EMBO
Workshop
The programme for this event
was reviewed and approved by the
EMBO Course Committee.
Mechanisms
of neuronal remodelling
22–26 March 2014 | Kibbutz Ein-Gedi | Israel
Program Book
A Member of the Roche Group
http://events.embo.org/14-neuronal-remodelling
This EMBO Workshop is cofunded by the Israeli Science Foundation,
the Mizarchi Foundation and is also the 43rd Katzir centre supported conference
PROGRAM
Saturday, 22 March, 2014
16:00-20:00
Arrival & Registration
18:00
Dinner
20:00-20:15
Opening Remarks
20:15-21:15
Liqun Luo, Stanford University / HHMI
Wiring specificity in the fly olfactory circuit
21:30-23:00
Welcome Cocktail
Sunday 23 March, 2014
8:00-9:00
Breakfast
Chair: Graeme Davis
9:00-9:30
Yuh-Nung Jan, UCSF / HHMI
Molecular mechanisms of axon and dendrite remodeling
9:30-10:00
Catherine Collins, University of Michigan
Studies of Wallerian degeneration in vivo: roles for membrane potential and the synapse
10:00-10:30
Alvaro Sagasti, UCLA
Skin cells regulate the morphogenesis and maintenance of sensory axon endings
10:30-10:45
Maya Shelly, Stony Brook University
Molecular mechanisms of dendrite formation during embryonic neuronal development
10:45-15:00
Float on the Dead Sea & light lunch
Chair: Dietmar Schmucker
15:00-15:30
Thomas Misgeld, Technical University Munich
Structural and functional axon dynamics after spinal cord contusion
15:30-16:00
Florence Bareyre, Ludwig-Maximilians University of Munich
Molecular regulation of axonal remodeling following spinal cord injury
16:00-16:30
Graeme Davis, UCSF
The stable brain: homeostatic control of synaptic transmission and ion channel abundance
16:30-16:45
Elva Diaz, UC Davis
SynDIG1 promotes synapse remodeling but limits plasticity during development in vivo
16:45-17:30
Coffee break
Chair: Catherine Collins
17:30-18:00
Jean-Maurice Dura, CNRS, Montpellier
The nuclear receptor regulatory module is required for Drosophila axon pruning and memory
2
18:00-18:30
Melissa Rolls, Penn State University
Dendrites degenerate and regenerate using different machinery than axons
18:30-18:45
Nicolas Loncle, King’s College
Branch severing during pruning is controlled by the ESCRT III scission machinery
18:45-20:00
Dinner
20:00-21:00
Eric Courchesne, UCSD
Autism is prenatal: new genetic and neural evidence points to prenatal beginnings and
implications for early detection
21:00-23:00
Posters and drinks
Monday 24 March, 2014
5:00-5:30
Early coffee
5:30-9:00
Visit of Masada
9.00-10:00
Breakfast
Chair: Yuh-Nung Jan
10:00-10:30
Marc Freeman, University of Massachusetts / HHMI
Cellular and molecular mechanisms of axon degeneration
10:30-11:00
Benjamin Podbilewicz, Technion, Haifa
How cell-cell fusion proteins sculpt and regenerate dendritic trees in C. elegans
11:00-11:15
Jean Livet, Institut de la Vision, Paris
Comprehensive analysis of connectivity in a central nucleus
11:15-11:45
Coffee break
Chair: Rosalind Segal
11:45-12:15
Mike Fainzilber, Weizmann Institute of Science
RNA localization for neuronal growth regulation
12:15-12:45
Christine Holt, Cambridge University
Local translation shapes axon terminals
12:45-13:00
Florence Besse, CNRS, Nice
Imp promotes axonal remodeling by regulating profilin mRNA during brain development
13:00-15:15
Lunch & Break
Chair: Marc Freeman
15:15-15:45
Beth Stevens, Harvard
Pruning CNS synapses: an active role for glia and the complement cascade
15:45-16:15
Michal Schwarz, Weizmann Institute of Science
The dialogue between the brain and the circulation at the choroid plexus plays a key role in
brain physiology, ageing and pathology
3
16:15-16:30
Anna Gorelik, Weizmann Institute of Science
