MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
MATERIAL SAFETY DATA SHEET
READ AND UNDERSTAND MATERIAL SAFETY DATA SHEET BEFORE HANDLING OR DISPOSAL OF PRODUCT
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
1.1 Material Identity / Product identifier:
Chemical name:
Synonyms:
Maleic Anhydride
Maleic Anhydride
2,5- Furandione; Toxilic anhydride;
dioxofuran
cis-Butenedioic anhydride;
Dihydro-2,5-
Structural Formula:
C4H2 O
CAS Registry Number:
108-31-6
UN/NA Number (s):
2215
Chemical Name and/ or Family or Description:
Chemical Family:
Unsaturated aliphatic carboxylic acid anhydride / alkenoic acid anhydride /
alkene dioic acid anhydride.
1.2 Relevant identified uses of the substance or mixture:
Unsaturated polyester resin, alkyd resin manufacture, production of plasticizers,
among others
1.3 Company Information
Company name:
RETER COMERCIALIZADORA DE PRODUCTOS PETROQUIMICOS S.A. de
C.V.
km. 112.8 Carretera México-Puebla-Tehuacán, Puebla, Puebla 72000
Company address:
Telephone Numbers
Transportation Emergency
Company:
SETIQ (México)
CHEMTREC (USA):
CANUTEC (Canada)
Medical Emergency:
General MSDS Assistance :
Technical Information:
+ (52) (222) 282-6200
01-800-00-214-00
800-424-930
(613) 996-66660
+ (52) (222) 282-6200
+ (52) (222) 282-6200
+ (52) (222) 282-6200
2.
HAZARD IDENTIFICATION
2.1 Classification of the substance or mixture: In accordance with 67/548/ECC Regulation
Xn; R22
Xi; R37/38-41
R22: Harmful if swallowed.
R34: Causes burns.
R42/43: May cause sensitization by inhalation and skin contact.
In accordance with 1272/2008 Regulation
Acute Tox (oral). 4; H302
Skin Corr. 1B; H314
Skin Sens. 1; H317
Resp. Sens. 1; H334
2.2 Label elements
Pictogram
Signal
word
Danger
Hazard
statements
H302
H314
H317
H334
Precautionary statements
P260
P261
P264
P270
P272
P280
P285
2.3 Other hazards: Transport temperature: >65ºC. Danger of burning due to the high temperature.
Fumes are irritating to skin, eyes and mucous membranes.
* For the full meaning of the phrases R and / or hazard (H): see section 16
P301 + P-330
+P331
P303 + P361 +
P353
P304 + P340
P305 + P351 +
P338
P332 + P313
P363
P-501
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
3. COMPOSITION AND INFORMATION ON INGREDIENTS
3.1 Substances
Name
EC N°
CAS N°
IUPAC name
Maleic
Anhydride
203-571-6
108-31-6
Maleic Anhydride
Index
number
607-096-00-0
%
(w/w)
99
Exposure Limits
1 mg/ m3 TWAACGIH
4. FIRST AID MEASURES
4.1
General
Inhalation
Ingestion
Skin
Eye
4.2
Most important symptoms and effects, both acute and delayed.
Ingestion
Inhalation
Eye contact
Skin contact
4.3
Remove contaminated clothing.
Remove victim to fresh air. If breathing is difficult give medical oxygen. Get medical attention
immediately.
Never give anything by mouth if victim is rapidly losing consciousness, is unconscious or
convulsing. DO NOT INDUCE VOMITING. Have victim drink two glasses of water to dilute
material in the stomach. If milk is available, it may be administrated AFTER the water has been
given. If vomiting occurs naturally, have the victim lean forward to reduce risk of aspiration, rinse
mouth and repeat administration of water. Get medical attention immediately.
Immediately flush contaminated area with lukewarm, gently running water for at least 20-30
minutes. Under running water, remove contaminated clothing, shoes and leather goods. Get
medical attention immediately.
Immediately flush the contaminated eye(s) with lukewarm, gently flowing water for at least 20-30
minutes, while holding the eyelid(s) open. Get medical attention immediately.
Medical
attention
Toxic by ingestion; can cause severe irritation of the mouth, throat, and digestive tract based in its
corrosives. Ingestion is not a typical route of occupational exposure.
