IBM PROGRAM FACULTY CANCER AND STEM CELL BIOLOGY Prof. David M. VIRSHUP  Tel: (+65) 6516 7881  Email: david.virshup@duke‐nus.edu.sg Prof. Patrick J CASEY  Tel: (+65) 6516 7251  Email: casey006@mc.duke.edu Asst. Prof. Mathijs VOORHOEVE  Tel: (+65) 6516 2503  Email: mathijs.voorhoeve@duke‐nus.edu.sg Asst. Prof. Alexandra PIETERSEN  Tel: (+65) 6223 7241  Email: alexandra.pietersen@duke‐nus.edu.sg Asst. Prof. Koji ITAHANA  Tel: (+65) 6516 2554  Email: koji.itahana@duke‐nus.edu.sg  Cancer Biology, Signal Transduction, protein phosphorylation, Wnt signaling  Cancer Biology, G protein, signal transduction, metastasis
 Cancer Biology, tumor suppressors and oncogenes, microRNA, non‐
coding RNAs  Mammary stem cells and breast cancer, mouse models, flow cytometry  ARF‐Mdm2‐p53 tumor suppressor pathway, apoptosis, cancer metabolism IBM PROGRAM FACULTY CANCER AND STEM CELL BIOLOGY Assoc. Prof. ONG Sin Tiong  Tel: (+65) 6516 7763  Email: sintiong.ong@duke‐nus.edu.sg Assoc. Prof. Patrick TAN Boon Ooi  Tel: (+65) 6516 1783  Email: gmstanp@duke‐nus.edu.sg Assoc. Prof. Caroline LEE Guat Lay  Tel: (+65) 6516 3251/(+65) 6436 8353  Email: caroline.lee@duke‐nus.edu.sg Asst. Prof. Mei WANG  Tel: (+65) 6516 8608  Email: mei.wang@duke‐nus.edu.sg Asst. Prof. LI Shang  Tel: (+65) 6601 1259  Email: shang.li@duke‐nus.edu.sg  Therapeutic targeting of cancer stem cells, mechanisms of drug resistance, haematologic malignancies  Stomach cancer, cancer genomics, translational medicine  Functional Genomics of Hepatocellular
Carcinoma, Pharmaco‐genetics/ genomics, Population Genetics, Polymorphisms  Cancer Biology, oncogenes, protein prenylation, cancer therapeutics, cell death pathways  Telomerase regulation, cancer and aging IBM PROGRAM FACULTY CANCER AND STEM CELL BIOLOGY  Regulation of cell fate by the proto‐
oncogene, c‐Jun and associated JNK signaling pathway; (ii) Role and regulation of p53 and p73 activity; (iii) Mouse models for cancer: “Knock‐in” mice for the study of p53 hotspot mutations and p73 in vivo; (iv) Genetic screens for cancer therapeutic agents Assoc. Prof. Kanaga SABAPATHY  Tel: (+65) 6436 8349  Email: cmrksb@nccs.com.sg  Cell death and survival signaling. Redox regulation of cell fate, Bcl‐2 family and mitochondrial physiology, experimental therapeutics, novel drug discovery Prof. Shazib PERVAIZ  Tel: (+65) 6516 6602  Email: Shazib_Pervaiz@nuhs.edu.sg  Cancer Biology, Mitotic checkpoint, chromosomal instability, aneuploidy, anti‐mitotic therapy Asst. Prof LEE Sang Hyun  Tel: (+65) 6601 1406  Email: sanghyun.lee@duke‐nus.edu.sg
IBM PROGRAM FACULTY CARDIOVASCULAR & METABOLIC DISORDERS Assoc. Prof. Scott A. SUMMERS  Lipid metabolism; diabetes
