthropology 100 ANC: antenatal care; ATFC: ambulatory therapeutic feeding centre; DRC: Democratic Republic of Congo; EPI: extended programmes of immunisation; HAT: human African trypanosomiasis; HIV: Human Immunodeficiency Virus; HP: health promotion; IPD: inpatient department; ITFC: inpatient therapeutic feeding centre; MoH: Ministry of Health; NGO: non-governmental organisation; OCBA: MSF Operational Centre Barcelona; OPD: outpatient department; PHC: primary health care; PMTCT: prevention of mother-to-child transmission; PNC: postnatal care; PUC: pool d’urgences Congo; SRH: sexual and reproductive health; STI: sexually transmitted diseases; TB: tuberculosis MSF MEdical Department OCB section 16: Laboratory Table 1: OCB laboratory activities, 2012 No. of Labs HIV & TB Kinshasa 1 1 TB Transfusions (only) Hospital (transfusions included) Other Project status Ongoing Lubutu Closed Masisi 1 Niangara 1 Bandoudu/Kasai 1 Burundi Bujumbura 1 1 Somalia Galgaduud 1 1 Somaliland Burao 1 Kenya Nairobi 1 1 Ongoing Guinea Conakry 1 1 Ongoing Gueckedou 1 1 Port-Sudan 1 Pibor 1 Gogrial 1 Niger Dakoro 1 Guidan Roumdji 1 Haiti Port-au-Prince 2 India Nagaland 1 Ukraine Donetsk 1 Ethiopia Imey Zimbabwe 1 (HAT) Expected closure Ongoing Ongoing 1 Ongoing 1 Expected closure 1 1 Ongoing Ongoing 1 Ongoing 1 1 Expected closure 1 Ongoing 1 Ongoing 1 Ongoing 1 (MDR-TB) Ongoing Closed Dire Dawa 1 Birch. B. 1 Gutu 1 New 1 Ongoing 1 New 1 Ongoing Murambinda 1 Khayelitsha 1 1 Musina 1 1 Expected closure KwaZulu-Natal 1 1 New Thyolo 1 1 Ongoing Nsanje 1 1 New Sierra Leone Bo 1 LESOTHO Roma 1 Mozambique Maputo Tete South Africa Malawi 1 (MDR-TB) Ongoing 1 Ongoing 1 New 1 1 Ongoing 1 1 Ongoing Angonia Afghanistan Total Active Laboratories 101 South Sudan Ongoing Ongoing section 16: Laboratory North Sudan 1 1 Closed Kabul 1 Khost 1 Lashkar-Gah (Helmand) 1 Kunduz 1 33 35 1 Ongoing 1 New 1 Expected closure 1 15 3 9 Ongoing 9 2 __ ANC: Antenatal Care; DRC: Democratic Republic of Congo; HAT: Human African Trypanosomiasis; MDR-TB: multidrug resistant tuberculosis; TB: tuberculosis annex of tables and data 2012 DRC Project MSF MEdical Department OCB section 19: Mental Health Table 1: MH activities integrated into OCB medical projects, 2012 Country Project Type of activities No. individual consultations1 No. group sessions New MH activities Pakistan Karachi MH support integrated within the OPD in an urban slum. 199 (Mid Oct-Dec) 33 (444 persons) Afghanistan Lashkar-Gah (Helmand) MH support integrated within the medical OPD services (MH activities will be handed over to OCA early 2013). 285 (Nov-Nov) NA Egypt Cairo SV activities for migrants from the different communities. 205 (May-Dec) NA South Sudan Doro MH support to the refugees from Blue Nile state (group and individual) with a specific attention to the beneficiaries of nutritional activities (since September). 401 1,547 (946 therapeutic or discussion groups 53,093 persons) Haiti Tabarre MH support to patients referred by medical teams in the hospital (since May) 247 NA 102 Ongoing MH activities Egypt Cairo Psychological and psychiatric support for migrants from the different communities. 1115 NA Afghanistan Kabul MH support integrated within medical services of Ahmad Shah Baba district hospital, Kabul. NA NA Pakistan Timergara Psychological support integrated in the MSF medical services (postoperative care, emergency room and mother and child health). 1,545 76 (1,109 persons) Kenya Kibera SV centre, Olympic, in the outskirts of the Kibera slum. 1,082 NA Kibera MH support integrated within the PHC and HIV/TB consultations. Sierra Leone Bo, Gondama Referral Centre MH support integrated within the referral centre (GRC, secondary level) for nutrition, TB, HIV and SV. 491 6 South Africa Musina, migrants from Zimbabwe Care for SV victims. 133 cases (no of psy consultations ND) NA DRC Masisi Psychological support to SV victims. 