Student Handbook 2015-2016 Biomedical Sciences/Human Biology 1 INDEX Page Message from the Acting Director 3 Module Coordinator Contact Information 5 Semester Dates 7 Student Support and Welfare 8 Your Responsibilities 9 General Regulations and Research Mentoring Programme 11 Biomedical Sciences Programme Information 12 Institute of Biomedical Science Accreditation Information 20 Human Biology Programme Information 22 Indicative Timetables 29 Module Descriptors 32 University Information 65-67 2 Dear Student, Welcome to Queens and in particular to that part of it where you will be based, the Centre for Biomedical Sciences Education. You have joined an academic fraternity of people who have a deep interest in the biomedical sciences and their application in understanding and treating disease. You may be at the junior end of this fraternity, but with diligent study, you will gain knowledge and skills each year as we seek to optimise your potential, towards employment or further study. You are privileged to live at a time when the potential offered by the Human Genome Project is being realised, providing powerful research tools that will open the door for effective treatments of diseases, previously considered incurable. Our mission is to oversee and guide you through this part of your academic life. We provide outstanding facilities, staffed by award winning teachers and world class researchers. Use that expertise and become the best you can be. Good luck with your studies. Dr Stephen McCullough Acting Director 3 CONTACT DETAILS AND LOCATION Address: Centre for Biomedical Sciences Education Queen’s University Belfast Whitla Medical Building (First Floor) 97 Lisburn Road Belfast BT9 7AE Centre General Office Telephone: Fax Email: 028 9097 2677/2130/2043 028 9097 2124 biomedsci@qub.ac.uk Centre Office will be open from 8.45am to 5.00pm, Monday to Friday. Acting Director Acting Deputy Director Centre Manager Dr Stephen McCullough Dr Aisling Keane Ms Bronagh Shannon s.j.mccullough@qub.ac.uk a.keane@qub.ac.uk b.shannon@qub.ac.uk 4 MODULE CO-ORDINATORS – CONTACT INFORMATION Level 1 Modules Module Code Module Title BMS1001 Human Structure and Function: Principles BMS1002 Human Structure and Function: Systematic Body Systems Introductory Skills for Biosciences Module Coordinator(s) Dr A Al-Modhefer Email Address a.al-modhefer@qub.ac.uk e.tansey@qub.ac.uk a.keane@qub.ac.uk t.caruso@qub.ac.uk j.dalzell@qub.ac.uk GEN1005 Dr E Tansey Dr A Keane Dr T Caruso / Dr Johnathan Dalzell Genetics and Molecular Biology Dr Mark Robinson BCH1002 Biochemistry Dr C Allen c.allen@qub.ac.uk MCB1006 Microorganisms Dr L Stewart l.stewart@qub.ac.uk Module Code Module Title Email Address ALU2008 Diet and health Module Coordinator(s) Dr G Cuskelly BBC2012 Molecular Genetics BMS2001 Topographical Anatomy 1 Dr K Panov/Dr E Hoey/Dr John Quinn Dr D Shanahan k.panov@qub.ac.uk e.hoey@qub.ac.uk j.quinn@qub.ac.uk d.shanahan@qub.ac.uk BMS2007 BMS2015 Cardiovascular and Respiratory Dr E Tansey Physiology Exercise and Applied Dr S Roe Physiology Scientific Methods and Statistics Dr T Gardiner Dr C Cardwell Molecular Cell Biology Dr W Allen BMS2016 Immunobiology Dr A Kissenpfennig a.kissenpfennig@qub.ac.uk BMS2017 Biomedical Science in Practice Dr E Donnelly e.donnelly@qub.ac.uk BMS2023 Pathobiology Prof K Mills k.mills@qub.ac.uk BMS2026 Cells and Tissues Dr C Foy / Dr J Quinn c.foy@qub.ac.uk joe.quinn@qub.ac.uk BMS2027 Drugs and the Human Body Dr Laura Montgomery l.e.a.montgomery@qub.ac.uk BMS2028 Human Physiological Measurement Dr C Johnson c.johnson@qub.ac.uk BSC1009 mark.robinson@qub.ac.uk Level 2 Modules BMS2008 BMS2014 g.cuskelly@qub.ac.uk e.tansey@qub.ac.uk s.roe@qub.ac.uk t.gardiner@qub.ac.uk c.cardwell@qub.ac.uk w.allen@qub.ac.uk 5 Level 3 Modules Module Code Module Title Email Address Neuroscience Module Coordinator(s) Dr A Al-Modhefer BMS3002 BMS3003 Developmental Studies Dr W Allen w.allen@qub.ac.uk BMS3005 Advanced Cardiovascular Physiology Cellular and Molecular Haematology Topographical Anatomy 2 Dr T Curtis t.curtis@qub.ac.uk Prof K Mills k.mills@qub.ac.uk BMS3009 BMS3011 a.al-modhefer@qub.ac.uk d.shanahan@qub.ac.uk BMS3015 Dr Donal Shanahan Research Project – process and Dr W Allen thesis Scientific Literature Review Dr W Allen BMS3024 Tissue Biology and Pathology Dr E Donnelly e.donnelly@qub.ac.uk BMS3025 Clinical Biochemistry Dr A McGinty a.mcginty@qub.ac.uk BMS3027 Vascular Biology Dr D McDonald d.mcdonald@qub.ac.uk TPU3001 Molecular Pharmacology Dr D Bell d.bell@qub.ac.uk TPU3006 Cardiovascular Pharmacology Dr D Bell d.bell@qub.ac.uk TPU3008 Integrated Pharmacology Dr D Bell d.bell@qub.ac.uk EDU3009 Science in Education SCM3001 Clinical Nutrition Dr W McClune/Dr R Jarman Dr M McKinley w.mcclune@qub.ac.uk; r.jarman@qub.ac.uk m.mckinley@qub.ac.uk VMI3005 Infections To be confirmed BMS3012 w.allen@qub.ac.uk w.allen@qub.ac.uk 6 SEMESTER DATES 2015/16 Autumn Semester Welcome week, Monday 21 September - Friday 25 September 2015 registration and enrolment Teaching Monday 28 September – Friday 18 December 2015 (Weeks 1-12) Vacation Monday 21 December 2014 – Friday 8 January 2016 Assessment Monday 11 January – Tuesday 26 January 2016 (Weeks 13-15) Vacation Wednesday 27 January – Friday 29 January 2016 Deadline for return of Tuesday 09 February 2016 examination results Spring Semester Teaching Monday 1 February – Friday 18 March 2016 (Weeks 1-7) Vacation Monday 21 March – Friday 08 April 2016 Teaching Monday 11 April – Friday 13 May 2016 (Weeks 8-12) Revision Monday 16 May – Wednesday 18 May 2016 Assessment Thursday 19 May – Saturday 4 June 2016 (Weeks 13-15) Deadline for return of Monday 20 June 2016 examination results Rag Day: 17 February 2016 Reading Day: 16 and 18 March 2016 Good Friday: 25 March 2016 Graduation week: 30 June – 6th July 2016 August re-sit examinations: Monday 08 August – Saturday 20 August 2016 Deadline for return of examination results: Tuesday 30 August 2016 University Semester dates for academic year 2015-16 can be found at http://www.qub.ac.uk/directorates/AcademicAffairs/SemesterDates/ 7 STUDENT SUPPORT AND WELFARE There may be times when you feel that you need help, support and/or advice for academic or personal problems. Although any member of Academic Staff will be willing to help, several have specific areas of responsibility and these are listed below. Also, further advice for Student Development and Support can be found at www.qub.ac.uk/studentinfo Advisers of Studies Your Adviser of Studies will provide advice on enrolment at the commencement of each academic year. They will monitor your progress throughout the course and may request to see you if your academic progress or attendance is causing concern. Advisers will also provide advice and assist you to interpret the University and pathway regulations. You will need to seek their permission in order to transfer to another pathway or to change the modules you have enrolled for (within the first two weeks of the Semester only). Advisers are available to discuss any problems (e.g. personal or financial) which you feel may be impacting adversely on your academic progress or attendance. You will have been notified of your Adviser of Studies at enrolment. Advisers for 2015/16 for students on the Biomedical Science and Human Biology pathways are as follows: Ms Samantha Taylor (Level 1) First Floor, Whitla Medical Building Tel: 028 9097 2143 email: s.j.taylor@qub.ac.uk Dr Etain Tansey (Level 2) First Floor, Whitla Medical Building Tel: 028 9097 2315 email: e.tansey@qub.ac.uk Dr Christopher Johnson (Level 3) First Floor, Whitla Medical Building Tel: 028 9097 2092 email: c.johnson@qub.ac.uk Module Co-ordinators They provide help and advice on studies relating to their module and are responsible for guidance on remedial study for students who have missed classes because of illness or have failed examinations. Student Guidance Service Students have problems at some point - personal, academic or both, and many find it useful to share these with someone outside the Centre in order to find help and support. For further information: T. (028) 9097 2774 F: (028) 9097 2627 E: counsellor@qub.ac.uk nd Location: 2 Floor, Student Guidance Centre, 91a University Road, Belfast BT7 1NN Website: http://www.qub.ac.uk/directorates/sgc/counselling/ Staff/Student Consultative Committees The Staff/Student Consultative Committee (SSCC) comprises elected student representatives and academic staff. The role of the SSCC is to act as a consultative committee of staff and students on all matters relating to academic welfare, including curriculum review and development. You are encouraged to bring suggestions and comments to the SSCC and to support it actively. Any comments or suggestions should be made to your student representative who will bring them to the next meeting of the SSCC. Minutes of meetings, etc of the SSCC will be posted on the Centre’s web page. 8 YOUR RESPONSIBILITIES Email You must check your Queens e-mail account regularly. This is how we communicate with you. We will only use your official Queens account. Change of Address You must inform the Centre office immediately of any change to your home or term time address. Student Charter and General Regulations The University’s Student Charter sets out how the University will work in partnership with you to support your learning and help you to realise your ambitions, as well as the standards of behaviour and personal responsibility that we expect from our students. The Student Charter can be found at: http://www.qub.ac.uk/directorates/AcademicAffairs/GeneralRegulations/StudentCharter/ By enrolling at Queen’s University Belfast, you undertake to abide by all of our regulations, policies and procedures so it is important that you familiarise yourself with them. The University’s General Regulations contain important information about the rules governing progression, assessment and degree classification on all programmes. They assure the University’s academic standards and ensure all students are treated consistently and equitably. They are also part of the formal contract between you and the University. The University’s General Regulations can be found at: http://www.qub.ac.uk/directorates/AcademicAffairs/GeneralRegulations/ If you have any problems understanding any of these regulations, policies and procedures, or if you have any questions, it is important that you discuss them with your Personal Tutor or the Students’ Union Advice Centre. Absence Students are required to notify the Centre Office of any absences from examinations and compulsory components of their courses and to submit medical certificates or other evidence of extenuating circumstances within three working days of returning to their studies. In the case of emergencies arising during examinations, such written evidence must normally be submitted within three working days of the emergency arising and not later than three working days after the date of their last examination. Exceptional Circumstances If you believe your performance has been adversely affected by exceptional circumstances, you must provide the relevant evidence to the Centre office by the following deadlines; (i) Within three working days of returning to study or, (ii) In the case of emergencies which arose during examinations, by an annual date issued by Central University for both Autumn and Spring semesters. For examinations which take place out of the normal cycle of University examinations, the deadline for submission of Exceptional Circumstances will be set and communicated by your School. Evidence will not be considered after this deadline, unless it is deemed by the Director of Academic and Student Affairs to be of a highly sensitive and confidential nature. The evidence of your exceptional circumstances will be considered by the School Exceptional Circumstances Committee (SEEC) which meets prior to the Board of Examiners’ meeting. It may make recommendations to the Board of Examiners about concessions on the basis of exceptional circumstances. Any documentation you present to the SEEC must be original and provide evidence of your situation or ill health. Retrospective medical certificates will not normally be accepted. This information is detailed on the Student Gateway website at www.qub.ac.uk/studentinfo However, if you need further information about the process; please contact a Sabbatical Officer in the Students’ Union or a member of staff in Academic Affairs on academic-affairs@qub.ac.uk Change of Modules You cannot enrol for or change modules unless you have discussed this with and received the approval of your Adviser of Studies. This option is only available to students on the Human Biology Pathway and can only take place within the first two weeks of the semester. Transferring to another Pathway If you wish to change your degree pathway, it is essential that you discuss this with your Adviser of Studies 9 at the earliest opportunity. Employment during the Academic Year We recognise that some students may have to work part-time whilst completing their degree. There are a number of good reasons for doing this, as part-time work can help you to: • develop valuable employability skills that will impress future employers; • gain experience and a greater understanding of the workplace; • access and develop networking opportunities; • support yourself financially during your studies. However, the University strongly recommends that students on full-time programmes devote NO MORE THAN 15 HOURS PER WEEK TO PAID EMPLOYMENT. There is strong evidence to show that significant levels of part-time work can compromise your academic progress and affect degree outcomes. Please note that International Students may have prohibitions or restrictions on working in the UK. It is very important that you confirm you have a legal right to work and if you do have the right to work, that you don’t exceed the permitted hours. Further information can be found at: http://www.qub.ac.uk/sites/iss/VisaandImmigration/WorkingintheUK/ We do urge you to be sensible about how you manage your study, work and social time to get the best result you can from your degree. If you do have financial pressures that mean you have to work more hours than is advisable, please come and talk to us. Both the Student Income and Finance Department in the Student Guidance Centre and the Students’ Union can give you advice on funds that are available to help students in your position. The Learning Development Service (http://www.qub.ac.uk/directorates/sgc/learning/) can also offer advice on time management. Register with the Student Jobshop to access a range of opportunities and fairly paid part-time jobs at http://www.qub.ac.uk/directorates/sgc/careers/. Punctuality in Attendance at Lectures/Practicals It is standard practice that lectures begin at 5 minutes past the hour and end at 5 minutes to the hour. In fairness to your lecturer and fellow students it is essential that you arrive for classes on time. Mobile phones Please keep mobile phones switched off during lectures, practicals etc. Because of the provisions of the Human Tissues Act they are forbidden in Anatomy practical classes. References and Testimonials Module Co-ordinators, Advisers of Studies, etc are sometimes asked to supply a reference for students. While the majority will be pleased to do so, you must ask their permission before using them as a referee and you must supply them with a typed/electronic copy of your curriculum vitae before the reference is to be prepared. Please also give reasonable notice of your need for a reference. Foundation Scholarships and Prizes Foundation Scholarships will be awarded to the three best candidates at Stage 1 and Stage 2, based on the average mark for the 6 modules taken at each stage. 