Transcript: HIV & AIDS Definition AIDS stands for Acquired Immune Deficiency Syndrome. AIDS is caused by the HIV virus. This virus attacks certain cells of the body's immune system. Over time, the immune system becomes weak. When the immune system starts to fail, the body is susceptible to life-threatening infections and cancers. Eventually, these infections and cancers kill the person who is infected with HIV. Global Statistics By the end of 2000, roughly 36.1 million people worldwide were living with HIV or AIDS. 34.7 million adults and 1.4 million children younger than 15 years are estimated to be infected. About 25.3 million or 70 percent of these cases are in Sub-Saharan Africa. Another 5.8 million or 16 percent live in South and Southeast Asia. These numbers are expected to grow even further as infection rates continue to rise in countries with poverty, poor health systems, and limited resources for prevention and care. HIV & Africa Most of these cases will die in the next 10 years. In Africa, AIDS has already killed 13.7 million Africans, leaving behind shattered families and destroying hope for millions of people. In general, the life expectancy at birth in southern Africa is expected to drop to just 45 years of age between 2005 and 2010 because of AIDS. Without proper education and prevention, AIDS will continue to spread around the world. Sexual Transmission So let's try to understand AIDS by examining the virus that causes it. HIV is spread from person to person by a number of ways. The most common way that HIV is spread is through unprotected sex. High-risk sexual behavior such as sex without a condom or having multiple sexual partners is the most common way HIV is transmitted. Also, having sex while having a sexually transmitted disease, such as chlamydia, gonorrhea, or syphilis, greatly increases the chance of spreading HIV. Recent information suggests that for every 10 African men infected there are between 12 and 13 African women currently infected. What are the reasons for this higher prevalence in women? HIV is spread more effectively from males to females. Also, many women are starting to have sex at a younger age. In fact, the initial age of infection for women is decreasing. 1 Blood Transfusions Another important way of HIV transmission is through blood transfusions. Blood transfusions are given when someone is sick and requires blood. For example, during surgery a person may need a blood transfusion. Blood for blood transfusions is collected at blood donation centers. At these centers, people donate their blood for medical use. Unfortunately, some viruses can be transmitted through blood transfusions, such as HIV. In developed countries, donated blood is routinely checked for viruses and other contaminants. However, in developing countries such as those in Africa and Asia, the technology for blood screening is not often available. For this reason, contaminated blood is a major mode of HIV transmission in places such as sub-Saharan Africa. Contaminated Needles HIV can also be transmitted through the use of contaminated needles. Hospital needles should only be used once and then properly disregarded. People who use IV drugs, such as heroin, often share needles and reuse them many times. HIV transmission is high among those who use IV drugs. Myths About HIV It is important to know that HIV cannot be transmitted by casual contact with HIV infected people, like shaking hands or even kissing. The HIV virus is not spread through the air either. The HIV virus needs some sort of biological fluid to transfer itself to another person. Usually this fluid is blood. Life Cycle So how does HIV affect the body? Let's look at the life cycle of HIV. When HIV is contracted, it circulates in the blood and spreads throughout the body. When the HIV virus finds a cell called the CD4 cell, it attaches to it. The CD4 cell is very important in helping the body fight infections. The virus enters this cell and begins to multiply. As it begins to create more viruses, the CD4 cell cannot properly function. In essence, the CD4 cell has become a factory for producing even more HIV viruses. Finally, the CD4 cell dies and all the newly formed HIV viruses are released back into the blood stream. These new viruses then seek out other CD4 cells. The cycle repeats itself until the body's CD4 level is so low that the person can not fight infections and cancer. Eventually, this is what kills the HIV infected person. Treatment Today, there is no cure for AIDS. Scientists have developed ways of helping the body fight HIV. Many of the new drugs that fight HIV are available in the developed countries, but are not as available in countries in Africa and Asia. Also, these drugs are very expensive and must be taken several times a day. People who take these drugs also report feeling weak and sick. While these drugs may prolong the person's life, no drug can cure a person with HIV. Scientists have also been trying to develop vaccines against HIV but this has not been successful. 2 Prevention Prevention is the best way to fight HIV infection. Safe sex should always be practiced by using a condom properly. A condom should never be used more than once, and should be checked for tears or holes. Individuals should avoid having more than one sexual partner and avoid sex completely if there are open sores or lesions on the genitals. IV drug use should also be stopped completely. Hospital needles should never be used twice and should be disposed of properly to avoid accidents. Donated blood should be screened before making it available for blood transfusion. The ELISA test is performed in a laboratory for HIV screening of donated blood. Diagnostic Tests People who may be at risk for HIV should be tested frequently. The Hema-Strip HIV test can give accurate results in just five minutes. It does not require special machines or lab conditions and is effective for testing for HIV in the field. The Hema-strip HIV is very simple to use. First, prick the finger with the lancet. Next, place the capillary tip of the sampler on the blood drop. Carefully remove the buffer vial from the top of the sampler. Gently push the capillary tip of the sampler completely into the buffer. Wait five minutes for the results to appear. One red line indicates that the test is negative. This means that the test was performed appropriately and that the blood sample does not contain antibodies to the HIV virus. Two red lines indicate that the test is positive and that the person is infected with the HIV virus. Closing Remarks Even though there is no cure for AIDS, educating the HIV positive person about AIDS and high-risk behavior can help decrease transmission to others. Also, as more effective drugs become available, HIV infected individuals can begin to lead a normal life. 3