Vapors, fumes or dust can cause severe irritation of the nose, throat, and respiratory tract.
Symptoms of exposure may include coughing, sneezing, shortness of breath, nosebleeds and
vomiting, depending on severity of exposure. High concentrations may cause a life-threatening
accumulation of fluid in the lungs. Prolonged or repeated inhalation may cause chronic bronchitis.
Dust or concentrated solutions may cause severe irritation or corrosive injury. Vapors can
produce redness, irritation blurred vision and burning sensation. Severe eye damage may result
in blindness.
On moist skin, maleic anhydride forms maleic acid and can cause severe irritation or burns. It
may be absorbed through the skin, but is not likely to cause toxic effects. Prolonged skin contact
may cause dermatitis
Treat according to symptoms (decontamination, vital functions), no known specific antidote.
5. FIRE – FIGHTING MEASURES
5.1
Suitable extinguish media
Use water spray or fog, alcohol foam, polymer foam, carbon dioxide.
5.2
Unsuitable extinguish
media
Special hazards
DO NOT USE dry chemical powder, these extinguishers contain sodium or
potassium carbonates which react violently with Maleic anhydride.
Maleic Anhydride can burn if strongly heated. During fire, irritating/toxic gases and
fumes may be generated. Can form explosive dust or moisture..
Burning may produce carbon monoxide, carbon dioxide, and acetylene; acid fumes
and other toxic materials. Incomplete combustion may also produce acrid smoke and
irritating fumes.
Water spray or fog carefully applied to surface of the burning material can be used to
extinguish the fire. Use water spray to prevent dust formation, absorb heat, keep
containers cool and protect fire-exposed materials. Do not get water into Maleic
Anhydride containers. Use water spray to flush spills away from ignition sources.
Wear full protective clothing (chemical splash suit) and positive pressure selfcontained breathing apparatus.
Combustion decomposition
products
5.3
Advice for firefighters
Personal protective
equipment
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
1
NATIONAL FIRE PROTECTION ASSOCIATION (NFPA) HAZARD IDENTIFICATION
NFPA - Health:
3 - Short exposure could cause serious temporary or residual injury.
NFPA - Flammability:
1 - Must be preheated before ignition can occur.
NFPA - Instability:
1 - Normally stable, but can become unstable at elevated temperatures and pressures.
3
6. ACCIDENTAL RELEASE MEASURES
6.1
Personal precautions
Ventilate and evacuate area of spill or leak. Remove all ignition sources (heat, sparks,
flames, etc.). Use appropriate personal protective equipment. Including full-face respirator
6.2
Environmental precautions
Stop or reduce leak if possible and safe.
6.3
Methods and material for
containment and cleaning
up
6.4
Reference to other
sections
Molten Maleic anhydride: Building barriers with earth, sand or absorbent material which
does not react with the material spilled and collected in suitable containers to prevent that
this product reaches drains or sewers. It is advisable to expect to solidify.
Solid Maleic anhydride: Collect material into suitable containers for disposal.
Use water to rinse the affected area and carbonate to neutralize it.
Shovel material into suitable, covered, labeled containers. Flush area with water.
Contaminated absorbent material may pose the same hazards as the spilled material.
See section 8 to personal protective protection and section 13 to waste treatment methods
Remark: see section 8 to personal protective protection and section 13 to waste treatment methods
7. HANDLING AND STORAGE
7.1
Precautions for safe
handling
This material is a CORROSIVE, INHALATION HAZARD, RESPIRATORY SENSITIZER, EYE
IRRITANT, SKIN SENSITIZER molten liquid. As the material is handled at 60 ºC or hotter there
is the additional risk of THERMAL BURNS. Before handling, it is extremely important that
engineering controls are operating and that protective equipment requirement and personal
hygiene measures are being followed. People working with this chemical should be properly
trained regarding its hazards and its safe use.
Only authorized personnel should have access to this material. They should be properly trained
regarding its hazards and its safe use. Maintenance and emergency personnel should be
advised of potential hazards.
If molten maleic anhydride is released, immediately put on a suitable respirator and leave the
area until the severity of the release is determined. In case of leaks or spills, escape-type
respiratory protective equipment should be available in the work area.
