LIFS 3240-2015 LIFS 3240: Lecturer: Tutor Introduction to Neurobiology (Spring 14/15) Prof. Karl Tsim (Course Director) Prof. Hsiaoming B. Peng Dr. Wing Leung (lkwing@ust.hk) Rm 5456 Rm 5461 Rm 6145 10:30 – 11:50 10:30 – 11:50 X-7332 X-7321 X-7338 Time: Monday Wednesday Rm 6591 Rm 6591 Text Book: From Neuron to Brain Nicholls et al. 2001 Sinauer Foundations of Neurobiology Delcomyn 1998 Freeman Neuroscience Purves et al. 1997 Sinauer Web site at http://lmes2.ust.hk/portal# Intended Learning Outcome: 1. 2. 3. 4. 5. To gain knowledge in fundamental principles of neurobiology; To learn to appreciate and to evaluate neuroscience literature; To cultivate ability in communication and appreciation of neuroscience; To train interpersonal skills in developing collaborative projects; To incubate interests and preparation for career path. Project and Presentation: Mid-Term Exam: Final Exam: 10% 30% 60% ______________________________________________________________________ Topics Time Lecturer ______________________________________________________________________ 1. An overview Brain and behaviour 2. 4/2 9/2 TSIM TSIM 11/2 TSIM 16/2 18/2 18/2 TSIM TSIM TSIM Functional anatomy of the central nervous system Anatomical organization Regional anatomy and image of the brain Cerebrospinal fluid and blood-brain barrier 4. TSIM Cell and molecular biology of neuron Nerve cells and behaviour The cytology of neurons and glia Synthesis and trafficking of Neuronal proteins 3. 2/2 Motor system 1 LIFS 3240-2015 Muscle contraction Muscle receptors and reflexes Cerebellum Basal ganglia Occular motor system 5. 23/2 25/2 25/2 2/3 2/3 TSIM TSIM TSIM TSIM TSIM 4/3 PENG 9/3 11/3 PENG Synaptic transmission and The mechanism of transmitter release The biology of neurotransmitters 16/3 18/3 PENG PENG Mid-term exam (1 hour) 23/3 TSIM Membrane properties Ionic basis of the resting potential Ionic basis of the action potential and Neurons as conductors 6. 7. Synaptic transmission Myelination, synaptic plasticity and blood-brain barrier Synaptic plasticity PNS and CNS myelination Sleep Neurodegenerative diseases 8. 25/3 25/3 30/3 30/3 PENG PENG PENG PENG 1/4 13/4 PENG PENG Visual system Auditory and vestibular system Somatosensory system and pain Chemical senses 15/4 20/4 20/4 22/4 PENG PENG PENG PENG Presentation (Project guideline will be given soon) 27/4 29/4, 4/5 ALL STAFFS Homeostasis Autonomic nervous system Hypothalamus and limbic system 9. Sensory system Review TSIM/PENG 6/5 Final examination 2 hours 2