CV - UC San Diego Health Sciences - University of California, San

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S HYAM S.

J ANI , P H .D.

EDUCATION

AWARDS

Department of Radiation Medicine & Applied Sciences

University of California, San Diego / Moores Cancer Center

3855 Health Sciences Drive, MC0843

La Jolla, CA 92093-0843 / ssjani@ucsd.edu

University of California – San Diego

Residency in Medical Physics

University of California – Los Angeles

Ph.D. in Biomedical Physics

M.S. in Biomedical Physics

University of California – Berkeley

B.S. in Bioengineering

RESEARCH EXPERIENCE

Department of Radiation Oncology, University of California – Los Angeles

Advisor: James M. Lamb, Ph.D.

Project: Automatic detection of patient positioning and identification errors

• Results presented to the hospital Oncology Advisory Committee

Project: Marker-based localization of prostate cancer

• Abstract presented at ASTRO 2007 (poster)

Moses A. Greenfield Award (University of California – Los Angeles)

Norm Baily Award (Southern California Chapter of AAPM)

Ursula Mandel Fellowship (University of California – Los Angeles)

PROFESSIONAL ACTIVITIES

Professional memberships:

American Association of Physicists in Medicine

Editorial reviewer:

Medicine & Biological Engineering & Computing

Journal of Experimental & Theoretical Artificial Intelligence

• Manuscript published in Practical Radiation Oncology (2015)

• Three abstracts presented at AAPM 2014 (oral, poster) and AAPM 2015 (poster)

Project: Investigation of gating algorithms for lung tumor volume delineation

• Manuscript published in Int J Radiat Oncol Biol Phys (June 2013)

• Two abstracts presented at ASTRO 2011 (poster) and AAPM 2013 (oral)

Project: Utility of maximum intensity projections to identify mobile lung target volumes

• Manuscript published in Annals of Nuclear Medicine (Oct. 2014)

• Two abstracts presented at AAPM 2011 (oral) and AAPM 2012 (oral)

Mentorship: Advised 5 foreign graduate students on research topics and MATLAB implementation

Department of Bioengineering, University of California – Berkeley

Advisor: Song Li, Ph.D.

Project: Hydrogel elasticity properties for mesenchymal stem cell differentiation

• Data used in Park et al., Biomaterials (June 2011)

Department of Integrative Biology, University of California – Berkeley

Advisor: Mimi A. R. Koehl, Ph.D.

Project: Aerodynamic performance of Microraptor gui

• Work contributed to Koehl et al., Integrative and Comparative Biology (Sept. 2011)

Department of Radiation Oncology, Sharp Memorial Hospital

Advisor: Geoffrey Weinstein, M.D.

Project: Evaluation of post-treatment PSA levels for prostate cancer patients

San Diego, CA

June 2015 - Present

Los Angeles, CA

Berkeley, CA

June 2015

Sept. 2012

May 2009

Los Angeles, CA

Sept. 2010 - June 2015

Berkeley, CA

Sept. 2008 - May 2009

Berkeley, CA

Sept. 2007 - May 2008

San Diego, CA

June 2008 - Aug. 2008

June 2006 - Aug. 2006

2014

2014

2013 - 2014

2012 - Present

2014

2015

Shyam S. Jani CV Page 2

PUBLICATIONS

Peer-reviewed publications:

1.

Jani SS , Low DA, Lamb JM. Automatic detection of patient identification and positioning errors in radiotherapy treatment using 3D setup images. Accepted in Practical Radiation Oncology. DOI: http://dx.doi.org/10.1016/j.prro.2015.06.004

2.

Kishan AU, King CR, Jani SS , Kang JJ, Steinberg ML, Lamb JM. Pelvic nodal dosing with registration to the prostate: implications for high-risk prostate cancer patients receiving SBRT. Int J Radiat Oncol Biol Phys 2015; 91 (4): 832-9.

3.

Jani SS , Lamb JM, Robinson CG, Dahlbom M, White BM, Low DA. Assessing margin expansions of internal target volumes in

3D and 4D PET: a phantom study. Annals of Nuclear Medicine 2015; 29 (1): 100-109.

4.

White BM, Santhanam A, Thomas DA, Min Y, Lamb JM, Neylon J, Jani S , Gaudio S, Srinivasan S, Ennis D, Low DA. Modeling and incorporating cardiac-induced lung tissue motion in a breathing motion model. Med Phys 2014; 41 (4): 043501.

5.

Thomas D, Lamb J, White B, Jani S , Gaudio S, Lee P, Ruan D, McNitt-Gray M, Low D. A novel fast helical 4D-CT acquisition technique to generate low-noise sorting artifact-free images at user-selected breathing phases. Int J Radiat Oncol Biol Phys

2014; 89 (3): 191-8.

6.

Jani SS , Robinson CG, Dahlbom M, White BM, Thomas DH, Gaudio S, Low DA, Lamb JM. A comparison of amplitude-based and phase-based positron emission tomography gating algorithms for segmentation of internal target volumes of tumors subject to respiratory motion. Int J Radiat Oncol Biol Phys 2013; 87 (3): 562-9.

7.

Low DA, White BM, Lee PP, Thomas DH, Gaudio S, Jani SS , Wu X, Lamb JM. “A novel CT acquisition and analysis technique for breathing motion modeling.” Phys Med Biol 2013; 58 (11): L31-6.

Abstracts and presentations:

1.

Jani S , O’Connell D, Chow P, Agazaryan N, Low D, Lamb J. Automatic detection of patient identification and patient positioning errors using 3D setup images. Med Phys 2014; 41 (6): 96.

2.