Immediately report leaks, spills or failures of the engineering controls. Unprotected persons
should avoid all contact with this chemical including contaminated equipment. Be aware of
typical signs and symptoms of poisoning and first aid procedures. Any signs of illness should be
reported immediately to supervisory personnel. Seek medical attention for all exposures, even if
the exposure did not seem significant. Symptoms can be delayed.
Use in clearly posted, designated area(s). Control access to designated area. Access doors
must remain closed while this material is present.
Closed handling systems for processes involving this material should be used. If this is not
possible, use this material in the smallest possible amounts in appropriate labeled, containment
devices (e.g. fume hood). Prevent the release of vapors into the workplace air. Containment
devices should be made of smooth, unbreakable, compatible material. Maintain containment
devices at appropriate air flow and negative pressure. Check regularly.
Cover work surfaces with compatible, impervious and/or disposable material for easier
containment and clean-up of spills. Keeping work areas clean is essential. Use work surfaces
that can be easily decontaminated.
Protect from accidental contact with water. Do not use with other incompatible materials such
as oxidizing agents and bases. See Incompatibilities - Materials to Avoid section for more
information.
Do not perform any welding, cutting, soldering, drilling or other hot work on empty containers or
transfer equipment until all this material has been removed
1
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
7.2
Conditions for safe
storage, including
any
incompatibilities
Store in a cool, dry, well-ventilated area out of direct sunlight and away from heat and ignition
sources. Avoid bulk storage indoors. Storage area should be clearly identified, clear of
obstruction and accessible only to trained and authorized personnel. Keep storage area
separate from work areas. Protect form accidental contact with water. Post warning signs. Have
appropriate fire extinguishers and spill clean-up equipment in or near storage area. Storage
facilities should be made of fire resistant materials. Storage away from oxidizers and other
incompatible materials such as bases. Keep containers tightly closed and labeled.
7.3
Specific end use(s)
See section 1.2
Remark: stability and reactivity, see Section 10
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1
Exposure limits
DNEL
PNEC
8.2
oral
inhalation
dermal
water
Not
available
industrial
Not available
Not available
Not available
air
soil
Not
Not
availa
available
ble
consumer
Not available
Not available
Not available
microbiological
Not available
sediment
oral
Not
available
Not
available
Exposure controls
Hygienic controls
Individual
protection
Eyes
Skin and
body
Respiratory
Use chemical safety goggles and/or a full face shield where splashing is
possible.
Wear chemical protective gloves, coveralls and boots. Have a safety shower and
eye-wash fountain readily available in the immediate work area.
Up to 10 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode.
(APF = 50) Any self-contained breathing apparatus with a full face piece. Any
supplied-air respirator with a full face piece.
Emergency or planned entry into unknown concentrations or IDLH conditions
(APF = 10,000) Any self-contained breathing apparatus that has a full face piece
and is operated in a pressure-demand or other positive-pressure mode. Any
supplied-air respirator that has a full face piece and is operated in a pressuredemand or other positive-pressure mode in combination with an auxiliary selfcontained positive-pressure breathing apparatus
Environmental exposure controls
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance:
Colour:
Odors:
Molecular Weight:
pH:
Melting Point:
Boiling Point:
Flash Point:
Flammability:
Explosive properties:
Autoignition (Ignition) Temperature:
Decomposition Temperature:
Lower Flammable (Explosive)
Limit (LFL/LEL):
Upper Flammable (Explosive)
Limit (UFL/UEL):
Oxidizing properties:
Relative Density :
Vapors Pressure:
Vapors Density:
Liquid molten / Solid at room temperature.
White.
Acrid, choking odor.
98.06
2.42 (0.01m solution)
52.4 ºC ( 126.4 ºF)
202 ºC (395.6 ºF)
103 ºC ( 217ºC) (closed cup)
Not available.
Non explosive.
475 to 480 ºC (887 to 896 ºF)
Not available.
1.4 % (v/v)
7.1 % (v/v)
Not available.
1.32 ( 65 ºC)
2.8 hPa (52.9 ºC)
3.38 (air = 1)
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
Partition coefficient: n-octanol/water:
Viscosity -Dynamic:
9.2 Additional information:
Solubility in Other Liquids:
Not available
1.61 mPa´s (1.61 cP)
Very soluble in acetone and ethyl acetate; soluble in benzene,
chloroform, diethyl ether, toluene, o-xylene and dioxane; slightly
soluble in carbon tetrachloride and kerosene.
