Material Safety Data Sheet AMYLASE Carolina Biological Supply Company Page 1 of 1 1. PRODUCT DESCRIPTION Product Name: Amylase Product Code(s): Various Size: Various Chemical Name: None known. CAS Number: 9000-90-2 Formula: No information available. Synonyms: alpha-1, 4-glucan, 4-glucanohydrolase Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 2. COMPOSITION/INFORMATION ON INGREDIENTS Principal Components: Amylase TLV and PEL units: None 3. HAZARD IDENTIFICATION To the best of our knowledge, this product is not considered hazardous as defined by the OSHA Hazard Communication Standard. However, Carolina Biological is providing an abbreviated MSDS containing general information about this chemical. Revised 6/8/09 4. SPECIAL PROTECTION INFORMAtiON Respiratory Protection (Specify Type): None needed under normal conditions of use. Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety goggles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eyewash, and safety shower. 5. FIREFIGHTING PROCEDURES Extinguisher Media: Use media suitable to extinguish surrounding fire. 6. DISPOSAL INFORMATION Dilute with water and dispose into a sanitary sewer system. Material Safety Data Sheet BENEDICT’S SOLUTION, QUALITATIVE Carolina Biological Supply Company Page 1 of 2 Revised 6/8/09 1. PRODUCT DESCRIPTION 5. FIREFIGHTING PROCEDURES Product Name: Benedict’s Solution, Qualitative Product Code(s): Various Size: Various Chemical Name: Does not apply product is a mixture CAS Number: None assigned to this mixture–see individual elements below Formula: See section 2 Synonyms: None known Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 Flash Point (Method Used): Not flammable. NFPA Rating: None established Extinguisher Media: Use media suitable to extinguish surrounding fire. Flammable Limits in Air % by Volume: Not applicable. Autoignition Temperature: No data available. Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus. Unusual Fire and Explosion Hazards: Slight fire hazard, may emit toxic fumes when heated to decomposition. 2. COMPOSITION/INFORMATION ON INGREDIENTS Principal Hazardous Components: Cupric Sulfate: (CAS# 7758-98-1) 1.5% Sodium Citrate: (CAS# 68-04-2) 15.1% Sodium Carbonate: (CAS# 497-19-8) 8.7% Water: Balance TLV and PEL Units: Cupric Sulfate: ACGIH TLV 1 mg/m3 TWA (dust and mist– Copper) OSHA-PEL 1 mg/m3 TWA (dust and mist – Copper) Sodium Citrate: No TLV (ACGIH) or PEL (OSHA) information found. Sodium Carbonate: No TLV (ACGIH) or PEL (OSHA) information found. 3. HAZARD IDENTIFICATION Potential Health Effects: Eyes: May cause irritation. Skin: May cause irritation. Ingestion: May cause gastrointestinal discomfort. Inhalation: May cause irritation to respiratory tract. 4. FIRST AID MEASURES Emergency and First Aid Procedures Eyes: Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention at once. Skin: Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention at once. Ingestion: If swallowed, if conscious, give some water. Do not induce vomiting unless and until directed by medical personnel. Get medical attention immediately. Never give anything by mouth to an unconscious person. Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet, and get medical attention. 6. SPILL OR LEAK PROCEDURES Steps to be Taken in Case Material is Released or Spilled: Ventilate area of spill. Eliminate all sources of ignition. Remove all non-essential personnel from area. Clean-up personnel should wear proper protective equipment and clothing. Absorb material with suitable absorbent and containerize for disposal. 7. SPECIAL PRECAUTIONS Precautions to be Taken in Handling or Storing: Keep in tightly closed container in a cool place away from acid and acid fumes. Do not get in eyes, on skin or on clothing. Do not breathe mist. Other Precautions: Do not take internally. Wash hands thoroughly after handling. 