887 10 (71 persons) Haut Uélé, Niangara Psychological support to victims of the conflict, including SV victims 1,338 51 (605 persons) Zimbabwe Murambinda, HIV project Psychological support to victims of sexual, domestic or political violence provided by counsellors to the patients of the HIV cohort. ND ND Zimbabwe Harare Care for SV victims. 904 patients NA India Mumbai Psychological and psychiatric support for MDR-TB/3 line HIV patients. 3,004 369 Ukraine Donetsk Psychological and psychiatric support of MDR-TB/HIV patients in prison. 824 (April-Dec) 61 (1027 persons) (April-Dec) Bahrain Manama Psychological support for the victims of violence; trainings in MH. ND NA Libya Misrata, Sirte Individual consultations in two prisons. Individual and group sessions for victims of conflict in the community. Training of national psychologists in MoH hospitals and schools. 76 (Jan-March) 157 (3,893 persons) (JanMarch) Tripoli Psychological support and SV activities to migrants and IDPs. Individual consultations and group support for medical teams in hospitals. 162 (Jan-March) 35 (Jan-March) Somalia Galgaduud Psychopharmacologic treatment of MH disorders by medical staff in Guri El Hospital. ND NA Liberia Monrovia SV project integrated within 2 MoH structures: New Kru Town clinic and JDJ clinic. 644 patients (Jan-June) NA Haïti Port-au-Prince, Martissant Individual consultations and group support in IPD, OPD, and SV care. 1,486 NA ND ND rd annex of tables and data 2012 section 19: Mental Health Project closures Bo, outreach project Sierra Leone 1 MH support integrated within 5 PHC clinics for nutrition, TB, HIV and abortion. Not including HIV counselling sessions ER: Emergency Room; IDP: Internally Displaced Persons; IPD: Inpatient Department; MH: mental health; MoH: Ministry of Health; NA: not applicable; ND: no data available; OPD: Outpatient Department; PHC: Primary Health Care; SRH: Sexual and Reproductive Health; SV: Sexual Violence; TB: Tuberculosis/MDR-TB: multidrug resistance tuberculosis Table 2: OCB MH activities in emergency/short term interventions, 2012 1 Country Project Type of activities No. individual consultations 1 No. group sessions South Sudan Batil MH support to the refugees from Blue Nile state (group and individual) with a specific attention to the beneficiaries of nutritional activities. (Oct-Dec) 40 142 (1,216 persons) Jamam MH support to the refugees from Blue Nile state (group and individual) with a specific attention to the beneficiaries of nutritional activities. ND ND Doro Cf. new project. Pibor Post immediate psychological support of the community (including national staff)-training in Psychological First Aid after acute episode of violence. (Feb-March) 77 ND Syria Beirut Regular training for Syrian MH professionals (counsellors and psychiatrists). NA NA Bahrain Dubai Training of Bahraini professionals linked to victims of violence. NA NA Not including HIV counselling sessions. annex of tables and data 2012 section 19: Mental Health 103 MH: mental health; NA: not applicable; ND: no data available MSF MEdical Department OCB section 20: Nutrition Table 4: OCB therapeutic feeding programmes in 2012 by project Country Project locations No. patients % hospitalized % cured* % died* % defaulted Vertical programmes/Emergencies DRC Goma (refugees)1 25 25 75 0 0 Mauritania Mbera Malian refugees 3,877 1.4 39 1 51 Assaba 1,653 5.7 70.5 0.4 24.8 Mali Mopti, Douentza 1,418 26.2 65 3.3 26.4 South Sudan Maban refugees (Doro, Batil) 5,454 8.4 67.9 0.9 24.52 888 71.1 65.9 4.6 29.5 Integrated programmes Afghanistan Lashkar-Gah, Kabul Bangladesh Kamrangirchar (Dhaka) 1,126 NA 50.9 0 41.2 DRC Niangara, Lubutu 319 41.4 69.8 7.1 19.3 Ethiopia Imey 653 19.6 ND ND ND India Chhattisgarh (Ayam Pradesh) Niger Dakoro, Guidan Roumdji 185 NA 8.4 0.6 89.7 29,814 18.7 82.6 2.7 6.9 3 14.2 2.5 Sierra Leone GRC (Bo) 1,059 100 Somalia Guri-El (Galgaduud) 636 46.1 ND ND ND North Sudan4 Darfur: Shaeria 549 5.6 85.5 1.7 11.1 South Sudan Pibor, Gogrial5 7,293 5.3 68.2 1.6 30.2 ND ND ND ND ND 405 3.4 57.9 2.9 11.0 83.7 104 HIV programmes * DRC Kinshasa Kenya Nairobi/Kibera 6 Data based on beneficiaries of 6-59 months of age for vertical and integrated programmes and beneficiaries of all age groups for HIV programmes. DRC: Democratic Republic of Congo; NA: not applicable; ND: no data received 1DRC Goma: 3 weeks activity. Hospitalised indicates transferred, as no ITFC was present. No data available on outcomes of transfer. 