10. STABILITY AND REACTIVITY
10.1
10.2
10.3
10.4
Reactivity
Chemical stability
Possibility of hazardous
reactions
Conditions to avoid
10.5
Incompatible materials
10.6
Hazardous decomposition
products
Hazardous Polymerization
10.7
Stable under normal conditions
Not available
Does not occur
Alkaline hydroxide, Alkali metals, Sodium hydroxide, Potassium hydroxide, Static
charge, sparks, heat , other ignition sources, generation of dust and moisture.
Reacts with water and forms maleic acid. With strong oxidizing agents
(perchlorates, peroxides, chromates) and strong reducing agents (phosphorus,
chloride) may react violently. Avoid alkali metals, alkalis, alkaline earth metals,
alkaline earth hydroxides, amines, pyridine, quinoline, sodium or potassium
carbonates, aqueous ammonia, or ammonium salts
In the case de fire or at high temperatures the formation of the following
decomposition products possible irritant gases / vapors.
Does not occur
11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
Constituent
CAS Nº
Method
Not
available
Maleic
anhydride
108-31-6
Skin corrosion/irritation
Constituent
CAS Nº
Species
Rat
Mouse
Rabbit
Via
Oral
Oral
Oral
Rat
Inhalation
Rabbit
Dermal
Result
LD 50 = 1090 mg / Kg bw
LD 50 = 465 mg / Kg bw
LD 50 = 875 mg / Kg bw
.
LC50 > 210 mg/l air. Based on available data, the
classification criteria are not met
LD 50 = 2620 mg/kg bw. Based on available data, the
classification criteria are not met
Method
Draize test
OECD 404
Species
Rabbit
Rabbit
Via
skin
skin
Result
Slightly irritating.
Slightly irritating.
Classified as skin irritating
Serious eye damage/irritation
Constituent
CAS Nº
Method
Draize test
Maleic
108-31-6
anhydride
Species
Rabbit
Via
Eye
Result
Causes severe damage to the eyes with redness, pain,
photophobia, conjuntivitis and blurred vision
Species
Guinea
pig
human
Guinea
pig
Via
Intracutaneo
us
skin and
inhalation
inhalation
Maleic
anhydride
108-31-6
Respiratory or skin sensitization
Constituent
CAS Nº
Method
Intracutaneo
us test
Maleic
108-31-6
anhydride
Result
Sensitizing.
Sensitizing (asthma, rhinitis, dermatitis)
Sensitizing
Classified as skin and respiratory sensitizing
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
Carcinogenicity
Constituent
CAS Nº
Maleic
anhydride
Method
Not available
Species
Rat
mouse
Via
Oral
oral
Result
No carcinogenic effect.
Not carcinogenic effect.
Based on available data, the classification
criteria are not met
108-31-6
Not listed as carcinogenic to humans (IARC).
Germ cell mutagenicity
Constituent
CAS Nº
Maleic
anhydride
108-31-6
Reproductive toxicity
Constituent
CAS Nº
Maleic
108-31-6
anhydride
STOT-single exposure
Constituent
CAS Nº
Maleic
anhydride
Method
Ames test
Chromosome
aberrations test
Chromosome
aberration test
Species
Salmonella
typhimorium
Chinese Hamster
Ovary (CHO) cells
Mamallian cells
Via
Result
Not mutagenic
Negative
Negative
Based on available data, the
classification criteria are not met
Method
Species
Via
Result
Not available. Data lacking
Method
Species
human
Via
Result
Maleic anhydride in the form of vapor, fume or
dust is a primary irritant to mucous membranes an
the upper respiratory tract.
108-31-6
Classified as specific target organ toxic - single
exposure, respiratory.
STOT-repeated exposure
Constituent
CAS Nº
Maleic
anhydride
108-31-6
Aspiration hazard
Constituent
CAS Nº
Maleic
108-31-6
anhydride
Method
Period 8
months,
treatment 3
hours/day on 4
following days
an 10 days
break, doses
0.0085 mg/l
Species
Guinea
pig
Method
Species
Via
inhalation
Result
Irritation of the conjunctiva and mucosa of the
lung, death and loss of superficial mucosal cells,
alveolary hyperemia.