8. SPECIAL PROTECTION INFORMATION Respiratory Protection (Specify Type): A NIOSH/MSHA chemical cartridge respirator should be worn if PEL or TLV is exceeded. Ventilation: Local Exhaust: Yes Mechanical (General): Yes Special: No Other: No Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety googles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower. Material Safety Data Sheet BENEDICT’S SOLUTION, QUALITATIVE(cont.) Carolina Biological Supply Company Page 2 of 2 9. PHYSICAL DATA Molecular Weight: No data available Melting Point: No data available Boiling Point: Approximately 110°C-120°C Vapor Pressure: Not established Vapor Density (Air=1): 0.7 (water) Specific Gravity (H20=1): 1.145 at 20°C Percent Volatile by Volume: N/A Evaporation Rate (H20=1): No data available Solubility in Water: Complete in all proportions Appearance and Odor: Light blue solution with no odor 10. REACTIVITY DATA Stability: Stable Conditions to Avoid: High temperature, excess heat Incompatibility (Materials to Avoid): Acids and strong oxidizers Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrous oxides, sulfur oxides Hazardous Polymerization: Will not occur 11. TOXICITY DATA Toxicity Data: To the best of our knowledge, the toxicological properties of this mixture have not been thoroughly evaluated. Data is listed for individual components. All data RTECS,1993. Cupric Sulfate: Oral Rat LD50: 300 mg/kg Sodium Citrate: Information not available Sodium Carbonate: Oral Rat LD50: 4090 mg/kg Effects of Overexposure: Acute: See section 3 Chronic: Cupric Sulfate: Mutation data cited. Reproductive effects data cited. Tumorigenic data cited. Not listed as causing cancer by IARC, NTP, or OSHA. Sodium Citrate: No chronic effects data found. Not listed as causing cancer by IARC, NTP, or OSHA. Sodium Carbonate: Reproductive effects data cited. Not listed as causing cancer by IARC, NTP, or OSHA. Conditions Aggravated by Overexposure: No data available. Target Organs: No data available. Primary Route(s) of Entry: Inhalaition. 12. ECOLOGICAL DATA EPA Waste Numbers: None 13. DISPOSAL INFORMATION Waste Disposal Methods: Dispose in accordance with all applicable federal, state and local regulations. Always contact a permitted waste disposer (TSD) to assure compliance. Revised 6/8/09 14. TRANSPORT INFORMATION Not regulated for transport. 15. REGULATORY INFORMATION EPA TSCA Status: On TSCA Inventory Hazard Category for SARA section 311/312 Reporting: Acute SARA Sec. 313 SARA EHS Product or Components Sec. 302 TPQ Chemicals CERCLA Name List Chemical Sec. 103 Category RQ lbs. RCRA Sec. 261.33 Cupric Sulfate No No Copper 10 No Sodium Citrate No No No No No Sodium Carbonate No No No No No 16. ADDITIONAL INFORMATION The information provided in this Matieral Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the Matieral Safety Data sheet. Any employer must carefully assess the applicability of any information contained herein in regards to the particular use to which the employer puts the material. Glossary ACGIH American Conference of Governmental Industrial Hygienists CAS Number Chemical Abstract Services Number CERCLA Comprehensive Environmental Response, Compensation, and Liability Act DOT U.S. Department of Transportation IARC International Agency of Research on Cancer N/A Not Available NTP National Toxicology Program OSHA Occupational Safety and Health Administration PEL Permissible Exposure Limit ppm parts per million RCRA Resource Conservation and Recovery Act SARA Superfund Amendments and Reauthorization Act TLV Threshold Limit Value TSCA Toxic Substances Control Act Material Safety Data Sheet GASTRIC JUICE, ARTIFICIAL Carolina Biological Supply Company Page 1 of 1 1. PRODUCT DESCRIPTION Product Name: Gastric Juice, Artificial Product Code(s): Various Size: Various Chemical Name: None Synonyms: None Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 2. HAZARD IDENTIFICATION Revised 6/8/09 4. SPECIAL PROTECTION INFORMATION Respiratory Protection (Specify Type): None needed under normal conditions of use. Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety goggles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eyewash, and safety shower. Unusual Fire and Explosion Hazards: Thermal decomposition produces highly toxic fumes. Explosive reaction with potassium chlorate or bromine trifluoride. Violent reaction (ignition) with bromine pentafluoride, NH4, NO3, and IF7. 5. FIREFIGHTING PROCEDURES Extinguisher Media: Use media suitable to extinguish surrounding fire. To the best of our knowledge, this product is not considered hazardous as defined by the OSHA Hazard Communication Standard. However, Carolina Biological is providing an 6. DISPOSAL INFORMATION abbreviated MSDS containing general information about this Waste Disposal Methods: Dispose in accordance with all chemical. applicable Federal, State and Local regulations. Eyes: Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists. Skin: Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists. Ingestion: If swallowed, if conscious, give plenty of water. Immediately call a physician or poison control center. Never give anything by mouth to an unconscious person. Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm, quiet, and get medical attention. 3. SPILL OR LEAK PROCEDURES Steps to be Taken in Case Material is Released or Spilled: Ventilate area of spill. Eliminate all sources of ignition. Remove all non-essential personnel from area. Clean-up personnel should wear proper protective equipment and clothing. Absorb material with suitable absorbent and containerize for disposal. Material Safety Data Sheet HYDROCHLORIC ACID, 0.1 M, 0.07 M, AND 1 M Carolina Biological Supply Company Page 1 of 2 Revised 6/8/09 1. PRODUCT DESCRIPTION 5. FIREFIGHTING PROCEDURES Product Name: Hydrochloric Acid, 0.1 M; Hydrochloric Acid, 1 M; Hydrochloric Acid, 0.07 M Product Code(s): Various Size: Various Chemical Name: Hydrochloric Acid CAS Number: 7647-01-0 Formula: HCI Synonyms: Muriatic Acid Solution, Hydrochloric Acid 0.1N and 1N Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 Flash Point (Method Used): Non-combustible. NFPA Rating: Heath: 1 Flammability: 0 Reactivity: 0 Extinguisher Media: Water spray Flammable Limits in Air % by Volume: No data available Autoignition Temperature: No data available. Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus. Unusual Fire and Explosion Hazards: None cited. 2. COMPOSITION/INFORMATION ON INGREDIENTS Principal Hazardous Components: Hydrochloric Acid (CAS# 7647-01-0) < 4% TLV and PEL Units: OSHA-PEL 5 ppm ceiling—ACGIH-TLV 5 ppm ceiling 3. HAZARD IDENTIFICATION Emergency Overview: May irritate skin, eyes, respiratory tract, digestive tract. Potential Health Effects: Eyes: May cause irritation. Skin: May cause irritation. Ingestion: May cause gastrointestinal discomfort. Inhalation: May cause irritation to respiratory tract. 4. FIRST AID MEASURES Emergency and First Aid Procedures Eyes: Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists. Skin: Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persits. Ingestion: Do not induce vomiting. If swallowed, if conscious give plenty of water immediately and call a physician or poison control center. Never give anything by mouth to an unconscious person. Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet, and get medical attention. 6. SPILL OR LEAK PROCEDURES Steps to be Taken in Case Material is Released or Spilled: Ventilate area of spill. Eliminate all sources of ignition. Remove all non-essential personnel from area. Clean-up personnel should wear proper protective equipment and clothing. Absorb material with suitable absorbent and containerize for disposal. 7. SPECIAL PRECAUTIONS Precautions to be Taken in Handling or Storing: Keep container tightly closed in a cool, dry, well-ventilated area away from incompatible materials. Other Precautions: Handle empty containers with caution. 8. SPECIAL PROTECTION INFORMATION Respiratory Protection (Specify Type): A NIOSH/MSHA chemical cartridge respirator should be worn if PEL or TLV is exceeded. Ventilation: Local Exhaust: Yes Mechanical (General): Yes Special: No Other: No Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety googles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower. Material Safety Data Sheet HYDROCHLORIC ACID, 0.1 M, 0.07 M, AND 1 M(cont.) Carolina Biological Supply Company Page 2 of 2 Revised 6/8/09 9. PHYSICAL DATA 14. TRANSPORT INFORMATION Molecular Weight: Not applicable to this solution Melting Point: Approximately -0.1°C Boiling Point: 99.9°C Vapor Pressure (mmHg): N/A Vapor Density (Air=1): N/A Specific Gravity (H20=1): N/A Percent Volatile by Volume: 99.9+ Evaporation Rate (BuAc=1): 0.36 Solubility in Water: Miscible Appearance and Odor: Clear, colorless liquid with an acrid odor. Hydrochloric acid, solution 10. REACTIVITY DATA Stability: Stable Conditions to Avoid: Heat, contact with metals Incompatibility (Materials to Avoid): Bases, alkalis, and amines. Hazardous Decomposition Products: Toxic hydrogen chloride gas. Hazardous Polymerization: Will not occur 11. TOXICITY DATA Toxicity Data: For this solution, not known. Effects of Overexposure: Acute: See section 3 Chronic: Tests on laboratory animals indicate material may produce adverse mutagenic and reproductive effects. Conditions Aggravated by Overexposure: Respiratory conditions. Target Organs: No data available. Primary Route(s) of Entry: Inhalation, ingestion, or skin contact. 