Unorthodox activities of components of the complement pathway in regulation of radial
neuronal migration
16:30-16:45
Kazuo Emoto, University of Tokyo
Compartmentalized calcium transients in spatio-temporal regulation of dendrite remodeling
16:45-17:30
Coffee break
Chair: Michal Schwarz
17:30-18:00
Oren Schuldiner, Weizmann Institute of Science
A molecular switch in the transition between axon pruning and regrowth
18:00-18:30
Freda Miller, University of Toronto
Mechanisms of translational repression in the embryonic cortex
18:30-18:45
Tal Burstyn-Cohen, Hebrew University
Photoreceptor remodeling is mediated by TAM receptor signaling and is required for retinal
homeostasis
18:45-20:00
Dinner
20:00-21:00
Rachel Wong, University of Washington
Assembly, disassembly and reassembly of retinal circuits
21:00-23:00
Posters and drinks
Tuesday 25 March, 2014
8:00-9:00
Breakfast
Chair: Freda Miller
9:00-9:30
Dietmar Schmucker, VIB Vesalius Research Center
Genetic analysis of growth cone sprouting and axon branching
9:30-10:00
Beatriz Rico, Institute for Neuroscience, Alicante
FAK in neuronal cortical wiring and function
10:00-10:30
Rosalind Segal, Harvard
There and back again: Target derived neurotrophins coordinate transcription and translation
to prevent axonal degeneration
10:30-10:45
Tran Tracy, Rutgers University
Plexin-A4 controls diverse cellular responses in developing mammalian neurons through
distinct signaling domains
10:45-11:30
Coffee break
Chair: Christine Holt
11:30-12:00
Leanne Godinho, Technical University Munich
Local generation of interneurons in the zebrafish retina
4
12:00-12:30
Alex Kolodkin, John Hopkins / HHMI
Molecular mechanisms underlying visual system neural connectivity
12:30-13:00
Hwai-Jong Cheng, UC Davis
Axonal refinement in the visual system
13:00-13:15
Martin Munz, McGill University
Patterned visual stimulation drives rapid structural and functional plasticity in the retinotectal
projection
13:15-14:30
Lunch
Chair: Alvaro Sagasti
14:30-15:00
Avraham Yaron, Weizmann Institute of Science
Switching response: temporal regulation of axon guidance
15:00-15:30
Adi Mizrahi, Hebrew University
Physiological maturation of adult born neurons in the mouse olfactory bulb
15:30-15:45
Simon Hippenmeyer, IST Vienna
Unitary production and organization of excitatory neurons in the neocortex
15:45-16:00
David Miller, Vanderbilt University
The degenerin family ion channel, UNC-8, promotes activity-dependent remodeling of
GABAergic synapses in C. elegans
16:00-16:45
Coffee break
16:45-17:45
Marc Tessier-Lavigne, Rockefeller University
Molecular mechanisms of axonal dismantling
17:45-18:00
Concluding remarks
18:00
Depart to desert Gala
Wednesday 26 March, 2014
7:00-9:00
Breakfast
8:00
Depart for Jerusalem tour
9:00
Busses depart to Ben-Gurion Airport, Weizmann Institute of Science and Tel-Aviv
5
PARTICIPANT LIST
Name
Institute / Organisation / Company
E-mail
Stefanie Alber
Weizmann Institute of Science
stefanie.alber@weizmann.ac.il
Christin Albus
Weizmann Institute of Science
christin.albus@weizmann.ac.il
Ida Alyagor
Weizmann Institute of Science
idana@weizmann.ac.il
Oshri Avraham
Hebrew University Jerusalem
oshri.avraham@mail.huji.ac.il
Florence Bareyre
Ludwig Maximilians University
florence.bareyre@med.uni-muenchen.de
Anthony Barnes
Oregon Health and Sci Univ
barnesan@ohsu.edu
Oded Behar
The Institute for Medical Research, The Hebrew
University
odedb@ekmd.huji.ac.il
Florence Besse
CNRS, Nice
besse@unice.fr
Bavat Bornstein
Weizmann Institute of Science
Bavat.Bornstein@weizmann.ac.il
Kasia Bozek
CAS-MPG Partner Institute for Computational