2The defaulter rate was especially high in January and from June to August. Long lengths of stay were also noted, which improved when protection rations were introduced. In the other months, the defaulter rate was between 4 & 12%. 3Only ICU and < 6 months. < 6 months represent 26% of admissions. “Cured” includes cured and transferred to MoH ITFC and ATFC. 4As the project has been temporarily suspended by national security and medical computers containing data were not updated, some weeks are missing. 5In South Sudan, outcomes were calculated on the first semester (data was not available for the second semester). annex of tables and data 2012 section 20: nutrition 6Kibera: hospitalised indicates transferred, as no ITFC was present. Table 5: OCB supplementary feeding programmes in 2012 by project Country Project No. patients % cured* % died* % defaulted* Kibera/HIV clinics 298 69.1 2.3 15.8 HIV programmes Kenya * Data based on beneficiaries of 6-59 months for vertical and integrated programmes and beneficiaries of all age groups for HIV programmes. NA: not applicable; ND: no data received Table 6: OCB targeted food or nutritional support in 2012 by project Country Project No. patients Type of programme India HIV/TB Mumbai 25 Nutrition during illness Guinea HIV Conakry & Gueckedou 143 Nutrition during illness Kenya HIV Kibera 444 SFC FBF South Sudan Pibor 3,831 Nutrition support for PLW FBF: Fortified Blended Flour; ND: no data; PLW: Pregnant and Lactating Women; SFC: Supplementary Feeding Centres; TB: tuberculosis MSF MEdical Department OCB section 21: Operational Research & Documentation 105 List of OCB-associated publications, 2012 1.Viewpoint: Zachariah R, Harries AD, Srinath S, Ram S, Viney K, Singogo E, et al. Language in tuberculosis services: can we change to patientcentred terminology and stop the paradigm of blaming the patients? Int J Tuberc Lung Dis. 2012 Jun;16(6):714-7. 2. State of the art: Bianchi L, Dahmane A. La recherche opérationnelle ou «la science des meilleures pratiques» Le modèle de Médecins Sans Frontières. EHL-Info. 2012;20:43-4. 3.Viewpoint: Zachariah R, Ford N, Maher D, Bissell K, Van den Bergh R, van den Boogaard W, et al. Is operational research delivering the goods? The journey to success in low-income countries. Lancet Infect Dis. 2012 May;12(5):415-21. 4.Viewpoint: Harries AD, Zachariah R. Applying DOTS principles for operational research capacity building. Public Health Action. 2012;2(4):101-2. 5.Viewpoint: Harries AD. Operational research: getting it done and making a difference. Public Health Action. 2012;2(1):1-2. 6.Viewpoint: Zachariah R, Draguez B. Operational research in non-governmental organisations: necessity or luxury? Public Health Action. 2012;2(2):31. 7.Viewpoint: Zachariah R, Reid T, Ford N, Van den Bergh R, Dahmane A, Khogali M, et al. The 2012 world health report ‘no health without research’: the endpoint needs to go beyond publication outputs. Trop Med Int Health. 2012 Aug 16. 8.Viewpoint: Zachariah R, van Griensven J. Crossing the divide: expanding the scope of operational research in Public Health Action. Public Health Action. 2012;2(4):98. 9. Original research: Bissell K, Harries AD, Reid AJ, Edginton M, Hinderaker SG, Satyanarayana S, et al. Operational research training: the course and beyond. Public Health Action. 2012;2(3):92-7. 2. Viewpoint – comment on (10): Ditiu L, Kumar B. Tuberculosis care: why the words we use matter. Int J Tuberc Lung Dis. 2012 Jun;16(6):711. 