12. ECOLOGICAL DATA EPA Waste Numbers: D002 13. DISPOSAL INFORMATION Waste Disposal Methods: Dispose in accordance with all applicable federal, state and local regulations. Always contact a permitted waste disposer (TSD) to assure compliance. 15. REGULATORY INFORMATION EPA TSCA Status: On TSCA Inventory Hazard Category for SARA section 311/312 Reporting: Acute SARA Sec. 313 SARA EHS Product or Components Hydrochloric Acid Sec. 302 TPQ 500 Chemicals CERCLA Name List Yes Chemical Sec. 103 Category RQ lbs. No 5000 RCRA Sec. 261.33 No 16. ADDITIONAL INFORMATION The information provided in this Matieral Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the Matieral Safety Data sheet. Any employer must carefully assess the applicability of any information contained herein in regards to the particular use to which the employer puts the material. Glossary ACGIH American Conference of Governmental Industrial Hygienists CAS Number Chemical Abstract Services Number CERCLA Comprehensive Environmental Response, Compensation, and Liability Act DOT U.S. Department of Transportation IARC International Agency of Research on Cancer N/A Not Available NTP National Toxicology Program OSHA Occupational Safety and Health Administration PEL Permissible Exposure Limit ppm parts per million RCRA Resource Conservation and Recovery Act SARA Superfund Amendments and Reauthorization Act TLV Threshold Limit Value TSCA Toxic Substances Control Act Material Safety Data Sheet LUGOL SOLUTION Carolina Biological Supply Company Page 1 of 2 Revised 6/8/09 1. PRODUCT DESCRIPTION 5. FIREFIGHTING PROCEDURES Product Name: Lugol Solution Product Code(s): Various Size: Various Chemical Name: Product is a mixture CAS Number: See Section 2 Formula: See Section 2 Synonyms: Donaldson’s Amoeba Stain 2 Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 Flash Point (Method Used): No information available. NFPA Rating: None established Extinguisher Media: Use dry chemical, CO2 or appropriate foam. Flammable Limits in Air % by Volume: No information available. Autoignition Temperature: No information available. Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus. Unusual Fire and Explosion Hazards: When heated to excessive temperatures may emit toxic and corrosive fumes of iodine. 2. COMPOSITION/INFORMATION ON INGREDIENTS Principal Hazardous Components: Potassium Iodide: (CAS# 7681-11-0) 10% Iodine: (CAS# 7553-56-2) 5% TLV and PEL Units: Potassium Iodide: No information found Iodine: ACGIH-TLV Ceiling 0.1 ppm (TWA) OSHA-PEL Ceiling 0.1 ppm, Ceiling 1 mg/m3 3. HAZARDOUS IDENTIFICATION Emergency Overview: Harmful if swallowed, inhaled or absorbed through the skin. May cause irritation to eyes, skin and mucous membranes. Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Potential Health Effects: Eyes: May cause irritation. Skin: May cause irritation. Ingestion: May cause gastrointestinal discomfort. Inhalation: May cause irritation to respiratory tract. 4. FIRST AID MEASURES Emergency and First Aid Procedures Eyes: Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists. Skin: Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists. Ingestion: If swallowed, if conscious, give plenty of water to dilute, and get medical attention immediately. Never give anything by mouth to an unconscious person. Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet, and get medical attention. 6. SPILL OR LEAK PROCEDURES Steps to be Taken in Case Material is Released or Spilled: Ventilate area of spill. Eliminate all sources of ignition. Remove all non-essential personnel from area. Clean-up personnel should wear proper protective equipment and clothing. Absorb material with suitable absorbant and containerize for disposal. 