10 INFORMATION ON GENERAL REGULATIONS Student Feedback Please see the following links for information on student feedback teaching and module evaluations http://www.qub.ac.uk/directorates/AcademicStudentAffairs/CentreforEducationalDevelopment/StudentFeed back/StudentEvaluationofTeaching/ internal student surveys and NSS http://www.qub.ac.uk/directorates/AcademicStudentAffairs/CentreforEducationalDevelopment/StudentFeed back/StudentSurveys/ • Staff Student Consultative Committee http://www.qub.ac.uk/directorates/AcademicStudentAffairs/CentreforEducationalDevelopment/StudentFeed back/StudentRepresentation/ Further details on the Staff Student Consultative Committee for 2015/16 will be posted on our Centre web site at http://www.qub.ac.uk/schools/mdbs/bms/CurrentStudents/StaffStudentConsultativeCommittee/ Academic Misconduct In order to safeguard our academic standards and the integrity of our awards the University has procedures in place for dealing with suspected academic misconduct. The procedure details types of academic misconduct, such as cheating in an examination, plagiarism, collusion and fabrication, how suspected offences are investigated and the penalties that can be imposed. The procedure also details students’ rights of appeal in cases relating to academic misconduct. A Student Guide on the Academic Offences Procedure can be found at: http://www.qub.ac.uk/directorates/AcademicAffairs/AppealsComplaintsandMisconduct/Acade micOffences/Student-Guide/ The full Procedures for Dealing with Academic Offences can be found at: http://www.qub.ac.uk/directorates/AcademicAffairs/GeneralRegulations/Procedures/Procedur esforDealingwithAcademicOffencesincludingresearchmisconduct/ RESEARCH MENTORING PROGRAMME FOR STAGE 1 AND STAGE 2 STUDENTS The Research Mentoring Programme was launched by the Centre for Biomedical Sciences Education in partnership with the Centre for Cancer Research and Cell Biology, the Centre for Vision and Vascular Science, the Centre for Infection and Immunity and the Centre for Public Health. This Programme has been designed to enable you to become acquainted with the international research teams within the School. The Research Mentor Programme also provides you with valuable insights into the world of medical research and enables you to assess the possibilities for your own career and provide a contact scientist who can advise on postgraduate research opportunities and career options. Visits to Research Centres – In your first and second year, you will attend one of the Research Centres once per semester and during this session you will be introduced to the work of the Centre through staff presentations and laboratory demonstrations. During the visits, you will meet your Research Mentor and the Mentor’s Research Team made up of post-doctoral scientists, postgraduate research students and research technicians. Such visits also provide informal opportunities for staff to make contact with interested students for Summer Studentship opportunities in their Centre. 11 Student Reflection - Following each visit, you are asked to write a 200 word summary of the visit, detailing information about the Research Team, the primary research focus of the Team and what you observed on the day. Progression and Degree classifications The University’s Study Regulations set out the rules and procedures that determine your final classification, including: (i) (ii) (iii) The number of credits required to progress to each level of study Mark scales and pass marks for Undergraduate and Postgraduate programmes How your final degree classification is calculated The University’s Study Regulations can be found at: http://www.qub.ac.uk/directorates/AcademicAffairs/GeneralRegulations/StudyRegulations/ 12 Programme Year: 2015-16 Programme Title: Biomedical Science Awarding Institution Queen’s University Belfast Teaching Institution Programme Accredited By The Institute of Biomedical Sciences (IBMS) Final Award BSc (Single Honours) UCAS Code BIOMEDICAL SCIENCE [B940] QAA Benchmarking Group Biomedical Science (Hons) Educational Aims of Programme 1. To provide students with the fundamental knowledge and understanding of the key scientific disciplines and skills relevant to the practice of Biomedical Science. 2. To provide students with the knowledge-base and skills to extend the knowledge and understanding of Biomedical Science through application of scientific method. 3. To develop the student’s ability to apply and communicate knowledge of Biomedical Science to meet the needs of society, fellow Biomedical Scientists and other health professionals. 4. To provide the knowledge and opportunity for students to develop the necessary critical skills to devise, manage and critically evaluate hypothetical proposals related to the practice of Biomedical Science. 5. To enable the students to critically evaluate approaches to clinical laboratory investigation in light of new scientific developments. 6. To provide the knowledge, guidance and opportunity for students to attain competence in subject specific and key skills, problem solving and a professional approach to work, study and life-long learning. 7. To enable students to gain understanding and competence in the generic laboratory skills required in the practice of Biomedical Science. 8. To provide students with a working knowledge of the scientific, practical and ethical aspects of handling specimens of human tissue, cells, blood and body fluids for diagnostic laboratory analysis. 9. To enable students to attain subject-specific knowledge and skills related to the practice of the subspecialties with Biomedical Science as defined by the Institute of Biomedical Science: Cellular Pathology, Clinical Chemistry, Clinical Immunology, Haematology, Immunohaematology & Transfusion Science and Medical Microbiology. For current general University entry requirements for this programme go to http://www.qub.ac.uk/ado Criteria for Admission (Subject Specific Requirements) to Programme Subject specific requirements for this programme are: A-level AB (in any order in Biology/Human Biology and Chemistry) B + GCSE Mathematics OR A (Biology or Chemistry) AB including a second science subject + GCSE Biology and Chemistry or Double Award Science + GCSE Mathematics. Irish Leaving Certificate AB2 (in any order in Biology and Chemistry) B2B2B2 + if not offered at Higher Level then Ordinary Level grade C in Mathematics. 13 Additional Relevant Information Further information is available from the Student Handbook. Study guides will also be issued for each module. Centre for Biomedical Sciences Education st 1 Floor Whitla Medical Building, 97 Lisburn Road, Belfast BT9 7AE Tel: +44(0)28 9097 2043 Fax: +44 (0)28 9097 2174 www.qub.ac.uk/schools/mdbs Email: biomedsci@qub.ac.uk 14 Programme Structure, Levels Modules and Credits Programme Requirements Module Title Module Code Level/ stage Credits Availability Duration Pre-requisite Assessment S1 S2 Core Option Coursework % Examination % Level 1: Students must take the 6 compulsory modules. Human Structure and Function: BMS1001 1 20 12 weeks 30 70 ✓ ✓ Principles Introductory Skills for BSC1009 1 20 12 weeks 60 40 ✓ ✓ Biosciences Genetics and Molecular Biology GEN1005 1 20 12 weeks 30 70 ✓ ✓ Biochemistry BCH1002 1 20 12 weeks 30 70 ✓ ✓ Microorganisms MCB1006 1 20 12 weeks 30 70 ✓ ✓ Human Structure and Function: BMS1002 1 20 12 weeks BMS1001 35 65 ✓ ✓ Systematic Body Systems Level 2: Students must take the 6 compulsory modules Immunobiology BMS2016 2 20 12 weeks 40 60 ✓ ✓ Biomedical Science in Practice BMS2017 2 20 12 weeks 30 70 ✓ ✓ Pathobiology BMS2023 2 20 12 weeks 30 70 ✓ ✓ Molecular Cell Biology BMS2015 2 20 12 weeks 30 70 ✓ ✓ Molecular Genetics BBC2012 2 20 12 weeks 25 75 ✓ ✓ Scientific Methods and BMS2014 2 20 12 weeks 15 85 ✓ ✓ Statistics Optional Placement Year: At the end of Stage 2, students may be offered the opportunity to work as paid Research Assistants in an overseas research laboratory. There are a variable number of placements each year (typically 3-6, depending on available funding). All students applying are interviewed. If the number of applications exceeds the number of placements, the places are awarded on a competitive basis, with student marks also being taken into account. Level 3: All students must take the following 4 compulsory modules. Cellular and Molecular BMS3009 3 20 12 weeks BMS1001, BMS1002 ✓ 30 70 ✓ Haematology Tissue Biology and Pathology BMS3024 3 20 12 weeks BMS1001, BMS1002 ✓ 30 70 ✓ Infections VMI3005 3 20 12 weeks 20 80 ✓ ✓ Clinical Biochemistry BMS3025 3 20 12 weeks BMS2017 40 60 ✓ ✓ Plus one of the alternative routes below depending on whether they qualify for BMS3012 Research Project – Process and BMS3012 3 40 12 weeks 100 0 ✓ ✓ Thesis OR Scientific Literature Project BMS3015 3 20 12 weeks 100 0 ✓ ✓ Developmental Studies BMS3003 3 20 12 weeks BMS1001, BMS1002 25 75 ✓ ✓ 15 Awards, Credits and Progression of Learning Outcomes The following regulations should be read in conjunction with the University’s General Regulations Examinations 1. 2. Students will normally be allowed only 2 attempts at examinations. Supplementary examinations will be provided at the end of the academic year (August/September) regardless of the semester in which modules were actually taken; a student must either have been prevented by illness, or other good reason approved by the School, from sitting that examination, or have failed in the most recent corresponding examination. A student must normally take a supplementary examination at the first opportunity offered by the University. To be awarded a pass for a module, students must achieve a satisfactory performance in all the module’s specified compulsory elements (which in addition to examinations may also include attendance, submission of coursework, etc) as well as achieving an overall pass mark for that module. Where a student has attained an overall pass mark for a module but has not achieved a satisfactory performance in all the specified compulsory elements, the result may, at the discretion of the Board of Examiners, be recorded as incomplete or failed. In the case of incompletion the student’s mark will be referred until the compulsory element is satisfactorily completed and in the case of elements which cannot be repeated within the timescale set, such as attendance at lectures or practicals etc, then the Board of Examiners may set an alternative piece of work to be completed by a stated deadline. 3. At the end of Stage 1, students may be permitted to transfer to the Human Biology programme, subject to approval by their Adviser of Studies and the Academic Selector. 4. For the award of the Honours degree, students must pass BMS3012 (Research Project) or BMS3015 (Scientific Literature Project). 5. For students first enrolled on the programme prior to 2009/10, the following module weightings will be used when calculating the honours classification: Stage 2 25%, Stage 3 75%. 6. For students first enrolled on the programme from 2009/10, the following module weightings will be used when calculating the honours classification: Stage 1 10%, Stage 2 30% and Stage 3 60%. Stage 1 1. In Stage 1 of the Biomedical Science degree students must undertake six modules. 2. In order to proceed to Stage 2 students must have passed the prerequisite module GEN1005 and have no more than one outstanding (i.e. failed or incomplete) Level 1 module. Stage 2 1. In Stage 2 students must undertake the six compulsory modules. 2. In order to proceed to Stage 3 students must have passed all level 1 modules including all programme prerequisite modules and have no more than one outstanding (i.e. failed or incomplete) Level 2 module. 3. In order to be eligible to be enrolled for the module ‘Research Project – Process and Thesis’ (BMS3012) at Stage 3, students must achieve a minimum average score of 55% or higher in Stage 2. This threshold is based on the first attempt integer marks recorded for each of the 6 Level 2 modules, and must be achieved without rounding of marks. Students who fail to attain the threshold score must enrol for the module ‘Scientific Literature Project’ (BMS3015) and take an additional taught module ‘Developmental Studies’ (BMS3003) in Semester 1. 4. With approval of their Advisor of Studies, students who are eligible for but do not wish to undertake BMS3012 may opt for BMS3015 and BMS3003 as the alternative 16 Learning Outcomes: Cognitive Skills 1 On the completion of this course successful students will be able to: Creatively apply scientific principles to new problems and in new situations 2 Analyse and critically evaluate scientific literature 3 Apply ethical and judgemental criteria in relevant fields of study Efficiently summarise large quantities of information and synthesise core concepts from diverse sources 4 Teaching/Learning Methods and Strategies Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Undertaking of Level 3 Research Projects; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Instruction in ethical approval forms for project reports Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Methods of Assessment Project dissertation, lab reports; lab/log book assessment; oral/poster presentations Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written assignments on interpretation and analysis of scientific papers Project Dissertation and supervisor’s report Project dissertation, lab reports; lab/log book assessment; oral/poster presentations Learning Outcomes: Transferable Skills 1 On the completion of this course successful students will be able to: Independent study skills Teaching/Learning Methods and Strategies This is promoted through a range of coursework across all stages of the programme. 2 Written and oral communication 3 IT skills 4 Numerical and data handling skills Completion of written reports, essays, dissertations; oral presentations; Essay writing and peer teaching represent significant components of modules at Level 2 and 3 of the programme and provide excellent opportunity for the development of written and oral communication. Computer skills are developed consistently throughout all stages of study from the initial orientation to the final year project report and presentation. Laboratory practical classes and project work; formal lectures and practical classes in statistics and interpretation 5 Time management Schedule the undertaking and completion of a range of Methods of Assessment Completion of coursework within agreed deadlines; successful completion of study schedules in time for summative assessments Formal oral, poster and written presentations Lab reports; essays; oral and poster presentations; project dissertation. Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written exams and assignments in statistical practice Completion of coursework within agreed deadlines; 17 6 Team working skills coursework and study opportunities within a time-limited framework Teaching through group projects and other learning strategies especially in the second year of studies provides the main vehicle for practical experience of group work. successful completion of study schedules in time for summative assessments The utilisation of both peer and staff assessment of group product quality and individual contribution Learning Outcomes: Knowledge and Understanding 1 On the completion of this course successful students will be able to: To describe, explain and discuss the fundamental Biochemistry, Physiology, Morphology and Molecular Biology underlying human biology and disease 2 To apply the scientific method in the construction and experimental evaluation of hypotheses in Biomedical Science with appropriate data collection, controls and statistical analysis and to compare and contrast the underlying investigative strategies and principles in the laboratory diagnosis of disease 3 To demonstrate understanding in the scientific, practical and ethical aspects of handling specimens of human tissue, cells, blood and body fluids for diagnostic laboratory analysis 4 To describe and discuss the central principles of the pathogenesis of the major classes of human disease and the appropriate diagnostic assays applied to each To discuss the inherent sources of error in the major classes of assay system, employed in Biomedical Science and suggest the appropriate controls to detect such events 5 Teaching/Learning Methods and Strategies Teaching and learning include didactic and active discovery methods with particular emphasis on small group discussions, student/staff-led seminars, oral and written presentations of literature reviews Module practical classes; undertaking of Level 3 Research Projects; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or seminars; one to one discussions with tutor and/or project supervisor; hospital laboratory visits; teaching by hospital-employed Biomedical Scientists Module practical classes; undertaking of Level 3 Research Projects; analysis and discussion of data through the use of examples within class or through the research project; hospital laboratory visits; teaching by hospital-employed Biomedical Scientists Lectures; Module practical classes; coursework; teaching by subject specialists and professionals Methods of Assessment Lectures; Module practical classes; coursework; teaching by subject specialists and professionals Written and practical examinations, coursework Written and practical examinations, coursework Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation Written and practical examinations, coursework Learning Outcomes: Subject Specific Skills On the completion of this course successful students will be able to Each line should contain a different skills outcome Teaching/Learning Methods and Strategies Detail here the corresponding teaching and learning methods that will be employed to ensure students can achieve the stated outcome 1 Interrogate remote online databases 2 Demonstrate competence in the use of statistical software Lectures and practical applications particularly in the Scientific Methods course; level 3 research project. Laboratory practical classes and project work; formal lectures and practical classes in statistics and interpretation Methods of Assessment Detail here the corresponding assessment method which will be used to determine whether a student has achieved the stated outcome. Dissertation of Level 3 Research Project Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written exams and assignments in 18 3 4 Write and prepare the specialized documentation required in medical research: Research reports, papers for submission to peer-review journals and applications to grant-awarding bodies Employ bibliographic software in the completion of essays/dissertations and the documents listed under LO3 5 Work safely in biomedical laboratories 6 Demonstrate competence in the use of general laboratory equipment 7 Demonstrate competence in a limited range of specialized laboratory equipment Lab report and written coursework feedback; Project supervisor feedback Formal didactic teaching and practice in the use of bibliographic software as part of particularly the Scientific Methods module Instruction in safety procedures including relevant paperwork, such as COSHH and ethical approval forms for project reports Module practical classes; undertaking of Level 3 Research Projects; Level 3 Research Project statistical practice Lab reports; Written coursework; Project Dissertation Coursework such as essays; research project dissertation Project Dissertation and supervisor’s report Practical lab reports; formal assessed demonstrations of use of lab equipment Project Dissertation; Project Supervisor Reports 19 Institute of Biomedical Science Accreditation of QUB Biomedical Science Degree Course The QUB Biomedical Science Degree Programme is accredited by the Institute of Biomedical Science (IBMS) http://www.ibms.org/. The IBMS is the professional body for biomedical scientists and has been accrediting biomedical science programmes for over thirty years. Accreditation is a process of peer review and recognition by the profession of the achievement of quality standards for delivering BSc (Hons) biomedical science programmes which conform to the QAA subject benchmark statement for biomedical science (November 2007). Reasons for Institute Accreditation Advances professional practice to benefit healthcare services and professions related to biomedical science Develops specific knowledge and competence that underpins biomedical science Provides expertise to support development of appropriate education and training Ensures curriculum content is both current and anticipatory of future change Facilitates peer recognition of education and best practice and the dissemination of information through education and employer networks Ensures qualification is fit for purpose as an academic qualification acceptable for statutory regulation Recognises the achievement of a benchmark standard of education The degree award meets education requirements for professional body membership. Strengthens links between the professional body, education providers employers and students. Provides eligibility for the Institution (HEI) to become a member of HUCBMS (Heads of University Centres of Biomedical Science) An honours degree in biomedical science accredited by the Institute is acceptable as a preliminary academic qualification for registration with the Health Professions Council (HPC). By undertaking a period of laboratory training and completion of the Institute’s Registration Portfolio for the award of a Certificate of Competence, individuals are able to demonstrate they meet the fitness to practice standards (HPC Standards of Proficiency) required for registration. The Certificate of Competence gives eligibility for Licentiate membership of the Institute. IBMS Careers Information Biomedical scientists work in healthcare to diagnose disease and evaluate the effectiveness of treatment through the analysis of fluids and tissue samples from patients. They provide the 'engine room' of modern medicine with 70% of diagnoses based on the pathology results provided by laboratory services. With biomedical scientists handling an estimated 150 million samples in the UK, every person at some point in their lives will have benefited from their services. For further careers information see: http://www.ibms.org/go/biomedical-science/careers-jobs/careers 20 Associate Membership of the Institute of Biomedical Science Students undertaking the accredited Biomedical Science degree courses can benefit from a period of free Associate membership of the IBMS. The Institute has a package of membership benefits designed to provide both personal and professional support to help Associate members develop their careers, scientific knowledge and expertise. The IBMS also produces a range of publications organises events for all those with an interest in biomedical science. https://www.ibms.org/go/members/join-ibms IBMS President's Prize - An award for graduates from IBMS accredited BSc degree courses The Institute of Biomedical Science sponsors an annual prize for one student graduating from each university offering an Institute accredited BSc (Hons) degree programme in biomedical science. Each university or college awards the prizes according to its own defined criteria to graduates who achieve high academic distinction. Please note the following IBMS conditions for the President's Prize: 1. Student must be an Associate member of the Institute by the end of January of their final year of the degree. (Free Associate membership is acceptable), 2. Each 'President’s Prize' will be £100, 3. The award is presented by either the current President, Regional Council member or Institute nominated region or branch member, 4. A photograph of the award being presented and a synopsis of the winner will be published in The Biomedical Scientist. http://www.ibms.org/go/ibms:prizes-awards:presidents-prize 21 Programme Year: 2015-16 Programme Title: Human Biology Awarding Institution Queen’s University Belfast Teaching Institution Programme Accredited By Final Award BSc (Single Honours) UCAS Code HUMAN BIOLOGY [B100] QAA Benchmarking Group Biosciences (Hons) Educational Aims of Programme On completion of the programme, students should be able to: 1. Integrate knowledge from a range of human biology disciplines, including the anatomical and physiological sciences, in order to gain a fundamental understanding of the normal structure and function of the human organism at molecular, cell, organ and system levels. 2. Link normal structure and function with some examples of the abnormal, including how these can be modified through intervention. 3. Demonstrate clear and systematic understanding of specialised areas of human biology knowledge and skills. 4. Demonstrate practical skills relevant to a variety of disciplines in human biology. 5. Apply the scientific method in the construction and experimental evaluation of hypotheses in human biology with appropriate data collection and statistical analysis. 6. Interpret scientific and other data and demonstrate critical awareness of the quality of evidence 7. Demonstrate well developed transferable skills, including communication, team work, scientific writing and oral presentation 8. Plan, execute and present an independent piece of work. 9. Demonstrate qualities such as efficient time management and problem solving. 10. Utilise well developed self-learning strategies for maintaining, updating and enhancing knowledge. For current general University and subject specific entry requirements for this programme go to http://www.qub.ac.uk/ado Criteria for Admission (Subject Specific Requirements) to Programme Subject specific requirements for this programme are: A-level AB (in any order in Biology/Human Biology and Chemistry) B + GCSE Mathematics OR A (Biology or Chemistry) AB including a second science subject + GCSE Biology and Chemistry or Double Award Science + GCSE Mathematics. Irish Leaving Certificate AB2 (in any order in Biology and Chemistry) B2B2B2 + if not offered at Higher Level then Ordinary Level grade C in Mathematics. Further Information Further information is available from the Student Handbook. Study guides will also be issued for each module. 22 Or contact: Centre for Biomedical Sciences Education st 1 Floor Whitla Medical Building, 97 Lisburn Road, Belfast BT9 7AE Tel: +44(0)28 9097 2043 Fax: +44 (0)28 9097 2174 www.qub.ac.uk/schools/mdbs Email: biomedsci@qub.ac.uk 23 Programme Structure, Levels, Modules and Credits Module Title Module Code Level/ stage Credits Availability Duration Pre-requisite Assessment S1 S2 Core Option Coursework % Examination % Level 1: Students must take all six compulsory modules. Human Structure and Function: BMS1001 1 20 12 weeks 30 70 ✓ ✓ Principles Introductory Skills for Biosciences BSC1009 1 20 12 weeks 60 40 ✓ ✓ Genetics and Molecular Biology GEN1005 1 20 12 weeks 30 70 ✓ ✓ Human Structure and Function: BMS1002 1 20 12 weeks BMS1001 35 65 ✓ ✓ Systematic Body Systems Microorganisms MCB1006 1 20 12 weeks 30 70 ✓ ✓ Biochemistry BCH1002 1 20 12 weeks 30 70 ✓ ✓ Level 2: Students must take a total of six modules including the compulsory module, one module listed under Group A and one module listed under Group B. The remaining modules may be chosen from the optional modules listed in Group A, Group B or Group C. One of these three modules may be substituted by a module of equivalent or higher level, subject to the approval of the Adviser of Studies. Scientific Methods and Statistics BMS2014 2 20 12 weeks 15 85 ✓ ✓ Cells and Tissues BMS2026 2 20 12 weeks BMS1001; BMS1002 60 ✓ ✓ (Group A) 40 Topographical Anatomy 1 BMS2001 2 20 12 weeks BMS1001; BMS1002 50 ✓ ✓ (Group A) 50 Cardiovascular and Respiratory BMS2007 2 20 12 weeks BMS1001; BMS1002 60 ✓ ✓ (Group B) 40 Physiology Exercise and Applied Physiology BMS2008 2 20 12 weeks BMS1001; BMS1002 60 ✓ ✓ (Group B) 40 Drugs and the Human Body BMS2027 2 20 12 weeks BMS1001; BMS1002 60 ✓ ✓ (Group B) 40 Human Physiological BMS2028 2 20 12 weeks BMS1001, BMS1002 50 ✓ ✓ (Group B) 50 Measurement Immunobiology BMS2016 2 20 12 weeks 60 ✓ ✓ (Group C) 40 Pathobiology BMS2023 2 20 12 weeks 30 70 ✓ ✓ (Group C) Diet and Health ALU2008 2 20 12 weeks 70 ✓ ✓ (Group C) 30 Optional Placement Year: At the end of Stage 2, students may be offered the opportunity to work as paid Research Assistants in an overseas research laboratory. There are a variable number of placements each year (typically 3-6, depending on available funding). All students applying are interviewed. If the number of applications exceeds the number of placements, the places are awarded on a competitive basis, with student marks also being taken into account. Level 3: Students must take a total of six modules, including either BMS3012 or BMS3015 and one module from Group A. The remaining three/four modules may be chosen from the optional modules listed in Group A or Group B. Research Project Process and BMS3012 3 40 12 weeks 100 0 ✓ ✓ (choice Thesis of either Scientific Literature Project BMS3015 3 20 12 weeks 100 0 module) ✓ Advanced Cardiovascular BMS3005 3 20 12 weeks BMS1001; BMS1002 60 ✓ ✓ (Group A) 40 Physiology Neuroscience BMS3002 3 20 12 weeks BMS1001; BMS1002 70 ✓ ✓ (Group A) 30 Topographical Anatomy 2 BMS3011 3 20 12 weeks BMS1001; 50 ✓ ✓ (Group A) 50 BMS1002; BMS2001 Developmental Studies BMS3003 3 20 12 weeks BMS1001; BMS1002 75 ✓ ✓ (Group A) 25 24 Module Title Module Code Level/ stage Credits Availability Tissue Biology and Pathology Vascular Biology Molecular Pharmacology BMS3024 BMS3027 TPU3001 3 3 3 20 20 20 Cardiovascular Pharmacology TPU3006 3 20 ✓ 12 weeks Integrated Pharmacology TPU3008 3 20 ✓ 12 weeks Cellular and Molecular Haematology Clinical Nutrition Science in Education BMS3009 3 20 SCM3001 EDU3009 3 3 20 20 S1 S2 ✓ ✓ ✓ ✓ Duration Pre-requisite 12 weeks 12 weeks 12 weeks BMS1001, BMS1002 BMS1001; BMS1002 BMS1001; BMS1002 (BMS2027 beneficial) BMS1001; BMS1002 (BMS2007; BMS2027 beneficial) BMS1001; BMS1002 (BMS2027 beneficial) BMS1001, BMS1002 Core 12 weeks ✓ ✓ Assessment 12 weeks 12 weeks ALU2008 Option ✓ (Group A) ✓ (Group A) ✓ (Group B) Coursework % 30 30 40 Examination % 70 70 60 ✓ (Group B) 40 60 ✓ (Group B) 40 60 ✓ (Group B) 30 70 ✓ (Group B) ✓ (Group B) 40 60 Workshop + Placement 25 Awards, Credits and Progression of Learning Outcomes The following regulations should be read in conjunction with the University’s General Regulations. Examinations 1. 2. Students will normally be allowed only 2 attempts at examinations. Supplementary examinations will be provided at the end of the academic year (August/September) regardless of the semester in which modules were actually taken; To be allowed to enter for a supplementary examination a student must either have been prevented by illness, or other good reason approved by the School, from sitting that examination, or have failed in the most recent corresponding examination. A student must normally take a supplementary examination at the first opportunity offered by the University. To be awarded a pass for a module, students must achieve a satisfactory performance in all the module’s specified compulsory elements (which in addition to examinations may also include attendance, submission of coursework, etc) as well as achieving an overall pass mark for that module. Where a student has attained an overall pass mark for a module but has not achieved a satisfactory performance in all the specified compulsory elements, the result may, at the discretion of the Board of Examiners, be recorded as incomplete or failed. In the case of incompletion the student’s mark will be referred until the compulsory element is satisfactorily completed and in the case of elements which cannot be repeated within the timescale set, such as attendance at lectures or practicals etc, then the Board of Examiners may set an alternative piece of work to be completed by a stated deadline. 