3. Viewpoint – comment on (10): Baral S, Newell J. Language in tuberculosis services. Int J Tuberc Lung Dis. 2012 Aug;16(8):1129; author reply -30. 4. Viewpoint – comment on (10): Biot M, Saranchuk P, Ellman T, Bygrave H, Bemelmans M. Change to patient-centred terminology in tuberculosis: an important step, but what about the treatment strategies? Int J Tuberc Lung Dis. 2012 Nov;16(11):1559-60. 5. Original research: Decroo T, Van Damme W, Kegels G, Remartinez D, Rasschaert F. Are Expert Patients an Untapped Resource for ART Provision in Sub-Saharan Africa? AIDS Res Treat. 2012;2012:749718. 3. Health Programme Monitoring & Management 6. Original research: Kondapaka KK, Prasad SV, Satyanarayana S, Kandi S, Zachariah R, Harries AD, et al. Are tuberculosis patients in a tertiary care hospital in Hyderabad, India being managed according to national guidelines? PLoS One. 2012;7(1):e30281. (Union-MSF course student) 7. Original research: Lumala R, van den Akker T, Metcalf CA, Diggle E, Zamadenga B, Mbewa K, et al. CD4 testing at clinics to assess eligibility for Antiretroviral therapy. Malawi Medical Journal. 2012;24(2):25-8. 8. Original research: Delai MY, Gounder S, TaylerSmith K, Van den Bergh R, Harries AD. Relationship between education and training activities and tuberculosis case detection in Fiji, 2008–2011. Public Health Action. 2012;2(4):142-4. (UnionMSF course student) 9. Original research: Lal PG, Wilson NC, Gupta PC. Attributable deaths from smoking in the last 100 years in India. Current Science. 2012;103(9):108590. (Union-MSF course student) 10.Original research: Cornell M, Schomaker M, Garone DB, Giddy J, Hoffmann CJ, Lessells R, et al. Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study. PLoS Med. 2012 Sep;9(9):e1001304. 11.Original research: Ram S, Kishore K, Batio I, Bissell K, Zachariah R, Satyanarayana S, et al. Pretreatment loss to follow-up among smear-positive pulmonary tuberculosis cases: a 10-year audit of national data from Fiji. Public Health Action. 2012;2(4):138-41. (Union-MSF course student) 12.Original research: Afutu FK, Zachariah R, Hinderaker SG, Ntoah-Boadi H, Obeng EA, Bonsu FA, et al. High initial default in patients with smear-positive pulmonary tuberculosis at a regional hospital in Accra, Ghana. Trans R Soc Trop Med Hyg. 2012 Aug;106(8):511-3. (Union-MSF course student) 13.Original research: Errol L, Isaakidis P, Zachariah R, Ali M, Pilankar G, Maurya S, et al. Tracing patients on antiretroviral treatment lost-to-followup in an urban slum in India. J Adv Nurs. 2012 Nov;68(11):2399-409. 14.Original research: Rasschaert F, Koole O, Zachariah R, Lynen L, Manzi M, Van Damme W. Short and long term retention in antiretroviral care in health facilities in rural Malawi and Zimbabwe. BMC Health Serv Res. 2012 Dec 5;12(1):444. section 21: Operational Research & Documentation 2. Health Systems & Health Policy 1. State of the art: Edginton M, Enarson D, Zachariah R, Reid T, Satyanarayana S, Bissell K, et al. Why ethics is indispensable for good-quality operational research. Public Health Action. 2012;2(1):21-2. annex of tables and data 2012 1. Operational Research 15.Original research: Namuwenge PM, Mukonzo JK, Kiwanuka N, Wanyenze R, Byaruhanga R, Bissell K, et al. Loss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda. Trans R Soc Trop Med Hyg. 2012 Feb;106(2):84-9. (Union-MSF course student) HIV 16.State of the art: Bygrave H, Saranchuk P, Makakole L, Ford N. Feasibility and benefits of scaling up antiretroviral treatment provision with the 2010 WHO antiretroviral therapy guidelines in rural Lesotho. International Health. 2012;4:170-5. 17.State of the art: Lynch S, Ford N, van Cutsem G, Bygrave H, Janssens B, Decroo T, et al. Public health. Getting HIV treatment to the most people. Science. 2012 Jul 20;337(6092):298-300. 18.Review: Andrieux-Meyer I, Calmy A, Cahn P, Clayden P, Raguin G, Katlama C, et al. Preferred antiretroviral drugs for the next decade of scale up. J Int AIDS Soc. 2012;15(2):17986. 