Summer School on Infection Research June 22-27, 2014 Dresden Sunday, June 22, 2014 15:00-16:30 Registration & Check-In 17:00 Reception Welcome Addresses 17:20 D. Heinz Scientific director HZI, Executive Board DZIF 17:25 N. Löchte Referentin Impuls- und Vernetzungsfonds, Helmholtz Association, Berlin Introduction of the kick off lecturer: 17:30 Kick off lecture G. Krause, Head of the Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig “The German National Cohort – a novel research opportunity for infectious disease research“ 18:30 Dinner 20:00 Speed dating - wine and cheese – Art Foyer Monday, June 23, 2014 07:00-09:00 Breakfast Session I: Immunity Chair: H. Hauser. 09:00 M. Flajnik, University of Maryland, Baltimore General lecture: Evolution of antigen receptors in vertebrates 09:30 T. Eigenbrod, University of Heidelberg General lecture: Innate Immunity 10:00 D. Busch, Technical University of Munich General lecture: Tcell differentiation 10:30 F. Förster, Hannover Medical School General lecture: Development of secondary and tertiary lymphoid organs 11:00-11:30 Coffee break Chair: H. Hauser 11:30 M. Flajnik, University of Maryland, Baltimore Special lecture: Ontogeny and phylogeny of lymphoid tissues 12:00 C. Watzl, Leibniz Research Centre for Working Environment and Human Factors, Dortmund Special lecture: How to stick, kill and let go without getting hurt – daily problems of a Natural Killer 12:30 F. Förster, Hannover Medical School Special lecture: Killing of cytotoxic T cells in vivo 13:00-14:30 Lunch time in tutor groups Monday, June 23, 2014 Chair: V. Wray 14:30 T. Eigenbrod, University of Heidelberg Special lecture: Recognition of bacterial RNA by the innate immune system 15:00 D. Busch, Technical University of Munich Special lecture: Single T cell fate tracking and its implications for immunotherapy 16:00 Guided sight-seeing tour to Dresden Dinner in Restaurant Sophienkeller Tuesday, June 24, 2014 07:00-09:00 Breakfast Session II: Viruses Chair: H. Hauser 09:15 J. Yewdell, National Institute of Allergy and Infectious Diseases, Bethesda General lecture: Why you should become a viral immunologist 09:45 F. Kirchhoff, Universitätsklinikum Ulm General lecture: Adaptations facilitating the AIDS pandemic 10:15 A. Garcia-Sastre, Mount Sinai School of Medicine, New York General lecture: Influenza virus, host tropism and virulence 10:30-11:00 Coffee break Chair: M. Stadler 11:00 L. Babiuk, University of Alberta N.N. lecture: Improving human and animal health through vaccination: Global health and economic implications 11:45 U. Protzer, Technical University of Munich Special lecture: Can we cure HBV infection? 12:15 F. Kirchhoff, Universitätsklinikum Ulm Special lecture: A possible gatekeeper for CXCR4-tropic HIV-1 strains 12:30-15:00 Lunch break Tuesday, June 24, 2014 Chair: H.Hauser 15:00 J. Yewdell, National Institute of Allergy and Infectious Diseases, Bethesda Special lecture: Why does flu drift? 15:30 A. Garcia-Sastre, Mount Sinai School of Medicine, New York Special lecture: TRIMmunity: The roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity 16:00-16:30 Coffee Break Chair: H. Hauser 16:30 Key note lecture H. zur Hausen, German Cancer Research Center, Heidelberg „Mechanisms of cancer developments linked to infections“ 18:00 Dinner 20:00-23:00 Poster session – wine and cheese Wednesday, June 25, 2014 07:00-09:00 Breakfast Session III: Antiinfectives and vaccines Chair: V. Wray 09:00 P. Selzer, MSD Animal Health Innovation GmbH, Schwabenheim Special lecture: Protein Kinases as Suitable Targets for Combating Coccidiosis 09:30 K. Cichutek, Paul-Ehrlich-Institute, Langen Special lecture: Using measles virus in biomedicine: oncolytic virus and cell targeting vectors 10:00 M. Stadler, Helmholtz Centre for Infection Research, Braunschweig Special lecture: Translating fungal biodiversity into novel antiinfectives and other secondary metabolites with practical utility 10:30 H.-G. Sahl, University of Bonn Special lecture: (tbc) 11:00-11:30 Coffee Break Chair: S. Kirchhoff 11:30 Short presentation PhD1 11:45 Short presentation PhD2 12:00 Short presentation PhD3 12:15 Short presentation PhD4 12:30-13:30 Lunch break 13:45 19:05 Departure excursion to Pillnitz Arrival Dresden Free evening Thursday, June 26, 2014 07:00-09:00 Breakfast Session IV: Parasites Chair: N.N. 09:00 C. Bogdan, University Clinic of Erlangen General lecture: Leishmania (tbc) 09:30 M. Engstler, University of Würzburg General lecture: Trypanosome immune escape 09:45 C. Caffrey, University of California San Francisco General lecture: Cysteine proteases as drug targets for new antiparasitics 10:15-10:45 Coffee break Chair: N.N. 10:45 C. Bogdan, University Clinic of Erlangen Special lecture: tba 11:15 M. Engstler, University of Würzburg Special lecture: Trypanosome physics 11:45 C. Caffrey, University of California San Francisco Special lecture: Helminth diseases: strategies and technologies for drug discovery and development 12:15 A. Müller, University of Heidelberg Special lecture: Plasmodium attenuation at the liver stage: Connecting the dots between sterile protection and alleviating malaria disease severity 12:45-15:00 Lunch break Thursday, June 26, 2014 15:00-17:30 Workshop Session Workshop 1 Finding and evaluating biomarkers for infectious diseases in high throughput data Expert: F. Klawonn, Helmholtz Centre for Infection Research, Braunschweig Room: Workshop 2 KSHV (tbc) Expert: T. Schulz, Hannover Medical School Room: Workshop 3 Human microbial ecosystems Expert: T. Strowig, Helmholtz Infection Research, Braunschweig Room: Workshop 4 HCV/HBV Expert: R. Heidelberg Room: Bartenschläger, Centre for University Introduction of the career lecture: V. Wray 17:30 18:30 Career lecture: How to succeed in science without really trying? J. Yewdell, National Institute of Allergy and Infectious Diseases, Bethesda Farewell Dinner Friday, June 27, 2014 CHECK-OUT until … 07:00-09:00 Breakfast Session V: Bacteria Chair: N.N. 09:30 W. Hardt, Swiss Federal Institute of Technology, Zurich General lecture: Salmonella enterica, a common cause of diarrhea 10:00 U. Schaible, Research Center Borstel General lecture: Tuberculosis, return of a long-term notorious human companion 10:30 T. Decker, University of Vienna General lecture: Listeria and immunity 11:00 Coffee break 11:30 W. Hardt, Swiss Federal Institute of Technology, Zurich Special lecture: The importance of phenotypic diversification during Salmonella gut infection 12:00 T. Decker, University of Vienna Special lecture: Interferons and their signal transducers as mediators of innate immunity to Listeria monocytogenes 12:30 U. Schaible, Research Center Borstel Special lecture: Killing to survive: Host-pathogen interaction in tuberculosis 13:00 N.N.: Closing remarks Distribution of awards and certificates 13:15 Departure