Biology, Shanghai, China
bozek@mpi-inf.mpg.de
Peter Bradley
Ludwig Maximilian University of Munich
peter.bradley@med.uni-muenchen.de
Michael Breckwoldt
Institute of Neuroscience, Technical University
Munich
mbreckwoldt@web.de
Monika Brill
Institute of Neuronal Cell Biology, Technical
University Munich
monika.brill@lrz.tum.de
Tal Burstyn-Cohen
Hebrew University of Jerusalem
talbu@ekmd.huji.ac.il
Li Chen
Penn State University
luc156@psu.edu
Hwai-Jong Cheng
Center for Neuroscience, UC Davis
hjcheng@ucdavis.edu
Catherine Collins
University of Michigan
collinca@umich.edu
Eric Courchesne
UC San Diego
ecourchesne1949@gmail.com
Maayan Daniel
Ben-Gurion University of the Negev
maayandani@gmail.com
Graeme Davis
UCSF
graeme.davis@ucsf.edu
6
Ivan de Curtis
San Raffaele Scientific Institute and
San Raffaele University, Italy
decurtis.ivan@hsr.it
Janusz Debski
Institute of Biochemistry and Biophysics, Poland
jasio.ibb@gmail.com
Mieke Degreef
VIB - Vesalius research center, Belgium
mieke.degreef@vib-kuleuven.be
Elva Diaz
UC Davis School of Medicine
ediaz@ucdavis.edu
Ella Doron
Weizmann Institute of Science
ella.doron@weizmann.ac.il
Karin Dumstrei
The EMBO Journal
karin.dumstrei@embo.org
Jean-Maurice Dura
Institute of Human Genetics, CNRS, Montpellier
jmdura@igh.cnrs.fr
Britta Eggert
Zentrum für Molekulare Neurobiologie Hamburg
britta.eggert@zmnh.uni-hamburg.de
Anna Emde
Weizmann Institute of Science
anna.emde@weizmann.ac.il
Kazuo Emoto
University of Tokyo
emoto@biol.s.u-tokyo.ac.jp
Peter Engerer
Technical University Munich
peter.engerer@lrz.tum.de
Mike Fainzilber
Weizmann Institute of Science
mike.fainzilber@weizmann.ac.il
Haya Falk
The Hebrew University- Hadassah Medical School
falkh@mail.huji.ac.il
Konstantin Feinberg
The Hospital for Sick Children, University of
Toronto
feinberg.k@gmail.com
Marc Freeman
UMass Med School
Marc.Freeman@umassmed.edu
Roland Friedel
Icahn School of Medicine at Mount Sinai
roland.friedel@mssm.edu
Alessandro Furlan
Karolinska Institute
alessandro.furlan@ki.se
Noga Gershoni-Emek
Tel Aviv University
noga.gershoni@gmail.com
Mitrajit Ghosh
Institute for Stroke and Dementia Research,
Munich
ghosh.mitrajit@gmail.com
Shani Gluska
Tel Aviv University
sgluska@gmail.com
Delphine Gobert
Montreal Neurological Institute, McGill University
delphine.gobert@mail.mcgill.ca
Leanne Godinho
Technical University Munich
leanne.godinho@lrz.tum.de
Irena Gokhman
Weizmann Institute of Science
i.gokhman@weizmann.ac.il
Ann Goldstein
Cell Press/Neuron
agoldstein@cell.com
7
Anna Gorelik
Weizmann Institute of Science
anna.gorelik@weizmann.ac.il
Deisy Mariela Guiretti
Instituto de Neurociencias de Alicante
dguiretti@umh.es
Itai Gutman
Weizmann Institute of Science
itai.gutman@weizmann.ac.il
Yoav Hadas
Hebrew University
yoavhadas@hotmail.com
Baruch Haimson
Hebrew University
baruch.haimson@mail.huji.ac.il
Simon Hippenmeyer
Institute of Science and Technology Austria
simon.hippenmeyer@ist.ac.at
Christine Holt
University of Cambridge
ceh33@cam.ac.uk
Mrinalini Hoon
University of Washington
mhoon@uw.edu
Ausgustine Ibegbu
Ahmadu Bello University, Zaria, Nigeria
AOIBEGBU@YAHOO.COM
Anne Jacobi
Institute for Clinical Neuroimmunology, Munich
Anne.Jacobi@med.uni-muenchen.de
Yuh-Nung Jan
HHMI/UCSF
yuhnung.jan@ucsf.edu
Suhela Kapoor
National Brain Research Center, India
suhela.kapoor@gmail.com
Rashmit Kaur
Department for Neurobiology,
Vienna University, Vienna
rashmitkaur2@gmail.com
Avihu Klar
Hebrew University
avihu@cc.huji.ac.il
Tatjana Kleele
Technical University Munich
Tatjana.Kleele@lrz.tum.de
Neta Kollet
Weizmann Institute of Science
Neta.kollet@weizmann.ac.il
Alex Kolodkin