3. At the end of Stage 1, students may be permitted to transfer to the Biomedical Science programme, subject to approval by their Adviser of Studies and the Academic Selector. 4. For the award of the Honours degree, students must pass BMS3012 (Research Project) or BMS3015 (Scientific Literature Project). 5. For students first enrolled on the programme prior to 2009/10, the following module weightings will be used when calculating the honours classification: Stage 2 25%, Stage 3 75%. 6. For students first enrolled on the programme from 2009/10, the following module weightings will be used when calculating the honours classification: Stage 1 10%, Stage 2 30% and Stage 3 60%. 7. For students permitted to transfer from other courses to the Human Biology programme at stage 3, the classification will be based on the weighted average of the modules taken at level 3. Stage 1 1. 2. In Stage 1 of the Human Biology degree, students must take the six compulsory modules. In order to proceed to Stage 2, students must have passed the programme pre-requisite modules BMS1001 and BMS1002, and have no more than one outstanding (i.e. failed or incomplete) Level 1 module. Stage 2 1. 2. 3. Students must take six Level 2 modules. In order to proceed to Stage 3 students must have passed all Level 1 modules including all programme pre-requisite modules; and they must have no more than one outstanding (i.e. failed or incomplete) Level 2 module. In order to be eligible to be enrolled for the module ‘Research Project – Process and Thesis’ (BMS3012) at Stage 3, students must achieve a minimum average score of 55% or higher in Stage 2. This threshold is based on the first attempt integer marks recorded for each of the 6 level 2 modules, and must be achieved without rounding of marks. Students who fail to attain the threshold score must enrol for the module ‘Scientific Literature Project’ (BMS3015) and take an additional taught module in Semester 1. With approval of their Advisor of Studies students who are eligible for but do not wish to undertake BMS3012 may opt for BMS3015 and one other module as an alternative. 26 Learning outcomes, teaching and assessment methods Learning Outcomes: Cognitive Skills On the completion of this course successful students will be able to: Teaching/Learning Methods and Strategies Methods of Assessment generate hypotheses and analyse these using decision-making processes which satisfy safety and accountability procedures Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation analyse personally generated data from designed experimental situations in order to formulate and synthesise concepts Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Module practical classes; undertaking of Level 3 Research Projects; small group discussion; analysis and discussion of data through the use of examples within class or through the research project; formative assessment with class discussion and presentation of journal papers, posters or students talks; one to one discussions with tutor and/or project supervisor Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation integrate, interpret and synthesise data from a variety of sources to formulate hypotheses and defend them in an appropriate manner employ critical analysis in order to interpret and synthesise concepts judge the ethical aspects of specific issues within human biology Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation Practical lab reports; written and practical examinations; oral and poster presentations; Research Project dissertation Learning Outcomes: Transferable Skills On the completion of this course successful students will be able to: Teaching/Learning Methods and Strategies Methods of Assessment deduce outcomes using a range of relevant problem-solving approaches Module lab-based classes; problem-solving activities through coursework; Level 3 Research Project Schedule the undertaking and completion of a range of coursework and study opportunities within a time-limited framework Practical lab reports; completion of coursework; written exams particularly at Level 3 Completion of coursework within agreed deadlines; successful completion of study schedules in time for summative assessments Formal oral, poster and written presentations Practical lab reports; formal assessed demonstrations of lab skills and their outcomes Level 3 research dissertation manage their time efficiently communicate ideas effectively both in writing and orally carry out a variety of practical and laboratory procedures Completion of written reports, essays, dissertations; oral presentations; Module lab based classes; Lab-based research project use successful strategies for fostering and developing present knowledge work as effective members of a team promotion of active learning ( by doing) in labbased classes small group projects; assessment using observed structured behavioural examinations, where the effectiveness of a team and its members is determined; completion of group project assignments. 27 Learning Outcomes: Knowledge and Understanding On the completion of this course successful students will be able to: Teaching/Learning Methods and Strategies Methods of Assessment describe and discuss an extensive range of concepts within human biology student-centred learning, including oral and written presentations of literature, supported by lectures, tutorials, seminars and practical classes; dynamic, modern learning environment; online technology to support student learning; Formative assessments to promote engagement and comprehension student-centred learning, including oral and written presentations of literature, supported by lectures, tutorials, seminars and practical classes; dynamic, modern learning environment; online technology to support student learning; Formative assessments to promote engagement and comprehension student-centred learning, including oral and written presentations of literature, supported by lectures, tutorials, seminars and practical classes; dynamic, modern learning environment; online technology to support student learning; Formative assessments to promote engagement and comprehension summative assessment through course work and appropriate written and practical examinations; portfolio, demonstrating reflective practice apply acquired knowledge to analyse critically, interpret and illustrate comprehension of established concepts in specific areas of human biology discuss and evaluate the application of new or emerging concepts in a range of learning contexts, using data from a variety of human biology sources summative assessment through course work and appropriate written and practical examinations; portfolio, demonstrating reflective practice summative assessment through course work and appropriate written and practical examinations; portfolio, demonstrating reflective practice Learning Outcomes: Subject Specific Skills On the completion of this course successful students will be able to Teaching/Learning Methods and Strategies Methods of Assessment demonstrate competence in following experimental procedures and practical methodologies in human biology Completion of Level 3 Research Project; experiential learning in practical classes, tutorials and seminars; formative assessment in the form of written course work, including reflective practical reports, laboratory records and logbooks Laboratory practical classes and project work Project dissertation, lab reports; lab/log book assessment; oral/poster presentations demonstrate good observational skills document and present data, applying statistical analysis where appropriate Laboratory practical classes and project work; formal lectures and practical classes in statistics and interpretation evaluate and interpret scientific data using a variety of appropriate methods Laboratory practical classes and project work; Coursework assignments particularly at level 3 apply and judge the significance of a range of human biology concepts in a work-related context Laboratory practical classes and project work; Coursework assignments particularly at level 3 comply with ethical practice for biological specimens, health and safety, and other relevant legislation Instruction in safety procedures including relevant paperwork, such as COSHH and ethical approval forms for project reports Project dissertation, lab reports; lab/log book assessment; oral/poster presentations Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written exams and assignments in statistical practice Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written assignments on interpretation and analysis of scientific papers Project dissertation, lab reports; lab/log book assessment; oral/poster presentations; written assignments on interpretation and analysis of scientific papers Project Dissertation and supervisor’s report 28 TIMETABLES Level 1 Modules – Indicative Timetable Only SEMESTER 1 Monday 09.00-10.00 10.00-11.00 BSC1009 11.00-12.00 12.00-13.00 Tuesday BMS1001 BMS1001 BSC1009P GEN1005P BMS1001 BSC1009P GEN1005P BSC1009P Wednesday GEN1005 GEN1005P 13.00-14.00 14.00-15.00 15.00-16.00 16.00-17.00 17.00-18.00 GEN1005P GEN1005P GEN1005P GEN1005P BMS1001 SEMESTER 2 Monday Tuesday BMS1002 BMS1002 BCH1002P BMS1002 BCH1002P BMS1002 BCH1002P 09.00-10.00 10.00-11.00 11.00-12.00 12.00-13.00 13.00-14.00 14.00-15.00 15.00-16.00 16.00-17.00 MCB1006 BCH1002 BCH1002P BCH1002P MCB1006P MCB1006P Thursday BMS1001 BMS1001 BSC1009P GEN1005P BMS1001 BSC1009P GEN1005P BMS1001 Friday BSC1009 GEN1005 BSC1009P GEN1005P BSC1009P BSC1009P BSC1009P Wednesday MCB1006 BCH1002 Thursday Friday BMS1002 BMS1002 BCH1002P BMS1002 BCH1002P BMS1002 BCH1002P BCH1002 MCB1006 MCB1006T MCB1006P MCB1006P Timetable will be confirmed and arrangements for practical classes made at your first lecture (see date/venue in module information). P denotes probable practical class times. 29 Level 2 Modules – Indicative Timetable Only SEMESTER 1 Monday Tuesday Wednesday Thursday Friday 09.00-10.00 BMS2026 BMS2023 BMS2007 BBC2012T BMS2007 BBC2012 BBC2012 BMS2027 10.00-11.00 BMS2026 BMS2023 BMS2026 BMS2026 BMS2023 BBC2012L BMS2023 BMS2007 BMS2016 BMS2007 BMS2007 BMS2027 11.00-12.00 12.00-13.00 BMS2007 BMS2016 BMS2007 BMS2007 BMS2026 BMS2023 BBC2012P BBC2012P BMS2016 BBC2012P BMS2027 BBC2012P BMS2023 BMS2026 BBC2012P BMS2026 BBC2012P BMS2016 BBC2012P BBC2012P BMS2016 BBC2012P Monday Tuesday Wednesday Thursday Friday ALU2008 ALU2008 BMS2014 BMS2015 ALU2008 BMS2015 ALU2008 BMS2014 13.00-14.00 14.00-15.00 15.00-16.00 16.00-17.00 SEMESTER 2 09.00-10.00 BMS2027 BMS2027 BMS2008 BMS2028 BMS2008 BMS2017 BMS2028 BMS2008 ALU2008P BMS2008 ALU2008P ALU2008 BMS2008 BMS2017 BMS2028 BMS2008 ALU2008P BMS2015 ALU2008 BMS2015 BMS2015 ALU2008 BMS2014 BMS2017 BMS2028 BMS2001 BMS2017 BMS2015P ALU2008 ALU2008 BMS2001 ALU2008 BMS2017P BMS2015P 15.00-16.00 BMS2028 BMS2017 BMS2001 BMS2017P BMS2015P 16.00-17.00 BMS2028 BMS2017 BMS2001 BMS2017 BMS2015P ALU2008 BMS2001 BMS2017 BMS2015P ALU2008 BMS2001 BMS2017P BMS2015P 10.00-11.00 11.00-12.00 12.00-13.00 13.00-14.00 14.00-15.00 17.00-18.00 ALU2008 BMS2014 BMS2001 Timetable will be confirmed and arrangements for practical classes made at your first lecture (see date/venue in module information). P denotes probable practical class times. 30 Level 3 Modules – Indicative Timetable Only SEMESTER 1 Monday Tuesday Wednesday Thursday BMS3011 09.00-10.00 Friday TPU3001 10.00-11.00 BMS3009 BMS3011 BMS3003 TPU3001 11.00-12.00 BMS3009 BMS3011 BMS3003 TPU3001 12.00-13.00 BMS3009 BMS3011 BMS3003 TPU3001 13.00-14.00 14.00-15.00 BMS3009 BMS3011 TPU3001 15.00-16.00 BMS3011 TPU3001 16.00-17.00 BMS3011 SEMESTER 2 Monday Tuesday Wednesday Thursday Friday 09.00-10.00 BMS3002 TPU3006 TPU3008 BMS3005 BMS3025 BMS3005 BMS3005 SCM3001 BMS3025 BMS3005 10.00-11.00 BMS3002 TPU3006 TPU3008 BMS3024 BMS3024 11.00-12.00 BMS3002 TPU3006 TPU3008 BMS3005 SCM3001 BMS3025 BMS3005 BMS3024 12.00-13.00 BMS3002 TPU3006 TPU3008 VMI3005 BMS3005 SCM3001 BMS3025 BMS3005 BMS3024 13.00-14.00 14.00-15.00 VMI3005 15.00-16.00 16.00-17.00 SCM3001 EDU3009 VMI3005 BMS3027 BMS3024 EDU3009 VMI3005 BMS3027 BMS3024 EDU3009 VMI3005 BMS3027 BMS3024 Level 3 also includes the compulsory Research Project and Thesis BMS3012 in semester 1. 31 MODULE TITLE MODULE CODE SUMMARY HUMAN STRUCTURE AND FUNCTION: PRINCIPLES BMS1001 Year-1 Module Semester-1 (September-December) Introduction to the gross structure and function of the human body: Structure and function of the four main tissue types and their role within the major organ systems. The gross organisation, histology and physiology of the musculo-skeletal, nervous, and endocrine systems. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr A Al-Modhefer LECTURES CONTACT TEACHING No 40 4 TUTORIALS 15 PRACTICALS On completion of this module you will be able to: LEARNING OUTCOMES SKILLS Total Hours 40 4 30 1. Describe the structure and function of cellular organelles. 2. Describe the structure of the cell membrane and discuss its role in transmembrane transport. 3. Describe the structure and function of the various types of epithelium and connective tissue. 4. Describe the structure and ultrastructure of muscle and outline the sliding filament hypothesis of muscle contraction. 5. Outline the events that occur during neuromuscular and synaptic transmission. 6. Discuss homeostasis and give examples of homeostatic control systems. 7. Explain how membrane potentials arise and their significance in excitable cells. 8. Describe the general structural and function arrangement of the nervous system. 9. Describe how the major sense organs are stimulated and respond to external stimuli. 10. Describe the hypothalamus-pituitary axis and the structure and function of the main endocrine glands: thyroid, parathyroid, adrenal, pancreas. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Use of the specialised language of anatomy and physiology Safe handling of body fluids Use of microscope and virtual slides Use of laboratory instruments ensuring accuracy and reliability Interpretation of laboratory results Problem solving Communication Literacy through the completion of laboratory reports Numeracy including the collection, analysis and interpretation of data Working as individuals and as part of a team 32 MODULE TITLE MODULE CODE BRIEF SUMMARY MANAGING SCHOOL MODULE COORDINATOR CONTACT TEACHING INTRODUCTORY SKILLS FOR BIOSCIENCES BSC1009 Year-1 Module Semester-1 (September-December) 1. Introduction to a personal development planning and reflective practice. 2. Employ the scientific method and experimental design in a Bioscience research area through completion of a group research project. 3. Development of a range of basic practical bioscience laboratory skills. 4. Introduction to basic statistical analysis through Minitab computer packages. 5. Introduction to the scientific literature: remote database searches, critical analysis and written scientific communication. Biological Sciences Dr T Caruso / Dr Johnathan Dalzell No 19 Total Hours 19 0 0 11 33 LECTURES TUTORIALS PREREQUISITES LEARNING OUTCOMES SKILLS PRACTICALS None Knowledge On completion of this module successful students will be able to: 1) Engage in reflective learning and continue development of their personal development portfolio. 2) Employ the scientific method to generate testable hypotheses and appropriate experimental designs for investigation of novel problems in the biosciences. 3) Suggest appropriate statistical analysis for data derived from simple experiments in the biosciences. 4) Apply the basic principles of critical assessment to the scientific literature. 5) Efficiently search the scientific literature and cite it appropriately in written documents. 6) Discuss basic biotechnology. 7) Outline the principles of good laboratory practice. Information technology, written and oral communication, numerical procedures, introductory statistics, using databases, presentation and interpretation of scientific data, experimental design and surveys, biochemical and molecular techniques, microscopy, good laboratory practice and personal development planning (PDP). 