Review: ­ types of hormones ­ glands and their hormones ­ hormones of the pituitary gland ­ negative and positive feedback loops Oct 14­3:05 PM Regulation of Blood Sugar ­ this a negative feedback loop controlled by two antagonistic hormones ­ insulin converts glucose into glycogen and lowers blood sugar ­ glucagon converts stored glycogen into glucose causing an increase in blood sugar ­ regulation of blood sugar follows a number of steps Oct 14­3:06 PM 1 Step 1: Low levels of blood sugar stimulate the secretion of glucagon Step 2: Increased glucagon causes stored glycogen in the liver to be converted into glucose for release into the blood stream Step 3: As blood sugar levels rise the glucagon stops but high blood sugar levels result in the release of insulin Step 4: Increased insulin levels cause the intake of glucose into muscle cells and convert excess glucose into glycogen for storage in the liver Step 5: When blood sugar levels drop the cycle starts again. Oct 14­3:08 PM Insulin (pancreas) High Blood Sugar Normal Blood Sugar Low Blood Sugar Glucagon (pancreas) Cortisol (pancreas) Oct 14­3:13 PM 2 Disorders of the Pancreas a. Type 1 Diabetes (Diabetes Mellitus) ­ known as juvenile or insulin dependent diabetes (occurs in people under 20) ­ cause by lack of insulin production in the pancreas ­ results in high levels of sugar (glucose) in the blood ­ symptoms include fatigue, thirst, frequent urination, possible blindness ­ treatments include insulin injection (for life) Oct 14­3:17 PM b. Type 2 Diabetes (Adult onset diabetes) ­ occurs in people over 40 years old ­ insulin is produced by the pancreas but cells do not recognize it ­ cells do not use the sugar found in the blood ­ treatment includes a strict control of carbohydrate intake to reduce the amount of blood sugar in the blood Oct 14­3:30 PM 3 Disorders of the Endocrine System ­ see sheet provided 1. Dwarfism: Oct 20­8:02 PM 2. Giantism: Oct 21­7:52 AM 4 3. Hyperthyroidism: Oct 21­7:54 AM 4. Hypothyroidism: Oct 21­7:55 AM 5 5. Diabetes Mellitus: Oct 21­7:57 AM Readings Pages 427 ­ 440 (Be sure to read section on Banting and Best on page 439) Oct 14­3:34 PM 6 Review: Text: pages 420 ­ 446 Questions: pg. 447, #'s 2,5,6,8,9,10,11,17,20 pg.452, #'s 37,52,53 jeopardy1288971466 Oct 22­9:16 AM 7