The Johns Hopkins University School of Medicine,
HHMI
kolodkin@jhmi.edu
Katarzyna Lepeta
Nencki Institute of Experimental Biology Polish
Academy of Sciences
klepeta@nencki.gov.pl
Jean Livet
Institut de la Vision, Paris
jean.livet@inserm.fr
Nicolas Loncle
MRC Centre for Developmental Neurobiology,
King's College London
nicolas.loncle@kcl.ac.uk
Liqun Luo
HHMI, Stanford University
lluo2@stanford.edu
Maria Magiera
Institut Curie
maria.magiera@curie.fr
Maya Maor
Weizmann Institute of Science
maormaya@gmail.com
Katie Matho
Institut de la Vision, Paris
katiematho@gmail.com
8
David Miller
Vanderbilt University
david.miller@vanderbilt.edu
Freda Miller
Hospital for Sick Children, University of Toronto
fredam@sickkids.ca
Adi Minis
Weizmann Institute of Science
adi.minis@weizmann.ac.il
Thomas Misgeld
Technical University Munich
thomas.misgeld@lrz.tum.de
Adi Mizrahi
Hebrew University
mizrahi.adi@mail.huji.ac.il
Martin Munz
Montreal Neurological Institute/McGill University
martin.munz@mail.mcgill.ca
Lukas Neukomm
Neurobiology Department, UMass Medical School
lukas.neukomm@umassmed.edu
Eran Perlson
Tel Aviv University
eranpe@post.tau.ac.il
Benjamin Podbilewicz
Technion- Israel Institute of Technology
podbilew@technion.ac.il
Beatriz Rico
Instituto de Neurociencias de Alicante, CSIC-UMH
brico@umh.es
Melissa Rolls
The Pennsylvania State University
mur22@psu.edu
Nimrod Rotem
Tel-Aviv University
rotemni@gmail.com
Sebastian Rumpf
Institute of Neurobiology, University of Muenster
sebastian.rumpf@uni-muenster.de
Edward Ruthazer
Montreal Neurological Institute/McGill University
edward.ruthazer@mcgill.ca
Yaara Saad
Tel Aviv University
yaarasaad@gmail.com
Alvaro Sagasti
UCLA
sagasti@mcdb.ucla.edu
Olga Sakharchuk
Nencki institute of experimental biology PAN
osakharc@nencki.gov.pl
Hadas Sar Shalom
Weizmann Istitute of Science
hadas.j@gmail.com
Benjamin Schattling
ZMNH, Hamburg
benjamin.schattling@zmnh.uni-hamburg.de
Susanne Schmidt
CRBM CNRS, Montpellier
susanne.schmidt@crbm.cnrs.fr
Dietmar Schmucker
Vesalius Research Center, VIB Leuven, Belgium
dietmar.schmucker@vib-kuleuven.be
Oren Schuldiner
Weizmann Institute of Science
oren.schuldiner@weizmann.ac.il
Michal Schwartz
Weizmann Institute of Science
Michal.Schwartz@weizmann.ac.il
Rosalind Segal
Harvard Medical School
rosalind_segal@dfci.harvard.edu
Uri Seroussi
Tel Aviv University
uriser@gmail.com
9
Vered Shacham
Weizmann Institute of Science
vered.shacham@weizmann.ac.il
Maya Shelly
Stony Brook University
maya.shelly@stonybrook.edu
Ana Maria Soto
Prior-Boulanger
CNRS, Montpellier
ana.boulanger@igh.cnrs.fr
Karen Nadiza Stanic
Aguilera
University of Concepción, Chile
kstanic@udec.cl
Beth Stevens
Boston Children's Hospital,
Harvard Medical School
Beth.Stevens@childrens.harvard.edu
Gohar Ter-Avetisyan
Max Delbrück Center for Molecular Medicine,
Berlin
gohar.teravetisyan@mdc-berlin.de
Marc Tessier-Lavigne
The Rockefeller University
marctl@mail.rockefeller.edu
Wesley Thompson
Texas A&M University
wthompson@bio.tamu.edu
Tracy Tran
Rutgers University
tstran@rutgers.edu
Mengzhe Wang
Technical University of Munich
Mengzhe.Wang@lrz.tu-muenchen.de
Darren Williams
King's College London
darren.williams@kcl.ac.uk
Rachel Wong
University of Washington
wongr2@uw.edu
Shiri Yaniv
Weizmann Institute of Science
shirit.yaniv@weizmann.ac.il
Avraham Yaron
Weizmann Institute of Science
avraham.yaron@weizmann.ac.il
Giuseppe Zaccai
Institut Laue Langevin, France
zaccai@ill.fr
Eitan Erez Zahavi
Sackler School for Medicine, Tel Aviv University
automatic.ze@gmail.com
Hongyan Jenny Zou
Mount Sinai School of Medicine
hongyan.zou@mountsinai.org
10
POSTER LIST
Number Presenter