33 MODULE TITLE MODULE CODE BRIEF SUMMARY GENETICS AND MOLECULAR BIOLOGY GEN1005 Year-1 Module Introduction to biomolecules, principally amino acids, proteins and DNA, emphasising the structure producing function. The genetic process from DNA sequence via protein synthesis to functional protein. Modes of inheritance, multifactorial traits, population genetics and evolution. MANAGING SCHOOL Biological Sciences MODULE COORDINATOR Dr Mark Robinson LECTURES CONTACT TEACHING Semester-1 (September-December) No 33 Total Hours 33 9 27 TUTORIALS PRACTICALS/ WORKSHOPS LEARNING OUTCOMES SKILLS OTHER (please indicate) On completion of this module each student should be able to: 1. Describe the structure and roles of the major types of biomolecules with emphasis on DNA, RNA, amino acids and proteins. 2. Perform some of the techniques used to study DNA, RNA, amino acids and proteins.. 3. Describe the nature of the genetic code, its translation into proteins, and hence its effect on the phenotype by biochemical activity. 4. Describe the structure of prokaryotic and eukaryotic chromosomes. 5. Discuss the effects of independent segregation, linkage and recombination on phenotype frequencies in successive generations. 6. Outline methods of predicting frequencies and calculating linkage. 7. Explain continuous and discontinuous variation in genetically determined characteristics. 8. Discuss the interaction of phenotypes with environmental factors which thus cause evolution by selection. 9. Identify the methods used to study allele frequencies at the population level, including the Hardy – Weinberg equilibrium prediction, its calculation, interpretation and use. 10. Discuss how bioinformatics is useful in the identification of genes, prediction of protein structure and function and how it can be used to inform functional genomics. Laboratory skills (liquid handling and dilution, spectrophotometry, pH). Critical and logical analysis of data. Use of computers for self-teaching and assessment. 34 MODULE TITLE MODULE CODE BRIEF SUMMARY MODULE COORDINATOR MICROORGANISMS MBC1006 Year-1 Module The aim of this course is to provide a thorough grounding in the range of diversity of microorganisms, their structure, nutrition, growth, physiology and genetics. Also to provide 'hands-on' practical experience in the isolation and cultivation of microorganisms. This is done through individual laboratory experiments. Additionally the students work on a group project report that alongside tutorials enable them to acquire knowledge through independent efforts. The project topics and tutorials are degree specific – thus Biomedical Science students work on topics related to microbial disease only. To be confirmed LECTURES CONTACT TEACHING Semester-2 (February to May) No 35 4 Total Hours 35 4 5 15 Group assignment 15 TUTORIALS PRACTICALS OTHER (please indicate) LEARNING OUTCOMES SKILLS On completion of this module each student should be able to: 1. Describe the structure and major biological characteristics of bacteria, fungi and viruses. 2. Outline the important roles of microorganisms in the environment. 3. Describe the interactions of microorganisms with humans and animals. 4. Discuss the role of microorganisms in disease. 5. Discuss the biotechnological potential of microorganisms. 6. Isolate and cultivate microorganisms aseptically. 7. Enumerate microbial cell populations. 8. Calculate growth rates of microbial cells. 9. Perform basic characterisations of microorganisms including microscopic and biochemical analysis. 10. Working as individuals, they gain from the practical course an ability to isolate and cultivate microorganisms aseptically, enumerate microbial cell populations, calculate growth rates and carry out basic characterizations including microscopic and biochemical analyses. Numeracy skills are at the core of the practicals From group project work they also gain experience in working with groups, time management and report writing. This includes literature searching on topics that are degree related and development of strategies for report writing. 35 MODULE TITLE MODULE CODE BRIEF SUMMARY BIOCHEMISTRY BCH1002 Year-1 Module The module provides an theoretical and practical introduction to the chemical basis of life through the study of macromolecular structures, enzymes, metabolic pathways and the regulation of metabolism. MANAGING SCHOOL Biological Sciences MODULE COORDINATOR Dr David Timson (Biological Sciences) LECTURES CONTACT TEACHING Semester-2 (February to May) No 35 0 Total Hours 35 0 6 18 TUTORIALS PRACTICALS LEARNING OUTCOMES SKILLS OTHER (please indicate) On completion of this module students will be able to: 1) Describe structure and properties of enzymes including enzyme kinetics, the effect of pH and temperature and the effects of inhibitors. 2) Describe the structure of amino acids and protein and explain the principles of protein sequencing. 3) Outline the structure, function and classification of lipids and their relationship to membrane structure. 4) Describe the function and structure of mono-, di- and polysaccharides. 5) Outline the function, sequence and cellular compartmentalisation of the major metabolic pathways, including glycolysis, the tricarboxylic acid cycle, oxidative phosphorylation, the pentose monophosphate shunt, and beta oxidation of lipids. 6) Explain the urea cycle and nitrogen excretion. 7) Discuss the role of hormones in the control of metabolism. Laboratory skills (including enzyme assays, handling of biological material including mammalian tissue, spectrophotometry, thin layer chromatography, paper chromatography); Numerical analysis of data; Graph plotting; Group working; Written communication; Reflection on own learning; Use of books and online resources to support learning; Problem solving including cases where data may be incomplete or lacking; Critical analysis of experimental data. 36 MODULE TITLE MODULE CODE SUMMARY MODULE CO ORDINATOR HUMAN STRUCTURE AND FUNCTION: BODY SYSTEMS BMS1002 LEARNING OUTCOMES Semester-2 (February to May) Basic human anatomy and physiology course consisting of lectures, practicals and tutorials. Describes the anatomy and physiology of the cardiovascular, lymphatic, respiratory, gastrointestinal, urinary and reproductive systems. Dr Etain Tansey & Dr Aisling Keane LECTURES CONTACT TEACHING Year-1 Module No Total Hours 39 39 TUTORIALS 5 7 PRACTICALS 15 30 OTHER (please indicate) On completion of this module you will be able to: 1. Describe the general structure and function of the cardiovascular system. 2. Describe the composition of blood and explain the major functions of red and white cells. 3. Explain the functional significance of blood groups, blood clotting and haemostasis. 4. Outline the importance of water in the normal homeostasis of the body and explain how its distribution between compartments occurs. 5. Explain the mechanisms of water-electrolyte and acid-base regulation in the body. 6. Describe the structure and explain the function of the kidneys and urinary system. 7. Describe the structure and arrangement of the gastrointestinal tract and its associated glands. 8. Explain digestion and absorption in the gastrointestinal tract. 9. List the major functions of the liver. 10. Describe the organisation and function of the smooth muscle in the gastrointestinal tract. 11. Describe the structure and function of the respiratory system. 12. Explain how the respiratory gases are transported between the lungs and the tissues and chemical regulation of blood gases. (Skills as for BMS1001 above) 37 MODULE TITLE MODULE CODE SUMMARY IMMUNOBIOLOGY BMS2016 Year-2 Module Semester-1 (September-December) Basic introduction to the general principles of immunology: the cells and organ systems that make up the immune system. The subjects covered include, innate and adaptive immunity, cell mediated immunity and antibody mediated immunity, how the host defense works to protect us against microbes and other invading pathogens. The course outlines how the cells and soluble components of the immune system work, particularly with regard to phagocytosis, T & B-cell activation, cytokine release, cytokine function, antigen presentation. The course also provides an introductory outline of diseases of the immune system, particularly autoimmune disease, allergy, immunodeficiency and therapies, particularly transplantation, vaccination and antibody-mediated therapy. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Adrien Kissenpfennig LECTURES CONTACT TEACHING LEARNING OUTCOMES No 15 4 Total Hours 30 10 TUTORIALS 5 15 PRACTICALS By the end of this module students will be able to:1. Describe the cells, tissues and soluble factors responsible for innate and adaptive immunity. 2. Explain the mechanisms of antigen presentation and antibody mediated antigen attack. 3. Outline the mechanisms through which the immune system deals with pathogens. 4. Describe and discuss hypersensitivity and auto-immunity. Practical laboratory skills: 1. Practical skills in working with cells of the immune system in vitro. 2. Practical skills in working with antibodies and sera. 3. Immunohistochemical staining. 4. ELISA 5. Flow Cytometry and FACS SKILLS Transferable skills: 1. Problem solving and critical analysis of information 2. Use of information technology for acquisition of study material from the WWW and remote databases 3. Team working 4. Time management and prioritisation of tasks 5. Preparation and delivery of oral presentations using Microsoft PowerPoint 38 MODULE TITLE PATHOBIOLOGY MODULE CODE BMS2023 SUMMARY Year-2 Module Semester-1 (September-December) The aim of this course is to provide students with an integrated knowledge of the fundamental mechanisms and causative factors in human disease. The basic mechanisms of cell death and injury, acute and chronic inflammation, haemostasis and wound healing and the development of cancer are covered in the context of human tissues while the pathogenesis of haematological and infectious disease are dealt with separately. The tissue pathology and haematology are illustrated in virtual pathology practical classes. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Prof Ken Mills LECTURES CONTACT TEACHING No 36 1 Total Hours 36 1 3 6 TUTORIALS PRACTICALS LEARNING OUTCOMES SKILLS By the end of this module you will be able to: 1) Discuss the causes, mechanisms and effects of common human disease. 2) Describe the characteristics, causes, mechanisms and diagnosis of blood disorders. 3) Discuss infectious diseases and their prevention, diagnosis and treatment. 4) Explain the pathogenic mechanisms responsible for virulence in bacterial pathogens. 5) Discuss the mechanisms of antibiotic resistance. 6) Discuss common viruses in the clinical and diagnostic setting. 7) Outline the role of laboratory medicine in the investigation and diagnosis of disease. Critical thinking Use of the scientific literature Virtual microscopy 39 MODULE TITLE MOLECULAR GENETICS MODULE CODE BBC2012 BRIEF SUMMARY The aim of this course is to provide students with a fundamental understanding of gene transcription and translation. The practical side of the module should impart students with basic competence in molecular cloning. Year-2 Module MANAGING SCHOOL School of Biological Sciences MODULE COORDINATOR Dr Kostya Panov CONTACT TEACHING LEARNING OUTCOMES SKILLS Semester-1 (September-December) No Total Hours LECTURES 29 29 TUTORIALS 3 6 PRACTICALS 8 24 OTHER (please indicate) 1 2 By the end of this module a successful student will be able to: 1. Describe the structure and organisation of prokaryotic and eukaryotic genomes. 2. Describe the structure and organisation of prokaryotic, eukaryotic and viral genes. 3. Explain how genetic information is transferred. 4. Explain how gene expression is controlled. 5. Describe how mutations affect protein function 6. Employ state of the art techniques used in recombinant DNA technology 7. Employ a basic bioinformatic tool (BLAST- Basic Local Alignment Search Tool) for interrogation of gene sequences in a remote online data base. Analysis of experimental results; integration of a diversity of experimental approaches; identification of the applications of 'pure' research. 40 MODULE TITLE MODULE CODE SUMMARY DRUGS AND THE HUMAN BODY BMS2027 Year-2 Module Semester-1 (September -December) A study of the basic principles governing the effect of drugs on the human body. Includes identification of subcellular drug targets and their associated signal transduction pathways. Drug action at these subcellular targets will be illustrated by the extensive use of examples, with particular reference to drugs affecting activity of the peripheral nervous system, the renal, cardiovascular and respiratory systems. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Laura Montgomery LECTURES CONTACT TEACHING No 16 6 Total Hours 16 6 3 6 TUTORIALS PRACTICALS LEARNING OUTCOMES SKILLS By the end of this module you will be able to: 1) Discuss ion channels, transporter proteins, enzymes and receptors as subcellular drug targets and describe their associated signal transduction pathways. 2) List the different types of neurotransmitters operating in the peripheral and central nervous systems and describe their actions. 3) Explain how the activity of peripheral neurotransmitters may be modified to restore normal function in a variety of body systems. 4) Explain how vasodilator positive inotropic drugs and beta-blocker drugs can be used to restore normal cardiovascular function. 5) Explain the action of diuretics on the kidney and discuss their use in the treatment of cardiovascular dysfunction. 6) Discuss the use of bronchodilator for the restoration of normal respiratory function. Written communication Poster presentation Quantitative analysis and data manipulation 41 MODULE TITLE MODULE CODE SUMMARY CARDIOVASCULAR AND RESPIRATORY PHYSIOLOGY BMS2007 Year-2 Module Semester-1 (September -December) An intermediate level study of cardiovascular and respiratory physiology with an emphasis on the application of this knowledge to problem solving in clinical scenarios. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Etain Tansey LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS No 24 24 Total Hours 24 24 TUTORIALS 6 12 PRACTICALS By the end of this module you will be able to: 1) Explain static lung mechanics in terms of lung volumes, inflation pressure and compliance as determined by the physical properties of the organ 2) Explain dynamic lung mechanics as determined by airway resistance. 3) Discuss factors affecting airway resistance: bronchial smooth muscle, its innervation, and regulatory mechanisms 4) Explain the principles governing the transfer of oxygen and carbon dioxide across the alveolocapillary membrane. 5) Discuss the regulation of breathing by the nervous system including the responses to high altitude. 6) Measure cardiac output and explain the physical laws and regulatory mechanisms governing the process. 7) Discuss the physiology of arteries, arterioles, capillaries and veins: regulation of vasomotor tone, rheological properties of blood and resistance to blood flow. 8) Explain the full physiological response to exercise including respiratory, vascular, cardiac and metabolic. 9) Measure respiratory, cardiovascular and metabolic responses to exercise and determine the anaerobic threshold non-invasively by graphical methods. 