8th Annual Convention (2003) - Natural Products Society of the
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8th Annual Convention of the Natural Products Society of the Philippines Conserving Biodiversity through Research 5-6 December 2003 8:30 am – 4:30 pm Hotel Veniz Baguio City, Philippines PLENARY LECTURES Reversing the Theme: Directing Research through Biodiversity Page ………………… 1 ………………… 9 ………………… 15 ………………… 26 ………………… 30 ………………… 33 Lourdes B. Cardenas, Dr.rer.nat Associate Professor of the Institute of Biological Sciences and Director of Natural History, University of the Philippines, Los Baños Concealed Bioactive Compound of Ginseng Kazuo Yamasaki Emeritus Professor Graduate School of Biomedical Sicences, Hiroshima University, Hiroshima 734-8551 Japan From Phytotherapy to Recombinantorial Biochemistry: Drugs of the Future Robert Verpoorte Division of Pharmacognosy, Leiden/Amsterdam, Center for Drug Research, PO box 2300RA, Leiden, The Netherlands, Email: VERPOORT@LACDR.LeidenUniv.NL ORAL PRESENTATION Antitubercular Triterpenoids from the Hexane Fraction of the Leaf Extact of Ficus nota (Blanco) Merr. Aneline P. Tolones1, Mary J. Garson2, Scott G. Franzblau3 and Alicia M. Aguinaldo4 1Graduate School & Research Center for the Natural Sciences, University of Santo Tomas, Manila and Chemistry Department, University of San Agustin, Iloilo City 2Marine Natural Products Laboratory, Department of Chemistry, School of Molecular and Microbial Sciences, University of Queensland Brisbane, Australia 3Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA 4College of Science and Research Center for the Natural Sciences, UST, Manila Isolation and Chemical Characterization and Biological Activity of Antimicrobial Compound from the Fruit Peel of Lansium domesticum Correa (Meliaceae) Eufrocinio C. Marfori1, Shin’ ichiro Kajiyama2, Ei-ichiro Fukusaki2, and Akio Kobayashi2 1University Researcher, Antional Institute of Molecular Biology and Biotechnology, University of the Philippines, Los Baños, College, Laguna 4031 Philippines 2Assistant Professor, Associate Professor and Professor, respectively, Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871 Japan Syntheses of Vancomycin Analogues with Potential Antimycobacterial Activity Titos Anacleto O. Quibuyen, Portia Mahal G. Sabido, Mary Jane L. Felipe Institute of Chemistry, University of the Philippines, Diliman, Quezon City Development of a Targeted Effecacious Immunosuppresant Bioconjugate of a Marine Metsbolic Gisela P. Concepcion1, Endoma2, Acosta3, Padlan1, ………………… 39 ………………… 45 ………………… 46 ………………… 48 ………………… 52 ………………… 55 ………………… 58 ………………… 60 Padua4, Mary Ann A. L.P. E.A. F. Marianne Cabana5, D. de Guzman1, J. Madrazo1 1Marine Science Institute, UP Diliman, Quezon City 2Institute of Chemistry and Natural Sicence Research Institute, UP Diliman, Quezon City 3Immunology, Research Institute for Tropical Medicine, Alabang, Muntinlupa 4Immunology Laboratory, NKI 5Institute of Chemistry, UP Diliman, Quezon City A Computer-Assisted 13C-NMR Spectroscopic Identification of Components of a Mixture Armando Jerome H. De Jesus, Jr. and Fabian M. Dayrit Department of Chemistry, School of Science and Engineering, Ateneo de Manila University, Katipunan Ave., Loyola Heights, Quezon City Novel Hetercyclic Metabolites from Modified Strains of Sttreptomyces rimosus Myrna A. Deseo1,Ilain S. Hunter2 and Peter G. Waterman3 1University Researcher, National Institute of Molecular Biology and Biotechnology (BIOTECH), University of the Philippines, Los Baños, College, Laguna 4031, Philippines 2Professor, Department of Pharmaceutical Sciences, University of Strathclyde, Glasglow G1 1XW, Scotland, U.K., 3Professor, Centre for Phytochemistry, Southern Cross University, Lismore, New South Wales 2480, Australia Chemical Modifications of Marine Sponge Metabolite Adociaquinone B for Improved Cytotoxicity to Human Non-Small Cell Lung Carcinoma Cell Line A540 Mary Ann A. Endoma1, Gisela P. Concepcion2 and Ma. Criser Abad3 1Institute of Chemistry, University of the Philippines, Diliman, Quezon City 2Marine Science Institute, University of the Philippines, Diliman, Quezon