Cell Physiology 2011
PBSB Program. 15 weeks X 4 hours per week
Location: Conference room, Physiology 5th floor, LC 504, 4:00 – 5:15 p.m.
(N.B.!! exception: Dr. Andersen’s 9/8 lecture will be at 9:00 a.m. instead of 4:00 p.m.)
Course director: Crina Nimigean – 212-746-5947, crn2002@med.cornell.edu
Course TA: Ping Mu, pim2002@med.cornell.edu
Course objectives:
- To familiarize first and second year students with common topics in cell physiology and to
provide exposure to research areas relevant to PBSB faculty.
- The Friday sessions consist of presentation of a journal article selected by the faculty giving the
lectures that week. The presentations are given by students and moderated by the faculty/TA.
General area
Lecture topic
Course introduction
Lecturer
Crina Nimigean
Date
9/6
Cell membranes and biophysics
of the cell
Cell membranes and phospholipids
Compartments, electrolytes, osmosis
Journal article presentation
Membrane potentials and HH
Ion channels role in AP and RP
Journal article presentation
Synaptic transmission/NMJ
Olaf Andersen
Olaf Andersen
Student
Dan Gardner
David Christini
Student
Jeremy Dittman
9/6
9/8
9/9
9/13
9/15
9/16
9/20
Quiz 1
Genes, proteins
Transcription
Translation
Journal article presentation
Protein structure/function and modification
Enzyme kinetics and energetics
Journal article presentation
9/22
Lucy Skrabanek
Scott Blanchard
Student
Olga Boudker
Crina Nimigean
Student
10/11
Quiz 2
Proteins
Ion channels and transporters
Journal article presentation
Trimeric G-proteins and GPCRs
Kinases, phosphatases and other effectors
Journal article presentation
Transcription factors
Larry Palmer
Student
Harel Weinstein
Xin-Yun Huang
Student
Yutaka Nibu
Signaling in the cell
Jacqueline Brazin
Mark Rosenblatt
Student
Gregoire Altan-Bonnet
Alessio Accardi
Student
11/01
11/03
11/04
11/08
11/10
11/11
Quiz 4
11/15
Neuroscience meeting break
11/17
The neuron as a cell system
Cells as complex systems
10/13
10/14
10/18
10/20
10/21
10/25
10/27
Quiz 3
Renin-Angiotensin signaling
Adrenergic signaling, PKA, PKC, cAMP
Journal article presentation
MAP kinase pathways
Ca2+ - a ubiquitous signaling molecule
Journal article presentation
9/27
9/29
9/30
10/4
10/6
10/7
Thanksgiving Break
Emre Aksay
11/22
11/24
Neuronal communication
Journal article presentation
Retinal phototransduction and neural circuitry
Apoptosis and cell death
The cancer cell as a complex system
Journal article presentation
The cardiac myocyte as a complex system
Emre Aksay
Student
Sheila Nirenberg
Jason McCoy
Zeynep Gumus
Student
Cathy Hatcher
Quiz 5
Course textbooks:
Cellular Physiology by Mordecai P. Blaustein, Mordecai P. Blaustein, Donald R. Matteson, Joseph P. Y. Kao
Recommended:
1. Ion Channels of Excitable Membranes by Bertil Hille
2. Molecular Biology of the Cell by Bruce Alberts, Julian Lewis, Alexander Johnson
11/29
12/01
12/02
12/06
12/08
12/09
12/13
12/15