Cell Physiology 2010 PBSB Program. 15 weeks X 3 hours per week Location: Tuesdays & Thursdays: 4:15 pm – 5:30 pm 1300 York Avenue, LC 5th Floor Conference Room, LC-504 Fridays: 1:30 pm – 2:30 pm 1305 York Avenue, ICB 13th Floor Conference Room, Y.13.01 Course Director: Crina Nimigean – (212) 746-5947, crn2002@med.cornell.edu Course TA: Romulo Hurtado (Junior), roh2002@med.cornell.edu Course Objectives: To familiarize first and second year students with common topics in cell physiology and to provide exposure to research areas relevant to PBSB faculty. The Friday sessions consist of presentation of a journal article selected by the faculty giving the lectures that week. The presentations are given by students and moderated by the faculty/TA. Course Textbooks: Cellular Physiology by Mordecai P. Blaustein, Mordecai P. Blaustein, Donald R. Matteson, Joseph P. Y. Kao Recommended: Ion Channels of Excitable Membranes by Bertil Hille Molecular Biology of the Cell by Bruce Alberts, Julian Lewis, Alexander Johnson General area Cell membranes and biophysics of the cell Genes, proteins Lecture topic Lecturer Date Course introduction Crina Nimigean 9/2 Cell membranes and phospholipids Compartments, electrolytes, osmosis Journal article presentation Membrane potential and action potentials Olaf Andersen Olaf Andersen Student David Christini 9/7 9/9 9/10 9/14 (Attend Tri-Institutional Responsible Conduct of Research course ) NO CLASS 9/16 Lucy Skrabanek Scott Blanchard 9/17 9/21 Transcription Translation Quiz 1 Proteins in the cell 9/23 Journal article presentation Protein structure/function and modification Enzyme kinetics and energetics Journal article presentation Ion channels and transporters Trimeric G-proteins and GPCRs Journal article presentation Kinases, phosphatases and other effectors 9/24 9/28 9/30 10/1 10/5 10/7 10/8 10/12 Student Olga Boudker Crina Nimigean Student Larry Palmer Harel Weinstein Student Xin-Yun Huang Quiz 2 Signaling in the cell 10/14 Journal article presentation Transcription factors Renin-Angiotensin signaling Journal article presentation Adrenergic signaling, PKA, PKC, cAMP MAP kinase pathways Journal article presentation Student Yutaka Nibu Jacqueline Brazin Student Mark Rosenblatt Gregoire Altan-Bonnet Student 10/15 10/19 10/21 10/22 10/26 10/28 10/29 1 AJR – Revised 09/14/2010 Cell Physiology 2010 Ca2+ - a ubiquitous signaling molecule Geoff Abbott 11/4 Quiz 3 Cells as complex systems 11/2 Journal article presentation The neuron as a cell system Neuronal communication Journal article presentation Student Emre Aksay Emre Aksay Student 11/5 11/9 11/11 11/12 Neuroscience Meeting NO CLASS 11/16 Neuronal plasticity Jeremy Dittman 11/18 Quiz 4 (NOTE: In ICB 13th Floor Conference Room) 11/19 Thanksgiving Break NO CLASSES 11/22-26 Retinal phototransduction and neural circuitry Apoptosis and cell death Journal article presentation The cancer cell as a complex system The cardiac myocyte as a complex system Journal article presentation Sheila Nirenberg Hao Wu Student Zeynep Gumus Cathy Hatcher Student 11/30 12/2 12/3 12/7 12/9 12/10 12/14 Quiz 5 2 AJR – Revised 09/14/2010