City 3Office of the Vice Chancellor for Research and Development, University of Philippines,Diliman, Quezon City Synthesis of Microcionamide Gisela P. Concepcion1, Mary Ann A. Endoma2, Chris M. Ireland3, Gina Mangalindan1, A.R.J. Anas1 and Jaclyn Elizabeth R. Santos4 1Marine Science Institute, U.P. Diliman, Quezon City 2Institute of Chemistry and National Science Research Institute, U.P. Diliman, Quezon City 3Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, U.S.A. 4Institute of Chemistry, U.P. Diliman, Quezon City Triterpenes in Callus Cultures of Vitex negundo L. Marissa G. Noel1 and Fabian M. Dayrit2 1 De La Salle University and 2Ateneo de Manila University Prediction of Ligand Binding Sites in Insect Proteins by Molecular Docking Simulation Edwin P. Alcantara, Leonardo S. Cadiente III, and Myrna Deseo National Institute of Molecular Biology and Biotechnology, University of the Philippines, Los Baños, College, Laguna 4031 POSTER PRESENTATION Nutraceuticals: Prevention Rather than Cure Irene M. Villaseñor Institute of Chemistry, University of the Philippines, Diliman Metarhizium anisopliae, a Fungl Source of Cytotoxic Metabolites ………………… 61 ………………… 62 Florecita S. de Guzman1,2, Chona T. dela Cruz2, Lina T. Villacarlos3 and Flerida Cariño1,2 1institute of Chemistry and 2Natural Sciences Research Institute, University of the Philippines, Diliman, Quezon City 3Department of Plant Protection Leyte State University, Visca, Baybay, Leyte Isolation of Cytotoxic Compound from a Batanes Sponge Dysidea sp. Gina C. Mangalindan1, Zenaida Bojo1, Mary Kay Harper2, Chris M. Ireland2 and Gisela P. Concepcion1 1Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines 2Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA Phenolic Compounds on Lagerstroemia speciosa (L.) Pers. (Banaba) with Antioxidant Properties 63 ………………… Teresite L. Manansalaa,b,c,Erlinda I. Espesoa,b, Satoru Itod, Masashi Hisamotoe, Nobuji Nakatanie and Kazuo Yamasakid aDepartment of Chemistry, College of Science bResearch Center for the Natural Sciences cGraduate School, University of Santo Tomas, España Street, Manila 1008 dDepartment of Pharmacognosy, Division of Medicinal Chemistry, Geaduate School of Biomedicinal Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku Hiroshima, Japan eGraduate School of Human Life Science, Osaka City University, Japan Antimicrobial Activity of Compounds Isolated from Syzygium samarengense (Blume) Merr. & L.M. Perry ………………… 64 ………………… 65 ………………… 66 ………………… 67 Evangeline C. Amor1, Irene M. Villaseñor1, M. Iqbal Choudhary2, M. Habiba2, M. Kaukab Farhana2 and M. Naseena2 1 Institute of Chemistry, University of the Philippines, Diliman, Quezon City 2HEJ Research Institute of Chemistry, University of Karachi, Pakistan Isolation and Structure Elucidation of Potential Antioxidants from Pandanus dubius Spreng. Brenda Singco1, Mariko Kitajima2, Hiromitsu Takayama2, Norio Aimi2 and Maribel Nonato3 1 Graduate School, University of Santo Tomas, España Street, Manila 1008 2Graduate School of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan 3Research Center for the Natural Sciences, Thomas Aquinas Research Complex, University of Santo Tomas, España, Manila 1008, Philippines Synthesis of Anti-Diarrheal Agents from Sapal (Drimys piperita Hook L.) Leaves Mary Ann E. Endoma1, Susan Arco1, Annie Magpusao1,2, Ma . Celeste Tria1, M. Reyes1, Irene Villaseñor1 1 Institute of Chemistry and 2 Natural Science Research Institute, University of the Philippines, Diliman, Quezon City Leaf Extracts from Cassia alata L. (Akapulko) Induce Quinone Reductase Enzymes and Compete for Estrogen Receptor Binding Indicating Cancer Chemopreventive Property Sonia D. Jacinto1, Elizabeth Olarte2, Marina Galvez-Peralta3, Irene Villaseñor2, John M. Pezzuto4 , 1 Institute of Biology, University of the Philippines, Diliman, Quezon City, Philippines, 2 Institute of Chemistry, University of the Philippines, Diliman, Quezon City, Philippines,3 Pharmacognosy Department, University of Seville, Seville, Spain, 4 Department of Medicinal Chemistry and Pharmocognosy, College of Pharmacy, University of Illinois at Chicago Hepaprotective