Mistakes Meiosis.notebook February 17, 2014 Mistakes in Meiosis Nondisjuntion ­ failure of chromosomes to separate properly Feb 15­7:39 AM Leads to conditions like…. 1. Trisomy ­ extra chromosomes Ex: trisomy 21 ­ individual has three chromosome # 21’s in their body cells = Down’s syndrome How many total chromosomes would this individual have in their body cells? _47_____ Feb 15­7:44 AM 1 Mistakes Meiosis.notebook February 17, 2014 2. Monosomy ­ missing a chromosome Example: Turner Syndrome ­ human female with one X sex chromosome instead of XX (XX = Female XY = Male) Turners Female = X_ The other X is missing Feb 15­7:46 AM 3. Polyploid ­ homologous chromosomes do not separate at all. Rare in animals, common in plants. Ex: The extra sets of chromosomes in plants makes larger fruit and flowers and healthier plants ­ great economic value! Metaphase of meiosis 1 XX XX XX XX None Feb 15­7:47 AM 2 Mistakes Meiosis.notebook February 17, 2014 Feb 15­7:55 AM Question: Which would be worse…a chromosomal mistake in the gamete (sex cell) or a mistake in a somatic (body cell) cell? Definitely a gamete because it controls the whole organism's genetics and not just an individual body part. Feb 15­8:00 AM 3 Mistakes Meiosis.notebook February 17, 2014 Karyotyping Picture of chromosomes arranged in • homologous pairs. Starts from largest to smallest. • Sex chromosomes shown last • Feb 15­8:01 AM Sex chromosomes ­ One pair per person XX­ female XY = male Autosomes ­ humans have 22 pairs of homologous non­sex chromosomes Feb 15­8:02 AM 4 Mistakes Meiosis.notebook February 17, 2014 Karyotopes Showing Nondisjuntion Feb 15­8:04 AM 5