 Tel: (+65) 6516 8793  Email: scott.summers@duke‐nus.edu.sg Assoc. Prof Paul M. YEN  Tel: (+65) 6516 7332  Email: Paul.yen@duke‐nus.edu.sg  Thyroid function; nuclear hormone receptors; PI3‐kinase and cancer Prof. Shirish SHENOLIKAR  Tel: (+65) 6223 7241  Email: Shirish.shenolikar@duke‐nus.edu.sg  Protein phosphatases; transduction of signals by metabolic and environmental stress Dr Shigeki SUGII  Tel: (+65) 6478 8763  Email: shigekisugii@gmail.com  Adipose stem cells; iPS cells; fat metabolism; diabetes; nuclear hormone receptors; human disease modeling; regenerative therapeutics IBM PROGRAM FACULTY HEALTH SERVICES & SYSTEMS RESEARCH Prof. David MATCHAR  Tel: (+65) 6516 2584  Email: david.matchar@duke‐nus.edu.sg Assoc. Prof. Eric FINKELSTEIN  Tel: (+65) 6516 2338  Email: eric.finkelstein@duke‐nus.edu.sg Assoc. Prof. Angelique CHAN  Clinical health policy, health systems modeling, practice organization/improvement,  Economic evaluation, obesity, incentives  Aging, care giving, mental health
 Tel: (+65) 6223 5027  Email: socchana@nus.edu.sg Dr Young DO  Tel: (+65) 6516 2790  Email: young.do@duke‐nus.edu.sg  Health services and systems research, health economics, aging and long‐term care, noncommunicable diseases and major risk factors, health system and policy, program evaluation, econometric methods, southeast Asia, east Asia IBM PROGRAM FACULTY EMERGING INFECTIOUS DISEASES Prof. Duane J. GUBLER  Tel: (+65) 6516 7256  Email: duane.gubler@duke‐nus.edu.sg Assoc. Prof. OOI Eng Eong  Tel: (+65) 6516 8594  Email: engeong.ooi@duke‐nus.edu.sg Asst. Prof. LOK Sheemei  Tel: (+65) 6516 5840  Email: sheemei.lok@duke‐nus.edu.sg Asst. Prof. Manoj KRISHNAN  Tel: (+65) 6516 2666  Email: Manoj.krishnan@duke‐nus.edu.sg  Zoonotic and vector‐borne diseases, epidemiology, ecology, prevention and control  Clinical epidemiology and pathogenesis of dengue, etiology of acute viral syndromes
 Antibody neutralization mechanism of dengue virus, immunological, molecular and structural techniques  Cellular infection mechanisms of alphaviruses focusing on chikungunya virus; innate immune mechanisms thwarting RNA virus infection, antiviral host targets and antivirals IBM PROGRAM FACULTY EMERGING INFECTIOUS DISEASES Prof. Gavin SMITH  Tel: (+65) 6601 1109  Email: Gavin.smith@duke‐nus.edu.sg Assoc. Prof. Veronika Von MESSLING  Tel: (+65) 6601 1372  Email: veronika.vonmessling@duke‐nus.edu.sg Assoc. Prof. Subhash VASUDEVAN  Tel: (+65) 6516 6718  Email: subhash.vasudevan@duke‐nus.edu.sg  Ecology, evolution, population dynamics, molecular epidemiology, interspecies transmission of emerging infectious diseases
 Characterization of respiratory viruses pathogenesis  Antiviral therapeutics for flaviviruses; flaviviral proteases, protein‐protein and protein‐RNA interactions of flaviviral replication complex, structure and function studies of multifunctional viral proteins IBM PROGRAM FACULTY NEUROSCIENCE & BEHAVIORAL DISORDERS Prof. Dale PURVES  Tel: (+65) 6516 4386  Email: purves@neuro.duke.edu Prof. George J. AUGUSTINE  Tel: (+65) 6586 9542  Email: georgea@neuro.duke.edu Prof. Michael CHEE  Tel: (+65) 6516 4916  Email: michael.chee@duke‐nus.edu.sg Asst. Prof. Marc FIVAZ  Tel: (+65) 6516 7748  Email: marc.fivaz@duke‐nus.edu.sg  Visual and auditory perception