Based on available data, the classification criteria
are not met
Via
Result
Not available. Data lacking
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
12. ECOLOGICAL INFORMATION
12.1 Toxicity
Aquatic toxicity
Constituent
CAS Nº
Fish
LC 50 (96h) = 230
mg/l
Not available
Short term
Maleic anhydride
108-31-6
Long term
Aquatic invertebrates
Not available
Algae
Not available
Not available
Microbiological activity in sewage treatment plant
Componente
CAS Nº
Toxicity to aquatic microorganisms
Maleic anhydride
Earth toxicity
Constituent
Maleic anhydride
108-31-6
LOEC (48h) = 1 mg/l
EC50 (3 h) > 1000 mg/l
CAS Nº
108-31-6
Microorganisms
Not available
Microorganisms
Not available
12.2 Persistence and degradability
Constituent
CAS Nº
Degradation half
lives
Period
Maleic anhydride
108-31-6
12.3 Bioaccumulative potential
Constituent
CAS Nº
Maleic anhydride
108-31-6
12.4 Mobility in soil
Constituent
CAS Nº
Maleic anhydride
108-31-6
Hydrolysis
Not available
Photolysis
Not available
Biodegradation
Not available
Partition coefficient: noctanol/water
Not available
Other organisms
Not available
Potential to degrade
in sewage treatment
plant
Not available
Not available
Bioconcentration factor
(BCF)
Not available
Comments
Result
Moderate
mobility.
12.5 Results of PBT and vPvB assessment :
12.6 Other adverse affects.
PBT and vPvB assessment have not been developed.
Not available
13. DISPOSAL CONSIDERATION
13.1 Waste treatment methods
Review federal, provincial and local government requirements prior to disposal.
14. TRANSPORT INFORMATION
14.1 Regulatory
information
UN number
Class ADR/RID
2215
Class ADNR
2215
Class IMDG
2215
UN proper
shipping
name
MALEIC
ANHYDRIDE,
MOLTEN
MALEIC
ANHYDRIDE,
MOLTEN
MALEIC
ANHYDRIDE,
MOLTEN
Transport
hazard class
Packing
group
Environmental
hazards
Special
precautions
for user
8
III
Not available
Not available
8
III
Not available
Not available
Not available
Emergency
schedules
(EmS) F-A, SB
8
III
MSDS NAME: MALEIC ANHYDRIDE
DATE PRINTED: APRIL 06, 2015
COMPANY:
RETER CPP
Class ICAO and
IATA -DGR
MALEIC
ANHYDRIDE,
8
III
Not available
MOLTEN
14.2 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code: not available
2215
Not available
15. REGULATORY INFORMATION
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture.
16. OTHER INFORMATION
Risk Phrases
R22: Harmful if swallowed.
R34: Causes burns
R37/38: Irritating to respiratory system and skin.
R41: Risk of serious damage to eyes.
R42/43: May cause sensitization by inhalation and skin contact.
H302: Harmful if swallowed.
H314: Causes severe skin burns and eye damage.
H317: May cause an allergic skin reaction.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Hazard statements
Precautionary statements
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P272: Contaminated work clothing should not be allowed out of the
workplace.
P280: Wear protective gloves/protective clothing/eye protection/face
protection.
P285: In case of inadequate ventilation wear respiratory protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all
contaminated clothing. Rinse skin with water/shower.
P304+P340. IF INHALED: Remove victim to fresh air and keep at rest in a position
comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313 If skin irritation occurs: Get medical advice/ attention.
P363 Wash contaminated clothing before reuse
P501: Dispose of contents/container in accordance to local legislation
THIS INFORMATION IS BASED UPON CALCULATED DATA. THE COMPANY HOLDS NO RESPONSIBILITY FOR
DAMAGE SUFFERED BY THE PURCHASER OR OTHER PERSONS HANDLING THESE GOODS IF SAFETY
INSTRUCTIONS ARE NOT OBSERVED. THE COMPANY HOLDS NO RESPONSIBILITY FOR THE WRONG USE OF THIS
MATERIAL, EVEN IF SAFETY INSTRUCTIONS HAVE BEEN FOLLOWED.
THE PURCHASER IS SOLELY
RESPONSIBLE FOR THE USE OF THIS MATERIAL.
MSDS Creation Date: 4/02/ 2002 Revision #4 Date: April 06, 2015 -AZA