10) Apply fundamental physiological principles to solve problems derived from measurements made on healthy subjects and subjects with diseases selected to illustrate these principles. Problem solving Essay writing Laboratory measurement on human subjects Communication skills Group working skills 42 MODULE TITLE MODULE CODE SUMMARY CELLS AND TISSUES BMS2026 Year-2 Module Semester-1 (September -December) This module combines classical histology and cell biology with microscopy and tissue preparation methods. The module aims to provide students with an in-depth knowledge of mammalian cell and tissue architecture, the theory and practice of the main types of microscopy and the factors that control the visualisation of cells and tissues in vitro. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Clare Foy and Dr Joe Quinn LECTURES CONTACT TEACHING No 16 5 Total Hours 16 10 7 16 TUTORIALS PRACTICALS LEARNING OUTCOMES By the end of this module you will be able to: 1) Identify, describe and evaluate cell ultrastructure and function. 2) Distinguish between different tissues and organs based on their principal microanatomical features. 3) Outline how organs are made up of different tissues in varying proportions. 4) Suggest appropriate preparatory methods for a variety of microscopical techniques including fixation and staining methods. 5) Prepare a specimen for wax histology, including sectioning and staining. 6) Prepare a photographic record of the specimen in the form of a learning aid. 1) 2) 3) 4) 5) 6) SKILLS 7) 8) 9) 10) Critical analytical and problem-solving skills Safe handling of chemicals Use of laboratory instruments ensuring accuracy and reliability Scientific communication (oral and written skills) Collection, analysis and interpretation of micrographs Perform microscopy related technical skills in a competent manner (use of a microtome/ cryostat) Practical skills in working with routine histological stains. Ability to produce a laboratory notebook which is written in a clear, coherent and accurate manner. Specific IT skills required to photograph and digitally capture digital microanatomical images Micrograph analysis 43 MODULE TITLE MODULE CODE SUMMARY MOLECULAR CELL BIOLOGY BMS2015 Year-2 Module Semester-2 (February to May) This module covers the molecular basis of cell structure and function, including practical experience of handling and observing living mammalian cells. The module content covers fundamental issues such as plasma membrane structure and function, cellular compartmentalisation, mechanisms for protein and membrane-based transport between endomembrane compartments, organelle-specific functions, nuclear-cytoplasmic exchange, the cytoskeleton and cell junctions. Cell signalling mechanisms and the processes of information flow between the plasma membrane and the nucleus are covered in some detail and will provide students with the knowledge base to understand intracellular control mechanisms and the bulk of the literature published in current medical research. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr. William Allen LECTURES CONTACT TEACHING No 32 5 Total Hours 32 5 4 12 TUTORIALS (revision) PRACTICALS LEARNING OUTCOMES SKILLS By the end of this module you will be able to: 1. Classify the major intracellular compartments of eukaryotic cells and explain the mechanisms involved in the transport of biological molecules between them. 2. Relate cellular morphology and ultrastructure to differentiated function and gene expression. 3. Describe the major steps in the Biosecretory, Endocytic and Membrane Retrieval Pathways and explain the transport mechanisms involved throughout these pathways. 4. Discuss the functions of the lysosomal system and it’s relationships with the Biosecretory and Endocytic pathways. 5. Classify the elements of the cytoskeleton and explain their structural and dynamic functions in collaboration with associated motor proteins. 6. Differentiate the roles of major cell organelles. 7. Discuss the relationship between cells and their extracellular matrix. 8. Explain the principles of intercellular and intracellular communication. 9. Recognise the importance of post-translational modification in protein function, intracellular cell communication and maintenance of protein integrity. 10. Differentiate the major molecular mechanisms for the control of proliferation, survival and death in cells. 11. Discuss oxidative stress in cells and cellular defence strategies. 12. Outline the major experimental strategies employed in cell-based research. 1) 2) 3) 4) Searching scientific and literature databases. Critical reading of original scientific literature. Essay writing. Immunofluorescent staining, confocal scanning laser microscopy 44 MODULE TITLE MODULE CODE SUMMARY SCIENTIFIC METHODS AND STATISTICS BMS2014 Year-2 Module Semester-2 (February-May) Introduction to basic statistical principles/methods and experience in presenting, analysing and interpreting data. Experimental Design, Evaluation of Scientific Literature, Peer-Review and Scientific Writing & Experimental Models MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATORS Dr Chris Cardwell (Statistics) Dr Tom Gardiner (Scientific Methods) LECTURES CONTACT TEACHING LEARNING OUTCOMES No 20 9 Total Hours 20 9 PRACTICALS By the end of the Statistics component of this course you be able to: 1) Formulate research questions in testable statistical hypotheses. 2) Select and apply appropriate statistical methods for summarising data and for testing statistical hypotheses. 3) Perform statistical analyses using a computer package (Minitab) and interpret the output from such analyses. 4) Define the limitations of basic statistical methods. By the end of the Scientific Methods component of this module you will be able to: 1) Define and explain the different stages of the Scientific Method and the role of Inductive and Deductive Reasoning in its execution. 2) Define the major obstacles encountered in study design in the Biomedical Sciences and explain the use of experimental controls in overcoming such problems. 3) Design a controlled experiment to test a model hypothesis. 4) Describe the uses and limitations of the different types of experimental models in current Biomedical Research (in vitro, ex vivo & in vivo). 5) Define and explain the 3R-Principle in the ethical use of experimental animals. 6) Explain the role of non-hypothesis-driven research and the strategic use of gene expression profiling to inform conventional experimental approaches. 7) Describe the process of Peer-Review in the scientific community and apply the Scientific Method in the critical review of published research papers. 8) Describe the essential elements in writing a research grant and a paper for submission to a scientific journal. SKILLS 1) 2) 3) 4) Experimental design. Problem-solving and critical analysis of information. Practical use of Bibliographic Software (Refworks). Practical use of statistical software packages 45 MODULE TITLE MODULE CODE BRIEF SUMMARY TOPOGRAPHICAL ANATOMY-1 BMS2001 Year-2 Module Semester-2 (February-May) In this module students study the anatomy of the upper and lower limbs and thoracic cavity through structured self-directed learning. The major part of the module is in the weekly practical classes in which students carry out team-based investigative dissections of human cadavers. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Donal Shanahan LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS No 12 12 Total Hours 12 24 PRACTICALS On completion of this module you will be able to: 1) Describe the anatomy of the bones, muscles, joints, vasculature and innervation of the upper and lower limbs 2) Draw simple or schematic diagrams to illustrate basic anatomy 3) Use your knowledge of anatomy to discuss the functional anatomy of normal bodily or sporting movements performed by the limbs 4) Apply basic anatomical knowledge to solve problems in related fields such as clinical anatomy or human growth and development 5) Describe the development of the limbs 1) 2) 3) 4) 5) 6) 7) Learn professional behaviour and attitude in the handling of preserved human bodies Exercise safe practice in the dissecting room Obtain manual skills and an ability to use basic dissection instruments Develop three-dimensional visualisation and observational skills Develop ability to work effectively in a team Further develop your oral and written communication skills Learn to use reflective practice to strengthen and organise your learning. 46 MODULE TITLE EXERCISE AND APPLIED PHYSIOLOGY MODULE CODE BMS2008 SUMMARY MANAGING SCHOOL MODULE COORDINATOR Year-2 Module Semester-2 (February-May) In this module you will study the physiological responses of the human body to the challenge of exercise and the adaptations body systems make to deal with the increased physical demands. This knowledge of responses and adaptations is applied to clinical situations that either limit exercise (heart, respiratory and metabolic disease), or may be diagnosed using exercise tests. Human physiologic responses and adaptations to extreme environments (heat, cold, altitude) are also explored. Medicine Dentistry and Biomedical Sciences Dr Sean Roe LECTURES No 15 CONTACT TEACHING SEMINARS PRACTICALS LEARNING OUTCOMES Total Hours 23 3 9 6 12 By the end of this module you will be able to: 1. Describe how the increased metabolic demands of exercise are met by changes in the cardiovascular, respiratory and musculoskeletal systems. 2. List the modalities of fitness and explain how they are affected by training. 3. Apply your knowledge of the responses and adaptations to exercise to the diagnosis of common clinical syndromes (heart and lung pathologies) 4. Discuss how disease processes limit exercise. 5. Explain the adaptations the body makes in coping with the extreme environments of excessive heat, cold and high altitude 6. Measure strength, explosive power, endurance, flexibility and anthropomorphic data in your class colleagues. 7. Analyse the exercise literature and present data to your colleagues This course will give you the opportunity to develop the following skills: SKILLS Written communication Group work Communication skills Oral presentation using presentation software Measurement of human exercise and anthropomorphic data both in a basic physiology laboratory and a dedicated human performance suite. Data manipulation, graphical representation and display using spreadsheet software 47 MODULE TITLE HUMAN PHYSIOLOGICAL MEASUREMENT MODULE CODE BMS2028 SUMMARY MANAGING SCHOOL MODULE COORDINATOR Year-2 Module Semester-2 (February-May) An intermediate level study of the physiology and pathophysiology of the cardiovascular, respiratory and neurological systems and exercise performance of the human body combined with study of the methods used to assess their function in clinical and research settings. Medicine Dentistry and Biomedical Sciences Dr Chris Johnson LECTURES No 18 CONTACT TEACHING LEARNING OUTCOMES TUTORIALS 1 Total Hours 18 3 7 14 PRACTICALS By the end of this module you should be able to: 1) Describe the normal physiology of the cardiovascular, respiratory and central nervous systems and the pathophysiological changes associated with the major diseases that commonly affect these systems. 2) Perform a range of physiological tests important in the clinical evaluation of the cardiovascular, respiratory and central nervous systems and interpret the results. 3) Explain the basic physiological determinants of human performance: 4) Describe the limitations to aerobic and anaerobic performance and be able to describe and perform tests to measure such performance parameters. This course will give you the opportunity to develop the following skills: SKILLS Problem solving Experimental design and procedures for physiological studies in human subjects Collection and processing of experimental data Data interpretation 48 MODULE TITLE MODULE CODE BRIEF SUMMARY DIET & HEALTH ALU2008 Year-2 Module Semester-2 (February-May) DIET AND LIFESTYLE: Vegetarians and vegans; Nutrition for exercise and sport; Alcohol and diet; Functional Foods; Diet and Health Promotion: Healthy Eating, nutritional labelling, dietary targets, achieving dietary change. NUTRITIONAL EPIDEMIOLOGICAL STUDIES. DIET AND METABOLIC SYNDROME: Obesity; Diabetes; Dislipidaemia. DIET AND DISEASE: Mechanisms of effect and dietary constituents of interest; Diet and Cancer; Cardiovascular disease - hypertension and salt intake, influence of B vitamins; Bone health; Food allergies and tolerances - immune function. MANAGING SCHOOL Biological Sciences MODULE COORDINATOR Dr Geraldine Cuskelly LECTURES CONTACT TEACHING No 12 4 Total Hours 12 15 3 7 PRACTICALS TUTORIALS Students will gain a knowledge of the inter-relationships of diet and health. LEARNING OUTCOMES SKILLS Assimilation of knowledge; group working skills; literature reviewing; data retrieval, interpretation and presentation; practical laboratory skills; written and oral communication skills. 49 MODULE TITLE MODULE CODE BRIEF SUMMARY TOPOGRAPHICAL ANATOMY-2 BMS3011 Year-3 Module Semester-1 (September-December) This module takes a detailed systematic, cadaveric, dissection-based approach to study the normal anatomy of the head, neck, vertebral column, abdomen and pelvis. Included with this, is the major structures of the central- and peripheral nervous systems. Clinical applications are discussed where relevant. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Donal Shanahan LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS No 12 12 Total Hours 12 36 PRACTICALS On completion of this module you will be able to: 1) Summarise the inter-relationship of the body systems covered in the module. 2) Provide detailed verbal and written descriptions of the structures and systems studied, with correct use of anatomical nomenclature and suggestions for clinical application. 3) Isolate nerve and vascular tracts in situ and identify their origins and functions in each off the systems studied. 4) Describe the dynamic functions of musculoskeletal relationships encountered in these systems. 1) 2) 3) 4) 5) 6) Team working skills Oral presentation skills Fine manual dissection skills Observational skills Writing skills General IT skills 50 MODULE TITLE MODULE CODE BRIEF SUMMARY MANAGING SCHOOL MODULE COORDINATOR DEVELOPMENTAL STUDIES BMS3003 LEARNING OUTCOMES SKILLS Semester-1 (September-December) This course exploits the knowledge-base of developmental biology to provide students with concepts and mechanistic understanding of stem cell biology and how it may be exploited for regenerative medicine. Concepts of cell fate determination and pattern formation mediated by a limited repertoire of diffusible and contact-mediated morphogens are illustrated and developed through study of the basic processes of gastrulation, neurulation and tissue cross-talk in the development of a complex organ (the eye). The role of genetic hierarchies is illustrated through study of the HOX genes in body plans and haematopoiesis and the epigenetic basis of cellular differentiation is presented as stepwise alterations in gene expression profiles with cell and tissue-specific differences attributable to differential gene silencing or enhancement. The role of traditional and conditional transgenic approaches in determination of basic mechanisms and the role of individual genes in development is studied. Medicine Dentistry and Biomedical Sciences Dr William Allen LECTURES CONTACT TEACHING Year-3 Module No 13 10 Total Hours 13 10 TUTORIALS On completion of this module you will be able to: 1) Summarise the principles of tissue cross-talk in development, including the concepts of induction, competence, differentiation and lateral inhibition in cell fate determination and tissue patterning. 2) Discuss the importance of asymmetric division in development and parenchymal cell generation from tissue-specific stem cells in adulthood 3) Describe the role of HOX genes as master control genes in the orchestration of genetic hierarchies in animal development and cell fate determination. 4) Describe the interaction of DNA methylation, post-translational histone modification and chromatin remodelling in the epigenetic control of cell fate determination. 