Online Biochemistry Course, Faculty of Medicine, University of Toronto, Canada Course Schedule Fall Semester 28 September 2015 to 20 Feb 2016 Week 1&2 Section / Online Quiz Biochemistry Basics and Proteins Dates (Week Start) 28 Sep 2015 Video Lecture Topics Lecturer Course Introduction to Biochemistry Dr. Reithmeier Text Chapter Clinical Insights By Dr. Murray 1 Water and pH Balance Water and pH 2 Vitamin C Deficiency Causes Scurvy Amino Acids 3 Protein 3D Structure 4 5 Quiz 1 3&4 13 Oct 2015 **QUIZ MOVED TO TUESDAY 12 Oct 2015 Enzymes Dr. Baker Hemoglobin 6-8 9 Variations in Km Can Have Physiological Consequences Sickle Cell Anemia Quiz 2 5&6 26 Oct 2015 26 Oct 2015 Carbohydrates Dr. Baker 10 Lactose Intolerance Lipids Dr. Reithmeier 11 Digitalis Membranes: Structure and Function 7&8 Quiz 3 09 Nov 2015 Metabolism 09 Nov 2015 Quiz 4 9 & 10 Dr. Baker 15, 16 Exercise Depends on Various Means of Generating ATP Glycogenolysis 24 PDC, TCA, ETC, Ox.Phos/PMF 18 – 21 Beriberi-A Disease Due to Deficiency Of Thiamine (Vitamin B-1) 27-29 Hyperglycemia Insulin 13, 27 GSDs Glycogen Synthesis 25 Diabetes 27 GNG 17 23 Nov 2015 23 Nov 2015 Quiz 5 Metabolism, Glycolysis 12, 13 Fat Catabolism, Fat Synthesis 07 Dec 2015 Page 1 of 2 Dr. Baker Week Section / Online Quiz 11 & 12 Dates (Week Start) 07 Dec 2015 Video Lecture Topics Lecturer Cholesterol Dr. Baker Text Chapter Clinical Insights By Dr. Murray 29 Tay-Sachs Disease Lipoproteins 29 Eicosanoids 28 Inherited Defects Of The Urea Cycle Cause Hyperammonemia PI Synthesis and Signalling 29, 13 AA Synthesis and Degradation Dr. Reithmeier 30, 31 Nucleic Acid Structure Dr. Kelley 33 Nucleotide Metabolism Dr. Reithmeier 32 DNA Replication Dr. Kelley 34 BREAK (19 Dec 2015 to 03 Jan 2016) 13 & 14 Quiz 6 04 Jan 2016 Nucleic Acids 04 Jan 2016 DNA Repair Quiz 7 15 & 16 17 & 18 Transcription Dr. Kelley 36 Gene Expression, Regulation 37 RNA Processing 38 Mutations that Affect pre-mRNA and Alternative Splicing Cause Disease 01 Feb 2016 01 Feb 2016 MOCK Quiz Cancers Are Caused by Defective Repair of DNA 18 Jan 2016 18 Jan 2016 Quiz 8 35 Some Genetic Diseases Are Caused by The Expansion of Repeats of Three Nucleotides Genetic Code, tRNAs and Amino Acids Translation, Translation Regulation 40 Some Antibiotics and Some Toxins Act by Inhibiting Protein Synthesis Protein Secretion 40 Gene Therapy, Transgenic Animals Recombinant Technologies 41 Available 15 Feb 2016 Final Examination 2016 Date 20 February 2016 Time 9:30 am - 12:30 pm Material Tested Final exam includes all topics covered throughout the course Page 2 of 2 Dr. Kelley 39