NATIONAL LIPID ASSOCIATION SELF-ASSESSMENT PROGRAM Edition 2, 2011 Update Educational Objectives Discuss and implement the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP) III Guidelines; • Explain lipoprotein metabolism and its role in the pathogenesis of atherosclerosis; • Describe genetic disorders affecting lipoprotein metabolism and their molecular etiology; • Outline current issues and approaches to global CV risk assessment; • Manage non-lipid risk factors for dyslipidemia including hypertension, obesity, and cigarette smoking; • Identify the essential features of the therapeutic lifestyle changes approach to reducing the risk for coronary heart disease (CHD); • • Recognize the role of drug therapy in the management of dyslipidemia; Discuss mechanism of action, pharmacokinetics, side effects, and efficacy of pharmacological therapy. Volume II – Management of Cardiometabolic Risk, Biomarkers of Atherosclerosis, Epidemiology and Statistics, Clinical Trials Evaluate the use of biomarkers in the prevention and treatment of atherosclerosis; • Discuss epidemiologic and statistical evidence related to cardiovascular disease risk; • Discuss clinical trials and their role in lipid and lipoprotein treatment in cardiovascular prevention • Identify the management of dyslipidemia in special populations based on gender, culture, and disease variables; • Review experimental therapies utilized to modify dyslipidemias; • Compare alternate therapies and treatments of dyslipidemia in various populations; • Discuss the impact of dyslipidemia solutions on chronic illnesses. Volume IV – Vascular Biology, Advanced Lipid Metabolism and Lipoprotein Biochemistry • Recognize the role of macrophages and lymphocytes in atherogenesis; • Examine the role of rheology in atherosclerosis coronary artery disease; • Describe gene transfer in atherogenesis; • Explain the pathogeneses of atherosclerosis; • Interpret the interaction of platelet activation and coagulation in atherosclerotic coronary artery disease; • Identify the importance of oxidized lipoproteins in atherosclerosis; • Contrast and compare the microcirculation in atherosclerotic coronary artery disease; • Discuss the role of cytokines in the regulatory mechanism of atherosclerosis. American Board of Clinical Lipidology Volume III – Complex Case Management and Advanced Pharmacology 2011 Update Release Date: August 22, 2011 Last Updated: August 22, 2011 Expiration Date: August 21, 2013 NLA-SAP Volume I Basic Lipid and Lipoprotein Metabolism, Diagnosis & Treatment of Dyslipidemia National Lipid Association Self-Assessment Program VOLUME I Basic Lipid and Lipoprotein Metabolism, Diagnosis and Treatment of Dyslipidemia Multiple Choice Questions Critique Book Please read carefully the General Directions on pages II–III before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 Last Updated: August 15, 2011 Expiration Date: July 31, 2013 NLA-SAP Volume II Atherosclerosis, Cardiometabolic Risk, Biomarkers, Epidemiology & Statistics, Clinical Trials National Lipid Association Self-Assessment Program VOLUME II Management of Cardiometabolic Risk, Biomarkers of Atherosclerosis, Epidemiology and Statistics, Clinical Trials Multiple Choice Questions Critique Book NLA-SAP Please read carefully the General Directions on pages II–III before proceeding. Volume III Complex Case Management and Advanced Pharmacology THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 � Last Updated: August 15, 2011 � Expiration Date: July 31, 2013 � National Lipid Association Self-Assessment Program VOLUME III Complex Case Management and Advanced Pharmacology Multiple Choice Questions Critique Book Please read carefully the General Directions on the back cover before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August, 2011 � Last Updated: August, 2011 � Expiration Date: July 31, 2013 � NLA-SAP Volume IV Vascular Biology, Advanced Lipid Metabolism & Lipoprotein Biochemistry National Lipid Association Self-Assessment Program Multiple Choice Questions VOLUME IV Vascular Biology, Advanced Lipid Metabolism and Lipoprotein Biochemistry Critique Book Please read carefully the General Directions on pages II–III before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 � Last Updated: August 15, 2011 � Expiration Date: July 31, 2013 � Accreditation Council for Clinical Lipidology • 6816 Southpoint Parkway, Ste. 1000 Jacksonville, FL 32216 904.998.0854 www.lipid.org Identify the complexities of cardiometabolic risk-management in patients with the metabolic syndrome; The American Board of Clinical Lipidology (ABCL) currently offers physicians the opportunity for certification and appropriate recognition of advanced training and experience managing patients with lipid disorders. The application and certifying process for physicians can be found at www.lipidboard.org. • The Accreditation Council for Clinical Lipidology (ACCL) is an independent certifying organization that has developed standards and examinations in the field of lipidology for the growing number of allied health, primary care, and paraprofessionals who are involved in lipid management. Applications and certifying processes for the ACCL’s exams can be found at www.lipidspecialist.org. • Order the NLA Self-Assessment Program Edition 2, 2011 Update Online at