5) List the different sources of stem cells that may be used for novel therapeutic approaches in regenerative medicine and discuss the practical and ethical advantages or disadvantages encountered with each. 6) Discuss epigenetic reprogramming in normal development and the challenge of such reprogramming in the induction of pluripotency in differentiated cells. 7) Describe how gene deletion may be accomplished in the germ line or in a tissuespecific manner in adulthood. On completion of this course students will have gained or increased competence in: 1) Critical, analytical and creative thinking 2) Problem solving abilities 3) General IT skills 4) Online literature searching 5) Scientific writing skills 51 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR SCIENTIFIC LITERATURE PROJECT BMS3015 Year-3 Module Semester-1 (September-December) In this module students will be required to carry out an extensive review of the scientific literature in order to answer a question of relevance to biomedical or Human Biology research. They will have to produce a dissertation of approximately 10,000 words reflecting the student’s personal studies in the literature, a description of the background to the question posed followed by critical discussion and conclusions. The student will also have to give a 10 minute oral presentation (followed by 5 minutes of questions) of their dissertation material. Medicine Dentistry and Biomedical Sciences Dr William Allen SELF-DIRECTED LEARNING No CONTACT TEACHING TUTORIALS 2 By the end of this module you will be able to: Total Hours 180 2 1) Undertake literature based research under appropriate supervision. LEARNING OUTCOMES 2) Critically evaluate the literature in the field. 3) Discuss subject specific knowledge in a specialised are of current Biomedical / Human Biology research SKILLS On completion of this course successful students will have gained or increased competence in: 1) Critical, analytical and creative thinking 2) Data–base interrogation 3) Data management skills 4) Use of bibliographic software 5) Organisational skills 6) General IT skills 7) Time management skills 52 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR RESEARCH PROJECT AND THESIS BMS3012 Year-3 Module Semester-1 (September-December) This double-module provides students with the opportunity to undertake a substantial piece of independent research and to further develop their capacity for independent, analytical and critical thought and technical/transferable skills. Medicine Dentistry and Biomedical Sciences Dr William Allen SELF-DIRECTED LEARNING No CONTACT TEACHING TUTORIALS 2 By the end of this module you will be able to: LEARNING OUTCOMES Total Hours 180 2 On completion of this module successful students will be able to: 1) Demonstrate competence in estimation of the resources required to undertake a project (e.g. material, financial, time, personal). 2) Formulate clear action plans to deal with the work in an efficient manner including, where appropriate, the preparation of an application for ethical approval. 3) Prepare a COSHH risk assessment and hazard identification of all the chemicals and procedures entailed in their project. 4) Demonstrate safe working practices in the laboratory and be aware of their responsibilities with regard to their own health and safety and that of other users of the laboratory. 5) Demonstrate effective time-management skills, including punctuality in the meeting of deadlines (e.g. supervisory meetings, interim reports, final write-up etc.). 6) Demonstrate an appreciation of the requirements, for obtaining accurate and valid scientific data through presentation of clear records in a well-kept laboratory notebook. 7) Demonstrate a critical appreciation of the limits and significance of scientific findings as evidenced in their interim reports, thesis and oral presentation. On completion of this course successful students will have gained or increased competence in: SKILLS 1) 2) 3) 4) 5) 6) 7) Critical, analytical and creative thinking Practical laboratory skills Problem solving abilities General IT skills Online literature and scientific database searching Scientific writing skills Oral communication skills 53 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR CONTACT TEACHING LEARNING OUTCOMES SKILLS CELLULAR AND MOLECULAR HAEMATOLOGY BMS3009 Year-3 Module Semester-1 (September-December) The course will cover the following topics. Haemoglobin and defects in haemoglobin synthesis; the molecular basis of anaemia; haematopoietic growth factors; signal transduction and cell cycle regulation in normal haematopoiesis and in haematological disorders; myeloproliferative disorders; lymphoma; the cellular and molecular basis of haemostasis and thrombosis and the role of HOX genes and epigenetic mechanisms in haematopoiesis and leukaemogenesis. Medicine Dentistry and Biomedical Sciences Professor Ken Mills LECTURES No 21 Total Hours 21 TUTORIALS 2 2 PRACTICALS 12 12 By the end of this module you will be able to: 1. Summarise the cellular and molecular bases of modern research in haematology. 2. Discuss how the study of haemoglobin has paved the way for the development of molecular medicine. 3. Summarise how defects in cellular and molecular processes can lead to haematological disorders. 4. Evaluate how current research may lead to a better understanding of normal and abnormal blood cell function and the rational design of molecular therapeutic strategies. 5. Discuss trends in drug design and other therapeutic approaches in leukaemia. This module will exercise and further develop the following skills: 1. Critical thinking 2. Self-directed learning 3. Literature searching 4. IT skills 5. Oral and written communication 54 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR CONTACT TEACHING LEARNING OUTCOMES SKILLS MOLECULAR PHARMACOLOGY TPU3001 Year-3 Module Semester-1 (September-December) The course will cover neurotransmitters, peptides, eicosanoids and nitric oxide as chemical mediators including some aspects of receptor biology and signal transduction as a basis for understanding drug action and novel therapeutic strategies. The quantitative analysis of drug-receptor interactions and the principles of immunopharmacology are also covered. Medicine Dentistry and Biomedical Sciences Dr David Bell LECTURES No 30 Total Hours 30 TUTORIALS & 6 6 SEMINARS 8 8 By the end of this module you will be able to: 1) Compare and contrast the properties of neurotransmitters, bioactive peptides, eicosanoids, inflammatory mediators and nitric oxide 2) Discuss the central role of the receptor as the site of action of many drugs and endogenous chemical mediators 3) Explain the fundamental differences between the four main classes of receptor protein in regard to molecular structure and receptor-effector coupling mechanism 4) Describe signal transduction through G-proteins, ion channels, second messenger substances and kinases with emphasis on specificity and diversity within cell signalling offering opportunity for selective intervention 5) Analyse, represent graphically, and interpret drug concentration-response data 6) Describe the principles of radioligand binding, analyse, represent graphically, and interpret drug radioligand binding data 7) Discuss which cells and mediators are key in the development of inflammation 8) Describe the mechanism of action of drugs used to control the inflammatory response, with particular emphasis on the therapeutic management of asthma On completion of this course successful students will have gained or increased competence in: 1) Critical, analytical and creative thinking 2) Problem solving abilities 3) General IT skills 4) Online literature searching 5) Scientific writing skills 6) Statistical analysis and graphical presentation of data 7) Oral and poster presentation skills 8) Team-working 55 MODULE TITLE MODULE CODE BRIEF SUMMARY SCIENCE IN EDUCATION EDU3009 Year-3 Module Semester-2 (February-May) This module will offer, through university-based workshops and school-based observation, a ‘taster’ for those committed to or thinking about teaching as a career. It is also relevant to students, whatever their eventual career choice, who are interested more widely in science communication and the public engagement with science. The workshops deal with topics such as the nature of science, why science learning is important, the school science curriculum and how science can be communicated in interesting and accessible ways in both formal and informal settings. The sessions will be highly interactive, illustrating approaches which are being adopted increasingly in science education. These issues will be contextualised through a programme of school (or other) visits. Assessment will involve the writing of an essay or report and the preparation and presentation of resource materials for teaching science. Those interested in applying should note that an enhanced disclosure check by Access NI must be undertaken prior to the school (or other) visits and students will need to familiarise themselves with and abide by the QUB Code of Conduct. MANAGING SCHOOL School of Education MODULE COORDINATOR Dr Ruth Jarman 56 MODULE TITLE MODULE CODE BRIEF SUMMARY CLINICAL NUTRITION SCM3001 Year-3 Module The aim of this module is to help students develop an understanding of the role of nutrition in the treatment and management of a range of diseases and disorders. It covers topics such as: cardiovascular disease, diabetes, obesity, malnutrition, inflammatory bowel disease, coeliac disease, cystic fibrosis, cancer, burns and wound healing and eating disorders. MANAGING SCHOOL School of Biological Sciences MODULE COORDINATOR Dr Michelle McKinley LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS Semester-2 (February-May) No 18 4 Total Hours 18 4 PRACTICALS On completion of this module you will be able to: - Describe the role of nutrition in the treatment and management of a number of diseases. - Discuss the role of nutritional support in clinical practice On completion of this course it is expected that the student will be able to Distinguish between nutritional requirements in health and disease/illness. Search the scientific literature and retrieve relevant information on a particular area of nutrition science. Critically assess and evaluate scientific literature in relation to a particular area of nutrition science. Demonstrate the ability to follow a specific scientific referencing format Demonstrate proficiency in written communication skills. Evaluate information on diet and nutritional status in order to make suggestions for improvements, in line with clinical guidelines for a particular condition Demonstrate the ability to manipulate and interpret nutrition-related data Attitudes: Assume responsibility for their own learning. Plan and prioritise their workload in order to meet deadlines Data manipulation and interpretation, retrieval of scientific information, critical analysis of scientific literature, evaluation of information on diet and nutritional status, written communication skills, time management skills 57 MODULE TITLE MODULE CODE BRIEF SUMMARY TISSUE BIOLOGY & PATHOLOGY BMS3024 Year-3 Module Semester-2 (February-May) This module aims to extend the perspective gained through student’s study of Molecular Cell Biology to the tissue level, thus introducing them to molecular histology The four main tissue types are covered but the focus in each is on the structural components of cells that characterise whole tissues and how such elements are affected by disease and its treatment. The bulk of the teaching in the module is carried out by the students working in groups under direction of staff facilitators. The core study topics focus on genetic and autoimmune diseases affecting muscle, epithelium and connective tissue, neurodegenerative disease and cancer. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr Eilish Donnelly LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS No 10 10 Total Hours 10 12 TUTORIALS 4 12 PRACTICALS On completion of this module you will be able to: 1) Discuss the ultrastructural elements common to all cells and tissues in relation to their cell and tissue-specific roles. 2) Discuss the cytoskeleton, cell junctions, and organelles in terms of their cell, tissue and organ-specific functions, and their constituent proteins using molecular models. 3) Discuss cell and matrix proteins as products and targets of disease. 4) Devise protocols with appropriate controls for experiments or problems involving in situ methods for the microscopic localisation of specific gene products, both message and protein. 1. 2. 3. 4. 5. Problem solving and critical analysis of information Use of online data bases Team working Time management and prioritisation of tasks Preparation and delivery of oral presentations using Microsoft PowerPoint. 58 MODULE TITLE MODULE CODE BRIEF SUMMARY MANAGING SCHOOL MODULE CO-ORDINATOR INFECTIONS VMI3005 Year-3 Module Semester-2 (February-May) The requirements for a successful pathogenic microbial existence will be considered in the context of the epidemiology and spread of infection, the molecular basis of virulence and the pathogenesis of disease. Biological/Biomedical Sciences To be confirmed No 33 Total Hours 33 LECTURES CONTACT TEACHING METHODS/HOURS TUTORIALS PRACTICALS OTHER (please indicate) On completion of the module students will be able to: LEARNING OUTCOMES SKILLS (1) Discuss the nature of microbial virulence at the molecular level (2) Discuss the pathogenesis, epidemiology and control of selected infectious diseases (3) Evaluate the research literature relevant to the module (4) Discuss the genetic mechanisms responsible for antibiotic resistance The development of conceptual thinking and an understanding of the scientific process. Key transferable skills include: Essay writing, extracting information from multimedia sources, accuracy/thoroughness, familiarity with IT, time management, planning tasks, presenting a reasoned argument 59 MODULE TITLE MODULE CODE BRIEF SUMMARY NEUROSCIENCE BMS3002 Year-3 Module Semester-2 (February-May) This course provides an overview of the functional organisation of the Central Nervous System: cortical and subcortical elements and the cerebellum. The cell biology of the neurones and glia and their roles in normal synaptic transmission and the common mechanisms of neuropathology such as neurodegeneration, demyelination and glial scarring are also covered as a basis of more focussed studies of specific CNS diseases. Likewise the cell biology of the Blood-Brain Barrier and the normal physiology of the NeuroVascular Unit are described and discussed in relation to CNS inflammation and disease mechanisms. Several topics are dealt with at a more specialised level: Nociceptive pain mechanisms and pathways, retinal photoreception and visual processing, neurodegenerative disease and regeneration. MANAGING SCHOOL Medicine Dentistry and Biomedical Sciences MODULE COORDINATOR Dr A Al-Modhefer LECTURES CONTACT TEACHING LEARNING OUTCOMES SKILLS No 10 4 Total Hours 20 14 SEMINARS On completion of this module you will be able to: 1) Interpret and critically evaluate research literature in the field of neuroscience 2) Discuss the specialised functions of the central nervous system at a cellular and gross organisational level 3) Summarise the common responses of the CNS to inflammation and disease 4) Outline the cellular and molecular mechanisms that produce and maintain the bloodbrain barrier and propose strategies to overcome the therapeutic challenges imposed by the barrier in the treatment of disease 5) Summarise and discuss the mechanisms and pathways of nociceptive pain and retinal photoreception and visual processing. 