7. SPECIAL PRECAUTIONS Precautions to be Taken in Handling or Storing: Store tightly closed in a cool, dry, well ventilated area away from incompatible materials. Suitable for storage in any general chemical storage area. 8. SPECIAL PROTECTION INFORMATION Respiratory Protection (Specify Type): A NIOSH/MSHA chemical cartridge respirator should be worn if PEL or TLV is exceeded. Ventilation: Local Exhaust: Preferred Mechanical (General): Acceptable Special: No Other: No Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety goggles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower. Material Safety Data Sheet LUGOL SOLUTION (cont.) Carolina Biological Supply Company Page 2 of 2 9. PHYSICAL DATA Molecular Weight: No data available Melting Point: No data available Boiling Point: Approximately 100°C Vapor Pressure: Approximately 17.535 @ 20°C Vapor Density (Air=1): No information available. Specific Gravity (H2O=1): 1.0 Percent Volatile by Volume: 98% Evaporation Rate (H2O=1): 1 Solubility in Water: Complete, product is aqueous solution Appearance and Odor: Deep amber liquid with characteristic odor of iodine. 10. REACTIVITY DATA Stability: Stable Conditions to Avoid: High temperatures or excessive heat. Incompatibility (Materials to Avoid): Contact with ammonia fumes may cause formation of explosive nitroiodide. Hazardous Decomposition Products: Free iodine Hazardous Polymerization: Will not occur 11. TOXICITY DATA Toxicity Data: Mixture has not been thoroughly evaluated. Data is listed for individual components. Potassium Iodide: Oral Mouse LDLo: 1862 mg/kg Iodine: Oral Rat LD50: 14g/kg Effects of Overexposure: Acute: See section 3 Chronic: Potassium Iodide and Iodine: Mutation data cited. Reproductive data cited. Not listed as causing by IARC, NTP, or OSHA Conditions Aggravated by Overexposure: Preexisting conditions of the eyes, skin, nose and throat. Target Organs: No information available. Primary Route(s) of Entry: Inhalation, ingestion, irritation in eyes or skin contact. 12. ECOLOGICAL DATA EPA Waste Numbers: None 13. DISPOSAL INFORMATION Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Always contact a permitted waste disposer (TSD) to assure compliance. Revised 6/8/09 14. TRANSPORT INFORMATION DOT Proper Shipping Name: Not regulated for transport. 15. REGULATORY INFORMATION EPA TSCA Status: On TSCA Inventory Hazard Category for SARA section 311/312 Reporting: Acute SARA Sec. 313 Chemicals CERCLA SARA EHS Product or Components Sec. 302 TPQ Potassium Iodide Iodine Name List Chemical Sec. 103 Category RQ lbs. RCRA Sec. 261.33 No No No No No No No No No No 16. ADDITIONAL INFORMATION The information provided in this Matieral Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the Matieral Safety Data sheet. Any employer must carefully assess the applicability of any information contained herein in regards to the particular use to which the employer puts the material. Glossary ACGIH American Conference of Governmental Industrial Hygienists CSA Number Chemical Services Abstract Number CERCLA Comprehensive Environmental Response, Compensation, and Liability Act DOT U.S. Department of Transportation IARC International Agency of Research on Cancer N/A Not Available NTP National Toxicology Program OSHA Occupational Safety and Health Administration PEL Permissible Exposure Limit ppm parts per million RCRA Resource Conservation and Recovery Act SARA Superfund Amendments and Reauthorization Act TLV Threshold Limit Value TSCA Toxic Substances Control Act Material Safety Data Sheet PEPSIN Carolina Biological Supply Company Page 1 of 2 Revised 6/8/09 1. PRODUCT DESCRIPTION 5. FIREFIGHTING PROCEDURES Product Name: Pepsin Product Code(s): Various Size: Various Chemical Name: Pepsin CAS Number: 9001-75-6 Formula: Pepsin Synonyms: None known Distributor: Carolina Biological Supply Company 2700 York Road Burlington, NC 27215 Chemical Emergency Information: 800-227-1150 (8am-5pm [ET] M-F) Chemtrec (Transportation Spill Response 24 hours): 800-424-9300 Flash Point (Method Used): None NFPA Rating: Health: 1 Fire: 1 Reactivity: 0 Extinguisher Media: Use dry chemical, CO2 or appropriate foam. Flammable Limits in Air % by Volume: No data available. Autoignition Temperature: No data available. Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH-approved self-contained breathing apparatus. Unusual Fire and Explosion Hazards: Avoid inhalation of combustion fumes. 2. COMPOSITION/INFORMATION ON INGREDIENTS Principal Hazardous Components: Pepsin (CAS# 9001-75-6) 100% TLV and PEL Units: None established 3. HAZARD IDENTIFICATION Emergency Overview: Handling care generally in keeping with safe laboratory practices is recommended. Potential Health Effects: Eyes: May cause irritation. Skin: May cause irritation. Ingestion: May cause gastrointestinal discomfort. Inhalation: May cause irritation to respiratory tract. 