Institution
Title
P1
Alyagor, I
Weizmann Institute of Science
Systematic approach to uncover the genetic
program underlying axon regrowth during
development
P2
Avraham, O
Hebrew University
Motor and DRG axons serve as choice-points for
the ipsilateral turning of dl3 axons
P3
Barnes, A
Oregon Health and Science University
STRAD pseudokinases regulate morphogenesis in
the developing cerebral cortex
P4
Behar, O
Hebrew University
Astrogliosis induced by brain injury is regulated by
Sema4B phosphorylation
P5
Bornstein, B
Weizmann Institute of Science
The JNK pathway and the adhesion molecule
Fasciclin 2 converge to regulate developmental
pruning
P6
Boulanger, A
CNRS/ Montpellier
Characterization of a novel gene involved in
Drosophila mushroom body ƴ neuron remodeling
P7
Bozek, K
CAS/MPG Shanghai
Role of lipidome in neural development and in
autism
P8
Bradley, P
Ludwig Maximilian University of Munich
The role of postsynaptic activity-related signaling
in de novo synapse formation after spinal cord
injury
P9
Breckwoldt, M
Technische Universität München
Multi-parametric optical analysis of mitochondrial
redox signals during neuronal physiology and
pathology in vivo
P10
Chen, L
Penn State University
Drp1 and caspases negatively regulate Nmnatmediated Trauma-Activated Neuroprotection
(TANP)
P11
Daniel, M
Ben Gurion University of the Negev
The effect of novel telomerase activators on tert
regulation by specific miRNAS using in vitro and in
vivo models: mouse motor neurons like cells and
ALS mice
P12
de Curtis, I
San Raffaele University
Functions of Rac1 and Rac3 GTPases during
GABAergic interneuron maturation and dendritic
spine development
P13
Dębski, J
Polish Academy of Science
Phosphoproteomic profiling of Alzheimer diesease
mouse model synaptosomes
11
Number Presenter
Institution
Title
P14
Degreef, M
Vesalius Research Center
The role of cell surface receptors in the
development and regeneration of the Xenopus
tropicalis nervous system
P15
Doror-Mandel, E Weizmann Institute of Science
Differential subcellular regulation of importin β1 in
nerve injury response
P16
Eggert, B
Universitätsklinikum Hamburg-Eppendorf
Contribution of spatial redistribution of TRPM4 to
inflammation-induced axonal degeneration
P17
Emde, A
Weizmann Institute of Science
MicroRNA dysregulation in amyotrophic lateral
sclerosis
P18
Engerer, P
Technische Universität München
Uncoupling of mitosis and differentiation allows
for fast and synchronous CNS development in vivo
P19
Feinberg, K
The Hospital for Sick Children
Identification of new molecular mechanisms
underlying axonal degeneration
P20
Furlan, A
Karolinska Institutet
Unbiased classification of sensory neuron types by
large-scale single-cell RNA sequencing
P21
Gershoni-Emek, Tel Aviv University
N
microRNA transport in axons of motor neurons:
implications in health and disease
P22
Ghosh, M
Ludwig-Maximilians-University
Role of pericytes in maintenance of vascular
architecture in CADASIL
P23
Gluska, S
Tel Aviv University
Rabies virus exploits the p75NTR retrograde axonal
transport machinery to accelerate its transport to
the CNS
P24
Gobert, D
McGill University
Role of TORC1 in dendritic development and
excitatory synaptic maturation in vivo in the
retinotectal system of Xenopus laevis
P25
Guiretti, D
Instituto de Neurociencias de Alicante
Characterization of a potential novel therapeutical
tool to reverse histone hypoacetylation in
neuropathologies
P26
Gutman, I
Weizmann Institute of Sciences
Glia induce growth arrest of Drosophila α/β
neurons through Myoglianin TGF-β
P27
Hadas, Y
Hebrew University
Functional organization and activity patterns of