19.Review: Harries AD, Zachariah R. AIDS Review. Africa Health. 2012:42-3. 20.Review: Sabapathy K, Van den Bergh R, Fidler S, Hayes R, Ford N. Uptake of Home-Based Voluntary HIV Testing in Sub-Saharan Africa: A Systematic Review and Meta-Analysis. PLoS Med. 2012 Dec;9(12):e1001351. 21.Viewpoint: Roberts T, Bygrave H, Fajardo E, Ford N. Challenges and opportunities for the implementation of virological testing in resource-limited settings. J Int AIDS Soc. 2012;15(2):17324. annex of tables and data 2012 section 21: Operational Research & Documentation 106 22.Guidelines: Meintjes G, Maartens G, Boulle A, Conradie F, Goemaere E, Hefer E, et al. Guidelines for antiretroviral therapy in adults. Southern African Journal of HIV Medicine. 2012;13(3):114-33. 23.Original research: Davies MA, Boulle A, Technau K, Eley B, Moultrie H, Rabie H, et al. The role of targeted viral load testing in diagnosing virological failure in children on antiretroviral therapy with immunological failure. Trop Med Int Health. 2012 Sep 14. 24.Original research: van Lettow M, Akesson A, Martiniuk AL, Ramsay A, Chan AK, Anderson ST, et al. Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi. PLoS One. 2012;7(11):e48856. 25.Original research: Wandeler G, Keiser O, Mulenga L, Hoffmann CJ, Wood R, Chaweza T, et al. Tenofovir in second-line ART in Zambia and South Africa: collaborative analysis of cohort studies. J Acquir Immune Defic Syndr. 2012 Sep 1;61(1):418. 26.Original research: Estill J, Aubriere C, Egger M, Johnson L, Wood R, Garone D, et al. Viral load monitoring of antiretroviral therapy, cohort viral load and HIV transmission in Southern Africa: a mathematical modelling analysis. Aids. 2012 Jul 17;26(11):1403-13. HIV/Tuberculosis Co-infection 27.Review: Harries AD, Lawn SD, Getahun H, Zachariah R, Havlir DV. HIV and tuberculosis--science and implementation to turn the tide and reduce deaths. J Int AIDS Soc. 2012;15(2):17396. 28.Viewpoint: Kumar AMV, Gupta D, Gupta RS, Satyanarayana S, Wilson N, Zachariah R, et al. HIV testing in people with presumptive tuberculosis: time for implementation. Lancet Resp Dis. 2012;Early online. 29.Viewpoint: Saranchuk P, Bedelu M, Heiden D. Retinal Examination Can Help Identify Disseminated Tuberculosis in Patients With HIV/AIDS. Clin Infect Dis. 2013 Jan;56(2):310-2. 30.Original research: Isaakidis P, Varghese B, Mansoor H, Cox HS, Ladomirska J, Saranchuk P, et al. Adverse events among HIV/MDR-TB co-infected patients receiving antiretroviral and second line anti-TB treatment in Mumbai, India. PLoS One. 2012;7(7):e40781. 44.Original research: Jonnalagada S, Harries AD, Zachariah R, Satyanarayana S, Tetali S, Keshav Chander G, et al. The timing of death in patients with tuberculosis who die during anti-tuberculosis treatment in Andhra Pradesh, South India. BMC Public Health. 2011;11:921. (Union-MSF course student) 31.Original research: Kerschberger B, Hilderbrand K, Boulle AM, Coetzee D, Goemaere E, De Azevedo V, et al. The effect of complete integration of HIV and TB services on time to initiation of antiretroviral therapy: a before-after study. PLoS One. 2012;7(10):e46988. Malaria 32.Original research: Kanyerere HS, Mpunga J, Tweya H, Edginton M, Harries AD, Hinderaker SG, et al. Timing of antiretroviral therapy and effects on tuberculosis treatment outcomes in HIV-coinfected patients in Malawi. Public Health Action. 2012;2(4):174-7. (Union-MSF course student) 45.Original research: Bawo LL, Harries AD, Reid T, Massaquoi M, Jallah-Macauley R, Jones JJ, et al. Coverage and use of insecticide-treated bed nets in households with children aged under fi ve years in Liberia. Public Health Action. 2012;2(4):112-6. (Union-MSF course student) 33.Original research: Rangaka MX, Wilkinson RJ, Glynn JR, Boulle A, van Cutsem G, Goliath R, et al. Effect of antiretroviral therapy on the diagnostic accuracy of symptom screening for intensified tuberculosis case finding in a South African HIV clinic. Clin Infect Dis. 2012 Dec;55(12):1698-706. 