4. FIRST AID MEASURES Emergency and First Aid Procedures Eyes: Flush thoroughly with water. Seek medical attention if irritation persists. Skin: Wash exposed area with soap and water. Seek medical attention if irritation persists. Ingestion: In quantities normally handled, symptoms would not be expected. If swallowed, if conscious, give water. Seek medical attention if gastrointestinal irritation or other unexpected symptoms develop. Inhalation: Not expected to present a problem. However, if the exposed person is having trouble breathing, remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration of breathing has stopped. Keep person warm and quiet, and get medical attention. 6. SPILL OR LEAK PROCEDURES Steps to be Taken in Case Material is Released or Spilled: Ventilate area of spill. Clean-up personnel should wear proper protective equipment. Avoid creating dust. Sweep or scoop up and containerize for disposal. 7. SPECIAL PRECAUTIONS Precautions to be Taken in Handling or Storing: Store tightly closed in a cool, dry area. Avoid contact with eyes, skin, and clothing. Other Precautions: Avoid exposing products to high humidity conditions. Wash thoroughly with soap and water after handling. 8. SPECIAL PROTECTION INFORMATION Respiratory Protection (Specify Type): A NIOSH/MSHA chemical cartridge respirator should be worn if PEL or TLV is exceeded. Ventilation: Local Exhaust: Preferred Mechanical (General): Acceptable Special: No Other: No Protective Gloves: Rubber, neoprene, PVC, or equivalent. Eye Protection: Splash-proof chemical safety goggles should be worn at all times. Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower. Material Safety Data Sheet PEPSIN (cont.) Carolina Biological Supply Company Page 2 of 2 9. PHYSICAL DATA Molecular Weight: No information available. Melting Point: Decomposes Boiling Point: No information available. Vapor Pressure: No information available. Vapor Density (Air-1): No information available. Specific Gravity (H2O=1): No information available. Percent Volatile by Volume: No information available. Evaporation Rate (H2O=1): No information available. Solubility in Water: Soluble Appearance and Odor: Yellowish powder, slightly acid taste. Characteristic odor. 10. REACTIVITY DATA Stability: Stable Conditions to Avoid: Heat Incompatibility (Materials to Avoid): Alcohol, tannin, alkaline substances, salts of heavy metals, strong oxidizing agents. Hazardous Decomposition Products: COx, NOx Hazardous Polymerization: Will not occur 11. TOXICITY DATA Toxicity Data: No toxicity data found Effects of Overexposure: Acute: See section 3 Chronic: Mutation data cited. Not listed as causing cancer by IARC, NTP, or OSHA Conditions Aggravated by Overexposure: Hypersensitivity to material: dermatology problems. Target Organs: Skin Primary Route(s) of Entry: None cited 12. ECOLOGICAL DATA EPA Waste Numbers: None 13. DISPOSAL INFORMATION Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Always contact a permitted waste disposer (TSD) to assure compliance. Revised 6/8/09 14. TRANSPORT INFORMATION Non-regulated material 15. REGULATORY INFORMATION EPA TSCA Status: On TSCA Inventory Hazard Category for SARA section 311/312 Reporting: Acute SARA Sec. 313 SARA EHS Chemicals CERCLA RCRA Product or Components Pepsin Sec. 302 TPQ No Name List No Chemical Sec. 103 Category RQ lbs. No No Sec. 261.33 No 16. ADDITIONAL INFORMATION The information provided in this Matieral Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the Matieral Safety Data sheet. Any employer must carefully assess the applicability of any information contained herein in regards to the particular use to which the employer puts the material. Glossary ACGIH American Conference of Governmental Industrial Hygienists CSA Number Chemical Abstract Services Number CERCLA Comprehensive Environmental Response, Compensation, and Liability Act DOT U.S. Department of Transportation IARC International Agency of Research on Cancer N/A Not Available NTP National Toxicology Program OSHA Occupational Safety and Health Administration PEL Permissible Exposure Limit ppm parts per million RCRA Resource Conservation and Recovery Act SARA Superfund Amendments and Reauthorization Act TLV Threshold Limit Value TSCA Toxic Substances Control Act