spinal dorsal interneurons 1 (dI1) population
P28
Haimson, B
Hebrew University
Deciphering the neuronal circuits that control
patterned limbs versus wings movements in birds
12
Number Presenter
Institution
Title
P29
Hoon, M
University of Washington
Development and maintenance of dendritic and
axonal inhibitory synapses: selective effects of
perturbed neurotransmission
P30
Ibegbu, A
Ahmadu Bello University
Oxidative stress-induced effects on pattern and
pattern formation in cortical B50 neuronal cells in
culture
P31
Jacobi, A
Ludwig-Maximilians-University
FGF signaling dependent synapse formation
during injury-induced induced spinal remodelling
P32
Kapoor, S
National Brain Research Centre
Neuronal remodelling using endogenous stem
cells post ischemic injury: A multidisciplinary
approach
P33
Kaur, R
Vienna University
Molecular mechanisms coordinating sensory
axon branching and targeting in the drosophila
olfactory system
P34
Kleele, T & Brill,
M
Technical University Munich
Cellular mechanisms of neuromuscular synapse
elimination
P35
Kollet, N
Weizmann Institute of Science
Sprouting assay of primary dissociated Drosophila
mushroom body neurons is instrumental in
assessing intrinsic axon growth potential
P36
Lepeta, K
Polish Academy of Science
MMP-9 3’UTR polymorphism and its role in the
onset of schizophrenia. The role in the local
translation
P37
Magiera, M. M.
Université Paris-Sud
Role of tubulin polyglutamylation in neuronal
survival
P38
Maor-Nof, M
Weizmann Institute of Science
Axonal pruning is actively regulated by the
microtubule - destabilizing protein kinesin
superfamily protein 2A
P39
Matho, K
Institut de la Vision
Comprehensive analysis of connectivity in a
central nucleus
P40
Minis, A
Weizmann Institute of Science
LKB1 couples axonal maintenance and energy
homeostasis
P41
Rotem, N
Tel Aviv University
High-Throughput screening for axonal RNAomes
along the process of axon degeneration in
amyotrophic lateral sclerosis
P42
Rumpf, S
UCSF/ HHMI
VCP and ubiquitin regulate dendrite pruning
through a proteolysis-independent role in mRNA
biogenesis
13
Number Presenter
Institution
Title
P43
Saad, Y
Tel-Aviv University
Early growth enhancement and elevated apoptosis
in neuronal cultures of transgenic flies expressing
amyloid-beta 1-42
P44
Sakharchuk, O
Nencki Institute of Experimental Biology
The impact of matrix metalloproteinase 9 on
alcohol-addiction related mouse behavior
P45
Sar Shalom, H
Weizmann Institute of Science
Epigenetic control of axon elimination
P46
Schmidt, S
CNRS
DOCK10 is a Rac1 and Cdc42 activator critical for
dendritic spine morphogenesis
P47
Shacham, V
Weizmann Institute of Science,
Phosphatidylserine exposure marks degenerating
axons
P48
Stanic, K
Universidad de Concepción Chile
Formation of the posterior commissure: a multistep journey of commissural axons
P49
Ter-Avetisyan, G Max Delbrück Center for Molecular
Medicine
Role of a cGMP-dependent signaling pathway in
axonal branching of mesencephalic trigeminal
neurons during the midbrain development
P50
Thompson, W
Texas A&M University
Participation of glia in synapse elimination at the
developing neuromuscular junction
P51
Yaniv, S
Weizmann Institute of Science
Dissecting the role of nuclear receptors in
developmental axon regrowth of mushroom body
neurons
P52
Zahavi, E
Tel Aviv University
Spatial-temporal receptors localization along the
cell membrane as a novel sorting mechanism for
long vs. local signaling
P53
Zou, H
Mount Sinai School of Medicine
Differential phosphorylation of Smad1 integrates
BMP and neurotrophin pathways through Erk/
Dusp in axon development
14
15