34.Original research: Bedell RA, Anderson ST, van Lettow M, Akesson A, Corbett EL, Kumwenda M, et al. High prevalence of tuberculosis and serious bloodstream infections in ambulatory individuals presenting for antiretroviral therapy in Malawi. PLoS One. 2012;7(6):e39347. 35.Original research: Fenner L, Reid SE, Fox MP, Garone D, Wellington M, Prozesky H, et al. Tuberculosis and the risk of opportunistic infections and cancers in HIV-infected patients starting ART in Southern Africa. Trop Med Int Health. 2012 Nov 30. Tuberculosis (including drug-resistant tuberculosis) 36.Review: Ahuja SD, Ashkin D, Avendano M, Banerjee R, Bauer M, Bayona JN, et al. Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. PLoS Med. 2012;9(8):e1001300. 37.Review: Cox H, Ford N. Linezolid for the treatment of complicated drug-resistant tuberculosis: a systematic review and meta-analysis. Int J Tuberc Lung Dis. 2012 Apr;16(4):447-54. 38.Viewpoint: Cox H, Ford N, Hughes J, Goemaere E. Linezolid for multidrug-resistant tuberculosis. Lancet Infect Dis. 2013 Jan;13(1):16. 39.Original research: Cox H, Escombe R, McDermid C, Mtshemla Y, Spelman T, Azevedo V, et al. Wind-driven roof turbines: a novel way to improve ventilation for TB infection control in health facilities. PLoS One. 2012;7(1):e29589. 40.Original research: Coulborn RM, Panunzi I, Spijker S, Brant WE, Duran LT, Kosack CS, et al. Feasibility of using teleradiology to improve tuberculosis screening and case management in a district hospital in Malawi. Bull World Health Organ. 2012 Sep 1;90(9):705-11. 41.Original research: Nagaraja SB, Kumar AM, Sachdeva KS, Ramachandran R, Satyanarayana S, Bansal A, et al. Is one sputum specimen as good as two during follow-up cultures for monitoring multi drug resistant tuberculosis patients in India? PLoS One. 2012;7(9):e45554. (Union-MSF course student) 42.Original research: Malhotra S, Zodpey SP, Chandra S, Vashist RP, Satyanaryana S, Zachariah R, et al. Should sputum smear examination be carried out at the end of the intensive phase and end of treatment in sputum smear negative pulmonary TB patients? PLoS One. 2012;7(11):e49238. (UnionMSF course student) 43.Original research: Kundu D, A MVK, Satyanarayana S, Dewan PK, Achuthan Nair S, Khaparde K, et al. Can follow-up examination of tuberculosis patients be simplified? A study in chhattisgarh, India. PLoS One. 2012;7(12):e51038. (Union-MSF course student) Nutrition 46.Original research: Dorion C, Hunter PR, Van den Bergh R, Roure C, Delchevalerie P, Reid T, et al. Does Village Water Supply Affect Children’s Length of Stay in a Therapeutic Feeding Program in Niger? Lessons from a Medecins Sans Frontieres Program. PLoS One. 2012;7(12):e50982. 47.Original research: Shams Z, Zachariah R, Enarson DA, Satyanarayana S, Van den Bergh R, Ali E, et al. Severe malnutrition in children presenting to health facilities in an urban slum in Bangladesh. Public Health Action. 2012;2(4):107-11. (UnionMSF course student) 48.Original research: Ali E, Zachariah R, Hinderaker SG, Satyanarayana S, Kizito W, Alders P, et al. Does the 65 cm height cut-off as age proxy exclude children eligible for nutritional assessment in Bangladesh? Public Health Action. 2012;2(4):1036. (Union-MSF course student) Other Infectious Diseases 49.Viewpoint: Hasker E, Lutumba P, Chappuis F, Kande V, Potet J, De Weggheleire A, et al. Human african trypanosomiasis in the democratic republic of the congo: a looming emergency? PLoS Negl Trop Dis. 2012 Dec;6(12):e1950. 50.Original research: Isaakidis P, Mansoor H, Zachariah R, Da Silva EA, Varghese B, Deshpande A, et al. Treatment outcomes in a cohort of patients with chronic hepatitis B and human immunodeficiency virus co-infection in Mumbai, India. International Health. 2012;4:239-45. 51.Original research: Khonje A, Metcalf CA, Diggle E, Mlozowa D, Jere C, Akesson A, et al. Cholera outbreak in districts around Lake Chilwa, Malawi: Lessons learned. Malawi Medical Journal. 