6) Compare and contrast the major neurodegenerative diseases, identify their common molecular pathological mechanisms and evaluate the putative treatment strategies suggested by such mechanisms On completion of this course successful students will have gained or increased competence in: 1) Critical, analytical and creative thinking 2) Problem solving abilities 3) General IT skills 4) Online literature searching 5) Written and oral presentation skills 60 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR CONTACT TEACHING LEARNING OUTCOMES SKILLS CARDIOVASCULAR PHARMACOLOGY TPU3006 Year-3 Module Semester-2 (February-May) Topics include the pathophysiology underpinning diseases of the cardiovascular system (hypertension; heart failure; ischaemic heart disease manifest as angina pectoris and acute coronary syndromes; cardiac dysrhythmias; endothelial dysfunction and atherosclerosis; thromboembolism and coagulation disorders; stroke); experimental approaches in cardiovascular research; design of clinical trials in cardiovascular disease; diagnostic applications of cardiovascular biomarkers; clinical pharmacology (action, uses and side effects) of: alpha and beta adrenoceptor antagonists; inhibitors of the renin-angiotension system; calcium channel modulators; organic nitrates; positive inotropic drugs; diuretics; anti-arrhythmic agents; anti coagulants; fibrinolytics and anti-platelet drugs; lipid-regulating agents. Medicine Dentistry and Biomedical Sciences Dr David Bell LECTURES No 25 Total Hours 25 TUTORIALS & 2 2 SEMINARS 5 5 By the end of this module you will be able to: 1) Discuss the pathophysiological mechanisms underpinning common diseases of the heart and vasculature including: hypertension; atherosclerosis; thrombo-embolism; coronary artery disease, stable angina and acute coronary syndromes; cardiac arrhythmias; chronic heart failure 2) Describe the mechanisms of action, main clinical uses and important adverse effects and contra-indications of the following classes of drugs: alpha and beta blockers; modulators of the renin angiotensin system; calcium channel modulators; nitrates; positive inotropic drugs; diuretics; anti-arrhythmic drugs; anti-platelet agents and anti-coagulants; fibrinolytics; lipidregulating drugs; anti-diabetic drugs 3) Critically evaluate clinical trials designed to investigate the effectiveness of specific drugs in various patient groups 4) Discuss current guidelines for the management of hypertension, dyslipidaemia, angina, acute coronary syndrome, heart failure, atrial fibrillation 5) Assess the rationale for development of novel therapies to prevent or treat cardiovascular diseases On completion of this course successful students will have gained or increased competence in: 1) Critical, analytical and creative thinking 2) Problem solving abilities 3) General IT skills 4) Online literature searching 5) Scientific writing skills 6) Oral presentation skills 7) Team-working 61 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR CONTACT TEACHING LEARNING OUTCOMES SKILLS INTEGRATED PHARMACOLOGY TPU3008 Year-3 Module Semester-2 (February-May) The course will cover the principles of pharmacokinetics, the drug development process and design of clinical trials, pharmacoeconomics, drug interactions and adverse drug reactions, pharmacogenomics, treatment of poisoning and toxicology. Also covered are drug prescribing at extremes of age, in pregnancy and in liver or kidney disease. Finally the clinical pharmacology of drugs targeting major organ systems will focus on diseases of the gastrointestinal tract and musculo-skeletal system. Medicine Dentistry and Biomedical Sciences Dr David Bell LECTURES No 26 Total Hours 26 TUTORIALS & 2 2 SEMINARS 2 4 By the end of this module you will be able to: 1) Describe the processes involved in drug discovery and development 2) Describe and critically appraise the design of clinical trials 3) Evaluate drug marketing literature and discuss post marketing surveillance of drug safety 4) Describe processes involved in drug absorption, distribution, metabolism and excretion 5) Analyse pharmacokinetic data and apply pharmacokinetic principles to special patient populations including children, the elderly and those with liver or kidney disease 6) Discuss the mechanistic basis of adverse drug reactions and drug interactions 7) List common toxins and describe their mechanisms of action, effects on the body and strategies for the treatment of poisoning 8) Describe the mechanisms of action of performance-enhancing drugs, drug testing and potential for misuse of drugs in sport 9) Discuss current knowledge concerning the mechanisms of action, and consideration of the potential therapeutic applications and possible adverse effects of herbal medicines 10) Describe the pathophysiology of diseases of the musculoskeletal system and evaluate novel therapeutic approaches to the treatment of diseases such as osteoporosis and rheumatoid arthritis 11) Describe the pathophysiology of diseases of the gastrointestinal system and evaluate novel therapeutic approaches to the treatment of diseases such as peptic ulcer, inflammatory bowel disease, nausea and vomiting. 1)Critical, analytical and creative thinking 2)Problem solving abilities 3)General IT skills 4)Online literature searching 5)Scientific writing skills 6)Analysis and graphical presentation of pharmacokinetic data 7)Oral and poster presentation skills 62 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR VASCULAR BIOLOGY BMS3027 Dr Denise McDonald & Dr Tom Gardiner LECTURES SKILLS Semester-2 (February-May) The module covers the rapidly developing area of angiogenesis research. Vasculogenic and angiogenic mechanisms of vascular development will be covered at the cell and molecular level and the role of endothelial progenitor cells (EPCs) in vascular development and repair in adulthood will be discussed; possible uses of EPCs in therapeutic angiogenesis as a treatment modality following ischaemic disease insults will also be explored. The eye as a model and target of neovascular disease will be studied in detail as the juxtaposition of highly vascularised and avascular tissues in this organ provides unique pathology, opportunities for exploitation in model systems and novel therapeutic approaches. Physiological and pathological angiogenesis will be compared in detail during normal retinal vascular development and pathological neovascularisation, also in the development of solid tumours and wound healing responses. Current models employed in angiogenesis research will be examined. Medicine Dentistry and Biomedical Sciences CONTACT TEACHING LEARNING OUTCOMES Year-3 Module No 12 Total Hours 12 TUTORIALS 10 10 By the end of this module you will be able to: 1) Compare the major features of angiogenesis and vasculogenesis in development. 2) Compare hypoxia and inflammation as the major biological imperatives driving angiogenesis. 3) Discuss oxygen sensing at the molecular level and its relationship to the control of angiogenesis. 4) Summarise the signalling mechanisms driving angiogenesis during hypoxia and inflammation. 5) Discuss the physiological and pathophysiological roles of nitric oxide in the microvasculature. 6) Compare and contrast the 3 major neovascular diseases of the retina. 7) Discuss the sources of endothelial progenitor cells (EPCs) and their roles in vascular development and repair in adulthood. 8) Discuss the role and molecular mechanisms of avascularity in specialised tissues such as cornea and cartilage. 9) Discuss angiogenesis in solid tumours in relation to stages in tumour development and the unique metabolism of cancer cells. 10) Summarise current strategies for anti-angiogenic treatment of cancer and neovascular disease and therapeutic angiogenesis following tissue ischaemia. Critical, problem solving skills, analytical and creative thinking Critical review of the scientific literature Oral presentation skills Online literature searching Team working 63 MODULE TITLE MODULE CODE SUMMARY MANAGING SCHOOL MODULE COORDINATOR ADVANCED CARDIOVASCULAR PHYSIOLOGY BMS3005 LEARNING OUTCOMES SKILLS Semester-2 (February-May) The module seeks to introduce students to advanced study of the cardiovascular system through weekly student-led oral presentations of current and classic research papers from the field. Study areas include capillary fluid exchange, microvascular specialisation, endothelial regulation, lymphatic function, the peripheral circulation in humans, and electrical activity and regulation of the cardiovascular system. Medicine Dentistry and Biomedical Sciences Dr Tim Curtis LECTURES CONTACT TEACHING Year-3 Module No 6 Total Hours 6 SEMINARS 12 48 By the end of this module you will be able to: 1. Critically evaluate research papers in the field of cardiovascular physiology and pathophysiology 2. Evaluate research techniques in cardiovascular physiology. 3. Apply physiological principles to research in cardiovascular physiology 4. Compare intrinsic (local) and extrinsic mechanisms controlling vascular function 5. Summarise and propose a functional rationale for the phenotypic modification and regulatory mechanisms of the vasculature in specialised tissues/organs On completion of this course successful students will have gained or increased competence in: Critical, analytical and creative thinking Problem solving abilities General IT skills Oral presentation Peer-teaching Self-directed learning 64 UNIVERSITY INFORMATION LIBRARIES AND OPENING TIMES The main libraries containing information applicable to Biomedical Science and Human Biology students are the Biomedical Library (Ground Floor, Medical Biology Centre), the Medical Library (Mulhouse Building, Royal Victoria Hospital) and The McClay Library (College Park). Library opening times can be accessed via the following link: http://www.qub.ac.uk/directorates/InformationServices/TheLibrary/LibraryOpeningHours/ Information on all Queen's Medical and Healthcare libraries is available from the following link: http://www.qub.ac.uk/directorates/InformationServices/TheLibrary/BiomedicalLibrary/AboutTh eBiomedicalLibrary/ SUPPORT FOR STUDENTS AT QUEEN’S Introduction The University takes the view that all aspects of student life offer opportunities for learning and development. Schools work closely with student support services and the Students’ Union to support your personal development planning, providing a range of academic and personal support services and developmental opportunities during your time at Queen’s. Support and development opportunities for students are offered through your academic School, as well as centrally in the Student Guidance Centre, International and Postgraduate Student Centre and the Students’ Union. If you are not sure where to go when you have a question about any element of University life, ask one of the Information Assistants in the Student Guidance Centre or International and Postgraduate Student Centre. Starting University Moving to higher education is an exciting time and a new phase in your life. Whilst you may have been looking forward to it for some time, don’t be surprised if you find it overwhelming at times – it’s normal to feel this way. For those of you who have recently left compulsory education, studying for a degree is very different. You have much more freedom to decide what you want to learn, and you will be asked to consider and debate about the content of your course. You will be expected to be more self-directed in how you approach your studies. Unlike school, your lecturers and Advisor of Studies will guide you but will not direct you as much as your teachers may have done in the past. Information about making a successful transition to higher education can be found at: www.qub.ac.uk/welcome. Within your academic School, you can discuss any issues that arise and receive guidance on approaching new situations from Academic Advisers to Research Mentors. Health and Safety For your information, there are 2 defibrillators in the MBC – one is with the porter at MBC reception and the other is outside the old nursing reception, Ground Floor, South Side, MBC. There is no training required on how to use the defibrillator. The University has an obligation to provide a safe environment whilst studying here. You may be exposed to some potentially hazardous situations, particularly in the laboratory environment. Our Centre complies with the Universities requirements to ensure your safety. The University safety guidance is available from the University occupational health web site, along with contacts for any other personal health issues: http://www.qub.ac.uk/directorates/HumanResources/OccupationalHealthandSafety/ There are also local safety rules that apply to different areas within our Centre (for example, physiology teaching labs, histology teaching lab and dissection room). These are posted in each area, and are included in relevant study guides. They are also available in a Centre safety handbook, which is available 65 on request from our Centre office. This guidance is there for your own safety, so please, make yourself familiar with it before attending the relevant class/practical. University Support Specialist support services are offered through both the University’s Student Guidance Centre and the Students’ Union. The Student Guidance Centre and the Students’ Union work closely together to provide comprehensive services. The Students’ Union is located on University Road, opposite the Lanyon Building. The Student Guidance Centre is also on University Road, above the Ulster Bank, and the Post Office. The Student Guidance Centre University Terrace Tel: 028 9097 2727 Email: sgc@qub.ac.uk Website: www.qub.ac.uk/sgc/ The Queen’s University Students’ Union University Road Tel: 028 9097 3726 Email: studentsunion@qub.ac.uk Website: www.qubsu.org The International Student Support Centre International and Postgraduate Student Centre Tel: 028 9097 3899 Email: internationalstudentsupport@qub.ac.uk The Postgraduate Centre International and Postgraduate Student Centre Tel: 028 9097 2585 Email: pg.office@qub.ac.uk The McClay Library 10 College Park Tel: 028 9097 6135 Website: http://www.qub.ac.uk/directorates/InformationServices/TheLibrary/ What follows is a brief summary of the range of support that is available. Details about service access and offerings are available on-line, and accessible to students through the Student Gateway website: www.qub.ac.uk/studentinfo If you are not sure which service is most appropriate, call the Student Guidance Centre on 028 9097 2727 and one of the Information Assistants will point you in the right direction. • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • PDP Accommodation. Careers and Employability Degree Plus Paid employment during the academic year Chaplaincy Counselling Students with disabilities Finance Health Centre Learning Development Service Library Queen’s sport (PEC) Scholarships and Prizes Study Abroad/ERASMUS Study support Student Guidance Centre Students’ Union Student Computing Centres International students Postgraduate Centre Postgraduate Funding Languages for Non-Specialists Health and Safety School support mechanisms Qsis and QOL Mature and part-time students Childcare Students Intervention Protocol Change of address/details Anti-bullying and Harassment Policy Starting University Students with Experience of Care 66 Support and advice for students on the following issues can be found at: http://www.qub.ac.uk/home/TheUniversity/GeneralServices/Informationfor/Students/StudentGuidance/Thin gsnotgoingtoplan/ • • • • • • • • • Absence from Study Changing your Course Temporary Withdrawal Withdrawal from the University Exceptional circumstances Student Support Meetings Academic Appeals Student Complaints Procedure Procedures for Dealing with Academic Offences DISCLAIMER This handbook is intended as a guide for students on the Biomedical Science, and Human Biology degrees and is intended to supplement School and University publications and not replace them. 67