Program Schedule
Tuesday, June 19, 2007
5:30 p.m. - 7:00 p.m.
Registration (Heritage Hall, HUB-Robeson Center)
7:00 p.m. – 7:15 p.m.
Opening Remarks
(Auditorium, HUB-Robeson Center)
Joseph Reese, Ph.D. (Penn State)
Song Tan, Ph.D. (Penn State)
7:15 p.m. – 8:15 p.m.
Keynote Address (Auditorium, HUB-Robeson Center)
Robert Roeder, Ph.D. (Rockefeller University)
"Integrated functions of diverse transcriptional coactivators in
biochemically-defined systems"
8:15 p.m. – 9:15 p.m.
Reception (Heritage Hall, HUB-Robeson Center)
Wednesday, June 20, 2007
8:00 a.m. – 9:30 a.m.
Registration (for those not yet registered)
(Auditorium Lounge, HUB-Robeson Center)
Session I Dynamics/Remodeling 8:30 a.m. Noon (Auditorium, HUB-Robeson Center)
Chair: David Gilmour, Ph.D. (Penn State)
8:30 a.m. – 9:05 a.m.
Brad Cairns, Ph.D. (Huntsman Institute-HHMI)
“Mechanisms of nucleosome remodeling
by the chromatin remodeling complex RSC”
9:05 a.m. - 9:40 a.m.
Craig Peterson, Ph.D.
(University of. Massachusetts Medical Center)
“Chromatin remodeling machines”
9:40 a.m. - 10:15 a.m.
Blaine Bartholomew, Ph.D.
(Southern Illinois University School of Medicine
"Architectures of the SWI/SNF-Nucleosome Complex"
10:15 a.m. – 10:45 a.m.
Morning Break
10:45 a.m. – 11:20 a.m.
Frank Pugh, Ph.D. (Penn State)
"Genomic organization of chromatin and the transcription
machinery in Saccharomyces cerevisiae"
11:20 a.m. – 11:40 a.m.
Vasily M. Studitsky, Ph.D. (Penn State)
"The nature of the polar nucleosomal barrier
to transcription by RNA polymerase II"
11:40 a.m. - 12:00 p.m.
Yanming Wang, Ph.D. (Penn State)
"Histone citrullination by peptidylarginine deiminase
4 represses p53-target gene expression"
12:00 noon – 1:30 p.m.
Lunch Break
Session II
Epigenetics and Histone Modification
1:30 p.m. - 5:00 p.m.
(Auditorium, HUB-Robeson Center)
Chair: Frank Pugh, Ph.D. (Penn State)
1:30 p.m. – 2:05 p.m.
Yang Shi, Ph.D. (Harvard)
"Dynamic regulation of histone methylation by demethylases"
2:05 p.m. – 2:40 p.m.
Jerry Workman, Ph.D. (Stowers Inst)
"Protein complexes that modify chromatin for transcripition"
2:40 p.m. - 3:15 p.m.
Shelley Berger, Ph.D.
(University of Pennsylvania-Wistar Institute)
"Histone and factor post-translational
modifications in transcriptional regulation"
3:15 p.m. – 3:45 p.m.
Afternoon Break
3:45 p.m. – 4:20 p.m.
Kevin Struhl, Ph.D. (Harvard Medical School)
"Yeast transcriptional regulatory mechanisms"
4:20 p.m. – 5:00 p.m.
Ali Shilatifard, Ph.D. (Stowers Inst)
"The role of MLL and ELL in histone methylation
and pathogenesis of leukemia"
5:00 p.m. – 7:30 p.m.
Program Break
7:30 p.m. – 8:30 p.m.
Plenary Address
(Auditorium, HUB-Robeson Center)
Susan Gasser, Ph.D. (FMI-Basel, Switzerland)
"Subnuclear position and its effects on gene expression:
Examples from yeast and worms"
Thursday, June 21, 2007
Industrial Exhibits
VWR Scientific
10:00 a.m. - 3:00 p.m.
(Alumni Hall, HUB-Robeson Center)
Session III
RNA and Chromatin Structure
8:30 a.m. – Noon
(Auditorium, HUB-Robeson Center)
Chair: Laura Carrel, Ph.D. (Hershey Medical Center, Penn State)
8:30 a.m. – 9:05 a.m.
Sarah Elgin, Ph.D. (Washington University)
"Targeting heterochromatin formation and
gene silencing in Drosophila"
9:05 a.m. – 9:40 a.m.
Robert Kingston, Ph.D. (Massachusetts General Hospital)
"Possible roles in silencing for piRNAs"
9:40 a.m. – 10:15 a.m.
Shiv Grewal, Ph.D.
(NIH) "Heterochromatin: a versatile platform of the genome"
10:15 a.m. – 10:45 a.m.
Morning Break
10:45 a.m. – 11:20 a.m.
Barbara Meyer, Ph.D. (Berkeley)
"Targeting a repression complex to X chromosomes"
11:20 a.m. – 11:55 a.m.
Asifa Akhtar, Ph.D. (EMBL Heidelberg)
"Chromatin regulation by MSL proteins"
12:00 noon – 1:30 p.m.
Lunch Break
Oral Presentations Concurrent Platform
Sessions I and II
1:30 p.m. - 5:00 p.m.
Session I - Heritage Hall, HUB-Robeson Center
Session II - Auditorium, HUB-Robeson Center
5:00 p.m. – 7:30 p.m.
Program Break
Poster Presentations and Concurrent Reception
7:30 p.m. - 10:00 p.m.
(Alumni Hall, HUB-Robeson Center)
Friday, June 22, 2007
Session IV
Chromatin and Nuclear Landscapes
8:30 a.m. - Noon (Auditorium, HUB-Robeson Center)
Chair: Yanming Wang, Ph.D. (Penn State)
8:30 a.m. – 9:05 a.m.
Oliver Rando, Ph.D. (Harvard)
"Static and dynamic genome-wide views of the
primary structure of yeast chromatin"
9:05 a.m. – 9:40 a.m.
Karolin Luger, Ph.D. (Colorado State University-HHMI)
"Nucleosomes and their chaperones"
9:40 a.m. – 10:15 a.m.
Tom Mistelli, Ph.D.
(NIH) "Chromatin dynamics during differentiation"
10:15 a.m. – 10:45 a.m.
Morning Break
10:45 a.m. – 11:20 a.m.
Steve Henikoff, Ph.D. (Fred Hutchinson CRC)
"Epigenetic patterns generated by histone replacement"
11:20 a.m. – 11:40 a.m.
Laura Carrel, Ph.D. (Hershey Medical Center, Penn State)
"Testing genomic influences on inactive
X chromosome expression"
11:40 a.m. - 12:00 noon
Rolf Sternglanz, Ph.D. (Stony Brook University)
"Yeast Sir3 N-terminus interacts with the nucleosome core"
12:00 noon – 1:30 p.m.
Lunch Break
Oral Presentations Concurrent
Platform Sessions III and IV
1:30 p.m. - 5:00 p.m.
Session III - Heritage Hall, HUB-Robeson Center
Session IV - Auditorium, HUB-Robeson Center
Symposium Closing Remarks
(Auditorium, HUB-Robeson Center)
5:00 pm