Antioxidant Activities of Five Philippine Medicinal Plants ………………… 68 ………………… 69 ………………… 70 ………………… 71 ………………… 72 ………………… 73 ………………… 74 ………………… 75 ………………… 76 ………………… 77 Glorina C. Pocsidio, Florence S. Binua, Ramil P. Herrera, Rosalie Ivy N. Leyesa, and Ronald Eric D. Tamondong Institute of Biology, College of Science, University of the Philippines, Diliman, Quezon City, Philippines Anthelminthic Potential of the Bark and Flowers of Vernonia cinerea Against Fasciola hepatica Linn. Adult Worm Kenneth Dy1, Antonio Reyes Jr.1, Dianne Nitural1 and Gil A. Cauyan1,2 1College of Science and , University of Santo Tomas 2College of Science and Research Center for the Natural Sciences, Thomas Aquinas Research Complex, University of Santo Tomas, Manila, 1008 Fungistatic Efficacy of Selected Plant Extracts Against Fusarium moniliforme (Sheldon) Causing Corn Ear Rot Disease Ms. Miladis M. Afidchao Biologist II, Research Department, Isabela State University, Echague, Isabela Bioactivity Studies on Three Endemic Philippine Plants Amelia P. Guevarra1, and Lilibeth A. Salvador1 1Natural Products Research Laboratory, Institute of Chemistry, University of the Philippines, Diliman The Cardioactivity Potential of the Aromatic Tubers of the Purple Nutsedge, Cyperus rotundus L. Glorina C. Pocsidio1,2, Regina C. Nava1, Hiyas A. Junio2, and Thucydides L. Salunga1 1 Institute of Biology, 2Natural Sciences Research Institute, College of Science, University of the Philippines, Diliman, Quezon City, Philippines Vasorelaxant Activity of Cyperus rotundus L. in both Endothelium-Intact and Denuded Guinea Pig Thoracic Aortic Rings Pocsidio1,2, 1 Nasal1 Salunga1 Glorina C. Maaria Vctoria Rosanne L. and Thucydides L. Institute of Biology, 2Natural Sciences Research Institute, College of Science, University of the Philippines, Diliman, Quezon City, Philippines Actinomycetes as Potential Source of Bioactive Compounds Teofila O. Zulaybar1, E.C. Marfori1, M.A. Deseo1, I.A. Papa1, B.C. Mercado1, and A.K. Raymundo2 1National Institute of Molecular Biology and Biotechnology (BIOTECH), University of the Philippines, Los Baños (UPLB), College, Laguna 2Institute of Biological Sciences (IBS), College, Laguna Screening of Philippine Plants for Larvaecidal Activity on Aedes aegypti Susan D.R. Arco,Ph.D.1 and Genalyn Alice S. Ramos1 1Institute of Chemistry, College of Science, University of the Philippines, Diliman, Quezon City 1101 Extraction and Evaluation of Bioactive Components from Selected Botanicals as Biofungicides against Major Fungal Diseases of Root Crops M.K. Palomar1, E.O. Landerito2, A.P. Molato and D.S. Canayong 1Departmetn of Pest Management, Leyte State University 2Department of Pure and Applied Chemistry, LSU Insecticidal Potential of the Formulated Tobacco Seed, Nicotiana tabacum, L. Oil Shirley C. Agrupis and Arthur A. Cacacho Mariano Marcos State University College of Arts and Sciences, Batac, Ilocos Norte Fax No. 077-792-3191 Email: SCAgrupis@digitelone.com Effect of Divalent and Trivalent Ions on the Fibril Formulation of β-2Microglobulin Rex Darell B. Vergel2, Noel Quiming1, Panlilio1, ………………… 78 ………………… 79 ………………… 80 ………………… 81 ………………… 82 ………………… 83 ………………… 84 ………………… 85 ………………… 86 ………………… 87 Reyes1 Mara Teresa Maria Fritzie and James Villanueva2 1Institute of Chemistry, University of the Philippines, Diliman, Quezon City 2Natural Science Research Institute, University of the Philippines, Diliman, Quezon City Analysis of β-2-Microglobulin Using Ultracentrifugation and Raman Spectroscopy Nesha Andor1, Noel Quiming1, Mara Teresa Panlilio1, Rex Darell B. Vergel2, Maria Fritzie Reyes1 and James Villanueva2 1Institute of Chemistry, University of the Philippines, Diliman, Quezon City 2Natural Science Research Institute, University of the Philippines, Diliman, Quezon City Phylogeny of the Water Monitor Lizard or “Bayawak” (Varanus salvator) Based on Seqences of Key Conserved Mitochondrial Genes Ponce de Leon, M.I.A.Z, Hedreyda, C.T.H. Molecular Microbiology Laboratory, National Institute of Molecular Biology and Biotechnology, University of the Philippines, Diliman Phylogeny of the Visayan Warty Pig (Sus cebifrons) Based