Jani S , Kishan A, O’Connell D, King C, Steinberg M, Low D, Lamb J. Prediction of pelvic nodal coverage using mutual information between cone-beam and planning CTs. Med Phys 2014; 41 (6): 198.

3.

O’Connell D, Chow P, Agazaryan N, Jani S , Low D, Lamb J. Prediction of dosimetric endpoints from patient geometry using neural nets. Med Phys 2014; 41 (6): 397.

4.

Thomas D, Tan J, Neylon J, Dou T, Jani S , Lamb J, Low D. Investigating the minimum scan parameters required to generate free-breathing fast-helical CT scans without motion-artifacts. Med Phys 2014; 41 (6): 559.

5.

Kishan AU, King CR, Jani S , Steinberg ML, Lamb J. Pelvic nodal dosing with registration to the prostate: implications for high-risk prostate cancer patients receiving SBRT. Int J Radiat Oncolo Biol Phys 2014; 91 (1): S410.

6.

Low DA, Thomas DH, Lamb JM, Lee PP, Gaudio S, Jani S , Dou T, White B, Wu X. Comparison between existing and proposed

4DCT protocols. Radiother Oncol 2014; 111 : S196-S197.

7.

Thomas D, White B, Gaudio S, Jani S , Lee P, Lamb J, Low D. A novel 4D CT acquisition and analysis technique to account for the effect of cardiac induced lung tissue motion during free breathing. Med Phys 2013; 40 (6): 411.

8.

Thomas D, White B, Gaudio S, Jani S , Lee P, Lamb J, Low D. A novel 4D CT acquisition and analysis technique to generate low noise artifact-free images at user selected breathing phases. Awarded Best in Physics (Joint Imaging-Therapy) .

Med Phys 2013; 40 (6): 456.

9.

Gaudio S, Thomas D, White B, Jani S , Lee P, Lamb J, Low D. Breathing motion comparison inside and outside the lung. Med

Phys 2013; 40 (6): 182.

10.

Wu X, Jani S , Dahlbom M, Low D, Lamb J. Comparing the accuracy of the bilateral filter and Gaussian filter for PET image post-processing through a phantom study. Med Phys 2013; 40 (6): 144.

11.

Jani S , Dahlbom M, White B, Thomas D, Gaudio S, Low D, Lamb J. Comparison of gating algorithms in 4D-PET for mobile tumor segmentation. Med Phys 2013; 40 (6): 106.

12.

Low D, Thomas D, White B, Gaudio S, Jani S , Lee P, Lamb J. Development of a prospective gating algorithm for a novel

4DCT technique: retrospective data analysis. Med Phys 2013; 40 (6): 179.

13.

Lamb J, Jani S , White B, Thomas D, Gaudio S, Robinson C, Low D. Ground-truth tests of deformable image registration using matched PET-CT image pairs. Med Phys 2013; 40 (6): 169.

14.

Aliotta E, Thomas D, Gaudio S, White B, Jani S , Lee P, Lamb J, Low D. Improving image quality in 4D-CT scans using deformable registration and selective averaging. Med Phys 2013; 40 (6): 434.

Shyam S. Jani CV Page 3

15.

White B, Thomas D, Lamb J, Jani S , Gaudio S, Min Y, Srinivasan S, Ennis D, Santhanam A, Low D. Modeling cardiac induced lung tissue motion for a quantitative breathing motion model. Med Phys 2013; 40 (6): 470.

16.

White B, Santhanam A, Wang Z, Jani S , Lamb JM, Ennis D, Ruan D, Low D. Addition of cardiac motion in a breathing motion model. Int J Radiat Oncolo Biol Phys 2012; 84 (3): S746.

17.

Jani S , Lamb JM, Dahlbom M, Robinson C, White B, Low D. 4D-PET maximum intensity projections improve accuracy of mobile tumor volume delineation. Med Phys 2012; 39 (6): 3970.

18.

Lamb JM, Lee P, Jani S , Dahlbom M, White B, Low D. 4D-PET for abdominal tumor target volume generation. Med Phys

2012; 39 (6): 3691.

19.

Jani S , Lamb JM, Dahlbom M, Robinson C, White B, Low D. 4D-PET maximum intensity projections improve accuracy of mobile tumor volume delineation. Poster presentation at the 13 th Annual Biomedical Physics Research Colloquium; May

18, 2012; Los Angeles, CA.

20.

Lamb JM, Robinson CG, Jani S , Laforest R, Bradley JD, Dehdashti F, White BM, Dahlbom M, Lee P, Low DA. Comparison of

4D-PET gating methods with regards to determining internal target volumes of mobile lung tumors. Int J Radiat Oncolo

Biol Phys 2011; 81 (2): S816.

21.

White B, Lamb JM. Zhao T, Jani S , Low D. Distribution of tissue divergence in the apex of the lung. Int J Radiat Oncolo Biol

Phys 2011; 81 (2): S776-7.

22.

White B, Zhao T, Jani S , Lamb J, Bradley J, Low D. Distribution of hysteresis magnitude during free breathing. Med Phys

2011; 38 (6): 3606.

23.

Jani S , Lamb JM, Robinson C, et al. Utility of maximum intensity projections of gated PET images in determining internal target volumes of moving lung tumors: a phantom study. Med Phys 2011; 38 (6): 3374.

24.

Weinstein G, Jani SK, Li K, Jani S , Pothilat J, Lee S, Glazebrook S. “In-vivo comparison of marker-based localization of prostate with conventional anatomical match using stereoscopic kVp x-rays during external beam radiotherapy.” Int J

Radiat Oncolo Biol Phys 2007; 69 (3): S358.

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