2012;24(2):33-7. 52.Original research: Luque Fernandez MA, Schomaker M, Mason PR, Fesselet JF, Baudot Y, Boulle A, et al. Elevation and cholera: an epidemiological spatial analysis of the cholera epidemic in Harare, Zimbabwe, 2008-2009. BMC Public Health. 2012;12:442. Non-Communicable Diseases 53.Viewpoint – comment on (64-67): Maher D. The power of health information - the use of cohort monitoring in managing patients with chronic non-communicable diseases. Trop Med Int Health. 2012 Oct 11. 54.Viewpoint – comment on (64-65): Mullins J. Cohort reporting improves hypertension care for refugees. Lancet. 2012 Aug 11;380(9841):552. 55.Original research: Khader A, Farajallah L, Shahin Y, Hababeh M, Abu-Zayed I, Kochi A, et al. Cohort monitoring of persons with hypertension: an illustrated example from a primary healthcare clinic for Palestine refugees in Jordan. Trop Med Int Health. 2012 Sep;17(9):1163-70. 56.Original research: Khader A, Farajallah L, Shahin Y, Hababeh M, Abu-Zayed I, Kochi A, et al. Cohort monitoring of persons with diabetes mellitus in a primary healthcare clinic for Palestine refugees in Jordan. Trop Med Int Health. 2012 Oct 11. 57.Original research: Lin Y, Li L, Mi F, Du J, Dong Y, Li Z, et al. Screening patients with Diabetes Mellitus for Tuberculosis in China. Trop Med Int Health. 2012 Jul 25. 58.Original research: Li L, Lin Y, Mi F, Tan S, Liang B, Guo C, et al. Screening of patients with tuberculosis for diabetes mellitus in China. Trop Med Int Health. 2012 Jul 25. 59.Original research: Kirui NK, Pastakia SD, Kamano JH, Cheng S, Manuthu E, Chege P, et al. Important co-morbidity in patients with diabetes mellitus in three clinics in Western Kenya. Public Health Action. 2012;2(4):148-51. (Union-MSF course student) Drug Safety Conflicts & Humanitarian Emergencies 70.Viewpoint: Baouab TB, del Valle H, Derderian K, Ponthieu A. Looking beyond legal status to human need. Forced Migration Review. 2012;39:19-20. 71. Original research: Zachariah R, Bienvenue B, Ayada L, Manzi M, Maalim A, Engy E, et al. Practicing medicine without borders: teleconsultations and tele-mentoring for improving paediatric care in a conflict setting in Somalia? Trop Med Int Health. 2012 Sep;17(9):1156-62. 72. Original research: Coloni F, Van den Bergh R, Sittaro F, Giandonato S, Loots G, Maes P. Biodegradable bags as emergency sanitation in urban settings: the field experience. Waterlines. 2012;31(1-2):122-32. 60.Original research: Wadonda-Kabondo N, Hedt BL, van Oosterhout JJ, Moyo K, Limbambala E, Bello G, et al. A retrospective survey of HIV drug resistance among patients 1 year after initiation of antiretroviral therapy at 4 clinics in Malawi. Clin Infect Dis. 2012 May;54 Suppl 4:S355-61. 61.Original research: Chu KM, Manzi M, Zuniga I, Biot M, Ford NP, Rasschaert F, et al. Nevirapineand efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique. Int J STD AIDS. 2012 Jun;23(6):403-7. 62.Original research: Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H, Vaz P, et al. Variability of growth in children starting antiretroviral treatment in southern Africa. Pediatrics. 2012 Oct;130(4):e966-77. 63.Viewpoint: Besada D, Van Cutsem G, Goemaere E, Ford N, Bygrave H, Lynch S. The case for Option B and Optional B+: Ensuring that South Africa’s commitment to eliminating mother-to-child transmission of HIV becomes a reality. Southern African Journal of HIV Medicine. 2012;13(4):17881. 107 Sexual and Reproductive Health 66.Original research: Chu K, Cortier H, Maldonado F, Mashant T, Ford N, Trelles M. Cesarean section rates and indications in sub-Saharan Africa: a multi-country study from Medecins sans Frontieres. PLoS One. 2012;7(9):e44484. 67.Original research: Tamura M, Hinderaker SG, Manzi M, Van den Bergh R, Zachariah R. Severe acute maternal morbidity and associated deaths in confl ict and post-conflict settings in Africa. Public Health Action. 