on Seqences of Key Conserved Mitochondrial Genes Ponce de Leon, M.I.A.Z, Hedreyda, C.T.H. Molecular Microbiology Laboratory, National Institute of Molecular Biology and Biotechnology, University of the Philippines, Diliman Genomic DNA Studies of Some Philippine Aromatic and Herbal Plants: Isolation Protocol Optimization, DNA Profiling and Characterization Vivian A. Panes, Merab A. Chan, Vivian S. Tolentino and Ralph Arnold S. Lasala Biology Department, School of Science and Engineering, Loyola Schoola, Ateneo de Manila University, Loyola Heights, Quezon City Investigation of the DNA of Some Philippine Aromatic and Herbal Plant: Breaking New Grounds in Philippine Medicinal Plant Research Vivian A. Panes, Merab A. Chan, Vivian S. Tolentino and Ralph Arnold S. Lasala Biology Department, School of Science and Engineering, Loyola Schoola, Ateneo de Manila University, Loyola Heights, Quezon City Implication of Hg Pollution in Biodiversity Titos Quibuyen1, Emelina Regis2, Fritzie dela Cruz2, Malona Velasco3, Danilo Lagunsad4, Gilda Romero4 1Institute of Chemistry, UP Diliman 2Department of Biology, Ateneo de Naga, Naga City 3Department of Biology, University of San Carlos, Cebu City 4Departmet of Biology, UP Diliman Comparison of a Silica Gel from Rice Hull to Chromatographic Silica Gels Leni L. Quirit and Elma Llaguno Institute of Chemistry and Natural Sciences Research Institute, UP Diliman, Quezon City Genetic Diversity in Selceted Zingiberaceae Spp. Using RAPD Markers Remedios R. Roderos1,2 and Erna L. Elias2 1Institute of Biology and 2 Natural Sciences Research Institute, UP Diliman, Quezon City Chiral Drug Separation by Reagents from Philippine Medicinal Plants Florentino C. Sumera and Marlon T. Conato Institute of Chemistry and Natural Sciences Research Institute, UP Diliman, Quezon City Diversity in Structure and Distribution of Calciium Crystals in Some Medicinal Plants ………………… 88 ………………… 89 ………………… 90 ………………… 91 ………………… 92 ………………… 93 ………………… 94 ………………… 96 Vivian S. Toletino, Ansama A. Amante P., Cabahug M, Arzaga L., Lasala R., and Panes V. Department of Biology, School of Science and Engineering, Ateneo de Manila University, Loyola Heights, Quezon City Induction of Seed Germination In Carmona retusa (Vahl) Masam. (Tsaang Gubat) Lilian B. Ungson Institute of Biology, Universitty of the Philippines, Diliman, Quezon City Removal of Heavy Metals in Waste Water using Barks of Industrial Tree Plantation Species (ITPS) Jennifer P. Tamayo1 and Maxima E. Flavier2 1Forest Products Research and Development Institute (FRDI)-DOST, College , Laguna 2Institute of Chemistry, University of the Philippines, Los Baños, College, Laguna Effect of Heavy Metals on Ipomoea aquatic Fork (Kangkong) Florenda S. Valera and Cherry R. Serrano Institute of chemistry, University of the Philippines, 1101 Diliman, Quezon City Comparative Analysis of Starches from Selected Fruit Seeds Dinah L. Espinell, Evalyn V. Mendoza, Joy-belle O. Pilapil, Kim Albert P. Perlado Cavite State University, Indang, Cavite Food Flavors as Potential Preservative Systems Delia de Castro-Ontengco1, Teresita V. Capal2, Catherine L. Melo2, and Lourdes A. Dayap2 1Biological Sciences Department, Medical Affairs Division, United Laboratories Inc., Mandaluyong City Fax No. 663-7767; email: dcontengco@unilab.com.ph 2Inustrial Technology and Development Institute, Department of Science and Technology, Bicutan, Taguig Screening for the Inhibitory Effect of the Polar and Non-Polar Extracts of Local Plants against some Pathogenic Bacteria Milona L. Santos, Paul B. Tagarro, Carolyn A. Arbotante, Kerry Jane B. Ruadil, Mary Jho-Anne T. Corpuz, Merlyn C. Cruz, Ma. Rita Y. Espino, Madonna R. De Leon, Mona Lisa B. Lacson, Crizelda D. Liwanag, Bella G. Panlilio, Bernard C. Silvala and Ruth V. Tolentino Department of Chemistry, Angeles University Foundation, Mc Arthur Hi-way, Angeles City, Philippines Enzymes: Nature’s Way of Recycling Paper Adela S. Torres1, Calvin P. Estudillo1 and Ramon A. Razal2 1Researches, Forest Products Research and Development Institute, DOST, College, Laguna 2Dean, College of Forestry and Natural Resources, UPLB, College, Laguna