www.lipid.org/sap Volume I – Basic Lipid and Lipoprotein Metabolism, Diagnosis and Treatment of Dyslipidemia The NLA-SAP series is a comprehensive, interactive clinical problem-solving program that validates, strengthens and reinforces your knowledge of the core curriculum of clinical lipidology. • Each volume of the NLA-SAP provides between 32-40 hours of CME/CE credit. • The program provides a critical assessment of your strengths and weaknesses to guide you in the selection of additional CME training courses. The NLA-SAP serves as both a review and a resource to prepare for certification in clinical lipidology. • Learn from the experience of leading practitioners, clinical researchers and experts in lipidology. • Complete the NLA-SAP anywhere—no travel or lodging costs and no time away from your patients and family. This program is endorsed by the Preventive Cardiovascular Nurses Association Topics Covered 1. E/CE 32 CM its d Cre Volume I Basic Lipid and Lipoprotein Metabolism, Diagnosis and Treatment of Dyslipidemia National Lipid Association Self-Assessment Program • National Cholesterol Education Program Adult Treatment Panel (NCEP ATP) III Guidelines • Lipoprotein metabolism • Genetic disorders affecting lipoprotein metabolism • Current issues and approaches to global CV risk assessment • Non-lipid risk factors for dyslipidemia • Therapeutic lifestyle changes • Pharmacological therapy NLA-SAP Volume I Basic Lipid and Lipoprotein Metabolism, Diagnosis & Treatment of Dyslipidemia Assess your knowledge You’ll receive a Question book consisting of clinical, problem solving multiple choice questions and multiple true-false questions. The questions will objectively validate your relevant clinical knowledge and assess your ability to accurately diagnose and manage patients with complex lipid disorders. Multiple Choice Questions Critique Book 2 Complete the answer sheet Fill out the answer sheet provided in your Question book and return within two months. 3. Get your score report Your personalized score report will provide a detailed outline of your performance, including your total score, a list of the items you answered incorrectly, the correct answer for those items, and the percent of all participants who answered those items correctly. Please read carefully the General Directions on pages II–III before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 Last Updated: August 15, 2011 Expiration Date: July 31, 2013 Volume II 4. E/CE 35 CM its Cred Management of Cardiometabolic Risk, Biomarkers of Atherosclerosis, Epidemiology and Statistics, Clinical Trials • Cardiometabolic risk management • Biomarkers • Epidemiologic and statistical evidence • Clinical trials NLA-SAP Volume II Atherosclerosis, Cardiometabolic Risk, Biomarkers, Epidemiology & Statistics, Clinical Trials National Lipid Association Self-Assessment Program Multiple Choice Questions Critique Book 5. Review the Educational (Learning) Critique The Educational Critique book contains detailed explanations for the correct and incorrect answers for the questions based on the most current, peer-reviewed published information to immediately help you to 1) strengthen the weak areas identified in the confidential score reports, and 2) reinforce positive areas of knowledge and understanding. Request CME/CE Credit For each program you complete, you’ll receive a Certificate of Participation and a CME/CE credit for a maximum of 32–40 hours. The credit hours earned by your participation meet the credentialing and certification standards established by the American Board of Clinical Lipidology and the Accreditation Council for Clinical Lipidology. Please read carefully the General Directions on pages II–III before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 � Last Updated: August 15, 2011 � Expiration Date: July 31, 2013 � NLA-SAP Faculty 2011 Update Volume III Complex Case Management and Advanced Pharmacology • Special populations • Experimental therapies • Alternate therapies • Dyslipidemia solutions for chronic illnesses Volume IV Vascular Biology, Advanced Lipid Metabolism and Lipoprotein Biochemistry • Macrophages and lymphocytes • Rheology • Gene transfer • Pathogenesis of atherosclerosis • Platelet activation and coagulation • Oxidized lipoproteins • Microcirculation • Cytokines NATIONAL LIPID ASSOCIATION SELF-ASSESSMENT PROGRAM Edition 2, 2011 Update How the Self-Assessment Program Works E/CE 35 CM its Cred NLA-SAP Volume III Complex Case Management and Advanced Pharmacology National Lipid Association Self-Assessment Program Multiple Choice Questions Critique Book Please read carefully the General Directions on the back cover before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August, 2011 � Last Updated: August, 2011 � Expiration Date: July 31, 2013 � E/CE 40 CM its d e r C NLA-SAP Volume IV Vascular Biology, Advanced Lipid Metabolism & Lipoprotein Biochemistry National Lipid Association Self-Assessment Program Multiple Choice Questions Critique Book Please read carefully the General Directions on pages II–III before proceeding. THE NATIONAL LIPID ASSOCIATION Release Date: August 15, 2011 � Last Updated: August 15, 2011 � Expiration Date: July 31, 2013 � Chair Carl E. Orringer, MD, FNLA* Harrington-McLaughlin Chair in Preventive Cardiovascular Medicine Associate