2012;2(4):122-5. (Union-MSF course student) Surgery & Anaesthesia 68.Guidelines: Sever MS, Vanholder R, Workgroup on recommendations for the management of crush victims in mass disasters. Recommendations for the management of crush victims in mass disasters. Nephrol Dial Transplant. 2012;27(Supplement 1):i1-i67. Hospitals 69. Original research: van den Boogaard W, Manzi M, Harries AD, Reid AJ. Causes of pediatric mortality and case-fatality rates in eight Médecins Sans Frontières-supported hospitals in Africa. Public Health Action. 2012;2(4):11721. (Union-MSF course student) annex of tables and data 2012 65.Original research: Tayler-Smith K, Zachariah R, Hinderaker SG, Manzi M, De Plecker E, Van Wolvelaer P, et al. Sexual violence in post-conflict Liberia: survivors and their care. Trop Med Int Health. 2012 Aug 12. (Union-MSF course student) section 21: Operational Research & Documentation 64.Original research: Tayler-Smith K, Zachariah R, Manzi M, Van den Boogaard W, Nyandwi G, Reid T, et al. Achieving the Millennium Development Goal of reducing maternal mortality in rural Africa: an experience from Burundi. Trop Med Int Health. 2012 Nov 20. MSF MEdical Department OCB section 25: Surgical Activities Table 1: Overview of OCB surgical activities per project, 2012 Mission AFG AFG AFG AFG BDI BDI COD COD COD COD Project Kabul Khost Kunduz Lashkar-Gah Gitega_OF Kabezi Lubutu Masisi Niangara Nyabiondo 1,356 1,867 352 1,242 222 1,712 705 129 Patients N° 623 55 Cases N° 690 57 3138 2329 486 1317 242 2026 806 130 Procedures N° 736 58 3,812 2,423 510 1,394 260 2,120 874 130 Mean Age Years 27 29 23 29 35 26 30 27 35 26 Female % 60.5 100.0 14.4 39.6 100.0 100.0 48.6 80.6 46.1 99.2 All trauma % 21.0 0.0 99.1 30.4 0.0 0.0 6.7 13.6 10.9 2.3 Violent trauma % 4.2 0.0 24.9 6.9 0.0 0.0 1.8 7.3 3.5 2.3 Caesarean section % 28.6 70.9 0.0 20.2 0.0 85.5 21.2 59.9 11.1 88.4 Post-op infection % ND 3.6 ND ND 5.4 3.6 ND 1.1 ND ND Primary intervention % 90.3 96.5 43.2 80.2 72.4 94.3 91.7 84.5 87.5 99.2 Emergent cases % 74.6 100.0 100.0 78.4 0.2 100.0 59.5 90.7 62.3 100.0 Minor/wound surg % 38.8 1.8 57.6 36.2 0.2 7.0 28.1 30.2 35.9 5.4 Spinal anaesthesia % 31.9 71.9 12.4 25.4 99.0 64.5 59.1 53.8 43.3 75.4 Spinal / C-Section % 84.3 92.3 NA 55.4 NA 76.5 85.1 92.9 73.1 81.6 % 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.2 0.0 1.5 min/day 114 85 383 448 122 210 206 341 128 25 Intra-Op mortality annex of tables and data 2012 section 25: Surgical Activities 108 Occupancy rate NA: not applicable; ND: no data LSO NER PAK PAK SLE SOM SOM SSD SYR Roma Dakoro Dargai Timurgara Bo Burao Guri-El Gogrial Jabal-Akkrad TOTAL 984 1,192 530 117 387 124 1,392 978 1,084 245 377 131 15,804 1046 1828 621 122 391 124 1659 1019 1246 346 652 168 20,443 1,093 1,944 637 124 396 133 1,819 1,208 1,266 386 664 223 22,210 34 31 28 27 28 31 31 25 29 22 24 26 54.9 24.4 56.4 68.4 77.5 100.0 82.8 99.4 73.9 49.0 53.8 20.6 15.9 90.1 14.2 25.6 0.5 0.8 15.9 0.3 19.7 58.0 37.9 84.0 1.2 18.2 1.1 0.9 0.0 0.0 5.5 0.2 10.0 32.7 13.8 69.5 18.3 0.0 10.6 29.1 61.5 83.1 64.6 69.4 39.1 19.2 12.7 5.3 ND 3.7 ND ND ND ND ND 2.5 0.5 ND ND ND 94.1 65.2 85.3 95.9 99.0 100.0 83.9 96.0 87.0 70.8 57.8 78.0 46.3 100.0 68.0 90.2 74.9 93.5 99.6 99.5 97.4 100.0 93.4 98.8 14.7 33.5 60.5 23.8 0.5 4.0 19.4 5.5 29.1 67.9 72.7 68.5 47.7 35.7 19.8 3.3 71.4 83.9 49.7 47.5 42.1 11.3 12.4 15.5 88.3 NA 92.9 11.8 81.9 90.3 81.5 69.4 84.7 80.9 62.5 71.4 0.2 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.6 0.3 0.0 441 494 79 62 171 49 285 188 196 91 78 85 109 IND Mon section 25: Surgical Activities HTI Tabarre annex of tables and data 2012 HTI Cange OCB Medical Activity Report 2012 MSF-OCB 94 Rue Dupré B-1090 Bruxelles Belgium Technical support & coordination Luxembourg Operational Research (LuxOR) MSF-Luxembourg 68 Rue de Gasperich Luxembourg Compilation and editing Sokhieng Au Rafael Van den Bergh Further information and reprints Dr. Rony Zachariah E-mail: rony.zachariah@brussels.msf.org Tel: + 352 332515 Fax: + 352 335133