 Function of synaptic connections between nerve cells. Mechanisms of neurotransmitter release. Pathways underlying long‐lasting synaptic plasticity  Cognitive neuroscience. Understanding changes in attention, decision making and affect in the setting of sleep deprivation and using functional and structural brain imaging in translational medicine settings  Neuronal morphogenesis and plasticity IBM PROGRAM FACULTY NEUROSCIENCE & BEHAVIORAL DISORDERS  CNS neuronal regeneration. Biology of neural stem cells Asst. Prof. Eyleen GOH  Tel: (+65) 6516 6701  Email: eyleen.goh@duke‐nus.edu.sg Asst. Prof. Joshua J. GOOLEY  Neural pathways underlying synchronization of the human circadian timing system. Interaction between sleep and circadian rhythms  Tel: (+65) 6516 7430  Email: joshua.gooley@duke‐nus.edu.sg Prof. Ranga KRISHNAN  Affective disorders, anxiety disorders, obsessive‐compulsive disorders, psychopharmacology, geriatric depression  Tel: (+65) 6516 7666  Email: ranga.krishnan@duke‐nus.edu.sg Assoc. Prof. LEE Tih‐Shih  Tel: (+65) 6516 7461  Email: tihshih.lee@duke‐nus.edu.sg  Molecular basis of temporal lobe epilepsy, dementia and other neuropsychiatric disorders; brain‐
computer interface treatment of attention deficit and hyperactivity disorder IBM PROGRAM FACULTY NEUROSCIENCE & BEHAVIORAL DISORDERS Assoc. Prof. LIM Kah Leong  Tel: (+65) 6357 7520  Email: kahleong.lim@duke‐nus.edu.sg Assoc. Prof. Steve ROZEN  Tel: (+65) 6516 4945/(+65) 6516 5920  Email: steve.rozen@duke‐nus.edu.sg Prof. Shirish SHENOLIKAR  Tel: (+65) 62230 7241  Email: Shirish.shenolikar@duke‐nus.edu.sg Assoc. Prof. TAN Eng King  Tel: (+65) 6326 5003  Email: gnrtek@sgh.com.sg Assoc. Prof. Antonius VANDONGEN  Tel: (+65) 6516 7075  Email: antonius.vandongen@duke‐nus.edu.sg  Molecular mechanisms of neurodegeneration in Parkinson’s disease
 Genome‐scale biology, bioinformatics, and human genetics  Role of protein phosphatases in neurological diseases  Cinical and translational research in Parkinson’s Disease, essential tremor, Alzheimer’s disease, spinocerebellar ataxias, restless legs syndrome and related neurodegenerative disorders  Biology of NMDA receptor and its role in learning and memory IBM PROGRAM FACULTY NEUROSCIENCE & BEHAVIORAL DISORDERS Asst. Prof. WANG Hongyan  Tel: (+65) 6516 7740  Email: hongyan.wang@duke‐nus.edu.sg Asst. Prof. ZHANG Xiaodong  Tel: (+65) 6516 8809  Email: xiaodong.zhang@duke‐nus.edu.sg Assoc. Prof. Suresh Jeyaraj JESUTHASAN  Tel: (+65) 6407 0390  Email: Suresh.Jesuthasan@nrp.a‐star.edu.sg Dr Hyunsoo Shawn JE  Tel: (+65) 6601 1260  Email: Shawn.je@duke‐nus.edu.sg  Mechanisms underlying neural stem cell self‐renewal and differentiation  Functional characterization of tryptophan hydroxylase gene and its role in neuropsychiatric disorders  Emotion, fear, anxiety, pheromone, olfactory, optical recording, optogenetic, learning, operant conditioning, network  Developing a circuit‐based mouse model of schizophrenia and autism. synaptic plasticity, schizophrenia, brain‐derived neurotrophic factor (BDNF), autism, interneuron, dendritic spine, electrophysiology, multiphoton microscopy IBM PROGRAM FACULTY NEUROSCIENCE & BEHAVIORAL DISORDERS Asst. Prof. Po‐Jang (Brown) HSIEH  Tel: (+65) 6601 2088  Email: pojang.hsieh@duke‐nus.edu.sg  Human cognition, attention, visual awareness, object perception and recognition, decision making, human brain mapping with fMRI and diffusion imaging