Professor of Medicine Case Western Reserve University School of Medicine Cleveland, OH NLA-SAP Medical Director Michael H. Davidson, MD, FACC, FACP, FNLA* Clinical Professor Director of Preventive Cardiology The University of Chicago Pritzker School of Medicine Chicago, IL NLA-SAP Managing Editor Dante S. LaRocca, PhD President/CEO Professional Evaluation, Inc. (PEI) Contributing Faculty The NLA-SAP Edition 2, 2011 Update includes content originally written, developed, and published in August 2008 by over 40 reputable faculty members of the NLA. The NLA wishes to acknowledge their contributions to the NLA-SAP. For a complete list of contributing faculty, visit www.lipid.org/sap. Featured Faculty Harold E. Bays, MD, FACP, FNLA* President and Medical Director L-MARC Research Center Louisville, KY Vera A. Bittner, MD, MSPH, FNLA* Professor of Medicine Section Head, Preventive Cardiology Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham, AL Quantity Volume I Member Peter P. Toth, MD, PhD, FAAFP, FAHA, FCCP, FACC, FNLA* Director of Preventive Cardiology Sterling Rock Falls Clinic, Ltd. Chief of Medicine, CGH Medical Center Sterling, IL Clinical Professor University of Illinois School of Medicine Peoria, IL *NLA SAPs are only shipped within the United States and Canada. Non-Member** Total $125 $175 $ Volume II $125 $175 $ Volume III $125 $175 $ Volume IV $125 $175 $ 4-Volume Set $500 $700 $ UPS Ground shipping (4–5 business days): $15 $ UPS Express shipping (3–4 business days): $30 $ Name (First) Total Enclosed $ (MI) Last Degree Address Shipping Address City E-mail Check MasterCard State Postal Code *Country Phone Number VISA Card # AmEx Exp date Name on card Signature of cardholder By Mail National Lipid Association 6816 Southpoint Pky, Ste. 1000 Jacksonville, FL 32216 By Fax (Credit card orders only) 904.998.0855 Target Audience For Volumes I-IV Lipidologists, Cardiologists, Endocrinologists, Nephrologists, Primary Care Physicians, Internists, Family Practitioners, PhDs, Physicians Assistants, Cardiovascular Nurses, Pharmacists, and Dietitians. CME credit provided by the National Lipid Association Joseph J. Saseen, PharmD, CLS, FNLA Professor Departments of Clinical Pharmacy and Family Medicine University of Colorado Anschutz Medical Campus School of Pharmacy Aurora, CO *Denotes Diplomate, American Board of Clinical Lipidology Order Online at www.lipid.org/sap Upon payment, orders are fulfilled within 2–3 days (not including shipping). Physicians The National Lipid Association (NLA) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The NLA designates these enduring activities: Volume I for a maximum of 32 AMA PRA Category 1 Credit(s)™; Volume II for a maximum of 35 AMA PRA Category 1 Credit(s)™ ; and Volume III for a maximum of 35 AMA PRA Category1 Credit(s)™; and Volume IV for a maximum of 35 AMA PRA Category 1 Credit(s)™ . Physicians should only claim credit commensurate with the extent of their participation in the activity. Physician Assistants NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME. CE credit provided by AKH Inc., Advancing Knowledge in Healthcare Pharmacists AKH Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. These application-based activities are approved for: Volume I for a maximum of 32 contact hours (3.2 CEUs) UAN 0077-9999-11-040-H04-P; Volume II for a maximum of 35 contact hours (3.5 CEUs) UAN 0077-9999-11-041-H04-P; Volume III for a maximum of 35 contact hours (3.5 CEUs) UAN 0077-9999-11-042-H04-P; and Volume IV for a maximum of 40 contact hours (4.0 CEUs) UAN 0077-9999-11-043-H04-P. Initial Release date for Volumes I-IV: 08/22/2011. Date Online (Credit card orders only) www.lipid.org/sap Nurses AKH Inc. is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s COA. AKH Inc. designates these educational activities for 32 contact hours (3.2 CEUs) for Volume I; 35 contact hours (3.5 CEUs) for Volume II; 35 contact hours (3.5 CEUs) for Volume III; and 40 contact hours (4.0 CEUs) for Volume IV. Accreditation applies solely to educational activities and does not imply approval or endorsement of any commercial product by the ANCC-COA. Dietitians AKH Inc. is a Continuing Professional Education (CPE) Accredited Provider with the Commission on Dietetic Registration (CDR). Registered dietitians (RDs) and dietetic technicians, registered (DTRs) will receive 32 continuing professional education units (CPEUs) for completion of Volume I; 35 continuing professional education units (CPEUs) for completion of Volume II; 35 continuing professional education units (CPEUs) for completion of Volume III; and 40 continuing professional education units (CPEUs) for completion of Volume IV. CDR Accredited Provider #AN008. The focus of these activities is rated Level 3. Learners may submit evaluations of program/materials quality to the CDR at www.cdrnet.org. Criteria for Success In order to receive credit for this enduring monograph, participants should read the entire monograph, complete and submit answer sheets and evaluation. A statement of credit will be mailed/e-mailed to participants 4-6 weeks after successful completion. If you have questions about this CME/CE activity, please contact the NLA at cme@lipid.org. Commercial Support for Volumes I-IV No commercial support was received for these activities. NLASAP0811